LOCUS       BGC0001334             20777 bp    DNA     linear   BCT 04-NOV-2013
DEFINITION  Streptomyces uncialis putative RibD domain-containing protein,
            putative transcriptional regulator, hypothetical protein, putative
            integral membrane protein, hypothetical protein, putative secreted
            protein, hypothetical protein, putative transcriptional repressor,
            and putative transporter genes, complete cds; cladoniamide gene
            cluster, complete sequence; hypothetical proteins and putative
            transcriptional regulator genes, complete cds; and extracellular
            solute-binding protein gene, partial cds.
ACCESSION   BGC0001334
VERSION     BGC0001334
KEYWORDS    .
SOURCE      Streptomyces uncialis
  ORGANISM  Streptomyces uncialis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:21:18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20777
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..1542
                     /gene="claH"
     CDS             1..1542
                     /codon_start=1
                     /gene="claH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 39.5; E-value: 6.4e-12)"
                     /gene_kind="biosynthetic-additional"
                     /product="halogenase"
                     /protein_id="AEO12707.1"
                     /sec_met_domain="Trp_halogenase (E-value: 8.5e-145,
                     bitscore: 472.7, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2.2e-11, bitscore: 33.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLESIVVVGGGTSGWMTASYLSAAFGERISVTVVESARVGTIGVG
                     EATFSTVRHFFEYLGLSEETWMPACNATYKLGIRFENWRAPGHHFYHPFERQRVVDGFT
                     LPDWWLADGGATERFDKECFLVGTLCDTMRSPRHMDGALFEGDLTDRPAGRSTLAEQGT
                     QFPYAYHFDAALLADFLRDYAVARGVLHVVDDVVHVARDERGWISHVATRGSGDLAGDL
                     FVDCTGFRGLLINDALDEPFESYQDTLPNDSAVALRVPVDMEREGLRPCTTSTAQAAGW
                     IWTIPLFGRVGTGYVYARDYCTPEEAERTLRRFVGPAADDLEANHIRMRIGRSRRSWVN
                     NCVAVGLSSGFVEPLESTGIFFIQHAIEQLVKHFPDADWDPALRSAYNTLVNRCMDGVR
                     EFLVLHYYGAARADNEYWRDTKTRKIPDSLAERVEQWRTKLPHPESVYPHYHGFEAYSY
                     VCMVLGLGGIPLKPSPALRMLDPSAAQREFRLLATQAEDLRRTLPSQYAYFAQFR"
     misc_feature    1..20777
                     /note="cladoniamide gene cluster"
     subregion       1..20777
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001334"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..20777
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="indole"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1567..2835
                     /gene="claT"
     CDS             1567..2835
                     /codon_start=1
                     /gene="claT"
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 214.1; E-value:
                     4.8e-65)"
                     /gene_kind="transport"
                     /product="antiporter"
                     /protein_id="AEO12708.1"
                     /transl_table=11
                     /translation="MTIDLLWSVLHLTALLGALGLVALTGRAVARWLRLPLVIGEILVG
                     LCAGPALLALLGGPGFDRLLPDHLAVPLARVGEAGLVLFLVGVVHGLRHGPAGPANRAL
                     GRVSAGVFLLPLLTGLLFAGWVLWLGPPGLAGTAPLPALLVMLPVAMSVTAVPVLACVI
                     DERGPGLGRAAPLALMSAILLDTVAWLLLAVALGLAAGGLWGVAGAFAALAVGLLLAHG
                     GRRALARPRITAAAARRPTAAAVLLGGLALLAATGAHGAGLTAVLGAFLAGVMVPHDPD
                     GPWTRAVAVVARVGRVLLPVFFVGTGITLFTESAGSLPWSATLLCTALAIVGKVGGGYL
                     GALWAGEDRRTALRVGVLVNTRGLTEIVVLQVGWAAGILTPGLFLAMLVMALVTTVLTG
                     PLLSLIDHHAASREPLVRTGGVP"
     protocluster    1942..20777
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[11941:15214]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11942..15214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     cand_cluster    1942..20777
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     gene            2832..3365
                     /gene="claF"
     CDS             2832..3365
                     /codon_start=1
                     /gene="claF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 110.8; E-value: 8.6e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin reductase"
                     /protein_id="AEO12709.1"
                     /transl_table=11
                     /translation="MKLSPEITPTRFRALMAGFPSGVAVLTATDPDGGRPWGMTCSSVC
                     AVSLAPPTLLVCVRTGSPTLDAMLRRSAFAVNLLHDGARATAELFASGAPHRFDQVRWE
                     YPVTGGGPHLVEDAHTVADCEVSGHQVVGSHAVVFGEVTAVHHRSPPRPLLYGLRRYAA
                     WPLPDVDTVSWVAP"
     gene            complement(3539..4375)
                     /gene="claY"
     CDS             complement(3539..4375)
                     /codon_start=1
                     /gene="claY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /product="putative alpha/beta hydrolase"
                     /protein_id="AEO12710.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.6e-09, bitscore:
                     27.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.1e-08, bitscore: 22.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDATLPANPPDTGAEVLVRTHDGLRLAGTLLVPPGHHDGSRDAA
                     LFLHGSGADREQGGLFTRVARGLADGGVATLRFDLPGHGHSEGRQAELSLSGLLNLIGS
                     GLRELRERTGAARIAVLAAGLTGGVAAGYAARRGDEIGRLVLFDPLIDYQEHFTADSPR
                     WRGGRLTEPAGRTLLADGALASACGLAAGRAMLNEVFWLQPRGVLGAVTAPTLIVHGTG
                     AARVPVASSRSAAGALTAEHRLVELPPGGDALAGAVSAALAWLLPAATDAGDDAPG"
     gene            4717..6276
                     /gene="claO"
     CDS             4717..6276
                     /codon_start=1
                     /gene="claO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /product="amino acid oxidase"
                     /protein_id="AEO12711.1"
                     /sec_met_domain="DAO (E-value: 5.9e-11, bitscore: 32.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRNGSAATGVTRPYPPLSTIPRPPASAGHPPPGPKRITVVGAGI
                     AGLIAAHELERLGHRVQVLEAGLAPGGRVRTHGFSGRAHGPLVELGAMRIPASHHLTMQ
                     WIDRLRLSDRVRQFRTLFSDDASYLATPAGHVRVRDASPVLVEEFRRSLPPGPDHRPET
                     LLCAAWLAASVHAVAPGTFGRGLHTDLPVELLGLLAGIDVRPYLVGGAATRIDLNRFFA
                     HHQGFAAHGRFRYFFDDVVTETSSALFRLDGGMDQIPRRLVAQLRGPVRWGRRVVGLHA
                     RPDGVTVDTRHGLSTERFDCPYVLCTLPFSVLRRMPLTGVGDDKTAVVNDMQYWPATKI
                     ALHCREAFWENDGISGGGSFTGGLTRQTYYPPVESDPRLGAALLASYTIGPDAEALSEV
                     PKDKRVATVLGELKPMHPELASPGMLLDARSQVWGEDPLSMGAASVRWSKDPDTAEEER
                     RLAAAPQGALFFAGEHCSSTPAWIEGAIESGLTAAREIHGHVPLNRGVTAPGHRVGAGG
                     AR"
     gene            6318..8003
                     /gene="claC"
     CDS             6318..8003
                     /codon_start=1
                     /gene="claC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 338.3; E-value:
                     1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin monooxygenase"
                     /protein_id="AEO12712.1"
                     /transl_table=11
                     /translation="MNPSHDTGVLIVGGGPTGMATGLELRSRGVDFTLVEAGDGSVTHP
                     KVSAIGPRSMEFFRRWGMADRVRGAGWPGDHTLDCVWVTRVGGHELYRLPRRTMDTRAP
                     FRHTPEPDAICPQHWLGPLLREELGVHPGGPVRMRTRMTGFTQDADGVTARLTDEATGR
                     TTTLRARYLIACDGTSSQVRKDAGIEAPARHRTRVCRNILFRAPRLREELGERNANFFY
                     LLMSSALRFPLRALDGKDLYRLTVGLLGHPDSLVDAETLVRRAIAHDTPVEVLSDNQWH
                     LVHRVAENFRADRVFLVGDAAHTLSPSGGFGMNTGICGAADLGWKLAAAFDGWAGPGLL
                     DSYTTERRPVALEGLEEANRHLVRAWAREIPGELNDDTPEGERHRRSLGADLAAGPVAK
                     EFDAPEIHLGFSYADSPLVVPDPTVPADAHDDRRPNSRPGSRAPHAWVKPGTSTLDLFG
                     DGFVLMSSTRSARTDGFTRAFADRRVPLTVVHCEVPEVVESLERPFVLVRPDGHVAWRG
                     HELPDDPAAVAARVTGAGTGTGTGTRAGTGTDSGTGASGTGGAP"
     gene            8000..9262
                     /gene="claP"
     CDS             8000..9262
                     /codon_start=1
                     /gene="claP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 357.2; E-value:
                     1.8e-108)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="AEO12713.1"
                     /sec_met_domain="p450 (E-value: 1.8e-18, bitscore: 56.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPATAPAALPPFGLTGWPAERLADPYPVYRRYRAAARVHRAEPD
                     GTAPTFYVLGHDEVAKVLSAPVYGRSPRRATGGAPPATVPNGHSALRSMVENWLVFLDP
                     PRHTELRSLLNREFTPGVVTDLRGRIQDIAVGLLAELTAEAARTGTVDLVERFSAPFPI
                     LVISELLGVDRTDWAWLREQAVGVQQASSSRAALRPDAHHVAETAARELTSYFLELAAR
                     RRAEPAADLVSLLVSAQTRGEPLTDAEIVATCVHLMTAGHETTTNVLSKSVLTLTARPA
                     QLARLRAAPLVPAPAVEELVRFDPPVQAVTRWAYRDVVLGGHHVPRGSKLFAVLGAANR
                     DPARFPDPDTLDLDRGGRNLAFGLGVHYCLGAGLARTEIEIGLGLLLRALAALGDSEVD
                     EVHYPYDLVFHGPERLTLRLR"
     gene            complement(9243..10904)
                     /gene="claX1"
     CDS             complement(9243..10904)
                     /codon_start=1
                     /gene="claX1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 376.9; E-value:
                     2.9e-114)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin monooxygenase"
                     /protein_id="AEO12714.1"
                     /transl_table=11
                     /translation="MRDAHDCDVLVVGAGPSGLTAALALAQQGVRVRVVDRAAGPVEEA
                     RAAIVHARTLELLDRLGVAAQAVARGLPITQVAIHERGRHAGRMPLAGAGTAAWTRFPY
                     ALALEQFETQRLLVEALAEHAVDVEWDSALDSLADTGEGVRVTVRRTDGEETVTARWLI
                     GADGASSTVRQSLGLEFGGRTYPQSGMLADVVLDADLGVRGMRLNLTRGGFVGILPLAS
                     GRCRLFGVVPPSVHKAQEPVETSHEAYAALEPEVLHRWFADYFRVDARLQEIVWASMFR
                     FHSRIAPRFRVGSCFLIGDAAHIHNPAGGQGLNLGVGDAVNLAWKLAQVVHGQAPPWLL
                     DTYESERRPIARTVLKRTDLGFRAETGDGAVAVWMRTQVAARVVGVVSRLAPVRRMFFH
                     MFSQLWIGYRGSRAVAAARPVTGGLRPGDRAPYALLARAGDGTGSVLDLTHGSGYHVLG
                     FAADPGAAGLDVQELAELLDDRYPGMVTVHAVPPQETAAYRAYQVKGARLVVVRPDGHL
                     GAVVDLPAPDAVGALVAFLDRVLLRATSPEVSAAAG"
     gene            11214..11945
                     /gene="claM1"
     CDS             11214..11945
                     /codon_start=1
                     /gene="claM1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 101.5; E-value:
                     8.6e-31)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="AEO12715.1"
                     /sec_met_domain="PCMT (E-value: 1.8e-07, bitscore: 20.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQAPVPPPPQPYFDDLADLYERFTSIRDGATSPVRSWLVGQLP
                     KGQRALDIGCGGGNNCVMLAERYDEVVGVDISRRMLDIAAAKPARVPVRYQHRSALDLT
                     PAADGTFDLVMSVNAVFHLGPAPRVLPRLRDLVAPGGRLVVIDVTRPDATGTDTDAAPP
                     AERDTYAFDTARTIYEVSGDADAAADSLRMMLHPRWLEMSAAHMPLTYGEFVRAYREQL
                     PGVRITRDLIPTMSAAVWDAP"
     gene            11942..15214
                     /gene="claD"
     CDS             11942..15214
                     /codon_start=1
                     /gene="claD"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /product="chromopyrrolic acid synthase"
                     /protein_id="AEO12716.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1304.8,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLDVPRVHFAGAAVTRLPTGPRSGLYDLATGRALTDDGPFPLE
                     RPAREYHDLLRARGERYEPDGTLTPDGRFSTTTGWNFGGNGHFWIDARVTGCEHTPGRA
                     ATDDPLVGRAVDLWGHFCDYTAGTVNRCRVLDVDPASPWTTTVMIGQLALGRLGRSHDV
                     GYLLTGDVTGMSPPRWPNARYIDDVGPHPLADRFRRSVVHQFAVERGTGLHWLDGSADS
                     PALTALRDLLDSGAADGLVVQLALSNMSTPTDNDQPDFWDLRGVLAPWHAHELRTYPAG
                     RLLTGRRVRAAGHHAPLHNLTVRVDDEHVTANLVTALPVTGRAPLRGPGPTHRTGPLAD
                     LGDLQLRAADGTLVAVVRGADYLGAGYRRTGGLLTLDRIDGRTGEPAGPLRITSPDGTV
                     LADEEETVVQSDEAALFLEHPNPRTGEDFAVQVPVRSYVRGRPARATGIRVQQYPNPRA
                     LPLDPAAQSPDARPADIPVTAFLAPGRADYTADSLLSTDEHGHGTLTLRGAAAGAALVL
                     LLPAGEQPPADPAEPGSAARGYDHDDDLGYWPAAGSIAVRVLPDHWHLDDLPDSAITFP
                     LVYRQALAPYELLYSFMSDEVLSLADEFKVETYARLIWHVSAPEHRDRTFYMPSTRDLS
                     APQIRLLLRYMLADEAKRQTPPVLVPPHRTPGTITTRDALLRALRQAAAIELATMIQYL
                     YAAYSVPTHGAARHYVERGEWTPAQLLLACGEGPQTLSNGIRGSLTNVAREEMMHFLAI
                     NNILMAMGAPFQVPDIDFGTFNHRIDVPLEFSLEPLGLGSVQRFIALEQPHTLTQEIAG
                     NDSTADGGTAYRYGSLSELYAAIRDGIQRVPGAFLVRKGRGGGEHHLFMRESVNAVHPD
                     YQLEVDDVTSAVFAIDFVTEHGEGGSIPSVLPDEDSHFDTFLRISDALVHERAQGPNGR
                     AVPWNPAYPVLRNPTLDLRSTAKDPVTHEPARRAMTVFNRSYALAMHLMVQHFGHSPDK
                     SLRRSRLMNWALDIMTGVLRPVAELVVTLPSGRPGRTAGPSFELGTVPQYIARPDVAAA
                     WLAREFDETASLARGCPALTPAVADLLAFIGDRLRTMDPREM"
     gene            15214..16479
                     /gene="claX2"
     CDS             15214..16479
                     /codon_start=1
                     /gene="claX2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 215.4; E-value:
                     2.7e-65)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin monooxygenase"
                     /protein_id="AEO12717.1"
                     /transl_table=11
                     /translation="MSGPAPTRTTVCVVGGGPAGAMLGLLLARSGVDVVVLEKHHDFHR
                     DFRGDTVHPATLRVLDQLGLIDRFHALPHQKVTTIGVIQDGHRIDIADFSRLRVPYPYM
                     AFVPQWDFLDLITAESARHPAYRLLMGTAATGVLRDTDGRVSGVRTRGPDGAADLRCAL
                     VVAADGRHSALRAAVGARPKLIGSSLDVGFFRISRRPTDPDEGICVRVGNGKIFGATDR
                     GTYWQMSYETTRGGFDRVRHAGLDAFRADLAALVPFLADRVHELRSLDDISLLEARIDR
                     LARWHRPGLLFIGDAAHAMSPVAGFGVNLAVQDAVATANALCAPLLRAQRTGAAFDDSL
                     LTKVRRRRLVATALSQGLQRATQRFGIDTTLNGSGQPPAPRLFERFRPAQLLMSRVIGV
                     GFRPEHIRTPPARPADHEKDPT"
     gene            16476..17510
                     /gene="claM3"
     CDS             16476..17510
                     /codon_start=1
                     /gene="claM3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 293.2; E-value:
                     4.3e-89)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="AEO12718.1"
                     /transl_table=11
                     /translation="MSAADPGGTGPAPADRMMSMITGYWVTQIVRTVAELSIPDQLAEG
                     PLTAAELAARIDADPDAVARLLRACASLGLTEADDRRAFHRTPLLDTLRAGTPHSLRTI
                     ALVHGSPGHWLPWGLLPDAVRSGTPQTGAALGRDIWAHFLAHPEEGERFATSMTELTAG
                     LAEEVAALIDTDGVGVAVDVGGANGALVHALLRGDPRPRGVVVDLPAVEESARAEAREA
                     GLADRVTVVGGSFFDPLPRGDLFLLKAVLHNWDDDACTAILRNCRAALNPGGRVIVVEM
                     PLGPLGEPGFAPLLDLNMLAVLPGRERDLPHYDALFAAAGLRRTGITPTRSPQRLITAV
                     TAGS"
     gene            complement(17832..20777)
                     /gene="claR"
     CDS             complement(17832..20777)
                     /codon_start=1
                     /gene="claR"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 122.2; E-value: 3.6e-37)"
                     /gene_kind="regulatory"
                     /product="transcriptional regulator"
                     /protein_id="AEO12719.1"
                     /transl_table=11
                     /translation="MNGKTLEKPDDPVPQFPPAVGRPLRGRDGHLEQIRASLRATAESR
                     QGGITLLESPAGSGRTRLLQETGALAEGLGFTVIDCSAGGAWRGEEAASPAVGAGRAVA
                     PRVPRPVRPAGPVQVQAQIDAGLRRGPVLVLVDDAQWADPVQLRTLCGLALKLLAAPVR
                     WLLTMRTEDARSANSLLLRNLTIHRAEWLPQLDALDDRAVTELMGDLLGARPSDDVRAL
                     GESLGGSPQAIVELVRGLLDEQCLRITGGTVSLVAEPLASGFTSAVAPDPGAHLPRAFL
                     RLMHDRLDRLAPGTQRLLQVAAVLGPSFMPRDLAEMADERPVQLLGPLQESLAAGLLTS
                     GTEEFSFHREPIWYAVLGTVPPLMRSLLHRQAANMILGQLGDGTAAAVHLVHCAQSDDD
                     QAITTIREAADRLLPVSPQAAAALALRGLEITTPTQPEHIALATTATAALVRSGSLHRA
                     VDVAERVVAGHRRAHPARPGDGARQDARTWPLRAWLATALLLRGEAASVPGILCDAAAG
                     GPPDPAADGAGPGQGSPSPLLLRLTMLSHTDERAALAAADEVLKDESAHERDVCTAARN
                     IRAMSLWGDGRIDESLGLLERTPAHGDDGTGIWQNNSLWNTAWILIKLRDLDGAAVMVE
                     AVRRTIDADSNGVLDPLQFALRSWVSFARGDLAEAEQLARAGITASDAARMPLCEPHLR
                     AVLVAVALRRGDLAEALERQGHWESATVPGGPSRPWWAMRCLITAQVTAARRGAEQALE
                     VLRDARHDEGLRRRLVLEDPSATAWCVRTALAAGDREFAARIADCAGEVAALARTRPAT
                     GAAAAHGRALLTGDVTLLARAVDGYGDPWAVASATEDLGVLLCGGDREGAIGAFNAAMA
                     GYDGLGAKRDSARVRRRLRRLGVRRRHWNLVARPQTGWDSLTGAEEKVAQLVARGLTNR
                     QVAGELFISPHTVSFHLRQIYRKLAIQSRVDLTRIVCAPGARTAPAPFGAE"
ORIGIN
        1 atgctggaga gcatcgttgt cgtcggtggc ggaacatcgg gctggatgac ggcctcctat
       61 ctgagcgccg cgttcggcga gcggatatcc gtcacggtgg tggaatccgc ccgggtcggg
      121 accatcggag tcggcgaggc gaccttcagc accgtgcggc atttcttcga atacctcggg
      181 ctttccgagg agacatggat gcccgcgtgc aatgccacct acaaactcgg tatccgcttc
      241 gagaactggc gggcaccggg ccaccatttc taccatccct tcgaacggca gcgggtggtg
      301 gacgggttca ccctccccga ctggtggctg gccgacggcg gcgccaccga acggttcgac
      361 aaggagtgct tcctcgtcgg caccctgtgc gacacgatgc gctcgccccg ccacatggac
      421 ggcgccctgt tcgaggggga cctcaccgac cgccccgcgg gccgcagcac actcgccgaa
      481 cagggcaccc agttcccgta cgcgtaccac ttcgacgccg cgctgctcgc cgacttcctg
      541 cgggactacg ccgtcgcgcg cggggtgctg cacgtggtgg acgacgtggt ccacgtcgcc
      601 cgggacgagc gcggctggat cagccatgtc gccacccggg gcagcggtga cctggccggg
      661 gacctcttcg tcgactgcac cggcttccgc gggctgctca tcaacgacgc cctggacgag
      721 ccgttcgagt cgtaccagga caccctcccc aacgacagcg ccgtcgcgct gcgggtaccc
      781 gtcgacatgg aacgcgaggg gctgcgcccc tgcaccacct ccaccgcgca ggccgcgggc
      841 tggatctgga ccatcccgct gttcggcagg gtcggcacgg gctacgtcta cgcccgcgac
      901 tactgcaccc ccgaggaggc cgagcgcacc ctgcgccggt tcgtcggccc cgccgccgac
      961 gatctggagg ccaaccacat ccggatgcgg atcggccgca gccggcgctc ctgggtgaac
     1021 aactgcgtcg ccgtcggact gtcctccgga ttcgtcgaac cactggaatc caccgggatc
     1081 ttcttcatcc agcacgccat cgagcaactg gtgaagcatt tccccgacgc cgactgggac
     1141 cccgccctgc gcagcgcgta caacacgctc gtcaaccgct gcatggacgg tgtccgggaa
     1201 ttcctcgtcc tgcactacta cggtgccgcc cgcgccgaca acgagtactg gcgggacacc
     1261 aagacccgga agatcccgga ctccctcgcc gaacgcgtcg aacagtggcg gacaaaactc
     1321 ccgcacccgg aatccgtgta tccgcactat cacggcttcg aggcctattc ctatgtgtgc
     1381 atggtgctcg ggctcggcgg aatcccgctg aaaccctcac ccgcgctgcg catgctcgac
     1441 ccgtccgccg cgcagcggga gttccggctg ctggccaccc aggccgagga tctgcggcgc
     1501 acactgccca gccagtacgc gtacttcgcg cagttccgct gagcggcggc ggccggagcc
     1561 gtggcgatga cgatcgatct gctgtggtca gtactgcatc tgaccgccct gctcggggcc
     1621 ctcggcctgg tcgcgctgac cgggcgggcc gtcgcgcggt ggctgcggct gccgctggtg
     1681 atcggggaga tactggtcgg cctgtgcgcc gggcccgccc tgctcgccct gctcggggga
     1741 ccgggcttcg accggctgct gccggaccat ctcgccgtcc cgctggcccg ggtcggtgag
     1801 gcggggctgg tgctgttcct cgtcggtgtc gtccacgggc tgcggcacgg cccggccggt
     1861 ccggcgaacc gggccctcgg ccgggtgagc gccggggtgt tcctgctgcc gctgctgacc
     1921 gggctgctgt tcgccggctg ggtgctgtgg ctcggcccgc cgggcctggc cggtacggcg
     1981 ccgctgcccg cgctgctggt gatgctgccc gtggcgatga gcgtgacggc ggtgcccgtc
     2041 ctcgcctgtg tcatcgacga acgcgggccc gggctcggcc gggccgcgcc gctcgccctg
     2101 atgtccgcga tcctgctgga caccgtggcg tggctgctgc tggccgtcgc gctggggctg
     2161 gccgccgggg gactgtgggg ggtggccggg gcgttcgccg cgctcgccgt cgggctgctg
     2221 ctggcgcacg gaggccgccg cgcactcgcc cgcccccgga tcacggcggc cgccgcccgc
     2281 cgccccacgg ccgccgccgt gctgctcggc gggctcgcgc tgctggcggc gaccggggcc
     2341 cacggcgcgg gactcaccgc cgtcctcggc gcgttcctcg cgggcgtcat ggtcccccat
     2401 gaccccgacg gcccctggac ccgggcggtc gccgtcgtcg cccgggtcgg ccgggtgctg
     2461 ctcccggtgt tcttcgtcgg caccgggatc accctgttca ccgaatcggc gggctcgctg
     2521 ccctggtccg cgaccctgct gtgcaccgcg ctggcgatcg tcggcaaggt cggcggcgga
     2581 tacctcggcg cgctgtgggc gggggaggac cgccggaccg cgctgcgggt cggcgtcctg
     2641 gtcaacaccc gcggactcac cgagatcgtg gtcctccagg tgggctgggc ggcgggcatc
     2701 ctcaccccgg gactgttcct cgcgatgctg gtcatggcgc tcgtcaccac cgtcctgacc
     2761 ggaccgctgc tctccctcat cgaccaccac gcggcctccc gggagccgct cgtgcgaaca
     2821 ggcggtgttc cgtgaaactg tccccagaga tcaccccgac ccggttccgc gccctgatgg
     2881 ccgggttccc cagcggtgtc gccgtcctca cggccacgga ccccgacggc gggcgcccgt
     2941 ggggcatgac gtgctcctcc gtgtgcgcgg tgtcgctcgc cccgcccacc ctgctggtct
     3001 gtgtgcgcac cggcagcccc accctggacg cgatgctccg ccggagcgcc ttcgcggtga
     3061 acctgctcca cgacggggcc cgcgccaccg ccgaactgtt cgcgtccggg gcgccccacc
     3121 ggttcgacca ggtccgctgg gagtacccgg tgacgggcgg cggaccgcat ctggtcgagg
     3181 acgcgcacac cgtcgcggac tgcgaggtca gcgggcacca ggtggtcggc agccacgccg
     3241 tggtgttcgg ggaggtgacc gcggtccacc acaggagccc gccgcgaccc ctgctgtacg
     3301 ggctgcgccg gtacgccgcg tggcccctgc ccgacgtgga caccgtctcg tgggtggccc
     3361 cctgacggcc gtctcctgga cggcccctgg acggcctctt ggacgacctg acggcggccc
     3421 gccggcacag ctcggcatgc ctccgcacgc ctcgacggct ccgcacggct agggcacggc
     3481 tccacgcgta cgcccgactc gggcacggcg tccaccgacg gaaggtcgcc caggaacgtc
     3541 acccaggggc gtcgtcgccc gcgtcggtgg ccgcgggcag cagccaggcg agggccgccg
     3601 acaccgcccc cgcgagcgcg tccccgccgg gcgggagctc cacgagacgg tgctcggcgg
     3661 tgagcgcccc ggccgccgac cgtgacgacg ccacggggac ccgtgccgcg cccgtaccgt
     3721 gcacgatcag ggtgggcgcg gtcaccgcgc cgagcacccc gcgcggctgg agccagaaga
     3781 cctcgttgag catcgcccgg cccgccgcca gtccgcaggc agacgcgagc gcgccgtctg
     3841 ccagcagcgt ccggcccgcg ggctcggtca gccggccgcc gcgccaccgc ggcgaatccg
     3901 ccgtgaagtg ctcctggtag tcgatcagcg gatcgaacag caccagccgg ccgatctcgt
     3961 cgccgcgccg cgccgcgtac cccgcggcca ccccgcccgt gagtcccgcc gccagtacgg
     4021 cgatccgggc ggcaccggtc cgctcccgca gctcccgcag cccggagccg atcagattga
     4081 gcagcccgga caggctcagc tccgcctgcc gcccctcgct gtgcccatgg cccggcagat
     4141 cgaagcggag tgtggccacc ccgccgtccg ccagaccccg ggcgacccgg gtgaaaagcc
     4201 cgccctgctc ccggtcggca cccgacccgt gcaggaacag cgccgcgtcc cgggagccgt
     4261 cgtgatgccc cggcggtacc aggagcgtgc ccgcgagccg cagtccgtca tgggtgcgga
     4321 cgaggacctc cgcgccggtg tccggcgggt tcgccggcag ggtcgcatcg gacatcacaa
     4381 cactccgttc gggcgggggc cggagcgcca gcgtgccccc gcccggcgcc cgtgggtggt
     4441 ccggcccccg gattcccccg gctcgcacgg tgtggacgac cgccccgcac gcgaccggcc
     4501 ccgcagggcc accgcaaacc gtcaaaggcc cccggtgagt ggggatgtgg gcgcggtcgc
     4561 cggtccacaa gattaggggc cgggggttcc accgccctga cggtcggtgc tccggacgaa
     4621 gtcccgtcgc ggatggcgga ggccgtcacc tcggccccgg cacccgggac ggcccatcgc
     4681 cctccccggt cccgtcccct ctgccgaagg agtccggtgc gcaggaacgg ctcggcggcc
     4741 acgggcgtca cccgcccgta cccgcccctc tcgaccatcc cccgcccgcc cgcgtccgcc
     4801 gggcatccgc caccggggcc caaacggatc accgtcgtcg gcgccggtat cgccgggctg
     4861 atagccgccc atgaactgga acgcctgggc catcgcgtcc aggtgctgga ggcgggactc
     4921 gcccccggcg gccgggtccg cacccacggg ttcagcggac gcgcccacgg accgctcgtg
     4981 gaactgggcg ccatgcgcat ccccgcctcg caccacctca ccatgcagtg gatcgaccgg
     5041 ctgcggctga gcgaccgcgt acggcagttc cgcaccctct tctccgacga cgccagttat
     5101 ctggcgaccc cggccggaca cgtccgggtc cgggacgcct caccggtcct cgtcgaggag
     5161 ttccgccgga gcctgccgcc gggcccggac caccggcccg agaccctgct gtgcgcggcc
     5221 tggctcgcgg cgagcgtcca cgcggtcgcc cccggcacct tcggacgcgg actgcacacc
     5281 gatctgcccg tcgaactcct cggcctgctc gccggcatcg acgtccggcc ctacctcgtc
     5341 ggcggcgccg cgacccggat cgacctcaac cggttcttcg cccaccacca ggggttcgcc
     5401 gcgcacggcc ggttccgcta cttcttcgac gacgtcgtca ccgagacgtc ctcggcgctg
     5461 ttccggctgg acggcgggat ggaccagata cccagacggc tcgtcgccca gctgcgcgga
     5521 cccgtccgct ggggccgccg ggtggtcggg ctgcacgcac ggcccgacgg ggtcacggtc
     5581 gacacccggc acggactgtc cacggaacgg ttcgactgcc cgtacgtcct gtgcaccctg
     5641 ccgttctccg tactgcgccg gatgccgctg accggggtcg gcgacgacaa gaccgcggtg
     5701 gtcaacgaca tgcagtactg gcccgccacc aagatcgccc tgcactgccg ggaggcgttc
     5761 tgggagaacg acgggatcag cggcggcggc tccttcaccg ggggactcac ccgccagacc
     5821 tactacccgc cggtggagag cgacccccgg ctgggcgccg cgctgctcgc cagctacacc
     5881 atcggccccg acgcggaggc gctcagcgag gtgccgaagg acaagcgcgt cgccaccgtc
     5941 ctcggtgaac tcaagccgat gcaccccgaa ctggcctccc cgggcatgct cctcgacgcc
     6001 cggagccagg tgtggggcga ggacccgctg agcatgggcg ccgcctccgt gcggtggagc
     6061 aaggacccgg acaccgccga ggaggaacga cggctcgccg ccgcgccgca gggcgccctg
     6121 ttcttcgccg gcgagcactg ctcctcgacc cccgcgtgga tcgagggcgc gatcgagtcg
     6181 gggctgaccg cggcccggga gatccacggc catgtcccgc tgaaccgcgg ggtgacggcg
     6241 ccgggacacc gggtgggcgc gggcggcgcg cgatgagccc ggcggacggc cggggcggac
     6301 catccccagg aggatcgatg aacccctcgc acgacaccgg cgtactgatc gtcggcggtg
     6361 gccccaccgg tatggccaca ggtctggaac tgcggtcccg cggcgtcgac ttcaccctcg
     6421 tcgaagcggg tgacggcagc gtcacccacc ccaaggtcag cgcgatcggt ccgcgttcca
     6481 tggagttctt ccgccgctgg ggcatggccg accgggtccg cggcgcgggc tggcccgggg
     6541 accacaccct ggactgcgtc tgggtcaccc gggtcggcgg ccatgagctg taccggctgc
     6601 cgcgccgcac catggacacc cgcgccccgt tccggcacac ccccgaaccc gacgccatct
     6661 gcccccagca ctggctcggc cccctgctcc gcgaggaact gggcgtgcac cccggcggcc
     6721 cggtccggat gcggacccgg atgacgggct tcacccagga cgcggacggc gtcaccgcac
     6781 ggctcaccga cgaggccacg ggccggacca ccaccctgcg ggcccgctat ctgatcgcct
     6841 gcgacggcac ctcctcgcag gtccgcaagg acgccggtat cgaggccccc gcccgccacc
     6901 gcacccgggt ctgccgcaac atcctcttcc gggcgccacg gctgcgcgag gaactgggcg
     6961 aacgcaacgc caacttcttc tatctgctga tgtcctccgc cctgcgcttc ccgctgcgcg
     7021 ccctcgacgg caaggacctg taccggctca ccgtcggcct gctgggccac ccggactcgc
     7081 tggtcgacgc ggagaccctg gtccgccggg ccatcgccca tgacaccccc gtcgaggtgc
     7141 tgtccgacaa ccagtggcat ctggtgcacc gggtcgcgga gaacttccgc gcggaccggg
     7201 tgttcctcgt cggggacgcc gcccacaccc tgtcgccctc cggcggcttc gggatgaaca
     7261 ccgggatctg cggcgccgcc gacctgggct ggaagctcgc tgccgcgttc gacggctggg
     7321 cgggccccgg actcctcgac agctacacca ccgagcggcg gcccgtggcg ctggaaggct
     7381 tggaggaggc caaccggcat ctcgtccggg cctgggcgcg ggagatcccc ggggaactca
     7441 acgacgacac ccccgagggc gaacggcacc gccgctccct gggcgcggac ctcgccgccg
     7501 ggccggtcgc caaggagttc gacgccccgg agatccatct cggcttcagc tacgccgact
     7561 cccccctggt cgtccccgat ccgaccgtcc ccgccgacgc gcacgacgac cggcggccca
     7621 actcccggcc cggctcccgc gccccgcacg cctgggtgaa gcccgggacg tcgaccctgg
     7681 acctgttcgg cgacgggttc gtgctgatgt ccagcacccg ctcggcccgc accgacggct
     7741 tcacccgcgc cttcgccgac cggcgcgtcc cgctgaccgt cgtccactgc gaggtccccg
     7801 aggtcgtcga gagcctggag cggcccttcg tcctcgtccg ccccgacgga catgtggcgt
     7861 ggcgcggcca tgaactgccc gacgaccccg ccgccgtcgc cgcccgggtc accggcgcgg
     7921 gtacggggac cggtacgggt acccgcgcag gtaccggcac ggactccggt acgggcgcca
     7981 gcggcaccgg gggagcgcca tgacccccgc cacggccccc gccgccctgc ccccgttcgg
     8041 cctcaccggc tggcccgccg aacgcctcgc cgacccctac ccggtctacc gccgctaccg
     8101 cgccgccgcc cgcgtccacc gggccgaacc ggacggtacg gcaccgacgt tctacgtact
     8161 cggccacgac gaggtcgcca aggtcctcag cgcccccgtc tacggccgca gcccccgccg
     8221 cgccaccggc ggcgccccac ccgcgacggt cccgaacggc cactccgcgc tgcggagcat
     8281 ggtcgagaac tggctggtct tcctcgaccc gccccgccac accgaactgc ggtccctgct
     8341 gaaccgggag ttcacccccg gtgtcgtcac cgatctgcgc ggccggatcc aggacatcgc
     8401 cgtcggcctc ctcgccgaac tcaccgccga ggccgcccgc accgggaccg tggacctcgt
     8461 cgaacggttc agcgcgccct tcccgatcct ggtgatctcc gaactgctcg gggtggaccg
     8521 gaccgactgg gcctggctgc gcgaacaagc cgtcggggtg cagcaggcga gcagcagccg
     8581 cgccgcgctg cgccccgacg cgcaccacgt cgccgagacc gccgcccgcg aactcacctc
     8641 ttacttcctg gaactggccg cccggcgccg cgccgaaccc gccgccgacc tggtgtcgct
     8701 gctcgtgtcg gcgcagaccc ggggcgaacc gctgaccgac gcggagatcg tcgcgacctg
     8761 cgtgcatctg atgacggcgg gccacgagac caccaccaac gtcctcagca agtccgtcct
     8821 caccctcacc gcgcggcccg cgcagctcgc ccggctgcgg gcggcgccgc tcgtcccggc
     8881 gcccgcggtg gaggaactcg tccgcttcga cccgccggtg caggccgtga cccgctgggc
     8941 ctaccgcgat gtggtgctcg gcgggcacca cgtaccccgc ggcagcaagc tcttcgccgt
     9001 gctcggggcc gccaaccgcg acccggcgcg cttccccgac ccggacaccc tcgacctgga
     9061 ccgcggcgga cgcaacctcg ccttcgggct cggcgtccac tactgcctcg gcgccggcct
     9121 cgcccgcacc gagatcgaga tcggactggg actgctgctg cgcgccctgg ccgccctcgg
     9181 cgacagtgag gtcgacgagg tccactaccc gtacgacctc gtgttccacg ggcccgagcg
     9241 gctcaccctg cggctgcgct gacctccggc gaggtcgccc gcagcagcac ccggtcgagg
     9301 aaggcgacca gcgcgccgac ggcgtccggg gccgggaggt ccaccacggc cccgagatgc
     9361 ccgtccggcc ggaccaccac cagccgcgcc cccttcacct ggtacgcgcg gtacgccgcc
     9421 gtctcctgcg gcggcaccgc gtggaccgtc accatccccg ggtagcggtc gtccagcagc
     9481 tccgcgagct cctggacgtc cagccccgcc gcgccggggt ccgccgcgaa ccccaggacg
     9541 tgatagccgc tgccatgggt caggtccagc acactgcccg tcccgtcacc ggcccgcgcc
     9601 agcagcgcgt acggggcccg gtcgccgggc cgcagcccgc ccgtcaccgg ccgggcggcg
     9661 gcgaccgcgc gtgaaccccg gtagccgatc cacagctgcg agaacatatg gaagaacatc
     9721 cgccgcaccg gcgcgagacg gctgaccacg ccgaccaccc gggccgccac ctgggtccgc
     9781 atccacaccg cgaccgcccc gtcgccggtc tccgcgcgga accccagatc ggtgcgcttg
     9841 aggacggtcc gcgcgatggg ccgccgctcc gactcgtagg tgtccagcaa ccacggcggc
     9901 gcctggccgt gcaccacctg cgccagcttc cacgccagat tgaccgcgtc gcccaccccc
     9961 aggttcagcc cctgcccgcc cgccgggttg tggatatggg cggcgtcccc gatcaggaag
    10021 caggagccca cccggaaccg cggcgcgatc cggctgtgga aacggaacat cgacgcccac
    10081 acgatctcct ggagccgcgc gtccacccgg aagtagtcgg cgaaccagcg gtgcagcacc
    10141 tccggttcca gcgccgcgta cgcctcgtgg gaggtctcga cgggctcctg ggccttgtgc
    10201 accgacggcg gcaccacccc gaacagccgg caacgcccgc tcgccagcgg caggatgccg
    10261 acgaaaccgc cccgggtcag gttcagccgc atcccccgca ccccgagatc ggcgtccagc
    10321 acgacatccg cgagcatccc gctctgcgga tacgtccgcc ccccgaactc cagccccagc
    10381 gactgccgga cggtgctgct cgcgccgtcc gcgccgatca gccagcgcgc cgtcaccgtc
    10441 tcctcgccgt ccgtgcgccg caccgtgaca cgtaccccct caccggtgtc ggccagcgag
    10501 tcgagcgcgc tgtcccactc gacgtccacc gcgtgctcgg ccagcgcctc caccagcaac
    10561 cgctgggtct cgaactgctc cagcgccagc gcgtacggga accgggtcca ggccgcggtg
    10621 cccgcgcccg cgagcggcat ccgccccgcg tgccggcccc gctcatggat ggccacctgg
    10681 gtgatcggca gcccccgcgc caccgcctgc gccgcgaccc cgagccggtc cagcagctcc
    10741 agcgtgcggg cgtgcacgat cgccgcccgc gcctcctcca cgggccccgc ggcgcggtcc
    10801 acgaccctga cccggacccc ttgctgcgcc agcgccagcg cggcggtcag tccgctcgga
    10861 cccgccccga cgacgaggac gtcacaatcg tgtgcgtcac gcataggacc tcacagcgtg
    10921 gaagtcggtc ccggagccgg tcccgggacc cccggccccg agtgtccccg gcgcgcgcgg
    10981 ccgtccgcat cgcgcgtcgc acgacccggc ggacggttct cggcggacgg cggccccgcc
    11041 cgccgcccgc cggaggtgac cccgggcccc cgcgcggccc ggcaccctac gcgagtgcgc
    11101 ggtatccggc gcaccgccgc cgccaccgct tccggccgcc gggaccggac tataggttct
    11161 ggcctgcccg tggcgggcgc cgaggcccgc cccgacccgc cgaggacgtg cagatgaccg
    11221 accaggcccc cgtcccgccc ccaccacagc cgtacttcga cgacctcgcg gacctgtacg
    11281 agcggttcac cagcatccgg gacggcgcca ccagcccggt ccgctcctgg ctcgtcggcc
    11341 agctgcccaa ggggcaacgg gccctcgaca taggctgcgg cggcggcaac aactgcgtga
    11401 tgctcgcgga acgctacgac gaggtggtcg gcgtcgacat ctcccgccgg atgctcgaca
    11461 tcgccgccgc caaaccggcc cgggtcccgg tgcgttacca gcaccgcagc gcgctggacc
    11521 tcacccccgc cgccgacggc accttcgacc tggtgatgtc cgtcaacgcc gtcttccatc
    11581 tgggccccgc cccccgggtg ctgccccggc tgcgcgacct cgtcgccccg ggcggccggc
    11641 tcgtcgtcat cgacgtcacc cggcccgacg cgaccggcac ggacaccgac gccgcgccgc
    11701 ccgccgaacg cgacacgtac gccttcgaca ccgcgcgcac catctacgag gtctccggcg
    11761 acgcggacgc cgccgccgac tcgctgcgga tgatgctcca cccgcgctgg ctggagatga
    11821 gcgccgccca tatgccgctc acctacggcg agttcgtccg cgcctaccgc gaacagctgc
    11881 ccggagtgcg aatcacccgc gacctcatcc ccaccatgag cgccgccgtc tgggacgccc
    11941 cgtgagcgtg ctcgacgtgc cccgggtgca cttcgccggg gccgccgtca cccggctgcc
    12001 caccggcccc cgctccggac tgtacgacct cgccaccggg cgggccctca ccgacgacgg
    12061 ccctttcccg ctggaacgcc ccgcccgcga gtaccacgac ctgctgcgcg cccgcggcga
    12121 gcgctacgaa cccgacggca ccctcacccc cgacggccgc ttctccacca ccaccggctg
    12181 gaacttcggc ggcaacggcc acttctggat cgacgcccgg gtcaccggct gcgaacacac
    12241 ccccggccgc gccgcgaccg acgacccgct ggtgggccgc gccgtcgacc tgtggggcca
    12301 cttctgcgac tacaccgcgg gcaccgtcaa ccgctgccgt gtcctcgatg tcgaccccgc
    12361 gtccccgtgg accaccaccg tcatgatcgg ccagctcgcc ctcggccgcc tcggccgctc
    12421 ccacgacgtg ggctatctgc tcaccggcga cgtcaccggt atgagcccgc cgcgctggcc
    12481 caacgcccgc tacatcgacg acgtcggccc gcaccccctc gccgaccggt tccgccgctc
    12541 cgtcgtccac cagttcgccg tcgaacgcgg caccggactg cactggctgg acggctccgc
    12601 cgactcaccg gccctcaccg cgctgcggga cctcctggac tccggcgccg ccgacggact
    12661 cgtcgtccag ctcgccctgt ccaacatgtc cacccccacc gacaacgacc agcccgactt
    12721 ctgggacctg cgcggtgtcc tcgccccctg gcacgcccac gaactgcgca cctaccccgc
    12781 cggacggctc ctcaccggcc gccgcgtacg ggccgccggt caccacgcac ccctgcacaa
    12841 cctcaccgtc cgcgtggacg acgagcacgt caccgcgaac ctcgtcaccg cgctgcccgt
    12901 caccggccgc gccccgctgc gcggccccgg ccccacccac cgcaccggac ccctcgccga
    12961 cctcggcgac ctccagctgc gcgccgccga cggcaccctc gtcgccgtcg tccgcggcgc
    13021 cgactacctc ggcgccggct accggcgcac cggcggactg ctcaccctcg accggatcga
    13081 cggccgcacc ggcgaacccg ccggcccgct gcggatcacc tcgccggacg gcaccgtact
    13141 ggccgacgag gaggagaccg tcgtccagtc cgacgaggcg gcgctgttcc tcgaacaccc
    13201 caacccccgc accggcgaag acttcgcggt ccaggtgccc gtccgctcct acgtccgggg
    13261 ccgccccgca cgggccacgg gcatccgggt ccagcagtac cccaaccccc gcgcgctgcc
    13321 cctcgacccg gccgcgcagt cgcccgacgc ccgccccgcg gacatccccg tcaccgcgtt
    13381 cctggccccc ggccgcgccg actacaccgc cgacagcctg ctgtccaccg acgaacacgg
    13441 ccacggcacc ctcaccctgc ggggcgccgc ggcgggcgcc gccctggtcc tgctgctccc
    13501 cgccggtgaa cagccccccg ccgaccccgc cgagccgggc tcagccgccc gcggctacga
    13561 ccacgacgac gacctcggct actggcccgc cgccggcagc atcgccgtcc gggtgctgcc
    13621 cgaccactgg cacctcgacg acctgcccga cagcgccatc accttcccgc tggtctaccg
    13681 ccaggccctc gccccctacg aactcctcta ctccttcatg agcgacgagg tgctcagcct
    13741 cgccgacgag ttcaaggtcg agacatacgc ccggctgatc tggcacgtca gcgcccccga
    13801 acaccgggac cggacgttct acatgccctc cacccgcgat ctgagcgccc ctcagatccg
    13861 gctgctgctg cggtacatgc tcgccgacga ggcgaaacgg cagaccccgc ccgtcctcgt
    13921 ccccccgcac cggacccccg gcacgatcac cacccgcgac gccctgctgc gggccctgcg
    13981 ccaggccgcg gccatcgaac tcgccaccat gatccagtac ctgtacgcgg cgtactcggt
    14041 ccccacccac ggcgccgccc gccactacgt cgagcgcggc gaatggaccc ccgcccagct
    14101 tctcctcgcc tgcggcgaag gcccgcagac cctcagcaac ggcatccgcg gcagcctcac
    14161 caacgtcgcc cgcgaggaga tgatgcactt cctcgccatc aacaacatcc tcatggccat
    14221 gggcgccccc ttccaggtgc ccgacatcga cttcgggacg ttcaaccacc gcatcgacgt
    14281 ccccctggag ttctccctcg aacccctcgg cctcggcagc gtccagcggt tcatcgccct
    14341 cgaacagccc cacaccctca cccaggagat cgcgggcaac gactccacgg ccgacggcgg
    14401 gaccgcctac cgctacggat cgctcagcga gctgtacgcc gcgatccgcg acggcatcca
    14461 gcgcgtcccc ggcgcgttcc tcgtccgcaa gggccgcggc ggcggggaac accatctgtt
    14521 catgcgggag tccgtcaacg ccgtgcaccc cgactaccag ctcgaagtgg acgacgtcac
    14581 cagcgccgtc ttcgccatcg acttcgtcac cgaacacggc gaaggcggct ccatcccctc
    14641 cgtcctgccc gacgaggact cccacttcga caccttcctg cggatctccg acgccctcgt
    14701 ccacgaacgc gcgcagggac cgaacggccg cgccgtgccc tggaaccccg cctaccccgt
    14761 gctccgcaac cccaccctgg acctgcggag caccgccaag gaccccgtca cccacgaacc
    14821 cgcgcgccgc gccatgaccg tcttcaaccg ctcctacgcc ctggccatgc acctgatggt
    14881 ccagcacttc ggccacagcc ccgacaagag cctgcgccgc tcccggctca tgaactgggc
    14941 actggacatc atgaccggcg tactgcgccc ggtcgccgaa ctcgtcgtca ccctgccctc
    15001 cggacgcccc ggccgcaccg ccggaccctc cttcgaactc ggcaccgtcc cccagtacat
    15061 cgcccggccc gatgtggccg ccgcctggct ggcccgcgag ttcgacgaga ccgcctccct
    15121 cgcccggggc tgccccgcac tcacccccgc cgtggccgac ctcctcgcct tcatcggcga
    15181 ccggctgcgc accatggacc cccgggagat gtgatgagcg gcccggctcc cacccgcacc
    15241 accgtctgcg tggtcggcgg cggccccgcg ggcgcgatgc tcggcctgct gctggcccgc
    15301 tccggcgtgg acgtcgtcgt cctggagaag caccacgact tccaccgcga cttccgcggc
    15361 gacaccgtcc accccgccac cctgcgcgtt ctcgaccagc tcggcctcat cgaccgcttc
    15421 cacgcgctcc cgcaccagaa ggtcaccacc atcggggtga tccaggacgg ccaccgcatc
    15481 gacatcgcgg acttcagccg gctacgggtc ccctacccct acatggcctt cgtcccccaa
    15541 tgggacttcc tcgacctgat caccgccgag agcgcccgcc accccgcgta ccggctgctg
    15601 atgggcaccg cggccaccgg ggtgctgcgc gacaccgacg gccgcgtcag cggcgtacgg
    15661 acccggggcc ccgacggcgc cgccgacctc cgctgcgccc tggtggtcgc cgccgacggc
    15721 cgccactcgg cgctgcgggc cgcggtgggc gcccggccga aactcatcgg ctcctccctc
    15781 gacgtgggct tcttccggat ctcccgccgg ccgaccgacc ccgacgaggg catctgcgtc
    15841 cgggtcggca acggcaagat cttcggcgcg accgaccgcg gcacctactg gcagatgtcc
    15901 tacgagacca cccgcggcgg cttcgaccgg gtcaggcacg cgggactcga cgcgttccgc
    15961 gccgacctcg ccgcactggt gcccttcctc gccgaccggg tccacgaact gcgctccctg
    16021 gacgacatca gcctgctgga ggcccggatc gaccggctcg cccgctggca ccggcccgga
    16081 ctgctgttca tcggggacgc cgcacacgcc atgtcccccg tcgccgggtt cggcgtcaac
    16141 ctcgccgtcc aggacgccgt cgccaccgcc aacgccctct gcgcgcccct gctgcgcgcc
    16201 cagcgcaccg gcgccgcctt cgacgacagc ctcctcacca aggtccgccg gcgcagactg
    16261 gtcgccaccg ccctctccca gggactgcaa cgcgccaccc agcgcttcgg catcgacacc
    16321 accctcaacg gctcaggaca gccgcccgcg ccccggctgt tcgaacgatt ccggcccgca
    16381 cagctcctga tgagcagggt catcggggtc ggcttccgcc ccgaacacat ccgcacaccc
    16441 ccggcccgcc ccgccgacca cgagaaggac ccgacatgag cgcagccgac cccgggggga
    16501 ccgggcccgc cccggccgac cggatgatgt cgatgatcac cggctactgg gtgacccaga
    16561 tcgtccggac cgtcgccgag ctgtcgatcc ccgaccagct cgccgagggc ccgctgacgg
    16621 ccgccgaact cgccgcgcgg atcgacgccg accccgacgc ggtcgcccgg ctgctgcggg
    16681 cgtgcgcgtc gctggggctc accgaggcgg acgaccggcg cgcgttccac cgcacacccc
    16741 tgctcgacac cctgcgcgcc gggaccccgc actccctgcg gacgatcgcg ctggtccacg
    16801 gctcacccgg ccactggctg ccctggggcc tgctccccga cgccgtacgg tcggggaccc
    16861 cgcagaccgg ggccgccctc ggccgggaca tctgggccca cttcctcgcc caccccgagg
    16921 agggcgaacg cttcgcgacc tccatgaccg aactgaccgc cgggctcgcc gaggaggtcg
    16981 ccgccctgat cgacacggac ggcgtcgggg tcgccgtgga tgtggggggc gcgaacggcg
    17041 cgctggtgca cgcgctgctg cgcggcgacc cacgaccgcg cggggtggtc gtggacctgc
    17101 ccgccgtcga ggaatccgcc cgcgccgaag cgcgcgaggc gggactcgcc gaccgggtca
    17161 ccgtggtcgg cggttccttc ttcgacccgc tgccccgggg cgacctcttc ctgctcaagg
    17221 cggtcctgca caactgggac gacgacgcct gcacggccat cctgcgcaac tgccgcgccg
    17281 cgctgaaccc ggggggccgg gtgatcgtgg tggagatgcc cctgggcccg ctcggcgagc
    17341 ccggcttcgc ccccctcctg gacctcaaca tgctcgcggt cctcccgggc cgcgaacgcg
    17401 acctcccgca ctacgacgcc ctcttcgcgg ccgccggcct gcgccgcacg gggatcaccc
    17461 ccacccgttc cccccagcgg ctcatcaccg cggtaacggc cgggagctga cccccggccg
    17521 ctaccggacc gtgtcccctg ggaaggccag gaccccgcgc ccggtgcggg ggaccaggac
    17581 cggaccgggg ccgccgggaa ggcgaagacg gcgcgcccgg tgaagacggc ccgcacggga
    17641 acgggtccgc gggggagccc aggaccccgc acccggtgcg ggcgacccgc aacggaccgg
    17701 gtccccgggg cggcgaccac cccgggcccg gtgcaggcga cccgcacggg aacgcacgac
    17761 ggcccccccg aaggccccgc cagggaacgc ggctcggccc ctggcgggct cccggggcgc
    17821 acggcggggg cctactcggc cccgaacggc gccggcgccg ttctcgcccc cggcgcacac
    17881 acgatccggg tcagatccac ccgcgactgg atcgccagct tccggtagat ctgccgcaga
    17941 tggaaactca ccgtgtgcgg cgagatgaac agctcaccgg ccacctgccg gttcgtcagc
    18001 ccccgggcga cgagctgcgc caccttctcc tccgccccgg tgagactgtc ccagccggtc
    18061 tgcggccggg cgaccagatt ccagtgccgc cgccgcaccc cgagccgccg cagccgccgc
    18121 cgcacccgcg ccgagtcgcg tttggcgccc agcccgtcgt acccggccat ggccgcgttg
    18181 aacgcgccga tcgccccctc ccggtcgccc ccgcacagca gcacgcccag atcctcggtg
    18241 gccgaggcga cggcccaggg gtccccgtac ccgtcgacgg ccctggccag cagggtcaca
    18301 tcgccggtca gcagggcccg cccatgcgcc gccgccgcac ccgtcgcggg ccgcgtccgg
    18361 gccagcgccg ccacctcccc ggcgcagtcc gcgatccgcg ccgcgaactc ccggtccccg
    18421 gcggccagcg cggtacggac gcaccacgcc gtcgccgacg ggtcctccag caccagccgt
    18481 cgccgcagcc cttcgtcgtg acgggcgtcc cgcagtacct ccagcgcttg ttcggccccc
    18541 ctccgcgcgg ccgtcacctg cgctgtgatc aggcaccgca tggcccacca cgggcgcgac
    18601 ggcccgccgg gcacggtggc ggactcccag tggccctgcc gttccagggc ctcggccaga
    18661 tcaccccggc gcagcgccac ggccaccagc acggcccgca gatgcggttc gcacagcggc
    18721 atccgggccg cgtcggacgc ggtgatcccg gcccgcgcga gctgctcggc ctcggccagg
    18781 tcgccccggg cgaagctcac ccaggaccgc aacgcgaact gcaacgggtc cagtaccccg
    18841 ttggagtcgg cgtcgatggt gcgccggacc gcttcgacca tgaccgcggc cccgtcgagg
    18901 tcgcggagct tgatcaggat ccacgccgtg ttccacaggg agttgttctg ccagatgccg
    18961 gtgccgtcgt caccgtgcgc gggggtgcgc tccagcaggc ccagcgactc gtcgatccgt
    19021 ccgtcgcccc acagggacat cgcccggatg ttgcgggccg ccgtacacac gtcgcgttcg
    19081 tgggcggact cgtccttcag tacctcgtcg gccgccgcca gcgcggcccg ttcgtcggtg
    19141 tgggacagca tggtgagccg cagcagcagc ggcgacgggc tgccctggcc ggggcccgcc
    19201 ccgtccgcgg ccgggtccgg gggcccgccc gccgcggcgt cgcacaggat ccccggtacg
    19261 gaggcggcct ccccgcgcag cagcagcgcg gtcgcgagcc aggcccgcag cggccaggtc
    19321 cgggcgtcct ggcgggcgcc gtcgccgggc cgcgccggat gcgcgcgccg gtgtccggcg
    19381 accacgcgtt cggcgacgtc caccgcccgg tgcagactgc ccgagcggac gagcgcggcg
    19441 gtcgccgtgg tggccagcgc gatgtgctcg ggctgggtcg gcgtggtgat ctccagaccg
    19501 cgcagcgcga gcgcggcggc ggcctgcggg gacaccggga gcagccggtc cgccgcctcc
    19561 cggatggtgg tgatggcctg gtcgtcgtcg gactgggcgc agtgcaccag atgcaccgcc
    19621 gcggcggtgc cgtcccccag ctgaccgagg atcatgttcg ccgcctgccg gtgcagcagg
    19681 gaccgcatca gcggtggaac ggtgcccagc accgcgtacc agatcggttc gcggtggaag
    19741 gagaactcct cggtgccgct ggtgaggagt cccgctgcca gtgactcctg gagcgggccg
    19801 aggagttgca cgggtcgctc gtcggccatc tccgccaggt cgcgcggcat gaaggacgga
    19861 ccgaggacgg ccgcgacctg gaggagccgc tgggtgccgg gcgcgagccg gtcgagccgg
    19921 tcgtgcatca gccgcaggaa cgcgcgcggc agatgcgccc cggggtcggg ggcgacggcg
    19981 gaggtgaagc cggaggcgag cggttccgcg acgagcgaca cggtgccccc ggtgatccgc
    20041 aggcactgct cgtccagcag accgcgcacc agctccacga tcgcctgcgg gctgccgccc
    20101 aggctctcgc cgagggcccg tacgtcgtcg ctgggacggg cgcccaggag gtcgcccatc
    20161 agttcggtga ccgcccggtc gtcgagcgcg tcgagctgcg ggagccattc cgcccggtgg
    20221 atggtcaggt tgcgcagcag gaggctgttc gcggaccgcg cgtcctccgt acgcatcgtg
    20281 agcagccacc gcacgggagc ggccagcagt ttgagcgcca gtccgcacag ggtccgcagc
    20341 tgcaccgggt cggcccactg cgcgtcgtcc acgagcacga gcaccgggcc gcgccgcagc
    20401 cccgcgtcga tctgggcctg gacctgcacg gggcccgccg gacgtaccgg gcgcggcacc
    20461 cgcggggcga cggcccggcc cgcgccgacg gcgggcgaag ccgcctcctc gccgcgccag
    20521 gcgcccccgg cggagcagtc gatcacggtg aagccgagtc cctcggcgag ggcgcccgtc
    20581 tcctggagga gccgtgtcct gccgcttccc gcgggggatt ccaggagggt gatgccgcct
    20641 tggcggctct cggcggtcgc ccgcaacgag gcgcgtatct gctccagatg gccgtcgcgg
    20701 ccacggagcg gacggcccac ggccggcggg aactggggga ctgggtcgtc aggcttttcc
    20761 agggtcttcc cgttcat
//
