LOCUS       BGC0001250             14073 bp    DNA     linear   PLN 10-MAY-2013
DEFINITION  Epichloe festucae strain E2368 epichloenin A synthetase (sidN) gene,
            complete cds.
ACCESSION   BGC0001250
VERSION     BGC0001250
KEYWORDS    .
SOURCE      Epichloe festucae
  ORGANISM  Epichloe festucae
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Epichloe.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 00:16:24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14073
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..14073
                     /db_xref="taxon:35717"
                     /mol_type="genomic DNA"
                     /organism="Epichloe festucae"
                     /strain="E2368"
     mRNA            <1..>14073
                     /gene="sidN"
                     /product="epichloenin A synthetase"
     gene            <1..>14073
                     /gene="sidN"
     protocluster    1..14073
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:14073]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..14073
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..14073
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..14073
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001250"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..14073
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1..14073
                     /NRPS_PKS="Domain: AMP-binding (236-657). E-value: 5.7e-73.
                     Score: 237.6. Matches aSDomain:
                     nrpspksdomains_sidN_AMP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (926-1174). E-value:
                     1.5e-24. Score: 78.5. Matches aSDomain:
                     nrpspksdomains_sidN_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1348-1760). E-value:
                     2.5e-79. Score: 258.6. Matches aSDomain:
                     nrpspksdomains_sidN_AMP-binding.2"
                     /NRPS_PKS="Domain: PKS_PP (1822-1962). E-value: 2.3e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_sidN_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1999-2283). E-value:
                     5.7e-25. Score: 79.9. Matches aSDomain:
                     nrpspksdomains_sidN_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2462-2869). E-value: 6e-72.
                     Score: 234.3. Matches aSDomain:
                     nrpspksdomains_sidN_AMP-binding.3"
                     /NRPS_PKS="Domain: PP-binding (3009-3073). E-value:
                     1.3e-09. Score: 30.3. Matches aSDomain:
                     nrpspksdomains_sidN_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (3116-3407). E-value:
                     1.1e-40. Score: 131.4. Matches aSDomain:
                     nrpspksdomains_sidN_Condensation_DCL.3"
                     /NRPS_PKS="Domain: PKS_PP (3565-3635). E-value: 5.2e-08.
                     Score: 25.0. Matches aSDomain:
                     nrpspksdomains_sidN_PKS_PP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (3677-3957). E-value:
                     4.1e-38. Score: 123.0. Matches aSDomain:
                     nrpspksdomains_sidN_Condensation_DCL.4"
                     /NRPS_PKS="Domain: PP-binding (4127-4189). E-value:
                     2.7e-08. Score: 26.1. Matches aSDomain:
                     nrpspksdomains_sidN_PP-binding.2"
                     /NRPS_PKS="Domain: Condensation_DCL (4262-4528). E-value:
                     9.8e-36. Score: 115.2. Matches aSDomain:
                     nrpspksdomains_sidN_Condensation_DCL.5"
                     /codon_start=1
                     /gene="sidN"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     198.1; E-value: 3.3e-60)"
                     /gene_kind="biosynthetic"
                     /product="epichloenin A synthetase"
                     /protein_id="AET13875.1"
                     /sec_met_domain="Condensation (E-value: 1.1e-42, bitscore:
                     132.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-86, bitscore:
                     276.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-11, bitscore:
                     30.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDQVAVTRFPALHCFEGPKQRQSVGSNARHHTIRGNIDTQHQSQD
                     ETLRRFANFVSSLVGDDEISFDFIISPSNGGSDIAESGTAQAKKDPTQATSDYNGITLL
                     RSTPFVESGHSEFGIIIRRQLRNNDSSLFTLEKSFVVAVDKSSYSVRICRDLVPRPLLQ
                     SISTSLCSYMGWTNPSQHSEEESNQELQLQTLNFQGQSVLNHPPLMTPPDFESQLCLPK
                     RPQEYAKPLLHNAFLARVRENPGRIALDALSSTGRATYTYKSLDDLSSDLAEKILQIIG
                     VDADHTDRNITVALSTSAELYIAWLGILKAGCVVSPVPTDCPSGLLQHMTGLTSSKVVL
                     GSAETLEYFDRIIGDSSTFTFINVETIARQNYEHLLQRPPPLVNTSENDVAYILFTSGS
                     TGKPKGVQITHHAAVCSIAANIAASPYSFESGPSSIRWFQMAAPTFDLSVLEIFVTFSI
                     GGTICACDRTMMLTDAESVITQLEATITMTTPTLASLLRPSRIPKLREVWVCGEMLKRE
                     ASELFARDRDPSVADGDTNLLNAYGPTEATITCTVDARVSLKHRGSLIGPPLPTCSNII
                     LDSSEPPKAVPLGFAGELAIGGPQLSIGYLKSPEKTAAAFVDVEPYGKLYRTGDMARLI
                     MGPDGTLQVEFLGRLSSDQIKILGRRVELGEIEAGLRNPLIAEVAAVALKPEVSGLPQV
                     QLIAVVTCRTEKSDSDILAACQERAENVLQPHMRPSIYYVMDKLPRLASEKTDRKTLAK
                     YCLSPEKSGLRRLRNGDVDGHREAGSSSIPMLQSVIEAVSSVAIVGSDKITSATTLLSL
                     GIDSLRSVRLLQNFREIGIEGLQVTDILTCHNLGDLDTKAQQALNRSTPSLAKARNLQT
                     LLIDFENRHKKQCLSALGFNEDNIVSFLPVTTSQAVALASFLLTADANGFQAVPGGKAF
                     IQHTVYTVKPELNSQRIVESWTRVLSRYDIMRSVFVEVNDDLTPFAQCILSPDHEAAQI
                     KPHFYSAKSDNECKDVIQAAQKAAEEKISLYEPPRRLSVVQSPTQTIIVFSQLHSVFDG
                     GSETLLLEDIEREYFGQPSIERTGVLTAVERHFSENRAEAAQFWQAYMDGFLSPSFPCL
                     RSTVPGPDENVCGGYSFMSDLSLESLTRQAAALQCSPLSILQAAWAQILFTYTGERDVA
                     FGNTMSGRFTTELVNCSAPVLTIQSTRVNLNEENDKRNIDILLERTAQNTAALSYLHTP
                     ITGARYDTTIALQMYLNSGKGEALYERVCHPGMQNDLAVMIEVYPDRSGLLEFRLTYQT
                     ALLDDDAAYTMLANLARVTNHIMSYPNAKYMDPSVWTSLQGPGQLEQINGYHHLGQQLL
                     HECVAEFAQKSPNAIALAFYDDLSVDHPKVQLTYADLEVKATRVAGFLMSQLPAKEGSK
                     HVVPIFMEKCPELYITLLGILKAGAAWCPVDPSYPPARQIFLIEKTTAGICFTSKSTTS
                     QLSSILPASFKSISVSDLLEGGSCSTSRTLKASESARLDNLSIQRSDIAYVIFTSGTTG
                     TPKGVPISHESASLSIDSYIQRVNVDLDLRGCEVRFLQFANYTFDAFVCDVFTAWRLGG
                     TLVSATRDILLGSFIALANKVGATHTSMTPTFASTLQPQDFETLRVATMGGEVLPQILA
                     DKWKSRMSLCNVYGPAETAINTTINRLSAASRSGNIGTALPAVNAYVMASGYPVMKHML
                     GELVISGPQLSPGYWDNVHSSNNRFRWNSTLQCRVYHTGDYVRQLADGSFDFVGRKDDL
                     VKIRGMRVELTEISTVCSAGHESVVHSEVLLAKLPGSTQSSLICFVDCGLQKSSDVDNF
                     CILKNEEAQLVAQAVKRHATAELPRHMVPDVFMPLNCLPRNQSSKVNRKRLLEVIGREW
                     SMQPMSPVADEQVDPAWCIKHRPLLEKIQGVIKIMPTTLSRSTTLSELGVDSIGAIRLS
                     SRLKNDGHDISAIQVLDSVTIEDLINHLSVKRQGTSNWKTLLSRYLDHWKPLVSRHLAR
                     DPAHFSLVPTTVFQDGMLVETLRDPMLYWASYSWRLPSTVDIARVRQAWQHVSKNHDIL
                     KVSFVPTAYFEQEETQSSGPSSMFIQLIDYNASMGWQEIVSDSGDWQQSIHALCANLQR
                     TQHENNFSSPPWRVTILAQQDQRIMNLTIHHSLCDGEMLRSLMHDVAWAYSTAELPVKR
                     CQVQEAVSRLAVRYSEPEGHKFWGDMLSPLVSQTSLGDATSNSPKAVVRKIRHRTTELQ
                     ATRSTSKLTGLARRLGASSLSPLFRVTFGIMLTEYYEQQSVLFGEVRSERLLESQLVGA
                     MAPLSATYPVPFRSSGNLKDMVHSQQILVMDSIRYGPPQPSDVRKILKKSRDEALYSAV
                     YVLRQRSEDDGGSLAPWEEFKDIFEIFVDHEFALNVLEGADDTVTISLSVDETLMSSSA
                     QAIFLQQLDALLIAFDKSAPEISLSGLNAHFPLDLLSIASSKVSAQYTSTVPPSHYIET
                     WAKTHPEWKAVEVATGFLGSQKIVTEDWTYKKLNETANQVANLIIHASLHGRAIAVSLD
                     RSLIAFAIIVGIMKSGNTYVPIEAGLPNDRKSFLLRDSRAAMAFVCDNNFDGVELPPET
                     KVLDTKNQSFIENLSTQDTSDILNNYPENLDAYLLYTSGSTGAPKGVRVSRHNLSSFSD
                     AWGKLIGNVAPKSLELGGVGKFLCLASRAFDVHIGEMFLAWRFGLCAVTGERLSMLDDL
                     PRTFRELGVTHAGIVPSLLDQTGLVPEDAPHLVYLGVGGEKMTPRTQQIWSSSDRVALV
                     NVYGPTEVTIGCSAGRILPDSDTRCIGHPLGDSVAHVLAPGSNEHVKKGMAGELVIEGS
                     LVANGYLNRPDAKGFCDINGRKMYRTGDIVRMDADSSILFLGRKDEQVKVRGQRLELGE
                     VSEVIRSLSPTDIDVVTLLLNHPGTSKQFLVSFVASSGAAVRGELRWINENYKEINNSL
                     RQACEQTLPAYMVPDFIIPISFIPLRDTSAKTDAKALEHMFHTLSLGELFGESSSLVNK
                     PTTAPSRDLTSIEKQILTVVKSVVGQDDKRDARPGSTLFQLGLDSIASVKLSFKLKKLG
                     FSTTVARLLQNPTIEELGRMKNALKGSHHAEPSNSESITTRFEELEKETMNSLKDRETT
                     HIESIRPCMPLQEVLVAHTMSHGSEADNAYVSHMIFELDPAVVVEHVKAAWAAVVKNTE
                     LLRTCFIDRENDIVQLVIKENHATPVWKHLSNGTNMLKEELLSCKKEIADDIVTNIDKS
                     PPVRFTLASCDGADETNEMSLFMLSIHHALYDMVSIEMIFQDFEVAYTDSSLSRRPSTL
                     PLLEHIAAQQQNESKAKSYWTTLFDGYDHRIEKISPRTAQTTARTLNASLTTLESLCSQ
                     TNMTLSALIQGVFAYVLARTLKRPDLIFGVVLSGRSIDVEGIDAMAAPCISTIPQRLNI
                     GTDGETIAELITTVQDRLFKSMEYQYTSLRSLSRWLEISGPLFSSLFSFTKLSPPEDSG
                     SSKSRILKPTEGEMFLDFELALECEADPGTDTVTLRTRSTMFDKMEELDALLEQMESLV
                     TSFTRGENKAVDGDFGSMLHTRLLPPHGSLQEESDDWSVLEQQIRDVVVAFSGASPNEV
                     KRTTPFIKYGIDSITTIRFSTLLRKNGFWVSGADVLRNPSVAKLATHIQTTSSFNGTAK
                     DSDDEASESAGIGNWSKALLAGAVSTKVLDDVVAVYPLTPLQAGMISATVMMDPTLYAH
                     HHPFRLPQGTSIDQVRSAWSRLVAKHDILRTSFHEINQPRPQLVGAVHQESILNWHEVA
                     TEDVQVAIDDLIKRTQFPSVSSFETPPVKATVIRSPEDMLLVVSLHHATYDGTSIRFIF
                     EDLWAILRGNRVPERNPFYETAMKIHNMSSGSVGFWADSLSGYGGAAAIAEAEDIQNKM
                     TSKTMLLAQDTSALEQWCTEKGITIQTICQLAVSKAVCAQTKSRDVVLGQVHAARLDIN
                     GADKVAGPMLNTVPLRLCIHDDSFTNHDYLRDLQAFQNKSLDHLHASLSDIQRLWRKEN
                     GRDGQLFEVLFIFRKGEDATEAPFWQPFEPEGSKESLPPSHYDLVIEVHQKSRGGLELE
                     VHSRFADDTTSNLMSLLVESFESIRKHPDELAISSPGVLSKVPKPGLTRETGAVPTSPF
                     DQSAIDQFLDPLRKVLSETTDTPVSSIDAQTSIFSIGVDSIVAIRVAGACRKAHIPLHT
                     MEIMRNAKIGKLCEVAFAKSGQAAPNRSTTESNGVAPLLDQEVKKAAASKLGRAEAEIQ
                     EILPVLPGQEYHLACWLTSGKTLLEPVWVFKAENGLDAGRLRDTWISLVQKNDSLRTCF
                     AQVKPTLAVQAILKPDCVDAAKSFTVQQVPENMTMEEYVKSEIHHLSLSPSSLYEPPVR
                     IVLIQGGREGVSVLLRLHHALYDAWSMGILIDELSSLYCGTMQKPCPPLSVSHFAQFTQ
                     QKLRGKNEEQFWTETLGQCDPTILTPKADINTDSKSCNRAFVSFECVDVSMGALKSAAR
                     AFGITPQCLIQVAFGRMLSDVTESSSPVFGYYTAGRSAELEGIEALASPTLNMLPVAVP
                     KDLVASQLAGTSLSILLQSFQDRTNSQSDYEQSRLRDVIKWAPNKGVSPLFNAHLNILW
                     NDEILLKPQVSKDTLLRPWPLGVPSDYASPTPLSRGSSVDGLDTSFLPTNVLFADVGPS
                     RETANLAIGIGCDPTLRDAQGLEEIARMFSGHLSRLVGSRDLV"
     aSDomain        709..1971
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_AMP-binding.1"
                     /evalue="5.70E-73"
                     /label="sidN_AMP-binding.1"
                     /locus_tag="sidN"
                     /protein_end="657"
                     /protein_start="236"
                     /score="237.6"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="LARVRENPGRIALDALSSTGRATYTYKSLDDLSSDLAEKILQIIG
                     VDADHTDRNITVALSTSAELYIAWLGILKAGCVVSPVPTDCPSGLLQHMTGLTSSKVVL
                     GSAETLEYFDRIIGDSSTFTFINVETIARQNYEHLLQRPPPLVNTSENDVAYILFTSGS
                     TGKPKGVQITHHAAVCSIAANIAASPYSFESGPSSIRWFQMAAPTFDLSVLEIFVTFSI
                     GGTICACDRTMMLTDAESVITQLEATITMTTPTLASLLRPSRIPKLREVWVCGEMLKRE
                     ASELFARDRDPSVADGDTNLLNAYGPTEATITCTVDARVSLKHRGSLIGPPLPTCSNII
                     LDSSEPPKAVPLGFAGELAIGGPQLSIGYLKSPEKTAAAFVDVEPYGKLYRTGDMARLI
                     MGPDGTLQVEFLGRLSSDQIKI"
     CDS_motif       916..954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0001"
                     /evalue="4.30E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="sidN"
                     /protein_end="318"
                     /protein_start="305"
                     /score="4.7"
                     /tool="antismash"
                     /translation="LGILKAGCVVSPV"
     CDS_motif       1171..1230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0002"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="sidN"
                     /protein_end="410"
                     /protein_start="390"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYILFTSGSTGKPKGVQITH"
     CDS_motif       1621..1650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0003"
                     /evalue="7.10E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="sidN"
                     /protein_end="550"
                     /protein_start="540"
                     /score="6.3"
                     /tool="antismash"
                     /translation="YGPTEATITC"
     CDS_motif       1759..1848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0004"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="sidN"
                     /protein_end="616"
                     /protein_start="586"
                     /score="33.7"
                     /tool="antismash"
                     /translation="PLGFAGELAIGGPQLSIGYLKSPEKTAAAF"
     CDS_motif       1954..2004
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0005"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="sidN"
                     /protein_end="668"
                     /protein_start="651"
                     /score="16.9"
                     /tool="antismash"
                     /translation="SDQIKILGRRVELGEIE"
     aSDomain        2779..3522
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.50E-24"
                     /label="sidN_Condensation_DCL.1"
                     /locus_tag="sidN"
                     /protein_end="1174"
                     /protein_start="926"
                     /score="78.5"
                     /tool="antismash"
                     /translation="GKAFIQHTVYTVKPELNSQRIVESWTRVLSRYDIMRSVFVEVNDD
                     LTPFAQCILSPDHEAAQIKPHFYSAKSDNECKDVIQAAQKAAEEKISLYEPPRRLSVVQ
                     SPTQTIIVFSQLHSVFDGGSETLLLEDIEREYFGQPSIERTGVLTAVERHFSENRAEAA
                     QFWQAYMDGFLSPSFPCLRSTVPGPDENVCGGYSFMSDLSLESLTRQAAALQCSPLSIL
                     QAAWAQILFTYTGERDVAFGNTMSGR"
     aSModule        2779..5886
                     /complete
                     /domains="nrpspksdomains_sidN_Condensation_DCL.1"
                     /domains="nrpspksdomains_sidN_AMP-binding.2"
                     /domains="nrpspksdomains_sidN_PKS_PP.1"
                     /locus_tags="sidN"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2785..2898
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0006"
                     /evalue="6.90E-06"
                     /label="C2_DCL_024-062"
                     /locus_tag="sidN"
                     /protein_end="966"
                     /protein_start="928"
                     /score="18.4"
                     /tool="antismash"
                     /translation="AFIQHTVYTVKPELNSQRIVESWTRVLSRYDIMRSVFV"
     CDS_motif       3127..3174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0007"
                     /evalue="3.00E+00"
                     /label="C3_LCL_132-143"
                     /locus_tag="sidN"
                     /protein_end="1058"
                     /protein_start="1042"
                     /score="0.9"
                     /tool="antismash"
                     /translation="HSVFDGGSETLLLEDI"
     aSDomain        4045..5280
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_AMP-binding.2"
                     /evalue="2.50E-79"
                     /label="sidN_AMP-binding.2"
                     /locus_tag="sidN"
                     /protein_end="1760"
                     /protein_start="1348"
                     /score="258.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="EFAQKSPNAIALAFYDDLSVDHPKVQLTYADLEVKATRVAGFLMS
                     QLPAKEGSKHVVPIFMEKCPELYITLLGILKAGAAWCPVDPSYPPARQIFLIEKTTAGI
                     CFTSKSTTSQLSSILPASFKSISVSDLLEGGSCSTSRTLKASESARLDNLSIQRSDIAY
                     VIFTSGTTGTPKGVPISHESASLSIDSYIQRVNVDLDLRGCEVRFLQFANYTFDAFVCD
                     VFTAWRLGGTLVSATRDILLGSFIALANKVGATHTSMTPTFASTLQPQDFETLRVATMG
                     GEVLPQILADKWKSRMSLCNVYGPAETAINTTINRLSAASRSGNIGTALPAVNAYVMAS
                     GYPVMKHMLGELVISGPQLSPGYWDNVHSSNNRFRWNSTLQCRVYHTGDYVRQLADGSF
                     DFVGRKDDLVKIR"
     CDS_motif       4258..4299
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0008"
                     /evalue="7.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="sidN"
                     /protein_end="1433"
                     /protein_start="1419"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LGILKAGAAWCPVD"
     CDS_motif       4528..4587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0009"
                     /evalue="3.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="sidN"
                     /protein_end="1529"
                     /protein_start="1509"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYVIFTSGTTGTPKGVPISH"
     CDS_motif       4951..4980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0010"
                     /evalue="1.10E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="sidN"
                     /protein_end="1660"
                     /protein_start="1650"
                     /score="3.0"
                     /tool="antismash"
                     /translation="YGPAETAINT"
     CDS_motif       5092..5142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0011"
                     /evalue="5.40E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="sidN"
                     /protein_end="1714"
                     /protein_start="1697"
                     /score="15.6"
                     /tool="antismash"
                     /translation="GELVISGPQLSPGYWDN"
     CDS_motif       5245..5307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0012"
                     /evalue="8.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="sidN"
                     /protein_end="1769"
                     /protein_start="1748"
                     /score="27.6"
                     /tool="antismash"
                     /translation="FVGRKDDLVKIRGMRVELTEI"
     aSDomain        5467..5886
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_PKS_PP.1"
                     /evalue="2.30E-10"
                     /label="sidN_PKS_PP.1"
                     /locus_tag="sidN"
                     /protein_end="1962"
                     /protein_start="1822"
                     /score="32.6"
                     /tool="antismash"
                     /translation="AQLVAQAVKRHATAELPRHMVPDVFMPLNCLPRNQSSKVNRKRLL
                     EVIGREWSMQPMSPVADEQVDPAWCIKHRPLLEKIQGVIKIMPTTLSRSTTLSELGVDS
                     IGAIRLSSRLKNDGHDISAIQVLDSVTIEDLINHLS"
     aSDomain        5998..6849
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_Condensation_DCL.2"
                     /domain_subtype="Condensation_DCL"
                     /evalue="5.70E-25"
                     /label="sidN_Condensation_DCL.2"
                     /locus_tag="sidN"
                     /protein_end="2283"
                     /protein_start="1999"
                     /score="79.9"
                     /tool="antismash"
                     /translation="VPTTVFQDGMLVETLRDPMLYWASYSWRLPSTVDIARVRQAWQHV
                     SKNHDILKVSFVPTAYFEQEETQSSGPSSMFIQLIDYNASMGWQEIVSDSGDWQQSIHA
                     LCANLQRTQHENNFSSPPWRVTILAQQDQRIMNLTIHHSLCDGEMLRSLMHDVAWAYST
                     AELPVKRCQVQEAVSRLAVRYSEPEGHKFWGDMLSPLVSQTSLGDATSNSPKAVVRKIR
                     HRTTELQATRSTSKLTGLARRLGASSLSPLFRVTFGIMLTEYYEQQSVLFGEVRSERLL
                     ESQ"
     aSModule        5998..9219
                     /complete
                     /domains="nrpspksdomains_sidN_Condensation_DCL.2"
                     /domains="nrpspksdomains_sidN_AMP-binding.3"
                     /domains="nrpspksdomains_sidN_PP-binding.1"
                     /locus_tags="sidN"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6070..6168
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0013"
                     /evalue="1.80E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="sidN"
                     /protein_end="2056"
                     /protein_start="2023"
                     /score="17.0"
                     /tool="antismash"
                     /translation="YSWRLPSTVDIARVRQAWQHVSKNHDILKVSFV"
     CDS_motif       6415..6480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0014"
                     /evalue="1.00E+00"
                     /label="C3_DCL_135-156"
                     /locus_tag="sidN"
                     /protein_end="2160"
                     /protein_start="2138"
                     /score="2.3"
                     /tool="antismash"
                     /translation="IHHSLCDGEMLRSLMHDVAWAY"
     aSDomain        7387..8607
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_AMP-binding.3"
                     /evalue="6.00E-72"
                     /label="sidN_AMP-binding.3"
                     /locus_tag="sidN"
                     /protein_end="2869"
                     /protein_start="2462"
                     /score="234.3"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ETWAKTHPEWKAVEVATGFLGSQKIVTEDWTYKKLNETANQVANL
                     IIHASLHGRAIAVSLDRSLIAFAIIVGIMKSGNTYVPIEAGLPNDRKSFLLRDSRAAMA
                     FVCDNNFDGVELPPETKVLDTKNQSFIENLSTQDTSDILNNYPENLDAYLLYTSGSTGA
                     PKGVRVSRHNLSSFSDAWGKLIGNVAPKSLELGGVGKFLCLASRAFDVHIGEMFLAWRF
                     GLCAVTGERLSMLDDLPRTFRELGVTHAGIVPSLLDQTGLVPEDAPHLVYLGVGGEKMT
                     PRTQQIWSSSDRVALVNVYGPTEVTIGCSAGRILPDSDTRCIGHPLGDSVAHVLAPGSN
                     EHVKKGMAGELVIEGSLVANGYLNRPDAKGFCDINGRKMYRTGDIVRMDADSSILFLGR
                     KDEQVKVR"
     CDS_motif       7600..7635
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0015"
                     /evalue="6.00E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="sidN"
                     /protein_end="2545"
                     /protein_start="2533"
                     /score="7.3"
                     /tool="antismash"
                     /translation="GIMKSGNTYVPI"
     CDS_motif       7840..7896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0016"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="sidN"
                     /protein_end="2632"
                     /protein_start="2613"
                     /score="23.3"
                     /tool="antismash"
                     /translation="AYLLYTSGSTGAPKGVRVS"
     CDS_motif       8284..8307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0017"
                     /evalue="8.10E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="sidN"
                     /protein_end="2769"
                     /protein_start="2761"
                     /score="3.4"
                     /tool="antismash"
                     /translation="YGPTEVTI"
     CDS_motif       8422..8487
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0018"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="sidN"
                     /protein_end="2829"
                     /protein_start="2807"
                     /score="26.9"
                     /tool="antismash"
                     /translation="GMAGELVIEGSLVANGYLNRPD"
     CDS_motif       8572..8634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0019"
                     /evalue="4.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="sidN"
                     /protein_end="2878"
                     /protein_start="2857"
                     /score="31.6"
                     /tool="antismash"
                     /translation="FLGRKDEQVKVRGQRLELGEV"
     aSDomain        9028..9219
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_PP-binding.1"
                     /evalue="1.30E-09"
                     /label="sidN_PP-binding.1"
                     /locus_tag="sidN"
                     /protein_end="3073"
                     /protein_start="3009"
                     /score="30.3"
                     /tool="antismash"
                     /translation="QILTVVKSVVGQDDKRDARPGSTLFQLGLDSIASVKLSFKLKKLG
                     FSTTVARLLQNPTIEELGR"
     aSDomain        9349..10221
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_Condensation_DCL.3"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.10E-40"
                     /label="sidN_Condensation_DCL.3"
                     /locus_tag="sidN"
                     /protein_end="3407"
                     /protein_start="3116"
                     /score="131.4"
                     /tool="antismash"
                     /translation="SIRPCMPLQEVLVAHTMSHGSEADNAYVSHMIFELDPAVVVEHVK
                     AAWAAVVKNTELLRTCFIDRENDIVQLVIKENHATPVWKHLSNGTNMLKEELLSCKKEI
                     ADDIVTNIDKSPPVRFTLASCDGADETNEMSLFMLSIHHALYDMVSIEMIFQDFEVAYT
                     DSSLSRRPSTLPLLEHIAAQQQNESKAKSYWTTLFDGYDHRIEKISPRTAQTTARTLNA
                     SLTTLESLCSQTNMTLSALIQGVFAYVLARTLKRPDLIFGVVLSGRSIDVEGIDAMAAP
                     CISTIPQRLN"
     aSModule        9349..10905
                     /domains="nrpspksdomains_sidN_Condensation_DCL.3"
                     /domains="nrpspksdomains_sidN_PKS_PP.2"
                     /incomplete
                     /locus_tags="sidN"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9424..9537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0020"
                     /evalue="3.60E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="sidN"
                     /protein_end="3179"
                     /protein_start="3141"
                     /score="25.7"
                     /tool="antismash"
                     /translation="AYVSHMIFELDPAVVVEHVKAAWAAVVKNTELLRTCFI"
     CDS_motif       9760..9822
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0021"
                     /evalue="5.00E-03"
                     /label="NRPS-E2"
                     /locus_tag="sidN"
                     /protein_end="3274"
                     /protein_start="3253"
                     /score="9.7"
                     /tool="antismash"
                     /translation="MLSIHHALYDMVSIEMIFQDF"
     CDS_motif       10120..10215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0022"
                     /evalue="4.70E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="sidN"
                     /protein_end="3405"
                     /protein_start="3373"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DLIFGVVLSGRSIDVEGIDAMAAPCISTIPQR"
     CDS_motif       10267..10371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0023"
                     /evalue="2.60E-02"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="sidN"
                     /protein_end="3457"
                     /protein_start="3422"
                     /score="6.9"
                     /tool="antismash"
                     /translation="QDRLFKSMEYQYTSLRSLSRWLEISGPLFSSLFSF"
     aSDomain        10696..10905
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_PKS_PP.2"
                     /evalue="5.20E-08"
                     /label="sidN_PKS_PP.2"
                     /locus_tag="sidN"
                     /protein_end="3635"
                     /protein_start="3565"
                     /score="25.0"
                     /tool="antismash"
                     /translation="LEQQIRDVVVAFSGASPNEVKRTTPFIKYGIDSITTIRFSTLLRK
                     NGFWVSGADVLRNPSVAKLATHIQT"
     aSDomain        11032..11871
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_Condensation_DCL.4"
                     /domain_subtype="Condensation_DCL"
                     /evalue="4.10E-38"
                     /label="sidN_Condensation_DCL.4"
                     /locus_tag="sidN"
                     /protein_end="3957"
                     /protein_start="3677"
                     /score="123.0"
                     /tool="antismash"
                     /translation="AVYPLTPLQAGMISATVMMDPTLYAHHHPFRLPQGTSIDQVRSAW
                     SRLVAKHDILRTSFHEINQPRPQLVGAVHQESILNWHEVATEDVQVAIDDLIKRTQFPS
                     VSSFETPPVKATVIRSPEDMLLVVSLHHATYDGTSIRFIFEDLWAILRGNRVPERNPFY
                     ETAMKIHNMSSGSVGFWADSLSGYGGAAAIAEAEDIQNKMTSKTMLLAQDTSALEQWCT
                     EKGITIQTICQLAVSKAVCAQTKSRDVVLGQVHAARLDINGADKVAGPMLNTVPLRLC"
     aSModule        11032..12567
                     /domains="nrpspksdomains_sidN_Condensation_DCL.4"
                     /domains="nrpspksdomains_sidN_PP-binding.2"
                     /incomplete
                     /locus_tags="sidN"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11407..11472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0024"
                     /evalue="4.00E-03"
                     /label="NRPS-E2"
                     /locus_tag="sidN"
                     /protein_end="3824"
                     /protein_start="3802"
                     /score="10.0"
                     /tool="antismash"
                     /translation="LVVSLHHATYDGTSIRFIFEDL"
     CDS_motif       11773..11865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0025"
                     /evalue="7.80E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="sidN"
                     /protein_end="3955"
                     /protein_start="3924"
                     /score="18.4"
                     /tool="antismash"
                     /translation="DVVLGQVHAARLDINGADKVAGPMLNTVPLR"
     aSDomain        12382..12567
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_PP-binding.2"
                     /evalue="2.70E-08"
                     /label="sidN_PP-binding.2"
                     /locus_tag="sidN"
                     /protein_end="4189"
                     /protein_start="4127"
                     /score="26.1"
                     /tool="antismash"
                     /translation="LRKVLSETTDTPVSSIDAQTSIFSIGVDSIVAIRVAGACRKAHIP
                     LHTMEIMRNAKIGKLCE"
     aSDomain        12787..13584
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sidN_Condensation_DCL.5"
                     /domain_subtype="Condensation_DCL"
                     /evalue="9.80E-36"
                     /label="sidN_Condensation_DCL.5"
                     /locus_tag="sidN"
                     /protein_end="4528"
                     /protein_start="4262"
                     /score="115.2"
                     /tool="antismash"
                     /translation="VFKAENGLDAGRLRDTWISLVQKNDSLRTCFAQVKPTLAVQAILK
                     PDCVDAAKSFTVQQVPENMTMEEYVKSEIHHLSLSPSSLYEPPVRIVLIQGGREGVSVL
                     LRLHHALYDAWSMGILIDELSSLYCGTMQKPCPPLSVSHFAQFTQQKLRGKNEEQFWTE
                     TLGQCDPTILTPKADINTDSKSCNRAFVSFECVDVSMGALKSAARAFGITPQCLIQVAF
                     GRMLSDVTESSSPVFGYYTAGRSAELEGIEALASPTLNMLPVAV"
     CDS_motif       12808..12882
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0026"
                     /evalue="3.30E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="sidN"
                     /protein_end="4294"
                     /protein_start="4269"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LDAGRLRDTWISLVQKNDSLRTCFA"
     CDS_motif       13105..13170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0027"
                     /evalue="3.90E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="sidN"
                     /protein_end="4390"
                     /protein_start="4368"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LHHALYDAWSMGILIDELSSLY"
     CDS_motif       13492..13578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sidN_0028"
                     /evalue="4.30E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="sidN"
                     /protein_end="4526"
                     /protein_start="4497"
                     /score="19.2"
                     /tool="antismash"
                     /translation="VFGYYTAGRSAELEGIEALASPTLNMLPV"
ORIGIN
        1 atggatcaag tagccgtcac ccgctttccc gccttacact gctttgaggg gccgaagcag
       61 agacagtcag taggaagcaa tgcgcgccat catactattc gcggcaacat cgacactcaa
      121 caccagagtc aggatgagac cttgcgtcgc tttgccaatt ttgtatcaag cttggtcggg
      181 gatgatgaga tatcattcga cttcatcatt tctcccagca acggcggatc cgatattgcg
      241 gaatctggca cggcccaagc aaaaaaagac ccaacgcagg cgactagtga ctacaatgga
      301 atcacactgt tgcgcagcac accatttgta gaaagcggtc attctgagtt cggtattatc
      361 attcgccgac agcttcgtaa caatgattcg agtcttttta ctcttgaaaa atccttcgtt
      421 gtcgccgtcg acaagtcaag ctactctgta cgcatttgcc gagatctcgt acctcggccg
      481 cttctgcaat ctatcagtac ctccttgtgc tcctacatgg gttggacaaa cccctctcag
      541 cacagtgaag aagaatcgaa tcaagagctt cagcttcaga ccttgaactt tcagggccag
      601 tcagttttga accatcctcc attgatgact ccgccagatt tcgagagtca actctgcctt
      661 ccaaaacggc ctcaggaata tgcgaagcct ttactgcata acgccttctt ggctcgagtg
      721 agggaaaacc ctggcagaat agcattggac gccttaagct cgacaggcag agcaacctac
      781 acttacaaga gtctggatga tctgtcttcg gacctggcag aaaagattct gcagatcatt
      841 ggtgttgacg cagatcacac ggatcgaaat atcactgttg ctttgagcac ttcggcagaa
      901 ttatacattg cctggttagg cattctcaaa gcaggctgcg tagtatcccc agttcctacg
      961 gattgcccgt cgggactgct ccagcacatg acaggactta ccagttccaa ggtcgtgctt
     1021 ggctctgccg agacactcga gtacttcgac aggatcattg gagactcgtc gactttcacg
     1081 ttcatcaacg tagagacaat tgctcgccaa aactacgagc atttgctgca aaggccgcct
     1141 ccgttggtca acacgtctga gaatgatgtc gcttatattc tgtttaccag tggctctacc
     1201 ggcaaaccga aaggcgttca gataacacac catgctgctg tgtgctcaat tgctgcgaac
     1261 attgcggcat ctccctactc gttcgaatcg gggccatcaa gtatcaggtg gttccaaatg
     1321 gcggcgccaa cgttcgacct atccgtcttg gaaatcttcg tcactttctc catcggtggc
     1381 acaatatgtg cttgcgacag aaccatgatg ctcactgatg ctgagtcagt cattactcag
     1441 ttggaagcaa cgattacaat gaccacgccg actttggcgt ctttactgag gccgagcagg
     1501 atcccaaaac ttcgcgaggt atgggtctgc ggcgaaatgc taaaacgcga ggcttcggag
     1561 ctttttgccc gggatcgtga tccatcagtg gcagacggtg atacaaatct tctcaacgcc
     1621 tatggtccga ctgaagccac catcacctgt acggtagatg cgagagtgtc actgaaacac
     1681 agaggatctc ttataggccc acccttgcct acgtgttcca atatcatact ggactcatcc
     1741 gagccaccca aggctgtacc tctaggcttt gcaggtgaat tagccattgg aggtccgcaa
     1801 ctgagtatcg gctatctcaa aagtcccgaa aaaactgcag ccgcctttgt tgacgtcgag
     1861 ccttacggaa aattgtaccg aacaggagac atggcaaggt tgatcatggg cccagatggc
     1921 actctgcaag tcgagttctt aggaagattg tcgtcggatc aaataaaaat tcttggcagg
     1981 cgagtcgaac taggagaaat tgaggccggg ctgcgaaatc ctctcattgc cgaagtggcg
     2041 gcagtggctc tgaaaccgga agtctctggt ctgccacaag tgcaattgat tgccgtcgta
     2101 acttgtcgga cggaaaaaag cgacagcgat atattggctg cttgccaaga aagagcagaa
     2161 aatgtgttgc aaccacatat gcgcccgtcg atttactacg tgatggacaa gctgccccgt
     2221 ctggcgagtg agaagaccga ccggaaaacc ttggccaagt actgcttatc gccggagaaa
     2281 tcagggctga gacgcttgag aaatggggat gtggatggcc atcgtgaagc aggaagcagc
     2341 tcaatcccaa tgctgcagag tgtaattgag gcagtctcca gtgtcgctat cgtgggatcg
     2401 gacaagatta cgtctgcgac cacactccta tctttaggta ttgacagtct acgttctgtc
     2461 agacttctgc agaatttcag ggagattgga atcgaagggc ttcaagttac ggacatcctt
     2521 acatgccata atcttggtga tctcgacacc aaagctcaac aagcattgaa tcgatccacg
     2581 ccctcgctgg ctaaagcgag aaatttgcag actctactca tcgacttcga gaatcgtcac
     2641 aagaagcagt gtctcagcgc attgggcttc aatgaagata acatagtctc ctttttacca
     2701 gtgaccacgt ctcaggccgt ggcattggct agcttccttc tcactgctga tgcaaacggc
     2761 tttcaagcgg ttccgggtgg gaaagcattc attcagcata cagtttatac tgtgaagccg
     2821 gagctgaatt ctcaaaggat tgttgaatct tggactcgcg tgctgtcacg ttacgacatt
     2881 atgcgctcag tcttcgttga ggtaaacgat gatcttacac cctttgctca gtgtatctta
     2941 tcgcccgatc atgaagcagc tcaaatcaag ccacattttt acagcgcgaa atctgataac
     3001 gaatgcaaag acgtcatcca agcggcccaa aaggcggccg aggagaagat ctcgctttat
     3061 gagccacctc gacgcttatc ggttgtacaa tcacccactc aaactattat agtcttcagc
     3121 cagctacact ccgtctttga tggtggctca gaaactcttc tcttggagga tatcgagaga
     3181 gaatactttg ggcaaccaag catcgagcga actggggttc tgactgccgt tgaaagacat
     3241 ttctcggaga acagagctga agcagctcag ttctggcagg cttacatgga tgggtttctt
     3301 tcgccttctt tcccatgtct tcgcagcacc gttccaggac ccgacgagaa tgtctgtggt
     3361 ggatacagct tcatgtctga tctgtcgctg gagagcctga cgcgtcaagc tgcagccctg
     3421 caatgctccc ctctttctat cttgcaagca gcctgggcac agatcctgtt tacttatacc
     3481 ggtgagcgag atgttgcatt tggaaatact atgtcgggtc gattcacaac ggagctggtc
     3541 aattgttctg cgccggttct cacaatccaa tcaactcgag tgaatttgaa cgaggaaaac
     3601 gacaaacgaa acatcgacat acttctggaa agaacagcac aaaataccgc agctctttcc
     3661 tatttacata cacccataac tggggctcga tacgatacaa ccattgctct ccagatgtac
     3721 ctaaacagtg gcaaaggtga ggcattgtac gagagagtgt gtcatcctgg tatgcaaaac
     3781 gacctagctg tgatgattga agtctatccc gatcgatccg gccttttgga gttcagattg
     3841 acctaccaaa ctgcacttct cgatgatgat gcggcttata ccatgctcgc aaatcttgca
     3901 cgagtcacaa accatatcat gtcttatccc aacgcgaagt atatggaccc ttcagtttgg
     3961 acatctctgc aggggcctgg ccaactcgaa cagatcaacg ggtaccacca cttgggccag
     4021 cagttgttac acgaatgcgt cgccgaattc gcccagaagt caccaaatgc gattgcgcta
     4081 gcattctatg acgacttgag tgtcgatcat cccaaggttc aactgaccta tgcagatcta
     4141 gaagtgaaag caacaagggt tgctgggttt ctgatgagtc agttgcctgc aaaagaaggc
     4201 tcaaaacatg ttgtgcctat tttcatggag aaatgcccgg agttatacat taccttgttg
     4261 ggcatactga aagctggagc tgcttggtgc ccggttgatc cgagctaccc tcctgctcga
     4321 caaatctttc tcattgaaaa gacaactgcg ggaatctgct tcactagcaa atcgaccact
     4381 tctcaactgt cttccattct gcctgcttct ttcaagtcaa tcagtgtatc cgatttactg
     4441 gaagggggct cttgtagcac ttctcggact ttaaaagcat cggagtctgc gagactggac
     4501 aacctctcga tacagagatc agacatcgcc tacgtcatct tcaccagtgg aaccactggc
     4561 acacctaaag gagttcctat ctcacatgag tcagcgagtt tgtccatcga ctcgtatatt
     4621 cagcgtgtca atgtggactt ggacttgaga ggctgtgaag tccggtttct tcagttcgcg
     4681 aattatacct ttgacgcatt tgtgtgtgat gtgtttacag catggagact gggggggacg
     4741 cttgtttctg ccaccagaga catcctcctt ggctcattta tagctttagc caacaaggtc
     4801 ggcgcgacac acacctcgat gacaccgaca tttgccagca ctttgcagcc ccaggacttc
     4861 gaaacgttgc gagtagcaac aatgggaggc gaagtactac cgcagattct agcagacaag
     4921 tggaagtcac gcatgtctct ctgcaacgtg tacgggccag cagaaacggc aatcaacact
     4981 actatcaaca ggctgagcgc agcatcaaga agtgggaaca tcggaactgc cctcccagcc
     5041 gtcaatgcat acgtgatggc atctggatat ccagtgatga agcacatgct gggagagctt
     5101 gtcatatctg gccctcagct ttcgcctggg tactgggaca atgtacacag tagtaacaac
     5161 aggttccggt ggaattcgac tttgcaatgc cgtgtttacc acacaggaga ctacgttaga
     5221 cagcttgccg atggaagctt tgactttgtt ggtcgaaaag atgatctggt caagatcagg
     5281 ggcatgcgtg tagaactcac agagatatcc actgtctgct cagcaggcca cgagtctgtt
     5341 gttcacagtg aagtgttgct ggccaagctt cccggctcca cgcaatcttc tctcatatgc
     5401 ttcgtggact gtgggctgca gaagtcatct gacgtcgata acttctgtat tctgaagaac
     5461 gaggaggcgc aattagtagc acaagccgtg aaaagacacg ctaccgctga gcttccacgg
     5521 cacatggtgc cagacgtttt catgccattg aactgcttgc cccgcaatca atcctccaaa
     5581 gtcaatcgca agcgactatt agaagttatc ggcagagagt ggtctatgca gccgatgtcg
     5641 ccggtcgcgg atgaacaagt tgaccccgca tggtgtatca agcatcgacc tcttcttgaa
     5701 aagattcaag gcgttatcaa aattatgccg acaacattgt cgaggagcac gactctttct
     5761 gagcttggcg ttgattcaat tggagcaatc agactcagtt caagacttaa aaacgatgga
     5821 catgacatat ccgccatcca agtattggat agtgtaacga ttgaggacct catcaatcac
     5881 ctatctgtta agagacaggg cacttcgaat tggaagacac tcttgagcag atatcttgat
     5941 cattggaaac ctttggtatc acgacaccta gcaagagacc cagctcattt ctccctagtt
     6001 cctaccacag ttttccaaga tggaatgcta gtcgaaacat taagggatcc catgctttat
     6061 tgggctagct attcctggcg acttccctcg acagttgaca ttgcaagagt gcgccaagct
     6121 tggcaacatg tcagcaagaa ccacgatatc ttgaaggtta gcttcgttcc tacagcgtac
     6181 tttgagcaag aggagactca atcttctggg ccgtcttcga tgttcataca gttgattgat
     6241 tacaatgcaa gcatgggctg gcaagaaata gtcagcgact caggcgactg gcagcaatct
     6301 atccacgcgt tgtgcgccaa ccttcaaagg acacagcatg agaacaattt ctcgtcccca
     6361 ccatggcgag taactatact ggcacaacaa gaccagagga tcatgaattt gacgatccat
     6421 cattcattat gcgatggaga aatgctacgt agtttgatgc atgacgtggc gtgggcttat
     6481 tcaacagccg agcttcctgt caagcgctgt caggttcagg aggcagttag cagactcgct
     6541 gtacgctaca gtgaaccgga aggacacaag ttttggggcg acatgttaag ccctttggta
     6601 tcgcagacat ctttaggaga tgcaacgtca aatagcccaa aggctgttgt taggaaaatt
     6661 cgtcatcgta ctactgaact gcaagcgaca cgatcgacgt caaagctaac cgggctggcg
     6721 cggaggcttg gggcatcttc gctgagtcct ctatttcgcg tcacgtttgg aatcatgctg
     6781 acggagtatt acgagcaaca gagcgtatta tttggtgaag ttcgttccga gagattattg
     6841 gagtcgcaac ttgtgggtgc catggcgcca ctctcagcaa cttacccagt gccattccgc
     6901 tcatctggaa accttaaaga tatggtccat agccagcaaa ttttggtgat ggatagcatt
     6961 cgatatgggc ccccgcagcc ttcagacgtt cgcaagattc taaaaaagag tcgggatgag
     7021 gctctctact ccgccgtata tgtcttgcgc cagcgatctg aagatgatgg aggcagcctt
     7081 gcgccgtggg aagaattcaa ggacatcttt gaaatattcg ttgaccatga gtttgctctg
     7141 aatgttctcg agggcgcgga tgacacggtc acaatatcat tgtcggtaga tgagaccttg
     7201 atgtcatcaa gtgctcaagc catcttcttg cagcaactgg acgcacttct cattgctttt
     7261 gataaatctg ctcccgaaat ctctctttct ggccttaacg cccatttccc tctagatctt
     7321 ctgtctattg cttcttccaa agtatccgct cagtatacat ccactgttcc tccctcacac
     7381 tacattgaga cttgggcgaa gacgcaccca gagtggaaag ctgttgaggt tgccactgga
     7441 tttcttggaa gtcagaagat tgtgacggag gattggactt acaaaaagct caacgagacg
     7501 gcaaatcaag tcgcgaatct cataatccac gcctctctcc acggcagagc cattgctgtg
     7561 tctctggatc gatccttgat tgcgtttgcg atcatcgttg gcattatgaa atctggcaac
     7621 acttatgtcc caatcgaggc agggctgccg aacgaccgca aatccttcct tctgcgtgac
     7681 agcagggctg ccatggcatt cgtctgtgac aacaattttg acggagttga gctaccacca
     7741 gagacaaagg ttctcgacac caagaatcaa tcattcatag agaatctgtc cactcaggac
     7801 acctcagaca ttctcaataa ttacccagaa aatcttgatg cttacttgct gtatacttca
     7861 ggctccaccg gtgctccgaa aggagtcaga gtcagtcgac acaatttaag ctctttcagt
     7921 gacgcatggg ggaaattgat tggcaatgtt gcgcccaagt ctctggagct tggaggcgtc
     7981 ggaaagttcc tttgcttagc tagcagggct tttgacgtcc atattggcga aatgttcctg
     8041 gcgtggcgtt ttggtctctg tgcggtgact ggtgaacgtt tatcgatgct ggacgaccta
     8101 ccgcgaacct tcagggaact aggtgtaacg cacgcaggca ttgtaccttc actgctagat
     8161 cagactggcc ttgtacctga agatgcgcct catttggtgt atctcggagt gggtggagag
     8221 aaaatgacac cacgaactca gcaaatctgg tcttcctctg accgggtagc tctagttaac
     8281 gtctatggac caacggaggt tacgattgga tgcagtgccg gacgaatctt gccagactcc
     8341 gacacgaggt gtattggaca tccattagga gactcagttg ctcacgtgct ggctcctggt
     8401 tcaaatgaac atgtcaaaaa gggcatggca ggtgagcttg ttatcgaagg cagtctcgtt
     8461 gccaacggat atctgaacag acccgatgcg aaaggtttct gtgatatcaa cggccgaaag
     8521 atgtatagga ccggagacat tgtccgaatg gatgccgaca gctccatcct gttcctgggg
     8581 cgtaaagatg aacaagtcaa ggtccgtggg cagcgattgg agcttggcga agtttctgag
     8641 gttattcgct ctttatcccc gacagacatt gatgtcgtca cgcttcttct caaccatcca
     8701 ggcacatcaa agcaattttt agtctccttt gtagcatcgt ctggtgctgc tgtaagaggg
     8761 gagctgagat ggatcaacga gaactacaag gaaatcaaca acagtttgcg tcaggcttgt
     8821 gaacaaactt tgccggctta catggttcct gattttatca ttcccatttc tttcatacct
     8881 ttgagggaca cttcggcgaa aacggacgca aaagctctgg agcatatgtt tcatacgctt
     8941 tcacttgggg agctctttgg tgaaagctca tcactcgtca ataagccgac gactgcacct
     9001 tcgagagatc tgacctcgat cgaaaagcaa attctcaccg tggtcaaaag tgttgtaggt
     9061 caagatgaca aacgcgacgc aagacctgga agcacattgt ttcaacttgg gttggatagc
     9121 attgcctcag tcaaactctc attcaagttg aaaaagctgg gattcagcac caccgtggca
     9181 cgactattac aaaacccgac gattgaagag ctgggtcgaa tgaagaatgc cctcaaagga
     9241 tctcaccatg cagagccgtc caattcagaa agcataacaa caaggtttga ggaactggag
     9301 aaagaaacga tgaattcttt gaaggaccgt gaaaccacgc acattgagtc tatcaggcct
     9361 tgcatgcctc tacaagaagt acttgtggcg cacacaatga gccacggatc cgaggcagac
     9421 aatgcgtacg tcagccacat gatctttgag ttagatccgg ctgttgtagt tgagcatgta
     9481 aaagctgcat gggctgctgt ggtcaagaat actgagctgc ttcgaacctg cttcatcgat
     9541 agggaaaatg acatcgttca gcttgtcatc aaggagaacc atgcgacccc agtttggaaa
     9601 cacttgagta atgggacaaa tatgttgaag gaggaattgt tgtcttgcaa gaaagaaatc
     9661 gccgacgaca ttgtcacgaa catcgacaag tctccgcccg ttaggttcac tttagcatct
     9721 tgtgatggcg ccgatgagac aaacgagatg tctctattca tgctctcaat ccatcacgca
     9781 ttgtatgaca tggtttccat cgaaatgatt ttccaagact tcgaggttgc ctacacggac
     9841 agcagcttat cacgacgacc gtctactctg ccgttgctag agcacattgc ggcccagcaa
     9901 cagaacgaaa gtaaagccaa gagctactgg accacgttgt ttgatggtta cgatcacaga
     9961 atagagaaaa tttctccaag gacagcgcag actacggcga ggacactaaa tgcaagtctt
    10021 acaaccttgg agagtttgtg ctcgcagaca aacatgacgt tgtcggcgct catccaggga
    10081 gtattcgcat atgtcctagc acggacattg aaacgcccag atttgatctt tggtgtggtt
    10141 ctgtcaggac gatcaataga tgttgagggt atcgacgcga tggccgcgcc atgtatctcg
    10201 acaattcctc aacgactcaa tattggcacc gacggcgaaa caatcgcaga gctcatcacg
    10261 actgttcaag acaggctttt caagtcaatg gaatatcagt atacatcatt gcgttcgttg
    10321 tcaaggtggc tagagatatc tggcccactg ttttctagct tgttctcgtt tacaaaatta
    10381 tcgccaccgg aagactcagg cagctccaag tccaggatat tgaaacccac ggagggtgag
    10441 atgtttcttg attttgagct ggcacttgag tgtgaggcgg atcctggcac agatacggtg
    10501 acattacgaa cacgctccac aatgtttgac aagatggagg agctagatgc attactcgag
    10561 cagatggagt cactggttac ctcttttact cgaggcgaaa ataaggcggt agatggcgac
    10621 tttgggtcca tgctgcatac acgactacta ccaccccatg ggtctctgca ggaggaaagt
    10681 gacgactggt cagtgctgga gcagcagatt cgggatgtgg tcgtcgcgtt ctcgggtgca
    10741 tcgccgaacg aagtgaaaag gacaacccct ttcatcaagt acggcattga ttcaataaca
    10801 accatcaggt tctcaacgtt gcttcggaaa aacgggttct gggtctccgg agcagatgta
    10861 ctcagaaacc caagcgttgc caaattagca acgcacatac aaactacttc ttctttcaac
    10921 gggactgcca aagactccga cgacgaagcg tccgaatcgg ctggtattgg taattggtcc
    10981 aaggccttgc tcgctggcgc cgtctcgacc aaagtactgg acgatgtcgt cgctgtgtat
    11041 ccgttgacac cactccaggc tggcatgatt tcagccacgg tcatgatgga tccaacatta
    11101 tatgctcacc atcatccctt cagattgccc caaggaacga gcatagacca ggttagatca
    11161 gcttggagca gacttgttgc caaacatgat atcctcagaa cttcctttca tgaaattaac
    11221 cagccccgtc cacaacttgt tggcgccgtg catcaagaat cgatattgaa ttggcatgag
    11281 gtagctacag aagatgttca agtcgctatc gatgacctga tcaaacgcac acagttccct
    11341 agcgtctcgt ccttcgaaac tcctcctgta aaggcgacgg tcattcgaag cccagaagac
    11401 atgctgctcg tcgtgtcgtt gcaccacgcc acgtacgacg ggacttcaat tcgcttcata
    11461 tttgaggatc tctgggctat tctacgtgga aaccgtgtac ccgaacgaaa ccctttctac
    11521 gagactgcta tgaaaattca caacatgtct tcgggatctg taggcttctg ggctgatagc
    11581 ctttccggct acggaggggc agcggcaatt gctgaagcgg aggacatcca aaacaagatg
    11641 acgtccaaga ccatgctgct tgctcaggat acttctgcct tggagcaatg gtgtacagag
    11701 aaagggatca ccattcaaac catctgccaa ctggccgtca gcaaagcagt atgcgcgcag
    11761 acgaagtctc gagatgtagt cctaggccaa gttcatgctg caaggctgga tatcaatggc
    11821 gcggacaagg tggctgggcc aatgctcaac accgttcctc tcaggctctg catacacgat
    11881 gattcgttca ccaaccacga ttacctgcgc gatttgcaag ccttccagaa caagtccttg
    11941 gatcatctgc atgcttccct atcggacatc caacggcttt ggcggaaaga gaatggccgt
    12001 gatgggcagc ttttcgaggt actgtttatt ttcagaaagg gtgaagacgc aactgaagct
    12061 cccttctggc agcctttcga gcctgaaggc tccaaagagt ccctccctcc atctcattat
    12121 gaccttgtca ttgaagtcca ccaaaagagt cgtgggggcc tcgaactgga agttcactcg
    12181 agatttgcag atgataccac gagtaatctg atgagtctgc ttgtcgagag ctttgagagc
    12241 atccgaaagc atccagatga gttggccatt agttcccctg gagtgctgtc caaagtgcca
    12301 aaaccaggac tgacgaggga aacaggggcg gtaccgacca gtccctttga ccaaagcgcg
    12361 atcgatcaat ttttagatcc tctaagaaaa gttttgtcag aaaccactga tacgcctgtt
    12421 tccagcatcg atgctcaaac gagcatattc tccatcggtg ttgattccat tgtggcaatt
    12481 cgtgtggcgg gcgcctgccg gaaagctcat attcccttac acactatgga aatcatgcgc
    12541 aatgccaaaa tagggaagct ctgtgaggtg gcatttgcta aatcgggaca agctgctcca
    12601 aacaggtcta cgacagagtc aaatggcgtt gctccactgc ttgatcaaga ggtcaagaag
    12661 gcggcagcgt ctaaactcgg gagagcggaa gcggagatcc aggaaatact accagtgttg
    12721 cccgggcaag aataccactt ggcatgttgg ctcacctcgg gaaagacgct gctcgagccc
    12781 gtttgggttt tcaaagcgga gaacgggttg gacgcgggtc gattacggga cacatggatt
    12841 tctctcgtac agaaaaacga ctcgttgagg acatgcttcg cgcaagtcaa gccaacgctg
    12901 gccgtacagg caatcttgaa accagattgt gtcgatgcag ccaagtcgtt caccgttcag
    12961 caggtaccgg agaacatgac catggaggaa tatgtcaagt cggaaatcca tcacctctcc
    13021 ctcagcccgt cctcgttata tgagcctcca gtccgcattg ttctcatcca aggaggacgt
    13081 gagggcgttt cggttctact taggctccat cacgcgctgt atgatgcttg gagcatgggc
    13141 attctcatcg atgaactttc aagcttgtac tgcggaacca tgcagaaacc ttgtccgcca
    13201 ttgtctgtct ctcactttgc tcagttcacc cagcaaaaac tgcgcggcaa gaatgaagaa
    13261 cagttttgga ccgagacgct gggccagtgc gacccgacca tcctgacacc gaaagctgat
    13321 atcaatacgg attccaagag ttgcaacagg gcattcgtca gcttcgaatg cgtcgatgtc
    13381 agcatgggtg ccctgaagtc tgctgcccgg gcattcggaa tcactccgca atgcctcatt
    13441 caggtcgcat ttgggcgaat gctctcagac gtgacggaat cgagctcccc tgtattcgga
    13501 tactacacgg ctggtcgatc ggctgagctc gaaggtatcg aggctctcgc cagcccgact
    13561 ctcaacatgc tacctgttgc cgtcccgaag gaccttgtcg cgtctcaact tgccgggaca
    13621 agtctgtcga tactactcca gagcttccaa gaccgcacga attctcaatc agactacgaa
    13681 caaagccgtc tgcgagacgt gatcaagtgg gcaccaaaca aaggcgtctc gcccctcttc
    13741 aacgcccact tgaatatcct gtggaacgat gagatcctgc tcaagcccca ggtgtcgaag
    13801 gacacgctgc ttcgaccctg gccccttggc gtgccgtcag actatgcatc ccccacaccc
    13861 ttgtctcggg gcagttccgt cgatggcttg gacacatctt tccttcccac caatgtgttg
    13921 tttgccgacg taggtcccag ccgagagact gccaacctcg ccattggcat tgggtgcgac
    13981 ccgacgctgc gcgacgcaca gggcttggag gaaattgcgc ggatgttttc gggtcatctg
    14041 tcacggcttg ttggaagcag agatttagtc tga
//
