MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 100.0 100.0 478.0 1.33e-173
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 57.0 93.0 234.0 3.34e-77
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 47.0 96.7 196.0 1.47e-62
OEI73917.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 42.0 93.4 175.0 1.67e-54
NII05595.1 heavy_metal_response_regulator_transcription_factor BGC0003005.1 NRPS:Type I 44.0 92.6 172.0 3.78e-53
OEI75232.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 42.0 96.7 171.0 7.61e-53
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 43.0 93.8 168.0 9.34e-52
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 43.0 94.6 167.0 3.73e-51
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 43.0 94.6 167.0 3.73e-51
OEI76711.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 40.0 95.9 165.0 1.68e-50
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 41.0 97.5 162.0 1.83e-49
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 43.0 93.8 160.0 8.95e-49
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 40.0 91.3 157.0 2.01e-47
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 43.0 92.6 157.0 2.53e-47
AFI57015.1 QmnRg3 BGC0000133.5 PKS 41.0 91.7 154.0 1.85e-46
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 41.0 97.5 155.0 2.63e-46
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 40.0 95.0 153.0 6.19e-46
QCT05734.1 Tri1 BGC0001983.3 other:other 40.0 91.7 150.0 8.99e-45
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 38.0 95.5 148.0 5.65e-44
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 39.0 93.0 146.0 4.23e-43
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 36.0 95.5 144.0 4.52e-42
AQZ69221.1 DNA-binding_response_regulator BGC0001635.4 NRPS:Type I+PKS 41.0 90.9 139.0 1.12e-40
AVO00817.1 May18 BGC0001661.5 PKS 38.0 95.9 136.0 2.13e-39
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 39.0 93.4 137.0 2.32e-39
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 41.0 90.9 136.0 2.48e-39
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 43.0 92.1 135.0 3.5e-39
MCC5036779.1 response_regulator_transcription_factor BGC0002638.3 NRPS:Type I 40.0 90.9 135.0 4.94e-39
OEI76576.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 35.0 93.4 135.0 9.12e-39
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 38.0 92.6 134.0 2.42e-38
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 37.0 94.2 134.0 2.49e-38
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 37.0 96.3 134.0 2.74e-38
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 37.0 96.7 134.0 3.6e-38
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 38.0 93.0 134.0 3.66e-38
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 38.0 93.0 134.0 3.66e-38
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 42.0 92.1 134.0 3.79e-38
UYO79789.1 BalReg1 BGC0003038.1 PKS:Type II aromatic 38.0 92.6 133.0 4.21e-38
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 38.0 93.0 134.0 4.26e-38
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 37.0 95.0 132.0 7.55e-38
OEI72873.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 94.6 131.0 2.17e-37
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 36.0 94.6 131.0 2.89e-37
QYC40300.1 Response_regulator BGC0002344.2 NRPS:Type I 40.0 90.9 130.0 3.05e-37
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 38.0 92.6 131.0 7.05e-37
ADI71440.1 putative_transcriptional_regulator BGC0000203.3 PKS 40.0 94.6 130.0 7.49e-37
AOT85897.1 response_regulator BGC0001788.3 ribosomal:RiPP 37.0 93.0 130.0 9e-37
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 38.0 96.3 129.0 1.08e-36
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 40.0 95.9 129.0 3.19e-36
AGF91744.1 response_regulator BGC0003168.1 NRPS:Type I+saccharide 37.0 93.8 128.0 3.45e-36
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 38.0 93.0 128.0 3.92e-36
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 36.0 91.7 128.0 4.74e-36
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 36.0 90.9 127.0 6.01e-36
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 36.0 90.9 127.0 6.01e-36
CAD91201.1 putative_response_regulator BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 39.0 90.9 126.0 1.33e-35
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 36.0 90.9 126.0 1.91e-35
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 37.0 96.3 127.0 4.27e-35
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 37.0 97.1 125.0 7.31e-35
CAB93669.1 RumR_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 35.0 93.0 125.0 7.89e-35
ABI30224.1 McdR BGC0000526.5 ribosomal:RiPP:Lanthipeptide 33.0 94.2 124.0 1.08e-34
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 35.0 96.3 124.0 2.31e-34
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 36.0 95.9 124.0 2.6e-34
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 36.0 96.3 124.0 7.22e-34
EKB09395.1 hypothetical_protein BGC0003104.1 ribosomal:RiPP:Lanthipeptide 34.0 93.4 122.0 1.1e-33
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 34.0 92.1 120.0 2.43e-33
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 36.0 90.9 118.0 1.75e-32
CAA60455.1 response_regulator BGC0001040.5 NRPS:Type I+PKS 39.0 92.1 118.0 1.89e-32
ACX68642.1 SivR BGC0000547.5 ribosomal:RiPP:Lanthipeptide 33.0 94.2 115.0 3.87e-31
OEI75709.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 100.4 115.0 4.03e-31
OEI75686.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 94.2 115.0 4.59e-31
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 32.0 93.0 114.0 1.51e-30
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 29.0 93.4 111.0 1.62e-29
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 28.0 91.3 110.0 1.75e-29
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 30.0 93.8 110.0 2.07e-29
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 29.0 93.8 109.0 8.05e-29
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 37.0 87.6 108.0 1.8e-28
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 93.4 108.0 2.44e-28
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 37.0 93.4 107.0 3.58e-28
EFV97036.1 nisin_biosynthesis_regulatory_protein_NisR BGC0003095.1 ribosomal:RiPP:Lanthipeptide 29.0 93.4 107.0 4.8e-28
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 30.0 93.8 103.0 7.64e-27
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 41.0 50.0 101.0 1.04e-26
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 30.0 91.3 103.0 1.5e-26
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 30.0 93.8 102.0 2.95e-26
QCP68977.1 response_regulator BGC0002296.2 NRPS:Type I+PKS 44.0 50.0 103.0 5.74e-25
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 27.0 93.8 98.0 1.43e-24
ACV42481.1 putative_adenylate/guanylate_cyclase BGC0000043.5 PKS 42.0 50.0 100.0 1.65e-23
OEI75846.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 31.0 94.6 96.0 1.8e-23
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 43.0 52.5 92.0 4.57e-23
OEI72827.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 27.0 92.1 92.0 2.74e-22
QXJ26481.1 response_regulator BGC0002370.2 NRPS:Type I 39.0 50.8 89.0 4.72e-22
AFB74478.1 putative_response_regulator BGC0000550.3 ribosomal:RiPP:Lanthipeptide 40.0 50.8 89.0 1e-21
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 35.0 52.1 92.0 1.68e-21
BAB08160.1 SrtR BGC0000556.5 ribosomal:RiPP:Lanthipeptide 25.0 93.8 88.0 8.47e-21
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 37.0 65.3 86.0 1.41e-20
QDA77064.1 multi-sensor_hybrid_histidine_kinase BGC0002026.3 NRPS:Type I+PKS 38.0 50.8 82.0 1.64e-17
WP_091320338.1 HAMP_domain-containing_protein BGC0002007.2 terpene 38.0 56.2 82.0 2.05e-17
OEI76008.1 histidine_kinase BGC0002977.1 NRPS:Type I+PKS:Type I 36.0 50.0 75.0 4.43e-15
ADB02831.1 AzicR2 BGC0000202.5 PKS 30.0 76.9 70.0 4.53e-14
UUG66832.1 Plx29 BGC0002939.1 NRPS:Type I 34.0 51.2 72.0 7e-14
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 37.0 52.5 71.0 8.22e-14
OEI76089.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 49.6 65.0 3.81e-13
ABK32275.1 Amb7 BGC0000014.5 PKS 34.0 50.4 69.0 4.4e-13
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 35.0 49.6 67.0 5.34e-13
ABK32300.1 Jer7 BGC0000080.5 PKS 33.0 50.4 68.0 1.07e-12
ABK32284.1 Jer4 BGC0000080.5 PKS 32.0 49.6 67.0 1.89e-12
ABK32252.1 Amb4 BGC0000014.5 PKS 32.0 49.6 67.0 2.55e-12
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 34.0 58.7 64.0 6.87e-12
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 34.0 53.3 64.0 7.45e-12
OEI74226.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 29.0 51.7 61.0 9.45e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 31.0 62.4 63.0 1.25e-11
UUG47293.1 DNA-binding_response_regulator BGC0002932.1 PKS:Type II aromatic 28.0 93.8 61.0 5.82e-11
OEI74806.1 sporulation_transcription_factor_Spo0A BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 52.1 61.0 1.21e-10
WMD04184.1 response_regulator_transcription_factor BGC0002988.1 PKS:Type I 33.0 53.3 60.0 1.79e-10
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 32.0 50.0 60.0 1.79e-10
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 35.0 53.3 59.0 2.61e-10
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 32.0 61.6 59.0 2.64e-10
AXA91286.1 hybrid_sensor_histidine_kinase/response_regulator BGC0002044.2 NRPS:Type I 32.0 54.1 61.0 3.6e-10
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 28.0 97.1 59.0 3.86e-10
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 34.0 50.4 58.0 7.14e-10
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 30.0 69.4 58.0 7.37e-10
AXI91558.1 FunR5 BGC0001944.2 PKS 30.0 86.8 58.0 8e-10
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 26.0 94.6 57.0 1.78e-09
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 28.0 95.0 57.0 1.82e-09
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 26.0 86.4 57.0 2.43e-09
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 29.0 52.9 56.0 3.24e-09
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 30.0 62.4 54.0 1.63e-08
OEI76130.1 histidine_kinase BGC0002977.1 NRPS:Type I+PKS:Type I 32.0 50.4 55.0 2.15e-08
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 29.0 50.8 54.0 2.83e-08
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 28.0 62.0 54.0 2.88e-08
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 29.0 50.8 53.0 3.84e-08
AQW35080.1 two-component_response_regulator BGC0001675.5 PKS 28.0 66.1 53.0 4.06e-08
AQP25560.1 luxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 28.0 77.3 53.0 5.18e-08
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 31.0 55.4 53.0 5.42e-08
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 55.0 52.0 8.07e-08
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 28.0 65.7 52.0 9.31e-08
BBD82049.1 LuxR_family_transcriptional_regulator BGC0002986.1 ribosomal:RiPP:Lasso peptide 26.0 95.5 52.0 1.36e-07
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 29.0 50.0 51.0 1.81e-07
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 27.0 59.9 50.0 3.06e-07
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 26.0 95.5 50.0 3.39e-07
OEI73132.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 25.0 51.2 50.0 4.19e-07
ABD65961.1 two-component_system_response_regulator BGC0000341.5 NRPS:Type I 29.0 86.0 50.0 6.18e-07
UUG66853.1 Plx28 BGC0002939.1 NRPS:Type I 27.0 49.2 49.0 6.61e-07
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 30.0 53.3 49.0 1.13e-06
OEI73534.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 51.2 47.0 6.56e-06