BGC0001266 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001266 (Cladonia grayi)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	29,999	grayanic acid	PKS	100%

BGC0001266 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 29,999 nt. (total: 29,999 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 30,000
Label		BGC0001266

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001266	1.00	Polyketide	grayanic acid	Cladonia grayi
BGC0001258	0.36	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107	0.35	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001906	0.35	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001257	0.35	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.35	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0002154	0.35	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001284	0.35	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0001990	0.35	Other	BU-4704, xanthocillin-X monomethylether, melanocin E, melanocin F, fumiformamide	Aspergillus fumigatus Af293
BGC0000156	0.34	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001266	1.00	Polyketide	grayanic acid	Cladonia grayi
BGC0001258	0.69	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000107	0.68	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001906	0.68	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001257	0.68	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.68	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0002154	0.68	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001284	0.68	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0001990	0.68	Other	BU-4704, xanthocillin-X monomethylether, melanocin E, melanocin F, fumiformamide	Aspergillus fumigatus Af293
BGC0000156	0.67	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 29999:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

PKS16

PKS_AT (892..1195): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.9
Methoxymalonyl-CoA: 61.0
Methylmalonyl-CoA: 59.2
inactive: 57.2
Propionyl-CoA: 29.5
Ethylmalonyl-CoA: 22.2
2-Methylbutyryl-CoA: 22.1
Benzoyl-CoA: 19.5
Acetyl-CoA: 15.6
CHC-CoA: 15.3
Isobutyryl-CoA: 13.3
3-Methylbutyryl-CoA: 13.3
fatty_acid: 11.9
trans-1,2-CPDA: 10.5