LOCUS       BGC0001337             22533 bp    DNA     linear   ENV 19-JUL-2015
DEFINITION  Uncultured bacterium clone AZ25-292/153 hypothetical protein,
            two-component response regulator, and beta-lactamase genes, complete
            cds; lzr gene cluster, complete sequence; and hypothetical protein,
            membrane protein, and peptidase genes, complete cds.
ACCESSION   BGC0001337
VERSION     BGC0001337
KEYWORDS    .
SOURCE      uncultured bacterium
  ORGANISM  uncultured bacterium
            Bacteria; environmental samples.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 00:46:57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3106
            Orig. end    :: 25639
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..396)
                     /gene="lzrX1a"
     CDS             complement(1..396)
                     /codon_start=1
                     /gene="lzrX1a"
                     /product="monooxygenase"
                     /protein_id="AKQ20686.1"
                     /transl_table=11
                     /translation="MFSQLWIGYRGSRAVGRGVGQLKPGARAPYAPLGTGSVLDLTHGT
                     GYHVLLFSVPQPEVVAARFDGRYAAAVTTHVISPSEEAAHRAYKVDGPRLVLVRPDGHV
                     AAVADPGSVDTLIEFLDSVLTRVQAIR"
     misc_feature    1..22533
                     /note="lzr gene cluster"
     subregion       1..22533
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Alkaloid"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22533
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(330..1580)
                     /gene="lzrX1b"
     CDS             complement(330..1580)
                     /codon_start=1
                     /gene="lzrX1b"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 323.4; E-value:
                     4.8e-98)"
                     /gene_kind="biosynthetic-additional"
                     /product="monooxygenase"
                     /protein_id="AKQ20687.1"
                     /transl_table=11
                     /translation="MRDEHDCDVLVVGAGPTGLCTALMLAQHGVRVRIADRRPGPVEQT
                     RATIVHARTLELLDRLGVAETAVARGLPITEVEIHSSGRHAGEMSLAGEGTADQTRFPY
                     ALALEQFEMERLLVNALGEHAVAVEWGTEVTGVADTGSGVSVQTAGDVISARWLVGADG
                     ASSSVRKFLGQEFDGETYDQAGLLADVTLDVSLGVKGMRLNLTRGGFVGILPLRSGRYR
                     LFGVVPPELHNSPRPAAVSHESYAPLDHADLQLWFDDYFKVDARLEEILWASMFRVHSR
                     LAAKFRVGNAFLVGDAAHIHNPAGGQGLNLGVGDAINLAWKLAQVVHGEAPRWLLDTYE
                     AERRPIARTVLRRTDSGSNWRPGTTRWPCGCARTSRLGSSVRSHGLRRCGGCSSTCSPS
                     CGSGTGAAARSVGASAS"
     gene            1718..2410
                     /gene="lzrM1"
     CDS             1718..2410
                     /NRPS_PKS="Domain: oMT (37-140). E-value: 3.5e-10. Score:
                     30.3. Matches aSDomain: nrpspksdomains_lzrM1_oMT.1"
                     /codon_start=1
                     /gene="lzrM1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 92.5; E-value: 5e-28)"
                     /gene_kind="biosynthetic-additional"
                     /product="N-methyltransferase"
                     /protein_id="AKQ20688.1"
                     /transl_table=11
                     /translation="MSAPEAYFDDLAELYERFTGIRDAATSPVRSWLIEQLPAGRRAID
                     VGCGGGNNCGLLADRYDEVVGLDISQKMLDIAAAKPTRVPVRYVCREALSLSPERDGRF
                     DLVMSVNAVFHMGPVDQVLPVLRDLVAPGGRLVIVDVTLPDGAAASAEQSAYAFETGKI
                     IYDVSGDVEAACDSIRMMLHPRWLEMSARAMPLTDTEFQHRYEKALPGVRITKDLIPTM
                     SAAVWDAP"
     aSDomain        1829..2137
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_lzrM1_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="3.50E-10"
                     /label="lzrM1_oMT.1"
                     /locus_tag="lzrM1"
                     /protein_end="140"
                     /protein_start="37"
                     /score="30.3"
                     /tool="antismash"
                     /translation="PAGRRAIDVGCGGGNNCGLLADRYDEVVGLDISQKMLDIAAAKPT
                     RVPVRYVCREALSLSPERDGRFDLVMSVNAVFHMGPVDQVLPVLRDLVAPGGRLVIVD"
     gene            complement(2407..3591)
                     /gene="lzrP"
     CDS             complement(2407..3591)
                     /codon_start=1
                     /gene="lzrP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 348.3; E-value:
                     8.8e-106)"
                     /gene_kind="biosynthetic-additional"
                     /product="RebP-like cytochrome p450"
                     /protein_id="AKQ20689.1"
                     /sec_met_domain="p450 (E-value: 8.3e-17, bitscore: 51.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTLPPFDLRDWADADVRDPYPVFERYLAESPVHVADGTYYVFG
                     HAAASTVLSSPVFGRRSGSGGPIPPGHSVLRTMVENWLVFLDPPRHTELRSVLNREFSP
                     SVVTNLRDRITAIARDLLAGLPAEFDLVERFAAPLPILVISELLGVPRQRWDWLRDQAV
                     ALQEGSSSRAARNPDAHKIAEAAARELHAFFSALADERRAVPGADLVSLMVSAQTRGEP
                     LSSDEIVATCVHLMTAGHETTTNVFSKAVLTLSSRPEALAALRSGVTAAAVEELVRFDP
                     PAQAISRWAYEDTTVAGVEIPRGSKVMVMLGAANRDPARFTSPGTLELDRAGGRSVSFG
                     LGIHYCLGATLARVELEIGLGLLLAALGEFTVVDVEYPYDMVFHGPSKVVVRRV"
     gene            complement(3588..5255)
                     /gene="lzrC"
     CDS             complement(3588..5255)
                     /codon_start=1
                     /gene="lzrC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 333.4; E-value:
                     4.6e-101)"
                     /gene_kind="biosynthetic-additional"
                     /product="RebC-like monooxygenase"
                     /protein_id="AKQ20690.1"
                     /transl_table=11
                     /translation="MGPSAVDDYEAVTPLPGKGNQMTSQLTTDVLVVGGGPIGMAMALE
                     LRYRGVGFVLVEAGDGAVGHPKVSSIGPRSMEFFRRWGVADRIRHSGWPGDHPLDCVWT
                     TRIGGHELFRLHRHTMDTRPDFRHTPEPDAICPQHWLGPLLREELGVHPDGPVRMRTRM
                     DGFTQDADGVTATITDLATGEVTEVRARYLIACDGTGSPIRKTCGIPAPAAHETQVFRN
                     VLFRAPELRARLGERNANFYYLMISSALRFPLRALDGKELYRLTVGLQGHPESLQDAET
                     LVRKAIAFETPVEVLSDNEWHLVHRVASDFRAGRVFLVGDSAHTLSPSGGFGMNTGICG
                     AADLGWKLAAELAGWAGPGLLDSYTAERRPVAFEGLEEANRNLERAMRREVPDELNDDT
                     PRGEFLRGKIREGLQCGGVAREFDAPEIHLGFTYAGSPLIVPDPTAEQTDDRRPNTRPG
                     SRAPHAWIKPGMSTLDLFGDGFVLLCFAESGRLNGFASAFAERGVPFTVVTSDDVEVAE
                     VYERPFVLVRPDGHVAWRGHELPASAGEIVDQVRGGAR"
     gene            5433..6197
                     /gene="lzrY1"
     CDS             5433..6197
                     /codon_start=1
                     /gene="lzrY1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /product="putative alpha/beta hydrolase"
                     /protein_id="AKQ20691.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-11, bitscore:
                     35.2, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.2e-09, bitscore: 27.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSTAETQQRTTVRTHDGLRLAGTLVAPEPEPKRAVLLLHGEGS
                     TSDQGGFYARLSAELAERGVASLRFDLPGHGDSEGRQEDLTLSGLLNTIGAGLAHLRDH
                     VTAAPATLLATGLTGGVAAGYAARRGQEVDRLVLINPLIDYQEHFADSRPGWPAELCAS
                     DRLRVSPTFAVGRAMLNEVFWLQPRGALGAIAAPTLIIHGAGPTTVPLTSSQTAAEALT
                     CASRLVEINGPQAPHWQAPAIREVTEWILPAR"
     gene            6176..6403
                     /gene="lzrY2"
     CDS             6176..6403
                     /codon_start=1
                     /gene="lzrY2"
                     /product="putative alpha/beta hydrolase"
                     /protein_id="AKQ20692.1"
                     /transl_table=11
                     /translation="MDPPGTVTQKKGELSSGNESSPFPRQAFSRQAETGQAAPDALTCT
                     SHLVEINGPQAPHWQAPAIREVAEWILPGR"
     gene            complement(6469..6948)
                     /gene="lzrF"
     CDS             complement(6469..6948)
                     /codon_start=1
                     /gene="lzrF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 119.6; E-value: 1.7e-36)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative flavin reductase"
                     /protein_id="AKQ20693.1"
                     /transl_table=11
                     /translation="MKPSFRSLMAGFPTGVAVLTTFDLDDTPRGMTISSVCSVSMDPPT
                     LLVCVRNGSPTLSALLRSGSFTVNLLHHAARPVAELFCSGEPDRFSRVSWERPALGGPH
                     LVRDAHAVADCVVSQTQEVGTHVVVFGEVREVTHRSAQQPLLYGMRQYAAWPVSA"
     gene            complement(6945..7439)
                     /gene="lzrT1"
     CDS             complement(6945..7439)
                     /codon_start=1
                     /gene="lzrT1"
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 126.8; E-value:
                     1.6e-38)"
                     /gene_kind="transport"
                     /product="putative cation/H+ antiporter"
                     /protein_id="AKQ20694.1"
                     /transl_table=11
                     /translation="MALVAGNGVHALGLTPIFGAFLAGLMIPKGPAWERVAGLIGGTGR
                     VFVPVFFVVAGMTLATGGIGALPWSGVVLAVLLGIAGKVGGGYLGARWGGEDRLTSVRI
                     GVLVNTRGLTEIVVLQVGYTAGLLTPGLFVALLVMALVTTTLTGPLLDLIVRRRVLLEV
                     R"
     gene            complement(7397..8164)
                     /gene="lzrT2"
     CDS             complement(7397..8164)
                     /codon_start=1
                     /gene="lzrT2"
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 99.7; E-value:
                     2.7e-30)"
                     /gene_kind="transport"
                     /product="putative cation/H+ antiporter"
                     /protein_id="AKQ20695.1"
                     /transl_table=11
                     /translation="MQNFLHLVALLAALFAVAAAGRFLARLLRLPSVIGEIALSVLLGP
                     VLLHAFGPAVFAAVLPADVMGLLRHVGEAGLVLFLVGIVHQLDHGVNGLRGKAVGRITL
                     GAFALPLLTGLVFAAWVLWLAPAEVRGTADAGALVLMLAVAMSVTAVPVLARIVEERRA
                     ELGRSADLSMMASMLIDTPAWLLLAVALGLAAGGLGGVWVALAAIAAGGMLAFLGFRLL
                     GRLDVRASTYRGSSRGCSGWWRSWPATGCTRWG"
     gene            complement(8177..9715)
                     /gene="lzrH1"
     CDS             complement(8177..9715)
                     /codon_start=1
                     /gene="lzrH1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 42.2; E-value: 1e-12)"
                     /gene_kind="biosynthetic-additional"
                     /product="tryptophan-5 halogenase"
                     /protein_id="AKQ20696.1"
                     /sec_met_domain="Trp_halogenase (E-value: 8.9e-142,
                     bitscore: 463.3, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKSVVIVGGGTSGWMTASYLTAAFGDRIEVTLVESARVGAIGVG
                     EATFSTVRHFFEYLGLEEKDWMPACNATYKLAIRFENWREEGHHFYHPFERQRVVDGFT
                     LPDWWLRNPSSDRFDRDCFLVGTLCDSLKSPRHLDGTLFEGGLGERSTYRTTLSEQSTQ
                     FPYAYHFDATLVANFLRDYAVARGVRHVLDDVVDVALDSRGWISHVVTKERGELAGDLF
                     IDCTGFRSLLLGKALEEPFESYQSSLPNDSAVALRVPLDMERKGLRPCTTATAQEAGWI
                     WTIPLFDRIGTGYVYASEYSTPEQAEQRLREFVGPAAEGLEANHIKMRIGRSRRHWVNN
                     CVAIGLSSGFVEPLESTGIFFIQHGIEQLVKHFPDVSWEDGLRDSYNNLVNRCMDGVRE
                     FLVLHYYAAKRADNQYWQDTKNRALPDGLAERLERWKTRLPDAESVYPHYHGFEAYSYV
                     CMLLGLGGVELKPSPALGLLDPSSAQHEFKLVAEQATELERTLPTQYEYFARLR"
     gene            complement(9752..10753)
                     /gene="lzrM3"
     CDS             complement(9752..10753)
                     /codon_start=1
                     /gene="lzrM3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 289.6; E-value:
                     5.6e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="O-methyltransferase"
                     /protein_id="AKQ20697.1"
                     /transl_table=11
                     /translation="MTPLAHRMMQMITGYWVTQIVHALAELKIADHLADDRLTAGELAA
                     LTRSDADAMFRLLRAAASLELASYDGDGRFGSTPLLEMLREGVPHSLRDIAIVNGSPAH
                     WLSWGRFPDAVRAGEPQTKAALGSDVWAYFAANPEEFELFSRSMTELSEGLCHEIAELL
                     DTTGVATAVDVGGGNGTLLHALMKSDADLRGVVLDLPGVAPTAIAAADEAGLSDRCEFV
                     GGSFFDTVPEGDLFLLKAVLHNWADDSCVEILTRCREAMRPGGRVVVVEMPLGPVGEPG
                     FAPLLDLNMLAVVPGRERDLAHYDALFAAAGLRRANLTPTRSPQSLIEAVAE"
     gene            complement(10750..12003)
                     /gene="lzrX2"
     CDS             complement(10750..12003)
                     /codon_start=1
                     /gene="lzrX2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 217.6; E-value:
                     5.6e-66)"
                     /gene_kind="biosynthetic-additional"
                     /product="monooxygenase"
                     /protein_id="AKQ20698.1"
                     /transl_table=11
                     /translation="MTRREHTTVCVAGGGPAGAMLGLLLARSGVDVVVLEKHADFHRDF
                     RGDTVHPATLQILDELGLAERFHELPHQKVATIGVVQDGRRIDIADFRRLRVRYPYMAF
                     VPQWDFLDLITTEAARYPGFRLMMSTEVLGVVREDGRVAGVRARGPQGEFEVRSTLVVA
                     ADGRHSAIRGDVGVTPRQIGKSLDVIFFRLSRRDTDPDEGLCVRVGNGKVFGATDRRTY
                     WQMFTETTKGGYEKVRRDGLDAFRADLAAAVPFLADRVHEVSSWDDLKLLEARIDRLDR
                     WHRPGLLFIGDAAHAMSPVAGFGVNLAVQDAVATANALVAPLLTTQLTGAAFDDSLLAA
                     VQRRRRLTTTLSQGLQRATQRFGIDEALDGSGQPPAPKLFEWFAPAQWLMSRVIGLGFR
                     PEHVRTPVTAQLPEGKTS"
     gene            complement(12008..13600)
                     /gene="lzrH2"
     CDS             complement(12008..13600)
                     /codon_start=1
                     /gene="lzrH2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 32.8; E-value: 7.4e-10)"
                     /gene_kind="biosynthetic-additional"
                     /product="tryptophan-6 halogenase"
                     /protein_id="AKQ20699.1"
                     /sec_met_domain="Trp_halogenase (E-value: 2.8e-165,
                     bitscore: 540.8, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDHRIRKVVVLGGGTAGWMTASYLGKALGPDVALTVLEAPSIPK
                     IGVGEATVPNLHRTFFDFLGLAEDEWMRECNASYKMGVRFINWRTPGAGEAKARELRGK
                     PDHFDHLFGLLPNHANLPLSHYWTAERLAGRTDEAFDYACYRESPVLDAALAPRHADGS
                     RWTNYAWHFDAHLVADFLRRFATERQGALHVEDEMTEPVIDHRGHITALRTKSGRLIEG
                     DLFVDCSGFRGLLINKAMREPFLDMSDHLLNDSAVATAVPHDDEANGVEPYTSAIAMSH
                     GWTWKIPMLGRFGTGYVYSSRFTSPDEATKELCDMWGLDPETQPLNHVKFRVGRNRRTW
                     VRNVVSIGLSSCFLEPLESTGIYFITAALYQLAKHFPDKRFDPVLADSFNREIETMFDD
                     SRDFLQAHFSLAPRQDTVFWRSCKELELAENFKGKLAAYRAGLAVNMPAVDETTYYANF
                     EAEFRNYWTNSSYYCIFAGLDYLPEHPLPLLDQRGDLVAGAEPVFAEMKRKQKELLAGL
                     PTHYDHLRRLHGR"
     gene            13801..15237
                     /gene="lzrO"
     CDS             13801..15237
                     /codon_start=1
                     /gene="lzrO"
                     /product="RebO-like L-amino acid oxidase"
                     /protein_id="AKQ20700.1"
                     /transl_table=11
                     /translation="MQGMSARKKVTVLGAGMAGLVAAHELEQLGHEVEVIEGSGRLGGR
                     VYTHRFGAGPSAPLVELGAMRIPAQHRHTLAYVEKLGLSHKLREFKTLFSDDSAYHHTR
                     TGFVRVREAAKALVADYREFLGEGLREETVLFGAWITAIGDAIAPGSFMESLRPDFAAL
                     LEAVDRIDLTPFLVGEGRDQVDLHAFFAAHPEVRQSGTGRINHFIGDILDETSPGLMRL
                     EGGMDQIVDALASRISGPIRLHHEVRGIAVHDDHVAVTVSNGQREIVLRCDHVLSAIPF
                     SVLRKLELSGFSDDKLAVLDEVTHWPATKIAFLCRDAFWQRDGITGGASYGGGHIRQTY
                     YPAVEGDPARGAALLASYTIGADAAVLDDMPEAQRHELVLGEVATMHPELLEPGMMVEA
                     VSQPWGKHPWSAGAGVLRWNKDEAACLEERDRAARPERGRLFFAGEPCATVTGWIDGAI
                     ESALRAVRFIEQAEIPESVR"
     gene            15234..18167
                     /gene="lzrD"
     CDS             15234..18167
                     /codon_start=1
                     /gene="lzrD"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /product="RebD-like chromopyrrolic acid synthase"
                     /protein_id="AKQ20701.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1315.8,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFDLPRLHFAGVAITRLPTGPRNGFVDLATHTALMDGEPFPRD
                     RPAADYHAYLERVDGKGDSFGANGTFAIDAAITAVELVAGDVRTDDVLIGRAVDVWGHY
                     NEYLATTFNRARIFDLDPASDSTTTVMIGQFGFGRLGRSHDVEYMFSGGVHGVQPPRWQ
                     EDGRVLHQFVVHAGEEMIWLGSAADSPAVARLRELVETGAADGLVVQFTMADPAPAPMP
                     NAKAWQLRGTIAPWHSCEPETSPAGRLLTPHHLTVDLRDDHASLNLISFRAPEGVTDLQ
                     LRAARSDTLLASVPADTGHGIVTVPCQPSDEPLCLVGIKAGERVVVAREEEVTVVVDEA
                     SLFLEHPREVEDSSQDVTVAVRTFVRGIPAGVPAVHIRQFFNPRAVPLDQREHIDVVLL
                     SADGAEWAPECVISTDSRGRGQFVVRGAEAGTTSLELGDGGSMAVRVLPDHWWMDDIPQ
                     DEVTFDLLYREVFSFYELMYSFMAEEVFSLADKFRIDTYYQITWQMCDPRNRTKTYYMP
                     QTRDLTGPQARLLLKYLRARRAEVAVPTIEPSLARSDRPISTRAELIRALRHGVTIELA
                     VMLQYLYAAYSVPTYGAGEELVRRGDWTPEQLTLMCGDGGETRDGGLRASLMEVAREEM
                     IHFLVVNNVLMAAGEPFYVPDIDFGTLNDTLPVPLDFSLEALNLGSVQRFIQIEQPEGL
                     TGAVRLGDLPAPTPSEEDYHYASLSELYGDIREGLQRVPDLFLVDKGRGGGEHRLFLRE
                     SVNARHPDYVLEVDDLSSALFAIDFVTEQGEGHVLSEEDTGEESHYDTFVRIADLLMRE
                     RLTATEKGRAQWNPAYPVARNPTLHEGRHAKELVTDPVARELVALFNGSYFMVLQLMVQ
                     HFGDPDASLRRSRFMNTAIDVMTGVMRPLAELLVAVPSGRHGRTAGPSFELDEQPAFIP
                     RPDVARRSLSLRFRRLLEAARKCDLVPGKVVGNLEHFAEQFAAGPVS"
     gene            complement(18160..19257)
                     /gene="lzrG"
     CDS             complement(18160..19257)
                     /codon_start=1
                     /gene="lzrG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 363.5; E-value:
                     2.2e-110)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome p450"
                     /protein_id="AKQ20702.1"
                     /sec_met_domain="p450 (E-value: 8.3e-30, bitscore: 94.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQIQLPDGKKVWLVSDYAGTRSVLTDSRLTNDPLRMGDKAPFSA
                     FPESIASVMAHDMLNNDPPAHTRLRRLVTPTFTVRRIADHRPQVERIAAELIEHFGDRP
                     DLVRDFAGPLATKVLGLMLGIDPADAARVRYWSDLFVLDLLTRNEEAMDATHRLAEYTR
                     GLVDERRRNPGDDLVSRLVSMRDDEERLDDHELASMVFTLVIGGQTATTQLLAKALYLL
                     LNHPDQLELLLADWSLLPSAVHEVLRIDPPLQMTSFRMATEPFEFDGKTVQQGDIVVCA
                     LREANRDPVRFTDPERFDLRKGDGQHLGFGHGVHRCIGANLAELQCQVGLTAFFRRFPH
                     AKPGEAEWRQTPLITAISALPVHLS"
     gene            complement(19690..22533)
                     /gene="lzrR"
     CDS             complement(19690..22533)
                     /codon_start=1
                     /gene="lzrR"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 236; E-value: 1.5e-71)"
                     /gene_kind="regulatory"
                     /product="LuxR-type transcriptional regulator"
                     /protein_id="AKQ20703.1"
                     /transl_table=11
                     /translation="MKRRILEELTDSAIPETSLTWSLHGRATQVGRVEQLMRDSVEEQR
                     SHVVVLESGAGTGKTRLLLELMSCAARRGFAVVNGAADQPGLARAVTLVNPRNGRQEDD
                     RIGTLAGRFEAQLTGHLRRGPVLVAVDDVQWTDLALLHALGAVVSKLDSCPVVWLFAVH
                     ADHTDSPNGVVLRTLARKHRAEWLGPLEPLTGEAVAGIAGDLLDATPDDDVLALCESVG
                     GTPQAIVDLVLDVRREGCVTVTDQVARLASGPMPTGISSAVEPDPGAPLPRPFVRLMQS
                     RLRELSPRAQEVLQVAAVLGSSFAPQDLAEMLGERPAQLLGPLQEALTAGLIGSDSDEF
                     VFRREPVWRAVLGTVPEVLRSMLHRQAATMLLDRPQGRIETAAVHLVHCAMPGDAEAIG
                     TIRAAAERMLAGSPQAASALATRGLRIAPPDSADHAALATTATAALVRLGCLSDAVELA
                     EEQLRVHTCPELTRPLRTWLATALMLRGDTAAAFHVSNETIADAQSPANSLSADTEPCP
                     ELLLLNALCHNDQSRVVAVADRVLDVPGERSDEVRAAALNVRAMAYWREGRLDAAMNAV
                     DEAVRLRGPLTRAWQSDPLWTRAWLLTRVRRLDEALAAADAARRAIDTEHNGVLSPVPL
                     ALRATILLAKGDLAAAESDATAGLTASERAEMPLYEPQLHAVLVISALRRGDLATASDG
                     LRRLEECAPAERAQPWTPLVRVLSALVTSARRDVHAAMEELREPLADPGQRRQLLLEDP
                     SMTAWVVRTALAADAREIAEGVVVAAEKIAAENQRYVTIVAAARHGRALLDSDVSALSG
                     LEERYGDPWAAASVIEDTGTLLRDTDRDHAVAELNRAMAAYDELGAEWDSARVRRKLRR
                     LGVRRRHWNHEVRPETGWGSLTSTEAKVARLVARGLTNRQVASEMFVSPHTVGFHLRQI
                     YRKLSIQSRVDLARIAP"
ORIGIN
        1 ctaccggatc gcctgaacgc gggtcagcac cgagtccagg aactcgatca gcgtgtccac
       61 cgaaccggga tcggccaccg cggcgacgtg cccgtccggc cgcaccagca ccagccgcgg
      121 accgtccact ttgtacgccc ggtgcgcggc ctcctcggac ggcgagatga cgtgcgtggt
      181 cacggcagcg gcgtagcggc cgtcgaaccg cgcagccacc acctccggct gaggaaccga
      241 gaacagcaac acgtggtagc cggtgccgtg ggtcaggtcg agcacgctgc ccgtcccgag
      301 cggtgcgtag ggcgcacggg cgcccggctt cagctggccg acgccccgac cgaccgcgcg
      361 gctgccccgg tacccgatcc acaactggga gaacatgtgg aagaacatcc gccgcaccgg
      421 cgcaagccgt gagaccgcac cgatgatccg agtcgcgacg tgcgcgcgca tccacacggc
      481 cagcgcgttg ttcccggtct ccagtttgaa cccgaatcgg tccgccgcag caccgtccgc
      541 gcgatcggcc gccgctcggc ctcgtaggtg tcgagcagcc accgcggtgc ctcgccgtgc
      601 acgacctggg cgagcttcca cgccaagttg atcgcgtcgc ccacgcccag gttcaggccc
      661 tgaccaccgg ccgggttgtg gatgtgcgcg gcgtcgccga ccaggaaggc gttgcccacc
      721 cggaacttcg ccgcgagccg gctgtgcacg cggaacatcg acgcccagag gatctcctcc
      781 agccgggcgt ccaccttgaa gtagtcgtcg aaccacagct gcaggtcggc gtggtccagc
      841 ggtgcgtacg actcgtgcga cacggcggcc ggccggggcg aattgtgcag ttccggcggt
      901 accacgccga acagccggta gcggccgctg cgcagcggca ggatgccgac gaaaccaccg
      961 cgggtcaggt tgagccgcat gcctttcacg ccgagcgaca cgtccagcgt cacgtcggcc
     1021 agcaggccgg cctggtcgta ggtctcgccg tcgaactcct gcccgaggaa cttccgcacg
     1081 ctgctcgacg caccgtccgc gccgaccagc catcgcgcgg agatcacgtc gcccgcagtc
     1141 tgcaccgaga ccccggatcc ggtgtcggcc acgcccgtga cctcggtgcc ccactcgacg
     1201 gcgacggcgt gctcgccgag cgcgttcacc aacaggcgtt ccatctcgaa ctgctcgagc
     1261 gcgagcgcgt acggaaaccg cgtctggtcg gcggttccct cgcccgcgag cgacatctca
     1321 cccgcgtgac ggccggacga gtggatctcc acctcggtga tcggcaggcc gcgcgcgacg
     1381 gccgtctcgg cgacccccag gcgatccagg agctccagcg tccgcgcgtg cacgatggtg
     1441 gcccgcgtct gctcaaccgg accgggcctg cggtcggcga tccggacccg cacaccgtgc
     1501 tgggccagca tcagcgcagt gcacagcccg gtgggaccgg cccccaccac gagtacgtcg
     1561 cagtcgtgtt cgtcgcgcat gagttccagt gtcgcgagaa agcctcgtcg tccacatcgc
     1621 ccggcacggg cggtgacggt gccaccaccc cgcacgtgtg cgcaggttct gcgcgggccc
     1681 ctgttcgcgc ccgccaccac cgtcgaaagt gcgtctcatg agcgcaccgg aagcctattt
     1741 cgacgatctg gccgagctgt acgagcggtt caccggcatc cgcgatgccg cgacgagccc
     1801 ggtccgctcg tggctgatcg agcagttgcc ggccggcagg cgggcgatcg acgtcggctg
     1861 cggcggcggc aacaactgcg gcctgctcgc cgaccgttac gacgaggtcg tcggcctcga
     1921 catctcccag aagatgctgg acatcgcggc cgccaagccg acgcgcgtgc cggtgcggta
     1981 cgtgtgccgc gaagcgctga gcctctctcc cgagcgcgac ggacggttcg atctggtgat
     2041 gtcggtcaac gcggtcttcc acatgggccc cgtcgaccag gtgctgcccg tgctgcgcga
     2101 tctcgtcgcc cccggaggcc ggctggtgat cgtcgatgtg acgctgcccg acggtgccgc
     2161 cgcgtcggcc gagcagagcg cctacgcgtt cgagaccggc aagatcatct acgacgtctc
     2221 cggtgacgtc gaggccgcgt gcgactcgat caggatgatg ctgcacccgc gctggctcga
     2281 gatgagcgca cgggcgatgc cgctcaccga caccgagttc cagcaccggt acgagaaggc
     2341 gctgcccggc gtgcggatca ccaaggacct catccccacc atgagcgccg ccgtctggga
     2401 cgcgccctaa acgcgtcgca cgacgacctt ggacggtccg tggaagacca tgtcgtacgg
     2461 gtactccacg tcgaccacgg tgaactcgcc gagcgcggcc agcagcaacc cgagcccgat
     2521 ctccagttcc acccgtgcca gcgtcgcgcc gaggcagtag tggatgccca gcccgaaact
     2581 cacgctccgg ccacccgccc ggtccagctc cagcgtgccg ggcgaggtga accgggcggg
     2641 gtcgcggttg gccgcgccga gcatcaccat caccttgctg ccgcgcggga tctcgacccc
     2701 ggccacggtg gtgtcctcgt aggcccaccg gctgatcgcc tgcgcgggcg ggtcgaagcg
     2761 caccagctcc tccacggccg ccgcggtcac gccggatcgc aacgccgcca acgcctccgg
     2821 ccgtgacgac aacgtcagca ccgccttgct gaacacgttc gtcgtcgtct cgtgccccgc
     2881 ggtcatcagg tgcacgcacg tcgccacgat ctcgtccgac gacagcggtt ccccacgcgt
     2941 ctgcgcggac accatgagcg acaccagatc cgcaccggga accgcgcgcc gctcgtccgc
     3001 cagggcggag aagaaggcgt gcagttcgcg tgccgcggcc tcggcgatct tgtgcgcgtc
     3061 ggggttgcgg gcggcacggc tactactccc ctcctggagg gcaacggcct gatcgcgcaa
     3121 ccagtcccac cgctgccgcg gcaccccgag cagttcggag atcaccagga tcggcaacgg
     3181 tgccgcgaac cgctcgacga ggtcgaactc cgccggcaga ccggccagca gatcgcgcgc
     3241 gatggccgtg atccggtcgc ggaggttcgt caccaccgac ggcgagaact cccggttgag
     3301 cacggaccgc agctcggtgt gccggggcgg gtcgaggaag accagccagt tctccaccat
     3361 cgtgcgcagc accgagtgcc caggcgggat cggcccgccc gaccccgacc gccgcccgaa
     3421 gacgggactg gacaacacgg tcgacgcggc ggcatggccg aagacgtagt aggtgccgtc
     3481 agcgacgtgt accggcgact ccgcgagata gcgctcgaac accgggtagg ggtcgcgcac
     3541 gtcggcgtcg gcccagtccc gcaggtcgaa cggaggcagc gtcgtggtca ccgcgcacca
     3601 ccacgaacct ggtcgacgat ctccccggcc gacgcgggca gctcgtggcc gcgccacgcc
     3661 acgtgcccgt ccggccggac caggacgaac ggccgctcgt agacctcggc cacctccacg
     3721 tcgtccgagg tgacgacggt gaacgggaca ccgcgctcgg cgaacgcgct cgcgaacccg
     3781 ttcagccggc cggactccgc gaagcacagc agcacgaagc cgtcgccgaa caggtccaaa
     3841 gtggacatcc ccggcttgat ccacgcgtgc ggtgcgcgcg accccggccg ggtgttgggc
     3901 ctgcggtcgt cggtctgttc cgcagtcgga tccggcacga tcagcggtga ccccgcgtag
     3961 gtgaagccga ggtggatctc cggtgcgtcg aactcgcggg ccacgccacc gcactggagt
     4021 ccttcccgga tcttgccccg gaggaactca ccacgtggcg tgtcgtcgtt cagctcgtcc
     4081 gggacctccc gccgcatcgc gcgttccagg ttgcggttgg cctcctccag tccctcgaag
     4141 gcgaccggcc tgcgctcggc ggtgtagctg tcgagcagcc cgggaccggc ccagccggcc
     4201 agctccgccg ccagcttcca gccgaggtcc gccgcaccgc agatgccggt gttcatgccg
     4261 aacccgccgg acggcgacag cgtgtgcgcg gagtcgccga cgaggaagac ccggccggcc
     4321 cggaagtccg acgcgacgcg gtgcaccagg tgccactcgt tgtcggacaa cacctccacc
     4381 ggggtctcga acgcgatggc cttgcgcacc agcgtttccg cgtcctgcaa cgactccggg
     4441 tgcccctgca ggccgacggt gagccggtag agctccttgc cgtccaacgc gcgcaacggg
     4501 aaccgcagcg ccgaggagat catcaggtag tagaagttcg cgttgcgctc gccgagccgg
     4561 gcccgcagct ccggcgcgcg gaacaggacg ttgcggaaga cctgggtctc gtgcgcggcg
     4621 ggcgccggga tgccgcacgt cttgcggatc ggggatcccg tgccgtcaca ggcgatcagg
     4681 taccgggcgc gcacctcggt cacctcgccg gtggccaggt cggtgatcgt cgccgtcacg
     4741 ccgtcggcgt cctgggtgaa cccgtccatc cgcgtgcgca tccgcaccgg cccgtccggg
     4801 tgcacgccga gctcctcgcg cagcaacggc cccagccagt gctgcgggca gatcgcgtcc
     4861 ggttccgggg tgtgccggaa gtccggccgc gtgtccatcg tgtgccggtg cagccggaac
     4921 agctcgtggc cgccgatgcg ggtggtccag acgcagtcca gcgggtggtc ccccggccag
     4981 cccgagtgcc ggatccggtc ggccacgccc cagcgccgga agaactccat cgagcgcggg
     5041 ccgatgctgc tgaccttggg atgaccgacc gctccgtcgc cggcctccac caggacgaag
     5101 ccgacaccgc ggtagcgcaa ctccaacgcc atcgccatgc cgatcgggcc accgccgacg
     5161 acgagcacgt cggtcgtgag ctgggaggtc atctggtttc cctttccggg caacggcgtc
     5221 acggcctcat agtcgtcaac ggccgatggg cccacatccc cttcccccgg cccgcgatgg
     5281 acggtttgtg gtacccgcac cccgcgcgat cgcgtcggga aacggcttca caccgcgcga
     5341 gccaacggga tctctcgcgc gtgcgtgggc gatcccatta cgcgggcaac actgacgcgc
     5401 acacccccgt cggaggaaga caggagtccg cgatgcccac gagcaccgcc gaaacccagc
     5461 agcgcaccac cgtgcgcacc cacgacggcc tgcgcctggc cggcacgctg gtcgcaccag
     5521 agcccgaacc gaagcgcgcg gtgctgttgc tgcacggtga gggatcgacg agcgaccagg
     5581 gcggcttcta cgcgcggctg tccgccgagc tcgccgaacg cggcgtggcc agcctgcgct
     5641 tcgacctgcc gggccacggc gacagcgagg gccgccagga ggacctgacc ctgtccggcc
     5701 tgctgaacac catcggcgcc ggactggcgc acctgcgcga ccacgtcacc gccgcaccgg
     5761 ccaccctgct cgccaccggg ctgaccggcg gggtcgcggc cgggtacgcc gcgcgcaggg
     5821 gccaggaggt ggaccggctg gtgctgatca acccgctgat cgactaccag gagcacttcg
     5881 ccgactcccg tcccggctgg cccgccgagc tgtgcgcgag cgaccggctg cgggtctccc
     5941 ccaccttcgc ggtgggcagg gcgatgctca acgaggtgtt ctggctccag ccgcgcggtg
     6001 ccctgggcgc catcgccgca ccgacgctga tcatccacgg agcggggccg acgaccgtcc
     6061 cgctgacgtc ctcccagacc gctgccgaag cactcacgtg cgcaagccgc ctcgtcgaga
     6121 tcaacggtcc gcaggccccg cactggcagg ctcccgcgat ccgcgaggtg acggagtgga
     6181 tcctcccggc acggtgacgc aaaaaaaggg ggagctttcg tccggcaacg agagctcccc
     6241 ttttccgcgc caggcctttt cgcgtcaggc ggaaaccggc caggccgctc ccgacgcact
     6301 cacatgcacc agccacctcg tcgagatcaa cggtccgcag gccccgcact ggcaggctcc
     6361 cgccatccgc gaagtcgcgg agtggatcct cccgggacga tgacgcgaca acaaggggag
     6421 ctctcgtcca acgacgagag ctccccttgt cgcgtcaggc ctttcgcgtc aggcggagac
     6481 cggccaggcc gcgtactgcc gcatcccgta cagcagcggc tgctgggccg accggtgcgt
     6541 gacctcgcgg acctcgccga acaccacgac gtgcgtcccg acctcctgcg tctgggaaac
     6601 aacgcaatcc gccacggcgt gggcgtcgcg cacgaggtgc ggcccgccca gcgccggtcg
     6661 ctcccaggac acccgcgaga accggtccgg ctcacccgag cagaacagct ccgccaccgg
     6721 ccgggccgcg tggtgcagca ggttgaccgt gaaggaaccg ctgcgcagca aggcggacaa
     6781 cgtcgggctg ccgttgcgca cgcacaccag caacgtcggc ggatccatcg acacgctgca
     6841 caccgatgag atcgtcatgc cgcgcggggt gtcgtcgagg tcgaacgtcg tcagcacggc
     6901 gaccccggtc gggaacccgg ccatcagcga ccggaacgag ggtttcatcg gacctccagg
     6961 agcacccggc gacggacgat cagatcgagc agcggcccgg tcaacgtggt cgtcaccagc
     7021 gccatcacca gcagcgccac gaacaacccc ggcgtcagca agccagcggt gtagccgacc
     7081 tggagcacca cgatctcggt gaggccgcgg gtgttgacca gcacgccgat ccgcaccgac
     7141 gtcagccggt cctcgccgcc ccaccgagcc ccgaggtatc cgccgccgac cttgcccgcg
     7201 atcccgagca gcaccgccag cacgaccccg gaccacggca gggcgccgat cccgcccgtc
     7261 gccagcgtca tgccggccac cacgaagaac accgggacga acacccgccc ggtcccgccg
     7321 atcagtccgg ccacgcgctc ccacgccggg cccttcggga tcatcaggcc ggccaggaac
     7381 gcaccgaaga tcggcgtcag ccccagcgcg tgcaccccgt tgccggccac gagcgccacc
     7441 agcccgagca gccccgcgaa gatccgcggt aggtgctcgc ccggacgtct aaccggccga
     7501 ggagccggaa cccgaggaac gccagcatcc cgccggccgc gatggccgcg agcgccaccc
     7561 agacaccgcc gagtccaccg gcggcgagcc cgagggcaac ggccagcagc agccacgcgg
     7621 gcgtgtcgat cagcatcgac gccatcatcg acaggtccgc ggaccggccg agctccgcac
     7681 ggcgttcctc gacgatccgc gccagcaccg gcaccgcggt cacgctcatc gcgacggcca
     7741 gcatgagcac cagcgcgccc gcgtccgccg tgccgcgcac ctcggccggt gccagccaca
     7801 gcacccacgc cgcgaacacg agcccggtca gcagcggcag ggcgaacgcg ccgagcgtga
     7861 tccgcccgac cgccttgccg cgcaacccgt tcaccccgtg gtcgagctgg tgcacgatgc
     7921 ccaccaggaa cagcaccagc ccggcctcac cgacgtgtct cagcaggccc atgacgtccg
     7981 cgggcagcac ggcggcgaag acggcggggc cgaacgcgtg caggagcacc gggccgagca
     8041 ggacgctcag cgcgatctca ccgatcaccg agggcagccg cagcagcctg gcgaggaagc
     8101 gccccgcggc cgcgaccgcg aacagtgccg ccagcaacgc gaccagatga aggaagttct
     8161 gcatcgccaa cccttctcag cgcaaccgcg cgaagtactc gtactgcgtg ggcagcgtcc
     8221 gttcgagctc ggtggcctgt tcggcgacga gtttgaactc gtgttgcgcc gacgacgggt
     8281 cgagcaggcc gagcgccggc gagggcttca gctcgacgcc gccgagcccg agcagcatgc
     8341 agacgtagga gtaggcctcg aagccgtggt agtgcgggta gaccgactcg gcgtcgggca
     8401 gccgggtctt ccaccgctcc aggcgttccg cgagaccgtc cggcaacgcg cggttcttgg
     8461 tgtcctgcca gtactggttg tctgcgcgtt tggccgcgta gtagtgcagc accaggaact
     8521 cgcgcacgcc gtccatgcag cggttgacca ggttgttgta cgagtcgcgc aggccgtctt
     8581 cccacgagac gtccgggaag tgcttcacca gctgctcgat cccgtgctgg atgaagaaga
     8641 tgccggtcga ctccagcggt tccacgaagc cggacgacag gccgatcgcg acgcagttgt
     8701 tgacccagtg ccggcgcgaa cggccgatcc gcatcttgat gtggttggcc tccaggcctt
     8761 ccgccgctgg accgacgaac tcgcgcagcc gctgctcggc ctgctcgggt gtggagtact
     8821 cgctggcgta gacgtacccg gtgccgatgc ggtcgaacag cgggatcgtc cagatccagc
     8881 cggcttcctg cgcggtcgcg gtggtgcacg gccgcaaccc cttgcgctcc atgtcgagcg
     8941 gcacccgcaa cgccaccgcc gagtcgttcg gcagtgagga ctggtacgac tcgaacggtt
     9001 cctcgagagc cttgcccagc aacagactcc ggaagccggt gcagtcgatg aacaggtcgc
     9061 cggcgagctc gccccgctcc ttggtcacga cgtgactgat ccagccccgc gagtccagcg
     9121 ccacgtcgac cacgtcgtcg agcacgtgcc ggacgccgcg cgcgaccgcg tagtcgcgca
     9181 ggaagttcgc gaccaatgtg gcgtcgaagt ggtaggcgta cgggaactgg gtcgactgct
     9241 cggacagcgt cgtccggtac gtcgaccgct cccccaggcc gccctcgaac agcgtgccgt
     9301 ccaggtgccg cggtgacttc aggctgtcgc acaacgtgcc cacgaggaag cagtcccggt
     9361 cgaaccggtc cgacgacggg ttgcgcagcc accagtccgg cagcgtgaac ccgtccacca
     9421 cccgctgccg ttcgaacggg tggtagaagt ggtggccctc ctcgcgccag ttctcgaacc
     9481 ggatcgcgag cttgtaggtc gcgttgcacg ccggcatcca gtccttctcc tcgagaccga
     9541 ggtattcgaa gaagtgccgg acggtgctga acgtggcctc gccgacgccg atcgcgccga
     9601 cccgcgccga ctccaccagc gtgacctcga tccggtcacc gaacgccgcg gtcaggtacg
     9661 aagccgtcat ccagcccgac gttccaccgc ccacgatcac aacactcttc agcatgaaag
     9721 gaatcctccg aagtggaacg aacgagccgg ctcactcggc gacggcttcg atcaggcttt
     9781 gcggggaacg ggtgggggtg aggttcgccc gccgcagtcc cgcggccgcg aacagggcgt
     9841 cgtagtgcgc gagatcgcgt tcccggccgg gcacgaccgc gagcatgttg aggtccagca
     9901 acggtgcgaa gccgggctca ccgaccgggc cgagcggcat ctcgacgacc accacccggc
     9961 cgccggggcg catcgcctcg cggcagcggg tgaggatctc gacgcacgaa tcgtcggccc
    10021 agttgtgcag cacggctttg agcaggaaca ggtcgccttc cggcaccgtg tcaaagaagg
    10081 aaccgccgac gaactcgcag cggtcgctca gcccagcctc gtccgccgcg gcgatcgccg
    10141 tcggcgccac gcccggcagg tcgaggacca caccccggag gtccgcatcg gacttcatca
    10201 gcgcgtgcag caacgtgccg ttgccaccgc cgacgtcgac cgcggtcgcg acgccggtcg
    10261 tgtcgagcag ctccgcgatc tcgtggcaca gtccctcgga cagctcggtc atcgagcggg
    10321 agaacagttc gaactcctcc gggttcgccg cgaagtaggc ccacacgtca ctgcccagcg
    10381 ccgccttcgt ctgcggttca ccggccctga ccgcgtcggg gaacctgccc caggacagcc
    10441 agtgcgcggg agagccgttc acgatcgcga tgtcccgcaa cgaatgcggt acgccctcgc
    10501 gcagcatctc cagcaacggc gtgctgccga accggccgtc gccgtcgtag gaggcgagct
    10561 ccagcgacgc ggcggcgcgc aacagccgga acatcgcgtc ggcgtcggac cgggtcagcg
    10621 cggcgagttc gccggcggtg agccggtcgt ccgcgaggtg gtcggcgatc ttcagttcgg
    10681 cgagggcgtg cacgatctga gtcacccagt acccggtgat catctgcatc atccggtgcg
    10741 ccagcggcgt catgaggtct tcccttcggg tagctgcgcc gtcacgggtg tgcgcacgtg
    10801 ttcggggcga aagccgaggc cgatgacgcg gctcatcagc cactgcgccg gagcgaacca
    10861 ctcgaacaac ttgggcgcgg gcggctgccc ggagccatcg agcgcctcgt cgatgccgaa
    10921 gcgctgggtc gcccgctgaa gtccctgcga cagcgtggtg gtgagccgcc tgcggcgctg
    10981 gacggcggcg agcagcgagt cgtcgaacgc ggcaccggtc agttgcgtgg tgagcagtgg
    11041 tgcgaccagg gcgttggccg tggcgaccgc gtcctgcacc gcgaggttca caccgaagcc
    11101 cgcgaccggc gacatggcgt gcgcggcgtc gccgatgaac agcaggccgg gccggtgcca
    11161 gcggtcgagc cggtcgatcc gcgcctccag cagcttcagg tcgtcccacg aggacacttc
    11221 gtgcacgcgg tcggcgagga acggcacggc agcggcaaga tccgcgcgga acgcgtcgag
    11281 cccgtcccgg cgcaccttct cgtagccgcc tttggtggtc tcggtgaaca tctgccagta
    11341 cgtcctgcgg tcggtggcgc cgaacacctt gccgttgccg acgcgcacgc agagaccctc
    11401 gtcggggtcg gtgtcccggc gggagagccg gaagaagatc acgtccagcg acttgccgat
    11461 ctgccggggc gtcacgccga cgtccccgcg gatcgcggag tgccggccgt cggcggcgac
    11521 caccagggtc gaacggacct cgaactcgcc ctgcggcccc cgcgcccgga caccggcgac
    11581 ccggccgtcc tcccgcacca caccgaggac ctcggtgctc atcatcagcc ggaagccggg
    11641 gtagcgcgcg gcctcggtgg tgatcaggtc gaggaagtcc cactgcggca cgaaggccat
    11701 gtacgggtag cgcacccgca gcctgcggaa gtcggcgatg tcgatgcgcc tgccgtcctg
    11761 caccacgccg atcgtggcga ccttctggtg cggcagctcg tggaaccgtt ccgccaggcc
    11821 gagttcgtcg aggatctgca gcgtggcggg gtgcaccgtg tcgccgcgga agtcgcggtg
    11881 gaagtccgcg tgcttctcca gcaccaccac gtccactccg gaccgcgcga gcagcagccc
    11941 cagcatcgcc cccgccggcc cgccaccggc gacgcagacc gtggtgtgtt ctcgtcgggt
    12001 catctgctca gcgcccgtgc agccggcgca ggtggtcgta gtgggtcggc agcccggcga
    12061 gcagttcctt ctgcttgcgc ttcatctccg cgaacaccgg ttccgctccc gccaccaggt
    12121 cgccgcgctg gtcgagcaac ggcaacgggt gctccggcag gtagtcgagg ccggcgaaga
    12181 tgcagtagta gctgctgttg gtccagtagt tgcggaactc cgcctcgaag ttcgcgtagt
    12241 aggtcgtctc gtcgacggcg ggcatgttca ccgcgagacc cgcgcggtac gccgcgagct
    12301 tgcccttgaa gttctccgcc agctccagtt ccttgcagga ccgccagaac accgtgtcct
    12361 gccgcggcgc cagcgagaag tgcgcctgca ggaagtcgcg gctgtcgtcg aacatggtct
    12421 cgatctcgcg gttgaacgag tcggccagca ccgggtcgaa ccgcttgtcc gggaagtgct
    12481 tcgccagctg gtagagcgcc gcggtgatga agtagatgcc ggtggactcg agcggctcca
    12541 ggaagcacga cgacaacccg atgctgacga cgttgcgcac ccacgtgcgg cggttgcggc
    12601 cgacgcggaa cttcacgtgg ttgagcggct gcgtctcggg gtcgaggccc cacatgtcgc
    12661 agagttcctt cgtcgcctcg tccggcgagg tgaagcggct cgagtagacg tagccggtgc
    12721 cgaaccggcc cagcatcggg atcttccacg tccacccgtg gctcatcgcg atcgccgagg
    12781 tgtacggctc gacgccgttg gcctcgtcgt cgtgcggcac ggccgtggcg accgcgctgt
    12841 cgttgagcag gtggtcgctc atgtcgagga acggctcgcg catcgccttg ttgatgagca
    12901 ggccgcggaa acccgagcag tcgacgaaca ggtcgccctc gatcaggcgg ccggacttcg
    12961 tgcgcaacgc ggtgatgtgc ccgcggtggt cgatgaccgg ttcggtcatc tcgtcctcga
    13021 cgtggagcgc gccctgccgc tcggtggcga accggcgcag gaagtcggcc acgaggtgcg
    13081 cgtcgaagtg ccacgcgtag ttcgtccacc gggacccgtc ggcgtgacgg ggcgcgagtg
    13141 cggcgtccag caccggcgac tcgcggtagc aggcgtagtc gaacgcctcg tcggtgcggc
    13201 cggccagccg ctcggccgtc cagtagtgcg acagcggcag gttcgcgtgg ttgggcagca
    13261 ggccgaagag gtggtcgaag tggtccggct tgccgcgcag ctcccgcgcc ttcgcctcgc
    13321 cggcgccagg ggtgcgccag ttgatgaacc ggacgcccat cttgtagctg gcgttgcact
    13381 cccgcatcca ctcgtcctcg gcgaggccga ggaagtcgaa gaacgtcctg tgcaggttcg
    13441 gcacggtggc ctcgccgacc ccgatcttcg ggatggacgg cgcctcgagc acggtgagcg
    13501 cgacgtcagg tccgagcgct ttgccgaggt aggaggctgt catccagccc gcggtgccac
    13561 cgccgaggac gacgaccttc ctgatccgat gatcttccac caggcttccc ttccacgatg
    13621 tgcgcgatcg atctggaagc tagccagcgg cgtcccactt cgaacgcgtg cgatgaagaa
    13681 cccctccgat cacgtggggt cggcgtgcca cgacgcgcgg tgccgccgga ggaacccacg
    13741 cgcaaaccgc ccggaccacg cggggtcgcg tgatgtgccg gtggtggtcg cgccgaaagg
    13801 atgcaaggca tgtcagcgcg caagaaggtc acggttctcg gtgcggggat ggcgggtctc
    13861 gtggccgcgc acgaactcga gcaactgggc cacgaggtcg aggtgatcga gggaagcggg
    13921 cggctcggcg gccgggtgta cacgcaccgg ttcggtgcgg gtccctcggc gccgctggtc
    13981 gagctgggcg ccatgcggat tcccgcacag caccggcaca ccctggccta cgtcgagaag
    14041 ctcggcctgt cgcacaagct ccgcgagttc aagacgctct tctccgacga cagcgcctac
    14101 caccacaccc gcaccgggtt cgtgcgcgtg cgggaggcgg ccaaggcgct cgtggccgac
    14161 taccgggagt tcctgggcga gggcctgcgc gaggagaccg tcctgttcgg tgcgtggatc
    14221 accgccatcg gtgacgcgat cgcgcccggc agcttcatgg agtcgctgcg ccccgacttc
    14281 gccgcgctgc tcgaggccgt cgaccgcatc gacctgaccc cgttcctggt gggcgaggga
    14341 cgggaccagg tcgacctgca cgcgttcttc gcggcccatc ccgaggtgcg gcagagcggc
    14401 acgggccgga tcaaccactt catcggtgac atcctcgacg agaccagtcc agggctgatg
    14461 cggctcgagg gcgggatgga ccagatcgtc gacgctctcg cgagccgcat ctccgggccg
    14521 atccgcctcc accacgaggt gcgcgggatc gccgtgcacg acgaccacgt cgccgtgacc
    14581 gtctcgaatg gacagcggga gatcgtcctc cgctgtgacc acgtgctgag cgcgatcccg
    14641 ttctccgtgc tgcgcaagct cgagctcagc ggcttcagcg acgacaagct ggccgtgctc
    14701 gacgaggtca cgcactggcc ggccaccaag atcgcgttcc tgtgccgcga cgcgttctgg
    14761 cagcgcgacg ggatcaccgg cggggcgtcg tacggcggcg ggcacatcag gcagacctac
    14821 tacccggcgg tggagggcga cccggccagg ggcgccgcgc tgctggcgag ctacacgatc
    14881 ggcgccgacg ccgccgtgct cgacgacatg ccggaagcgc aacggcacga gctcgtgctc
    14941 ggcgaggtcg ccacgatgca tcccgagctg ctcgaaccgg ggatgatggt cgaggccgtg
    15001 agccagccgt ggggcaagca cccgtggagc gccggtgccg gtgtcctgcg gtggaacaag
    15061 gacgaggccg cgtgcctgga ggaacgcgac cgggcggccc gtcccgagcg cggcaggttg
    15121 ttcttcgcgg gtgagccctg cgcgaccgtc accgggtgga tcgacggcgc catcgagtcc
    15181 gccctgcgcg ccgtgcggtt catcgaacaa gccgagatcc cggagagcgt ccgatgagtg
    15241 ttttcgacct gccccgcctg cacttcgccg gcgttgcgat cactcggctg ccgaccgggc
    15301 cgcgcaacgg gttcgtcgac ctcgccaccc acaccgcgct gatggacggc gagccgttcc
    15361 cccgcgaccg gccggccgcc gactaccacg cctacctcga gcgcgtggac gggaaagggg
    15421 attccttcgg cgccaacggg actttcgcca tcgatgccgc gatcacggcg gtcgagctcg
    15481 tcgcgggcga cgtgcggacc gacgacgttc tgatcggccg cgcggtggac gtgtggggtc
    15541 actacaacga gtacctcgcc acgacgttca accgggcgcg gatcttcgac ctggacccgg
    15601 cgtcggactc gacgacgacg gtcatgatcg gccagttcgg cttcggccgg ctcgggcgct
    15661 cgcacgacgt cgagtacatg ttctccggcg gtgtgcacgg cgtgcagcca ccgcggtggc
    15721 aggaggacgg ccgggtcctg caccagttcg tcgtgcacgc gggcgaggag atgatctggc
    15781 tcggcagcgc ggcggactcc cccgccgtcg cccggttgcg cgaactcgtc gagacgggcg
    15841 ccgccgacgg actggtcgtg cagttcacga tggccgaccc cgctccggcg ccgatgccca
    15901 acgccaaggc gtggcagctg cgcggcacga tcgcgccctg gcactcgtgc gagccggaga
    15961 cgtctcccgc cggtcgcctg ctgaccccgc accacctcac cgtcgacctg cgcgacgacc
    16021 acgcctcgct caacctgatc tcgttccgcg ctcccgaggg tgtgacggat cttcagctgc
    16081 gcgctgcccg ttccgacacg ctgctcgcct cagtgcccgc ggacaccgga cacggcatcg
    16141 tcaccgtgcc ctgtcagccg tcggacgaac cgttgtgcct ggtcggtatc aaggcgggcg
    16201 aacgcgtcgt ggtggctcgc gaggaggagg tcaccgttgt tgtcgacgag gcgagcctgt
    16261 tcctggaaca cccgcgcgag gtcgaggaca gctcgcagga cgtgactgtc gccgtccgga
    16321 cgttcgtgcg cggtattccg gccggcgttc ccgctgtcca cattagacag ttcttcaacc
    16381 ctcgcgcggt gccgctcgac cagcgggagc acatcgacgt cgtgctgctg agcgctgatg
    16441 gcgcggagtg ggcacctgag tgcgtgatca gcaccgactc ccgcggccgc gggcagttcg
    16501 tggtgcgcgg tgccgaagcc ggcacgacca gcctggagct gggcgacggc ggatcgatgg
    16561 ccgtgcgcgt gctgcccgac cactggtgga tggacgacat cccgcaggac gaggtcacct
    16621 tcgacctgct gtaccgcgag gtcttctcgt tctacgagct gatgtactcg ttcatggccg
    16681 aggaggtgtt cagcctcgcc gacaagttcc gcatcgacac ctactaccag atcacctggc
    16741 agatgtgcga tccgcgcaac cgcacgaaga cctactacat gccgcagacc cgcgacctga
    16801 ccggcccgca ggcccggttg ctgctcaagt acctgcgcgc acgacgcgcc gaggtggcgg
    16861 tcccgacgat cgagccgtcc ctcgcgcggt cggaccggcc gatcagcacc cgcgccgagc
    16921 tcatccgcgc gttgcggcac ggcgtcacca tcgagctcgc cgtgatgctg cagtacctgt
    16981 acgcggccta ctccgtgccc acctacggcg ccggtgagga actcgtccgc cgcggcgact
    17041 ggacgcccga gcagctgaca ctcatgtgcg gcgacggcgg cgagacccgc gacggcggcc
    17101 tgagggcgag cctgatggag gtcgcccgcg aggagatgat ccacttcctg gtggtcaaca
    17161 acgtcctgat ggccgccggc gaaccgttct acgtgcccga catcgacttc ggcacgctca
    17221 acgacacgct cccggtgccc ctggacttct cgctggaggc cctcaacctc ggcagcgtgc
    17281 agcgcttcat ccagatcgag cagccggaag gcctcaccgg cgccgtgcgg ctgggcgacc
    17341 tgccggctcc cacaccgtcc gaagaggact accactacgc ttctctgagc gaactgtacg
    17401 gcgacatcag ggaaggcctg caacgggtgc ccgacctgtt cctggtcgac aagggccgcg
    17461 gcggcggcga gcaccgcctg ttcctgcgcg agtcggtcaa cgcccggcac ccggactacg
    17521 tgctcgaggt cgacgacctg tccagcgcgc tgttcgcgat cgacttcgtg actgagcagg
    17581 gcgagggcca cgtgctgagc gaggaggaca ccggcgagga gtcgcactac gacaccttcg
    17641 tgcggatcgc cgacctgctc atgcgggaac gcctcaccgc caccgagaag ggccgcgcgc
    17701 agtggaaccc cgcctatccg gtggcgcgca acccgacgct gcacgaaggc cggcacgcca
    17761 aggaactcgt gaccgacccg gtcgccaggg agctggtggc gctgttcaac gggtcgtact
    17821 tcatggtgct gcagctgatg gtccagcact tcggcgaccc ggacgcgagc ctgcgccgct
    17881 cccggttcat gaacacggcc atcgacgtga tgaccggggt catgcgcccg ctggccgagc
    17941 tgctcgtggc cgtgccgtcc gggcggcacg gacgcacggc gggaccgtcg ttcgaactcg
    18001 acgagcagcc cgcgttcatc ccacggcccg acgtggcccg gcggtcgctc tcgctgcggt
    18061 tccgccggct tctggaggcg gcgcgcaagt gcgacctcgt gcccggcaaa gtggtcggca
    18121 acctcgagca cttcgccgag cagttcgccg caggaccggt cagctgaggt ggaccggcag
    18181 cgcgctgatc gccgtgatca acggcgtctg ccgccactcc gcctcgccgg gcttggcgtg
    18241 cgggaagcgg cggaagaacg ccgtgaggcc gacctggcac tggagctccg cgaggttcgc
    18301 gccgatgcac cggtgcacgc cgtgaccgaa ccccaggtgc tgaccgtcgc ccttgcgcag
    18361 gtcgaaccgc tccgggtcgg tgaacctgac cggatcccgg ttcgcctccc gcagcgcgca
    18421 caccacgatg tctccttgct gcacggtttt gccgtcgaac tcgaacggct cggtcgccat
    18481 ccggaacgac gtcatctgca gcggcgggtc gatccgcaac acctcgtgca cggccgacgg
    18541 cagcagactc cagtccgcca gcagcagttc cagctggtcc gggtggttca gcagcaggta
    18601 caacgccttg gcgagcaact gggtcgtcgc cgtctggccg ccgatcacca gggtgaacac
    18661 catcgaggcg agctcgtggt cgtcgaggcg ttcctcgtcg tcccgcatcg acaccagccg
    18721 ggacaccagg tcgtcacccg gattccggcg gcgctcgtcc acgagacccc tggtgtactc
    18781 ggcgaggcgg tgggtggcgt ccatcgcctc ttcgttgcgc gtcaacaggt ccagcacgaa
    18841 caggtcggac cagtaccgca cccgcgccgc gtccgcgggg tcgatgccga gcatcagccc
    18901 gagcaccttc gtcgccaacg gtccggcgaa gtcccgcacc agatcgggcc ggtcaccgaa
    18961 gtgctcgatg agctcggcgg cgatccgctc gacctgcggg cggtggtcgg cgatccggcg
    19021 cacggtgaac gtcggggtga ccaggcggcg cagccgggtg tgcgccggtg ggtcgttgtt
    19081 cagcatgtcg tgcgccatca ccgaggcgat cgactccggg aacgcggaga acggggcctt
    19141 gtcgcccatg cgcaacggat cgttggtgag ccgggaatcg gtcaggacgc tccgggtgcc
    19201 cgcgtagtcc gagacgagcc agaccttttt gccgtcgggg agctggatct gttccacgcg
    19261 cccgatgcta tgggcgccaa cggatgccgt gacactgcac gttcgcgcag gtggggtcgt
    19321 gagtggttgt gccgctcggg ccgcggtgtc caggtggttt caccgccggg ccacgctgcc
    19381 ccagcggttc cgccacgaac aacggcagcc caggtcgtac gcggtcgccg cggacgacgc
    19441 gaaactggcg ggcgcgaaac cggcgggcgc gaaaccggcg ggcgcgaaac cggcggcgcg
    19501 aaccggcggc gcgaaccggc gggcgcgaaa ccggcgggcg cgaaaccggc gggcgcgaaa
    19561 ccggcgggcg cggtgcgcat gacaccgtcg cagccgcacg actcgttgcc accccagcgc
    19621 tctcaccgcc cagaccacgg cgcccagctg gcttccaccc gccctgacaa cgatgtccac
    19681 tcacgatcct cacggcgcga tccgcgcgag gtccacccgc gactggatgg agagcttgcg
    19741 gtagatctgg cgcaggtgga atccgacggt gtgcggcgac acgaacatct cgctcgccac
    19801 ctgccggttg gtcagccccc gcgccaccag ccgcgcgacc ttcgcctcgg tgctggtgag
    19861 gctgccccat ccggtctccg gccggacctc gtggttccag tgccgcctgc gcacgccgag
    19921 cctgcgcagc ttgcgccgaa cgcgtgccga gtcccactcc gcgccgagct cgtcgtaggc
    19981 ggccatcgcc cggttcagct cggcgacggc gtggtcccgg tcggtgtcgc gcagcagcgt
    20041 gccggtgtcc tcgatcaccg acgccgccgc ccacgggtcg ccgtagcgct cctcgagtcc
    20101 ggacagagcg ctgacgtcgc tgtcgagcag cgccctgccg tgccgggcgg cggcgacgat
    20161 cgtgacgtag cgctggttct ccgcggcgat cttctcggcg gcgacgacca cgccctcggc
    20221 gatctccctg gcatcggcgg ccagcgcggt gcgcaccacc cacgccgtca tcgacgggtc
    20281 ctccagcaac agctggcggc gctggccggg atccgcgagc ggctcgcgga gttcctccat
    20341 cgccgcgtgc acgtcgcgcc gtgccgaggt gaccagtgcg gagagcacgc gcaccagcgg
    20401 cgtccacggt tgtgcgcgct ctgccggtgc gcactcctcc agcctgcgca ggccgtcgga
    20461 ggccgtggcc aggtcgccgc gccgcaacgc cgagatgacc agaaccgcgt gcagctgtgg
    20521 ttcgtacagc ggcatctccg cgcgttcgga ggcggtgagc ccggccgtcg cgtccgactc
    20581 ggcggcggcc aggtcgccct tggcgagcag gatcgtcgcg cggagtgcga gcggaaccgg
    20641 gctgagcacg ccgttgtgct cggtgtcgat ggccctgcgg gcggcgtcgg ccgcggcgag
    20701 cgcctcgtcg agcctgcgga ccctggtgag cagccacgct cttgtccaca gtggatcgga
    20761 ctgccacgcg cgggtgagcg ggccgcgcag ccgcaccgcc tcgtcgacgg cgttcatcgc
    20821 ggcgtcgagc ctgccctcgc gccagtacgc catcgcccgc acgttcagcg cggcggcacg
    20881 gacctcgtcg ctgcgctcgc ccggcacgtc cagcacccgg tccgccacgg cgacgacacg
    20941 gctttggtcg ttgtggcaca acgcgttgag cagcagcagc tccgggcatg gctcggtgtc
    21001 ggcactgagg gaattcgcgg gcgactgagc gtcggcgatg gtctcgttcg agacgtggaa
    21061 cgccgccgcg gtgtcgccgc gcagcatcag cgccgtggcg agccacgtcc gcaacggccg
    21121 ggtcaactcg ggacaggtgt gcacccgcag ctgctcctcg gcgagctcga cggcgtcgct
    21181 caggcacccg agccggacca gcgccgcggt ggccgtggtc gccagcgcgg cgtggtccgc
    21241 gctgtccggt ggtgcgatcc gcagtccccg cgtcgcgagc gccgacgcgg cctgcggcga
    21301 gccggcgagc atgcgctccg ccgccgcgcg gatcgtaccg atcgcctccg cgtcgccggg
    21361 catcgcgcag tgcaccaggt gcaccgcggc ggtctcgatc cggccctgcg gacggtcgag
    21421 cagcatggtg gcggcctgcc ggtgcagcat cgaacgcagc acctcgggca cggtgccgag
    21481 caccgcacgc cagaccggtt cgcgccggaa cacgaactcg tccgagtcgc tgccgatcag
    21541 cccggcggtg agagcctcct gcaacggccc gagcagctgg gccgggcgct cgcccagcat
    21601 ctcggcgagg tcctgcggcg cgaaactgct gccgagcacc gcggcgacct gcagcacctc
    21661 ctgcgcgcgc ggtgacagct cccgcagcct cgactgcatc agccggacga acggacgcgg
    21721 gagcggcgca ccgggatcgg gctcgaccgc cgaggagatc ccggtcggca tgggcccgga
    21781 cgccagtcgt gccacctggt cggtgaccgt gacgcagcct tcccgccgca cgtcgagcac
    21841 caggtcgacg atcgcctgcg gtgtgccgcc gacgctctcg cacagggcga gcacgtcgtc
    21901 gtccggtgtc gcgtcgagca ggtcacccgc gatgcccgcg acggcctcgc ccgtcagcgg
    21961 ctccagcggt ccgagccatt cggcgcggtg cttgcgcgcg agggtgcgca gcacgactcc
    22021 gttcggcgag tcggtgtggt cggcgtgcac cgcgaacaac cacaccaccg ggcaactgtc
    22081 caacttggac acgacggcgc cgagcgcgtg cagcagggcc agatcggtcc actgcacgtc
    22141 gtccacggcc accagcacgg gcccgcggcg caggtggccg gtcagctgcg cctcgaaccg
    22201 gccggcgagc gtgccgatcc ggtcgtcctc ctgcctgccg ttgcgggggt tgaccagggt
    22261 gaccgcccgc gcgaggcccg gctggtccgc cgcaccgttg acgaccgcga aaccgcgcct
    22321 ggccgcgcac gacatcagct cgagcagcag gcgggtcttg ccggtgccgg cgccggactc
    22381 gagcacgacg acgtgcgacc gttgctcttc cacgctgtcg cgcatcaact gctcgacgcg
    22441 gcctacctga gtcgctcgac cgtgcaacga ccacgtcagg ctcgtttccg gtatcgccga
    22501 gtccgtgagc tcttccaaaa tccgacgctt cac
//
