BGC0001379 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001379 (Streptomyces luteocolor)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	33,575	BD-12	NRPS:Type I	100%

BGC0001379 - Region 1 - NRPS-like

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Location: 1 - 33,575 nt. (total: 33,575 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 33,576
Label		BGC0001379

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001379	0.90	NRP	BD-12	Streptomyces luteocolor
BGC0001206	0.32	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0000953	0.29	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0000900	0.28	Other	ferrichrome	Aspergillus oryzae
BGC0001249	0.27	NRP	dimethylcoprogen	Alternaria alternata
BGC0000348	0.26	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000327	0.25	NRP	netropsin	Streptomyces ambofaciens ATCC 23877
BGC0001517	0.24	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0000921	0.24	Other (Shikimate-derived), Polyketide, NRP	promysalin	Pseudomonas putida
BGC0002652	0.24	Other, Saccharide	cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E	Streptomyces sp. SHP22-7

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001379	1.00	NRP	BD-12	Streptomyces luteocolor
BGC0001206	0.66	Other	indolmycin	Streptomyces griseus subsp. griseus
BGC0000953	0.63	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0000900	0.61	Other	ferrichrome	Aspergillus oryzae
BGC0001249	0.61	NRP	dimethylcoprogen	Alternaria alternata
BGC0002710	0.60	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0000348	0.59	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001147	0.59	NRP	disgocidine, distamycin, congocidine	Streptomyces netropsis
BGC0002652	0.58	Other, Saccharide	cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E	Streptomyces sp. SHP22-7
BGC0000252	0.58	Polyketide	nonactin	Streptomyces griseus subsp. griseus

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 4171 - 33575:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

BAU50944.1

AMP-binding (17..417): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVEELGVVTK
Nearest Stachelhaus code(s):: Ahp DVENAGVVTK (50% 8Å match)
Stachelhaus code match:: 80% (moderate)