BGC0001351: cahuitamycin A biosynthetic gene cluster from Streptomyces gandocaensis
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Location: 1 - 41,608 nt. (total: 41,608 nt).
This entry is originally from NCBI GenBank KU363800.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001351
Short description cahuitamycin A biosynthetic gene cluster from Streptomyces gandocaensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "Cahuitamycin C uses 6-methylsalicylate as the starter unit synthesised by a 6-methylsalicylate synthase encoded elsewhere."
Biosynthetic class(es)
  • NRPS (Type I)
Loci
KU363800.1
via
Compounds
  • cahuitamycin A
  • cahuitamycin B
  • cahuitamycin C
Species Streptomyces gandocaensis [taxonomy]
References
Chemical products information
cahuitamycin A Evidence:
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C27H37N7O11
Chemical database entries
NPAtlas
cahuitamycin B Evidence:
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C27H39N7O12
Chemical database entries
NPAtlas
cahuitamycin C Evidence:
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C28H39N7O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AMK48246.1
  • cahMO
 1 - 1326 (-) L-ornithine-5-monooxygenase
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    • AMK48223.1
    • cahFT
    		 1410 - 2363 (+) formyltransferase
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      • AMK48224.1
      • cahT1
      		 2808 - 3824 (+) putative iron(III)/siderophore ABC transporter substrate binding protein
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        • AMK48225.1
        		 3889 - 7368 (-) nonribosomal peptide synthetase
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          • AMK48226.1
          • cahB
          		 7426 - 15306 (-) nonribosomal peptide synthetase
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            • AMK48227.1
            • cahC
            		 15303 - 19814 (-) nonribosomal peptide synthetas
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              • AMK48228.1
              • cahD
              		 19811 - 22984 (-) nonribosomal peptide synthetase
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                • AMK48229.1
                • cahE
                		 22984 - 23202 (-) MbtH-like protein
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                  • AMK48230.1
                  • cahF
                  		 23206 - 23694 (-) aspartate 1-decarboxylase
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                    • AMK48231.1
                    • cahG
                    		 23736 - 24548 (-) alpha-beta hydrolase
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                      • AMK48232.1
                      • cahH
                      		 24576 - 25865 (-) siderophore export protein
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                        • AMK48233.1
                        • cahI
                        		 25874 - 27208 (-) salicylate synthase
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                          • AMK48234.1
                          • cahJ
                          		 27449 - 29083 (+) salicylate-AMP ligase
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                            • AMK48235.1
                            • cahT2
                            		 29073 - 30131 (+) iron ABC transporter permease
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                              • AMK48236.1
                              • cahT3
                              		 30128 - 31189 (+) iron ABC transporter permease
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                                • AMK48237.1
                                		 31284 - 33128 (-) FAD/iron sulfur cluster binding oxidoreductase
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                                  • AMK48238.1
                                  		 33113 - 34198 (-) putative peptidase C45, acyl-coenzyme A/6-aminopenicillanic acid acyl-transferase
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                                    • AMK48239.1
                                    		 34183 - 35217 (-) putative 6-aminohexanoate-oligomer hydrolase
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                                      • AMK48243.1
                                      • cahT4
                                      		 35214 - 35969 (-) putative ABC transporter ATPase
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                                        • AMK48242.1
                                        • cahT5
                                        		 35966 - 36955 (-) putative ABC transporter ATPase
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                                          • AMK48241.1
                                          • cahT6
                                          		 36952 - 37812 (-) putative ABC transporter permease
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                                            • AMK48240.1
                                            • cahT7
                                            		 37809 - 38780 (-) putative ABC transporter permease
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                                              • AMK48244.1
                                              • cahT8
                                              		 38787 - 40343 (-) putative extracellular solute-binding protein
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                                                • AMK48245.1
                                                • cahR
                                                		 40607 - 41608 (-) LacI-family transcriptional regulator
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                                                  Biosynthesis information

                                                  No biosynthesis information available for this record.

                                                  Annotation changelog

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-09-15
                                                  Un-retire entry
                                                  • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Migrated from v1.4
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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