LOCUS       BGC0001386             25601 bp    DNA     linear   BCT 03-MAY-2016
DEFINITION  Streptomyces sp. RI-77 DNA, contains isofuranonaphthoquinone
            biosynthetic gene cluster.
ACCESSION   BGC0001386
VERSION     BGC0001386
KEYWORDS    .
SOURCE      Streptomyces sp. RI-77
  ORGANISM  Streptomyces sp. RI-77
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 01:10:33
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..25601
                     /db_xref="taxon:1799151"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. RI-77"
                     /strain="RI-77"
     misc_feature    1..25601
                     /note="isofuranonaphthoquinone biosynthetic gene cluster"
     protocluster    1..25601
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[13269:15782]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 724.9; E-value:
                     5.1e-221)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 322.353"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      13270..15782
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 724.9; E-value:
                     5.1e-221)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 322.353"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..25601
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..25601
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001386"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25601
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             194..937
                     /NRPS_PKS="Domain: PKS_KR (4-173). E-value: 7.7e-12. Score:
                     37.3. Matches aSDomain: nrpspksdomains_BAU98027.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     199.7; E-value: 9.4e-61)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     139.0; E-value: 5.2e-43)"
                     /gene_kind="biosynthetic-additional"
                     /note="orf1"
                     /product="dehydrogenase"
                     /protein_id="BAU98027.1"
                     /transl_table=11
                     /translation="MTDIALVTGANKGLGKEIARRLAAEGLTVYLGARDETRGRVAAGE
                     LRAAGLDVRFVRLDVTVREQVDAAVRTVDEECGRLDVLVNNAGIVTEWGLPVEDITEDH
                     LRRAFEVNVLGTVAVTRACLPLLRRSKDARVVNLSSPLGSLTLLDDPEHPAASRGLLAY
                     SSSKAALNAVTLVYAEALRDAGIRVNAANPGLVATDLNADSPFSRGTRTVEEGAEVPVR
                     LALGAGGTGGFHGSMEGDVAERVPW"
     aSDomain        206..712
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAU98027.1_PKS_KR.1"
                     /evalue="7.70E-12"
                     /label="BAU98027.1_PKS_KR.1"
                     /locus_tag="BAU98027.1"
                     /protein_end="173"
                     /protein_start="4"
                     /score="37.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGANKGLGKEIARRLAAEGLTVYLGARDETRGRVAAGELRAA
                     GLDVRFVRLDVTVREQVDAAVRTVDEECGRLDVLVNNAGIVTEWGLPVEDITEDHLRRA
                     FEVNVLGTVAVTRACLPLLRRSKDARVVNLSSPLGSLTLLDDPEHPAASRGLLAYSSSK
                     AALNAV"
     CDS_motif       209..271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BAU98027.1_0001"
                     /evalue="5.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BAU98027.1"
                     /protein_end="26"
                     /protein_start="5"
                     /score="15.9"
                     /tool="antismash"
                     /translation="LVTGANKGLGKEIARRLAAEG"
     gene            complement(1056..1346)
                     /gene="ifnA"
     CDS             complement(1056..1346)
                     /NRPS_PKS="Domain: PP-binding (35-86). E-value: 7.4e-14.
                     Score: 43.9. Matches aSDomain:
                     nrpspksdomains_ifnA_PP-binding.1"
                     /codon_start=1
                     /gene="ifnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 110.5; E-value:
                     5.3e-34)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 111.1; E-value: 4.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl carrier protein"
                     /protein_id="BAU98028.1"
                     /sec_met_domain="PP-binding (E-value: 3.4e-14, bitscore:
                     43.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPTEPEETTAMATVGIEDLRRILVACAGEEEGSRLGGDTLDTPF
                     EELGYDSLALMETAAAIQEEYGIVLPDEEVSEARTPRTLLDLANGAVRTGG"
     aSDomain        complement(1089..1241)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnA_PP-binding.1"
                     /evalue="7.40E-14"
                     /label="ifnA_PP-binding.1"
                     /locus_tag="ifnA"
                     /protein_end="86"
                     /protein_start="35"
                     /score="43.9"
                     /tool="antismash"
                     /translation="LGGDTLDTPFEELGYDSLALMETAAAIQEEYGIVLPDEEVSEART
                     PRTLLD"
     gene            1641..2633
                     /gene="ifnB"
     CDS             1641..2633
                     /codon_start=1
                     /gene="ifnB"
                     /product="dehydrogenase"
                     /protein_id="BAU98029.1"
                     /transl_table=11
                     /translation="MLSHATAALHVVVDAVGAPASVTQVPTAPGPLSAAASDAVGACYL
                     DLWICDRLLRHDGGNRSAAARCLVPVLLLEGVGGIAPVLGARLHRPDAVAVEYRRRRRV
                     LVRAVRERSPQTWERLGHRLARIATGEDRLARPLTPVRGRGLPQPLSELVGLLEAERRE
                     LAAAGAESVGQEPPHALLERCALLAAAAACLDGWQEAGPRREDGRERQGTAGHGIGRDG
                     AWPTPGHLSLPGRAPGGGATSASGSASGSASDSASGSASGSASGCCGGRCPVGYDPLRT
                     LGGGAALGVSARRARLCGALYRLAVRLDLRVSDVAGTAWRADVLRCAVA"
     gene            2648..3391
                     /gene="ifnC"
     CDS             2648..3391
                     /NRPS_PKS="Domain: ACPS (135-183). E-value: 3e-13. Score:
                     41.6. Matches aSDomain: nrpspksdomains_ifnC_ACPS.1"
                     /codon_start=1
                     /gene="ifnC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 141.4;
                     E-value: 4.4e-43)"
                     /gene_kind="biosynthetic-additional"
                     /product="phosphopantetheinyl transferase"
                     /protein_id="BAU98030.1"
                     /transl_table=11
                     /translation="MVPGQTLDVARQVLGRYGSVGVHADVADWAVRDEAEAVRWLGRER
                     GRLDAALPAATRQRLVASRRLVKSMAGAVLGVDPGELELTRDPAGRPRLRGCGDLELSL
                     SHTGTRLVLALAVTGGQVGADVERATRPVRVEPLARRICTPYERAVLNATSPAERPRTL
                     LRLWTLKEAYTKALGVGTRLPFRTFGFRLHGRGAVLTDDRGHLVRPSEWQFTTHHTDTG
                     HLVSLAVAGPPDGLRFPSPGLLGNL"
     aSDomain        3053..3196
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnC_ACPS.1"
                     /evalue="3.00E-13"
                     /label="ifnC_ACPS.1"
                     /locus_tag="ifnC"
                     /protein_end="183"
                     /protein_start="135"
                     /score="41.6"
                     /tool="antismash"
                     /translation="EPLARRICTPYERAVLNATSPAERPRTLLRLWTLKEAYTKALGVG
                     TRL"
     gene            3726..4478
                     /gene="ifnD"
     CDS             3726..4478
                     /codon_start=1
                     /gene="ifnD"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     284.8; E-value: 2.8e-86)"
                     /gene_kind="regulatory"
                     /product="transcriptional regulator"
                     /protein_id="BAU98031.1"
                     /transl_table=11
                     /translation="MLGQFEVVLNNGRSTTLTRSKVSQLLGLLVVQYGESIGAHTLIEE
                     LWGESVPRSALTTLQTYIYHARKLCGVGPGGHSVLVTRPAGYSIEVPGDSIDVVVFEGL
                     VGRSRTALDQGDAEKAAVLLDEAFALWRGPVLAGMITGPVLDAHLTYVNELRLSAHELH
                     IAACTRLGRHQEIIPRLRLLVAENPLNESFHAQLIKALYKSGRRAEAIQAYRNLWRILD
                     MELGIEPAPELQTLQHDLMARNSVCSVH"
     gene            4643..5227
                     /gene="ifnE"
     CDS             4643..5227
                     /codon_start=1
                     /gene="ifnE"
                     /product="FMN reductase"
                     /protein_id="BAU98032.1"
                     /transl_table=11
                     /translation="MSESPVSVVIAYHSGYGHTTKMAEGVQEGVRSVAGAVVEVITVDT
                     VTEDDWARLDAADAIIFGSPTYMGSASPDFHKFAAATSERWYGQAWKDKVAAGFTTSGA
                     MSGDKLNTLQYFTVLAAQHGMHWVNLDLLPGDTENDLNRLGGWLGAMGQCPGDQGPESM
                     RKGDVLTAAHLGRRVAEHALLLRTARARVAA"
     gene            complement(5369..6328)
                     /gene="ifnF"
     CDS             complement(5369..6328)
                     /codon_start=1
                     /gene="ifnF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 272.6; E-value: 6.4e-83)"
                     /gene_kind="biosynthetic-additional"
                     /product="esterase"
                     /protein_id="BAU98033.1"
                     /transl_table=11
                     /translation="MPSSYDIDPELAPFAERMRPLDYADPEGARSVMRQVMAAQPHYEH
                     LDRVRVEDRTLPVPGGPELTVRVYAPARPADGARPALLFPHWGGFVTGDLDTPRAFAAR
                     IADQVGAVVVSPDYRLAPEHPFPAGLDDCWAALEWTVAHAAELGVDPDRIGVGGFSAGG
                     ALATACALRARDLGGPRVRFQYLLFPQLDDRLETVSAREFTDTPVLDRASLVLCWKHYA
                     GSVSGPTPVLAAPARAQDLTGLPPAFVGVCAYDPLRDEGIQFAHRLIQAGVPTELVHYP
                     GTFHASVGIGHAAVSRRMVRDQIDALRRGLGVDGEPAA"
     gene            complement(6424..7509)
                     /gene="ifnG"
     CDS             complement(6424..7509)
                     /codon_start=1
                     /gene="ifnG"
                     /product="hypothetical protein"
                     /protein_id="BAU98034.1"
                     /transl_table=11
                     /translation="MSISRRTALTATAALAATALSAQTARAGSDDASTARRVLFEDDFS
                     GGFATSGPGARWTHIPFGGGVGQNAVATTSRRGLRLAATGSNPRTGDPAFTLTLGQHET
                     SGLPGTLDHIKWLSYPDQRTSEGTLGFAAEPGRLLIGESWMTSTTYGTAAHPFGTAVTD
                     ALDDPRLAMAGLPVEDPETGIAVDFFFTNKTVYAFYERLPHHRDTLGNYAAFTYAVPVA
                     RRSSPTAEHHIRIEYDRSRGVIRWCLDGREVFKVDRIGQLLPSRRYLVLDHGGTPTSVT
                     PRQLTFGLGMFVALDFARPGVAGSGLVRLTDEAGHYFDPVHGEPTPQSFLDADSRPENR
                     LWGQGAALGVRRFLVSSRNAG"
     gene            complement(7745..8878)
                     /gene="ifnH"
     CDS             complement(7745..8878)
                     /codon_start=1
                     /gene="ifnH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 332.7;
                     E-value: 4e-101)"
                     /gene_kind="biosynthetic-additional"
                     /product="monooxygenase"
                     /protein_id="BAU98035.1"
                     /transl_table=11
                     /translation="MSEAARDVAVEAARGAGAAEAERRLSADVVKAAVAAGFARHLVPA
                     AYGGDEGSFLELGRAVSAVGEGCTATAWCVSLAAHVGRMAAHLPEEGRREVWADGPDAF
                     FVASLTPLGTAHPEPGGYRLTGTWPFVSAIDHADWALLAAQVPNPAGGPPEPRVLAVPR
                     DAWRTEDTWHNVGMAATGSHTVTVEDLFVPAGRTVSREDLFTGRGAADVAPRLAVPMQA
                     TTMMFAVPALGAAKGALAAWRRHAERKIRAAADHPAPVLPGMPTFNRVTWDVTLTRSAT
                     EIDAAELLLERAARTLDEHGPDLTALQTMRGWRDCAMATDALVGVANRLFRGVGTTGQS
                     STNPVQRFWRDINSIAGHQALQVESAATAYAYRALDL"
     gene            8939..9424
                     /gene="ifnI"
     CDS             8939..9424
                     /codon_start=1
                     /gene="ifnI"
                     /product="hypothetical protein"
                     /protein_id="BAU98036.1"
                     /transl_table=11
                     /translation="MLCGCGPGGEGLSGGRGLGGGAPCGLSVPCGCGVLCGPGVPPGLG
                     TVPGLGILSGSGALPVPGTRPGLGIPHGPGTLPVPGSPPVPGRRPVPPGGSPPHGVPRR
                     RTVRRCGSRRTWWILTRRRGHPGCSSARIVAMGRQGGSLAVVARGSLVRRLEVSGVG"
     gene            9515..10378
                     /gene="ifnJ"
     CDS             9515..10378
                     /NRPS_PKS="Domain: Polyketide_cyc2 (125-278). E-value:
                     6.4e-16. Score: 50.9. Matches aSDomain:
                     nrpspksdomains_ifnJ_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene="ifnJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 171.8; E-value:
                     3.6e-52)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 117.4; E-value: 1.3e-36)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BAU98037.1"
                     /transl_table=11
                     /translation="MIIHTLVYRFADSVDEHQRQQFFTELEKLALGSGLVTHFGYGPHH
                     RLPVDDHARGMTANAVAQFACRDLDALRAFSELPPVHEHINAWRDRIEYDAAYANHDEL
                     LGLAAPGTTKESPMSPMSTLHHTEHTVTVDAPVATVWDVLVDVEGYARIFPPTQDVTIL
                     EESPKHQIARLVVDVNGEVQSWISRRDIDADRHVIAYRQLENAPMMGYMGGEWRALSID
                     EHTTQLVLTHDFKPRDPDADGLVAGKFTYDKADEMIKAAVERNSVADLGAVKEEAEKLV
                     GEGSAA"
     aSDomain        9890..10348
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnJ_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="6.40E-16"
                     /label="ifnJ_Polyketide_cyc2.1"
                     /locus_tag="ifnJ"
                     /protein_end="278"
                     /protein_start="125"
                     /score="50.9"
                     /tool="antismash"
                     /translation="HTEHTVTVDAPVATVWDVLVDVEGYARIFPPTQDVTILEESPKHQ
                     IARLVVDVNGEVQSWISRRDIDADRHVIAYRQLENAPMMGYMGGEWRALSIDEHTTQLV
                     LTHDFKPRDPDADGLVAGKFTYDKADEMIKAAVERNSVADLGAVKEEAE"
     gene            10375..11172
                     /gene="ifnK"
     CDS             10375..11172
                     /codon_start=1
                     /gene="ifnK"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C5-C14/C3-C16 (Score: 333.5; E-value: 2e-102)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BAU98038.1"
                     /transl_table=11
                     /translation="MTRIVDLSVVTRHTPSEATPVTVELLDHRTGATVLGLTPEDFPDG
                     MAISNETVTLTTHTGTHMDAPLHYGPLSGGKPAKSIDQVPLEWCLGPGVRLDVRHVPPG
                     EGITVEHLRGALREAGHQLRAGDIVMLWTGADELWGSAEYLTKYPGLTGEGTAFLVEAG
                     VRVIGIDAWGLDRPMRSMIEDYRRTGDQGTLWPAHVYGRTREYLQLEKLAGLATLPAAT
                     GFTVVCFPVAVEGAGAGWTRVVALLEEPEEPTEPAEAGRGAGR"
     gene            11159..11557
                     /gene="ifnL"
     CDS             11159..11557
                     /codon_start=1
                     /gene="ifnL"
                     /product="Lipocalin-like domain"
                     /protein_id="BAU98039.1"
                     /transl_table=11
                     /translation="MRADDLIGVWRLVSFEELDDTGATSRGPLGAEPSGRLIYTRDGHV
                     SVNMMRGADPGPVPYMGYAGTWWLDGSQVVHRIEVTPRSDWVDTEQTREATLENDHLTL
                     HARTRIGGAERRRVLVWRRDRRDRGDRG"
     gene            complement(11680..12984)
                     /gene="ifnM"
     CDS             complement(11680..12984)
                     /codon_start=1
                     /gene="ifnM"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 62.1; E-value:
                     7e-19)"
                     /gene_kind="regulatory"
                     /product="transcriptional regulator"
                     /protein_id="BAU98040.1"
                     /transl_table=11
                     /translation="MAFRDWGDPQRALSVAAALMQAPLKQVLSTLSDALTDLVPHHAVV
                     MLTGDCPKSATWSHGDAELTEAVTTAEMAQLATHVDIGRPRFDQASLAGAPRPVLAVAS
                     APPGSAGALLALLPTAETAPEPHVQSLVQQLWDLATLRIIALWPSAVPVNQAAPWMASS
                     ERARITADLTDSHAATLTTLLGLLRNRSLDDGTARRTAVDLAVSSLIELRSLGEGERLP
                     GEETAEEAFGRLTDMLGLLSRYGNVELEFCGPTGEAAQRVIPPVIAQTARTTARGTALT
                     MLEQGGVSRIRVSWHVEDGELRTIVRDDGPGSLAGDALAVHRLADRAAAVSGAVHVDAV
                     AGWGTIVTIRLPLSAPERRRNDPLGELNPRELDVLEQLVQGHRNRAIAERLRISEHTVK
                     FHVAKILKKLGVNSRGEAAALALAAGFPASLALTS"
     gene            13270..14538
                     /gene="ifnN"
     CDS             13270..14538
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-392). E-value:
                     6.2e-55. Score: 178.6. Matches aSDomain:
                     nrpspksdomains_ifnN_PKS_KS.1"
                     /codon_start=1
                     /gene="ifnN"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 479.9; E-value:
                     1.1e-145)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     760.8; E-value: 7.6e-232)"
                     /gene_kind="biosynthetic"
                     /product="ketosynthase alpha subunit"
                     /protein_id="BAU98041.1"
                     /sec_met_domain="t2ks (E-value: 6e-240, bitscore: 787.0,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVITGMGVRTPGANGVKAFWELLTSGRSAIRRISFFDPSPY
                     RSQIAGEADFDPVLEGLTPLEIRRMDRASQFAVVCARDAVADSGLGFEQLDPGRIGVSL
                     GSAVAAATSLEQEYLVLSDSGRDWLMDPANLSPHMFDYLVPSVMPAEVAWTVGAEGPVA
                     MVSNGCTSGIDSVGHACRLIQEGSADVMLAGACDTPITPIVVACFDAIKATTPRNGEPE
                     RASRPFDRSRNGFVLAEGAAMFVVEEYEHAVRRDAHIYAEITGYATRCNAYHMTGLKTD
                     GREMAEAIRSALDEARTDATDIDYINAHGSGTKQNDRHETAAYKRSLGEHARRTPVSSI
                     KSMVGHSLGAIGSIEIAASALAIGNGVVPPTANLHEPDPECDLDYVPLDARERRLRNVL
                     TVGSGFGGFQSAMVLRHIPGGAA"
     aSDomain        13285..14445
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnN_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.20E-55"
                     /label="ifnN_PKS_KS.1"
                     /locus_tag="ifnN"
                     /protein_end="392"
                     /protein_start="5"
                     /score="178.6"
                     /tool="antismash"
                     /translation="VITGMGVRTPGANGVKAFWELLTSGRSAIRRISFFDPSPYRSQIA
                     GEADFDPVLEGLTPLEIRRMDRASQFAVVCARDAVADSGLGFEQLDPGRIGVSLGSAVA
                     AATSLEQEYLVLSDSGRDWLMDPANLSPHMFDYLVPSVMPAEVAWTVGAEGPVAMVSNG
                     CTSGIDSVGHACRLIQEGSADVMLAGACDTPITPIVVACFDAIKATTPRNGEPERASRP
                     FDRSRNGFVLAEGAAMFVVEEYEHAVRRDAHIYAEITGYATRCNAYHMTGLKTDGREMA
                     EAIRSALDEARTDATDIDYINAHGSGTKQNDRHETAAYKRSLGEHARRTPVSSIKSMVG
                     HSLGAIGSIEIAASALAIGNGVVPPTANLHEPDPECDLDYVPLDARE"
     gene            14535..15782
                     /gene="ifnO"
     CDS             14535..15782
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (47-366). E-value:
                     3.3e-28. Score: 90.6. Matches aSDomain:
                     nrpspksdomains_ifnO_PKS_KS.1"
                     /codon_start=1
                     /gene="ifnO"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 643.5; E-value:
                     1.8e-195)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 7
                     (Score: 724.9; E-value: 5.1e-221)"
                     /gene_kind="biosynthetic"
                     /product="chain length factor"
                     /protein_id="BAU98042.1"
                     /sec_met_domain="t2clf (E-value: 1.9e-206, bitscore: 676.1,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLVTGVGLIAPNGTGPQPYWTATLAGHSGIGVLSRFDVSRYPV
                     RLAGEIRDFDAAAHLPGRLLPQTDVSTRYALVAADRALADAAIEPGAYADYDMGVVTGN
                     GQGGFEFTHREFHKLWSRGPEKVSVYESFAWFYAVNTGQISIRNQLRGPSSALVTEQAG
                     GLDAIGHARRTIRRGTPMVVTGGVDSAFDPWGWVSQMAGGRLTTSDDPARAYLPFGSDA
                     SGHVPGEGGAILILEDAATAAERGAPRVYGEIAGYASTFDPAPGTGRPPGLRRAAELAI
                     DDAGLTPADIDVVFADAAGTPDLDRAEAEAISGLFGPHGVPVTAPKALTGRLCSGGGPL
                     DVVAALLAVREGVIPPTYGTDEVPEEYGIDLVRGAPRETPVRAALVLARGRWGFNSAIV
                     VRGARGARGAGGGRDD"
     aSDomain        14676..15632
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnO_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="3.30E-28"
                     /label="ifnO_PKS_KS.1"
                     /locus_tag="ifnO"
                     /protein_end="366"
                     /protein_start="47"
                     /score="90.6"
                     /tool="antismash"
                     /translation="AGEIRDFDAAAHLPGRLLPQTDVSTRYALVAADRALADAAIEPGA
                     YADYDMGVVTGNGQGGFEFTHREFHKLWSRGPEKVSVYESFAWFYAVNTGQISIRNQLR
                     GPSSALVTEQAGGLDAIGHARRTIRRGTPMVVTGGVDSAFDPWGWVSQMAGGRLTTSDD
                     PARAYLPFGSDASGHVPGEGGAILILEDAATAAERGAPRVYGEIAGYASTFDPAPGTGR
                     PPGLRRAAELAIDDAGLTPADIDVVFADAAGTPDLDRAEAEAISGLFGPHGVPVTAPKA
                     LTGRLCSGGGPLDVVAALLAVREGVIPPTYGTDEVPEE"
     gene            15775..16305
                     /gene="ifnP"
     CDS             15775..16305
                     /codon_start=1
                     /gene="ifnP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160:flavin reductase domain protein FMN-binding
                     (Score: 143.3; E-value: 8.9e-44)"
                     /gene_kind="biosynthetic-additional"
                     /product="two component oxidase"
                     /protein_id="BAU98043.1"
                     /transl_table=11
                     /translation="MTDGFGRVSTGADRFGEVVAITDGFKEVMARFPTGVAIATVCDER
                     GLPHGLTVSSFCSVSLDPPLVLLCVAKSARSFPAFARAGEFAVSVLREHHTDLAKRFAT
                     SDEEKFRRGGLVRTPRGGLVVDDALAVVECLVDQQHDAGDHVIVVGKVVDTRTTEPGAP
                     AVYFNRRFAALSS"
     gene            16340..18256
                     /gene="ifnQ"
     CDS             16340..18256
                     /codon_start=1
                     /gene="ifnQ"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 419.4; E-value: 3.7e-127)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 23.6; E-value: 5.7e-08)"
                     /gene_kind="biosynthetic-additional"
                     /product="Bayer Billiger monooxygenase"
                     /protein_id="BAU98044.1"
                     /transl_table=11
                     /translation="MAFSRPLRPIPDDETLRRHLVAGAELPALLMTVAHLTGDASVLRD
                     DLRAPGWLFQPQGGLTAVQQEEARRVALAALARWRAEGRAPGRPDPELLRAITTWAMGS
                     DTGDLLDLLAEEIALPEDDPKAPDWTLDELSPGADFDVAVIGAGFSGLLAAHRLAQAGV
                     PVVLYEKNADVGGTWFENTYPGCRTDVASHLYNYSFAPSTDWPDHFCRSESVLEYLREF
                     AKESGVAERVRFGTEVRELRWDDTERRWHLTLRGPDGATRTVTHRAVITAVGQLNRPAL
                     PAVEGLGSFTGPAFHSAAWDHSVDLAGKRVAVVGTGASAYQLVPELAGVASEVVLFQRN
                     PPWLRPTPHYHEPVSDSAAWLFEHVPYYTQWYRFWLFAPGLRGILDGWIVDHDHPPTER
                     AISALNEQLRASLLQSMEAQLTDAPELRDKVIPNYPVGAKRVLRDNGTWLATLKRDDVT
                     LVTAPVARETPHGLVADGEEFAVDVIVYATGFEASRFLTPMKVTGENGLDLHTHWAGAP
                     RAHLGVSVPHFPNLFCLYGPNTNLVGQGGSIVYFSECATRYVVDVIRLLLARGADAAQV
                     REDIHDDYNAWVDAASADRAWVWSKVSGWYKDGGRSSTNWPFSAVEYWTRTRRADPDDL
                     HVS"
     gene            18342..19493
                     /gene="ifnR"
     CDS             18342..19493
                     /codon_start=1
                     /gene="ifnR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191:acyl-CoA dehydrogenase type 2 (Score: 330.4;
                     E-value: 1.9e-100)"
                     /gene_kind="biosynthetic-additional"
                     /product="FMNH2 dependent monooxygenase"
                     /protein_id="BAU98045.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.7e-10, bitscore:
                     31.2, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDTTPGRLTEAARQLADTAVGLAPAMTERRRIDADLVKAMREAG
                     FMRHFVPARYGGAAGTFTDLLAAVATLGEACPATAWCASLFASTPRFVPCFPEAGQREF
                     WAEGPDTAFVCSVLPFGEATPASGDSGLRVSGRWPYMSAVEYADWVIVCARLPGADGPR
                     LKLVAVPVSAVSVEDTWDTVGMRATGSNTVVLDDVLVPAARVVDRDAVFGGRPVDAPET
                     PIAPLAAVNGLTFVVPALGAAQGALAELARYLGGKLRNVSPTPGVPGPGGTLASQEMTL
                     ARSAAEIDSARLLLTRIAELGDAQGPFTPPVVARNVRDSAFAVELLVTAVNRIFRGAGT
                     GGQVAHGPLERFWHDVNAVATHQALQFEPAAHHYARALLTTDA"
     gene            19514..20590
                     /gene="ifnS"
     CDS             19514..20590
                     /codon_start=1
                     /gene="ifnS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 252; E-value:
                     1.5e-76)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 270.8; E-value: 3.7e-83)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BAU98046.1"
                     /transl_table=11
                     /translation="MTSPPLDTATPLDTATAQAPTTPSADRIMETALAFEASKTLLSAV
                     EIGVFTELARRPADAAELRDRLGLHPRGARDFFDALVALGFLRRVDGVYHNTPETDAHL
                     DRAKPGYGTVAPLLEMANSRLFGIWNHLTDVLRTGLSHDESKDSGQDTYDALYADPARL
                     KQFLASMTGISHRANLRIARQVPWEDYSTVADMGTAQGDLVTQVLLANPHLTGTGFDLP
                     EAEPVFTEYAERHGLGERLRFTGGDFFTDPFPKADVLTFGHILHNWDLDRKKLLLRRAW
                     EALPAGGAVVVYDTLIDDERSENAFALLMSLNMLAVTDGGFGYTGAECQEWMREAGFAR
                     AWTEHLVGPDSIVVGVKE"
     gene            20587..21012
                     /gene="ifnT"
     CDS             20587..21012
                     /codon_start=1
                     /gene="ifnT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BAU98047.1"
                     /sec_met_domain="PF07366 (E-value: 1.7e-13, bitscore: 41.3,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAQEQQAQLKANKELVAEYIRLFYNEKDFDRARELLTEGFVNH
                     HHGVGAGRDRTVETFSAAASAMPEFSLTVRRVVAEDDQVWTQSVARAAPGARPSVVVDI
                     WRIEDGRLAEHWDVGQAVPDGSTLDEMIEDAVAGDAG"
     gene            21009..21956
                     /gene="ifnU"
     CDS             21009..21956
                     /NRPS_PKS="Domain: PKS_ER (21-312). E-value: 6.8e-60.
                     Score: 194.6. Matches aSDomain:
                     nrpspksdomains_ifnU_PKS_ER.1"
                     /codon_start=1
                     /gene="ifnU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 302.7; E-value: 5.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /product="enoyl reductase"
                     /protein_id="BAU98048.1"
                     /sec_met_domain="ADH_N (E-value: 2.6e-13, bitscore: 40.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5e-23, bitscore:
                     72.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELMQAVTQRAFGGPDVLEAAEVLRPGPGLNEVLVRVHAAGVNP
                     IDALVRSGTLPLLGAPPFTVGWDISGVVVEVSPGVTRFAVGDEVYGMPYIPRAAAAYAE
                     YAVAPSRQLARKPATVDHRTAAALPLAGLTAWQALADTGLVGTGTRVLVHGGAGGVGHL
                     AVQIAKARGAEVIATASTAKTDFVRELGVDQVIDYRTRDFTEEVKDVDVVLDGVGGETA
                     ERSLDVLRPGGALVTIVEMRNTDLAARAETRGLSFHGVTAEPDHVGLTALADLVDSGRL
                     RPHIAQALPLSRAAEAHRLLEAGTLPGKVVLQAA"
     aSDomain        21072..21944
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ifnU_PKS_ER.1"
                     /evalue="6.80E-60"
                     /label="ifnU_PKS_ER.1"
                     /locus_tag="ifnU"
                     /protein_end="312"
                     /protein_start="21"
                     /score="194.6"
                     /tool="antismash"
                     /translation="AEVLRPGPGLNEVLVRVHAAGVNPIDALVRSGTLPLLGAPPFTVG
                     WDISGVVVEVSPGVTRFAVGDEVYGMPYIPRAAAAYAEYAVAPSRQLARKPATVDHRTA
                     AALPLAGLTAWQALADTGLVGTGTRVLVHGGAGGVGHLAVQIAKARGAEVIATASTAKT
                     DFVRELGVDQVIDYRTRDFTEEVKDVDVVLDGVGGETAERSLDVLRPGGALVTIVEMRN
                     TDLAARAETRGLSFHGVTAEPDHVGLTALADLVDSGRLRPHIAQALPLSRAAEAHRLLE
                     AGTLPGKVVL"
     CDS_motif       21381..21425
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ifnU_0001"
                     /evalue="3.70E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="ifnU"
                     /protein_end="139"
                     /protein_start="124"
                     /score="10.9"
                     /tool="antismash"
                     /translation="AAALPLAGLTAWQAL"
     CDS_motif       21450..21512
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ifnU_0002"
                     /evalue="4.50E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="ifnU"
                     /protein_end="168"
                     /protein_start="147"
                     /score="22.3"
                     /tool="antismash"
                     /translation="GTRVLVHGGAGGVGHLAVQIA"
     CDS_motif       21522..21563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ifnU_0003"
                     /evalue="3.40E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="ifnU"
                     /protein_end="185"
                     /protein_start="171"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GAEVIATASTAKTD"
     CDS             22336..23715
                     /codon_start=1
                     /note="orf2"
                     /product="hypothetical protein"
                     /protein_id="BAU98049.1"
                     /transl_table=11
                     /translation="MTGMTDDRQGPAFSRRGLIGAGVGAAVLAVAGAGAAHAGVGSARR
                     RGHDFLAAAMDAYPDHGAVRLAQSYTDQAGLFSTAFTYDNALAILAHLAVGNADGRARA
                     VVLGDALLYAQGHDPVHDDGRLRQAYNVGPYTFYDGSVQPDGFVRADGSANVGTQFGFT
                     GTAVGDMAWAGIALGALARRTGGRRFLDGAVRVGEWIERNGRTDEPLGGYKFGVNGANE
                     KLPFTSTEHNTDLVCLFGRLARLTGDRVWLERRARAREFVGRMWEADGGFFYTGTNDGI
                     SINTSPVPEDTQTWTHLALDSRAHASSLDWAARELAVLDHAGRRNSTVPAGQSYEGVTF
                     SSASLLANEDAPIADSQPRPDRNGVWFEGTAHLALALRERQGRGDEARARRLVESIERA
                     QDLLGAGQSVGGRALPGRSGVVAASSPLDTGFGFGYYPYRHTGATAWYLMAATRFNPLR
                     V"
     CDS             23802..24392
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 100.5; E-value: 2.1e-30)"
                     /gene_kind="other"
                     /note="orf3"
                     /product="transcriptional regulator"
                     /protein_id="BAU98050.1"
                     /transl_table=11
                     /translation="MARNVRLLREQRGLSLAELARQAGLAKQTLSKLEQGTGNPTVDTL
                     FSIAQALGVPVTRLVAEREQVMTVQRADEVVWQQHGGYESRSLDHVYGSGVIENYLVRI
                     APDADGAGTVSEPHPVGTLEHLYVISGRVRVGPSDSPVELSSGDFVRYPGDRPHVYESL
                     DGESLVHIVVSVPRVQPGTGGTTVARTHGNGLR"
     CDS             complement(24409..25212)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195:IclR family
                     transcriptional regulator (Score: 236.5; E-value: 4.2e-72)"
                     /gene_kind="regulatory"
                     /note="orf4"
                     /product="transcriptional regulator"
                     /protein_id="BAU98051.1"
                     /transl_table=11
                     /translation="MPMPSPTAPSTSEQQTAVDKALILLKQLAEHDHELGVSELARRTG
                     LTKSTAFRLLAILQRNDLVERVGSDYRLGAQLFDIGTRVYGPTTVLLRERLLPHLADLY
                     VLTHETVHLAVLHDTEIVYVNKIHGHRPTRSPSRIGARMPAYCTGVGKALLAFDHDAAE
                     AAVEAGLHGRTEYTLTDPTAFRSELRRIRQEGIAYDRQEATLGLTCVAVPVMGPGGRPV
                     AALSVAGAGHRFDPARYAPALRRVAYEAARAVTTARAGLGSPPAA"
ORIGIN
        1 gcgtcggcca ggggtgggac gtggtggacc gggcccggct gggctgtgcg atggcctcgc
       61 tcgtccttgt caccgtgggc acccagacct atacggtcga accggcccgg ctcggctcgg
      121 cgctcacccg cgcctacgga gaccgtgccg cggcactcgc ggatctggaa cgggtggtgg
      181 gggtgacggt ggcatgacgg acatcgcgct ggtgaccggg gccaacaagg gcctcggcaa
      241 ggagatcgcg cggcggctcg cggccgaggg gctgaccgtg tacctggggg cgcgggacga
      301 gacacggggg cgtgtggccg cgggcgaact gagggcggcc ggcctcgacg tgcggttcgt
      361 gcggctcgac gtcaccgtgc gggagcaggt cgacgcggcg gtccggacgg tcgacgagga
      421 gtgcggcagg ctcgacgtcc tcgtcaacaa cgccgggatc gtcaccgagt ggggcctgcc
      481 cgtcgaggac atcaccgagg accatctgcg ccgggcgttc gaggtcaacg tcctcggcac
      541 ggtcgccgtg acgcgcgcgt gcctgccgct gctgcggcgc tcgaaggacg ccagagtggt
      601 caacctgtcc agtccgctcg ggtcgttgac cctcctcgac gaccccgagc acccggcggc
      661 ctcgcgggga ctgctcgcct acagctcctc caaggccgcc ctcaacgcgg tgaccctggt
      721 gtacgccgag gcgctgcgcg acgccgggat ccgcgtcaac gcggccaacc ccgggctcgt
      781 ggccaccgac ctgaacgccg actcgccgtt cagccggggt acccgcacgg tcgaggaggg
      841 cgccgaggtc cccgtacggc tggcgttggg tgccgggggg acgggcggct tccacgggag
      901 catggaggga gacgtggccg aacgcgtgcc gtggtgacgg gcacgtggtc atggggcggc
      961 ccccggcagc ggtgatgctg tcgggggccg aggtcgtggt cgtggccgta gctgtggctt
     1021 ttgccgtggc tgtggtcgtg gatacggcgg gcaggtcacc cgccggtgcg gaccgctccg
     1081 ttggccaggt cgagcagggt gcgcggggta cgggcctcgc tcacctcctc gtcgggcagc
     1141 acgatcccgt actcctcctg gatggccgcg gccgtctcca tgagggcgag cgagtcgtaa
     1201 cccagctcct cgaaaggggt gtcgagggtg tcgccgccca gccgggagcc ctcctcttcg
     1261 ccggcgcagg ccaccaggat gcggcgcagg tcctcgatgc caacagtcgc catcgcagtc
     1321 gtctcctcgg gctcggtggg tgtcacatga cgtggacggt ccccgtcacg cgcatcgtgc
     1381 ggccaccccc ttggagcccg ctggaaccgg cccagcaccc ctccgccgca ctcccatccg
     1441 cctccgatgc cgagcgccga tggtgaggcc tcgccgaacg gggccttcgt aaaggagcgc
     1501 ggtgagccat gcggacacag gaccgacgag gaccgtggga cggccggagc gacagcggtg
     1561 gcggcgtggc gacggccccg cgggcggggc tgcgggtcgt cggacccggg gcggcacggg
     1621 ggcccttgga acccgggcgc ctgctcagtc atgcgacggc cgcgctgcac gtggtcgtcg
     1681 atgccgtggg tgccccggca tccgtcacgc aagtccccac ggcaccgggc cccttgagcg
     1741 ccgccgcctc cgatgccgtg ggcgcctgct acctcgacct gtggatctgc gaccggctcc
     1801 tccggcatga cggagggaac cggtccgccg ccgcgcggtg cctggtcccc gtgctgctgc
     1861 tggagggggt cggcgggatc gcgcccgttc tgggggcgcg gctgcaccgg cccgacgccg
     1921 tggccgtgga gtaccggcgt cggcggcgcg tgctggtgcg cgcggtgcgg gagcggtccc
     1981 cgcagacgtg ggagcggctc ggtcaccggc tcgcccgcat cgccaccggg gaggacaggc
     2041 tggcccggcc cctcaccccg gtacgcggcc gtgggctgcc gcagccgttg tcggagctgg
     2101 tcggcctgct ggaggcggaa cggcgtgaac tggccgcggc cggcgccgag tcggtcggcc
     2161 aggaaccacc gcacgccctc ctggagcgct gcgccctgct cgccgcggcc gccgcctgcc
     2221 tcgacggctg gcaggaggcg gggccgcgtc gggaggacgg acgcgaacgg cagggcacgg
     2281 ctggccacgg catcggccgc gacggtgcct ggccgacgcc cgggcacctt tccctgcccg
     2341 ggcgtgctcc cggcggggga gcgacttcag cgtcgggctc ggcctcgggt tcggcgtctg
     2401 actcggcctc gggttcagcg tctggctcgg cctcgggttg ctgcggtggt cgttgccccg
     2461 tcggctacga ccctctgcgc acgctcggcg gaggcgccgc cctcggcgtc tccgcgcggc
     2521 gggccaggct gtgcggggcg ttgtatcggc ttgccgtgcg gcttgatctg cgggtctccg
     2581 atgtggcggg caccgcgtgg cgggcggatg tgctgcggtg cgcggtggcg tgacgccgct
     2641 gttggccgtg gtgccgggcc agaccctcga cgtggcgcgg caggtgctcg ggcggtacgg
     2701 cagtgtgggc gtccacgcgg atgtcgcgga ctgggccgtg cgcgacgagg cggaggccgt
     2761 acggtggctc ggccgtgagc gggggcggct ggacgcggcg ctcccggcgg ccacacggca
     2821 gcggctcgtg gcgtcccggc ggctggtcaa gagcatggcg ggcgcggtcc tcggcgtcga
     2881 tccgggggag ctggagctga cccgcgatcc cgccggccgc cctcggctgc ggggctgcgg
     2941 cgacctggag ctgagcctga gtcacaccgg cacccggctg gtgctcgcac tcgctgtgac
     3001 cggagggcag gtcggggcgg acgtggagcg ggccacccgc ccggtgcggg tggaaccgct
     3061 cgcccggcgg atctgcaccc cctacgaacg ggcagtgctc aacgccactt caccggccga
     3121 acgcccccgc acactgctga ggttgtggac cttgaaggag gcctacacca aggcactcgg
     3181 cgtgggcacg cggctgccct tccgcacctt cggattccgg ttgcacggtc gcggcgcggt
     3241 tctgaccgac gaccgggggc acctcgtccg gccctcggag tggcagttca cgacgcatca
     3301 caccgacacc ggacatctgg tcagcctggc cgtcgccggc ccgccggacg gcctccgctt
     3361 tccgtccccg ggactcctcg ggaatctctg attatgaatt ctcaggtttt gccgaatatt
     3421 gagaaatcgc tttcggctga tcaattccca gcctaaagcg cagccactat tttgggcagt
     3481 tcatggctag tgtgacgccg atcactgcgg agtctgtggc acgaatgcgc ctgttcttat
     3541 accgtccaat atgttcctgg actggaccgc caggtgagcg cgggcaggcg tactggggag
     3601 cagcggcgaa gtctcgatca ctccgtattc tgcgatgcat cggtttcgga cggagatcgc
     3661 cgcgcgattc gaccagccct tgttgcgtgc ccgcaaaaaa tgggggaaag aaattgaagt
     3721 tcaaactgct cggacagttc gaggtagtcc tgaacaacgg gcgctcgacc acgttgacca
     3781 ggtcgaaagt cagccaactc ctcgggctgc tcgtcgtgca gtacggcgag tcgatcggcg
     3841 cccacaccct gatcgaggag ctgtgggggg agagcgtgcc gcgcagcgcg ctcaccacgc
     3901 tgcagacgta catctaccac gcgcgcaagc tctgcggggt cgggcccggc ggccactccg
     3961 tcctggtgac ccggcccgcc ggctacagca tcgaggtacc cggcgacagc atcgacgtcg
     4021 tcgtgttcga gggcctggtc ggccggtccc gcaccgcact ggaccagggg gacgcggaga
     4081 aggccgccgt cctgctcgac gaggcgttcg cgctctggcg cggccccgtc ctggccggca
     4141 tgatcaccgg cccggtgctc gacgcccacc tgacctacgt caacgaactg cggctgtccg
     4201 cgcacgaact gcacatcgcg gcctgcaccc ggctcggccg ccaccaggag atcatcccgc
     4261 ggctgcggct gctggtcgcg gagaatccgc tcaacgagag tttccacgcc cagctcatca
     4321 aggcgttgta caaaagcgga cgacgcgccg aggccatcca ggcctaccga aacctctggc
     4381 gcatactcga catggagctg ggtattgaac ccgctccgga actccagacg ctccagcacg
     4441 acctgatggc ccggaattcc gtttgttccg tccactgatc gtcccttcgg ctgctccttc
     4501 gggtaggtgt ttttgcccga aggagcagtg ccccggcggg tgcgctgctg acaggctgga
     4561 ggcgtaatcc gatccgcggt tcgtatgcaa tcgggtgcgc cattaatccg tagccctgca
     4621 tatgtcgtcc gaagggaaaa caatgtctga atccccggta tccgtcgtca tcgcctacca
     4681 cagcgggtac gggcacacca cgaaaatggc cgagggcgtc caggagggcg tgcgttccgt
     4741 ggcgggcgcc gtggtcgagg tgatcacggt cgacaccgtc accgaggacg actgggcccg
     4801 gctcgacgcc gccgacgcga tcatcttcgg ctcgcccacc tacatgggtt cggccagccc
     4861 ggacttccac aagttcgccg cggcgaccag cgagcgctgg tacgggcagg cctggaagga
     4921 caaggtcgcg gccggtttca ccacctccgg cgcgatgagc ggcgacaagc tgaacaccct
     4981 gcagtacttc acggtgctgg ccgcgcagca cggcatgcac tgggtcaacc tcgacctgct
     5041 gcccggcgac acggagaacg acctcaaccg gctgggcggc tggctgggtg ccatgggcca
     5101 gtgcccgggc gaccaggggc ccgagtccat gcgcaagggg gacgtgctca ccgcggccca
     5161 cctcgggcgc cgggtggccg agcacgcgct gctgctgcgc acggcccgcg cgcgcgtggc
     5221 cgcctgacgc cgccatcggc gtaccgcagg acgcacgaac gcacgaacgc atgacggagg
     5281 ggccccgggt cgtatgaccc ggggcccctc gtctcgtcgt cgtacgcgga cagggcggac
     5341 agccctgcgg ggacatggct ggacagcgct atgcggcagg ctctccgtcc acgcccagcc
     5401 cgcgccgcag cgcgtcgatc tggtcgcgca ccatgcgccg ggagacggcc gcgtggccga
     5461 tgccgacgga ggcgtggaac gttcccgggt agtggaccag ttcggtcggc acgcccgcct
     5521 ggatgagccg gtgcgcgaac tggatgccct cgtcgcgcag cgggtcgtag gcgcacaccc
     5581 cgacgaacgc cggcggcagc cccgtcagat cctgcgcgcg agccggcgcc gcgaggaccg
     5641 gggtcgggcc ggagaccgag cccgcgtagt gcttccagca gagcacgaga ctggcccggt
     5701 ccagcaccgg ggtgtccgtg aactcccgtg ccgacacggt ctccaggcgg tcgtcgagct
     5761 gcgggaacag caggtactgg aagcggacgc gaggcccgcc gaggtcacgg gcgcgcagcg
     5821 cgcaggcggt ggccagggca ccgcccgcgc tgaacccgcc cacgccgatc cggtccgggt
     5881 cgacgcccag ctcggcagcg tgcgcgacgg tccactccag ggccgcccag cagtcgtcca
     5941 ggcccgccgg gaaagggtgt tcaggggcga gccggtagtc gggcgagacc accaccgcgc
     6001 ccacctggtc ggcgatccgg gcggcgaacg cgcgtggcgt gtccagatcg ccggtgacga
     6061 acccgcccca gtgcgggaag agcagcgcgg gccgagcgcc gtcggccggc cgcgccgggg
     6121 cgtagacgcg gacggtcagc tccgggccgc ccggtaccgg cagggtgcgg tcctccaccc
     6181 gcacccggtc gaggtgctcg tagtgcggtt gcgcggccat cacctgccgc atcaccgacc
     6241 gcgcgccctc ggggtcggcg tagtccagcg gccgcatccg ctcggcgaac ggggccagtt
     6301 cgggatcgat gtcgtacgac gatggcatgg cggctcctcg aagggcgcgt agggaacacg
     6361 gccggaactc agccggaact aggccggaac tcggccggaa gtcagccgga ctcaggcgga
     6421 aactcagccg gcgttgcggc tggagaccag gaagcggcgg accccgagag cggcgccctg
     6481 gccccagagc cggttctccg ggcggctgtc ggcgtcgagg aaggactgcg gggtgggctc
     6541 gccgtgcacc gggtcgaagt agtgccccgc ctcgtcggtc agtcggacga ggccggaacc
     6601 ggcgacaccc gggcgggcga agtccagggc gacgaacatg cccaggccga aggtgagttg
     6661 acgtggggtc accgaggtcg gggtgccgcc gtggtcgagc accaggtacc ggcgggaggg
     6721 cagcagctgg ccgatgcggt cgaccttgaa cacctcgcgg ccgtccaggc accagcggat
     6781 gacgccgcgc gagcggtcgt actcgatcct gatgtggtgc tcggcggtcg gcgaggagcg
     6841 gcgggcgacc gggacggcgt aggtgaaggc ggcgtagttc ccgagcgtgt cacggtggtg
     6901 ggggaggcgc tcgtagaagg cgtacaccgt cttgttggtg aagaagaagt cgacggcgat
     6961 gccggtctcc gggtcctcga cgggcagtcc ggccatggcg agccgcgggt cgtccagggc
     7021 gtcggtgacc gcggtgccga aggggtgggc ggcggtgccg taggtggtgg acgtcatcca
     7081 ggactcgccg atcaggaggc ggcccggctc ggcggcgaag ccgagggtgc cctcgctcgt
     7141 gcgctggtcc gggtacgaca gccacttgat gtggtcgagg gtgccgggca ggccgctcgt
     7201 ctcgtgctgg cccagcgtca gggtgaacgc ggggtcgccg gtgcgggggt tgctgcccgt
     7261 cgcggcgagc cgcaggccgc gccgggaggt ggtcgccacg gcgttctggc cgacgccgcc
     7321 gccgaacggg atgtgggtcc agcgggcgcc ggggccgctg gtggcgaagc cgccggagaa
     7381 gtcgtcctcg aacaggacgc ggcgggcggt ggaggcgtcg tccgaaccgg ctctggcggt
     7441 ctgggcggac agggcggtgg cggcgagggc ggccgtggcg gtgagggcgg tgcggcggct
     7501 tatggacatg cggggtcctt tccggagtgg ggtggggcgg tgttgtcgtg cggattggtc
     7561 ggcggtggga tgtgacgacg tgagaggggg gggtgggggt gtttcgcccc cgccgcccct
     7621 acccgtcccg tccctggggg cctgcggccc ccagaccccc gcttcggccc ttaaggggcc
     7681 ttgtcctcaa gcgccggacg ggctggattg cgtgggccgg cgtcgaaagg gtggggtcct
     7741 tgggtcacag gtccagcgcc cggtaggcat acgcggtggc cgcggactcg acctggaggg
     7801 cctggtgtcc ggcgatcgag ttgatgtcgc gccagaagcg ctgcaccggg ttggtcgagg
     7861 actggcccgt ggtgccgacg ccgcggaaca gccggttggc cacgccgacc agggcgtcgg
     7921 tggccatcgc gcagtcccgc cagccgcgca tcgtctgcag ggcggtgagg tcggggccgt
     7981 gctcgtcgag cgtgcgggcg gcccgttcca ggaggagttc ggccgcgtcg atctcggtgg
     8041 cgctgcgggt cagcgtcacg tcccaggtga cgcggttgaa ggtcggcatg ccgggcagca
     8101 cgggggccgg gtggtcggcg gcggcgcgga tcttccgctc ggcgtggcgt cgccaggccg
     8161 cgagcgcccc cttggccgcg cccagtgcgg gcaccgcgaa catcatggtc gtcgcctgca
     8221 tcggcacggc gagccgaggc gcgacgtccg cggcgccgcg cccggtgaag aggtcctcac
     8281 ggctgacggt acggccggcc gggacgaaca ggtcctcgac ggtgacggtg tggctgccgg
     8341 tcgcggccat gccgacgttg tgccaggtgt cctcggtgcg ccaggcgtcc cggggcaccg
     8401 cgaggacgcg cggctcgggc gggcccccgg cggggttcgg cacctgggcc gcgagcaggg
     8461 cccagtcggc gtggtcgatc gcgctgacga agggccaggt gccggtcagg cggtagccgc
     8521 cgggctcggg gtgcgcggtg ccgagcgggg tgagggaggc gacgaagaag gcgtccgggc
     8581 cgtccgccca cacctcgcgc cggccctcct cgggcagatg ggccgccatc cggccgacgt
     8641 gcgcggccag cgacacgcac caggcggtcg cggtgcaccc ctctcctacg gcgctcacgg
     8701 cccgccccag ctccaggaaa ctcccctcgt caccgccgta cgcggccggc acgagatgcc
     8761 gtgcgaaccc ggcggcgacc gccgccttga ccacgtccgc cgacagccgc cgctcggcct
     8821 cggcggcccc ggcgccccgc gcggcctcga ccgcgacgtc ccgcgctgcc tcggacagcg
     8881 gcgcccggtt ctcccgggcg ggcgtggccg cgacggcttg cgtcgtctcg gaagtggtgt
     8941 gctgtgcggc tgtggaccgg ggggagaggg tctctccggt gggcgtggcc tcggcggcgg
     9001 ggctccgtgt ggtctcagtg tcccgtgcgg ctgcggtgtc ctgtgcggtc ccggcgtccc
     9061 gcccggcctc ggcactgtgc ctggcctcgg cattctgtcc ggctccggcg ctctgcccgt
     9121 ccccggcacc cggcctggcc tcggcattcc gcacggaccc ggcaccctgc ccgtccccgg
     9181 ctccccgccc gtccccggac gccgcccggt tccccccggc ggcagccccc cgcacggcgt
     9241 ccctcggcgc cgtaccgtcc ggcggtgcgg aagtcgtcgt acgtggtgga ttctgactcg
     9301 gcgtcggggc catcctggtt gctcctcggc tcggattgtc gcgatgggtc ggcagggcgg
     9361 gagcctcgcc gtcgtcgccc ggggatcgct tgtccggcgc ttggaggtgt ctggcgtcgg
     9421 gtgacccggc tcccagtggt ctcccagccg cccgagaggc gccgcctgga cgctgtcccc
     9481 cgttgccgct tccagtgcgc ctcggaggag acccgtgatc atccacaccc tcgtctaccg
     9541 gttcgcggac tcggtcgacg agcaccaacg tcagcagttc ttcacggagt tggagaagct
     9601 cgcgctcggc tcgggcctcg tcacgcactt cgggtacgga ccgcaccacc gcctgccggt
     9661 ggacgaccac gcgcggggga tgaccgcgaa cgccgtcgcc cagttcgcgt gccgcgacct
     9721 cgacgcgctg cgggccttct cggagctccc gcccgtgcac gagcacatca acgcctggcg
     9781 ggaccggatc gagtacgacg ccgcctacgc caaccacgac gaactgctcg gcctcgccgc
     9841 gcccggaacc acgaaggaga gccccatgag ccccatgagc accttgcacc acaccgaaca
     9901 caccgtcacc gtcgacgccc cggtcgccac cgtctgggac gtcctggtcg acgtcgaggg
     9961 gtacgcccgt atcttcccgc ccacccagga cgtcacgatc ctggaggagt cgcccaagca
    10021 ccagatcgcc cggctcgtcg tcgacgtcaa cggcgaggtg cagtcgtgga tctcgcggcg
    10081 cgacatcgac gccgaccgtc acgtcatcgc ctaccggcag ctggagaacg ccccgatgat
    10141 gggctacatg ggcggcgagt ggcgggcgct gtccatcgac gagcacacca cccagctggt
    10201 cctcacgcac gacttcaagc cgcgcgaccc ggacgcggac ggcctggtcg ccgggaagtt
    10261 cacctacgac aaggccgacg agatgatcaa ggccgccgtg gagcgcaaca gcgtggccga
    10321 cctcggcgcg gtcaaggagg aggccgagaa gctcgtcggc gagggctcgg ccgcgtgacg
    10381 cgcattgtcg acctgagcgt ggtcacccgg cacacgccga gcgaggcaac gccggtcacc
    10441 gtcgagctcc tggaccatcg caccggcgcc accgtgctcg ggctgacgcc ggaggacttc
    10501 ccggacggga tggcgatctc caacgagacg gtgaccctga ccacccacac cggcacgcac
    10561 atggacgcgc cgctgcacta cggcccgctc agcggcggca agcccgccaa gagcatcgac
    10621 caggtcccgc tggagtggtg cctggggccg ggcgtgcggc tggacgtacg gcatgtgccg
    10681 cccggtgagg gcatcaccgt cgagcatctg cgtggggcgc tgagagaggc cgggcatcag
    10741 ctgcgggccg gcgacatcgt gatgctgtgg accggagccg acgaactgtg gggctccgcc
    10801 gagtatctga cgaagtatcc ggggctcacc ggagagggca cggcgttcct ggtggaggcc
    10861 ggggtccggg tcatcggcat cgacgcctgg gggctcgacc ggcccatgcg gtcgatgatc
    10921 gaggactacc gcaggacggg cgaccagggc acgctgtggc ccgcccacgt gtacgggcgc
    10981 acccgggagt acctccagct ggagaagctc gcgggcctcg cgacgctgcc cgcggcgacg
    11041 ggcttcacgg tggtgtgctt cccggtggcc gtcgagggcg ccggcgcggg ctggacccgg
    11101 gtggtggcgc tcctggagga gccggaggaa ccgacggaac cggcggaagc gggccgcggt
    11161 gcgggccgat gacctgatcg gggtgtggcg gctggtgtcg ttcgaggaac tggacgacac
    11221 cggcgccacc tcccggggtc cactgggcgc cgagccgagc ggccggctca tctacacccg
    11281 ggacggccac gtctcggtga acatgatgcg cggcgcggat cccggccccg tcccgtacat
    11341 gggctatgcc gggacctggt ggctggacgg ctcccaggtc gtgcatcgca tcgaggtcac
    11401 tccccgctcc gactgggtcg acaccgaaca gacccgtgag gcaaccctgg agaacgacca
    11461 cctgaccctg cacgcccgca cccgtatcgg gggtgcggaa cgccgccggg tcctggtctg
    11521 gcgcagggac cgcagggacc ggggggaccg ggggtagggc gctgcccccg ggagatctgg
    11581 gtgccccatg cgtgaaggcc gcgaccccgg gacgacggtc gcggccttca cacccgctct
    11641 tgctgccaca cctcttgctg ccacaccctg ctcatgccgc tacgacgtca acgccagcga
    11701 cgccgggaac cccgccgcca gagccagtgc cgccgcctcg ccccgcgagt tgacgcccag
    11761 cttcttcagg atcttcgcca cgtggaactt caccgtgtgc tcgctgatcc gcagtcgctc
    11821 ggcgatggcc cggttgcgat ggccctggac gagctgttcc aggacgtcca gctcgcgggg
    11881 gttgagctcg cccagcgggt cgttgcgccg gcgctcgggt gcgctcaggg gcagtcgtat
    11941 ggtgacgatc gtgccccagc cggccaccgc gtcgacgtgc acggcaccgc tgacggcggc
    12001 ggcccggtcg gcgagccggt gcacggcgag cgcgtcgccg gccagggagc ccgggccgtc
    12061 gtcccggacg atcgtgcgca gctcgccgtc ctcgacgtgc cagctgaccc ggatccggct
    12121 gacaccgccc tgctccagca tggtcagcgc ggtgccccgg gccgtcgtcc gcgccgtctg
    12181 cgcgatcacc ggagggatga cccgctgcgc cgcctcgccg gtgggcccgc agaactccag
    12241 ctccacgttg ccgtagcggg acagcagtcc gagcatgtcg gtgagccggc cgaacgcctc
    12301 ctcggcggtc tcctcacccg gcagccgctc gccctcgccg agcgagcgca gctcgatcag
    12361 cgaggacacc gccaggtcga cggcggtgcg ccgcgcggtg ccgtcgtcga ggctgcggtt
    12421 gcgcagcagg ccgagcagcg tggtgagcgt cgcggcgtgg gagtccgtca gatcggctgt
    12481 gatccgggcc cgttcgctgc tcgccatcca gggtgccgcc tggttcacgg ggacggcgct
    12541 gggccacagg gcgatgatcc gcagcgtggc caggtcccac aactgctgca ccagtgactg
    12601 aacatggggc tccggtgcgg tctccgcggt cggcagcagc gccagcaggg cgcccgccga
    12661 accggggggc gcggaggcca ccgcgaggac cggacgcggc gcgcccgcca gcgaggcttg
    12721 gtcgaacctg ggccggccga tgtcgacgtg ggtggcgagc tgggccatct ccgccgtggt
    12781 gaccgcctcg gtcagttcgg cgtccccatg gctccaggtc gccgacttgg ggcagtcgcc
    12841 ggtcagcatg accacggcgt ggtgcggtac gaggtcggtg agtgcgtcgg acagggtgga
    12901 cagtacctgc ttgaggggtg cctgcatcag cgccgccgca acggacaggg cacgctgcgg
    12961 gtccccccag tcccgaaatg ccatgttctt catgctacgg gccacgggct cgccccgcac
    13021 tcgccaaccg gccggtcgcc actagccgtt cgggtagtcc gtccgcgaac ccgcgcggca
    13081 ctccgtcccg cccggccggt ccgggccgcc ctcccaccat cctcccagcg ccttcccagc
    13141 ggtccgtaga gccgcatcgg ccatcgtcgg cacggcgcac ggcacaccgc cgtacgccca
    13201 cagcttcggc gcacaagggg gccacagggt gagcgagtca gcagcagctc ggacgacggg
    13261 cgggacgcga tgacccgccg aacggtgatc accggcatgg gggtgcgtac ccccggcgcg
    13321 aacggcgtga aggccttctg ggaactgctg acctccggac gcagcgccat ccgccgcatc
    13381 tccttcttcg atccctcgcc gtaccggtcg cagatcgccg gcgaggccga cttcgacccg
    13441 gtgctggagg gcctcacccc gttggagatc cggcggatgg accgcgcctc ccagttcgcc
    13501 gtggtctgcg cgcgggacgc ggtcgcggac agcggcctcg gcttcgaaca gctggatccg
    13561 ggccggatcg gggtgagcct cggcagcgcg gtggccgcgg cgaccagcct ggagcaggag
    13621 tatctggtgc tgtcggacag cggccgtgac tggctgatgg accccgccaa cctgtcgccg
    13681 cacatgttcg actacctggt gccgagcgtg atgcccgccg aggtggcctg gacggtcggc
    13741 gcggagggcc cggtggcgat ggtctccaac ggctgcacct ccggcatcga ctccgtcggc
    13801 cacgcctgcc gcctcatcca ggagggcagc gcggacgtca tgctcgccgg ggcctgcgac
    13861 actcccatca cgccgatcgt cgtggcctgc ttcgacgcca tcaaggcgac caccccgcgc
    13921 aacggcgaac ccgagcgggc ctcgcgcccc ttcgaccgca gccgcaacgg cttcgtcctc
    13981 gccgagggcg ccgcgatgtt cgtggtcgag gagtacgagc acgccgtacg gcgtgacgcg
    14041 cacatctacg ccgagatcac cggctacgcc acgcgctgca acgcgtacca catgaccggt
    14101 ctgaagacgg acggccgcga gatggccgag gcgatccgct cggcgctgga cgaggcgcgc
    14161 accgacgcca cggacatcga ctacatcaac gcccacggct caggcaccaa gcagaacgac
    14221 cgccacgaga ccgccgcgta caagcgcagc ctgggcgagc acgccaggcg caccccggtc
    14281 agctccatca agtcgatggt gggccactcg ctgggcgcga tcggctcgat cgagatcgcc
    14341 gcgtccgcgc tggccatcgg caacggtgtg gtgccgccga cggccaacct gcacgagccg
    14401 gaccccgagt gcgacctcga ctacgtgccg ctcgacgcgc gcgagcggcg gcttcgcaac
    14461 gtcctgaccg tcggcagcgg cttcggcggc ttccagagcg ccatggtgct gcgccacata
    14521 cccggaggtg ccgcatgagc gtcctcgtca ccggcgtcgg cctgatcgcc cccaacggca
    14581 ccggcccgca gccgtactgg acggccaccc tggcgggcca cagcggcatc ggcgtcctca
    14641 gccgcttcga cgtctcccgc tacccggtgc ggctggccgg cgagatccgc gacttcgacg
    14701 cggccgccca cctgcccggc aggctgctgc cgcagaccga cgtctccacc cggtacgcgc
    14761 tggtggcggc cgaccgggcg ctcgccgacg cggcgatcga gccgggcgcc tacgccgact
    14821 acgacatggg cgtggtcacc ggaaacgggc agggcggctt cgagttcacc caccgcgagt
    14881 tccacaagct gtggtcgcgg ggaccggaga aggtgagcgt gtacgagtcg ttcgcctggt
    14941 tctacgcggt gaacaccggc cagatctcca tccgcaacca gctgcgcggc cccagcagcg
    15001 ccctggtcac cgagcaggcc ggcggcctgg acgcgatcgg gcacgccagg cgtacgatcc
    15061 ggcgcggcac gccgatggtg gtgaccggcg gcgtcgactc ggcgttcgat ccgtggggct
    15121 gggtgtcgca gatggccggc ggccggctga ccacgtccga cgacccggcg cgggcctacc
    15181 tgccgttcgg cagcgacgcg agcggccatg tgcccggcga gggcggcgcg atcctcatcc
    15241 tggaggacgc ggccacggcg gccgagcgcg gcgcccctcg ggtgtacggc gagatcgccg
    15301 ggtacgccag caccttcgac ccggccccgg gcaccggccg cccgcccggt ctgcgccggg
    15361 ccgccgaact cgccatcgac gacgccgggt tgacgcccgc cgacatcgac gtggtgttcg
    15421 ccgacgcggc cggcaccccc gacctcgacc gcgccgaggc cgaggcgatc agcggcctct
    15481 tcggcccgca cggggtaccg gtgaccgcgc cgaaggccct caccggccga ctgtgctccg
    15541 gcggaggccc gctggacgtg gtggcggcgc tgctcgccgt acgcgagggc gtgatcccgc
    15601 cgacctacgg cacggacgag gtgcccgagg agtacggcat cgacctggtg cgcggcgccc
    15661 cgcgggagac cccggtgcgg gcggcgctgg tgctggcgcg cggcaggtgg ggcttcaact
    15721 cggcgatcgt cgtccggggt gcgcggggtg cgcggggtgc ggggggtgga cgcgatgact
    15781 gacgggttcg ggcgagtgag caccggggcc gaccggttcg gggaggtcgt cgcgatcacc
    15841 gacggcttca aggaggtcat ggcccggttc ccgaccggcg tcgccatcgc cactgtttgt
    15901 gacgagcgcg ggctgccgca cgggctgacc gtcagttcct tctgctcggt ctccctcgat
    15961 ccgccgctgg tgctgctgtg cgtggccaag tcggcgcgca gcttcccggc gttcgcccgg
    16021 gccggggagt tcgcggtgag tgtgctgcgt gagcaccaca ccgacctggc gaagcggttc
    16081 gcgacctccg acgaggagaa gttccggcgc ggggggctgg tgcgcacgcc ccggggcggg
    16141 ctggtcgtcg acgacgccct ggccgtcgtg gagtgcctgg tggaccagca gcacgacgcg
    16201 ggcgaccacg tgatcgtcgt cggcaaggtc gtcgacaccc ggaccaccga gcccggcgcc
    16261 ccggccgtct acttcaaccg ccgcttcgcc gcgctgagtt catgacccca ctgtccttct
    16321 gccttcgaag gtgacgcaca tggcgttcag caggccgctg cggccgattc ccgacgacga
    16381 gaccctgcgc cgccatctgg tggcgggcgc ggagctcccc gccctgttga tgacggtcgc
    16441 ccatctgacc ggggacgcct cggtgctccg cgacgacctg cgcgcgccgg gctggctgtt
    16501 ccagccgcag ggcggcctca ccgccgtaca gcaggaggag gcccgccgtg tcgccctggc
    16561 ggcgctggcg cgatggcggg ccgaagggcg ggcgcccggg cggcccgacc cggagctgct
    16621 gcgggcgatc accacctggg ccatggggtc cgacaccggc gacctgctgg acctgctcgc
    16681 cgaggagatc gccctgcccg aggacgaccc caaggcgccc gactggacgc tggacgagct
    16741 gagccccggc gccgacttcg acgtcgcggt gatcggggcc gggttcagcg ggctgctggc
    16801 cgcccaccgg ctcgcccagg ccggcgtgcc ggtcgtcctg tacgagaaga acgctgacgt
    16861 cggcgggacc tggttcgaga acacctaccc gggctgccgt accgatgtgg ccagccacct
    16921 ctacaactac tccttcgcgc ccagcaccga ctggccggac cacttctgcc gcagcgagag
    16981 cgttctggag tatctgcggg agttcgccaa ggagtccggc gtggccgagc gcgtccggtt
    17041 cggcaccgag gtgcgcgagc tgcgctggga cgacaccgaa cggcgctggc atctcaccct
    17101 gcgcggcccc gacggcgcca cccgcacggt gacccaccgg gccgtgatca ccgcggtcgg
    17161 ccagctcaac cgccccgccc tgcccgccgt ggaggggctc ggcagcttca ccggacccgc
    17221 cttccactcc gcggcctggg accactcggt ggacctcgcg ggcaagcggg tcgccgtggt
    17281 cggcacgggc gcgagcgcct accaactggt gcccgaactc gccggcgtcg cctccgaggt
    17341 ggtcctcttc cagcgcaacc cgccctggct gcggcccacc ccgcactacc acgagcccgt
    17401 gtccgacagc gcggcctggc tgttcgagca tgtgccgtac tacacccagt ggtaccgctt
    17461 ctggctgttc gcgcccggtc tgcgcggcat cctcgacggc tggatcgtcg accacgacca
    17521 cccgcccacc gaacgcgcga tctccgccct gaacgaacag ctccgcgcct ccctccttca
    17581 gtccatggag gcccagctca ccgacgcgcc cgagctacgg gacaaggtca tcccgaacta
    17641 cccggtcggc gccaagcggg tcctgcggga caacggcacc tggctcgcga ccctcaaacg
    17701 cgacgacgtg acgctggtga ccgcccccgt ggcgcgggag accccgcacg gactggtcgc
    17761 ggacggcgag gagttcgcgg tcgacgtcat cgtgtacgcc accggcttcg aggcctcccg
    17821 cttcctcacc ccgatgaagg tgaccgggga gaacggcctc gacctgcaca cccactgggc
    17881 cggggcgccc cgagcccatc tcggcgtcag cgtgccccac ttccccaacc tgttctgcct
    17941 gtacggaccc aacaccaacc tcgtcggaca gggcggcagc atcgtctact tctccgagtg
    18001 cgccacccgg tacgtcgtcg atgtgatccg gctgctgctg gcgcgcggcg cggacgcggc
    18061 ccaggtccgc gaggacatcc acgacgacta caacgcgtgg gtcgacgcgg cgagcgccga
    18121 ccgtgcctgg gtctggtcga aggtgagcgg ctggtacaag gacggcggcc gttcgtccac
    18181 caactggccc ttctccgccg tcgagtactg gacccgcacc cgtcgcgcgg accccgacga
    18241 cctccatgtc agctgacctc ccagacaggc cagaccagcc agacctgcca gccatgccat
    18301 tcgacgccgc tgggcgtccc tgcgaatcga ggaccggacc catggtggac accacgcccg
    18361 gccggctgac cgaggccgcc cggcagctcg cggacacggc cgtcggcctc gccccggcca
    18421 tgaccgaacg acggcggatc gacgccgacc tggtgaaggc gatgcgcgag gccggcttca
    18481 tgcggcactt cgtgcccgcc cggtacggcg gcgccgccgg gacctttacc gacctgctgg
    18541 ccgcggtggc gaccctcggc gaggcgtgcc cggcgaccgc gtggtgcgcc tcgctgttcg
    18601 cgagcacacc ccggttcgtg ccgtgcttcc ccgaggccgg gcagcgggag ttctgggccg
    18661 aggggccgga caccgcgttc gtctgctcgg tgctgccgtt cggcgaggcg acgccggcct
    18721 ccggcgattc ggggttgcgg gtcagtggcc ggtggccgta catgagcgcc gtggagtacg
    18781 cggactgggt catcgtctgc gccaggctgc ccggggcgga cgggccgcgg ctgaagctgg
    18841 tcgcggtgcc cgtgtcggcg gtctcggtcg aggacacctg ggacaccgtg ggcatgcggg
    18901 ccaccggcag caacaccgtg gtcctggacg acgtcctcgt accggccgcc cgggtcgtcg
    18961 accgggacgc ggtgttcggc gggcggccgg tcgacgctcc cgagacgccc atcgccccgc
    19021 tggccgccgt caacggcctg acgttcgtcg tccccgccct cggcgcggcc cagggcgcgc
    19081 tggccgagct cgcccgctac ctgggcggca agttgaggaa cgtgtcgccc acgccgggcg
    19141 tgcccggacc gggcggcacg ctggccagcc aggagatgac cctggcccgc tcggccgccg
    19201 agatcgacag cgcccgtctg ctgctcaccc gcatcgccga actgggcgac gcacaagggc
    19261 cgttcacccc gcctgtggtc gcgcgcaacg tacgggacag cgccttcgcc gtcgagctgc
    19321 tggtcaccgc cgtcaaccgg atcttccgcg gcgcgggcac cggtggccag gtggcccacg
    19381 gcccgctgga gcggttctgg cacgacgtca acgcggtcgc cacccaccag gccctgcagt
    19441 tcgagcccgc cgcacaccac tacgcgcgcg ccctcctcac caccgacgcc tgacgccacg
    19501 aaggagtacg agcatgacga gcccgccgct ggacaccgcc accccactgg acaccgccac
    19561 cgcacaggcc cccaccaccc cgtccgccga ccggatcatg gagacggcac tggccttcga
    19621 ggcgtcgaag accctgctga gcgcggtcga gatcggcgtc ttcaccgaac tggcccgcag
    19681 gcccgccgac gcggccgaac tgcgcgaccg gctcggtctg cacccgcgcg gcgcccggga
    19741 cttcttcgac gcgctggtcg ccctcggctt cctgcgccgg gtggacggcg tctaccacaa
    19801 cacacccgag accgacgccc acctggaccg ggcgaagccc ggctacggga ccgtcgcccc
    19861 gctgctggag atggcgaact cccggttgtt cggcatctgg aaccacctga cggacgtgct
    19921 gcgcaccggc ctctcccacg acgagtcgaa ggactccggc caggacacct acgacgcgct
    19981 gtatgccgac ccggcccggc tgaagcagtt cctcgcgtcc atgaccggca tcagccaccg
    20041 cgccaacctg cgcatcgccc ggcaggtgcc ctgggaggac tactccacgg tcgccgacat
    20101 gggcaccgcc cagggcgacc tggtcacgca ggtgctgctc gccaacccgc acctgaccgg
    20161 caccggcttc gacctgcccg aggcggagcc ggtgttcacg gagtacgccg aacgccacgg
    20221 cctcggcgag cgtctccgct tcaccggcgg ggacttcttc accgacccct tccccaaggc
    20281 cgacgtgctc accttcggcc acatcctgca caactgggac ctggaccgga agaagctcct
    20341 gctgcgcagg gcatgggagg cgctgcccgc gggcggcgcg gtcgtcgtgt acgacaccct
    20401 catcgacgac gagcgctccg agaacgcgtt cgcgctgctg atgagcctga acatgctggc
    20461 ggtcacggac ggcggtttcg gctacaccgg ggccgagtgc caggagtgga tgcgggaggc
    20521 cggattcgcc cgagcctgga cggaacacct cgtgggaccc gactcgatcg tggtaggagt
    20581 caaggaatga cctctgcgca ggaacagcag gcacagctga aggccaacaa ggaactcgtc
    20641 gccgagtaca tccggctgtt ctacaacgag aaggacttcg accgggcccg ggagctcctc
    20701 accgagggct tcgtcaacca ccaccacgga gtcggcgccg gccgggaccg caccgtggag
    20761 acgttctcgg ccgccgcctc cgcgatgccc gagttctcgc tgaccgtacg gcgcgtcgtg
    20821 gccgaggacg accaggtgtg gacccagagc gtggccaggg cggcgcccgg cgcgcgtccc
    20881 tcggtggtcg tcgacatctg gcggatcgag gacggccggc tggccgagca ctgggacgtc
    20941 ggacaggccg tgccggacgg ctcgaccctc gacgagatga tcgaggacgc ggtggccggg
    21001 gacgccggat gagcgagctg atgcaggccg tcacccagcg ggccttcggc ggcccggacg
    21061 tgctggaagc ggccgaggtg ctccggcccg gccccggcct gaacgaggtg ctggtccgcg
    21121 tccacgcggc cggcgtgaac ccgatcgacg ccctcgtccg ctcgggcacg ctgcccctgc
    21181 tcggcgcccc gcccttcacc gtcggctggg acatctccgg cgtggtggtg gaggtgtccc
    21241 ccggcgtgac ccggttcgcg gtcggggacg aggtgtacgg catgccgtac atcccgcgtg
    21301 ccgcggccgc ctacgccgag tacgccgtcg cgccctcccg gcaactcgcc cgcaaaccgg
    21361 cgaccgtgga ccaccgcacg gcggccgcgc tgccgctcgc ggggctgacc gcgtggcagg
    21421 cgctggccga caccgggctg gtcggcaccg gtacgcgggt gctggtgcac ggcggggccg
    21481 gcggcgtcgg ccatctcgcc gtgcagatcg ccaaggcgcg gggcgccgag gtgatcgcga
    21541 cggcgagcac cgccaagacg gacttcgtcc gggaactcgg cgtcgaccag gtgatcgact
    21601 accgcacacg ggacttcacc gaggaggtca aggacgtcga cgtggtcctg gacggtgtgg
    21661 gcggcgagac cgccgagcgc tccttggacg tcctgcgtcc gggcggcgcg ctcgtgacca
    21721 tcgtcgagat gcgcaacacg gacctcgccg cccgggcgga gacccgcggc ctctccttcc
    21781 acggcgtgac cgcggaaccc gaccacgtgg gcctcaccgc cttggccgac ctcgtcgact
    21841 ccggccgcct gcgcccgcac atcgcccagg cgttgccgct gtcccgggcg gccgaggccc
    21901 accggttgct ggaggcgggg acgctgccgg ggaaggtggt gctgcaggcg gcctgacgag
    21961 cgggcgcgcg gccggggcgg cgtgtccgcg ccgagccgga agcgtgcgtg cggggtggtc
    22021 ggggccgggc acccggacct cccgatcacc gccttcggtg ccttgtgcac cggcgcgctc
    22081 ctcgccgtgc cgctgcccgc acatcgcgga cccgtggacg cgatggtgcg ggtcccgccc
    22141 cgccaccagg ggcgccggga tgcggcgacc gaggtcgcgt gctcaccgcc cgtgccgacc
    22201 cggaggcacg gaccacccct cccgggcctg cccgccaact gctccccatc ccaagaacgt
    22261 tgacccaccc cacccacacc agcagaatga gcccgcatcc gtgagagcgc tctcaaggct
    22321 tggtgaggga gacccatgac cggcatgacc gacgacaggc aaggtccggc gttcagtcgg
    22381 cgcggactca tcggggccgg tgtcggcgcc gcagtgctcg ccgtggccgg agcgggtgcg
    22441 gcgcacgccg gagtgggctc cgcgcggcgg cgggggcatg acttcctggc cgccgccatg
    22501 gacgcctacc ccgaccacgg cgccgtccgt ctcgcccaga gctacaccga ccaggccggc
    22561 ctcttcagca ccgccttcac ctacgacaac gcccttgcga tcctcgccca cctcgccgtc
    22621 gggaacgcgg acgggcgggc ccgggccgtc gtgctcgggg acgcgttgct gtacgcgcag
    22681 gggcacgacc cggtccatga cgacggtcgg cttcggcagg cctacaacgt cgggccgtac
    22741 accttctacg acggctcggt gcagccggac gggttcgtgc gggcggacgg cagcgccaac
    22801 gtcggtacgc agttcgggtt cacggggacg gccgtcgggg acatggcctg ggccgggatc
    22861 gcgctcggtg cgctggcccg gcggacgggc gggcggcggt tcctcgacgg tgccgtgcgg
    22921 gtcggggagt ggatcgagcg gaacgggcgc accgacgaac ccctcggggg atacaagttc
    22981 ggcgtcaacg gggcgaacga gaagcttccc ttcacctcca ccgagcacaa caccgacctg
    23041 gtctgtctgt tcgggcgcct cgcccggctc accggggacc gggtgtggct ggagcggcgc
    23101 gctcgggccc gggagttcgt cgggaggatg tgggaagcgg acggcgggtt cttctacacc
    23161 gggaccaacg acggcatcag catcaacacg tcccccgtcc ccgaggacac ccagacctgg
    23221 acccacctcg ccctcgactc ccgcgcgcac gcctcctcgc tggactgggc cgcgcgcgag
    23281 ctggccgtcc tcgaccacgc cgggcggcgc aacagcacgg tgccggcggg gcagtcgtac
    23341 gaaggtgtca ccttcagctc cgccagtctc ctcgcgaacg aggacgcccc gatcgccgac
    23401 tcccagccca ggcccgaccg caacggcgtg tggttcgagg ggaccgctca tctcgcgctc
    23461 gccctgcggg agcggcaggg gcggggggac gaggcgcggg cccggcggct ggtcgagtcc
    23521 atcgagcggg ctcaggatct gctcggggcg ggacagagcg tgggtgggcg ggcgttgccc
    23581 ggacggtccg gggtcgtggc ggcgagcagt ccgctcgaca ccgggttcgg gttcggctac
    23641 tacccgtacc ggcacacggg ggcgaccgcc tggtacctga tggcggcgac gcgcttcaac
    23701 ccgttgcggg tctgaacgcg caccaccctg ttgcggggcg ggcccgggat gccgatcgcg
    23761 ggcccgctta cagtggagcc gtgtcctcag gaaacagcgt ggtggcgcgc aatgtgcgcc
    23821 tactcagaga gcagcggggc ctctccctgg ccgaactggc ccggcaggcg gggctggcca
    23881 agcagacgct gtccaagctg gagcagggca ccggcaatcc cacggtggac acgctgttct
    23941 ccatcgccca ggcgctcggc gtgccggtga cccggctggt ggccgagcgc gagcaggtga
    24001 tgaccgtgca gcgcgccgac gaggtcgtct ggcagcagca cggggggtac gagagccggt
    24061 ccctggacca tgtgtacggg tccggtgtca tcgagaacta cctggtgcgg atagcgccgg
    24121 acgcggacgg cgcgggcacg gtgtccgagc cgcatccggt gggcaccctg gagcatctgt
    24181 acgtgatcag cggacgggtc agggtcgggc cgtccgacag ccctgtcgag ctgtcgtccg
    24241 gtgacttcgt gcggtacccg ggggaccggc cgcatgtgta cgagtcgctg gacggggaga
    24301 gcctggtgca catcgtggtg agtgtgccgc gggtgcagcc cgggaccggc ggtacgaccg
    24361 tggcgcggac ccatgggaac ggcctgcgct gaaaccggcc gcggggtgtc aggccgcggg
    24421 cgggcttccc agtcccgccc tggccgtggt gaccgcccga gccgcctcgt acgccacccg
    24481 ccgcagcgcg ggcgcgtagc gggccgggtc gaagcggtgg cccgcgcccg cgaccgagag
    24541 ggccgccacc ggtcggccgc cggggcccat gaccgggacg gcgacgcagg tcaggccgag
    24601 ggtggcctcc tggcggtcgt aggcgatgcc ctcctggcgg atgcgccgca gttcggaccg
    24661 gaaggcggtg gggtcggtga gcgtgtattc cgtacggccg tgcaggcccg cctcgacggc
    24721 cgcctccgcc gcgtcgtggt cgaaggccag cagggccttg ccgacgcccg tgcagtacgc
    24781 gggcatccgg gcgccgatac gggaggggga gcgcgtcgga cggtggccgt ggatcttgtt
    24841 gacgtacacg atctcggtgt cgtgcaggac ggcgaggtgc acggtctcgt gggtcaggac
    24901 gtagaggtcg gcgaggtgcg ggagcaggcg ctcgcgcagg agcacggtcg tcgggccgta
    24961 gacccgggtg ccgatgtcga agagctgggc gcccaggcgg tagtcgctgc cgacccgttc
    25021 gaccaggtcg ttgcgctgga ggatggccag cagtcggaag gcggtcgact tggtcaggcc
    25081 ggtgcggcgg gccagctcgc tgacgccgag ttcatggtcg tgctcggcca gctgcttcag
    25141 caggatcagg gccttgtcga ccgcggtctg ctgttccgag gtggaggggg cggtggggga
    25201 aggcatgggc atggtcgtct ccctgggcgc ctcaggcgac catcttgatg gacgtgcgtc
    25261 caccataggt gaccgtttcg gcgctgtaaa cggcccggac acgagctgcg ccgggccgtt
    25321 cgcagcaccg cgggacacgg gtcagatctc gaactcctcg tccctcgtct ccggcagcgc
    25381 cagcacgcac agcaggctga ccagacacag cgcacccgcg tacaccccca gcaccagcgg
    25441 cgacttccac tggctgttca gccacgtggc gaccagcggg gcgaagccgc cgccgagggt
    25501 gttggcgagg atgaaggtcg ccgaggcgcc ggtgtagcgc agccgggccg ggaacagctc
    25561 cggcaggaag gccgcgatcg gcgagaacat catgatgaag a
//
