BGC0001340 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001340 (Paecilomyces fulvus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	52,546	byssochlamic acid/agnestadride A/agnestadride B/Triketide maleidride monomer type A	PKS:Type I	100%

BGC0001340 - Region 1 - T1PKS

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Location: 1 - 52,546 nt. (total: 52,546 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 52,547
Label		BGC0001340

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001340	0.89	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0000046	0.34	Polyketide	depudecin	Alternaria brassicicola
BGC0002227	0.25	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0001124	0.23	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002240	0.22	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0001749	0.22	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001583	0.21	Polyketide	emodin	Escovopsis weberi
BGC0000107	0.21	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0002729	0.21	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001606	0.21	Polyketide	gibepyrone-A	Fusarium fujikuroi IMI 58289

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001340	1.00	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0000046	0.67	Polyketide	depudecin	Alternaria brassicicola
BGC0002227	0.58	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0001124	0.56	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002240	0.55	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0001749	0.55	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001583	0.53	Polyketide	emodin	Escovopsis weberi
BGC0000107	0.53	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0002729	0.53	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001606	0.53	Polyketide	gibepyrone-A	Fusarium fujikuroi IMI 58289

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 6349 - 52546:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

bfpks1

PKS_AT (621..942): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.0
Methoxymalonyl-CoA: 66.5
Malonyl-CoA: 57.3
Isobutyryl-CoA: 30.5
Benzoyl-CoA: 24.7
Propionyl-CoA: 19.6
trans-1,2-CPDA: 13.3
inactive: 13.1
fatty_acid: 13.0
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 5.2
Ethylmalonyl-CoA: 1.5
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0