BGC0001304 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001304 (Aspergillus flavus NRRL3357)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	15,094	aflavarin	PKS	100%

BGC0001304 - Region 1 - T1PKS

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Location: 1 - 15,094 nt. (total: 15,094 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,095
Label		BGC0001304

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001304	1.00	Polyketide	aflavarin	Aspergillus flavus NRRL3357
BGC0000156	0.36	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001284	0.35	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0002154	0.35	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0002175	0.35	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0001258	0.35	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001266	0.35	Polyketide	grayanic acid	Cladonia grayi
BGC0001257	0.35	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107	0.34	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001906	0.34	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001304	1.00	Polyketide	aflavarin	Aspergillus flavus NRRL3357
BGC0000156	0.68	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001284	0.68	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0002154	0.68	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0002175	0.68	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0001258	0.68	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001266	0.68	Polyketide	grayanic acid	Cladonia grayi
BGC0001257	0.68	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107	0.67	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001906	0.67	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15094:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AFLA_108550

PKS_AT (910..1208): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 68.9
inactive: 44.8
Methoxymalonyl-CoA: 42.2
Methylmalonyl-CoA: 33.9
Ethylmalonyl-CoA: 18.1
fatty_acid: 17.6
Propionyl-CoA: 16.8
2-Methylbutyryl-CoA: 14.5
3-Methylbutyryl-CoA: 12.5
Acetyl-CoA: 12.2
Benzoyl-CoA: 12.0
Isobutyryl-CoA: 11.1
CHC-CoA: 9.7
trans-1,2-CPDA: 0.0