BGC0001273 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001273 (Aspergillus ochraceus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	5,301	asperlactone	PKS	100%

BGC0001273 - Region 1 - T1PKS

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Location: 1 - 5,301 nt. (total: 5,301 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 5,302
Label		BGC0001273

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001273	1.00	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001275	0.38	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244	0.37	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001276	0.24	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0002229	0.23	Polyketide	6-MSA, aculin A	Aspergillus aculeatus ATCC 16872
BGC0000170	0.21	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0002615	0.20	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0000120	0.19	Polyketide	patulin	Penicillium expansum
BGC0001254	0.18	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002240	0.18	Polyketide	BAB, BAA	Metarhizium anisopliae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001273	1.00	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001275	0.70	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244	0.70	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001276	0.58	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0002229	0.56	Polyketide	6-MSA, aculin A	Aspergillus aculeatus ATCC 16872
BGC0000170	0.53	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0002615	0.53	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0000120	0.51	Polyketide	patulin	Penicillium expansum
BGC0001254	0.50	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002240	0.50	Polyketide	BAB, BAA	Metarhizium anisopliae

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 5301:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AAS98200.1

PKS_AT (566..859): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 103.5
Methoxymalonyl-CoA: 91.5
Ethylmalonyl-CoA: 80.3
Isobutyryl-CoA: 61.4
Malonyl-CoA: 56.2
Propionyl-CoA: 45.9
trans-1,2-CPDA: 39.6
2-Methylbutyryl-CoA: 34.8
Benzoyl-CoA: 34.6
3-Methylbutyryl-CoA: 33.8
Acetyl-CoA: 33.2
fatty_acid: 21.7
CHC-CoA: 14.5
inactive: 8.8