BGC0001351: cahuitamycin A biosynthetic gene cluster from Streptomyces gandocaensis
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Location: 1 - 41,608 nt. (total: 41,608 nt).
This entry is originally from NCBI GenBank KU363800.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001351
Short description cahuitamycin A biosynthetic gene cluster from Streptomyces gandocaensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Cahuitamycin C uses 6-methylsalicylate as the starter unit synthesised by a 6-methylsalicylate synthase encoded elsewhere."
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KU363800.1
Compounds
  • cahuitamycin A
  • cahuitamycin B
  • cahuitamycin C
Species Streptomyces gandocaensis [taxonomy]
References
Chemical products information
cahuitamycin A
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C27H37N7O11
Chemical database entries
NPAtlas
cahuitamycin B
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C27H39N7O12
Chemical database entries
NPAtlas
cahuitamycin C
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C28H39N7O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AMK48246.1
  • cahMO
 1 - 1326 (-) L-ornithine-5-monooxygenase
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  • AMK48223.1
  • cahFT
 1410 - 2363 (+) formyltransferase
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  • AMK48224.1
  • cahT1
 2808 - 3824 (+) putative iron(III)/siderophore ABC transporter substrate binding protein
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  • AMK48225.1
 3889 - 7368 (-) nonribosomal peptide synthetase
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  • AMK48226.1
  • cahB
 7426 - 15306 (-) nonribosomal peptide synthetase
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  • AMK48227.1
  • cahC
 15303 - 19814 (-) nonribosomal peptide synthetas
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  • AMK48228.1
  • cahD
 19811 - 22984 (-) nonribosomal peptide synthetase
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  • AMK48229.1
  • cahE
 22984 - 23202 (-) MbtH-like protein
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  • AMK48230.1
  • cahF
 23206 - 23694 (-) aspartate 1-decarboxylase
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  • AMK48231.1
  • cahG
 23736 - 24548 (-) alpha-beta hydrolase
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  • AMK48232.1
  • cahH
 24576 - 25865 (-) siderophore export protein
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  • AMK48233.1
  • cahI
 25874 - 27208 (-) salicylate synthase
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  • AMK48234.1
  • cahJ
 27449 - 29083 (+) salicylate-AMP ligase
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  • AMK48235.1
  • cahT2
 29073 - 30131 (+) iron ABC transporter permease
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  • AMK48236.1
  • cahT3
 30128 - 31189 (+) iron ABC transporter permease
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  • AMK48237.1
 31284 - 33128 (-) FAD/iron sulfur cluster binding oxidoreductase
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  • AMK48238.1
 33113 - 34198 (-) putative peptidase C45, acyl-coenzyme A/6-aminopenicillanic acid acyl-transferase
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  • AMK48239.1
 34183 - 35217 (-) putative 6-aminohexanoate-oligomer hydrolase
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  • AMK48243.1
  • cahT4
 35214 - 35969 (-) putative ABC transporter ATPase
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  • AMK48242.1
  • cahT5
 35966 - 36955 (-) putative ABC transporter ATPase
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  • AMK48241.1
  • cahT6
 36952 - 37812 (-) putative ABC transporter permease
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  • AMK48240.1
  • cahT7
 37809 - 38780 (-) putative ABC transporter permease
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  • AMK48244.1
  • cahT8
 38787 - 40343 (-) putative extracellular solute-binding protein
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  • AMK48245.1
  • cahR
 40607 - 41608 (-) LacI-family transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Un-retire entry
Detailed domain annotation
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