LOCUS       BGC0001262             32353 bp    DNA     linear   PLN 27-MAY-2014
DEFINITION  Alternaria alternata AKT gene cluster, involved in AK-toxin
            production.
ACCESSION   BGC0001262
VERSION     BGC0001262
KEYWORDS    .
SOURCE      Alternaria alternata
  ORGANISM  Alternaria alternata
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
            Pleosporaceae; Alternaria; Alternaria sect. Alternaria; Alternaria
            alternata complex.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 15:13:10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 32353
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..32353
                     /db_xref="taxon:5599"
                     /mol_type="genomic DNA"
                     /organism="Alternaria alternata"
                     /strain="15A"
     subregion       1..32353
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..32353
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1987..>10011)
                     /gene="AFT9h"
                     /pseudogene="unknown"
     CDS             complement(1987..>10011)
                     /codon_start=1
                     /gene="AFT9h"
                     /note="polyketide synthase"
                     /pseudogene="unknown"
                     /transl_table=11
                     /translation="MNGYRANVIHCH"
     gene            16612..17460
                     /gene="AKT2-1"
     CDS             join(16612..16661,16722..17460)
                     /codon_start=1
                     /gene="AKT2-1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in AK-toxin production"
                     /product="esterase/lipase family protein"
                     /protein_id="BAO10614.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-12, bitscore:
                     36.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQPIIGVGHSMGGCQIATLSVTSRRMFSTMILLDPAIGPPDMGL
                     ATLDLGQLTLRRRTQWPTREDAEKALRTSFSTWDSQVLNLLIKHSIHSDKQSIEMEDGP
                     VSLVTGRYQELVNYIKPSFIRSGKVNGQELIHQTGPVDMYHMLGLVTCSALYLCGGEST
                     LSVPRVRDLWLNRTAKLSYSKEPGETRKVDERIVPDTGHFLPMEEPKKCADIIADWIEK
                     DKCIAWNCCVGKRGKTWCELSNASKEMSAEAWMKYLQSKL"
     gene            19365..20699
                     /gene="AKTR-3"
     CDS             19365..20699
                     /codon_start=1
                     /gene="AKTR-3"
                     /note="involved in AK-toxin production"
                     /product="Zn(II)2Cys6 transcription factor"
                     /protein_id="BAO10615.1"
                     /transl_table=11
                     /translation="MLQCAPKKNERLRGSCDFCTQSKLRCNKNKPSCRRCTIQQQPCVY
                     SVARRTGRPPKHPRTANDCQEANGQHGEQDPVTSTPGGSCQQQSNHLLDVEGDGANFTL
                     ADASTTAQGRETPASSALDNALLVGETFGFSSLLDDPLIQSDDFLSFSLCMPPGEEEGH
                     MASPRALNGSTGPCSPTVLSSIDVPHLPARFGFLESSVESGLHGRTGPHLVEQPDKIVP
                     SSFSEMEKIYDEGLTFSGLDSAINAVTNNGKGEPSASGTMAAHPHSKRQCFCSTSMSKL
                     QMLISHPTLCQKNSRARFDMTLFLEEVVFNIHRDVLQCLVCQSKSLHSLASLCICTDWV
                     IEALRDVAQDLSSGQDNLGGFRAGLCPPKDKFSICVGRFVLDDQLRESCTRSLVKYRLR
                     KLVPIMDTMMKLNYRGAGGALSQAIRTMVEDVRHKIESALGMMEL"
     gene            22626..23686
                     /gene="AKT3-3"
     CDS             join(22626..22909,22969..23190,23247..23492,23548..23686)
                     /NRPS_PKS="Domain: ECH (22-263). E-value: 6.5e-43. Score:
                     138.6. Matches aSDomain: nrpspksdomains_AKT3-3_ECH.1"
                     /codon_start=1
                     /gene="AKT3-3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 201.8; E-value:
                     1.7e-61)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in AK-toxin production"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="BAO10616.1"
                     /transl_table=11
                     /translation="MLNRFSYSSNAWHNLRVDGPDADGIAVIVLARSQSRNALTLPMLT
                     DMVQLLSAMDADDSVKCIVFTGEGPFFCSGVDLTEGFGEIGKTRDTHRDAGGKLALAIH
                     NCRKPTIAAINGTAVGVGITMTLPMSIRIAAKTAKISFPFVRRGIVADAASSFYLPRLV
                     GYGRALHLFTTGALYPAESGLLHGLFSETVNPASSTLPRALEVARDIAVNASQVGVYLT
                     RDLVYRSPRSPEQAHLLESAALYTRYQSRDFEEGVKSFLEKRKPRFQDTMREQSSEGVL
                     ERGDCVVGLASKPKL"
     aSDomain        join(22692..22909,22969..23190,23247..23492,23548..23584)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AKT3-3_ECH.1"
                     /evalue="6.50E-43"
                     /label="AKT3-3_ECH.1"
                     /locus_tag="AKT3-3"
                     /protein_end="263"
                     /protein_start="22"
                     /score="138.6"
                     /tool="antismash"
                     /translation="DGIAVIVLARSQSRNALTLPMLTDMVQLLSAMDADDSVKCIVFTG
                     EGPFFCSGVDLTEGFGEIGKTRDTHRDAGGKLALAIHNCRKPTIAAINGTAVGVGITMT
                     LPMSIRIAAKTAKISFPFVRRGIVADAASSFYLPRLVGYGRALHLFTTGALYPAESGLL
                     HGLFSETVNPASSTLPRALEVARDIAVNASQVGVYLTRDLVYRSPRSPEQAHLLESAAL
                     YTRYQSRDFEEGVKSFLEK"
     gene            28114..29010
                     /gene="AKT6-1"
     CDS             28114..29010
                     /NRPS_PKS="Domain: ECH (45-266). E-value: 2.5e-45. Score:
                     146.5. Matches aSDomain: nrpspksdomains_AKT6-1_ECH.1"
                     /codon_start=1
                     /gene="AKT6-1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 160.7; E-value:
                     5.8e-49)"
                     /gene_kind="biosynthetic-additional"
                     /note="involved in AK-toxin production"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="BAO10617.1"
                     /transl_table=11
                     /translation="MTFSTTKSVAMSPDDDAPSFDINSSRRLMSHSEVESRGNGYEVLQ
                     QAGTVRILLSRPERGNALSLSLAKDLTQLFQTFSSQHSVHRIVLTGKGKYFCSGMDLGE
                     ELYEDATERCLALQDLFGAIDACPKTTVAAINGPAFGGGVGLAFVCDIRVAVSTSFFCL
                     SEVKLGLCPATVSRFIIREWGVSLARMAMLTARKIHPQALQEMGVLHAVALDEEALKVV
                     TENLLDDLGFAAPQASAWCKALTRKTRNGNSDHDQFARQISETMVAPGSESEYGVAQFR
                     RGRKNIRWEQAECLHTR"
     aSDomain        28249..28911
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AKT6-1_ECH.1"
                     /evalue="2.50E-45"
                     /label="AKT6-1_ECH.1"
                     /locus_tag="AKT6-1"
                     /protein_end="266"
                     /protein_start="45"
                     /score="146.5"
                     /tool="antismash"
                     /translation="QAGTVRILLSRPERGNALSLSLAKDLTQLFQTFSSQHSVHRIVLT
                     GKGKYFCSGMDLGEELYEDATERCLALQDLFGAIDACPKTTVAAINGPAFGGGVGLAFV
                     CDIRVAVSTSFFCLSEVKLGLCPATVSRFIIREWGVSLARMAMLTARKIHPQALQEMGV
                     LHAVALDEEALKVVTENLLDDLGFAAPQASAWCKALTRKTRNGNSDHDQFARQISETM"
     CDS             complement(join(29693..30348,30416..30781,30839..31102,
                     31165..31224,31282..31432,31489..31560))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 341.1; E-value:
                     1.8e-103)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450 monooxygenase"
                     /protein_id="BAO10618.1"
                     /sec_met_domain="p450 (E-value: 7.4e-66, bitscore: 211.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTIDMQVLYVTCTVLAALILGYIQAMIIYRLWFHPLSKYPGPW
                     LARISNLYSAYYAWSGDLHIDMWRCHQKYGDFVRYAPNRLLVNTNTGLKAIYGFNKHVQ
                     KSTTYNVMVHRAPSSLTMTDPQESAQRRRIVGQGFSSTAINQYESIIMEHVQRLATQLV
                     RRGSDRGSGWSAAQNMSDWGNHFSFDVISDIVFGARHETIGKPDNRYVLGCIDGANIRT
                     SVLFQAAELTFGRVDRYLFPKSIESRNRFTPFVSSLVRTRLQSHDASRNDAFSLLVRAK
                     DPETSEGLSMDAIGGECTTLVMAGSDITSTVIASTLFYLSTHTESYDRVKSELQQAFPT
                     ADDVRLGHRLNSCRYLRACIEESLRLSPPVGGAPWRRVVSDGLLVDGQSIPAGCDVGTS
                     VYALHHNSAYFKAPFVFRPSRWLTDSGAQGRESRDIRLAQSAFAPFSIGPRSCLGKGMA
                     YAELTLVLATLLSKYDMRAAEGPMRGIGGGRVGAPWGRHRENEFQLTGHVTSAKTGPYV
                     EFKKS"
ORIGIN
        1 ccctatgtgc cggaaacaac caacgggagg gcaaggacag cacctttccc gacacggggc
       61 tgtgtcttat tggttgtttc cggcacatag ggctctccgg tacacaggga gagactttac
      121 aactgtgaaa cctcggctat aactctaacc ctgtctaatc ataaaggctg cttatacttt
      181 gtaacattct cgacgtccat gttgttcaag ctttaacatg gctgggcaga ttacgtgcta
      241 cctagactgc ggtatgtatg aggccaggcc tattcgttca ccaacactaa ttcagactca
      301 agcatcgtta tagtgttatt tcgccctgct atatattgag aagcaccgca atttactgaa
      361 tactcatgat gtagcaatag agtgagcttc cttttgtgat cttgatggtt gttcctgcgt
      421 gacgaaagtt acaacagaac aggtttcatt gtttaacggt gataaatagt gtggtaccgg
      481 ttcttttagg gggcattatt cgcggtagcg gtacgaattc gccctcttgt ttaactcggg
      541 actctcttgt ggataacatg aactaggaaa taaaccgcca tcggaagctc ctgcaaaaca
      601 cgcgaaaata gcatatggag cttttaacat agaccgcgcg aagcgctact tcggtgttcc
      661 taacgtcaag atgcctggat cttcccctgt ccattcgctc cttccccaaa gagcccttat
      721 ctatatcaag gaagcgcacg aatcagcgtt tatcgccgtt ttcctagaca tcttccaggc
      781 aatatgggag gacggcatcg atattcacaa tcctgagcaa tttgctaatg ttttagcacc
      841 ccgatttgag aaggacgtgg ttacaactat actgagtcgg gcaatcagcc cctacctaca
      901 aacagtgtct gaaagattgt actagacatg cgctcgatcg cggagccttc gggtgtccct
      961 ggttttgggt gaagaatgcg cgaggcgatg aggagccgtt ctttggtagt gatcggtacg
     1021 taggtcttag cattttgctc tagaagcggc tgtgctaagc acagaaacgt acttggtgca
     1081 agctattgca cggtagaacg cttcgctaac gcaaaatata ggtttcattt tatgtgggag
     1141 tatcttgagt tgctatagat aaattcccaa tcgtatcctc tggccctcta ctatcaacat
     1201 ccatcgctgt gtggcgcaaa tcccagtgta ccgcaactta ccaatcagct tgcgagaatg
     1261 acgggcttct tcacgattct cgcgagctga ttggttggct gcagcacacc gggatttgcc
     1321 ctacttaggg atggacgctg ccatccttgt tttctaattg gcttttctcg gcccaccgcg
     1381 ttgctccccg cgtagggagg gacattagcc aggccgttaa cgctcgctag cgttttgtat
     1441 cccctccaaa cgagaaatct acggcttctg cgttcttatc ggtgttacat ggggttcggc
     1501 tatacttctc tagttaggca gagacaccta tatctgggcg cgagattgta tatggttatt
     1561 tgggagtcgt aaccatgact tgttatgttg gctggtgctg ccaatgaagc tcacaaaaaa
     1621 gcatgaattc gtcggttttt agttgtttcg ttttaacgtt acctggcttg ttaacctcct
     1681 cccccccttg tgtgacgaga acatctggtg tgccggaaac cacgaatgag agagcaagga
     1741 tagtaaaaag ccctccctgt gtgccgggac cggccaatca gctcgcttaa atcacagact
     1801 tcagccccaa atcagcgatc tgattggcct gtctcggctc ggcacacagg gtgtctcgtc
     1861 acagagggat ggacgttagt tataactcag accaagtaca tttcaactaa attccctcct
     1921 tatgtgccgg aaaaccctat gtgccggaca cagccaatga gatagagtac cgtgtcggga
     1981 aagatgctat ccctgccctg tcattggctg tttccggcac acaggatttt ccggtacaca
     2041 gggagagact ttagactgtt caatgatggt acgcatagct ttcactgcct cattgagaca
     2101 gccagagaac tcggcaacgt ctctgtctct cccttgtacc aataccaatg ggtccgtatg
     2161 gtacacttca taatgtatga acaggctgtt aggatgaggc atcaagaagc ccgcttcttg
     2221 catgcgtagc cagccgccag agcctaaaca gtcagttttc accagtttag gtgtcgcatt
     2281 tctgtctgaa tgtttccatg cttctgactt gaataatcgc ggcaacttcc gtccctcact
     2341 ttctatgaat gcctggaatg catacaatgg ctcaacgaac ccgcgaccgt ctgcaacttg
     2401 ccggacgttc tgtgtgtgct tggtggttga ggcccgcagc tgtaccaaca tgtctcgtcc
     2461 acgtattgtg cttttgccac cagaattgtg ttggataaca gactctatcc attccataac
     2521 atctggagtc acaatctgga gccagtccgt acgtccccat gcgtatttgg ctagtgttac
     2581 agtctcccac actggttcga aacggccata aaacaaccga attgcgaaaa cgattgccat
     2641 aagtactgtg cccttggagc gcaatcggcg tgtgccaaga aatgtgcgat tgagatctgc
     2701 ataatgctgg gagaaagccg caacacatgg ataatgcgcc aagttccgta gccttttctc
     2761 ctcgatagca gtggttatgg gtggcgggat ctcaaaacca agctctcgga aaaccgaaag
     2821 acgctttgcc ggacatttct catgatcctc ctgtaggata tctatatggc ctcttgtcta
     2881 tgctaagatt tgctcggtaa tagcttcgtg caattgtttt acgctgaggc catccagggt
     2941 ggagttgagc ccgatgagtg acgaaactcc atttgcggca acggaaaatt gcagcgtctt
     3001 atccaaccaa cggttagata gatgacgatc gttcaaaagc tgcgaggttg ctctctcacc
     3061 agggtttgtc ggagcgccct cgtcaagaca aataacaaaa gcagctgact ggattgcttc
     3121 gagcttagat gcgttacctg taatgctttc caatgagccc ttcaattgtg cccaatcatc
     3181 tctcctgtgc gaagtgagga tggaaagtgc ggggatggcg tcctctgaat gctggatgac
     3241 gtcttcaaac aacgccacaa gagctgcaag tccatcgtca tcgtggacgg tagctacaaa
     3301 aatatggcct cgtctcataa tcgcaacatt tccgctggct ctatattttt ttctcataac
     3361 atccagctca tgtctcggct cctgagtagc atgaaaaagc cactgtaagg tactcataca
     3421 caacggtgat ccattcaagg agttctgttc caagacaccc atatcaagct gatgtttgaa
     3481 acttagggtg gaatgaacga tgattgcagc ccgctctgct tgcgtatgat taggggcttg
     3541 gccagttata tgtccgaggt agaagacggc atggtcttga agtggttcac gcctctctag
     3601 atgaagggct ttttcataag attccagtcg caaattgcta cccgtgaact tggaaacaat
     3661 agcatctcta tcagcttttt cgacacctct ccattcagct gaggctctta gggtttcctc
     3721 aagctccgct tgtgtacaga agcctttccg cgattcgata agcatgtcaa gggcggtatg
     3781 gaaatccgga gcaggaaggc gttgaagctg tgcacagggt gtctccagca tctcgggggg
     3841 ctgcgagctt ggtgctagcg acagtgaagc ggttgcatct atagaaagag cctcatcatt
     3901 gctgttcggt actttgctgg atatgctgct gggcacaaga gccgagcggg atgcaacttt
     3961 ggcgcctagt gacagaaggt tctggctctc catcgtctca gggatggata tgcttgcttg
     4021 gagctccttg ttgatccaat ttcgaagttc tatgatgatc aatgagtcaa cgtagaagtc
     4081 agcgatagat gaacctagat caacctcgga ggcgtcggct gcgacaaggt ttgccacctt
     4141 ttctcctatc cagagggcca tcaactgcga gatcttttca aaatcccgcg tctcttggat
     4201 ggtggccttg aaagtcttct tggcaccaga tcgcttcccg ctcgtcttac gatcacctca
     4261 ttcacgcacg tgggtaaaca tgggcgagtg cactgtgcca ttagctgcgg tggtcagaga
     4321 caaagactcg ggcgtgaagc cgatgatggc ttgcctgcat ctatgccctt ttctggcttc
     4381 agaagtgacg gaatatcgga agaagcctag aagttcatcg ggtgtaatag atattaggcc
     4441 ttgtcgacgt aatgcttgaa cccgagtttg attgtccgct gttgcatctg ctccttcgat
     4501 tgtaccgata ttgagcgaca tatagtggca gccgtccctg ttgctaaatt gagcgagtgc
     4561 atcttgcaca gagtttccgg cgttggaatt cgactgccca ctggtgccga tgacagtgac
     4621 ggccgatgaa agggagataa aaaaggctaa gccttccgga gcaaatgcgt ttctcaaatt
     4681 catagtcccg tgcgcttttg cacccagaac gcggttgaat gagtcagacg ttatgaaatt
     4741 catagtcgag tcttccagtg caacggcagc ctgaattatt ccccttacag gtggcaggcc
     4801 ctgtgtcttg atgattgtca atgcattctg gacttcattc aagtcagcga tgttgcattg
     4861 aatatcctga agaacacagt catttccaac gttctcctgg agttccgtct gcaaagatgt
     4921 tagttgcgtg tgagagctcg acacgccgcg cgagagcgtg acaaaatgcc gggctccggc
     4981 tgcgcacatt agccgaataa agcgctttcc caagtcgcct cgacctccgg aaacaacata
     5041 agtagcgtca gaatccagac tcagcgaacg cttctctgag gaccacactc tcacgaggca
     5101 gtcgtcaacg tgaagcaacg tgctttcgtt acgatgatgt tgatattcct gcttgaacag
     5161 gcggtctagt tctccgacag gccgagagac gacattaact gctttaatat ccatctttga
     5221 actgccaggg gcatcgacca cggtggaaaa ggcgacagca acagcttctg gctgtgcctt
     5281 cacgaccgca tccatgcgaa atcgagatat tgtagtgtcg gaaagatact gtaattgttc
     5341 gatttgcaac gaaggcttcg gaccgttctc gatgtgaatg cagtggccag acggcttcag
     5401 agtaccagct acttcttttg acacgcgatt tttcgagaag cccagaataa catcgacttt
     5461 tctttgtcca agcacttttt gcagttggtg ttttgatgag tagccttgat cgggaacaac
     5521 gtgatcggca aacctgctga ctacgtcgtc tagcgctgca gactctacat cgcctgacac
     5581 ggtctgaatg ataaccgatc ctagtgcttt cgcgattgcg actgctgatt gcgctatcgt
     5641 tcctatcgcg ccatgaatta agacgatagg gctgttggtc gaggccatgt tgaccaaagc
     5701 atgggaaact gccatcaatg ggatcaagag cgcagcagcg atcctggagg aaacaccctg
     5761 cggtacaact cgggcctgag actggtggac cctcagcctg ttgggatatg atgacgcggc
     5821 gaaagcgaca atattgtctt tgacttttat tccatcgacc ttgctcccaa ttgcaatcac
     5881 tctacccgcg aaaccattaa tggaacgtcg gatgagtagc tctgggactc caattgcttc
     5941 aacgtcgatt tcgatttcgt tctcgccaag agacttacgg aaggtatcgt tttccgtaaa
     6001 cactggcatc ttcataaact cactcctctc gatgtcgaga atccaggcct tttggctatc
     6061 gtggaatggc ttcatttccg gcagtcctgt cacattccca ggcatccaac cttgaatgtc
     6121 aggacttgga agcactctgg gaatgttcac ttgtccattc ttatagacat attcgcgttc
     6181 catcgtcagc aaatccgctt tgctagggga aatgactaga cccattatga agctcatgaa
     6241 acggttgcct tcttcttttc cctcttcttg gcagatactt tgctgtacgt ctaccgttat
     6301 catctctaat cggtcatttt cggcatgtgc ggtgcgagat ataccagtga tgaggtgctt
     6361 ggatgggttt tctgaaaact gagggtcgtg cacaacgctg atccaaagca catgcgaagg
     6421 ggctttcaac atctctgtaa cgctttgaag ctttattggg gtggcatgag agaggactgg
     6481 atgttcgtca ttgtcaatga caagccgaat gctggaatca tgtggattga cggtcatctc
     6541 atcccatgac gttagcgaaa cctcgaattc ctctgctctc agtttactca atacttggtc
     6601 agcaaatttc ctcagccaaa ttggtacgct agagtccagg acgatctgaa cctgcttctt
     6661 tttggtgacc tcttgtatag gcttggcaac tatcaggctc gaaattggtg tttcgttgtc
     6721 gtcgtaaact gcgagttgca tgttcagcga tgctttacgc atccttgtgg accagccttc
     6781 tggtgagagc agaggccccg cggctctgct atcgtttaca cctttccacc aaccaggcag
     6841 agtaccaaag gtcacgttgt ggtagtgccg cggcttggtg acctcaagca gcaacaagac
     6901 gccctctggc ttgagcaatt gacgaacctt ggacagcgta gaatcaacgc tcgaagttgc
     6961 atgtagcaca ttgcaggcaa gaatgatgtc ataaaaaccc tctgtaaaac cctggtcctt
     7021 tgggttcttt ttaatgtcca gagttcgaaa atttaccaca tcagaccaat cctggagtct
     7081 ttcttttgcg ctttcaaaaa atccagcaga tgtatccgtg aagtcgaaaa ctacggggcg
     7141 gttgccgttg tgatccaagg attgaagaaa aggcaaagtt gcacctcctg taccagctcc
     7201 tatctctagg acagtgaagc cggattgctt gaagcttttg gacttgagat acccggccat
     7261 caaatcatag caacactttg atgaatcatc tgcgtatact cgatagagca acccgtcttc
     7321 aagcattagt tgcagcgggt tcactttgcc agtgatgatt tctggtaatg cagggcctag
     7381 acgtgccaga aattcgcctt caattccttg agaagatgac atttccagaa ttttcgcctc
     7441 tgttggatct tcacaagttt gggttttcgc tacagtactg ttcatccatt tcaccagtaa
     7501 cttatgatga tctccggagg tatccaacgc acgcttccca aggtgctgaa gacagcgtcg
     7561 gatataaata tccgtagcgc gatcgattgc atcccatttc tgcttcaccg caggagggag
     7621 ccttggaggc ctcaagaatt ctgctgatat aaattcgaca tccgcgtccc atttcatctc
     7681 atagcagata tcccttgcag ttccaaaggt tacaggttgc ccagtaggag ccaatcgtcg
     7741 cagttccaat ccagatacag acatgaccgg cctgtcagtc gcatcgccac cgtcagaaaa
     7801 taccaagata tcagcgtcac cacctcggag atcagcggaa gtcaaggtag ttatagctgc
     7861 caaggaaaag ccggactcat tgtgaatcag cgtcgacagc gccaattcgt caatacgcac
     7921 tggcatgatt gatgcttgtc ctacttgacg attcaccagg ggcaggctgg aatgcaagag
     7981 gatgtccaga gtggtaggat ggatgaagtg aggacgcatg tattgtgctg gcatcatacg
     8041 agtgacatcc ggaatcgaga taaaggaggc tgaacggtct gcttgtatga tagctttgtt
     8101 gatgccacga aacataggac cataggtgtt gccaacggca ccaagctcat cgtacaattc
     8161 tcgagacgag atttttttca attgcttctg actccacgtc caacccctct gagatttgat
     8221 caaaggtgac tggaataccc aatgcctttc ggggtcgatt agcagctgcg tacatcactt
     8281 ctactgatcc cttgcagtgt tcagcccaaa ttccagctgc cgacactgcc gtcatgacca
     8341 aatgaaaggc atttccgttg gttggactaa cagggcagaa gtttagctga agttccactc
     8401 gagagggtga ctcagggatg ataagtgctt tggtgaagga tatgtttctc atgacaagcg
     8461 tttctatgtc ttgcggtgga tctgtatctc tagccaactg accggcggcc tccatcacca
     8521 tacataagta gccagagcct ggaaatatga tggtgtcatc aacgatgtga tctttgagcc
     8581 aaggaagccc ttctactccg atcaagtgcc tccatgatgg tcgtaatgga gtatgacccg
     8641 tcaccttcaa tcctaaaagg tcgtggtaag gatgcttgcg caagcgatgc tctctgctga
     8701 ggcgtgactc attccaaaag ctcttggagt ggtcccaagc ataactgggc aaatcgtgga
     8761 gcacattggc ttcctgacaa gtaggatcca gagccctgag agcagcaaga tcgacatgat
     8821 gtccatgctt gatcagttcg caaagcacac caagaattgt tcccatgcct ccagatccgc
     8881 gaacaagcgc cgacatatag ctgtaagtgg attgcttgtc taggccagaa atagattgtc
     8941 tagtaggacc aggaagtgcg ttgtgcggtc cgatttcggc gaagatctga tgagattgct
     9001 ctccttgggg ctgtgcgaac tgtgtccggc acaatgcctg cagagcgtcg caataccgga
     9061 ccgtagaagt aaggttggtt gtccagtacg tgaaatcaaa cccttcccac acctcacgcc
     9121 ctaccacaga cgagaaaaac ctgactttgg tcgatggctg ctcaacacaa acatcaccca
     9181 agcttttctc gtactcttca gccgcagctt ccatgtgatg agagtgatag gcagcatcaa
     9241 cctgaagtcg gcgattgaag acggaatcct tgctgagcat ctcctccagc tcggataccg
     9301 cagtggtgtc acctgacaga gtggaactgt ttaggctatt ctgacaggca actgttgcct
     9361 tgccctttac aagctttgcc acgtattccc tggccgtcgc ttcgccgaga tccgttgcga
     9421 gcatagcccc gttctccatt cccttcgcct tcgcaatctc tgctgagaaa cctcggtaat
     9481 atgcaatctt aattgctgta tcgtgagaaa gatatccagc agtatagact gcagcggttt
     9541 ctccactgga gtggccaaca accgcgcctg gagagattcc gaagcttcgg aaggtttcaa
     9601 ctagagcgat ctgaatggca gtggtgactg gctgcgacag ttgtggctcc ttgagtcgtg
     9661 agctctcttt gtcacgaaca agctcgtcga aaaggtccca agaagctccc agctgacgca
     9721 aaacgtttct cggttgattg agcgagtctt tgaaggctct aaccaccaag agctctcggc
     9781 ccatgccggg ccattgagca ccctgaccgg taaagacaaa attgatgtta gctcttgtgg
     9841 cagtacgtac tgcgctgctc gactttagtt cttgggtgag aacgtctaat agctcctgag
     9901 gagtagtcgc aacgccaccg aaacgccatg acatcataaa tcgtctctga ttgagtgtgt
     9961 atgataaatc ccttagtgac agtgtatcac gttggctcga tacccatttt ttgatattgt
    10021 ttgttccgtt tctatggtct ggatctgggt gcaggaaagc ttcctcgttc cacctatctg
    10081 caggaacttt gctccaagcg ctttggccat ctgcgagaac gtcccaaagc ttcgcagggc
    10141 tcgtcgcccc cccccccccc cctcgggaag ccgacaaccg atgccgacaa tggcaagtgg
    10201 gatgagtggt gactctgatg acattgtagg gttcttcaaa ttgaattagg atgtgatatg
    10261 tgagtctgga aggaggcttg aactagaaac tcggtgtctt caatgaggtg cgtcgaaacg
    10321 agagggtgct tttttggaaa ataggctgct ccatatacaa aggcctcgct tatcaggtca
    10381 taatgctgga tttacctaaa tccctactaa ttaacggcag gaaaagtatg taaaataact
    10441 ggccctcaga cattctcata cagatgttac aagtaacaag aaggattctc tccttgagga
    10501 aggactaagg gttgagggcc aaccagggtc cacgacagaa ggtaacgatc agcgcggggc
    10561 gcgctgggtc acgtgactga cgtctcgcca agagggcaga tgccaccgaa tctcgagatg
    10621 acagaaacat cagagacatc tacggatgcc ataggcttgg caagaagaca cagatgtcaa
    10681 gaacagattg caatgagtat ataggatgga cggatttcat tatcactctc gttgtggtca
    10741 actcaaatag ttcatctctt acacagattg tcaactagtt attctatcgt ttatagaatt
    10801 ggtattgtct ttacctattg gttaatagcg acaactcttt tccacctgag ccttccatac
    10861 tatacctcac tgactaccgc tttagtctac cgagccttag tacggaccga gcctagagaa
    10921 gtatagccga cccccgtgta acactcggcc aggttgaaag atctccctca tttgtcgcgt
    10981 acctttcgag ctagctttgc aaagtcaaat ctttcatcgt ttcgtatagt atgagcaaaa
    11041 tgagagggta gtacaatcat ttcactattg ttcgtaagaa tcctataagg cttgttccca
    11101 tacctctctt tgccttctga gaggatcctc ctgccatgct tcaggaattc gaccttctct
    11161 agaattttag gctgaaacca ctttggagcg ttcacaagcg gaatgctttc tttcttgcat
    11221 agtgggctga aggcgatgag aagtaaaaag caaacgatgg agcttgcaat tcatagtggt
    11281 gtttgatcgt ttagcgctag agtaggatgg gtactcaact gcatatagga taacgatgta
    11341 gggaaaatca tcgtcaggct aagcagactt tgcgtgtgaa atcaagtgag cgatgttctg
    11401 accagaagta gaaataagcc gtgtgtttgg gccattaata aacttctcat cgtgatactc
    11461 ctactgccgt caccgtgaaa aaaaaaacct tgaatcaggt accggctgga tctgccagcc
    11521 gtcacttttc tctctctctt cctccccctc tctctttccc tttttgccga aacgtgcaca
    11581 gttgcggtaa tttcgtcatt aatgtgccga taagcacccg gtacaatccc cgtttcgcca
    11641 aaacgggcta gctgctagaa attaatcggt gagttaagct agtaatatgc atctgtgctt
    11701 ggtcatactc agtggtttgc cgaatcgacc cgggtaaagt ttagcggcaa atgggaagag
    11761 caatgatgaa gtcttgcacg agacttgcga aatcgacggt tggcaagcac taactgagtc
    11821 tgttcagcag cgcaaggctg gtgtagccat tggggatggc agcttcaccc ctgcacgcgc
    11881 agctgcacaa cgggttcgaa tagtctcacc ctccgcatgt ggcttggtgc tcgatgtttg
    11941 ctgcaggatg gtagatgtga ttggtcagtc gccgatgcaa ggatggctgg tttcgtggaa
    12001 tgctgcaagc agaggtgaag ctgcaatcgc tcacgactgt actgtatgag cacataaagc
    12061 tcattaacgt tagtcttctt cctttcgcga cgaacaacga tgtgggccga gaacagccaa
    12121 tgagccactg cgtcaggtcg gaatatctgc tatccttgcg ctcttattgg ttgttttcgg
    12181 tctactgtgt gatttggtgc gcagggaagg aggttagaga gctctttact gagaccggag
    12241 ccgtcgcatg ctgaagccgg tctgctagcg cattcatact tcccgacgct gtgcttgcct
    12301 cgtgcttgaa cgacaccgat ttggcctgtg gccgtatcgt ctagacgaaa tactgtgcat
    12361 aaaagaattc tgcttgtgtt tgttgttcac atttaagcac taaagtctct ccctgtgtac
    12421 cggaaaaccc tgtgtgccgg aaacagccaa tgacagggca gggatagcat ctttcccgac
    12481 acggtactct atctcattgg ctgtgtccgg cacatagggt tttctggcac ataaggaggg
    12541 aatttaccgg cagacttagg ctggggcata aatcgaccta gactggacca aggtttcgat
    12601 accgacttcc taagtaccac gatgtctgtt caacagcggc ttttgactgt tctatcgcac
    12661 aatggcgaca aatgtccctt gtttctattc ccacctggct caggctcagt cctgccatgg
    12721 ttatcattgg ccgcatacgt agacgatcgc cctctatatg catttcgcct gcaggggttg
    12781 gaagaaggag agctcccatt ccaaagtatg gacgaaatac gagagtatgg tctcccactc
    12841 gccgctttac atcaaactga ttagttttgt tcaggacata tgagaaagct attcgatccg
    12901 tgcaacctcg gggcccttat gcattcttag ggatgtcatt tggcgcggta attgcttttg
    12961 aattagccaa acgattcgag caattaggtg aagaagttgc ttttgtaggt tctctggatg
    13021 gtgcaccacg taactctgct gtgcaagtgg caattcccag ctctgagcta ttagcagtcg
    13081 atttattgaa gctgcgcggt gttctatccc aggaggaagc agaagagctg agagagaact
    13141 atcaaaggaa aggaaccgga ggtattattg ggacaataat acactcgcac aggatcgcat
    13201 tggatgccgc cggcttcaca acagacagct tcatggcgtt tgttagaacg ctggatagcg
    13261 gagcaaaaat ctatcttgag tatgaaacca cagggaaggt taggaagttg gatgtatttc
    13321 aagcaaatcc ggtcgccgca tgggacgtca ctgaagagca gtggtcaacc cttttgcagc
    13381 actggactag ttttgttgag gacgttaaat ttcacagggt atctggtgat cacatgacgc
    13441 taattaaccc tcaacatgta ataatgtttc aggcagtttt agctaaggcg ttggctaacc
    13501 gtggtatcta gtgtggaagg gtttggtgga gagaaacata ggaggaagtg ttcctcgaaa
    13561 caatgggaag tgttcctcga aacaatggga agtgttcctc gaaacaatgg gaagtgtccc
    13621 tcgaaacaat gggaagtgtt cctcgaaaca atgggaagtg ttcctcgaaa caatgggaag
    13681 tgttcctcga aacaatggga agctgctcta tgcgcaggaa cggaaccaac gtctatctac
    13741 tggagaatgg gacgaagtga taatctctgt cggctatctg caaaaaatgt gatgatctct
    13801 cgcgtgatgt cgctttttgc ttcgttttcg ttttcttctt cttttttttc cttttttttt
    13861 ttttttttta ccgcgctgct gcctaacatc catcgcccgt gagcgagaga tgttccccag
    13921 agagcttaac caactctaca ggtattgtca ctagcgattc cagcttcacc cctaagcgca
    13981 aatgcgcaat gttttttttg gatagcccca cctttcgtgt ctggcttagc gctagatatt
    14041 ggctgcaaaa caggcgatgt gattggtcaa ccgttatttt aaagatgact tgtttttaga
    14101 atgctgcctg caggagtgaa gctgcaatcg ctgacgactg taacctctct ccctgtgcgg
    14161 ggaacaaccc ggtgggccga acccagccaa tgagagtgca cgaattaccg atatcccgac
    14221 ctgacgcaat atctcattga ctgggttcgg tccaccgggc tgttcgctgc gtagggaggg
    14281 aggtcagttg gatggtcgga aactgccaat gagatacacc accataccgg gagaggtgct
    14341 atcaacgccc tttcctaggt tgtttccggc acacagggag ggactttagc agataaagtc
    14401 cctccccgtg taacggaaac cctgtgcgcc ggaaccagcc aatgagatat agtattgtgt
    14461 cgggaaagat gctatccctg tcctctcatt ggctgtttcc ggtacacagg gttttccgtc
    14521 acacggggag ggactttagg aattacgata ctatcctggc ttgcatataa gaagccgcac
    14581 tgtcggatac agcaagctat ggttacaatc cccaacaacc gtttacaata ttgttctcag
    14641 atataggtgt ttccatctac agtgaagcac gctacttcta tcggactcca ctatctctaa
    14701 acgacagcat gcttcaaact aagaacatgc tccgtgatag cttttacgtc ctcctcctta
    14761 gctggtatga catgccctac gtcaaattcg agatgcgcac gtccagcacc tgtgaaacac
    14821 gaaactagcc gcctctggat ctccaggctc ttatctctca gcccatggat gtgcaaggcg
    14881 gctatgtcga tgatatggtc tttgtaagct ggactggttg cgcatgggaa ctctagtggt
    14941 ggataagcgc tatggatgaa aaccccgaat ttgaattggg attgcatcat cccgggacct
    15001 tcttgcgtag atccatcttc ttgtgcgagc tggaaacttt gatgcttcaa gaggcctgaa
    15061 gctactctcc ccccctgaga gaaccccatc actcctaccc agagttcaga agagatcgaa
    15121 ggtgtcaagt ctgccagaac tgaacgcagg cctgcggact tgtcggcacc agagtggtcg
    15181 tatacatctg gatcatacgc ttcttcgtgc tcctcggtcc atcggtagaa cggaccacac
    15241 ccttcgaacg tagggaggat ctcaggacca ggaccgcact tgtacggccc atcaacgtat
    15301 accagctcga agcggtctct cagatggtgg cggatatgat atgtttgggc tttgaatatc
    15361 tctgcagagc ttccgaggcc gtgaaggcat aagatcagag gcttgcgttc ctgagtcatg
    15421 atagacaagt tccgatgtgc cgcgaatccg aacagggctt cttagtacgt aggcaagcct
    15481 ggatcttgtg accgtactgc tgtaagcatg gatgatgtaa attttgttct cagtcaggtt
    15541 tctatagact tatattagtc gagggctaga cgttacatgt tactgtgatt ggagaaatca
    15601 atgatgctta gtttcccgct tactttggtc aaattgatgg tgcaaaatgt tgctttccac
    15661 ggcctctaat cattggtttt ggagaaagtg cgcatttggt gtacctcggt ggattaacta
    15721 gagaaaattg actgtatgta gtagctaaga ctgcatgtaa gaaacagaca aagacgtgga
    15781 caaaacactt gccggtgaga agcagcagat atgcagcttt gccggtgagc caaagcgcta
    15841 ttacagtatt atacggtata tacgaggcgc atacgctgcc aaaactattt cggatggtcg
    15901 tcggaatatt agcaaagtat ccgaattgtt cttcgcctgt acaatccccg attatcgcca
    15961 gactccggat atgtacccag cgttgactcg cctgcttgca tggttcacat gcttcctcag
    16021 tactgcaata cccaaaaccc ctgtgtagca cgacctgccg gataagttca cggatcccag
    16081 gtgcgatctg cattggtacg ctcgaccaca ctgatgccat ctggcccaat gtcccctctt
    16141 agcgtacagg agcatgtggt tctgtgtcct cgcttgccga gagcggcaga ggttagcgtg
    16201 gactgtgtgc gcttagcggt caaacaatat tcccctcagg ttgccttgcc aggaagcaga
    16261 ttcaacgtaa ccatagtagc ggcacatgct aatggtttct ccaaagtgtg ctatccgaga
    16321 tcttatcgct cttcagcact aatagcatta ggaactatac gaacctttgt gggactattt
    16381 acacgcagct ctagcgtcga aaaacgtagg tatcagatca atctggattg cggacatggc
    16441 acatcaggga gctagtctag cgcttaacaa atcatctcag ttcacggaaa gtaagtccaa
    16501 aactcttttg gtactatttg tgtgatgatt ggttgatgaa tatgattgac agcctcatgg
    16561 caagatcacg cggacgatct cctgcacgtc ataaaatatt tcagctctca gatgcagcag
    16621 cccatcattg gtgttggaca cagcatggga ggctgtcaga tgtacgtaaa aaatcgcaac
    16681 cctgacctgc acagacaagt cctactcaca ccgatttcaa gagcaacgtt atccgttact
    16741 tcccgcagaa tgtttagtac tatgatactg ttggaccctg ccattggtcc acctgacatg
    16801 ggccttgcaa cccttgactt gggtcaattg acattacgac gtaggacgca gtggccaacg
    16861 agagaagatg ctgaaaaggc gctgagaact tctttcagta cgtgggattc gcaagtcctg
    16921 aatctcctga tcaaacactc tatccatagt gacaaacagt cgattgagat ggaggatggc
    16981 ccggtcagtc tagtcacagg acgatatcag gagctggtca actatatcaa gccctccttc
    17041 attcgctctg gaaaggtgaa tggccaagag ttgatccatc agacaggccc tgtcgatatg
    17101 taccacatgc ttggcctcgt aacttgtagc gctctatact tgtgtggcgg agagagtacc
    17161 ttgagcgttc ctagggtcag ggatctttgg cttaaccgaa cggcaaagct ctcgtactca
    17221 aaggagccgg gagagacgag gaaagtggat gaaaggattg tgccagacac aggacatttc
    17281 ttgcccatgg aggagcccaa gaaatgtgca gatattatag cagattggat cgaaaaggac
    17341 aagtgtatag catggaattg ttgtgttggt aagcgaggaa agacatggtg tgagttaagc
    17401 aacgccagca aggagatgag cgcggaggct tggatgaaat atctgcagtc gaaactctaa
    17461 agtcccttcc tgtgacggaa aaccatgtgt gttgaaaaca gtcaataaga tacagcaccc
    17521 ctgtcgggaa agacgctatc cttgccctct cgttggctgt ttccggcaca cagggttttc
    17581 cgtcacacag ggagggatct tacgttgctc ggcgtacgag cctcccagac agtctctgct
    17641 acatcggttg gagcaggcac acggagctgc acgtcaaacc tggacagaac agcgtctggt
    17701 tggagggaaa caagacctgc gcctcgaacg gctgatgaga ttttggctaa tgtgaacgat
    17761 cgattgaggt cgcatgttgt gtcaaacggg cgccctttag gcgtatggtc tgtttgcccc
    17821 tcgttctgta gcaacgaact agctcccccc tttctgttgc tcacccacac atcccaagac
    17881 agccacattt aacgaggtgc ctaggtatga cacattggtt ccctttcaac cgctgcccat
    17941 tgctcattat ctaacacaat gcaggtctca ccaaagacgt attcggtttg caccccatgc
    18001 aagttctaca gaatagcttg agatgcgcgc tgcagcgacc acggccgtca tggtcgtcat
    18061 tgttccctta tgcctgctac aagggcccaa atgcgagtca gaactctttc catttctctc
    18121 atttccacgg aatccccatc tgaacgtgcg acggagttgc ctacactcct gaactgatag
    18181 aaccacttct tcaactccgt aacctccttt gcgagctgca tgaccgaaga ctttacgatg
    18241 tctcttgcga ccaaagcgct ctcctcttca ttgagcgtct gtcttccaat actgatggtg
    18301 ctttctaaga aaacaagacc cggttgctgt atgcactgtt ccgaactgtg ccgcgaaggt
    18361 tgcttcttgt tgaagtatgt agccttcgcc gcgtcgaata gactgaggag cttgccgata
    18421 gtcttaagca agtcgagaaa cgtcgttttg cctgacaaag ctccttcacg aaccacatcc
    18481 tcgccaagga cataaatgac acagtggtgg tgccgcagca tttcctcaaa gagtaaacga
    18541 gccctgtaca ggaacatccg gtaatcctcc taccaatccg attccagcgt actctgcgtt
    18601 cggggccaga agctggctgg cagtcaggcc tgaatcctag gactccatga gcgcattcac
    18661 tagcaatcgt tcgagataga tgcctaccta ccatgatgaa attgttgagg tgtgcagctt
    18721 tgttgtgtgc agctttgttg tgtgttggca tggatactgc gagtattgca ccgttatcga
    18781 caagctcaag taagagaagg ctggccaacg ggacgctccg gaagcaccgg gagacaagag
    18841 tgataccgca cggaccgagg cagagacagc tgcagggttg tccctgctta tgcgcttacc
    18901 tctctctcgg aacgactggg gcctcgatcg ccgacataac cttgctaaag tcgacgcaac
    18961 cctagccctt gtcaccgcct ctcccagcat cgatagaggg ggagtggcgg cagcgatcca
    19021 aaagctacca tttggctact gtagttcggt ggtgcggtct gtatatccct ctagcctccc
    19081 gattgcgtgg cactttactt ggcccctcaa ggggaagcta tctcagctaa gtaccctgcc
    19141 tgagtcgcgc cgaatgatct tcgctatcgg aaagtgcacc ttagaatctt gtctggatct
    19201 ctaacttgat gtattccgtg tgaaacaggg cggtgctttc agatccgagg gcgatggata
    19261 atcgcgctta cttacagaag tcacgggtac cagtcacggg taccagtcac atctcatcat
    19321 ccgcatcttc tttctcaagg tcgacatatc agcccagacc cacgatgttg cagtgcgccc
    19381 ccaaaaagaa cgagcgactt cgaggttcgt gcgacttttg cacccagtcc aagcttaggt
    19441 gcaacaagaa taaaccgtcg tgccgacgtt gcaccatcca acaacagcct tgcgtctaca
    19501 gcgtcgcgcg tcgcacaggc cgaccgccaa aacatccccg cacggccaat gattgccagg
    19561 aagccaatgg ccagcatggg gaacaagatc cagtgacttc aacacccgga ggctcatgcc
    19621 aacagcagtc gaaccatttg ttggatgtag agggcgacgg cgccaacttc accctcgcgg
    19681 atgccagcac aacggcccag ggtcgagaaa ccccagcctc ttctgcccta gacaatgctc
    19741 ttctcgtggg agaaaccttt ggattcagtt ccctgctcga cgatccgctg atccaaagtg
    19801 atgacttcct cagcttctct ctttgtatgc ccccaggaga agaagaggga catatggcca
    19861 gtcctcgcgc tttgaatgga agcaccggtc cttgcagccc aactgtgcta tcctccatcg
    19921 acgtaccgca cctgcctgcg cgtttcggat tccttgaaag ctccgttgag tccgggctac
    19981 acggtcgtac tgggccacac ttggtcgaac agccggataa gatagtccct tcaagtttct
    20041 ctgagatgga aaagatatat gacgaagggt tgacattttc gggactagac agtgcaatca
    20101 atgcggttac caacaacggc aagggcgagc ctagtgcctc tggcacaatg gctgctcatc
    20161 cccatagcaa acgtcagtgt ttctgttcta cgtctatgag caagctccag atgctcatct
    20221 cccacccgac gctgtgtcag aagaacagcc gcgctcgttt tgacatgacc cttttcttgg
    20281 aggaggttgt ctttaacata catcgggatg tcttacagtg cttggtctgt cagtcgaagt
    20341 ctttgcattc tctagcatcg ttgtgtatat gcacagactg ggtcattgag gcattgaggg
    20401 atgtggctca ggatctttcc tctgggcaag ataacctggg ggggttccgt gccggactct
    20461 gtcctccaaa ggacaagttc agcatctgtg ttgggcgatt cgttctagac gaccagctcc
    20521 gggagtcgtg tacacgaagc ctggtcaaat accgtctgcg caagctggtc cctatcatgg
    20581 acactatgat gaagctgaat tatcgggggg cagggggtgc gctttcgcaa gctattcgta
    20641 ccatggtaga ggatgtccgc cataagatag aatctgcttt gggcatgatg gagctgtaga
    20701 cgaggtggca gtgatgcaaa atgaatgact ctacgggctg tattgagtct gtgcagtgga
    20761 tgagctgtag cgccactcac gatggctttt accgcaagct gttaccgcgg tgtagtgatt
    20821 agatgcttgc aattgttatc tgccgcttga gcttcttggg cgccttgatt gtgcggttgc
    20881 gcgctgtcgt tctgggcagc tgcactacca cttgcagcgc ctgtgacgcg gcaggttgtg
    20941 tgattgttgt aataggtccc tttgcctgtt gtgccaatct ttctcgtgat tacagtttct
    21001 cttttttttt cccgttcttt ttgcgcccgc gcggcgacag gttcctgagt gctcgcctcc
    21061 tccgcccgct cctgcgcctg ctttgcagtc ttttgttact gagggggagg aggagggata
    21121 ggaggaggag gaggggtagg aggaggaggg gtggtttact ccgatttcaa acaaactgcg
    21181 gaagtccttc cagctaccca ccattgccgt actcttgaat cgctaggctc tcatcttgtt
    21241 ctggtgctgg gggttcagaa cctccgcagg acgatgtcag cattggttgg cgcaacgccc
    21301 gaatcttcaa atgctttggg aacattcgcg cacgtgaacg agttcgataa ggtccgcgac
    21361 aataaaaaaa aaattaaaca ataattgaaa ggaatcaaaa atgaaataag agtaaagata
    21421 aaggataggg atagaagtaa agatgagaat ggaaacaaga ataaaagtaa agatgaaaag
    21481 aatcgctctc tttggctggt gctgggcctt gggcatggtg agcatgggtt agaagttcag
    21541 ccgagtacat tcccagaagt gaggaaaaca agataacgtc caaaggctgt aagctgtgag
    21601 tcgaatgggg tggagagacc gccaaacgta tcttgttggc gtcgcaagat tctatagaac
    21661 tattggttat gtggctgcca tggccgtcag gaaaaggggc cggtaacttg actgccagca
    21721 tcctaggctt acaatacatt gttactatct ggcgagtcct gacgatcttc cttcgtatca
    21781 acgtcgcact ctcggattta cgggtcgaga ggtctgaaac acagacagtg tggctatcac
    21841 tcgagtcggg cttatggcga ttgcagtctg tcccagtggt acgtttccat gtaagacggt
    21901 ggttgttttg ttttagaaac cgcgtaaccc acccacgcct cccatgcctc ctgtctcgcc
    21961 acagccaacg cgagattccg tatcatcaac ctcgcaggta caagcacaca gcctgttcac
    22021 ctttctatgt accgtacaaa tcctgattcc tcttgtgggc tggggggctg gcgttgttat
    22081 gatggcgctg tgtaggaccg tgttgcgtcg ctgcgccggc ggctcaatgc catttggtca
    22141 gcaccttctc ttcttcttct ctttcttttc tttttctttc gcggcttcta ggtaggaaag
    22201 aatgtttgcc agagcatgcg atcgaactgc ctcaatcgca cccaaaactg ggcttgtggt
    22261 ggacaccggg cgcgtggaaa acgggttgct gttgctgtga cgttggggta actggcccag
    22321 cgatgtggct catccgctgc gcagactcag tagagcgcac aaacgtcaac gccatagaga
    22381 ctgaggcgct gcatgggaga tagcactggc tctacgatga atgccctact ggcagtttgg
    22441 cacgagtact acagcaaatc accatgtcta gctgccaacc gaatagaacg ctctggggtg
    22501 cgctggattt cggagtgttt ccgcactcat cttccagggg taagcttgct tggcacgctt
    22561 tgcataaaac cctcttctgc tctcgaagca tctgtatcct gcgaaactct acctctgttc
    22621 ctgccatgct taaccgattc tcttattcgt caaatgcgtg gcacaacctt cgtgtggacg
    22681 gtcctgatgc agacggtatc gcggtcatag tccttgcgcg ttcccagtcc cgcaatgcgc
    22741 tcacattgcc aatgctcacg gacatggtac aacttctcag cgcaatggac gcagacgatt
    22801 cggtcaagtg tattgttttt actggcgagg ggccgttctt ctgctctggc gtagacctga
    22861 ctgagggctt cggcgaaatt ggcaagacgc gggacacaca ccgcgatgcg tgagtttccc
    22921 cgcaccctgt atatcgccaa ggcgaagcga tgttaaagtc tagcgcaggg gaggaaaatt
    22981 ggctctcgcg atccataact gccgtaaacc aactatcgca gccattaacg gcaccgctgt
    23041 cggcgttggt attacgatga ccttgccgat gagtatccgt atcgctgcaa agactgcgaa
    23101 gatctcgttt ccttttgtta gaagaggaat cgtcgccgat gccgcttcta gcttctatct
    23161 cccgcgactg gtagggtatg gccgcgcatt gtaagggcta ccataacaaa aagagagctc
    23221 gggccaagtg cttacgccca gaccagacac ctctttacca ctggcgcctt gtatccggcc
    23281 gaatcaggcc tgttgcatgg acttttctca gagacggtca accctgcctc atcaaccctg
    23341 ccgcgtgcat tagaagtagc gcgggacatt gctgtcaatg catcccaggt aggtgtttat
    23401 ctaactcgag acctggttta tcgatcacca cgaagcccgg agcaagcgca ccttctggaa
    23461 tctgcagcac tctacacgag ataccagtca cggtaagtcc tggcttatat cctcatcata
    23521 taggatccgc ttgaccttta tccatagtga cttcgaagag ggcgtgaagt cattccttga
    23581 aaagagaaag cctcggttcc aggacaccat gcgtgagcag tcgagcgagg gcgtgcttga
    23641 acggggagac tgcgtagttg gcctggcttc caagccaaag ctctgaccaa accatgaatg
    23701 gccggccact agctcgaact agacagaaga aaggaagttg tacgaaccat tggcaaagtg
    23761 taggtttatt gccttgctgc taggggcttg tttctaaagc aaagtggcaa tacttcgtcg
    23821 attggcctgc tgaccactcg caactgacat tgatgcattc gtgtggactc cgggggtgtc
    23881 gatactgact actgttagct gccataaacg cgcctggtct actttctggc attctgtggt
    23941 agaggcgcgt atgtctacat gcccgaatgc ccgagaagca tggtggctgt cccctagaaa
    24001 aagaatggga tagcgaacaa agatctgaag gactggaaag gtaccatagg tctagtctct
    24061 cctacggtgt cttaggcgtt acctatacga aaagagtctg ttctaacgca gctacacttt
    24121 gcatatcaga atactagaag ctttaacggg tttctgaaca cgttgagcgc ggacagatac
    24181 tgtcgcgaaa gtctttcttg ggctctgctc caccacttat cttcctaata cttgtgtgaa
    24241 gaatggcctt gttctgcctt ggcagatctt cctagggccg ggtcttggag atagagcaag
    24301 tcgtcgagta cgcgggttgg tgggatatac tagctcgatt cgaagatcgc tacgacagta
    24361 cggtggttga ggaacgaatc gtaacattga gatactatcc gaagttgagc aatgtgcgct
    24421 gtagaggccc attgcccact gctatactaa ggcgtgtcgc gctcgtggaa gagcggcgca
    24481 ttgcttgctg atgggcaact gtctgaccgg tgacttgtgg gtgctcctgg acgagcattg
    24541 gctgcctggc ttgacgtaag ccgctgattg acagacagtc acgtgactgg gatgtggctg
    24601 ccatgccatg ttctgtggct gggcagtatg atccttcaac acgcttaccc tcgcatgcac
    24661 ttgcggcttc cgctttgcac acacgaccct gtttgtcatt gtgcactagg catcgactcg
    24721 tccgttgtac acttgctccg aaaagactta ggctctgtag atatctcaat tccattggtt
    24781 tgaatatcga gcagagggtt ggcttatggc aatgctaacg aaagctagca ctattgaggg
    24841 aaggctatga ctaaacgaga atggcttagc atgggacaaa aagtcgcctg cttacagaaa
    24901 ccggaagctg caagtgcatg agagtgtact gttatcgctt ggtttccttt atcgggcggt
    24961 ttcttcgggc ggttgcttcg ggcgactccc atgcgtaata gtcagcactt cagtagctag
    25021 cacagtgctt agcaattacg atttccacat gcaattagca acaatgaagt tcaccacact
    25081 gctaacaagg attaccggta agcgcaagat caaggggtgc acgtaatctg cagcagctct
    25141 ggtgtcagca caaagccctc tgaggatatc gcagtctgtg ctcgcactag ctcccgcagg
    25201 tcatagtggc acccccatct tgatattact gctgaccgtc agccttgcgc actcccggac
    25261 atcgtgaaag gctggaacgt gttagagtcg ttagcgattg cggcttcacc cccaaacaca
    25321 gttgcgcaat ggctttggat agccccacct tccgtatgcg gcttggtatc agctgtcttg
    25381 cagcgaacat gtagcgccaa gccttatgcg gaaggtgagg ctgttaaaaa ccgtcgcgca
    25441 gctgggtata agggcggagc tgcaatcgtt gatcactgca cacgtacgtg ttcgcagtct
    25501 ggcttaaaag cgttgattac tagctaagta cgatattttg cagtccaaga cactgcgtag
    25561 ggacacggaa ggtgggcaga tacgagcaag atccgtgcac ctagtacgag cgtctcggat
    25621 acccccagcc aatcaacaag atcgatgtgt tctagcgcat ccgggttgtc ccacagtcgt
    25681 tcaggggagt cacagtcgtt actgtggcct ccgcgtccag cttctctcag ctctggcaga
    25741 catctgccat gtctcgtcgc agccaagtcg tactcgccac cagactcggc aaggctcttc
    25801 acgtcctaca ttccagacta tgatacagtg taggacgtgg atggctttac tgagtctggt
    25861 ggtgagtagg acatggttgc gacgagacat ggcagatgtc tgccagagtg ctttgccact
    25921 tctacacagc cggtacgaat gatatgtaag tctgctcttc catacatggc caatggccaa
    25981 gtagcgcttg agcagcatct tacaatattg tagcattgaa cgatacaaac gataacgtgt
    26041 accaccacta ctctcttcta ctttattgta cacgtaacgc gttgtcgctc gaacatggag
    26101 gacgacttca gcctacccta cgagtctaca gctccgccta attttggagc taccaagcta
    26161 ctgctactgc tactgctact gctttgaaag ttaacaggta agcactcggc cgacatgcca
    26221 gaggaatccc cttccgcccc gaagctacaa ctaactgcct caagctcgca cccgccgaag
    26281 aaaaaacgac tgtccaatac atgctcgacc tcgatttccg agaactcgcg acccggctgt
    26341 gcgaggtggc tgatacgagt ggaaaactcc tgggtattcg tgatggggga aaggctggca
    26401 ggcacgcact gagctgagtg tttgatggca cgttcagatg agctcgaaat ggccttccat
    26461 cgagtgaagg ccatgcagag gatactacag gaagacgcag aagtgactgg cgcgtggttc
    26521 cggctggtag aagagtccaa ggctaagcac ggtgtccaac aaggacatgc aactctggtg
    26581 aggctggctt ccaggtgggc gttggagtgt ctgtttaaag tagtaacagc atctgagagg
    26641 cgtactaagc cacttggagt tcaacctagc gatcgtgagc gggtaacgtt gatggctggc
    26701 atcaatgcgg tagagtgatc aattccacta ttacttatcc ttaaagcaaa acaccacgat
    26761 cagatctagt gttataacaa cccaagggat agaaggatag gggttggtaa caacggctgg
    26821 acaacgaacg agcttggtct tgcctagtgg cagcatttta tccagcagac agcggctcgc
    26881 acagtgggta gccatcgcct gcctaccatc gatggccacg agagccacca gtcacttgcc
    26941 ttctaggatc tgtgtgagga gaacaggatt attgccctct atgcctccac acttgtcgca
    27001 catcctacag ccgcttgatg ttggttgtct tgccctgctg aagcaggcgt acaagaagga
    27061 actcaggggc ttggcagaca gccacatcca ccacatcgac aaaaaagcct ttctaactta
    27121 gccacctttg ggccagtgtt tgaaaagtcg ttttcaaagg atcaagatcc tatcgagcct
    27181 gagagcaact ggcttagtcc cacataatcc agaggtggtg tcatccatgc tcgacacgtc
    27241 cctggtgact tgttacacta ccggaattcg ctagccaatg tcatgatctg cgtctgtggc
    27301 agggctcggc tagctgaatt tatagtctct tgtcgcacgg ttgagtgcag gtattctaaa
    27361 cagaaatcca aagagagtgt atgtagtatt gttagtagcc tcctagcaca acttgtatta
    27421 aggtcatcgc cgcacggcgt tatttagtaa caaggtttcc ggcagcgcct gtcttgcgac
    27481 atctcttaac accagtgact ttggaaaatg gcctaacatc ctgccttgtg tagcgagaga
    27541 ctcggtataa cctctgtctc tgcgcagcga acaacccggc gggccgaaaa caaccaattg
    27601 aagcataagg ataacagatg tgttgacctt acacattagc ccatcagcca ataccagccc
    27661 gcattgtagt tcgtcgcgca agagggaagg ttacgcctca cagtgaggcc atacaggggg
    27721 actttatgcc atgtttggtt gagctgattg agagcttgaa ccctgcagat accacagatc
    27781 gggggctttg acccagtagc gtgcgacatt gttcaattgg acgtaagagc aatattgcga
    27841 tagttgtatg gtattaaact tgtgttcgaa aggatggcgg tccataggcc ttggcacgaa
    27901 aatcagccac ggcgggtttg gaacgtgatc ggaatgaact tgtcgtaaga gtaaactcat
    27961 cagtaagatc gggtaatttt attgtcattg agtatgaggg tggggctccc agcctaacta
    28021 tgcgatacat cgcctgacta gaatttctac tcctatagaa ccaatttatc aagtaggacc
    28081 tattttccta gctagaaatc ttctcaggag aagatgacat tttccactac caaatcagtg
    28141 gcaatgagcc cagacgacga cgccccatca tttgacatca actcttcaag gcgcttgatg
    28201 tcgcactcag aagtcgagtc aagagggaac ggatacgagg tactgcaaca ggctggaact
    28261 gtacgaatac tgctttccag accagagaga gggaacgccc tctccttgtc cttagctaaa
    28321 gatctcacgc aactcttcca aaccttctcg tctcaacact cggtccatcg tattgtcctc
    28381 accggaaaag gcaaatattt ctgttctggt atggacctcg gagaagagct atacgaagat
    28441 gccacggagc gttgtctagc gctacaagac ctgtttggag ccatcgatgc ttgccccaag
    28501 actaccgtcg cagccatcaa tggcccagca ttcggcggag gcgtggggct ggcctttgtc
    28561 tgtgacatac gcgtggctgt ttcgacgagc ttcttctgtc tgagcgaagt gaaactgggg
    28621 ctttgtcctg ctaccgtgtc caggttcatc atccgcgagt ggggcgttag tctagcccgg
    28681 atggccatgt tgacagccag aaagatacac ccccaagcat tgcaagaaat gggggtactt
    28741 cacgctgtcg cattggacga agaggcattg aaggtggtca cagaaaacct cttggacgac
    28801 cttggatttg cagctcccca agcatcagcc tggtgcaagg ctttgacacg aaaaactcgc
    28861 aatggaaaca gtgaccatga ccagttcgct aggcaaatat ccgaaaccat ggtagcgcca
    28921 ggttccgagt cggaatatgg agttgcacaa tttcgccgtg gacgcaaaaa catccgttgg
    28981 gagcaggcag agtgcctgca cactagatag atagagtccc ttccagtgtg gcggaaaacc
    29041 cagtgtgcca gggacaaccg atggggaaat agggataaca gttttgctga cgacatgttg
    29101 tgtctcattg gctgtttctg gggcacgggg ttttctgcta cacagggaca aaatttagtt
    29161 gatgcaagca aaagatgcag accgtaaagg tttcgatgca tataaccgca aactgagatt
    29221 atgaataaga atccatgtcc tcatttcatg ctatctaacg tgtctagaca aagcttaatg
    29281 taacctctct ccctgtgcgg cgaacaaccc ggtgggccga aaccagccaa tcagggtgca
    29341 cgaattgccg atatcccgac ctgacgcaat atcccattgg ctgggttcgg cccactcggt
    29401 tgttcgctgc gtagggaggg agattaggtt caagggaaaa gtgcacaaga cacgttgctg
    29461 aacataaaac gatcacacgt tgaccccagt ctgccatgcc tgttcatact gctcgacgtc
    29521 gttcttgcac tgtggcctga acagcatcag ttgtttcaac gctggtgagt tctgtattcg
    29581 aaagatctta ttattcttgg tcccaattga ctacccgacg tcatgcttgc attgtggttt
    29641 gaaacacgcc ggaatggtca acgcctgtgt tcttggttct ttctgaaatc gatcaagatt
    29701 ttttgaactc cacgtagggc ccggtttttg cagaagtaac atgtccagtc agttggaact
    29761 cattctcccg gtgcctgccc catggcgccc caaccctgcc tccgccgatg ccgcgcattg
    29821 gtccttcggc agctctcata tcatatttgc ttagtaacgt tgccaggacc agagtaagct
    29881 ccgcataggc catgcctttc cctagacaac tgcgaggtcc gattgaaaag ggtgcaaaag
    29941 cactttgagc aagccggata tccctgcttt ccctgccttg cgctccacta tctgtcagcc
    30001 atctcgaagg ccggaagaca aatggcgcct tgaagtaggc actgttgtgg tggagagcat
    30061 atacagatgt gccaacgtca catcctgctg gaattgattg gccgtcgaca agtaagccat
    30121 ctgagacaac ccgacgccaa ggagcaccgc cgacaggtgg agatagtcgc agactctctt
    30181 ctatgcaagc tcgaagatat ctgcacgagt tgagacgatg gccaagcctg acatcgtctg
    30241 cggtagggaa agcttgttgg agttcagact tgactcggtc gtaagactcg gtgtgagtcg
    30301 acaggtagaa gagcgtggat gcgataactg tggacgttat atcagagcct ggagatacct
    30361 cagtaatcag agatgaccat tgagggtctg tcgttgaaaa tacagggaaa cgcaccagcc
    30421 attaccaagg tggtgcactc tccaccaatg gcatccatac tcagaccctc gctagtctcg
    30481 gggtctttgg cacggacaag tagagaaaac gcatcatttc ggctggcgtc atggctctgt
    30541 agacgggttc tcacaaggga gctaacgaaa ggagtgaatc tgttcctgga ctcgattgac
    30601 ttggggaaca gataccggtc gactcgtcca aaagttagct ctgcggcctg aaacaagaca
    30661 ctggtacgga tgttagctcc atcgatacat cccaagacgt agcgattatc gggctttcct
    30721 atcgtttcgt gcctcgcccc gaagacgatg tccgagatga catcgaaact gaaatgattt
    30781 cctagggcac agatgtttat acgcgaggat gtggtaaaac actcaggtgg atacttaccc
    30841 caatcagaca tattctgtgc tgcagaccag ccgctgcccc ggtccgatcc acggcgaacc
    30901 aattgtgtcg ccagtctttg aacatgctcc atgatgatgc tctcgtactg gtttatagcc
    30961 gttgaagaga agccctggcc cactattcta cggcgctgtg cactttcttg agggtcagtc
    31021 atggtcaagg aacttggagc tcgatggacc atgacattgt acgttgtcga cttctgcaca
    31081 tgcttgttga atccgtatat ggcttgaaag ttggaatcag cattaccgca ttgtgtgagg
    31141 taggacggag aaaccccata ctacctttta gcccagtatt ggtgttcacc aaaagccgat
    31201 tcggagcata tctaacaaag tcacctgaag ggagcatgtc aggtttgtat atctgtgatc
    31261 acgacatgac gaatagcaaa ccgtattttt ggtgacatct ccacatgtca atgtgtaagt
    31321 ctccgctcca ggcatagtac gcgctgtaaa gattgctgat tcgtgccaac cacggacctg
    31381 gatatttcga cagcgggtgg aaccacagtc gatatataat catcgcttgg atctataaat
    31441 ataagcaaca cacatcggat tgaccagggt ataggaaaac gagcttacat agcctagaat
    31501 gagtgcagcc aaaacagtac aggtaacata aagtacttgc atgtcaatcg tagtcttcat
    31561 tttaggaact gaatagtgtg aatcctctgc tcatccagtg ccatggaagg cgaacctcgt
    31621 tggtacggta gaaactgaag accatgggct tatttgtatt gcacgggaaa gttcttccat
    31681 atcagtatca gagtggtgtt agttttcggg acgtttggcg ataactgaac ggcccgaatg
    31741 gacctatgtg tgtacacatt cacagattag agcttagtag cggaagttat aacaagccta
    31801 gatccagacc tgaaatggtt ttgtttacct actgaggcgg ccaatcctca actccaagtt
    31861 cagatccaag atcttcattc tccttctcac tgcaagatcc ggatccgttt tgccgagcct
    31921 gagcattcga catgaacgga aagagccgcg acaacggtca tgatgggaaa agacagcctg
    31981 tggtccccgc agagccaatt gcaatcgtcg gaacggcaat gaggctccca ggcgatgcag
    32041 cgaatcctag caagctatgg cagctgcttc gaaacccgcc atcagacctt tcacgtcgac
    32101 caccctccga gcgctttagc tcggccggat ttttccatga ggatccagaa catcatggga
    32161 caagtaacag tgagcaatct tactttctaa gggaggacat tcgagccttc gatgccgcat
    32221 tcttcagcat tgcgcctcgc gaagtcgaag ccatcgaccc ccaacatcga ctcttgctgg
    32281 aagttgttta cgaggccctt gaagctgccg gcattcccct ggagaagact cagggcagcg
    32341 atacggctgt gta
//
