BGC0001340 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001340 (Paecilomyces fulvus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	52,546	High	byssochlamic acid/agnestadride A/agnestadride B/Triketide maleidride monomer type A	PKS:Type I

BGC0001340 - Region 1 - T1PKS

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Location: 1 - 52,546 nt. (total: 52,546 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 52,547
Label		BGC0001340

Tailoring functions

Ligases: synthase

bfpks1: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001340.3	0.96	PKS	byssochlamic acid, agnestadride A, agnestadride B, Triketide maleidride monomer type A	Byssochlamys fulva
BGC0001276.3	0.66	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0002191.2	0.66	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001273.3	0.65	PKS	asperlactone	Aspergillus ochraceus
BGC0002192.3	0.64	PKS	FR901512	fungal sp. No.14919
BGC0001254.3	0.63	PKS	ACT-Toxin II	Alternaria alternata
BGC0000107.3	0.63	PKS	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001164.3	0.63	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001268.4	0.60	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0000046.4	0.51	PKS	depudecin	Alternaria brassicicola

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001340.3	1.00	PKS	byssochlamic acid, agnestadride A, agnestadride B, Triketide maleidride monomer type A	Byssochlamys fulva
BGC0001276.3	0.66	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0002191.2	0.66	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001273.3	0.65	PKS	asperlactone	Aspergillus ochraceus
BGC0002192.3	0.64	PKS	FR901512	fungal sp. No.14919
BGC0001254.3	0.63	PKS	ACT-Toxin II	Alternaria alternata
BGC0000107.3	0.63	PKS	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001164.3	0.63	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001268.4	0.60	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0000046.4	0.51	PKS	depudecin	Alternaria brassicicola

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 6349 - 52546:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

bfpks1: pk

PKS_AT (621..942): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.0
Methoxymalonyl-CoA: 66.5
Malonyl-CoA: 57.3
Isobutyryl-CoA: 30.5
Benzoyl-CoA: 24.7
Propionyl-CoA: 19.6
trans-1,2-CPDA: 13.3
inactive: 13.1
fatty_acid: 13.0
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 5.2
Ethylmalonyl-CoA: 1.5
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

Link to PARAS substrate predictor