Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001336.1:
Cluster 1Alkaloid112620

BGC0001336, erdasporine A / erdasporine B / erdasporine C biosynthetic gene cluster from uncultured bacterium. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: erdasporine A
SMILES string: Copy to clipboard
Molecular formula: C22H15N3O3
Exact molecular mass: 368.1035 Da ([M-H]-)
Molecular activity: Cytotoxic

Class-specific details

Biosynthetic class(es):
Alkaloid
Alkaloid subclass:
Indole/benzopyrrole

Gene cluster description

erdasporine A / erdasporine B / erdasporine C (BGC0001336). Gene Cluster 1. Biosynthetic class = Alkaloid. GenBank KF551865, positions 2596-15215. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Heterologous expression, Gene expression correlated with compound production
MIxS-compliance:Unknown
Contact for this cluster:Fang-Yuan Chang (MIT)

Literature references

1. Chang FY et al. (2013) Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment. J Am Chem Soc 135(47):17906-12. doi: 10.1021/ja408683p. Epub 2013