BGC0001346: bananamide 1 biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 1 - 34,679 nt. (total: 34,679 nt).
This entry is originally from NCBI GenBank KX437753.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001346
Short description bananamide 1 biosynthetic gene cluster from Pseudomonas fluorescens
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: partial
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "Pseudomonas fluorescens strain BW11P2 (Bananamides). NCBI accession(full genome): LRUN00000000. Bananamide biosynthetic gene cluster: KX437753."
Biosynthetic class(es)
  • NRPS (Type I)
Loci
KX437753.1
via Gene expression correlated with compound production
Compounds
  • bananamide 1
  • bananamide 2
  • bananamide 3
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
bananamide 1 Evidence: NMR, Mass spectrometry
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C55H97N9O14
bananamide 2 Evidence: NMR, Mass spectrometry
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C55H95N9O14
bananamide 3 Evidence: NMR, Mass spectrometry
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C53H93N9O14
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AOA33119.1
  • banF
 1 - 1066 (-) RND efflux system, outer membrane lipoprotein
  • Transport
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  • AOA33120.1
  • banG
 1126 - 1920 (-) LuxR family DNA-binding response regulator
  • Regulation
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  • AOA33121.1
  • banA
 2411 - 8821 (+) Nonribosomal peptide synthetase
  • Scaffold biosynthesis
  • Other in vivo study
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  • AOA33122.1
  • banB
 9072 - 22079 (+) Nonribosomal peptide synthetase
  • Scaffold biosynthesis
  • Other in vivo study
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  • AOA33123.1
  • banC
 22076 - 30376 (+) Nonribosomal peptide synthetase
  • Scaffold biosynthesis
  • Other in vivo study
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  • AOA33124.1
  • banD
 30443 - 31591 (+) RND family efflux transporter MFP subunit
  • Transport
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  • AOA33125.1
  • banE
 31588 - 33552 (+) ABC transporter ATP-binding protein
  • Transport
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  • AOA33126.1
  • banH
 33610 - 34383 (-) LuxR family DNA-binding response regulator
  • Regulation
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Biosynthesis information

Biosynthetic modules

Name
1
Type
nrps-type1
Genes
banA
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Starter), adenylation
Name
2
Type
nrps-type1
Genes
banA
Substrates
aspartic acid (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
3
Type
nrps-type1
Genes
banB
Substrates
threonine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
4
Type
nrps-type1
Genes
banB
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
5
Type
nrps-type1
Genes
banB
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
6
Type
nrps-type1
Genes
banB
Substrates
glutamine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
7
Type
nrps-type1
Genes
banC
Substrates
leucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (Dual), adenylation
Name
8
Type
nrps-type1
Genes
banC
Substrates
isoleucine (evidence: Sequence-based prediction)
Integrated Monomers
Domains
condensation (LCL), adenylation
Annotation changelog

Entry version: 3

Date
Changes
Submitters
Reviewers
2022-09-15
Add missing citation (issue #6)
  • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Corrected NRP module activity
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Changed amino acid substrates to lower case
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
2016-09-03
Submitted
  • (ID: OQMFGYOK6ZQZ6D5FULTTAUDO)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Detailed domain annotation
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