Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001378.1:
Cluster 1Polyketide149994

BGC0001378, tiancimycin biosynthetic gene cluster from Streptomyces sp. CB03234. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: tiancimycin

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Modular Type I

Gene cluster description

tiancimycin (BGC0001378). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank KT716443. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Ge HM et al. (2014) Enediyne polyketide synthases stereoselectively reduce the beta-ketoacyl intermediates to beta-D-hydroxyacyl intermediates in enediyne core biosynthesis. Org Lett 16(15):3958-61. doi: 10.1021/ol501767v. Epub 2014 Jul 14.