Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001283.1:
Cluster 1Other132355

BGC0001283, arsenopolyketides biosynthetic gene cluster from Streptomyces lividans. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Arsono-polyketide
Molecular formula: C15H28AsO3
Exact molecular mass: 331.1248 Da (M+)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
Other

Gene cluster description

arsenopolyketides (BGC0001283). Gene Cluster 1. Biosynthetic class = Other. GenBank NZ_CM001889, positions 1079702-1113162. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Gene expression correlated with compound production, Sequence-based prediction
MIxS-compliance:Unknown
Comments:The actual structures of these products are still subject to further investigation and will be discussed in detail in a future publication.
Contact for this cluster:Pablo Cruz-Morales (Laboratorio Nacional de Genomica para la Biocidersidad (CINVESTAV-Langebio))

Literature references

1. Cruz-Morales P et al. (2013 TI) The genome sequence of Streptomyces lividans 66 reveals a novel tRNA-dependent peptide biosynthetic system within a metal-related genomic island. Genome Biol Evol 5(6):1165-75. doi: 10.1093/gbe/evt082.
2. Cruz-Morales P et al. (2016) Phylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model Streptomycetes. Genome Biol Evol 8(6):1906-16. doi: 10.1093/gbe/evw125.