BGC0001384: saprolmycin E biosynthetic gene cluster from Streptomyces sp. TK08046
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Location: 1 - 44,148 nt. (total: 44,148 nt).
This entry is originally from NCBI GenBank LC131463.1.

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core biosynthetic genes
additional biosynthetic genes
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Gene details
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001384
Short description saprolmycin E biosynthetic gene cluster from Streptomyces sp. TK08046
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: LC131463.1
Compounds
  • saprolmycin E
Species Streptomyces sp. TK08046 [taxonomy]
References
Chemical products information
saprolmycin E
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C43H48O16
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAV16989.1
  • spr1
 2469 - 3950 (-) putative acyltransferase
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  • BAV16990.1
  • sprR1
 4092 - 4439 (-) putative transcriptional regulatory protein
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  • BAV16991.1
  • spr2
 4751 - 6217 (-) putative MFS transporter
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  • BAV16992.1
  • spr3
 6139 - 7257 (-) putative oxidoreductase
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  • BAV16993.1
  • spr4
 7365 - 8945 (-) putative transporter
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  • BAV16994.1
  • spr5
 8976 - 9575 (-) putative FMN reductase
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  • BAV16995.1
  • sprR2
 9694 - 10431 (+) putative tetR-family regulatory protein
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  • BAV16996.1
  • sprA
 10484 - 11413 (+) hypothetical protein
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  • BAV16997.1
  • sprB
 11762 - 13249 (+) putative oxygenase
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  • BAV16998.1
  • sprC
 13263 - 13589 (+) putative cyclase
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  • BAV16999.1
  • sprD
 13586 - 14866 (+) putative ketosynthase
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  • BAV17000.1
  • sprE
 14863 - 16107 (+) putative chain length determinant factor
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  • BAV17001.1
  • sprF
 16104 - 16478 (+) putative acyl carrier protein
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  • BAV17002.1
  • sprG
 16648 - 17433 (+) putative ketoreductase
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  • BAV17003.1
  • sprH
 17474 - 18409 (+) putative aromatase
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  • BAV17004.1
  • sprI
 18412 - 20400 (+) putative oxygenase-reductase
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  • BAV17005.1
  • sprJ
 20420 - 21631 (+) putative transporter
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  • BAV17006.1
  • sprGT1
 21689 - 22981 (+) putative O-glycosyltransferase
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  • BAV17007.1
  • sprGT2
 23009 - 24223 (+) putative O-glycosyltransferase
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  • BAV17008.1
  • sprK
 24220 - 24786 (+) putative NDP-hexose 3,5-epimerase
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  • BAV17009.1
  • sprGT3
 24789 - 25919 (+) putative C-glycosyltransferase
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  • BAV17010.1
  • sprL
 25945 - 27012 (+) dNDP-glucose synthase
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  • BAV17011.1
  • sprM
 27009 - 27992 (+) putative dTDP-glucose 4,6 dehydratase
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  • BAV17012.1
  • sprN
 28003 - 29106 (+) NDP-hexose 4-ketoreductase
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  • BAV17013.1
  • sprO
 29103 - 30413 (+) putative NDP-hexose dehydratase
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  • BAV17014.1
  • sprP
 30469 - 31233 (+) putative NDP-hexose 4-ketoreductase
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  • BAV17015.1
  • sprQ
 31282 - 32364 (+) hypothetical protein
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  • BAV17016.1
  • sprR
 32459 - 33859 (+) putative NDP-hexose 2,3-dehydratase
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  • BAV17017.1
  • sprS
 33856 - 34812 (+) putative NDP-hexose 3-ketoreductase
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  • BAV17018.1
  • sprT
 34809 - 35573 (+) putative phosphopantetheine transferase
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  • BAV17019.1
  • sprU
 35587 - 37179 (+) putative methylmalonyl-CoA carboxyltransferase
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  • BAV17020.1
  • sprX
 37219 - 37902 (+) putative oxidoreductase
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  • BAV17021.1
  • sprY
 38025 - 39647 (+) putative FAD/FMN-containing dehydrogenase
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  • BAV17022.1
  • sprZ
 39764 - 40201 (+) hypothetical protein
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  • BAV17023.1
  • sprR3
 40793 - 41575 (-) putative transcriptional regulator
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  • BAV17024.1
  • spr6
 42116 - 44008 (+) putative oxidoreductase
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Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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