LOCUS       BGC0001345             19653 bp    DNA     linear   BCT 03-APR-2001
DEFINITION  Stigmatella aurantiaca myxochelin iron transport regulon, complete
            sequence.
ACCESSION   BGC0001345
VERSION     BGC0001345
KEYWORDS    .
SOURCE      Stigmatella aurantiaca Sg a15
  ORGANISM  Stigmatella aurantiaca Sg a15
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Stigmatella.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:22:38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19653
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..19653
                     /db_xref="taxon:675526"
                     /mol_type="genomic DNA"
                     /organism="Stigmatella aurantiaca Sg a15"
                     /strain="Sg a15"
     protocluster    1..19653
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[7162:11533]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7163..11533
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..19653
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2327:11533]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2328..11533
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
     cand_cluster    1..19653
                     /SMILES="NC(CCCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..19653
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001345"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19653
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            194..1174
                     /gene="mxcA"
     CDS             194..1174
                     /codon_start=1
                     /gene="mxcA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     101.2; E-value: 9.6e-31)"
                     /gene_kind="biosynthetic-additional"
                     /note="alcohol oxidoreductase"
                     /product="MxcA"
                     /protein_id="AAG31124.1"
                     /transl_table=11
                     /translation="MPHTLGNSGPAGTSLGLGLAALGRPGYITLGRAGDMGPDRSVQAL
                     EHRAHEVLDAAYHAGVRYFDAARSYGRAEDFLASWLASRGIKPGEVVVGSKWGYTYTAD
                     WNVDAERHEVKDHSVSTLRRQYAESRARLGAHLGLYQIHSATFESGVLDDALVLKELAR
                     LRENGLRVGLSLSGPQQAAVLRRALDIRVDGRPLFSCVQATWNVLERSVGSALAEAHAS
                     GWGVILKEVVANGRLGPRDEHPALHPFRALAAEQKTAPDVLAMAAALAQPWASIVLSGA
                     ATVAQLNSHLHALTLPYDEALDTCLRGMAEAPQVYWTTRSALPWN"
     gene            1285..2097
                     /gene="mxcB"
     CDS             1285..2097
                     /codon_start=1
                     /gene="mxcB"
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 308.5; E-value: 5.8e-94)"
                     /gene_kind="other"
                     /note="iron utilization protein"
                     /product="MxcB"
                     /protein_id="AAG31125.1"
                     /transl_table=11
                     /translation="MTQPERAPRRVPFAIKFRLLEVLRVAYVTPHMVRVTLGGKDLEGF
                     QTPAADDHVRLIFPAPGELKPVLPTMGPNGPVFPAGTPRPASRDYTPRRYDAAAGELDI
                     DFVVHGSGPGSTWATHAKPGDFVGVGGPRSSMIVPQDFAWYLLAGDATALPAIGRWLEE
                     LPTSAHAIVFIEVSDSSEEQQFNTRARVDLTWLHRNGAEPGNTNQLEKAIRTLEFPPGD
                     HFIWLAGEANTLRPIREHVYNERGTPKKWVSATGYWKRNTVDHHEPHD"
     gene            2328..3101
                     /gene="mxcC"
     CDS             2328..3101
                     /NRPS_PKS="Domain: PKS_KR (6-162). E-value: 1.1e-14. Score:
                     46.6. Matches aSDomain: nrpspksdomains_mxcC_PKS_KR.1"
                     /codon_start=1
                     /gene="mxcC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     242.7; E-value: 7e-74)"
                     /gene_kind="biosynthetic"
                     /note="2,3-dihydro-2,3-dihydroxy benzoic acid
                     dehydrogenase"
                     /product="MxcC"
                     /protein_id="AAG31126.1"
                     /sec_met_domain="EntA (E-value: 9e-118, bitscore: 382.1,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.2e-37, bitscore:
                     118.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTTSKVALVTGAAQGIGAAVVRALADNALVAALDTQEEKLSALI
                     ADLGQGRGRVSAFRADVRDSSAVETVIDRVERELGPIGILVNVAGVLRAGPAIALSDED
                     WETTFAVNTQGVFHVSRAVARRMVPRKTGVIVTVASNASGTPRMQMAAYAASKAASAMF
                     TKCLGLELAQHNIRCNVVSPGSTDTAMQRALWTDERGGEATIHGSLETFRLGIPLRRLA
                     TPADIADAVVFLTSDRARHITMHDLCVDGGATLGV"
     aSDomain        2346..2813
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcC_PKS_KR.1"
                     /evalue="1.10E-14"
                     /label="mxcC_PKS_KR.1"
                     /locus_tag="mxcC"
                     /protein_end="162"
                     /protein_start="6"
                     /score="46.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGAAQGIGAAVVRALADNALVAALDTQEEKLSALIADLGQG
                     RGRVSAFRADVRDSSAVETVIDRVERELGPIGILVNVAGVLRAGPAIALSDEDWETTFA
                     VNTQGVFHVSRAVARRMVPRKTGVIVTVASNASGTPRMQMAAYAASKAASAM"
     CDS_motif       2352..2411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcC_0001"
                     /evalue="4.30E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="mxcC"
                     /protein_end="28"
                     /protein_start="8"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LVTGAAQGIGAAVVRALADN"
     gene            3234..4460
                     /gene="mxcD"
     CDS             3234..4460
                     /codon_start=1
                     /gene="mxcD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 395.4; E-value:
                     6.8e-120)"
                     /gene_kind="biosynthetic"
                     /note="isochorismate synthase"
                     /product="MxcD"
                     /protein_id="AAG31127.1"
                     /sec_met_domain="EntC (E-value: 1.5e-154, bitscore: 504.7,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERPMSPQKLAAQLLESYEAGSSFFFATPKRTMLARGTFATVPH
                     IGGADALQRLPERVAAVLNNAREAAHDIPVAVGAVPFDGSIPAQMVVPMTLQRAGPLVF
                     DTDVPVHQPLAARYTVQPVPEPAAYLDGVTQALKLMQTGSLRKVVLSRSLHLSATTPID
                     LPQLLRNLAQRNPSGYTFAVDLPPGATQAAGGLRRTLIGASPELLVSRSGLQVLANPLA
                     GSAARSANPIEDQERAATLLKSSKDLHEHAVVIEAVVEAMRPYCKKLDVPSGPSLVSTQ
                     TMWHLSSRICGELADPSITSLALAVALHPTPAVCGYPTELAHEAITTIEPFQRGFYTGT
                     VGWCDASGDGQWAVTIRCAEADERTLRLFAGAGIVVGSKPESELAETEAKFRTMLQAMG
                     LGQNAEVQS"
     gene            4457..6088
                     /gene="mxcE"
     CDS             4457..6088
                     /NRPS_PKS="Domain: AMP-binding (42-446). E-value: 3.7e-88.
                     Score: 287.7. Matches aSDomain:
                     nrpspksdomains_mxcE_AMP-binding.1"
                     /codon_start=1
                     /gene="mxcE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     497.4; E-value: 6.3e-151)"
                     /gene_kind="biosynthetic-additional"
                     /note="2,3-DHBA-AMP ligase"
                     /product="MxcE"
                     /protein_id="AAG31128.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-95, bitscore:
                     310.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPSPQREPSLLPGCTAWPEEYAAHYRKAGYWRGETFGQMLRER
                     AQRHGDRTAVVAGTQRWSYRELDERTDRLVAGFHALGIKPRDRVVVQLPNTAEFFEVIF
                     ALFRLGALPVFALPAHRSAEINYFCEFTEAVAYVIPDKHSGFDYRTLAEKVRSAVPGLR
                     HVVVVGEAGPFTSLSQLYASPVDLPGPIPSDVAFFQLSGGSTGVPKLIPRTHDDYIYSL
                     RGSVEICQLDETTVYLCALPAAHNFPLSSPGVLGTLYAGGTAVMALHPSPDQAFPLIER
                     ERITFTALVPPLAMIWMDAAKARRHDLSSLKVLQVGGARLSTEAAQRVRPTLGCALQQV
                     YGMAEGLVNYTRLDDPDELVIATQGRPISPDDEIRIIDEDGRDVAPGETGQLLTRGPYT
                     IRGYYNAEAHNARAFTSDGFYCTGDLVRVTPEGYLVVEGRAKDQINRGGDKIAAEEVEN
                     HLLAHPSVHDAAVISIPDPFLGERTCAFVIPREAPPTAATLTSFLRERGLAAYKIPDRV
                     EFVATFPQTGVGKVSKKALRETLAHR"
     aSDomain        4583..5794
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcE_AMP-binding.1"
                     /evalue="3.70E-88"
                     /label="mxcE_AMP-binding.1"
                     /locus_tag="mxcE"
                     /protein_end="446"
                     /protein_start="42"
                     /score="287.7"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="RERAQRHGDRTAVVAGTQRWSYRELDERTDRLVAGFHALGIKPRD
                     RVVVQLPNTAEFFEVIFALFRLGALPVFALPAHRSAEINYFCEFTEAVAYVIPDKHSGF
                     DYRTLAEKVRSAVPGLRHVVVVGEAGPFTSLSQLYASPVDLPGPIPSDVAFFQLSGGST
                     GVPKLIPRTHDDYIYSLRGSVEICQLDETTVYLCALPAAHNFPLSSPGVLGTLYAGGTA
                     VMALHPSPDQAFPLIERERITFTALVPPLAMIWMDAAKARRHDLSSLKVLQVGGARLST
                     EAAQRVRPTLGCALQQVYGMAEGLVNYTRLDDPDELVIATQGRPISPDDEIRIIDEDGR
                     DVAPGETGQLLTRGPYTIRGYYNAEAHNARAFTSDGFYCTGDLVRVTPEGYLVVEGRAK
                     DQINR"
     CDS_motif       5612..5698
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcE_0001"
                     /evalue="7.50E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="mxcE"
                     /protein_end="414"
                     /protein_start="385"
                     /score="12.0"
                     /tool="antismash"
                     /translation="PGETGQLLTRGPYTIRGYYNAEAHNARAF"
     gene            6166..7101
                     /gene="mxcF"
     CDS             6166..7101
                     /NRPS_PKS="Domain: PP-binding (224-285). E-value: 3.1e-11.
                     Score: 35.6. Matches aSDomain:
                     nrpspksdomains_mxcF_PP-binding.1"
                     /codon_start=1
                     /gene="mxcF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 394.9; E-value:
                     2.2e-120)"
                     /gene_kind="biosynthetic-additional"
                     /note="isochorismatase"
                     /product="MxcF"
                     /protein_id="AAG31129.1"
                     /sec_met_domain="PP-binding (E-value: 6.6e-12, bitscore:
                     35.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPAIAPYRMPSAADLPTNKVSWTPDPQRAVLLIHDMQRYFVDA
                     FTSGASPVTELVANIRQLRQHCISVGIPVVYSAQPGGQTPEQRGLLLDFWGAGINGGPH
                     QKQIIDALTPAEGDIVLTKWRYSAFNRTQLMDILRQSKRNQLIVCGIYAHIGCLQTASE
                     AFMNEVQPFFVADGVADFSWENHQMALNYAARLCAVTTTTQQLIDQLRPQATRGGVPLS
                     RQQVRADVIEMLQQDAALGDDENLLECGLDSIRLMTLVERWRNAGTEVTFVELAERPTL
                     GDWYSMLTSIAQPPPVEVAAALQRGVRPTA"
     aSDomain        6838..7020
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcF_PP-binding.1"
                     /evalue="3.10E-11"
                     /label="mxcF_PP-binding.1"
                     /locus_tag="mxcF"
                     /protein_end="285"
                     /protein_start="224"
                     /score="35.6"
                     /tool="antismash"
                     /translation="QVRADVIEMLQQDAALGDDENLLECGLDSIRLMTLVERWRNAGTE
                     VTFVELAERPTLGDWY"
     gene            7163..11533
                     /gene="mxcG"
     CDS             7163..11533
                     /NRPS_PKS="Domain: Condensation_Starter (6-299). E-value:
                     1.4e-106. Score: 348.1. Matches aSDomain:
                     nrpspksdomains_mxcG_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (466-870). E-value: 2.6e-97.
                     Score: 317.8. Matches aSDomain:
                     nrpspksdomains_mxcG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (976-1045). E-value: 2.2e-21. Score:
                     67.7. Matches aSDomain: nrpspksdomains_mxcG_PCP.1"
                     /NRPS_PKS="Domain: TD (1094-1332). E-value: 2.2e-82. Score:
                     267.8. Matches aSDomain: nrpspksdomains_mxcG_TD.1"
                     /codon_start=1
                     /gene="mxcG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 90.2;
                     E-value: 2.7e-27)"
                     /gene_kind="biosynthetic"
                     /note="peptide synthetase; contains adenylation,
                     condensation, peptidyl carrier protein, and reductase
                     domains"
                     /product="MxcG"
                     /protein_id="AAG31130.1"
                     /sec_met_domain="Condensation (E-value: 2.4e-45, bitscore:
                     144.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.3e-106, bitscore:
                     343.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-15, bitscore:
                     47.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-07,
                     bitscore: 20.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.9e-67, bitscore:
                     216.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDSQETRRPLSAAQHGIWLGQQFDLKSPVYNAGECIEICGPVDP
                     ALFEAAVRQAVREAEALHVRFVASEEGPQQLLGLQTDWVLHTADLSESPDPWAAVQAWM
                     KADLAQTVDLSRGPLFTEALFKAAPDRFFWYQRIHHIAMDGFGFSLLARRVAEVYTALA
                     AGRPITGGFGSFQAVLDEDVAYRNGPQHELDRTFWTERFADRPTPVSLASPAPMSPSFV
                     RQTRFLPAQSMERLQAVSRPAGLNWPDLVLAATAVYLHRLTDATEVVLGLPVMTRLGSA
                     ALRVPCMAMNIVPLRVPVSPEASLLDLARGIAAEVRAMRPHLRYRYEQLRRDLKLVGGQ
                     RRLFGPVVNIMPFDYALRFAGMPTIAHNISAGPVEDLSIGLYARADGKGLRVDFDANPA
                     CYEAKALESHPSAFLELLEALTAAPDQAVGRDSGSLSSSSSKAPSLASVLDGGPLPVAA
                     QPVLQLIAERALEQPDAIAVEHGQHQMSYRELLQSAQALSAQLISAGVQPNTAVAVMLP
                     RGLDAIVASLGVLFSGAGYLPLDPYGPSSRTAAILEDAKPALIIQRSTPDADPLSRGNL
                     VIRQNEQAPAAAPSSRTLPQTSGEHLAYVIYTSGSTGQPNGVQISHEALAHFVAGATHR
                     YGVRRDDRVLQFAPLHFDASVEEIFLTLCAGAKLVLRTEEMLQSVSRLLDACAEHGITV
                     LDLPTAFWHELAYSVSTGAARLPSSIRLVIIGGEAALPERVARWRSAVSPEVLLLNTYG
                     PTEATVVATTATLSGPAPAGTPEEEIPIGRPLPGVRAALIDAQGKLAAPGAEGELYLLG
                     GGLARGYLGRPELNTARFTTLGMLSDRPRAYRTGDKARVREDGQLVFVGRVDDEFKISG
                     HRIDPTEIETVLLSHSGVREAAVVGQILPGGTRRLCAHIVAEMPVPATAELRRHLLSEL
                     PAAMVPSAFVFAEKLPRTSTGKLDRNALRLVQPPEEATPTATTTPFERMVLQVWEQVLG
                     LSRITAQDDFFELGGQSLQTIQVANRLSVALGRDVPVATVFRYPTAAGLAQALEHGEQH
                     SVEGEGISKAMLADAELPEEIVPRLPTPGAEAPLAPSPGPAAPLRQVLLTGATGFVGAH
                     LLDQLLRQTQAKVVCLVRARDEAHAMERLREAMTSQRLSTASLSERVLALPADLGQPWL
                     GLSSARFHGLAAECDMILHNAAVVSVVREYGSLQATNVRGTRELLRLAASVRPKPLHYV
                     STLAVAPQANLSPEVPEAFVPAHPGLRDGYQQSKWAAERLVEQASERGLPVTVYRLGRV
                     SGALDSGIVNPQDLVWRILLAGIPAGALPQLDVGEVWTPVDYVARALVRLSLVPRPGTV
                     FNLTPAPEVRLSEVFGWVQDYGYPVALCPVPEWRTRVAQSTGSAENSTTLAFFDLRAGA
                     AEPTFGLGTIRSERVLQALSDTGISCPRTDRPLLHRYLDYCVGQGLLQRPPEHR"
     aSDomain        7181..8059
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcG_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.40E-106"
                     /label="mxcG_Condensation_Starter.1"
                     /locus_tag="mxcG"
                     /protein_end="299"
                     /protein_start="6"
                     /score="348.1"
                     /tool="antismash"
                     /translation="TRRPLSAAQHGIWLGQQFDLKSPVYNAGECIEICGPVDPALFEAA
                     VRQAVREAEALHVRFVASEEGPQQLLGLQTDWVLHTADLSESPDPWAAVQAWMKADLAQ
                     TVDLSRGPLFTEALFKAAPDRFFWYQRIHHIAMDGFGFSLLARRVAEVYTALAAGRPIT
                     GGFGSFQAVLDEDVAYRNGPQHELDRTFWTERFADRPTPVSLASPAPMSPSFVRQTRFL
                     PAQSMERLQAVSRPAGLNWPDLVLAATAVYLHRLTDATEVVLGLPVMTRLGSAALRVPC
                     MAMNIVPLRVPV"
     aSModule        7181..11158
                     /complete
                     /domains="nrpspksdomains_mxcG_Condensation_Starter.1"
                     /domains="nrpspksdomains_mxcG_AMP-binding.1"
                     /domains="nrpspksdomains_mxcG_PCP.1"
                     /domains="nrpspksdomains_mxcG_TD.1"
                     /final_module
                     /locus_tags="mxcG"
                     /monomer_pairings="Lys -> Lys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7190..7228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0001"
                     /evalue="8.50E-04"
                     /label="C1_starter_004-017"
                     /locus_tag="mxcG"
                     /protein_end="22"
                     /protein_start="9"
                     /score="12.1"
                     /tool="antismash"
                     /translation="PLSAAQHGIWLGQ"
     CDS_motif       7247..7363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0002"
                     /evalue="7.30E-21"
                     /label="C2_starter_024-063"
                     /locus_tag="mxcG"
                     /protein_end="67"
                     /protein_start="28"
                     /score="66.7"
                     /tool="antismash"
                     /translation="PVYNAGECIEICGPVDPALFEAAVRQAVREAEALHVRFV"
     CDS_motif       7574..7639
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0003"
                     /evalue="2.50E-12"
                     /label="C3_starter_134-155"
                     /locus_tag="mxcG"
                     /protein_end="159"
                     /protein_start="137"
                     /score="39.4"
                     /tool="antismash"
                     /translation="IHHIAMDGFGFSLLARRVAEVY"
     CDS_motif       7961..8050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0004"
                     /evalue="2.70E-14"
                     /label="C5_starter_265-294"
                     /locus_tag="mxcG"
                     /protein_end="296"
                     /protein_start="266"
                     /score="45.3"
                     /tool="antismash"
                     /translation="EVVLGLPVMTRLGSAALRVPCMAMNIVPLR"
     CDS_motif       8099..8212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0005"
                     /evalue="4.80E-18"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="mxcG"
                     /protein_end="350"
                     /protein_start="312"
                     /score="57.6"
                     /tool="antismash"
                     /translation="AAEVRAMRPHLRYRYEQLRRDLKLVGGQRRLFGPVVNI"
     aSDomain        8561..9772
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcG_AMP-binding.1"
                     /evalue="2.60E-97"
                     /label="mxcG_AMP-binding.1"
                     /locus_tag="mxcG"
                     /protein_end="870"
                     /protein_start="466"
                     /score="317.8"
                     /specificity="substrate consensus: Lys"
                     /tool="antismash"
                     /translation="ERALEQPDAIAVEHGQHQMSYRELLQSAQALSAQLISAGVQPNTA
                     VAVMLPRGLDAIVASLGVLFSGAGYLPLDPYGPSSRTAAILEDAKPALIIQRSTPDADP
                     LSRGNLVIRQNEQAPAAAPSSRTLPQTSGEHLAYVIYTSGSTGQPNGVQISHEALAHFV
                     AGATHRYGVRRDDRVLQFAPLHFDASVEEIFLTLCAGAKLVLRTEEMLQSVSRLLDACA
                     EHGITVLDLPTAFWHELAYSVSTGAARLPSSIRLVIIGGEAALPERVARWRSAVSPEVL
                     LLNTYGPTEATVVATTATLSGPAPAGTPEEEIPIGRPLPGVRAALIDAQGKLAAPGAEG
                     ELYLLGGGLARGYLGRPELNTARFTTLGMLSDRPRAYRTGDKARVREDGQLVFVGRVDD
                     EFKIS"
     CDS_motif       8741..8782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0006"
                     /evalue="9.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="mxcG"
                     /protein_end="540"
                     /protein_start="526"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGVLFSGAGYLPLD"
     CDS_motif       8969..9028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0007"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="mxcG"
                     /protein_end="622"
                     /protein_start="602"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPNGVQISH"
     CDS_motif       9566..9652
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0008"
                     /evalue="7.50E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="mxcG"
                     /protein_end="830"
                     /protein_start="801"
                     /score="37.5"
                     /tool="antismash"
                     /translation="PGAEGELYLLGGGLARGYLGRPELNTARF"
     CDS_motif       9737..9802
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0009"
                     /evalue="9.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="mxcG"
                     /protein_end="880"
                     /protein_start="858"
                     /score="24.4"
                     /tool="antismash"
                     /translation="FVGRVDDEFKISGHRIDPTEIE"
     aSDomain        10091..10297
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcG_PCP.1"
                     /evalue="2.20E-21"
                     /label="mxcG_PCP.1"
                     /locus_tag="mxcG"
                     /protein_end="1045"
                     /protein_start="976"
                     /score="67.7"
                     /tool="antismash"
                     /translation="ERMVLQVWEQVLGLSRITAQDDFFELGGQSLQTIQVANRLSVALG
                     RDVPVATVFRYPTAAGLAQALEHG"
     aSDomain        10445..11158
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcG_TD.1"
                     /evalue="2.20E-82"
                     /label="mxcG_TD.1"
                     /locus_tag="mxcG"
                     /protein_end="1332"
                     /protein_start="1094"
                     /score="267.8"
                     /tool="antismash"
                     /translation="VLLTGATGFVGAHLLDQLLRQTQAKVVCLVRARDEAHAMERLREA
                     MTSQRLSTASLSERVLALPADLGQPWLGLSSARFHGLAAECDMILHNAAVVSVVREYGS
                     LQATNVRGTRELLRLAASVRPKPLHYVSTLAVAPQANLSPEVPEAFVPAHPGLRDGYQQ
                     SKWAAERLVEQASERGLPVTVYRLGRVSGALDSGIVNPQDLVWRILLAGIPAGALPQLD
                     VGEVWTPVDYVARALV"
     CDS_motif       10448..10537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mxcG_0010"
                     /evalue="1.70E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="mxcG"
                     /protein_end="1125"
                     /protein_start="1095"
                     /score="7.8"
                     /tool="antismash"
                     /translation="LLTGATGFVGAHLLDQLLRQTQAKVVCLVR"
     gene            11580..13013
                     /gene="aroAA5"
     CDS             11580..13013
                     /codon_start=1
                     /gene="aroAA5"
                     /note="DAHP synthase"
                     /product="AroAA5"
                     /protein_id="AAG31131.1"
                     /transl_table=11
                     /translation="MLKQNWTPGSWRAKPVKHMPDDYPDARELARVEEELSRLPPLVFA
                     EETRRLTAALGQVAEGQAFLLQGGDCAESFKEFTTDNVRDSLRLILQMAVVLTFSGGRP
                     VVKVGRIAGQFAKPRSGASETIEGVTLPAYRGDIINGMEFEPGDRMPDPKRLLKAYHQS
                     SDTLGLLRLFSQGGYADLCNMHRWTFDFVADSVQGGQYRKLADKILESLRFMSALHVSP
                     GQQMPLNRVDMFTSHEALLLNFEEAMTRADPISGDWYDTSAHMLWIGERTRQLDGGHVE
                     FMRGIQNPIGLKCGPTMEPEDLLRLMDILNPDAIPGKLTLIGRFGADKIAERLPRLMAA
                     TKRDGRPVVWSTDPMHGNTLKARNGYKTRPFDRILSEVKTFVQVATSEGVHPGGLHLEM
                     TGQNVTECLGGAQAVTEDDLSSRYHTHCDPRLNANQALQLAFLVADKLQSLRVSEAWAA
                     VSTDSLTEMSGKEYHAAPK"
     stem_loop       13010..13032
                     /gene="mxcH"
     gene            13010..15619
                     /gene="mxcH"
     CDS             13010..15619
                     /codon_start=1
                     /gene="mxcH"
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 65.4; E-value: 8.6e-20)"
                     /gene_kind="transport"
                     /note="membrane receptor"
                     /product="MxcH"
                     /protein_id="AAG31132.1"
                     /transl_table=11
                     /translation="MKMRSIFIVSSPFGTPTRERALARLCRTALLAALLTSRLAQAQEQ
                     SPERATPQAPSGSAPAPQPSEAPPAAPVVEMPKLLEIVEAIYPAQAKQDRLEAKVALRL
                     TLDAQGVVKTAEVLGPVGHGFDEAAQEAALRFRFEPAKRNGTTVPARVVYTYEFRLPPP
                     PTPPSAQPSGQAAASESSDSSFGETIEVSAGGESVAQRRRQSAEAVQVLEVGTLQREAV
                     DLGEALARTEGVSVRRSGGLGSTSRFSIAGLTDEQIRFFIDGVPLELAGYGAGLANVPV
                     NLVQRVETYQGVVPIRFGADALGGAVHLETDQNFQGLGASASYEFGSFDTHRLTASIRQ
                     LHEPTGFLLRASGFFDTTRNDYLVDVEVEAADGSGRPVRARVHRFHDGYRAGGAGIEAG
                     FVDQSWARRLLLRVFTGTYDKDLQNDIEMSAPYGEVEYGETSGGSTLRFEQIYSNGLSV
                     DAIAGYTYRRNHLTDLSQCVYDWYGRCILVLPQPGVLEGRPIERTIGQHTGFARLNFGW
                     NVSPSQKFRLSLAPTFVDRAGEDRQLQEAQQLDPLDGERNLFSLVAGLEYEIDAFEERL
                     ENILFVKDYLQRAYGEKPLDGGEFAITKRNLHQVGVGDSARLRFAPGLYAKASYEWATR
                     MPRPDEFFGDGLLVVENLKLQPETSHNLNLGLTYEAPSTPAGDFRANVTGFGRLADQLI
                     LLVPQPSYFVYENVFAARSLGVSGTAGWISPGRYVSLDGNATWQDFRNTSSEGVYGAFV
                     DKRIPNRPYLFANGSARFELSNLMNPRDELALTWNLRYIHKFFRAWEGFGKVDTKDVIA
                     SQWVHSLSLTYVTRSDSATLTWSADAQNLTDAKAFDFYGVQRPGRSLFATLTVDFET"
     misc_feature    15374..15376
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15650..16894
                     /gene="mxcI"
     CDS             15650..16894
                     /codon_start=1
                     /gene="mxcI"
                     /note="function unknown"
                     /product="MxcI"
                     /protein_id="AAG31133.1"
                     /transl_table=11
                     /translation="MNLTKTLRPVRWLAAVLALPLLTACGDDEEVTPPPPPSTASQYAV
                     VTQVTSDSGSSASYVVVTDSVDHTETLSLTNAIEVTGRALVFGPPKKDHFFVSSGKSVI
                     RYNLTESGTPEKGATVLFSDLPEDITEYQHQFRFISETKAYFFDGSTTQVIVWNPSAMT
                     VTRRVPFGDVKPANTVLSFSSQPLDVANLVIMPLGWRPSTGTTITKQAGVLVVDPNTDT
                     LQFVKKEFKEGEGCGYVRDGVVGKDGKVYLSTEAYGSASYRVHRDDPATLKPCLLRFDP
                     QTKTFDDFFVDLTTLSNGAPAGSVLQGPGGKTYLRVLDEASFTGTITKETHPRLLASAV
                     AWKWWEIKLDTLTATPVSTLPAAMGSTFLFPANDRVLFTNFTSNSQTELRELTDASGKV
                     ATVTPGRTFSFLQVR"
     gene            17124..18347
                     /gene="mxcK"
     CDS             17124..18347
                     /codon_start=1
                     /gene="mxcK"
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 301.1; E-value: 1.5e-91)"
                     /gene_kind="transport"
                     /note="efflux pump"
                     /product="MxcK"
                     /protein_id="AAG31134.1"
                     /transl_table=11
                     /translation="MSASSAPGSERRLLWLLAAVQFSHLMDFMIVMPLGPEFMRLFGIS
                     AAQFGVLVSAYTLASAAMGLLGVLWLDRFDRKRTLLALYGGFIVATLMCGAAQSHIALL
                     VARTLAGACAGLMGAVIMAIIGDLVPPERRGNAIGTVMASLGLSAVVGVPLGLGLANLW
                     GWKMPFWAIGGFASVMWLGLWKVLPPLRQHLSASREQVRGDSLISLWTPSLALGWLLTF
                     SVVISSFLLIPYLSPYMVGNLGLETAQLPWVYLGGGAATLLCTRWIGRMTDRHGPVRVL
                     ASLLMGTMVPHLLFTHLPPSPFPVVALIFALFMSLTSSRVIPTIALISARVPPSVRGRY
                     LAVNMAASDGASGIAAWMSGLMISTATGGALEGFGQTGWIAVGVSAFALCVLWTLGRST
                     VRLSAAPT"
     gene            18391..19653
                     /gene="mxcL"
     CDS             18391..19653
                     /NRPS_PKS="Domain: Aminotran_3 (58-343). E-value: 1.7e-47.
                     Score: 153.9. Matches aSDomain:
                     nrpspksdomains_mxcL_Aminotran_3.1"
                     /codon_start=1
                     /gene="mxcL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 231.5;
                     E-value: 2.7e-70)"
                     /gene_kind="biosynthetic-additional"
                     /note="aldehyde amino-transferase"
                     /product="MxcL"
                     /protein_id="AAG31135.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.5e-46, bitscore:
                     147.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTHSKRHPSLPRPIQGEMKLENSNRLLAEAKRLIPGVTLSMMKR
                     PEHFAPDAFPVYLARGQGALVEDVDGQQYIDFIGGLGANMLGHNHPAVVESIRKHLDEG
                     LIHSLPTPVELSASQTLIEMIPGAEMARFFKTGADATSAAMRLARIITGKERIITVGYN
                     GWHDHFMVGTPGVPAVMSQYTIRMPLFTPQDETALLACIGENAKQLAAVLISIPFNRCL
                     SREFMHQLRAACTAHEVLMVQDEVITGFRLARGGAQEFFDVKADFVCLSKALAAGMPLS
                     AVAGPAKHLSKLGAMEVQVSTTFGGEMLSLAVCEATLKEYRKGGYIEQLAALGSRLRTG
                     INAKAEKAGSPLRVLGYDSIPFLLFDKNPTEHAKRMQPFQAGMARRGILLRRDVNFISA
                     VHTQEQIDYTIEMAGEVLQSL"
     aSDomain        18565..19419
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mxcL_Aminotran_3.1"
                     /evalue="1.70E-47"
                     /label="mxcL_Aminotran_3.1"
                     /locus_tag="mxcL"
                     /protein_end="343"
                     /protein_start="58"
                     /score="153.9"
                     /tool="antismash"
                     /translation="ARGQGALVEDVDGQQYIDFIGGLGANMLGHNHPAVVESIRKHLDE
                     GLIHSLPTPVELSASQTLIEMIPGAEMARFFKTGADATSAAMRLARIITGKERIITVGY
                     NGWHDHFMVGTPGVPAVMSQYTIRMPLFTPQDETALLACIGENAKQLAAVLISIPFNRC
                     LSREFMHQLRAACTAHEVLMVQDEVITGFRLARGGAQEFFDVKADFVCLSKALAAGMPL
                     SAVAGPAKHLSKLGAMEVQVSTTFGGEMLSLAVCEATLKEYRKGGYIEQLAALGSRLRT
                     GINA"
ORIGIN
        1 ggatacctcg gggattttct cacccgctcc cgcggccagc gcgaccagtg gaacaacgag
       61 taagcccacc catcccctct tcgagcgtcg gtccatgccc accggtacgc gcgacgccac
      121 cgaaagttac gggatggaga atctatggca ccctccctcc tccctccgcg acagagagag
      181 ggtggagaac cccatgcctc acactctcgg taactccggg cccgccggca cctccctggg
      241 gctcgggctg gcggccttgg ggcgcccggg ctacatcacc ctcggccgcg cgggggacat
      301 ggggcccgat cggtccgtgc aagccctgga gcaccgcgcc catgaggtcc tcgatgcggc
      361 gtaccacgct ggcgtgcgct acttcgacgc ggcgcgctcc tatggccggg ccgaggactt
      421 cctggcctcg tggctggcct cacgcggaat caagccgggc gaagtcgtcg tgggttccaa
      481 atggggctac acgtacactg cggactggaa cgtggacgcc gagcgccacg aggtgaagga
      541 ccactccgtg tccaccctgc gccgccagta cgccgagagc cgcgctcggc tgggagccca
      601 cctgggcctc taccagattc actccgccac ctttgagagt ggcgtcctgg acgatgcact
      661 cgtgctgaaa gaactcgccc ggctgcgcga aaacggcctg cgcgtggggc tctcgctcag
      721 tggtccccaa caagccgcgg tgctgcggcg cgcgctggac atccgcgtgg acggacgacc
      781 tttgttttcc tgtgtgcagg ccacctggaa cgtgctcgaa cgctccgtgg gctccgccct
      841 cgccgaagcc catgcctccg gatggggcgt catcctcaaa gaggttgtcg ccaatgggcg
      901 gctcggccct cgggacgagc accccgcgct gcaccccttt cgcgccttgg ccgcggagca
      961 gaagaccgcc ccggatgtgc tcgccatggc tgccgccttg gcccagccct gggcgagcat
     1021 agtgctcagt ggcgcggcca cagtggccca actgaacagt cacctgcatg ccctgaccct
     1081 gccttacgac gaggccctcg acacctgcct gcgcggcatg gccgaagcac ctcaggtcta
     1141 ctggactaca cgaagcgcct tgccttggaa ctgagccgaa acaggccctg cccaggggac
     1201 agttgcgttc tctttctatc cgtgattatg ataatgcgat tcaatatcaa ttaggccgcc
     1261 ctctccggcc catgagaatc catgatgacc cagccagagc gggcgccccg ccgcgtgccc
     1321 ttcgcgatca agtttcggct cctcgaagtc ctccgtgtgg cttacgtcac cccccacatg
     1381 gtgcgggtca ccctcggagg aaaggacctc gaaggcttcc agacccccgc agcggatgac
     1441 catgtgaggc tgatctttcc agcccctggc gagctcaaac ccgtccttcc caccatgggc
     1501 cccaacgggc cggtctttcc agcgggcacg cctcgccctg cctcgcgcga ctacacgccc
     1561 cggcgctatg acgccgccgc aggcgaactg gacatcgatt tcgtggtgca tggctctggg
     1621 cccgggtcga cctgggccac ccatgccaag ccaggagact tcgtcggcgt gggaggccct
     1681 cgcagttcga tgattgtccc ccaggacttc gcctggtacc tgctcgcggg cgatgccacc
     1741 gcgctgccag ccatcggccg ctggctggag gaacttccca ccagcgccca cgcgattgtg
     1801 ttcatcgagg tcagcgactc ctccgaagaa caacaattca acacccgtgc cagggtagac
     1861 ctgacctggt tgcatcggaa tggcgcggaa cctggaaaca cgaatcaact ggaaaaagcc
     1921 atccgcactc tggagtttcc tcccggagac cacttcatct ggctggcggg cgaagccaac
     1981 accctgcggc ccatccgcga gcacgtttac aacgagcgcg gcacgcccaa gaaatgggtc
     2041 agtgccacgg gatactggaa acgaaacacc gttgaccacc atgagcctca cgactgagtg
     2101 tcccaacgga ggttcgccca cggcagggtg agcatttcac tcacgtctca cccgccgtcc
     2161 cccccctcac cgggcaggac gcttgacatg aagggtcagg acatgagacc ccccgacact
     2221 gaatatgaga accattctca taaacgtgtc cgcattgaga gcggcaggtt tccggccatt
     2281 cgagggcagc catcgggctt tccctctcca caagggcaag tagacgcatg ggaacgacct
     2341 ccaaggtggc cctggtcacg ggcgcggcgc agggcatcgg tgcggccgtc gtgcgcgcac
     2401 tggcggacaa cgcattggtc gccgcgctcg acacccagga agaaaagctc tccgcgttga
     2461 tcgcggactt gggacaaggc cgtggccgtg tctccgcatt ccgggcggac gtgcgtgaca
     2521 gctccgcggt cgaaaccgtg atcgatcggg tcgagcgcga gttgggacct atcggtatcc
     2581 tggtcaacgt ggccggagtg cttcgggcgg gcccggccat cgcgctcagc gacgaggact
     2641 gggagaccac cttcgctgtc aacacgcagg gggtgtttca tgtctcccgc gcggttgccc
     2701 ggcgaatggt gccacgcaag accggggtca ttgtcactgt tgcctcgaat gcatccggaa
     2761 ccccccgcat gcagatggcc gcgtacgctg cctctaaagc cgcctccgcc atgttcacca
     2821 agtgcctggg attggaactg gcccagcaca acatccgctg caacgtggtc tccccgggct
     2881 ccaccgacac ggcgatgcaa cgcgcgctgt ggacggacga gcgcggcggg gaagcaacca
     2941 tccacggctc cctggaaacc ttccgcttgg gcattcccct gcgccgactg gccacccccg
     3001 ccgacatcgc cgatgcggtg gtgttcctca cctccgaccg agcccgccac atcaccatgc
     3061 acgatttgtg tgtggatggc ggggcgaccc tgggcgtcta ggaagcgctg aagtctcgtt
     3121 tcacgcactc ccctggcctg aggtagcggg cgatggggag tgatcccacc tgatgttgat
     3181 aacgattact aatttcaaca tctctgaagt attgcctcag gagagtgcct gtgatgaccg
     3241 aacgtcccat gtcgccgcag aagctggccg cgcaattgct cgagagttac gaggccggct
     3301 catcattctt ctttgccacc cccaagcgga ccatgttggc acggggcacg ttcgccaccg
     3361 tgccgcacat cggcggcgcg gacgcacttc agcgtctgcc ggagcgagtg gccgcagtcc
     3421 tcaacaacgc gcgggaggct gcccacgaca ttccggtggc agtcggcgcg gtgcccttcg
     3481 acggttcaat tcccgcccag atggtggtcc ccatgacgct tcagcgggcg ggccccctgg
     3541 tattcgacac cgacgtgccc gtgcaccagc ccctggcggc acgttacacg gtccaacccg
     3601 tgcccgagcc cgcggcctac ctcgacggcg tcacgcaggc attgaagctg atgcagaccg
     3661 gctctctgcg caaagtggtg ttgtcccgct ccctgcacct gagcgccacc acgccgattg
     3721 atcttccgca gttgctgcgc aacctggccc agcgcaaccc ctctgggtac accttcgcgg
     3781 tggatctgcc ccccggggcc acccaggccg cgggcggact caggcgtacg ctcatcggcg
     3841 ccagccccga attgctggtt tcacgctccg gtctgcaggt cctcgccaac cccctggcgg
     3901 gctccgcggc acgcagtgcc aatcccatcg aggatcagga gcgggcagcc acgctgctca
     3961 aatcatccaa ggatctccac gagcacgccg tggtcatcga agcggtcgtg gaggccatgc
     4021 ggccctactg caagaagctg gatgtgccct cgggcccctc gctggtcagc acgcaaacca
     4081 tgtggcacct gtcgagccgg atctgcggcg agttggcgga cccatcgatt acctcgctgg
     4141 cgctggcggt cgcgctgcac cccactcccg cggtgtgcgg ctaccccacc gagttggccc
     4201 atgaggcgat caccacgatc gagccattcc agcgaggctt ctacacgggc acggttggct
     4261 ggtgcgatgc gagtggagac ggccagtggg ccgtgaccat ccgctgcgcc gaggccgacg
     4321 agcgcacgct gagactgttc gcgggggcgg gcatcgtggt gggttcgaag cccgagtccg
     4381 agctggccga gaccgaagcc aagttccgca ccatgcttca agcgatgggg ctgggccaga
     4441 acgcagaggt gcagtcgtga cctcgcccag ccctcagcgg gagccttccc ttcttccagg
     4501 ctgcacggcc tggcccgagg agtacgccgc tcactaccgc aaagcgggct actggcgtgg
     4561 agagaccttc ggacagatgc tgcgcgagcg cgcccagcgc cacggagacc gcaccgcggt
     4621 ggtggcgggg acgcagcgct ggagctatcg cgagctcgac gaaagaaccg accggttggt
     4681 ggccggcttc cacgccctgg ggatcaagcc cagggaccgc gtggtggtgc agcttcccaa
     4741 caccgccgaa ttcttcgagg tgatcttcgc gctgtttcga ttgggcgcgt tgcctgtgtt
     4801 cgcgcttccc gcgcaccgca gcgccgagat caactacttc tgcgagttca ccgaagcagt
     4861 ggcctacgtc atccccgaca agcactcggg atttgactac cgcacgctgg ccgagaaggt
     4921 gcgcagcgca gtcccaggct tgcgccacgt ggttgtcgtg ggcgaggcgg ggccctttac
     4981 ctccctgagt cagttgtacg cgtcaccggt cgatctgccg gggcccatcc ccagcgacgt
     5041 ggcctttttt cagctctcgg gcggcagcac gggcgttccc aagctcatcc cgagaaccca
     5101 cgacgactac atctacagcc tgcgcggcag cgtcgagatc tgccagctcg atgagaccac
     5161 cgtgtacctg tgcgcgctgc ccgccgctca caacttcccg ctcagctcgc cgggggtgct
     5221 cggaaccctg tatgccggcg gaaccgccgt gatggcgctg catcccagcc cagaccaagc
     5281 ctttcccttg atcgagcgtg agcggatcac cttcaccgcg ctggtgcccc cgctggcgat
     5341 gatctggatg gatgccgcca aggcacggcg acatgatctg tctagcctga aagtgctcca
     5401 ggtgggcggt gcccggctca gcaccgaggc cgctcaacgg gtgcgcccca ccctgggatg
     5461 cgcacttcag caagtctacg gaatggccga ggggctggtg aactacaccc ggctggatga
     5521 tcccgacgaa ctcgtcatcg ccacccaagg caggccgatc tcacccgatg atgaaatccg
     5581 gatcatcgac gaggacggtc gcgacgtcgc tcctggagaa accggccagc tcctgacccg
     5641 cggtccctac accatccgcg gctactacaa tgccgaggcc cacaatgccc gggcgttcac
     5701 atccgatggc ttctattgca ccggcgatct ggtgagggtc actccggaag gctacctggt
     5761 ggtggaaggt cgagcgaagg atcagatcaa ccggggcggg gataagatcg ccgccgagga
     5821 ggtcgagaac catctgctcg ctcacccctc ggtccatgac gccgcggtga tttccattcc
     5881 ggatcccttc ttgggcgagc gcacctgcgc gttcgtcatt ccccgcgaag ccccgcccac
     5941 ggctgcgact ctcacctcgt ttctgaggga acgcggactg gcggcttaca agataccgga
     6001 ccgtgtcgaa ttcgtcgcca cattccccca aacaggcgtc ggcaaagtca gcaagaaggc
     6061 actgcgcgaa acactcgctc accgataggg gttttcccag tgcacggaag aagtcttccc
     6121 acacgcatcg ctgttcccaa cccccaagca cgaaagagtc catccatggc acttcccgcc
     6181 atcgccccct atcgcatgcc cagcgcggcc gatctgccca cgaacaaggt gtcctggaca
     6241 cccgatcctc aacgcgcggt tctgctgatc cacgacatgc agaggtactt cgtggacgcc
     6301 ttcaccagtg gggcctcgcc cgtgaccgag ctcgtggcga acatccgcca actgcggcag
     6361 cactgcatct ccgtgggtat tcccgtggtg tactcggctc agcccggtgg gcagacgccc
     6421 gagcagcgcg gccttctgct ggatttctgg ggagcaggga tcaacggggg gccccaccag
     6481 aagcagatca tcgacgcgct gacccctgcc gaaggcgaca tcgttctgac caagtggcgc
     6541 tacagcgcgt tcaacaggac gcagctcatg gacatcctgc gccaaagcaa gcgcaaccaa
     6601 ctgatcgtct gcggcatcta cgcgcacatt ggctgcctcc agaccgccag cgaagccttc
     6661 atgaacgagg tgcagccgtt cttcgtggcg gacggcgtcg ccgacttctc ctgggaaaac
     6721 caccagatgg cgttgaacta cgcagcgcgg ttgtgcgccg tcaccaccac cacgcagcag
     6781 ctcatcgacc aactgcggcc ccaggccacc cgtgggggcg tgcccttgag ccgacagcag
     6841 gtgcgcgcgg atgtcatcga gatgctccag caggatgcgg cgctcggcga tgacgagaac
     6901 ctccttgagt gtgggctcga ttcgattcgc ctcatgaccc tggtcgaacg ctggagaaat
     6961 gctggaaccg aggtcacctt cgtggagttg gccgagcgcc ccaccctggg cgactggtac
     7021 tcgatgctga cctccatcgc ccaaccccct cccgtggaag tggccgcggc gcttcagcgg
     7081 ggcgtccgcc ccaccgcgta gccatcgagc cgtggggcca tcccacctcg atgtttttca
     7141 catccagagg gagtactgag cgatgcggga ttcacaggaa actcgtcggc cgctgtcggc
     7201 ggcccagcac ggcatctggc tgggtcagca gttcgatctc aagagcccgg tgtacaacgc
     7261 cggcgagtgc attgagattt gcggccccgt ggaccccgcg ctgttcgagg cagcggtgcg
     7321 tcaggctgtc cgtgaagccg aagcactgca tgtgcgtttc gtggccagcg aggagggccc
     7381 gcagcaactg cttggcctcc agacagactg ggtgctgcac acggccgatc tcagcgagag
     7441 tcccgacccc tgggcagcgg tgcaggcctg gatgaaggca gatctggccc aaacagtcga
     7501 cctcagccgg ggaccgctct tcacggaagc cctgttcaag gccgcacccg accggttctt
     7561 ctggtaccag cggatccacc acatcgccat ggatggcttc ggtttctcgc tgctggcccg
     7621 gcgggtggcc gaagtgtaca ccgcgctggc cgcaggccgc cccatcacgg gaggctttgg
     7681 ctccttccag gccgtgctgg atgaggacgt ggcgtatcgg aacgggcctc agcacgagct
     7741 tgaccggacc ttctggacgg agcgcttcgc cgatcggccc accccggtca gcctcgcctc
     7801 ccctgccccc atgtctccca gcttcgtgcg ccaaacgcgc tttcttcccg cgcaaagcat
     7861 ggagcggctc caggcggtgt cacggcccgc gggcctgaac tggcctgatc tggtgcttgc
     7921 ggccacggcg gtctacctgc accggctcac cgacgcgaca gaggtagtac tcggcctgcc
     7981 agtgatgact cgacttggct cggccgcgct gcgcgtgccc tgcatggcca tgaacatcgt
     8041 tcccctgcgc gtgcccgtga gccccgaggc cagcttgctg gatctggccc gagggatcgc
     8101 cgcagaggtg cgcgccatgc ggccccacct gcgctaccgc tacgagcagc ttcgccgcga
     8161 cctgaagttg gtgggaggac agcggcggct gttcggcccc gtggtcaaca tcatgccgtt
     8221 tgactacgcc ctgcgcttcg cgggaatgcc caccatcgct cacaacatct ctgccggccc
     8281 cgtggaagac ctgtcgatcg gtctgtatgc ccgggccgat ggcaagggcc tccgggtaga
     8341 cttcgacgcc aaccccgcct gttacgaggc caaggcactg gaatcccacc caagtgcctt
     8401 cctcgaactg ctggaggcac tcaccgcagc ccccgaccag gcagtggggc gggattcagg
     8461 cagcctctcc tcgtcttcca gcaaggcccc ctcgcttgcc tccgtactcg atggtgggcc
     8521 gcttcccgta gccgcccagc cggttctgca actgatcgcc gagcgagccc tcgagcaacc
     8581 cgatgcgatc gcggtggaac acggtcaaca ccagatgagc tatcgggagc ttctccaaag
     8641 cgcgcaggcg ctgtccgctc agctcatcag cgctggggtg cagcccaaca cagcggtggc
     8701 agtcatgctg ccccggggac tcgatgccat cgtggcgagc ttgggcgtgc tgttctccgg
     8761 cgcgggctat ctgcccctcg atccctacgg tccctcatcc cgaacagcgg ccatcctcga
     8821 ggatgcgaag cccgcgctga tcatccagcg ctcaacgcct gatgcggatc ccctctcccg
     8881 agggaacctc gtcattcgac agaacgagca ggcaccagcc gccgcccctt catctcgaac
     8941 cctgccccag acctcgggcg agcaccttgc ttacgtcatc tacacctccg gctcgacagg
     9001 ccagcccaac ggcgtgcaga tcagccacga ggccctggct cacttcgtgg cgggagcgac
     9061 ccatcgctat ggggtgcggc gcgacgaccg ggtgcttcaa ttcgcccccc tccacttcga
     9121 tgccagcgtg gaggaaatct tcctgaccct gtgtgcgggc gcgaagctgg tgcttcgcac
     9181 cgaggagatg ctccaatcgg tctcccggct cctcgacgcg tgcgccgagc acggcatcac
     9241 cgtgttggac ctgcccacgg cgttctggca cgagctggcc tacagcgtct ccacgggcgc
     9301 ggcccggttg ccctcttcca tccgcctcgt gatcatcggc ggagaggctg cgttgcctga
     9361 acgggtcgcg cgctggcgct ctgccgtcag ccccgaggtt ctgctgctca acacctatgg
     9421 ccccaccgaa gccactgtgg tggccaccac cgccacgctg agtggtcccg cccctgcggg
     9481 gactcccgaa gaagagatcc ccattgggcg tccgctcccc ggagtgcgtg cggccctaat
     9541 cgatgcgcaa gggaaactgg ctgcccctgg ggcagaaggt gagctgtacc tgctgggcgg
     9601 tggcctggca cggggatacc tggggcgccc agagctgaat accgcgcgct tcaccacgct
     9661 tggcatgctg tcggatcgtc cgcgcgccta ccgcacgggc gacaaggccc gcgtccgtga
     9721 ggacgggcaa ctggtcttcg tgggccgcgt cgatgacgag ttcaagatca gcggccaccg
     9781 gatcgatccc accgaaatcg aaaccgtgct gctgagccac tcgggcgtgc gtgaagccgc
     9841 cgtggtcgga cagatcctcc ccggcggaac gcgccgactg tgcgcgcaca tcgtcgccga
     9901 gatgcccgtc ccagccaccg ccgaattgcg ccgacacctg ttgtcagaac tgccagcggc
     9961 catggttccc agtgccttcg tgttcgccga gaagctgccg cgcaccagca cgggcaagct
    10021 ggatcgcaac gcactgcgcc tcgtgcagcc tcccgaggag gcgaccccca ctgccacaac
    10081 gaccccgttc gagcgcatgg tgctccaggt atgggaacag gtcctgggcc tgagccgcat
    10141 caccgcgcag gacgatttct tcgagttggg gggacagtca ctccagacga tccaggtcgc
    10201 caaccggctc agcgtcgcat tgggtcgcga cgtgcctgtc gccacggtgt tccggtaccc
    10261 caccgccgcc ggtctggcgc aggcactgga acacggagag cagcacagcg tggaaggcga
    10321 aggcatctcc aaggccatgc tcgcggacgc ggaactgccc gaagagatcg tcccgcgcct
    10381 gccaacgccg ggcgccgagg cccctctcgc gccaagtcca gggccagccg cccccttgcg
    10441 gcaggtgctg ctcacgggag ccaccggttt cgtgggggcg cacctgctcg atcagttgct
    10501 gcgccagacc caggcgaagg tggtgtgcct ggttcgcgcc cgcgacgagg cgcacgcgat
    10561 ggagcgactc cgcgaggcca tgacaagtca gaggctgtcc acggccagcc tctccgagcg
    10621 ggtcctggcc ctgcccgcag acctcggcca gccgtggttg gggctgagct ccgcgcgctt
    10681 ccatgggctg gcggcggagt gtgacatgat cctccacaac gccgccgtgg tcagcgtcgt
    10741 gcgcgagtac ggcagcctcc aagccaccaa cgtacggggg acccgcgaac tcctccggct
    10801 ggcggcttcc gtgcgcccca agcccctgca ctacgtctcg acgctggcgg tggcccccca
    10861 ggccaacctc agcccagaag tcccagaagc gttcgtgccc gcccacccag gtctccgcga
    10921 cggctatcag cagagcaagt gggcagccga gcgcttggtc gagcaagcct ccgagcgtgg
    10981 cctgcccgtg acggtctacc ggcttggacg ggtatccggc gccctggaca gtggcattgt
    11041 caacccgcag gatctcgtct ggcgcatcct gctggcgggc atcccagcgg gggcgttgcc
    11101 ccaactcgat gtgggtgaag tgtggacacc ggtggactac gtcgcgcggg cgctcgtccg
    11161 gctctcgctc gtcccacgcc ccggtacggt cttcaacctc acccccgcac ccgaagtgcg
    11221 gctgagcgag gtgttcggtt gggtccagga ctacggctac cccgtcgcac tgtgtccggt
    11281 tcccgagtgg cgcacccgcg tggcccaatc cacggggagt gctgaaaaca gcaccacgct
    11341 ggccttcttc gacctgcgcg caggcgcagc agaacccacc ttcggactgg gaaccattcg
    11401 cagcgagcgc gtactccagg ccttgtccga cacggggatc tcctgtcctc gaaccgatcg
    11461 tccgcttctc caccgctacc tggattactg tgtcgggcaa ggtctcctgc agaggcctcc
    11521 ggaacaccgg taaagacaca cagtccatct ccatgtcctc acatcgaaac ggcccttctg
    11581 tgttgaaaca aaattggact cccggctcct ggagagcgaa gcccgtcaag cacatgccag
    11641 acgactaccc cgacgctcgc gaactcgcgc gcgtcgagga ggaactgtcg cgccttcccc
    11701 ccctggtctt cgcggaagag acgcgccggc tgaccgccgc actcgggcaa gtcgccgaag
    11761 gccaagcttt cctgttgcag ggaggagact gcgcggagag cttcaaggag ttcacgaccg
    11821 acaatgtccg cgacagcctg cggctgattc tccagatggc ggtggtgctg accttctcgg
    11881 gcggacgccc cgtggtgaag gtcggccgca ttgccggcca attcgccaag ccgcgcagcg
    11941 gcgcctccga aaccatcgaa ggcgtcaccc tgcccgccta ccgcggagac atcatcaacg
    12001 gcatggagtt cgagcctggc gatcgcatgc ccgatcccaa acggctgctc aaggcctacc
    12061 accaatcctc ggacaccttg ggcctgctgc gcctcttctc ccaaggcggc tacgcggacc
    12121 tctgcaacat gcaccgctgg accttcgact tcgtcgcgga cagcgtccag ggcggccagt
    12181 accgaaagct ggcggacaag attctcgaat ccctgcgctt catgagcgcg ctccacgtga
    12241 gtccaggcca gcaaatgccc ctgaaccgcg tggacatgtt caccagccat gaagcgctgc
    12301 tgctgaactt cgaagaggcc atgacccgag cagaccccat ctccggggat tggtacgaca
    12361 cctccgccca tatgctgtgg atcggcgaac ggacgcgcca gctcgatggg ggccacgtgg
    12421 agttcatgcg gggcatccag aatcccatcg gcctcaagtg cgggcccacg atggagcccg
    12481 aggatctcct gcggctgatg gacatcctga accccgacgc catccccggg aagctgacgc
    12541 tcatcggccg gttcggggcg gacaaaatcg cagagcgcct gccccggttg atggcagcca
    12601 ccaagcgcga tggacgcccc gtggtctggt cgaccgaccc catgcatggc aatacgctca
    12661 aagcgcgcaa cggatacaaa acccggccct ttgatcgcat cctgtccgag gtgaaaacat
    12721 tcgttcaggt cgccacctcc gagggggtcc atccgggagg gctccacctg gaaatgaccg
    12781 ggcagaatgt caccgagtgc ctgggcggcg cgcaggcggt caccgaggat gacttgtcca
    12841 gccgctacca cacgcattgt gatccgcggc tcaacgccaa tcaggccctg caactggcct
    12901 tcctggtggc cgacaagctc cagtctttgc gggtctccga agcctgggcg gccgtctcga
    12961 cagactcctt gacagagatg tctggaaagg agtaccacgc ggcaccgaaa tgaaaatgag
    13021 aagcattttc atagtctctt ccccgttcgg gacacccact cgggaaagag cacttgcacg
    13081 cttgtgccgc accgctctcc tggcagcgct cctcacctcc cgcctggccc aggcgcaaga
    13141 gcagagcccg gagcgcgcaa cgcctcaggc cccgagcggt tccgcacccg cgccgcagcc
    13201 gtccgaagca ccgcccgccg cgcctgtcgt tgagatgccg aagctcctgg agatcgtcga
    13261 agcgatctac ccagcccagg cgaagcaaga tcgtctcgaa gccaaggtgg ccctccggct
    13321 gaccctcgac gcgcaaggtg tcgtcaagac ggcagaggtc ctcggacccg tcggtcacgg
    13381 cttcgatgag gcggcccaag aggccgccct ccgcttccga ttcgagccag ccaaacggaa
    13441 cggaacgacg gtgcccgcgc gcgtcgtcta tacctacgaa ttccgcctgc cccccccgcc
    13501 tacgcctccc agcgcacagc cctcgggcca agcagccgcc tcggagtcgt ctgactcttc
    13561 cttcggagag accatcgaag tctcagccgg gggagaatcg gtggcccagc ggcggcgcca
    13621 gtccgccgaa gccgtgcagg tgctcgaggt cggcaccctt cagcgagagg ccgtggatct
    13681 gggcgaggcg cttgctcgga cggagggagt ctccgtgcgg cgctcgggcg gactgggcag
    13741 tacctcgcgg ttctccatcg cgggactcac ggacgagcag atccgcttct tcatcgatgg
    13801 tgttcccctg gagctcgcag gctacggcgc cgggctggcc aatgtcccgg tcaatctcgt
    13861 ccagcgagtc gagacctacc agggcgttgt tcccatccgc ttcggcgcag acgccctcgg
    13921 tggcgcggtt catctcgaga ccgaccagaa tttccaggga ctgggggcct ccgcatcgta
    13981 tgagttcggc tcgttcgaca cgcaccggct cacggccagc atccggcagt tgcacgagcc
    14041 cacggggttt cttctccgag ccagcggttt tttcgatacc acccggaacg attatctcgt
    14101 cgatgtcgaa gtcgaagccg ccgatggttc cggtagaccc gtgcgtgcgc gcgttcaccg
    14161 gtttcacgat ggctaccggg ccggcggcgc gggcatcgag gccggcttcg tggatcaatc
    14221 ctgggccaga cgcctgctcc tccgggtctt cacaggcacg tatgacaagg atctccagaa
    14281 cgacatcgag atgagcgcgc cctatggcga agtggaatac ggagaaacct ccggaggctc
    14341 cacgctgcgc ttcgagcaga tctactcgaa tgggctctcg gtcgacgcga tcgcgggtta
    14401 cacctatcgc cgcaatcacc tcacagacct cagtcagtgc gtctacgact ggtatggacg
    14461 ctgcatcctc gtgctcccgc agccgggagt cctcgagggc cgtcccatcg agagaaccat
    14521 cggacagcac accgggtttg cacggctgaa cttcggctgg aatgtctccc cctcgcagaa
    14581 attccgattg tccctcgcgc ccacgttcgt ggatcgggcg ggtgaggacc ggcagcttca
    14641 agaggcccaa caactcgacc cgctcgacgg cgaacgcaat ctgttctccc tggtcgccgg
    14701 cctcgaatat gaaatcgatg ctttcgagga acgcctcgag aacattctgt tcgtcaagga
    14761 ctacctccag cgggcctacg gtgagaaacc gctcgacggt ggcgaattcg ccatcacaaa
    14821 gagaaacctg caccaagtgg gggtgggtga cagcgcccgt ctgcgcttcg cccccggact
    14881 ctacgccaag gcctcttatg agtgggccac tcgcatgccg cgtccggacg agttcttcgg
    14941 tgatggactg ctcgtcgtcg aaaacctcaa gctacagcct gaaaccagtc acaacctcaa
    15001 tctcgggctc acgtacgagg cccccagcac tcccgcggga gattttcggg ccaacgtgac
    15061 agggttcggg cgcctggcgg atcagctcat ccttctcgtg ccccaaccca gctatttcgt
    15121 ctatgagaac gtcttcgcgg cccgttccct aggggtcagc ggcacggcag gctggatctc
    15181 tccgggacga tacgtttcgc tcgacggcaa cgccacctgg caggatttcc gcaacacctc
    15241 cagcgagggg gtttatggcg ccttcgtgga caagcgcatt cccaatcgac cgtacctgtt
    15301 cgccaatggc agcgcccgct tcgaactcag caacctgatg aacccgcgcg atgaactcgc
    15361 cctcacttgg aacttacgct acattcacaa gttcttccga gcctgggaag ggtttggaaa
    15421 ggttgacacc aaggatgtga ttgcttccca atgggtgcac tcgctctcgc tgacctacgt
    15481 cacccggagc gattccgcca cgttgacctg gtcggcggac gcccagaatc tcaccgacgc
    15541 aaaggctttt gacttctacg gcgtccagcg tcccgggcgc agcctgtttg ccacgctcac
    15601 agtggatttc gaaacctgac cgcaacaccc caacccgaag agtaacccca tgaacctcac
    15661 gaagacgctt cgccccgtac ggtggctcgc cgccgtgctc gccctcccct tgctcaccgc
    15721 gtgtggcgat gacgaggaag tcaccccccc gcctcccccc tcaactgctt cgcaatacgc
    15781 cgtcgtgact caagtcacct cggacagtgg ttcctcggcg agctacgtgg tcgtgaccga
    15841 ttcggtggat cacaccgaga cgctgtctct gaccaatgcc attgaagtca cgggccgagc
    15901 cctcgtgttt ggtcctccga agaaggatca tttcttcgtg agctctggca agtcggtcat
    15961 ccgctacaac ctgacggaat ccgggactcc ggagaagggc gcgactgtcc tcttctcgga
    16021 cctgcccgag gacatcaccg agtatcagca ccagttccgg ttcatctccg agaccaaggc
    16081 gtacttcttc gacggttcga ccactcaggt catcgtctgg aatccctcgg ccatgacggt
    16141 cacgcgccga gtccccttcg gtgacgtcaa gcccgccaac acggtgctgt ccttctcgtc
    16201 gcagcctctg gatgtcgcca atctggtcat catgccgctg ggctggcgcc cgagcacagg
    16261 gaccacgatc accaagcagg cgggcgtcct cgtggtcgac ccgaacaccg atacgctgca
    16321 gttcgtgaag aaggagttca aggaggggga ggggtgtggc tacgtgcgcg atggcgtcgt
    16381 cggcaaggac ggaaaggtct acctctccac ggaggcctac ggctcggcct cgtaccgggt
    16441 ccaccgcgat gatccggcca cgctcaagcc gtgcctgctc cgcttcgatc cccagaccaa
    16501 gaccttcgac gacttcttcg tggatctcac cacgctgagc aacggcgctc ctgccggctc
    16561 tgtgctgcag gggcccggtg gaaagacgta cctgcgcgtt ctggatgaag cgtccttcac
    16621 gggcacgatc acgaaggaga cccacccccg gctcctggcc agcgcggtcg cgtggaagtg
    16681 gtgggagatc aagctcgaca ccctgacggc cacccccgtc agcacgctgc ccgctgccat
    16741 ggggagcacc ttcctcttcc ccgccaatga ccgggtgctc ttcaccaact tcacgagcaa
    16801 ctcccagacg gagttgcgcg agttgacgga cgcgagcggc aaggtggcca ccgtcacacc
    16861 gggccgcacc ttctccttcc tccaggtgcg ctgagcgtcc agtcgccact gaaggaggac
    16921 gggcagcccc ctgaaatagg gggctgctct tccatccgcg gggggtgacg cctcaccgtc
    16981 cctctcgcgc ctcccccctc cttgccaaac gccgcgctcc tccagtacat tgccgcgcgg
    17041 ctgataagaa tgattatcat tatcgtttct aaattcatga ctgtcccgag cggcgccctc
    17101 ccgcgactcc caggaagtga agcgtgagcg cgtcctctgc accgggttcc gagcgtcggc
    17161 tgctgtggct gctagcggcc gtgcagttca gccacctcat ggacttcatg atcgtgatgc
    17221 cgctcggccc ggagttcatg cggctgttcg gtatttcggc cgcgcaattc ggggtgctgg
    17281 tctccgccta tacgctggcc tcggcggcga tgggtctgtt gggcgtgctg tggctggatc
    17341 ggttcgatcg gaaacggacg ttgctggccc tctacggcgg gttcatcgtc gccacgctga
    17401 tgtgcggcgc cgcgcagagc cacatcgcgc tgctggtggc cagaaccctg gctggtgcct
    17461 gcgcggggct gatgggcgcc gtcatcatgg ccatcatcgg cgacctggtc cccccggagc
    17521 gccgtggcaa tgccattgga acggtgatgg cgtcgctggg cttgtccgcg gtggtgggcg
    17581 ttcccctggg cctcgggctc gccaacctct ggggctggaa gatgcctttc tgggcgattg
    17641 gcggtttcgc cagcgtgatg tggcttggcc tctggaaggt cctgcccccg ctccgccagc
    17701 acctctccgc gtctcgggaa caggtccgtg gagactcgct catctccctc tggacgccca
    17761 gcctggccct gggctggttg ttgaccttca gcgtggtgat ctccagcttc cttttgattc
    17821 cgtacctgag cccctacatg gtgggcaatc tgggactgga gaccgcgcag cttccctggg
    17881 tgtacctggg cggcggcgcg gccaccctgc tgtgtacccg ctggatcggc cgcatgacgg
    17941 atcgccatgg ccccgtgcgc gtcctggcct cgctgctgat gggcacgatg gtgccccacc
    18001 tgctcttcac gcacctaccg ccctcgccat ttcccgtggt ggcgctgatc ttcgccttgt
    18061 tcatgtcgct gacctccagc cgggtcattc ccaccattgc cctgatctcc gcccgcgtgc
    18121 cgccctcggt ccgtggccgc tatcttgcgg tcaacatggc cgcgagcgat ggggcctcgg
    18181 gaatcgcggc ctggatgagc gggctgatga tttcgacagc caccggtggc gcgctggagg
    18241 gctttggcca aaccggctgg atcgcggtgg gcgtctcggc cttcgcgctc tgcgtgctct
    18301 ggacgctcgg gcgcagcacc gtccggttga gcgccgcgcc gacctgattt cgtgaaccgc
    18361 agtcatcgac aacggacaaa ggaagctctg atggatacgc actcgaagag acacccctcg
    18421 ctgccccggc ccattcaagg cgagatgaag ctcgagaact cgaaccgtct gctcgcggag
    18481 gccaagcgcc tgattcccgg cgtcacgctg tcgatgatga agcggcccga gcacttcgcc
    18541 cccgacgcgt tcccggtcta cctcgcccgg ggccagggag cgctggtgga ggatgtggat
    18601 ggccagcagt acatcgactt catcggtggg ctcggggcca acatgctggg ccacaaccac
    18661 cccgcggtcg tggagagcat tcgcaagcac ctggacgagg ggctcatcca ctccctgccg
    18721 acgcccgttg agctcagcgc ctcgcagacc ctgatcgaaa tgattcccgg cgcggagatg
    18781 gcgcgattct tcaagaccgg ggccgatgcc acctctgccg cgatgcggct ggcgcgcatc
    18841 atcaccggca aggagcgcat catcaccgtg ggctacaacg gctggcatga tcacttcatg
    18901 gtcggcacgc ccggcgtccc ggccgtgatg tcccagtaca cgattcgcat gccgctcttc
    18961 accccgcagg acgagacggc cctgctggcc tgtatcgggg agaatgccaa gcagcttgcc
    19021 gccgtgctga tttcgatccc gttcaaccgg tgtctgagcc gggagttcat gcaccagttg
    19081 cgcgccgcgt gcaccgctca cgaggtgctg atggtgcagg acgaggtcat caccggcttc
    19141 cgcctggcgc gcggtggcgc gcaggaattc ttcgacgtga aggccgactt cgtctgcctc
    19201 tcgaaggctc tcgcggcggg catgccgctc tcggcggtgg ccgggccggc caagcacctg
    19261 agcaagctcg gagccatgga ggtccaggtg tcgaccacct tcggtggcga gatgttgtcg
    19321 ctggccgtgt gcgaagcgac cctcaaggag taccgcaagg ggggctacat cgagcaactc
    19381 gccgcgctgg gcagccgact gcgcacgggc atcaacgcga aggccgagaa ggcgggctcc
    19441 ccgctgaggg tgctcggcta cgactccatc cccttcctcc tcttcgacaa gaaccccacc
    19501 gagcacgcca agcgaatgca gccgttccag gcgggaatgg ctcgccgagg catcctgctg
    19561 cgccgcgacg tgaacttcat cagcgcggtg cacacccagg agcagatcga ctacacgatc
    19621 gagatggcgg gagaggtgtt gcagtctctc tga
//
