Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001308.1:
Cluster 1Polyketide127781
The following clusters are from record BGC0001308.2:
Cluster 2Polyketide116796

BGC0001308, simocyclinone D9 / simocyclinone D10 / simocyclinone D11 biosynthetic gene cluster from Streptomyces sp. NRRL. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: simocyclinone D9

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type II

Gene cluster description

simocyclinone D9 / simocyclinone D10 / simocyclinone D11 (BGC0001308). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank NZ_JOAI01000014. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Bilyk O et al. (2016) New Simocyclinones: Surprising Evolutionary and Biosynthetic Insights. ACS Chem Biol 11(1):241-50. doi: 10.1021/acschembio.5b00669. Epub

BGC0001308, simocyclinone D9 / simocyclinone D10 / simocyclinone D11 biosynthetic gene cluster from Streptomyces sp. NRRL. Locus 2. Partial MIBiG entry.

Chemical compounds

Compound: simocyclinone D9

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type II

Gene cluster description

simocyclinone D9 / simocyclinone D10 / simocyclinone D11 (BGC0001308). Gene Cluster 2. Biosynthetic class = Polyketide. GenBank NZ_JOAI01000008. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Bilyk O et al. (2016) New Simocyclinones: Surprising Evolutionary and Biosynthetic Insights. ACS Chem Biol 11(1):241-50. doi: 10.1021/acschembio.5b00669. Epub