BGC0001369 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001369 (uncultured bacterium)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	HR-T2PKS	1	30,926	metatricycloene	PKS	100%

BGC0001369 - Region 1 - HR-T2PKS

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Location: 1 - 30,926 nt. (total: 30,926 nt) Show pHMM detection rules used

Region on contig edge.

HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 30,927
Label		BGC0001369

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001369	0.95	Polyketide	metatricycloene	uncultured bacterium
BGC0002031	0.32	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0002218	0.29	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0001529	0.27	Alkaloid	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0000844	0.26	Other	clavulanic acid	Streptomyces clavuligerus
BGC0000196	0.26	Polyketide	AQ-256, AQ-270a, AQ-284a	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002474	0.25	NRP	agrobactin	Agrobacterium tumefaciens
BGC0000937	0.25	Other	fosfazinomycin A, fosfazinomycin B	Streptomyces sp. WM6372
BGC0000812	0.25	Alkaloid	huperzine A	Shiraia sp. slf14
BGC0001264	0.24	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001369	0.98	Polyketide	metatricycloene	uncultured bacterium
BGC0002031	0.65	Alkaloid	kitasetaline	Kitasatospora setae KM-6054
BGC0002218	0.63	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0001529	0.61	Alkaloid	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0000844	0.60	Other	clavulanic acid	Streptomyces clavuligerus
BGC0000196	0.59	Polyketide	AQ-256, AQ-270a, AQ-284a	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002474	0.59	NRP	agrobactin	Agrobacterium tumefaciens
BGC0000937	0.59	Other	fosfazinomycin A, fosfazinomycin B	Streptomyces sp. WM6372
BGC0000812	0.58	Alkaloid	huperzine A	Shiraia sp. slf14
BGC0001264	0.57	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae

Similar known gene clusters from MIBiG 4.0

NRPS/PKS substrates

NRPS/PKS substrate predictions

ANY57963.1

PKS_AT (4..296): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 61.3
Methoxymalonyl-CoA: 36.5
Methylmalonyl-CoA: 33.6
inactive: 24.5
Isobutyryl-CoA: 22.1
Propionyl-CoA: 14.6
CHC-CoA: 13.6
fatty_acid: 9.2
Ethylmalonyl-CoA: 7.9
trans-1,2-CPDA: 6.8
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: -1.7