BGC0001241: ergotamine biosynthetic gene cluster from Claviceps fusiformis
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Location: 1 - 77,498 nt. (total: 77,498 nt).
This entry is originally from NCBI GenBank JN186799.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001241
Short description ergotamine biosynthetic gene cluster from Claviceps fusiformis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
JN186799.1
via
Compounds
  • ergotamine
  • ergocryptine
Species Claviceps fusiformis [taxonomy]
References
Chemical products information
ergotamine Evidence: Mass spectrometry [1]
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C33H35N5O5
Chemical database entries
ChEMBL
PubCHEM
ChemSpider
ergocryptine [synonyms: α-ergocryptine, alpha-ergocryptine] Evidence: Mass spectrometry [1]
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Chemical database entries
ChEMBL
ChemSpider
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AET79187.1
  • leuCD
 708 - 3321 (+) 3-isopropylmalate dehydratase
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    • AET79176.1
    		 6589 - 8245 (+) hypothetical protein
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      • AET79177.1
      • lpsC
      		 8839 - 14264 (-) lysergyl peptide synthetase subunit 3
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        • AET79178.1
        • easA
        		 15341 - 16483 (-) chanoclavine-I aldehyde oxidoreductase
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          • AET79179.1
          • lpsB
          		 17028 - 21003 (+) lysergyl peptide synthetase subunit 2
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            • AET79191.1
            • cloA
            		 21324 - 23435 (-) elymoclavine monooxygenase
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              • AET79180.1
              • easC
              		 24095 - 25602 (-) chanoclavine synthase catalase protein
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                • AET79189.1
                • easD
                		 26331 - 27179 (-) chanoclavine-I dehydrogenase
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                  • AET79192.1
                  • easE
                  		 27587 - 29490 (+) chanoclavine-I synthase oxidoreductase
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                    • AET79190.1
                    • easF
                    		 29844 - 30993 (+) dimethylallyltryptophan N-methyltransferase
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                      • AET79181.1
                      • easG
                      		 31353 - 32431 (-) agroclavine dehydrogenase
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                        • AET79188.1
                        • dmaW
                        		 33089 - 34554 (+) dimethylallyl tryptophan synthase
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                          • AET79182.1
                          • easH1
                          		 35947 - 36891 (-) putative oxygenase
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                            • AET79183.1
                            • lpsA1
                            		 37705 - 48636 (+) lysergyl peptide synthetase subunit 1
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                              • AET79184.1
                              • lpsA2
                              		 52447 - 63381 (+) lysergyl peptide synthetase subunit 1
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                                • AET79185.1
                                		 66909 - 67226 (+) hypothetical protein
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                                  • AET79186.1
                                  		 69960 - 71064 (-) hypothetical protein
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                                    Biosynthesis information
                                    Annotation changelog

                                    Entry version: next

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2024-06-12
                                    MIBiG v4 annotathon
                                    • (ID: D44UGPXERIZAXNCG2VXZP5I3)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Corrected organism and accession
                                    • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2022-09-15
                                    Added additional publication
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2022-09-15
                                    Fix organism name
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2015-12-24
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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