Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001353.1:
Cluster 1NRP / Polyketide113567
The following clusters are from record BGC0001353.2:
Cluster 2NRP / Polyketide12249

BGC0001353, thiolactomycin biosynthetic gene cluster from Lentzea sp. ATCC. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: thiolactomycin
SMILES string: Copy to clipboard
Molecular formula: C11H14O2S
Average molecular mass: 210.298 Da

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

thiolactomycin (BGC0001353). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank LN879412. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. W. Tao, M. E. Yurkovich, S. Wen, K. E. Lebe, M. Samborskyy, Y. Liu, A. Yang, Y. Liu, Y. Ju, Z. Deng, M. Tosin, Y. Sun, P. F. Leadlay. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, vol. 7, no. 1, pp. 376-385

BGC0001353, thiolactomycin biosynthetic gene cluster from Lentzea sp. ATCC. Locus 2. Partial MIBiG entry.

Chemical compounds

Compound: thiolactomycin
SMILES string: Copy to clipboard
Molecular formula: C11H14O2S
Average molecular mass: 210.298 Da

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Modular Type I

Gene cluster description

thiolactomycin (BGC0001353). Gene Cluster 2. Biosynthetic class = NRP/Polyketide. GenBank LN879413. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. W. Tao, M. E. Yurkovich, S. Wen, K. E. Lebe, M. Samborskyy, Y. Liu, A. Yang, Y. Liu, Y. Ju, Z. Deng, M. Tosin, Y. Sun, P. F. Leadlay. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science, vol. 7, no. 1, pp. 376-385