BGC0001337 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001337 (uncultured bacterium)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	indole	1	25,750	High	lazarimide A/lazarimide B/lazarimide C	other:other

BGC0001337 - Region 1 - indole

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Location: 1 - 25,750 nt. (total: 25,750 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 25,751
Label		BGC0001337

Tailoring functions

Oxidoreductases: Oxidation oxidoreductase oxygenase

lzrC: Oxidation

MITE: MITE0000070Oxidation (identity: 61.20%)
smcogs: SMCOG1050: monooxygenase FAD-binding

lzrD: Oxidation

MITE: MITE0000067Oxidation (identity: 73.10%)

lzrF: flavin reductase domain protein FMN-binding

smcogs: SMCOG1160: flavin reductase domain protein FMN-binding

lzrG: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

lzrO: Oxidation

MITE: MITE0000068Oxidation (identity: 70.40%)

lzrP: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

lzrX1b: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

lzrX2: monooxygenase FAD-binding

smcogs: SMCOG1050: monooxygenase FAD-binding

Transferases: halogenase methyltransferase

lzrH1: flavin-dependent trp 5 halogenase

halogenases: flavin-dependent trp 5 halogenase
MITE: MITE0000030Halogenation (identity: 65.10%)
smcogs: SMCOG1119: halogenase

lzrH2: flavin-dependent trp 6 7 halogenase

halogenases: flavin-dependent trp 6 7 halogenase
MITE: MITE0000130Halogenation (identity: 68.40%)
smcogs: SMCOG1119: halogenase

lzrM1: methyltransferase

smcogs: SMCOG1089: methyltransferase

lzrM3: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001337.5	0.92	other (other)	lazarimide A, lazarimide B, lazarimide C	uncultured bacterium
BGC0001224.5	0.62	other (other)	reductasporine	uncultured bacterium
BGC0000817.4	0.61	other (other)	methylarcyriarubin	uncultured bacterium
BGC0001336.5	0.60	other (other)	erdasporine A, erdasporine B, erdasporine C	uncultured bacterium
BGC0001223.5	0.57	other (other)	hydroxysporine	uncultured bacterium
BGC0002084.4	0.56	ribosomal	biarylitide YYH	Planomonospora sp. ID82291
BGC0002099.3	0.56	ribosomal	biarylitide YFH	Planomonospora sp. ID107089
BGC0000924.5	0.53	other (other)	pyrrolnitrin	Pseudomonas chlororaphis
BGC0000830.5	0.49	other (aminocoumarin)	violacein	uncultured bacterium
BGC0000813.3	0.49	other (other)	K-252a	Nonomuraea longicatena

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001337.5	1.00	other (other)	lazarimide A, lazarimide B, lazarimide C	uncultured bacterium
BGC0000817.4	0.61	other (other)	methylarcyriarubin	uncultured bacterium
BGC0001223.5	0.59	other (other)	hydroxysporine	uncultured bacterium
BGC0001224.5	0.56	other (other)	reductasporine	uncultured bacterium
BGC0002084.4	0.56	ribosomal	biarylitide YYH	Planomonospora sp. ID82291
BGC0002099.3	0.56	ribosomal	biarylitide YFH	Planomonospora sp. ID107089
BGC0001336.5	0.55	other (other)	erdasporine A, erdasporine B, erdasporine C	uncultured bacterium
BGC0000924.5	0.53	other (other)	pyrrolnitrin	Pseudomonas chlororaphis
BGC0000830.5	0.51	other (aminocoumarin)	violacein	uncultured bacterium
BGC0000831.3	0.49	other (other)	violacein	Duganella sp. B2

Similar known clusters from MIBiG 4.0