LOCUS       BGC0001252              7958 bp    DNA     linear   PLN 13-NOV-2013
DEFINITION  Alternaria alternata ACRTS2 gene for polyketide synthase, complete
            cds.
ACCESSION   BGC0001252
VERSION     BGC0001252
KEYWORDS    .
SOURCE      Alternaria alternata
  ORGANISM  Alternaria alternata
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
            Pleosporaceae; Alternaria; Alternaria sect. Alternaria; Alternaria
            alternata complex.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 00:17:01
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /db_xref="taxon:5599"
                     /host="Rough lemon"
                     /isolate="HC1"
                     /mol_type="genomic DNA"
                     /note="rough lemon pathotype"
                     /organism="Alternaria alternata"
     gene            1..7958
                     /gene="ACRTS2"
     protocluster    1..7958
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:7958]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..7958
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..7958
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..7958
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001252"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7958
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             join(1..650,715..997,1045..1166,1225..1418,1476..1887,
                     1961..7028,7091..7267,7323..7958)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-430). E-value:
                     6e-138. Score: 452.1. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (546-873). E-value: 2.6e-89.
                     Score: 291.3. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (941-1118). E-value: 3.6e-23.
                     Score: 74.6. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1424-1596). E-value: 1.1e-74.
                     Score: 242.9. Matches aSDomain:
                     nrpspksdomains_ACRTS2_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1817-2127). E-value: 4.6e-95.
                     Score: 310.1. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2151-2326). E-value: 2.5e-47.
                     Score: 153.0. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2436-2506). E-value: 2e-12.
                     Score: 39.1. Matches aSDomain:
                     nrpspksdomains_ACRTS2_PKS_PP.1"
                     /codon_start=1
                     /gene="ACRTS2"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 210.3; E-value:
                     8.2e-64)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase"
                     /protein_id="BAN19720.1"
                     /sec_met_domain="PP-binding (E-value: 1.7e-08, bitscore:
                     21.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.7e-91, bitscore: 291.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.2e-142, bitscore:
                     461.7, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1e-40, bitscore:
                     125.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 6.8e-11, bitscore: 28.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-14, bitscore:
                     40.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEKDTPVAIIGVSYRAPGIGGKGLWDYLAEAKSAWTKVPPERFEH
                     FAWYKAGEKKTGVFANEGAHFVDNVFDFDAAFFNMRADEARCADPSHRFMLEVALEAAE
                     NAGQSLLDLSGKKIGVFVGAGQHEYSHRVSDDEYAIQTFTATGVAPCMAANRLSYFFDI
                     DGPSVVLDAACASSAYAVDMAVKAIRNGDCDGAFVGAAALNLSPSGWLVLDQSGTLSDI
                     GRSFSYDAKASGFGRGEGAACLLIKRLEDAIRDGDPIQALIRGTACSHSGRSEGITMPS
                     RRAQEKLIWDVHNSAGLDPSNTAVVEVFSRGHGTGTAVGDPIEAGAFTSVLARNRTAAN
                     PIYIGSLKSNFGHLEGASGVLAMIKAVLMVRNGVVLPTAGFERINEAIDNYEKIKVPTT
                     PLPWPENEPRRCLVTNFGFGGSSSAVIIDRSPYLHALDGYEDLADIKIPRLNGSSGRSE
                     SGSGQSQRLFVFSAKTRDSLTAYLASFHEYLLKAQESHEFLKDLSYTLGQRRTHHAYRA
                     SVVANSISDLRKEIPNLKPSKIRQRSVIFVFTGQGAQYARMAYNLRQFTVFAETLEKAE
                     TQLNKMGASWSLTEELNKLTDTRINDAEISQPACTAVQLAMVALLQSWGVVPNMVTGHS
                     SGEIAAAFTAGLLTFQEAIAISYFRGQSAVQLSAAQHEYKKGAMLALGVGSEDALKIID
                     EHAQGYATVAAINSPRSVTISGDKTAIENVRKAADMQGLFARMLKVEVAYHSRHMEQVA
                     ASYLKDIEPYFQGKAIPAENSGACRPVFVSSVTGQIIDAVDSSYWIKNLVQPVLFADAI
                     KEVLTHEDQGKSQSIHGSSKTLVEIGPHAALKNPVKQTAELLSSERAWNLASLNYLPSL
                     LRGTNDVHAILELARALFDLGASVELSGVNGTNKHNARVLTELPSYAWDRSYYELRPRV
                     THDKQFPGEEYHALIGRKAPSNAAQENTYRQVFTLDEMPWIRDHVVSGVTVFPMTGYMS
                     CAIEAARRVDSAAPAAFLITDFHVVQSLEIHEEETVDLTTKLKPAATGEGTFSSKVWSF
                     EVVSWSEANGWTRHCWGKIEPEIADLTLATPTFEASLPLVTSMAGVIEHDMDNEYHNIE
                     LRGTKYGPSFRNNVKFYEGKNYTVLEHRIRDLGDALKIPVYRGSPVSVDPPTLDSFLQG
                     AGPFQYDGSGRRLTQMPDYISRFRISNNITSEPNHRLDVVMRRLDYDDKGGRMHVSVAV
                     FGRGSDDQFTPIAEWESFTFRTVSSADDQSASVPDNWSWELLPRYDLISKDTLRDRLLE
                     SVGDLGEEEDVRMSKLDAVGCYYIEKALKDTVTLDYSKLPTHLARFVHWGRNVLKEYEV
                     NFESEPTSLLEDVRNLDAQGELLCLMGENLVDILAGRIEPLEVMLTDGRLMRHYEADVA
                     NAHLSKIIGYLTENMADLEPWQRILEIGGGTAGTTLPVLEGLSRNRDEPGCLDYTFTDI
                     SSGFFEMASKKLSRWSQQITYKRLDITQDPAMQGFTQESYDVVVAANVLHATADMVTTM
                     THVRSLLKPGGKLILLEATRHPPWLLPFTLLPDWWAAKDKYRDHKQGPMMPAVVWNDLL
                     LDSGFSGVDVVIPTNYRTDNPLMNVVCSTRIGKQDDSETITICGPLVDDTEVNFAQSVA
                     RSISKELGCPTEIKRFADIKPDDESYYILLDSKHESVFQNFNPGKFECLKSLLLRNKGL
                     LWVTAKGCSPDAKMIQGMVRTVRLEVEPKNLMLLDNVPSTPEGLSGILKLAARLRDPEV
                     SRDQDMDFAWHDGAIHLPRMRQLKDLKEQFSVEEGVAFRRTQNLRDNSDRGLEMTIQAA
                     GSPDTIYFRRTDPYEVSEDEVLVRVEAAGVGHRDFEVLMGSIPWAPPGYEGAGKVLKIG
                     SQVSHLREGDDVFFLTPEASAFATEVKLASWLVARIPKNMTVTDAAACPLGYCLATLAF
                     RTARLTKNETVLIHSAASSVGQACILLAQDIGARIYVTAGTEDKRDYLHQALGIPRDHI
                     FSSRTAEFRDSLLCKTNNRGVDVVVNSLSGELLTETWAVIAAFGRFVEIGKKDAFLNNS
                     LPMRPFNNNVTLSAIDLRDLYHHRPDDVRSVWNEVVNLLQRKQVRPVDSASVVSISHFS
                     AALRILRSRDHIGRLVVTLGDDNSVMAETALRPSQVSLKDDATYLVAGGTRGIGLDLAY
                     WMIEHGARNIVLLGRSGASGPEAQKILNKFRNTKVCVRAVACNVGDRDELQNALESIKD
                     LPAIRGVVHSALLLSDKLFVNASYEDWVINTTPRVAGAWNLDDLLPTDLDFFVALSSFN
                     GDTGHTGQAIYAGTAGFYNAFSQYRNNRGQYTVSIGLPVVLDVGYVADHDLRGGLLNDS
                     LSAGVTMADIRATFNCILLGPSSPFVRNGRASTFKVYINGQPVQDVTWNYFHPAHSKVR
                     LTNANRNKVKATSGGAEISSASWTTAEDPLTGLIEALIAKVSAMTMMEREDVLPDAPLA
                     SYSLDSLVSVELRNWIRRETTAEMTLVSITKAENLRALAVNILAQRKAG"
     aSDomain        join(19..650,715..997,1045..1166,1225..1418,1476..1516)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.00E-138"
                     /label="ACRTS2_PKS_KS.1"
                     /locus_tag="ACRTS2"
                     /protein_end="430"
                     /protein_start="6"
                     /score="452.1"
                     /tool="antismash"
                     /translation="VAIIGVSYRAPGIGGKGLWDYLAEAKSAWTKVPPERFEHFAWYKA
                     GEKKTGVFANEGAHFVDNVFDFDAAFFNMRADEARCADPSHRFMLEVALEAAENAGQSL
                     LDLSGKKIGVFVGAGQHEYSHRVSDDEYAIQTFTATGVAPCMAANRLSYFFDIDGPSVV
                     LDAACASSAYAVDMAVKAIRNGDCDGAFVGAAALNLSPSGWLVLDQSGTLSDIGRSFSY
                     DAKASGFGRGEGAACLLIKRLEDAIRDGDPIQALIRGTACSHSGRSEGITMPSRRAQEK
                     LIWDVHNSAGLDPSNTAVVEVFSRGHGTGTAVGDPIEAGAFTSVLARNRTAANPIYIGS
                     LKSNFGHLEGASGVLAMIKAVLMVRNGVVLPTAGFERINEAIDNYEKIKVPTTPLPWPE
                     NEPRRCLVTNFGFGGSSSAVIIDRS"
     aSModule        19..7934
                     /complete
                     /domains="nrpspksdomains_ACRTS2_PKS_KS.1"
                     /domains="nrpspksdomains_ACRTS2_PKS_AT.1"
                     /domains="nrpspksdomains_ACRTS2_PKS_DH.1"
                     /domains="nrpspksdomains_ACRTS2_cMT.1"
                     /domains="nrpspksdomains_ACRTS2_PKS_ER.1"
                     /domains="nrpspksdomains_ACRTS2_PKS_KR.1"
                     /domains="nrpspksdomains_ACRTS2_PKS_PP.1"
                     /iterative
                     /locus_tags="ACRTS2"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       493..540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0001"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="ACRTS2"
                     /protein_end="180"
                     /protein_start="164"
                     /score="11.4"
                     /tool="antismash"
                     /translation="GPSVVLDAACASSAYA"
     CDS_motif       join(1859..1887,1961..1985)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0002"
                     /evalue="2.40E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ACRTS2"
                     /protein_end="562"
                     /protein_start="544"
                     /score="13.8"
                     /tool="antismash"
                     /translation="IFVFTGQGAQYARMAYNL"
     aSDomain        join(1865..1887,1961..2918)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_AT.1"
                     /evalue="2.60E-89"
                     /label="ACRTS2_PKS_AT.1"
                     /locus_tag="ACRTS2"
                     /protein_end="873"
                     /protein_start="546"
                     /score="291.3"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQYARMAYNLRQFTVFAETLEKAETQLNKMGASWSLTEE
                     LNKLTDTRINDAEISQPACTAVQLAMVALLQSWGVVPNMVTGHSSGEIAAAFTAGLLTF
                     QEAIAISYFRGQSAVQLSAAQHEYKKGAMLALGVGSEDALKIIDEHAQGYATVAAINSP
                     RSVTISGDKTAIENVRKAADMQGLFARMLKVEVAYHSRHMEQVAASYLKDIEPYFQGKA
                     IPAENSGACRPVFVSSVTGQIIDAVDSSYWIKNLVQPVLFADAIKEVLTHEDQGKSQSI
                     HGSSKTLVEIGPHAALKNPVKQTAELLSSERAWNLASLNYLPSLLR"
     CDS_motif       2172..2285
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0003"
                     /evalue="2.00E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ACRTS2"
                     /protein_end="662"
                     /protein_start="624"
                     /score="32.7"
                     /tool="antismash"
                     /translation="GVVPNMVTGHSSGEIAAAFTAGLLTFQEAIAISYFRGQ"
     CDS_motif       2679..2723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0004"
                     /evalue="2.30E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ACRTS2"
                     /protein_end="808"
                     /protein_start="793"
                     /score="10.6"
                     /tool="antismash"
                     /translation="DSSYWIKNLVQPVLF"
     aSDomain        3123..3653
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_DH.1"
                     /evalue="3.60E-23"
                     /label="ACRTS2_PKS_DH.1"
                     /locus_tag="ACRTS2"
                     /protein_end="1118"
                     /protein_start="941"
                     /score="74.6"
                     /tool="antismash"
                     /translation="HALIGRKAPSNAAQENTYRQVFTLDEMPWIRDHVVSGVTVFPMTG
                     YMSCAIEAARRVDSAAPAAFLITDFHVVQSLEIHEEETVDLTTKLKPAATGEGTFSSKV
                     WSFEVVSWSEANGWTRHCWGKIEPEIADLTLATPTFEASLPLVTSMAGVIEHDMDNEYH
                     NIELRGTKYGPSFR"
     CDS_motif       3207..3284
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0005"
                     /evalue="4.60E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="ACRTS2"
                     /protein_end="995"
                     /protein_start="969"
                     /score="28.8"
                     /tool="antismash"
                     /translation="WIRDHVVSGVTVFPMTGYMSCAIEAA"
     aSDomain        4572..5087
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="1.10E-74"
                     /label="ACRTS2_cMT.1"
                     /locus_tag="ACRTS2"
                     /protein_end="1596"
                     /protein_start="1424"
                     /score="242.9"
                     /tool="antismash"
                     /translation="RILEIGGGTAGTTLPVLEGLSRNRDEPGCLDYTFTDISSGFFEMA
                     SKKLSRWSQQITYKRLDITQDPAMQGFTQESYDVVVAANVLHATADMVTTMTHVRSLLK
                     PGGKLILLEATRHPPWLLPFTLLPDWWAAKDKYRDHKQGPMMPAVVWNDLLLDSGFSGV
                     DVVIPTNYR"
     aSDomain        5751..6680
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_ER.1"
                     /evalue="4.60E-95"
                     /label="ACRTS2_PKS_ER.1"
                     /locus_tag="ACRTS2"
                     /protein_end="2127"
                     /protein_start="1817"
                     /score="310.1"
                     /tool="antismash"
                     /translation="PDTIYFRRTDPYEVSEDEVLVRVEAAGVGHRDFEVLMGSIPWAPP
                     GYEGAGKVLKIGSQVSHLREGDDVFFLTPEASAFATEVKLASWLVARIPKNMTVTDAAA
                     CPLGYCLATLAFRTARLTKNETVLIHSAASSVGQACILLAQDIGARIYVTAGTEDKRDY
                     LHQALGIPRDHIFSSRTAEFRDSLLCKTNNRGVDVVVNSLSGELLTETWAVIAAFGRFV
                     EIGKKDAFLNNSLPMRPFNNNVTLSAIDLRDLYHHRPDDVRSVWNEVVNLLQRKQVRPV
                     DSASVVSISHFSAALRILRSRDHIGRLVV"
     CDS_motif       6120..6182
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0006"
                     /evalue="2.10E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="ACRTS2"
                     /protein_end="1961"
                     /protein_start="1940"
                     /score="26.5"
                     /tool="antismash"
                     /translation="NETVLIHSAASSVGQACILLA"
     CDS_motif       6192..6242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0007"
                     /evalue="5.70E-06"
                     /label="PKSI-ER_m6"
                     /locus_tag="ACRTS2"
                     /protein_end="1981"
                     /protein_start="1964"
                     /score="18.9"
                     /tool="antismash"
                     /translation="GARIYVTAGTEDKRDYL"
     CDS_motif       6321..6359
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0008"
                     /evalue="8.30E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="ACRTS2"
                     /protein_end="2020"
                     /protein_start="2007"
                     /score="12.1"
                     /tool="antismash"
                     /translation="TNNRGVDVVVNSL"
     CDS_motif       6405..6434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0009"
                     /evalue="6.40E-03"
                     /label="PKSI-ER_m8"
                     /locus_tag="ACRTS2"
                     /protein_end="2045"
                     /protein_start="2035"
                     /score="10.0"
                     /tool="antismash"
                     /translation="GRFVEIGKKD"
     aSDomain        join(6753..7028,7091..7267,7323..7394)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_KR.1"
                     /evalue="2.50E-47"
                     /label="ACRTS2_PKS_KR.1"
                     /locus_tag="ACRTS2"
                     /protein_end="2326"
                     /protein_start="2151"
                     /score="153.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ATYLVAGGTRGIGLDLAYWMIEHGARNIVLLGRSGASGPEAQKIL
                     NKFRNTKVCVRAVACNVGDRDELQNALESIKDLPAIRGVVHSALLLSDKLFVNASYEDW
                     VINTTPRVAGAWNLDDLLPTDLDFFVALSSFNGDTGHTGQAIYAGTAGFYNAFSQYRNN
                     RGQYTVSIGLPV"
     CDS_motif       6756..6854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0010"
                     /evalue="4.50E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="ACRTS2"
                     /protein_end="2185"
                     /protein_start="2152"
                     /score="51.3"
                     /tool="antismash"
                     /translation="TYLVAGGTRGIGLDLAYWMIEHGARNIVLLGRS"
     CDS_motif       join(7190..7267,7323..7352)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACRTS2_0011"
                     /evalue="2.00E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="ACRTS2"
                     /protein_end="2312"
                     /protein_start="2276"
                     /score="20.3"
                     /tool="antismash"
                     /translation="LDFFVALSSFNGDTGHTGQAIYAGTAGFYNAFSQYR"
     aSDomain        7725..7934
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACRTS2_PKS_PP.1"
                     /evalue="2.00E-12"
                     /label="ACRTS2_PKS_PP.1"
                     /locus_tag="ACRTS2"
                     /protein_end="2506"
                     /protein_start="2436"
                     /score="39.1"
                     /tool="antismash"
                     /translation="GLIEALIAKVSAMTMMEREDVLPDAPLASYSLDSLVSVELRNWIR
                     RETTAEMTLVSITKAENLRALAVNI"
ORIGIN
        1 atggaaaagg atactccagt cgctattatc ggagtctcct accgtgctcc tggcatcggt
       61 ggtaaagggc tatgggatta tctggcggaa gctaaatctg cctggacgaa agttccaccc
      121 gagcgcttcg agcattttgc gtggtacaaa gctggtgaaa agaagactgg cgtattcgca
      181 aatgaaggag ctcacttcgt cgacaacgtc ttcgactttg atgctgcttt tttcaatatg
      241 agagctgatg aagctaggtg tgcagaccca agtcaccgtt ttatgcttga agtggctttg
      301 gaagctgctg agaatgcggg tcaaagcctt cttgacctgt ctggtaaaaa gatcggtgtg
      361 tttgtcgggg ctgggcagca tgagtactcg caccgtgtta gtgacgacga atacgccatc
      421 caaactttta cagccaccgg tgttgctccc tgtatggcag ctaatcgtct ctcttacttc
      481 ttcgacatcg atggtccgag tgttgtactt gacgctgcgt gcgcgagcag cgcgtatgcg
      541 gttgatatgg ctgtcaaagc catacggaat ggtgattgcg acggcgcttt tgtcggagct
      601 gcagcactta atttgagccc atcgggatgg ctcgtcctcg accaatctgg gtaaccacac
      661 cataaacccg tgaattggtc actgtatctg acatgaacta atatctcatt gtagaacatt
      721 atcagatatt ggaagaagtt tttcatatga tgccaaagcg tctggatttg gtcgtggtga
      781 aggcgctgcc tgtttgttaa tcaagcgcct ggaagacgct attcgtgacg gcgatccaat
      841 ccaagcattg atccgaggca ctgcctgcag ccatagcggc agatccgaag gtatcaccat
      901 gcctagccgc agagctcaag agaaactaat ctgggatgtg cataattccg ctggattgga
      961 tccgtcgaat acagctgtcg ttgaggtatt ttcccgggtc cgttggagac ttgaagacga
     1021 tcgctgacct actcaacaat atagggccat ggcactggca cggctgttgg agacccgata
     1081 gaagccgggg ctttcacatc tgtcctcgcg agaaaccgaa cagcagctaa tcccatctat
     1141 ataggttctc ttaaatccaa cttcgggtaa gaagaaaacg tctcgcttga tgcggataac
     1201 tgactgacat gaactcctgc gtagacatct agaaggcgca agtggcgttc tcgcaatgat
     1261 caaggcagtg ttgatggtca gaaacggtgt tgtccttcct accgccggct tcgagagaat
     1321 caatgaagct atcgacaact acgaaaagat aaaagttccc acaacgccac ttccttggcc
     1381 agagaacgag ccaagacgct gcctcgtgac caattttggt gggtgcaaag aagtttgcgt
     1441 tataatatga aaatcaacta atcggagctg ctcaggcttt ggcggaagca gttcagctgt
     1501 tatcatcgat cgatctccat atctgcatgc attagacggg tacgaagacc tcgcagatat
     1561 caagattcca agactaaacg gctccagtgg ccgcagtgaa agcggttctg gtcaaagtca
     1621 gcgactcttc gtgttttcgg caaaaacgcg agatagtctt accgcttacc tagcttcttt
     1681 ccacgaatac ttactgaagg cacaggaatc acatgaattt ctaaaagatt tgagctacac
     1741 acttgggcaa cgccgtacgc atcacgcata tcgagcttct gttgttgcaa attccataag
     1801 cgatcttcgc aaggagattc cgaacctgaa gcccagcaag ataaggcaac gatctgtcat
     1861 tttcgtcttt acaggacagg gcgcgcagta agtttacgat ttctggcaaa agttgctgtt
     1921 tgaaataccg tggacaacta acagtgccgc tcaacgatag atatgcgcgg atggcgtaca
     1981 acttgaggca gttcacagtt tttgctgaga ccttggaaaa ggcagaaacc cagctcaaca
     2041 agatgggagc gagctggtct ttgactgaag agctaaacaa attgactgat actcgcatca
     2101 atgatgctga gatcagccag ccggcctgca cagcagtgca attagcaatg gtggcactgc
     2161 tccaaagctg gggcgttgtt cccaacatgg taactggaca ttccagcggt gagatcgccg
     2221 cagcctttac agctggactg cttactttcc aagaagcgat agccatatcg tatttccgtg
     2281 gtcagtccgc tgttcaactg tccgcagcgc agcacgagta caagaaggga gctatgttgg
     2341 ctcttggtgt gggttcggaa gatgctttaa agattattga cgagcacgcc caaggttatg
     2401 caaccgtcgc tgctatcaat agcccacgaa gtgtcactat ttcaggagac aaaaccgcga
     2461 tcgaaaacgt acgcaaggcg gcagatatgc agggcttgtt cgctcgtatg ctgaaggtgg
     2521 aggtagcata ccattctcgt cacatggaac aggtcgccgc ctcctaccta aaggatatcg
     2581 agccttattt ccaggggaag gctattccag ccgaaaatag tggcgcctgt cgcccggtgt
     2641 ttgtgtcttc tgttactggg cagatcatag acgcggttga ctcatcctat tggattaaaa
     2701 acttggttca gcctgttttg ttcgcggatg ctatcaagga agttctcact cacgaagatc
     2761 aaggcaagag ccaatctatt catgggtcat ccaagactct tgtagaaatt gggccccatg
     2821 ccgccttgaa gaaccctgtt aaacaaactg cggaacttct gtcgtctgaa agagcctgga
     2881 atctggcatc gctcaactac ttgccctctt tactgcgtgg taccaacgac gttcacgcta
     2941 ttcttgagtt ggctcgagct ctattcgatc ttggagccag tgttgaactg agtggtgtaa
     3001 acggtaccaa caaacataat gccagagttc taactgaact tcctagttat gcgtgggata
     3061 gatcctacta tgagcttcga ccgcgcgtca cgcatgacaa gcaatttcct ggtgaggagt
     3121 atcatgccct catagggagg aaagctccat cgaatgcagc tcaggagaac acttacagac
     3181 aggtcttcac tctagacgag atgccgtgga ttcgagacca cgtcgtgtct ggagtcaccg
     3241 ttttcccaat gactggttac atgtcatgcg ctatagaggc tgctcggagg gtagacagcg
     3301 ctgccccagc tgcttttctc ataacagatt ttcatgttgt ccagagtctg gagatccatg
     3361 aagaagaaac tgttgacttg acgaccaagc ttaagcccgc agcaactggg gaagggactt
     3421 tttcttcaaa agtgtggtct ttcgaagttg tatcgtggtc agaggcgaac ggatggactc
     3481 gacattgctg gggaaagatt gagcctgaga ttgccgacct gacgttagca acccctacct
     3541 ttgaagcttc gttgccgctt gttacctcta tggcgggtgt gattgagcac gatatggaca
     3601 acgagtacca caacatcgag ttaagaggta ctaagtacgg accgtcattt cgaaacaacg
     3661 taaagtttta cgaagggaag aattatacag tacttgaaca caggattagg gatctgggcg
     3721 acgcactcaa aatcccggta tatcgtggat cacccgtcag cgttgatcct ccaactctgg
     3781 acagctttct ccagggtgcg ggacctttcc agtatgacgg aagcggcagg aggctgacac
     3841 agatgcctga ttatatcagc cgattccgga tatccaacaa cattacatct gaacctaacc
     3901 accgcctgga tgtggtcatg cgccgactcg actacgatga caagggaggt cgcatgcatg
     3961 tcagcgttgc tgtatttggg agaggttccg atgaccagtt tactcccatt gcggaatggg
     4021 agtcattcac gtttcgaact gtcagctccg ctgatgatca atcagcgtcc gttcctgaca
     4081 attggtcctg ggaactgctc ccacgttacg atctaatctc caaagacact ttaagagaca
     4141 ggctcctcga gtctgtcgga gatctggggg aagaagaaga tgttcgtatg agcaagcttg
     4201 acgcggtggg ttgttactat atcgagaagg cgctcaagga cacagtcacc ctcgactatt
     4261 cgaagctccc aacgcatcta gcacggtttg tccattgggg ccgcaacgtc ttgaaagaat
     4321 acgaagtgaa ctttgagagc gagcccacgt cccttctgga ggatgtccga aaccttgatg
     4381 ctcagggaga actcctctgt ctcatgggcg aaaatttggt tgacattttg gctggtcgga
     4441 tcgagcctct tgaagtcatg cttaccgatg gccgtttgat gcgacactat gaggcagacg
     4501 tggcgaatgc tcacctcagc aagatcatcg gttatctaac tgagaacatg gccgatttgg
     4561 aaccatggca acgcatctta gagatcggag gcggaacggc tggcaccaca cttccagtat
     4621 tggaaggcct gtctcgcaat agagatgagc ccggatgtct tgactacacc ttcacagata
     4681 tctcatccgg attttttgaa atggctagca agaagctaag cagatggtca caacaaatca
     4741 cgtataagag gctcgatatc acccaggatc cagccatgca gggcttcacc caggagtcat
     4801 atgatgtcgt tgtagcagca aacgtgttgc atgctactgc agacatggta acgacaatga
     4861 cgcacgtacg gagtctactg aagccggggg gcaagctcat cttgctggag gcgacccggc
     4921 atccaccctg gttgcttcct ttcacattac taccggactg gtgggcagcc aaagacaagt
     4981 accgcgacca taaacaggga ccaatgatgc ctgcagttgt ttggaacgac ctgcttctgg
     5041 atagcggatt ttctggagtc gacgttgtca ttccgactaa ttaccgcacc gacaacccac
     5101 taatgaacgt cgtttgctca acaagaattg gcaagcagga cgacagcgaa acgattacca
     5161 tatgtggacc acttgtcgac gatacagaag tgaactttgc ccaatcagtt gctcgttcga
     5221 tttcaaaaga acttggctgt ccaactgaga tcaaacgatt cgccgacatc aagccagacg
     5281 atgaatcgta ttacattctc cttgattcga aacatgagtc tgtcttccaa aatttcaatc
     5341 ccggaaagtt tgaatgcttg aagagcttgc tcttacgcaa caagggactc ctatgggtaa
     5401 cagccaaagg ctgttcgccc gacgccaaaa tgattcaggg catggtgcgt acagttcgtt
     5461 tagaagttga gccgaaaaac ctgatgctgc tcgataatgt accaagcaca cctgagggtc
     5521 tgtcggggat tctcaaactg gccgcaaggt tgagagatcc tgaagtatcg cgcgatcagg
     5581 atatggattt tgcctggcat gatggtgcga tacacctacc tcgcatgcgg caattgaagg
     5641 acctgaagga acaattttct gttgaggaag gagttgcctt ccgaagaaca cagaatcttc
     5701 gggacaacag cgatcgcggt ttagagatga caatccaagc agctggcagc cctgacacca
     5761 tttacttccg gaggacggat ccatatgagg ttagtgagga tgaagttctc gttagagtcg
     5821 aggccgcagg tgtcggacac cgcgatttcg aagtgttgat gggttccatt ccgtgggccc
     5881 ctcctggata cgaaggagcc ggcaaggtcc tgaagatcgg ctcccaggtg tcccatttac
     5941 gagagggcga cgatgtcttt tttctcacac ctgaagctag tgcttttgcg accgaagtca
     6001 aactcgcctc gtggctcgtt gcaagaatcc cgaagaacat gactgtcaca gatgcggcag
     6061 cctgtccgct aggatactgt cttgcgactc tggcatttcg tacagcacgg ctcacgaaaa
     6121 acgagactgt actcattcac tctgcagcca gctctgttgg tcaggcgtgt atcttgcttg
     6181 ctcaagacat tggagctcgc atatatgtca ctgccggaac tgaggacaag agagactatc
     6241 tgcaccaggc tttgggtata cctcgggacc acatcttctc cagtcgtaca gcagagttca
     6301 gggacagcct gttgtgtaag acgaacaaca gaggcgtaga cgtcgttgtg aactcgctta
     6361 gcggtgaact cctgacagaa acatgggccg tgatcgctgc cttcggtcga tttgttgaaa
     6421 taggcaagaa ggacgctttc ctgaataaca gcctacctat gaggcccttc aacaacaatg
     6481 tgactttgag cgctattgat ttacgggatc tatatcatca tcgaccggat gacgtcagga
     6541 gtgtctggaa tgaagtggtc aacctactgc aacgcaagca ggtacggcct gttgattcgg
     6601 cgtctgtagt atccatctcc catttctctg cggcacttcg gattttgaga tctcgcgatc
     6661 acattggcag gctagttgtg acactgggag acgacaacag cgtcatggcc gaaactgcgc
     6721 ttcgaccttc gcaagtcagt ctgaaagatg acgcgacata cttggtcgct ggaggaaccc
     6781 gcggcattgg gctggacttg gcttattgga tgatcgaaca cggagcccgt aacatcgttc
     6841 ttctgggccg tagcggtgct tctggacccg aggcgcagaa gattttgaac aaattccgga
     6901 atactaaggt gtgtgtgagg gctgtcgcat gcaatgtcgg cgatcgcgac gagcttcaaa
     6961 atgcattgga gtcgataaaa gatcttcccg ctatccgggg cgtggtgcac agtgctctac
     7021 tactcagtgt aagtccaaag tagaagacga ctaattcaca gacgtaggga tgctgaccaa
     7081 cgcgtcttag gacaaactct ttgtgaatgc ctcttatgag gattgggtca tcaacactac
     7141 gcccagagtg gcgggcgcat ggaatcttga cgatttgctg ccaacagatc tcgacttctt
     7201 tgtggctcta tcctcattca acggagatac tggccacacg ggccaggcaa tatacgcagg
     7261 cactgcagta agcctattca caattttgtg agacgccctt gtaggagcta acatctagaa
     7321 agggattcta caacgcattt tcccaatacc ggaacaaccg cggccaatac actgtttcta
     7381 ttggcttgcc cgttgttctt gacgtgggat atgtggcgga ccacgacctt cgaggaggcc
     7441 ttttgaacga ctctcttagt gctggtgtca cgatggctga catacgcgcg acgttcaatt
     7501 gcattcttct tgggccatcg tcacctttcg tccgcaatgg cagagcttca actttcaagg
     7561 tctacatcaa tggacagcca gttcaggatg tgacttggaa ttactttcat ccagcgcata
     7621 gcaaggtacg cctcaccaat gcaaatcgga acaaggtgaa agctaccagc ggtggcgctg
     7681 aaattagctc ggcctcatgg accactgcgg aagacccttt gactggcctg attgaggcgc
     7741 ttattgcaaa agtttctgct atgaccatga tggagcggga agatgtgttg cccgatgctc
     7801 ccctagcgtc ttacagccta gattccttgg tgtctgtcga gttacgcaat tggatacggc
     7861 gagaaactac tgctgagatg acgttggttt cgatcacgaa ggctgagaat ttgcgagcgc
     7921 tcgcagtcaa tattctagcc cagaggaagg cagggtaa
//
