BGC0001341: valinomycin biosynthetic gene cluster from Rothia nasimurium
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Location: 260,465 - 281,286 nt. (total: 20,822 nt).
This entry is originally from NCBI GenBank LXWF01000040.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001341
Short description valinomycin biosynthetic gene cluster from Rothia nasimurium
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LXWF01000040.1
260465 - 281286
via
Compounds
  • valinomycin
Species Rothia nasimurium [taxonomy]
References
Chemical products information
valinomycin Evidence:
Copy SMILES
C54H90N6O18
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • A7979_04505
  • ORC16616.1
 260465 - 261097 (-) hypothetical protein
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    • A7979_04510
    • ORC16571.1
    		 261432 - 262238 (-) hypothetical protein
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      • A7979_04515
      • ORC16572.1
      		 262235 - 263107 (-) hypothetical protein
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        • A7979_04520
        • ORC16617.1
        		 263104 - 271074 (-) hypothetical protein
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          • A7979_04525
          • ORC16618.1
          		 271107 - 281186 (-) hypothetical protein
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            Biosynthesis information

            Biosynthetic modules

            Name
            Unk01
            Type
            nrps-type1
            Genes
            A7979_04520
            Substrates
            pyruvic acid (evidence: ATP-PPi exchange assay)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk02
            Type
            nrps-type1
            Genes
            A7979_04520
            Substrates
            valine (evidence: Structure-based inference)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk03
            Type
            nrps-type1
            Genes
            A7979_04525
            Substrates
            2-ketoisovaleric acid (evidence: ATP-PPi exchange assay)
            Integrated Monomers
            Domains
            adenylation
            Name
            Unk04
            Type
            nrps-type1
            Genes
            A7979_04525
            Substrates
            valine (evidence: Structure-based inference)
            Integrated Monomers
            Domains
            adenylation
            Annotation changelog

            Entry version: next

            Date
            Changes
            Submitters
            Reviewers
            2024-07-25
            MIBiG v4 annotathon
            • (ID: C62OJVVH7XOTOTFZSJT727YU)
            • (ID: 2U5WMR7MBJ4KI76XQF5437F7)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 3

            Date
            Changes
            Submitters
            Reviewers
            2022-09-15
            Added NRP substrate specificities
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 2

            Date
            Changes
            Submitters
            Reviewers
            2019-10-16
            Migrated from v1.4
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            2019-10-16
            Updated compound(s) information (NPAtlas curation)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2018-08-06
            Submitted
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            Detailed domain annotation
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