BGC0001278: T-2 toxin biosynthetic gene cluster from Fusarium sporotrichioides
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Location: 1 - 54,488 nt. (total: 54,488 nt).
This entry is originally from NCBI GenBank AF359360.3, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001278
Short description T-2 toxin biosynthetic gene cluster from Fusarium sporotrichioides
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
AF359360.3
via
Compounds
  • T-2 toxin
Species Fusarium sporotrichioides [taxonomy]
References
Chemical products information
T-2 toxin [synonyms: T2 toxin, T-2] Evidence: Mass spectrometry [1]
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C24H34O9
Chemical database entries
ChEMBL
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO27746.2
  • OrfF
 589 - 1760 (+) putative methyltransferase
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    • AAO27747.1
    • OrfE
    		 2131 - 3198 (-) unknown
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      • AAO27748.1
      • OrfD
      		 4962 - 8121 (+) unknown
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        • AAO27749.1
        • OrfC
        		 8300 - 9260 (-) glucosidase
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          • AAO27750.1
          • OrfB
          		 10782 - 11555 (+) esterase
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            • AAO27751.1
            • OrfG
            		 12093 - 13209 (-) monooxygenase
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              • AAK33077.1
              • TRI8
              		 15488 - 16831 (-) Tri8
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                • AAK33076.1
                • TRI7
                		 17529 - 18907 (+) Tri7
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                  • AAK33072.1
                  • TRI3
                  		 19674 - 21456 (+) 15-O-acetyltransferase
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                    • AAK33073.1
                    • TRI4
                    		 22222 - 23964 (-) cytochrome P450
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                      • AAK33075.1
                      • TRI6
                      		 25123 - 25776 (+) positive regulatory protein
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                        • AAK33074.1
                        • TRI5
                        		 28080 - 29264 (+) trichodiene synthase
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                          • AAK33069.1
                          • TRI10
                          		 29881 - 31220 (+) putative trichothecene biosynthetic gene
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                            • AAK33078.1
                            • TRI9
                            		 31851 - 31982 (-) TRI9
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                              • AAK33070.1
                              • TRI11
                              		 33069 - 34790 (-) trichothecene C-15 hydroxylase
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                                • AAK33071.1
                                • TRI12
                                		 35435 - 37336 (-) trichothecene efflux pump
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                                  • AAN40834.1
                                  • TRI13
                                  		 38106 - 39938 (-) cytochrome P450
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                                    • AAN40835.1
                                    • TRI14
                                    		 40706 - 41881 (+) unknown
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                                      • AAO27752.1
                                      • OrfG_rename1
                                      		 42580 - 43337 (-) deacetylase
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                                        • AAO27753.1
                                        • OrfH
                                        		 44960 - 46803 (+) unknown
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                                          • AAO27754.1
                                          • OrfI
                                          		 47603 - 48460 (-) dehydrogenase
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                                            • AAO27755.1
                                            • OrfJ
                                            		 49404 - 50824 (-) reductase
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                                              • AAO27756.1
                                              • OrfK
                                              		 51884 - 53437 (+) monooxygenase
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                                                • AAO27757.1
                                                • OrfL
                                                		 53727 - >54488 (+) catalase
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                                                  Biosynthesis information
                                                  Annotation changelog

                                                  Entry version: next

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2024-05-27
                                                  MIBiG v4 annotathon
                                                  • (ID: D44UGPXERIZAXNCG2VXZP5I3)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 3

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-09-15
                                                  Cleaned up synonym list
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Migrated from v1.4
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  2019-10-16
                                                  Updated compound(s) information (MIBiG Annotathon)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2015-12-24
                                                  Submitted
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  Similar known gene clusters from MIBiG 4.0
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                                                  Modifications to original record
                                                  • renamed CDS with name OrfG at join{[43032:43337](-), [42579:42967](-)} to OrfG_rename1 to avoid duplicates