LOCUS       BGC0001366             15462 bp    DNA     linear   BCT 02-MAY-2016
DEFINITION  UNVERIFIED: Streptomyces sp. FJS31-2 anthrabenzoxocinones
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0001366
VERSION     BGC0001366
KEYWORDS    .
SOURCE      Streptomyces sp. FJS31-2
  ORGANISM  Streptomyces sp. FJS31-2
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     GenBank staff is unable to verify sequence and/or annotation
            provided by the submitter.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 01:00:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15462
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..15462
                     /altitude="800 m"
                     /country="China: Fanjing Mountain, Guizhou province"
                     /db_xref="taxon:1840610"
                     /isolation_source="soil"
                     /lat_lon="27.50 N 108.67 E"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. FJS31-2"
                     /strain="FJS31-2"
     misc_feature    1..15462
                     /note="anthrabenzoxocinones biosynthetic gene cluster"
     protocluster    1..15462
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6164:8707]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="11|12 (Score: 667.8; E-value:
                     1e-203)"
                     /t2pks_molecular_weights="acetyl-CoA_11 (Da): 491.936"
                     /t2pks_molecular_weights="acetyl-CoA_12 (Da): 533.973"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      6165..8707
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="11|12 (Score: 667.8; E-value:
                     1e-203)"
                     /t2pks_molecular_weights="acetyl-CoA_11 (Da): 491.936"
                     /t2pks_molecular_weights="acetyl-CoA_12 (Da): 533.973"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..15462
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15462
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001366"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15462
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             11..274
                     /locus_tag="ctg1_orf1"
                     /transl_table=1
                     /translation="SGALEGRRGGGGPGGGADPLGPGRAVHQLGPLPVVAPRHGPARGG
                     PALDQGGVDGHTGALMERFAARGAPVQRSARLRERTASHRRRH"
     CDS             681..2492
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     567.4; E-value: 1e-171)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_orf2"
                     /transl_table=1
                     /translation="MRFQVLGNFEVLSDTRARTPSAPKLRRALALLILRHNEVVPTKAL
                     IDELWGSRPPDKAIRAVHTYIYELRRSLARPGGGGELFLQTRPSGYTVRVPESAIDLNS
                     FRVLVKEGREALAAGDPGHAREVLNRALGLWQGSALANVDCGELLEAHATELEESRLRA
                     LEMRIEADFQLSRHHELTGELKALAAARPLHEGIHAKLMLALYRSGRRGEALKVFHDLR
                     RHLVDELGLEPGPELQRLQRSMLAGDPSLDPPTAPPLPPPRRAQPPAPPAQLPRDTVDF
                     TGRQAVLDEVGALLAPHGDGTGLPVVSLVGMPGVGKTATAIHLAHAVRARYPDGQLYVP
                     LGGSQPTPATAAEGMEHILRGIGVAPRDIPSTLGGRMALFRTWSSDRRVLLVLDDADSP
                     QQVEPLLPGGTGCAVLITGRSLLYGLRGARTIALSCLSTAEGGQLLTRLIGRERTDAEP
                     EAVADVVRLADGLPLAITFLGERLMALRPVSIACVLAKIRSAKGQHRLSELSALGLDLY
                     DRLDSCFRKLDENTQQAFLRLALMPRRLFTAGQGARALGTDTTSADVVLMRLVDASLVE
                     VAGEREVGARHYRFRELVREYALERMA"
     CDS             2568..3191
                     /locus_tag="ctg1_orf3"
                     /transl_table=1
                     /translation="SGGVRGPVSGPQRG"
     CDS             3374..4846
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 433.5; E-value:
                     1.2e-131)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_orf4"
                     /transl_table=1
                     /translation="MDVTQDPAPPPRFWWAILVIAGAQLMVVLDISIVNIALPSIRDDL
                     GFTRSGLQWVVNGYTLAFGGLLLFGGRVGDLLGRRRVFACGVCAFALISLLGGFADGPG
                     RLIAARAAQGVAGALVAPTALALISTTFPEGRQRRAAFGVYGAVSAGGGAIGLLLGGLL
                     TDTLSWRWVLWVNVPIGAALACGALLVLPSSARRGGRFDLPGALSVTGGLTALVYGLVR
                     APQHGWADRWTLTSFAAAAGLLVLFVLIEVRGRQPLMPLRVFADRDRSGAYAVTLLTGA
                     ALLSTLFFLAQFAQDVMGYSPLRNGVAFLPNAACVLLFSGLAARLTARVGAMPLMAAGA
                     ASMALGLAWLSRLDVGARYAADLLPGLLLYGSGLGLLFVPLSMTAVATVADEDSGLASG
                     LLNTAQQVGGSLGLATLSTVAADSTRDALPAGRPPTRPQLAHALAEGWATALSVSVAFV
                     GCALVLVVAVIRARPRAAEPATRQEAVTRTPG"
     CDS             5011..5694
                     /locus_tag="ctg1_orf5"
                     /transl_table=1
                     /translation="MERVALGLPVGPGNETRVARLLRRLAPAQAGEVRTEAVATFTAPG
                     RVLHIADTTGGLDGLVADLTAHPDVAAGLRELCGMPHRLTVGSYLIRARLTRWAHYARP
                     YPARLPVHRRALLYPVRPGKGEELRRLLAAGIAPGTSQNLASALISSTVFARQDLVVRF
                     WEATADPAEELDNIARVVPRSGLGAKLNRLLDIEQDLTTDAGFRAFFTGCAMSPVPGAG
                     AWARP"
     CDS             5743..6168
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C18
                     (Score: 211.5; E-value: 7.8e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf6"
                     /transl_table=1
                     /translation="VTAQPVPVVSLDDALPNRRRGGDLRTLLSPKTVGATSGFLGVALI
                     EPGEYVAEHYHPYSEEFLYVVCGDLVVDLDGTPCELHADQGLMVPVGMRHRVRNTGAVQ
                     ARIVFHLSPLAPRPELGHVDTETVPSPATGTLAREGR"
     CDS             6165..7430
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-395). E-value:
                     6.8e-55. Score: 178.5. Matches aSDomain:
                     nrpspksdomains_ctg1_orf7_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 485.3; E-value:
                     2.7e-147)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     753.7; E-value: 1.2e-229)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_orf7"
                     /sec_met_domain="t2ks (E-value: 3.3e-233, bitscore: 764.1,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="VSRTAVITGIGVVAPGGVGTKGFWELLISGRTATRRISLFDPTGF
                     RSQVAAECDFDPAAEGLSPQEIRRMDRAAQFAVAAVREALADSGLTPAEAPAHRTGVSL
                     GSAVGCTTGLEEEYVVLSDGGRLHLVDHRYKVPELYGYMVPSTLAVETAWACGAEGPVG
                     LISTGCTSGLDAVGYGAQLIAEGSADVMVAGATDAPISPITSACFAAIKATSPNNDDPA
                     HASRPFDRLRDGFVLGEGAAVMVLEERGRAEARGAHVYAELAAFASRSNAFHMTGLRPD
                     GREMAEAIRVALDRARLAPGDVDYINAHGSGTRQNDRHETAAFKRALGERAREVPVSSI
                     KSMVGHSLGAIGAIEVAACALALEHQVVPPTANLHHPDPECDLDYVPLTARDHTMDVVL
                     SVGSGFGGFQTAMLLSRPGRAR"
     aSDomain        6183..7349
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_orf7_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.80E-55"
                     /label="ctg1_orf7_PKS_KS.1"
                     /locus_tag="ctg1_orf7"
                     /protein_end="395"
                     /protein_start="6"
                     /score="178.5"
                     /tool="antismash"
                     /translation="ITGIGVVAPGGVGTKGFWELLISGRTATRRISLFDPTGFRSQVAA
                     ECDFDPAAEGLSPQEIRRMDRAAQFAVAAVREALADSGLTPAEAPAHRTGVSLGSAVGC
                     TTGLEEEYVVLSDGGRLHLVDHRYKVPELYGYMVPSTLAVETAWACGAEGPVGLISTGC
                     TSGLDAVGYGAQLIAEGSADVMVAGATDAPISPITSACFAAIKATSPNNDDPAHASRPF
                     DRLRDGFVLGEGAAVMVLEERGRAEARGAHVYAELAAFASRSNAFHMTGLRPDGREMAE
                     AIRVALDRARLAPGDVDYINAHGSGTRQNDRHETAAFKRALGERAREVPVSSIKSMVGH
                     SLGAIGAIEVAACALALEHQVVPPTANLHHPDPECDLDYVPLTARDHTM"
     CDS_motif       7194..7238
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_orf7_0001"
                     /evalue="8.90E-03"
                     /label="NRPS-te1"
                     /locus_tag="ctg1_orf7"
                     /protein_end="358"
                     /protein_start="343"
                     /score="8.7"
                     /tool="antismash"
                     /translation="VGHSLGAIGAIEVAA"
     CDS             7427..8707
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (16-421). E-value:
                     2.1e-19. Score: 61.5. Matches aSDomain:
                     nrpspksdomains_ctg1_orf8_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 622; E-value:
                     6.1e-189)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 11|12
                     (Score: 667.8; E-value: 1e-203)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_orf8"
                     /sec_met_domain="t2clf (E-value: 1.6e-186, bitscore: 609.9,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="VTPAAGPATRTATAVITGLGIVAPGGIGVDEYWSAMLRGHSAIGP
                     ITRFDASGYPVRLAGEVSGFRTEERIPSRLAVQTDRWTHLGLAAAEAALADAGAGPGTL
                     TERPQQFGLSEYDMAVVTASSSGGTEFGQREIERLWSRGPRHVGAYQSIAWFYAATTGQ
                     ISIRHGMRGPCGVIAAEQAGALDALAHARRVVRDGARLVVSGGTDASLCPYGLVAQLSS
                     GRLSTREDPARAYVPFDAGACGHLPGEGGAMLIVEDARSARRRGAAHAYGEIAGHAATF
                     DPPPGSGREPGLRRAVMNALIDARMAPEEIDVVFADAAAVPALDRAEADALAWVFEPYG
                     VPVTAPKTLTGRLYAGAALDVATALLAMRDDVIPPTAAGVTPHPDHRLDLVVGEPRPGP
                     VRAVLVAARGFGGMNAALVLRRTDPRG"
     aSDomain        7475..8689
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_orf8_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="2.10E-19"
                     /label="ctg1_orf8_PKS_KS.1"
                     /locus_tag="ctg1_orf8"
                     /protein_end="421"
                     /protein_start="16"
                     /score="61.5"
                     /tool="antismash"
                     /translation="TGLGIVAPGGIGVDEYWSAMLRGHSAIGPITRFDASGYPVRLAGE
                     VSGFRTEERIPSRLAVQTDRWTHLGLAAAEAALADAGAGPGTLTERPQQFGLSEYDMAV
                     VTASSSGGTEFGQREIERLWSRGPRHVGAYQSIAWFYAATTGQISIRHGMRGPCGVIAA
                     EQAGALDALAHARRVVRDGARLVVSGGTDASLCPYGLVAQLSSGRLSTREDPARAYVPF
                     DAGACGHLPGEGGAMLIVEDARSARRRGAAHAYGEIAGHAATFDPPPGSGREPGLRRAV
                     MNALIDARMAPEEIDVVFADAAAVPALDRAEADALAWVFEPYGVPVTAPKTLTGRLYAG
                     AALDVATALLAMRDDVIPPTAAGVTPHPDHRLDLVVGEPRPGPVRAVLVAARGFGGMNA
                     ALVLRR"
     CDS             8725..8982
                     /NRPS_PKS="Domain: ACP (29-75). E-value: 3.5e-13. Score:
                     41.5. Matches aSDomain: nrpspksdomains_ctg1_orf9_ACP.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 107.9; E-value:
                     3.2e-33)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 110.7; E-value: 6.1e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf9"
                     /sec_met_domain="PP-binding (E-value: 5.5e-13, bitscore:
                     39.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTEFTIDDLRRIMRGSAGAQDGERIDGENLDADFADLGYDSLAVL
                     EIQSQIENTFDLTLPDDALSRMRTPRQTVSVVNACIGKEE"
     aSDomain        8812..8949
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_orf9_ACP.1"
                     /evalue="3.50E-13"
                     /label="ctg1_orf9_ACP.1"
                     /locus_tag="ctg1_orf9"
                     /protein_end="75"
                     /protein_start="29"
                     /score="41.5"
                     /tool="antismash"
                     /translation="LDADFADLGYDSLAVLEIQSQIENTFDLTLPDDALSRMRTPRQTV
                     S"
     CDS             8991..9494
                     /NRPS_PKS="Domain: Polyketide_cyc2 (17-159). E-value:
                     1.9e-18. Score: 59.0. Matches aSDomain:
                     nrpspksdomains_ctg1_orf10_Polyketide_cyc2.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 204.9; E-value: 3e-62)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C9-C14
                     (Score: 249.7; E-value: 1.8e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf10"
                     /transl_table=1
                     /translation="MTEATEATTATEPTEHARTDNSIVIDAPLELVWDITNDVENWPRL
                     FSEYETAEILHRDGDTIRFRLTMHPDENGTSWSWVSERTADPATHTVRSRRVETGPFAF
                     MDIFWEFTPEPEGVRMRWVQEFHMSPQAPADDAAMTAHINRNTRIQMALIRDRIEARAR
                     AAAS"
     aSDomain        9042..9467
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_orf10_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.90E-18"
                     /label="ctg1_orf10_Polyketide_cyc2.1"
                     /locus_tag="ctg1_orf10"
                     /protein_end="159"
                     /protein_start="17"
                     /score="59.0"
                     /tool="antismash"
                     /translation="RTDNSIVIDAPLELVWDITNDVENWPRLFSEYETAEILHRDGDTI
                     RFRLTMHPDENGTSWSWVSERTADPATHTVRSRRVETGPFAFMDIFWEFTPEPEGVRMR
                     WVQEFHMSPQAPADDAAMTAHINRNTRIQMALIRDRIE"
     CDS             9541..9882
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 111.7;
                     E-value: 2.7e-34)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C21/C2-C23|C2-C19 (Score: 128.1; E-value: 3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf11"
                     /transl_table=1
                     /translation="MATTLIVARLKPGDHHAAISSLFAESDATELPDLVGVQERRLLTF
                     QDLYFHLVRTDEALSKTLTPQHDNPLFRSISQAMDEYVTPYEGAWGSVQEASARQFYHW
                     KRGIGQVQS"
     CDS             9901..11211
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 394.5; E-value: 1.1e-119)"
                     /gene_functions="biosynthetic-additional (t2pks) HAL
                     (Score: 401.5; E-value: 1e-122)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf12"
                     /sec_met_domain="Trp_halogenase (E-value: 3.4e-29,
                     bitscore: 92.0, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="VTHSMDTTDTGDPGTSYDVVVIGGGPAGSSTAAQLARAGHRVLVL
                     EREKFPRYHIGESLIPGCLDLVRDLGLWDRLEGLGFTKKYGGTLLWGATEGTWDFRFAD
                     GSDYEYSFQVRRADFDALLLTRARELGARVVEEATVKDVEFDGDRATGLVYTVKGSDEP
                     VRVSSRFLVDASGQQRLLGRRLGLVDWHEDLRNVAVWSYFQGCDFIEGENRAGDVVVEN
                     MWQEDQPPGWFWFIPLHDGTVSIGYVTRTALLQRSGLTPDQLFEQQLAASDEVKRLTRN
                     ATRTSAYRTLRDWSYECTRFHGPGWAVVGDAAAFVDPLFSTGVTLAMRGARDLAPAVDQ
                     ALRDPGQEADLLKAYEDGYREFLGHVLTFVRFFYNIKMHKEQYWEGAQTIVDPQKLQAP
                     KIDFAVLLAGMTGIRPTPEMQADARAKTNDIHSRFAT"
     CDS             11019..11489
                     /locus_tag="ctg1_orf13"
                     /transl_table=1
                     /translation="LQHQDAQGTVLGGRPDHRRPAEAPGAEDRLRGPAGRHDRHPAHAR
                     DAGGRQGQDQRHPLPLRDMKTAMPVEELLPALAAIVLVARGVHALARRCRQPAVVAELA
                     AGILLGLALTDEAQAEILTRPVREGLTALGGLGLLLFLFETGCGADGGPAPRH"
     CDS             11554..12585
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 278.1; E-value:
                     1.8e-84)"
                     /gene_functions="biosynthetic-additional (t2pks) MET C6|C8
                     (Score: 461.3; E-value: 3.6e-141)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf14"
                     /transl_table=1
                     /translation="VTDTDYTPELATAARVKELAMGLWVSAMMMTAVQLRIPDEIDDKP
                     VEAGELAARLDLHPEALARLLRALAAHGVFTEVAEDRFGHTELSRVLREDHPNSVRYQV
                     LWTVAPWTWQAWPHLGEAVRTGERVFPRLYGKEFFAYLSQDAPQSAEVFNRAMTQSSAF
                     TSAMVAEALDMTGVRVVVDVGGGRGHLLRTVLERYPWLSGVLYDLAPVVASADPALRPG
                     GELADRAKVVAGSCLDGVPPGDLHILKNLLEWDDERTVTTLRHVAGALRSGGRAVLVQN
                     LVDDSPEPKVTTGMDLLLLLNVGGRKHTRRQLTRLLSEAGLEITEIRPTASSLFVIEIA
                     LRG"
     CDS             12582..14057
                     /locus_tag="ctg1_orf15"
                     /transl_table=1
                     /translation="LARPAPGPVRAVALPVRTVEGDRGQELADERAVPPRAGGPQLTPG
                     REAVQEQAGADVSRRRVGEGAHPQQLQRRRVALQQLGDQRAEPGPGVGRRDPGEPHHPV
                     EAQVVRGELARHPAHIAGLAPELVLLPHRVRRGQRLVGALDHHLEPGAVDAAEGAVGVD
                     QVQRIEGVVHQLTARHQVPGGPVAEHHHQSGGSQHQGLEPHRGTGERRRLGQSQRLGRE
                     PPVDRGEGQHDGHPVQPREVAGRDQPQLGDHDHGPGHACPRLRREQREGHDQLGDVVGR
                     HLDPVQGPRQPVEEPAQRARHRLCLVVVVQTGQLPPAAVAPDLDQPGAELDPEQQPAQQ
                     PQHQDRRGGTGVAEEDGEEAALQQQGLPAEPVPHLPHVDDRQIQQPQHQPHQHRGPQRH
                     PVRGPRHHRGGERGPQPGAAGEEAVREVEVEEARGAPERHPRGEPRHRRQAPLADQGPP
                     LVRRDHKGDQIEGRQAALEDQSAQPVVG"
     CDS             14222..15268
                     /locus_tag="ctg1_orf16"
                     /transl_table=1
                     /translation="SGPPWRGGAAARGERRGGRLVGAGRRLAEHIEQAAGDLGPEAEDV
                     MAHRRQRGAGELAQLGVVPGQQRDVDRNRKTHLGGHRQARHRHDVVVVDDRRRPVGRGQ
                     QRPRGARPLLTREVGGDRAPVGQPQFPYGRLEGGGTDHAVPQRGGAAHPGDPPVAQRRQ
                     IAHRLRDSGAVVGPYTGEAPGQGRVPGGHGGHPEPAQLGDARIPVVEVDENRPADLPPP
                     PPRLLDRDLLPHVPHQPQQQRAGPLDEHALDARDELHEPRLQPQHPGRPGDGQAHGVHP
                     RVGQRPGGEMGRPAQLPGGLEDPGPGGLGDARAVVEGERDRALGDPGPRGDVLDGDAPR
                     WPRRDLAVH"
ORIGIN
        1 cgacgccggg tcaggagcgc ttgaggggcg ccggggaggt ggcgggccgg gaggcggagc
       61 ggacccgctc gggccagggc gggcagttca ccagctcggc ccactcccgg tcgtagcgcc
      121 ccggcacggc ccggcccgcg gaggcccagc gctcgaccag ggcggcgtag atgggcacac
      181 aggtgctttg atggagcgtt tcgccgcccg cggtgctccg gtccagcgct ctgctcggct
      241 gcgagagaga acggcgtcgc atcgtcgtcg tcatgtcagg ccaacgcgcc gcgtccggtg
      301 cggtcaccgg cttcccgcgg agctcacccg gaccggggtg gtctcgcacg tatcatcgac
      361 cgcgcccgaa agtgaaaagc actgccgaat tcagaaagta ttccgtatcg ctgcaggccc
      421 tggttcacaa actccgattc acaaatggat acgtcgaact gatcagcgat ttgcggcggg
      481 taggggcggt ctcggttccg gtctcctggg tgcgtgctgc tcatgaatcg attcgcgtat
      541 cagcaggcac agatgcgatt gagccgaaat atggtgcgga tctactgatc atgcaggccg
      601 gaggtatgct cggctgcgac ctgaatacgg gggagcgggc ggggccttgt ggcaccacaa
      661 cgagccgggg gagttcgcga atgaggtttc aggttctggg aaacttcgaa gtcctgagcg
      721 acacccgcgc ccggacgccg agcgctccca agctccgccg ggccctggcc ctgctgatac
      781 tgcggcacaa cgaggtcgtg cccaccaagg ccctcatcga cgaactctgg ggaagccggc
      841 ccccggacaa agccattcgg gctgtacaca cctacatcta tgaactccgc cgcagcctgg
      901 cccgcccggg cggtggcgga gagctgttcc tccagacccg gccgagcggc tataccgttc
      961 gcgtaccgga aagcgcgatc gacctcaatt cctttcgagt cctggtcaaa gagggcaggg
     1021 aggcgcttgc tgcgggggac ccgggacacg cccgggaagt gctgaaccgg gccctggggc
     1081 tgtggcaggg cagcgccctg gccaatgtgg actgcgggga actgctcgaa gcgcatgcga
     1141 ccgagctgga ggagagccgg ctgcgtgccc tggagatgcg catcgaagcc gatttccaac
     1201 tcagccggca ccatgaattg accggtgagc tcaaggcgct ggccgccgcc aggcccctgc
     1261 acgagggcat ccacgccaaa ctgatgctcg cgctctaccg ttcggggcgg cgcggcgagg
     1321 cgctcaaggt cttccacgac ctgcgccgcc atctggtcga cgagctgggc ctggagccgg
     1381 gccccgagct ccagcggctg cagcgctcca tgctcgccgg ggacccctcg ctcgacccgc
     1441 cgaccgcgcc accgctcccg ccgccccgcc gcgcgcagcc cccggcaccg cccgcccagc
     1501 tcccccggga caccgtcgac ttcaccgggc ggcaggccgt gctcgacgag gtcggcgccc
     1561 tgctcgcgcc ccacggcgac ggcacgggcc tgcccgtggt gtcgctggtc ggcatgccgg
     1621 gcgtcggcaa gacggccacc gccatccacc tcgcccacgc ggtccgcgcc cgctaccccg
     1681 acgggcagct gtacgtaccg ctgggcggat cgcagcccac tccggcgacc gcggcggagg
     1741 ggatggaaca cattctgcgg gggatcggtg tggcgccgcg cgacatcccg agcacgctgg
     1801 gcgggcggat ggccctgttc cgcacctgga gctccgaccg ccgggtgctg ctggtactgg
     1861 acgacgccga ctcgccgcag caggtcgaac cgctgctccc gggcggcacc ggctgcgccg
     1921 tgctgatcac cggccgctcc ctgctgtacg ggctgcgcgg ggcgcggacc atcgcgctga
     1981 gctgcctgtc caccgcggag ggcgggcagc tgctcacccg gctgatcggg cgggagcgga
     2041 cggacgccga gcccgaggcc gtcgccgatg tggtgcggct ggcggacggt ctgccgctgg
     2101 ccatcacctt cctcggcgag cggctgatgg cgttgcggcc ggtcagtatc gcctgcgtgc
     2161 tggcgaagat acgatccgcc aaggggcagc accggctctc cgagctctcg gcgctggggc
     2221 tcgacctgta cgaccggctg gacagctgct tccgcaagct cgacgagaac acgcagcagg
     2281 cctttctgcg gctggccctg atgccgcgcc ggctgttcac cgccgggcag ggcgcccgtg
     2341 cgctgggcac cgacaccacc tcggccgacg tggtgctcat gcggctggtc gacgcctcac
     2401 tggtggaggt cgcgggggag cgggaggtgg gcgcgagaca ctaccgcttc cgggaactgg
     2461 tccgcgagta cgcgctggag cggatggcgt gacccgtacg gcgcccgcgg cgcgccactt
     2521 cacgggcttg tgcgcccgct gcgcccggat ggccgtgggc cgcgcgttca ggtggtgtcc
     2581 gcggcccggt gtccggcccg cagcgcgggt agcaccacct ggtcgaccat ggcctcgatg
     2641 gcccggtcgt ccggcggggt gccgttgagc agatagtgca tcatcacctg cgcgggcccg
     2701 gtccgcgcgg cgaacgggcc ggccgactcc ccggggatct cgccgcgctc ggccgcccgc
     2761 cgcaggatct ccgcgatcgc ctccagccgc ggctcgatga accgggtgcg gaacaccgcg
     2821 atcagctcgg ggtggcgcag cagatccccc agcagcacca tcgcgggcgg gccggtgcgg
     2881 ccggtgagcg agtcggccat ccgccgcagc gccgccacca gttcctcgcg cagatcgccc
     2941 gtctcgggca gttcctcgct gggcagcagg acatgttcga aggcgtcgag cagcaggtcc
     3001 tgcggggtgc tccagcggcg gtacagcgcc gccttaccgg tgcgcgcccg ttccgcgacc
     3061 cccttgagcg tcagcctgcc gtagcccagt tcggcgcact cggcgatcgt cgccttgtag
     3121 atggcccgct ccagggccgc gcccctgcga cgggtccgta ccggcggcgc cggtgcttcc
     3181 tccgcgccca tccggccgcc ttcctcccgg caagcattgc ccccaaaagc cccgtcaagc
     3241 accttcgagc ccctttgcgg actctatcag cggggtctac cctgccgaat aaggaacaga
     3301 ttagtctact atccggccgg cggcgcatcg ctgcgccccc tcctcacgat gggcgaaaga
     3361 ggggcgaacg accatggacg tcacccagga ccccgccccg ccgccccggt tctggtgggc
     3421 cattctggtg atcgcgggag cgcagctgat ggtggtgctg gacatcagca tcgtgaacat
     3481 cgcgctgccc agcatccgcg acgacctcgg cttcacccgg tccgggctgc agtgggtggt
     3541 caacggctac accctcgcct tcggcgggct gctgctgttc ggcggccggg tgggcgatct
     3601 cctgggccgc cgccgggtgt tcgcctgcgg agtctgcgcg ttcgcactga tctccctgct
     3661 cggcggcttc gccgacgggc ccggccggct catcgccgcc cgcgccgccc agggcgtggc
     3721 cggcgccctc gtcgcgccca ccgccctggc gctgatcagc acgaccttcc cggaagggcg
     3781 gcagcgccgc gccgcgttcg gcgtctacgg ggcggtgtcc gcgggcggcg gggctatcgg
     3841 gctgctgctg ggcgggctgc tcaccgacac cctctcctgg cgctgggtgc tctgggtcaa
     3901 tgtgcccatc ggcgccgcgc tcgcctgtgg cgccctgctg gtgctgccct cctccgcgcg
     3961 ccggggcggc cggttcgacc tgcccggggc gctctcggtc accggcgggc tgaccgcgct
     4021 ggtgtacggg ctggtccgcg ccccccagca cggctgggcc gaccgctgga cgctgacctc
     4081 gttcgccgcg gcggccgggc tcctggtcct gttcgtgttg atcgaggtgc gcggccggca
     4141 gccgctgatg ccgttgcgcg tcttcgccga ccgcgaccgc tccggtgcct acgcggtgac
     4201 cctcctgacc ggcgcggcgc tgctgagcac gctcttcttc ctcgcccagt tcgcgcagga
     4261 cgtgatgggc tactcaccgc tgcgcaacgg cgtggcgttc ctgcccaacg ccgcctgcgt
     4321 gctgctcttc tccgggctcg ccgcacggct gaccgcccgc gtcggcgcca tgccgctgat
     4381 ggccgcgggc gccgcctcga tggccctcgg cctggcctgg ctgtcgcggc tcgacgtcgg
     4441 cgcgaggtac gccgccgacc tgctgccggg cctgctgctg tacgggtccg gcctcggcct
     4501 gctgttcgta ccgctgtcca tgaccgcggt cgcgaccgtc gcggacgagg actccggcct
     4561 cgcctccggg ctgctcaaca ccgcccagca ggtgggcggt tcgctgggcc tggccacgct
     4621 gagcaccgtg gcggccgact ccacccggga cgccctgccc gccggccgcc cgccgacccg
     4681 cccgcagctc gcccacgcgc tggccgaggg ctgggccacg gccctgtccg tcagcgtggc
     4741 cttcgtcggc tgcgcgctgg tcctcgtcgt ggccgtgatc cgcgcccggc cgcgcgccgc
     4801 cgagcccgcc acacggcagg aggcggtcac ccgcaccccg ggctgacccg ggccgatgcc
     4861 cgcccttgtg agaaacctgt ccgcttcctg agcgtcgatg tgcaggctcg ccgcatcggc
     4921 tctttccggt tccccggacg cgacccggcc ccgggccgcg atgagccgag cgccgcacac
     4981 acagccgcac acacaggggg agtggtacgg atggagcggg tcgcgctggg acttccggtc
     5041 ggaccgggca acgaaacgcg ggtggcacgg ctgctgcgcc gcctcgcccc ggcccaggcc
     5101 ggcgaggtgc gcaccgaggc ggtggcgacg ttcaccgcgc cgggccgggt gctgcacatc
     5161 gccgacacca cgggcggtct cgacggcctc gtcgccgacc tcaccgcgca cccggacgtc
     5221 gcggccgggc tgcgcgagct gtgcggcatg ccccaccggc tgacggtggg ctcgtatctc
     5281 atccgggcca ggctcacccg ctgggcccac tacgcccggc cgtaccccgc gcgcctcccg
     5341 gtgcaccgcc gcgccctgct ctacccggta cggccgggca agggcgagga actgcgccgt
     5401 ctgctggccg caggaatcgc ccccggcacc tcccagaatc tcgcgtccgc cctgatcagc
     5461 agcaccgtct tcgcccgcca ggacctcgtc gtccggttct gggaggccac cgcggacccg
     5521 gccgaggagc tcgacaacat cgcccgcgtc gtcccgcgtt ccggcctggg ggccaagctc
     5581 aaccggctcc tggacatcga gcaggacctg accaccgacg ccggattccg ggcgttcttc
     5641 acgggttgcg cgatgtcccc cgtccccggc gcgggcgcct gggcccggcc gtagccgcgc
     5701 cggcaccacc cacctcacca ccgtcacttc cgaggaggaa gcgtgaccgc acagcctgtc
     5761 cccgtcgtct cgctggacga cgccttgccc aaccgccggc gcggcgggga tctgcgcacc
     5821 ctgctcagcc ccaagacggt cggcgccacc tccggcttcc tcggcgtggc gctcatcgag
     5881 cccggcgaat acgtggccga gcactaccac ccctactccg aggagttcct gtacgtggtg
     5941 tgcggcgacc tcgtggtcga cctcgacggc acgccgtgcg aactccacgc cgaccagggg
     6001 ctgatggtcc cggtcgggat gcgccaccgc gtgcgcaaca ccggagccgt gcaggccagg
     6061 atcgtcttcc acctctcccc gctggccccg cgcccggaac tgggccatgt ggacaccgag
     6121 acggtcccct ccccggccac aggcacgctc gcccgggagg ggcggtgagt cgcaccgccg
     6181 tcatcaccgg gatcggggtg gtggcccccg gcggagtcgg caccaagggc ttttgggagc
     6241 tgctcatctc cgggcgcacc gccacccggc ggatctccct cttcgacccc accggattcc
     6301 gctcccaggt ggccgccgaa tgcgacttcg accccgccgc cgaaggactg agcccgcagg
     6361 agatacgccg gatggaccgg gccgcccagt tcgcggtcgc cgcggtgagg gaagcgctcg
     6421 ccgacagcgg gctgaccccc gccgaggcgc ccgcgcaccg caccggcgtg agcctgggca
     6481 gcgccgtcgg gtgcaccacg ggactggagg aggagtatgt cgtcctgagc gacggcggcc
     6541 ggctccacct ggtcgaccac cgctacaaag tccccgagct gtacgggtac atggtgccca
     6601 gcacgcttgc cgtcgagacg gcgtgggcgt gcggcgccga gggcccggtc ggcctgatct
     6661 ccaccggctg cacctcgggt ctcgacgccg tcggctacgg cgcccagctc atcgccgagg
     6721 gctcggccga cgtgatggtc gcgggcgcca ccgacgcgcc catctcgccc atcacctcgg
     6781 cctgcttcgc cgccatcaag gccacctcgc ccaacaacga cgacccggcc cacgcctccc
     6841 gccccttcga ccgcctgcgg gacggcttcg tccttggcga gggcgcggcc gtgatggtgc
     6901 tggaggagcg cggccgagcc gaggcccggg gcgctcatgt ctacgccgag ctcgcggcct
     6961 tcgcgagccg cagcaacgcc ttccacatga ccggactgcg ccccgacggc cgggagatgg
     7021 ccgaggccat ccgggtcgcc ctggaccggg cccgcctcgc gccgggcgat gtcgactaca
     7081 tcaacgcgca cggctccggc acccgccaga acgaccgcca cgaaaccgcc gccttcaagc
     7141 gcgcgctggg cgagcgggcc cgcgaggtgc ccgtcagctc catcaagtcc atggtcggcc
     7201 actcgctcgg ggcgatcggc gcgatcgagg tcgccgcctg cgcgctggcg ctggaacacc
     7261 aggtcgtgcc gcccaccgcc aatctgcacc accccgaccc cgaatgcgac ttggactacg
     7321 tcccgctgac ggcccgtgac cacaccatgg acgtggtgct ctcggtcggc agcggcttcg
     7381 gcggcttcca gacggcgatg ctgctcagcc ggcccgggag ggcccggtga cccccgcggc
     7441 cgggccggcc acgcgcaccg ccaccgccgt catcacgggt ctgggcatcg tcgcgccggg
     7501 cggcatcggc gtcgatgagt actggtcggc gatgctgcgc ggacacagtg ccatcggccc
     7561 catcacccgc ttcgacgcct ccggctatcc ggtgcggctg gccggcgagg tgtccggctt
     7621 ccgcaccgaa gagcgcatcc ccagcaggct ggccgtccag accgaccgct ggacccacct
     7681 tggcctggcc gccgcggagg ccgcgctcgc cgacgccggg gcgggcccgg gcaccctgac
     7741 ggaaagaccc cagcagttcg gactgtccga atacgacatg gcggtcgtga ccgcctcctc
     7801 ctccggcggc accgagttcg ggcagcggga gatcgaacgg ctgtggtcgc gcgggccccg
     7861 gcacgtcggc gcgtaccagt cgatcgcctg gttctacgcc gcgaccaccg gccagatttc
     7921 catccgccac ggcatgcgcg ggccgtgcgg ggtcatcgcg gccgagcagg ccggcgccct
     7981 ggacgcgctc gcgcacgccc gccgggtggt gcgcgacggc gcccggctcg tggtcagcgg
     8041 cggcaccgac gcctcgctgt gcccgtacgg tctcgtcgcc cagctctcca gcggccggct
     8101 gtccacccgc gaggacccgg cacgggccta tgtgcccttc gacgccgggg cctgcggcca
     8161 cctcccgggc gagggcgggg cgatgctgat cgtcgaggac gcccgctcgg cccggcggcg
     8221 cggcgccgcc cacgcgtacg gcgagatcgc cgggcacgcg gccaccttcg acccgccacc
     8281 cggctccggc cgtgagcccg ggttgcgccg cgccgtcatg aacgccctga tcgacgcccg
     8341 gatggcgccg gaggagatcg acgtcgtctt cgccgacgcc gccgccgtac ccgccctcga
     8401 ccgcgccgag gcggacgccc tcgcctgggt cttcgagccg tacggcgtgc ccgtcaccgc
     8461 gcccaagacg ctgaccggcc ggctctacgc gggcgccgcg ctggacgtgg ccaccgcgct
     8521 gctggccatg cgcgacgacg tcatcccgcc caccgcggcc ggggtgaccc cgcaccccga
     8581 ccaccggctc gacctggtgg tgggcgagcc gcggcccggc cccgtacggg cggtcctggt
     8641 ggccgcccgg ggcttcggcg gcatgaacgc cgcgctggtc ctgcgccgga cggacccgcg
     8701 cggatgaacg agcaaggaga cgccatgacc gaattcacca tcgacgacct gaggcggatc
     8761 atgcgcggca gcgcgggggc ccaggacggg gagcgcatcg acggggagaa cctcgacgcc
     8821 gacttcgccg acctcggcta cgactcgctg gccgtactgg agatccagtc gcagatcgag
     8881 aacaccttcg acctgacgct gcccgacgac gccctcagtc ggatgcgcac cccacggcag
     8941 accgtctccg tggtcaacgc ctgtatcgga aaagaggagt gagccggctc atgaccgaag
     9001 cgaccgaagc gaccacagcg actgaaccga ctgagcatgc ccgcaccgac aactccatcg
     9061 tcatcgacgc gcccctggag ctggtctggg acatcacgaa cgacgtcgag aactggccgc
     9121 ggctgttcag cgagtacgag acggccgaga tcctccaccg ggacggcgac accatacggt
     9181 tccgcctcac catgcacccg gacgagaacg gcaccagctg gagctgggtg tccgagcgca
     9241 ccgcggaccc ggccacccat accgtccgct cccgccgcgt cgagacgggc cccttcgcat
     9301 tcatggacat cttctgggag ttcaccccgg agcccgaagg ggtgcgcatg cgctgggtcc
     9361 aggagttcca catgtcgccc caggcccccg ccgacgacgc cgccatgacc gcgcacatca
     9421 accgcaacac caggatccag atggcgctga tccgcgaccg gatcgaggcc cgcgcccgcg
     9481 cggcggcctc ctgagccggc cctgtcccga ccaccgcacc accacaccga ggagattccc
     9541 atggccacga ccttgatcgt cgcccggctg aagcccggcg accaccacgc cgcgatcagc
     9601 agcctgttcg cggagtcgga cgccaccgaa ctgcccgacc tggtgggcgt ccaggagcgg
     9661 cggctgctga ccttccagga cctgtacttc cacctcgtcc gcacggacga ggccctctcc
     9721 aagaccctca ccccgcaaca cgacaatccg ctgttccggt cgatcagcca ggcgatggac
     9781 gagtacgtca ccccgtacga gggcgcctgg ggcagcgtcc aggaggcctc ggcccggcag
     9841 ttctaccact ggaagcgcgg catcggccag gtccagtcct gacggttcgg agggaacacc
     9901 gtgacacact caatggacac gacagacaca ggcgaccccg gtacctccta cgacgtcgtt
     9961 gtgatcggcg gcggccccgc cggctcgagc accgcggccc agctggcccg ggccggccac
    10021 cgggtgctgg tgctggagcg ggagaagttc ccccgctacc acatcggcga gtccctcatc
    10081 cccggctgcc tcgacctggt cagggacctg ggcctgtggg accggctgga aggcctcggc
    10141 ttcaccaaga agtacggcgg caccctgctg tggggcgcca ccgagggcac ctgggacttc
    10201 cggttcgccg acggcagcga ctacgagtac tccttccagg tgcgccgcgc cgacttcgac
    10261 gccctgctgc tcacccgcgc ccgggagctc ggcgcccggg tggtcgagga ggccacggtc
    10321 aaggacgtgg agttcgacgg cgaccgcgcc accggcctgg tctacaccgt caagggctcg
    10381 gacgagcccg tacgggtctc ctcccgcttc ctcgtcgacg cctccggaca gcagcggctc
    10441 ctcggccgcc ggctcgggct cgtcgactgg cacgaggacc tgcgcaatgt cgcggtgtgg
    10501 agctacttcc agggctgcga cttcatcgag ggcgagaacc gggccggcga cgtggtcgtg
    10561 gagaacatgt ggcaggagga ccagcctccc ggctggttct ggttcatccc gctgcacgac
    10621 ggcacggtca gcatcggcta tgtcacccgc accgctctgc tgcagcgctc cggtctgacc
    10681 ccggaccagc tgttcgaaca gcagctggcc gcctcggacg aggtcaagcg gctcacccgg
    10741 aacgccacca ggaccagcgc ctaccgcacc ctgcgcgact ggagctatga gtgcacccgc
    10801 ttccatggcc ccggctgggc cgtggtcggc gacgccgcgg cctttgtcga cccgctgttc
    10861 tccaccggcg tcaccctggc catgcgcggt gcgcgggacc tggcccccgc ggtcgaccag
    10921 gcgctgcgcg acccgggcca ggaggccgat ctgctcaagg cgtacgagga cgggtaccgc
    10981 gaattcctcg gccacgtcct gaccttcgtg cgcttcttct acaacatcaa gatgcacaag
    11041 gaacagtact gggagggcgc ccagaccatc gtcgacccgc agaagctcca ggcgccgaag
    11101 atcgacttcg cggtcctgct ggccggcatg accggcatcc ggcccacgcc cgagatgcag
    11161 gcggacgcca gggccaagac caacgacatc cactcccgct tcgcgacatg aagaccgcca
    11221 tgccggtgga ggagctgctg ccggccctcg cggcgatcgt cctcgtcgca cggggcgtcc
    11281 acgccctggc ccggcgctgc cgccagccgg cggtcgtggc cgagctggcc gcgggcatcc
    11341 tcctcggcct ggcgctcacc gacgaggcac aggccgagat cctcacccgc ccggtgcgcg
    11401 aggggctcac cgcgctcggc ggcctcggcc tgctgctgtt cctcttcgag acggggtgcg
    11461 gggccgatgg cggcccggcg ccccggcacg gccggcgggc accggcgacg gcccggccgc
    11521 ggccccccaa ccctcacgag aggcggaaac actgtgaccg acaccgacta cacccccgag
    11581 ctggcgaccg cggcccgggt gaaggaactg gcgatgggcc tgtgggtctc cgccatgatg
    11641 atgacggccg ttcagctgcg gatccccgac gagatcgatg acaagccggt cgaggcgggc
    11701 gagctcgccg cccggctgga cctgcacccc gaggccctcg cccggttgct gcgggcgctg
    11761 gccgcgcacg gcgtcttcac ggaggtggcc gaggaccgtt tcggacacac cgagctctcc
    11821 cgggtgctcc gcgaggacca cccgaacagc gtgcgctacc aggtgctgtg gaccgtggcc
    11881 ccctggacct ggcaggcctg gccgcacctg ggggaggcgg tgcgcaccgg cgagcgggtc
    11941 ttcccgcgcc tgtacggcaa ggagttcttc gcctatctct cccaggacgc cccgcagtcc
    12001 gccgaggtgt tcaaccgggc catgacccag tcctccgcct tcacctcggc catggtcgcc
    12061 gaggccctgg acatgaccgg cgtacgcgtc gtggtcgacg tcggcggcgg ccgcggccac
    12121 ctgctgcgca ccgtcctgga gcggtacccc tggctgagcg gggtgctcta cgacctggcg
    12181 cccgtggtgg cctccgcgga ccccgccctg cggcccggcg gcgaactcgc cgaccgcgcc
    12241 aaggtggtcg cgggcagctg cctggacggc gtcccgcccg gcgacctcca catcctgaag
    12301 aacctgctgg aatgggacga cgaacggacc gtcaccacgc tgcggcacgt ggccggggcg
    12361 ctgcgctcgg gcggccgggc ggtgctggtg cagaacctgg tcgacgacag ccccgagccc
    12421 aaggtcacca ccgggatgga tctgctgctg ctcctcaacg tcggcgggag gaagcacacc
    12481 aggcgccagc tgacccggct gctgtccgag gcgggccttg agatcaccga gatccgtccc
    12541 acggccagca gcctcttcgt catcgaaatc gccctgcgcg gctagcccgt cccgccccgg
    12601 gtcccgtccg ggcggtcgcc ctgccggtcc ggacggtcga gggcgaccgg gggcaggaac
    12661 tcgcggatga gcgtgcggtg ccaccacgcg ccggtggccc gcaactcact ccaggtcgtg
    12721 aagcggtaca ggaacaggcg ggcgcggatg taagcaggcg gcgcgtcggg gaaggggcac
    12781 acccgcaaca gcttcagcgt cgccgggtcg ccctccagca gcttggtgac cagcgggccg
    12841 aaccaggacc gggcgtaggc cggcgagatc ccggcgaacc acatcatcca gtcgaggcgc
    12901 aggtggtacg gggcgaactg gcgcggcatc cggcgcacat cgccgggctt gccccggaac
    12961 tcgtactcct tccacaccgt gtccgacgtg ggcagcggct cgtcggtgcc ctggatcacc
    13021 acctcgaacc gggcgcggtt gacgctgccg aaggcgccgt aggtgttgac caggtgcagc
    13081 ggattgaagg agtagttcat cagctgactg cccgacacca ggttccgggc gggccagtag
    13141 ctgagcacca ccaccagagc ggtggcagcc agcaccaggg cctcgaacca caccggggga
    13201 ccggcgagcg gcggcggctc gggcagtccc agcgcctggg ccgcgagccg cccgtcgacc
    13261 gcggcgaggg ccagcacgat ggtcacccag ttcagccacg agaagttgcc ggacgcgacc
    13321 agccacagct gggtgaccac gatcacggcc ccggccacgc ttgcccccgg ctgcggcgcg
    13381 aacagcgcga ggggcacgac caattgggcg acgtggttgg ccgccacctc gacccggtgc
    13441 aagggccccg gcagccggtg gaagaaccag ctcagcgggc ccggcatcgg ctgtgtctcg
    13501 tggtggtagt acagacaggt cagctgccgc cagcagcggt cgccccggat cttgatcagc
    13561 ccggcgccga actcgacccg gaacagcagc cagcgcagca gccacagcac caggaccggc
    13621 ggggcggtac gggcgttgcc gaggaagacg gcgaggaagc cgctctccag cagcagggac
    13681 tcccagccga acccgtacca cacctgcccc acgttgacga tcgacagata cagcagccac
    13741 agcaccagcc acatcagcat cgcggcccac agcggcaccc ggtccgcggc ccccgccacc
    13801 accgcggcgg cgagcgcggc ccccagccag gcgcagccgg tgaagaagcg gtccgagaag
    13861 tggaggtgga agaggctcgg ggagcgccgg aacggcatcc gcgcggtgaa ccgcggcacc
    13921 ggcgtcaggc cccgctcgcc gatcagggcc cgcccctggt tcgccgcgac cacaaaggcg
    13981 atcagataga gggccgccag gccgcgttgg aagaccagtc ggctcagcca gtagtcggat
    14041 gaggtgaacc actccatgcg gaaccgctcc ctgggcctgt ttcccggctc ggttcgccct
    14101 tgccgccggg cactcggcta tccgtaccac ctaccgttaa acgcgtgcgg cccggcgggc
    14161 cccggggccg gccgagttca tccggtcggc gcgcccggcc gccggtcctc gcttaaccgg
    14221 ttcagggccg ccgtggcggg gcggtgctgc cgcgcggggt gagcgccggg gtgggcgcct
    14281 ggtgggtgct gggcgccgcc tggccgagca catcgaacag gcggcgggcg acctcggccc
    14341 cgaagccgaa gacgtcatgg ctcatcgccg acagcgtggg gcgggtgagc tggcacagct
    14401 gggagtcgtc ccaggccagc agcgagacgt cgaccggaac cgcaagaccc atctcggcgg
    14461 tcaccgacag gcccgccacc gccatgatgt cgttgtcgta gatgaccgcc gtcggccggt
    14521 cggccgaggc cagcagcgcc cgcgtggcgc gcgccccctc ctcacccgag aagtcggtgg
    14581 cgaccgtgcg cccgtcggcc agccccagtt cccgtacggc cgcctcgaag gcggcggtac
    14641 ggatcacgct gtgccccagc gtggcggggc cgctcacccg ggcgatccgc cggtggccca
    14701 gcgccgccag atagcgcacc gcctccgtga cagcggtgcc gtcgtcggtc catacacagg
    14761 tgaagccccc ggccagggac gggtgcccgg cggccacggc gggcaccccg agccggcgca
    14821 gctcggggac gcgcggatcc ccgtcgtgga ggtcgacgag aatcgacccg ccgacctgcc
    14881 gcccccgcca ccacgcctcc tggaccgcga tctcctcccg cacgtcccgc accagccgca
    14941 gcagcagcga gcaggaccgc tcgacgagca cgctctcgat gcccgagacg aactccatga
    15001 accacggctc cagccccagc atccgggccg gccgggcgat ggccaggccc acggcgtcca
    15061 cccgcgcgtt ggacagcgac cgggcggaga gatggggcgc ccagcccagc tcccgggcgg
    15121 cctcgaagat ccgggcccgg gtggcctggg agacgcccgg gcggtcgttg aaggcgagcg
    15181 agaccgcgcc cttggagacc ccggcccgcg cggcgacgtc cttgatggtg acgcgccgcg
    15241 gtggccccgc cgtgacctcg ctgtccatgc accgactccc gctgctcggc tgccgctcgc
    15301 gacgaacgcc acaccctacc gcgtcggtaa accggtcaag gtcgcttttc gcgtgcgcag
    15361 cgccgcgaac agccgcgggc cgaaccgttc gcgggcccct cacccgctcc gccggtacgc
    15421 cgacggagcc ggggaggggc cgcggccgag gacctggccg ag
//
