BGC0001334: caldoniamide A biosynthetic gene cluster from Streptomyces uncialis
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Location: 9,571 - 30,347 nt. (total: 20,777 nt).
This entry is originally from NCBI GenBank JN165773.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001334
Short description caldoniamide A biosynthetic gene cluster from Streptomyces uncialis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
JN165773.1
9571 - 30347
via Enzymatic assays, Gene expression correlated with compound production
Compounds
  • caldoniamide A
  • cladoniamide B
  • cladoniamide C7
  • cladoniamide D
  • cladoniamide E
  • cladoniamide F
  • cladoniamide G
Species Streptomyces uncialis [taxonomy]
References
Chemical products information
caldoniamide A Evidence:
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C22H16Cl1N3O5
Chemical database entries
NPAtlas
cladoniamide B Evidence:
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C22H15Cl2N3O5
Chemical database entries
NPAtlas
PubCHEM
cladoniamide C7 Evidence:
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C22H17N3O5
Chemical database entries
NPAtlas
cladoniamide D Evidence:
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C21H16Cl1N3O4
Chemical database entries
NPAtlas
PubCHEM
cladoniamide E Evidence:
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C21H15Cl2N3O4
Chemical database entries
NPAtlas
PubCHEM
cladoniamide F Evidence:
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C21H16Cl1N3O4
Chemical database entries
NPAtlas
PubCHEM
cladoniamide G Evidence:
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C21H15Cl2N3O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEO12707.1
  • claH
 9571 - 11112 (+) halogenase
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    • AEO12708.1
    • claT
    		 11137 - 12405 (+) antiporter
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      • AEO12709.1
      • claF
      		 12402 - 12935 (+) flavin reductase
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        • AEO12710.1
        • claY
        		 13109 - 13945 (-) putative alpha/beta hydrolase
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          • AEO12711.1
          • claO
          		 14287 - 15846 (+) amino acid oxidase
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            • AEO12712.1
            • claC
            		 15888 - 17573 (+) flavin monooxygenase
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              • AEO12713.1
              • claP
              		 17570 - 18832 (+) cytochrome P450
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                • AEO12714.1
                • claX1
                		 18813 - 20474 (-) flavin monooxygenase
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                  • AEO12715.1
                  • claM1
                  		 20784 - 21515 (+) methyltransferase
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                    • AEO12716.1
                    • claD
                    		 21512 - 24784 (+) chromopyrrolic acid synthase
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                      • AEO12717.1
                      • claX2
                      		 24784 - 26049 (+) flavin monooxygenase
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                        • AEO12718.1
                        • claM3
                        		 26046 - 27080 (+) methyltransferase
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                          • AEO12719.1
                          • claR
                          		 27402 - 30347 (-) transcriptional regulator
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                            Biosynthesis information
                            Annotation changelog

                            Entry version: 4

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-10-07
                            Update chemical activity to schema version 2.11
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 3

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-09-15
                            Updated bioactivity data
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 2

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2019-10-16
                            Migrated from v1.4
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            2019-10-16
                            Updated compound(s) information (NPAtlas curation)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2016-09-03
                            Submitted
                            • (ID: TFC7LOLNUCTKZCZQ4X3ELKJ7)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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