LOCUS       BGC0001392             25209 bp    DNA     circular BCT 24-DEC-2013
DEFINITION  Chitinophaga pinensis DSM 2588, complete genome.
ACCESSION   BGC0001392
VERSION     BGC0001392
KEYWORDS    .
SOURCE      Chitinophaga pinensis DSM 2588
  ORGANISM  Chitinophaga pinensis DSM 2588
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 9127347)
  AUTHORS   Glavina Del Rio,T., Abt,B., Spring,S., Lapidus,A., Nolan,M.,
            Tice,H., Copeland,A., Cheng,J.F., Chen,F., Bruce,D., Goodwin,L.,
            Pitluck,S., Ivanova,N., Mavromatis,K., Mikhailova,N., Pati,A.,
            Chen,A., Palaniappan,K., Land,M., Hauser,L., Chang,Y.J.,
            Jeffries,C.D., Chain,P., Saunders,E., Detter,J.C., Brettin,T.,
            Rohde,M., Goker,M., Bristow,J., Eisen,J.A., Markowitz,V.,
            Hugenholtz,P., Kyrpides,N.C., Klenk,H.P. and Lucas,S.
  TITLE     Complete genome sequence of Chitinophaga pinensis type strain (UQM
            2034)
  JOURNAL   Stand Genomic Sci 2 (1), 87-95 (2010)
   PUBMED   21304681
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9127347)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Chitinophaga pinensis DSM 2588
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9127347)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Metadata-START##
            Organism Display Name :: Chitinophaga pinensis UQM 2034, DSM 2588
            Culture Collection ID :: DSM 2588, ATCC 43595, LMG 13176, UQM 2034
            GOLD Stamp ID         :: Gi02244
            Funding Program       :: DOE-GEBA 2007
            Gene Calling Method   :: Prodigal
            Isolation Site        :: Pine litter in Australia
            Isolation Country     :: Australia
            Oxygen Requirement    :: Aerobe
            Cell Shape            :: Rod-shaped
            Motility              :: Motile
            Sporulation           :: Nonsporulating
            Temperature Range     :: Mesophile
            Temperature Optimum   :: 23 - 24C
            pH                    :: 7
            Gram Staining         :: gram-
            Biotic Relationship   :: Free living
            Diseases              :: None
            Phenotypes            :: Biomass degrader, Chitin degradation
            Energy Source         :: Chemoorganotroph
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version               :: False
            Run date              :: 2025-08-15 19:17:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start           :: 6791519
            Orig. end             :: 6816728
            ##antiSMASH-Data-END##
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082984
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
FEATURES             Location/Qualifiers
     region          1..25209
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /subregion_numbers="1"
                     /tool="antismash"
     cand_cluster    1..25209
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25209
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15209](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15209)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     subregion       241..22166
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="ribosomal"
                     /subregion_number="1"
                     /tool="antismash"
     gene            complement(244..1116)
                     /locus_tag="Cpin_5317"
     CDS             complement(244..1116)
                     /codon_start=1
                     /db_xref="InterPro:IPR000005"
                     /inference="protein motif:PFAM:PF00165"
                     /locus_tag="Cpin_5317"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type; SMART: helix-turn-helix- domain containing
                     protein AraC type; KEGG: csa:Csal_0346 transcriptional
                     regulator, AraC family"
                     /product="transcriptional regulator, AraC family"
                     /protein_id="ACU62748.1"
                     /transl_table=11
                     /translation="MKRIDKYEGLYGDRDAKPDAGYIFSELLGTRSWKFDWNIEPHIHP
                     SIYQLFFFEEGKLTFFEADSQRELQTPCMLLIPPMALHGFRYETVAGGRILTLSDVMLD
                     TLFPESALLAPMLTTIRCFADFNGPYSAEDIVALIKAVDKELFGDLPEKKVMLRICLQQ
                     LFLAVYRLWQDQQSGNTLSDNHSLGYFRKFQQRIREEGLRYTIAQFAAELGITTVHLNR
                     ICREVVGKSAGQLVHDHILEEAKKYLTYTSYTVSEIAYLLNFEYPNYFARFFRKHAGVS
                     PKEFRTIRN"
     sig_peptide     1280..1387
                     /locus_tag="Cpin_5318"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.954) with cleavage site probability 0.522 at
                     residue 36"
     gene            1280..2488
                     /locus_tag="Cpin_5318"
     CDS             1280..2488
                     /codon_start=1
                     /db_xref="InterPro:IPR004812"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="protein motif:TFAM:TIGR00710"
                     /locus_tag="Cpin_5318"
                     /note="TIGRFAM: drug resistance transporter, Bcr/CflA
                     subfamily; PFAM: major facilitator superfamily MFS_1; KEGG:
                     pca:Pcar_2625 Bcr/CflA subfamily drug resistance
                     transporter"
                     /product="drug resistance transporter, Bcr/CflA subfamily"
                     /protein_id="ACU62749.1"
                     /transl_table=11
                     /translation="MQNKQHTIIILILGLLIALSPFSIDMYLPAFPAIASALKTDIAHV
                     GYSLTSYYAGLCAGQLIYGILIDRLGRKKPLYAGLLIYLTAAFACAFSLNINMLVAVRL
                     FMALGGCVGMVTARAIVRDLFPPKDTARVLSLLVLVMGIAPIIAPTIGSIVNTIAGWRW
                     LFGVMALIALALLIATYTLLPETKTPDPDVSLRIKDVLPEYIAVLKNPAFLVYTLAGGI
                     SYAGLYAYIAGSPFVFMTRFGFSDTAYSWAFAFNACGLISGSQINRLLLNRYDSIHISF
                     YAAILLFITGLLLLISTALGIAGAPMTLCFTFLFLFCLGFLNPNTTALALRPFTAAAGR
                     ASAVLGSIQMIAGVIASWTVNFFFNGTANVMAAVMFGCTALTLFLLVFFTGRRRTKQDL
                     QPA"
     gene            2552..3385
                     /locus_tag="Cpin_5319"
     CDS             2552..3385
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5319"
                     /note="KEGG: hypothetical protein"
                     /product="hypothetical protein"
                     /protein_id="ACU62750.1"
                     /transl_table=11
                     /translation="MRKILYAVPVICLFACSPRLQPSPPATLTPLSDTAFVVVLEEADR
                     FSGGQKAGVIHSSDNTIAPACTYEDIISRMQQAARTRGANLIKITSYSTPRAGNNCEQI
                     TANLYKVGHPRSYERKFTWHPARTLSWEDYKGTPSTIREANVGARTSCRFGIKIDTGST
                     PGKARVIVTSEFICYQSSVRPNQQTPSLLAHEQLHFDLCEAYARSLRKTLAATNLTPAN
                     VARISKDAFLQTYQLYREQQALYDAETEHGLNPEAQVRWKKKITDALNGLQAYQQ"
     gene            3399..3797
                     /locus_tag="Cpin_5320"
     CDS             3399..3797
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5320"
                     /product="hypothetical protein"
                     /protein_id="ACU62751.1"
                     /transl_table=11
                     /translation="MSAIKYFLFIFCNIVTFVYLYAMCETQHTFMRKLTAFLLLSVLMY
                     VQGLKTFHRHDVSTVKYHAEASDLFFKSTHECAICDYHLCKDAVLPSIPVVQQTPFYYI
                     VTDVCDTTDRSVNLSDTVSGRGPPARFI"
     gene            3849..4553
                     /locus_tag="Cpin_5321"
     CDS             3849..4553
                     /codon_start=1
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF00005"
                     /locus_tag="Cpin_5321"
                     /note="PFAM: ABC transporter related; SMART: AAA ATPase;
                     KEGG: bbt:BBta_3361 putative ABC transporter ATP- binding
                     protein"
                     /product="ABC transporter related"
                     /protein_id="ACU62752.1"
                     /transl_table=11
                     /translation="MLQAIALTKEFGRHTALHALDLTVQKGEIFCLLGPNGAGKTTTVN
                     CFLGFIAPTSGRALVNGIDVAQQLPQARQHIAYIPETVMLYAHLTGLENLVFFDSLTGH
                     HHSREHYTTLLLKAGLQENAIHRRVKTYSKGMRQKVGIAIAAAKNAQVLLLDEPTSGLD
                     PHASNEFSDLLRRFSEEGRAVLMATHDLYRAREVASRIGIMKNGRLIADMEADAVDHYT
                     LENIYMEHMRTV"
     sig_peptide     4577..4684
                     /locus_tag="Cpin_5322"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.945) with cleavage site probability 0.901 at
                     residue 36"
     gene            4577..6007
                     /locus_tag="Cpin_5322"
     CDS             4577..6007
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5322"
                     /note="KEGG: xca:xccb100_3903 putative ABC transporter
                     permease"
                     /product="hypothetical protein"
                     /protein_id="ACU62753.1"
                     /transl_table=11
                     /translation="MYLLLTTKEWLGGLRTYALPAVLLSLLVLLGIAFAGTHSRSEQIS
                     RNRSAANAHFRQQWEQLKTSDPHSAAHFGTYLFKPVMLLSNFDSGLETVTGTSMRIEAH
                     VQHTMAAPVLRPADIYTRFGSLTIASVLQLFFPLFIIFSCYNSYTQEKTNGTLRLLLIQ
                     GATQSVILKSKTKYYLIAVNIMLLASLLIYLPALLFSGTTTTTTDQTTLLSILCLIIAY
                     SSYCSIFVMIAIAISAIAKNARQSLLLLTGCWLIWNILLPRLGAGIAGELHPLPSQYQQ
                     QEKMEKAIKMGIDGRSSREERIQQLTDATLKQYHVKSADQLPVNLHAILLQSSEDYAQM
                     VYDIYTAKTDSIITLQNRYSNYLALVDPYLAIRNLSMALCGTDYLHQQQLDRAARQYRN
                     DFIRRLNNELAYGGSKTNDSHWKVNASFYSSIPPFHYKPPALIQVLASQWMMIAALLLW
                     LAISICLLQIIARHAGIE"
     sig_peptide     5991..6119
                     /locus_tag="Cpin_5323"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.974) with cleavage site probability 0.550 at
                     residue 43"
     gene            5991..7439
                     /locus_tag="Cpin_5323"
     CDS             5991..7439
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5323"
                     /note="KEGG: dac:Daci_4459 hypothetical protein"
                     /product="hypothetical protein"
                     /protein_id="ACU62754.1"
                     /transl_table=11
                     /translation="MLVLNNKINSWKQIIRFELHTLLRTGTLPALLLIILSAGTAAVLF
                     GHHIRVHQLNTLDSIRIDYSIQYDKLYKGLSADTSTPEGKAAYISASHPAVIDYRLHKT
                     VAHPPAAFSGLSVGMSDMTRYYVPVTVKETYVPVEEKINNPLHLLTGNFDVSFLIIYLL
                     PLALICTSYNLLAQEKEQGTLSLLIIQKGGIADLLFLRLLIRYAVVLCCVLLLTLLSIT
                     LTQTASFADTLSWLLISAAYLAVWTGIIWLLLSWNAGTAVSLITMLCAWMFLLVVLPSL
                     FNFRLNHADTDENTAILASLQREIEWDTWDMPQQQVLDSFYAVYPVYRNSQAYDTSASS
                     TRRMMAYYDLVSRRMQRLTAQATINRIQGIQQINHSYQYNPAVYTQALLNSVAHTDIAD
                     YAYFQQQTALFRQQWKSFLYYYHFNDKKFSADDYRILPVYHPSYRPDSRKLQLQGVCHL
                     LLLAGGLLLTGTFLLRKNHTGHRI"
     sig_peptide     7465..7527
                     /locus_tag="Cpin_5324"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.930 at
                     residue 21"
     gene            7465..9597
                     /locus_tag="Cpin_5324"
     CDS             7465..9597
                     /codon_start=1
                     /db_xref="InterPro:IPR000531"
                     /db_xref="InterPro:IPR001484"
                     /db_xref="InterPro:IPR010105"
                     /db_xref="InterPro:IPR012910"
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="protein motif:TFAM:TIGR01783"
                     /locus_tag="Cpin_5324"
                     /note="TIGRFAM: TonB-dependent siderophore receptor; PFAM:
                     TonB-dependent receptor; TonB-dependent receptor plug;
                     KEGG: ppg:PputGB1_0701 TonB-dependent siderophore receptor"
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="ACU62755.1"
                     /transl_table=11
                     /translation="MKKSLPIPFSLCLLAISAQAQQKTDSLRKQHLKEIEIMEKKKNMR
                     TDSMSPVLRMEGRMLEIPQNITGVTADLIREQGGLEMKDIIRNASGVKIGYNSSVFDAS
                     ATVMMRGFYTDTYVNGMPQRSTMGALTDDAAFIERVDFVKGPAGFLISSGDPGGSVNIT
                     TKTPRQQRVRQLELSGGSFGFLRGSLDLGSAVKEKGFSYRLNGAYQQQQSFLDFLKTRK
                     YVASPVIQYNFSRRTSLLAEYNFIHMLSDGGSSVTKIGTESEVLKDRIGNNYAGDPNLP
                     QSGSKSQSIRLAFEHRFNDHLRLTIQSKYTVNSTAVWYLISDNYSLINFDSTNITRRLP
                     VNNSITGRVAAVQAYLSGNLKTGQHITHNFVAGLDYNYSKDNYVNAYGQYAFTFDRTHP
                     QYGLHPDSVKMLGKPALIVRENNWTSAFAYNTTRIHTNWLFNYGGRLTINTPVTTNPRQ
                     PQKDETAFSPRLGITRLLNNNMAVYALYDQSFIPQSGVNANGQRFDPQRGNSLEAGAKK
                     EWFQHKLMTSIAGYRILKNNLLVSDLEHPGFRRQIGQVTSTGAELDITGRIADRLSISA
                     NYSYTHAIVSKDSRKENEGNKLAFTPEQVINSWIQYGIPLKAGSRLSLSLGHNTVTKTA
                     TYTPGFDLKGYTKFDGGIAYTHGKWYLRVVADNLTNKRYFSSGDMLVGSVYEGVKTYYY
                     IEGAPISFKAFAGIRL"
     gene            9666..9854
                     /locus_tag="Cpin_5325"
     CDS             9666..9854
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5325"
                     /product="hypothetical protein"
                     /protein_id="ACU62756.1"
                     /transl_table=11
                     /translation="MKDNQVTQIKLSIDDLKIDSFVTSIDSEMNMRLAGGLAGQSHPTH
                     TVATDDEGHLCTTIICA"
     gene            complement(10001..11845)
                     /locus_tag="Cpin_5326"
     CDS             complement(10001..11845)
                     /codon_start=1
                     /db_xref="InterPro:IPR007822"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="protein motif:PFAM:PF05147"
                     /locus_tag="Cpin_5326"
                     /note="PFAM: Lanthionine synthetase C family protein; KEGG:
                     mxa:MXAN_2857 putative lantibiotic modification protein"
                     /product="Lanthionine synthetase C family protein"
                     /protein_id="ACU62757.1"
                     /sec_met_domain="LANC_like (E-value: 2.1e-48, bitscore:
                     155.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMPAVNLKDEQVIAAALLDLAEKLLPAIQPDTIAADLHNGAPVD
                     LFNGKAGIIVFYLRLAEYDPGYLPVCTAAADVLLYHPAISEQAFFTLYTGATSLVYLCI
                     QLYEATGDQRYLERGLALVAHYQEGILQKVVQDDFISGHAGNLLVLTQLHAYTKDDSLR
                     VLIRQLADKLVAHARIAAQGLRWGHLKRSYDCLTGLSHGAAGIAHALLQVAVYFEDEGL
                     RYLAMQSWAYEMKYYDPVFKNWLDLRLTSTHLQETDIMGWQIADFRRYISDVNAWAHGA
                     AGIGLSRMYAWGISGEAHFAAESEWALTRCLQDADTLMRGDFTLCSGYGGIGMFLMEAG
                     AVFDRPVLRQTAQRIAMAAIRYFEAHGTYNSYIKDAQDDPGLFSGLAGVGYLLVSVLLP
                     YKENTVMAPLISRNRKDVPLYEKGEVKRALFSRYYEKSLQQYPAALIANDMHELEQLLE
                     KEMGDQDCFRYEKSLADVWRSHSGWLCYQQRNRLLEKRNSYLLQENDRVLLQTVFVPVP
                     ELMVCATDHAWHGEAVTNQQESTGYYYVHIAHVQGVSTFPVNQFTAMLLKAFEGQLPLL
                     QLITDIIYPQVDVGMAALQEAVLSQVRVFLRQCMITQK"
     gene            complement(11814..12650)
                     /locus_tag="Cpin_5327"
     CDS             complement(11814..12650)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:Prodigal:1.4"
                     /locus_tag="Cpin_5327"
                     /note="KEGG: bce:BC5083 lantibiotic biosynthesis protein"
                     /product="hypothetical protein"
                     /protein_id="ACU62758.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.8e-26, bitscore:
                     82.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRNWLSAHLFYRGDLRFLLLEMVLPFLRDTPYRGFFIRYGEGGP
                     HIRLRLLPGSADIALIQSQLIAAGRVIEGLTIQFIAYEPEIARYGDEDSIAWAEEQFMC
                     SSAYVLDVLNNKREWDASGALLEALKMNMAIACALDVPAHEMIATCRQFIDQWLPRLYD
                     RSKFAAEQKQYYTTQLDHRFSHYAPLLLPATATLWEALHTGKATPRLQAFMQSNRRIFQ
                     EYSRLGFDDHSMRDITGSFMHMGHNRLGVSNLDEAYIMFFTLKCLENVYAGGKSER"
     gene            complement(12654..15209)
                     /locus_tag="Cpin_5328"
     CDS             complement(12654..15209)
                     /codon_start=1
                     /db_xref="InterPro:IPR006826"
                     /db_xref="InterPro:IPR006827"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="protein motif:PFAM:PF04737"
                     /locus_tag="Cpin_5328"
                     /note="PFAM: Lantibiotic dehydratase domain protein; KEGG:
                     bce:BC5084 lanthionine biosynthesis protein"
                     /product="Lantibiotic dehydratase domain protein"
                     /protein_id="ACU62759.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.6e-42, bitscore:
                     134.3, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALSIFPHILVRYAGMPLSVLHTAKVKDIADYLQETAQSAKQLAA
                     QKEAVCDLLYTAISQSTDDKERRQLLQLKRDIFNDKRPVKLPAFVPETMKAYLQQLVDR
                     EKEEVQWRDYFEEKHTAARRELQGYVQDEALRKGILLSSPVLYEQLDSFALADSRQFKS
                     RTLKNEHSLIRYISRMAAKTSPFSTFTYTGLGKMGTPDAAAATPEIHSDIRLHNGLFSY
                     IRLLIIYHPVLNEIITLRLNVTATIIQEELQFLVNYFNVEAFQRLPARNLPLWLYHQLQ
                     DREAIVTLGGLTDQLCSQIADTDRSAIKSFLLQLVFNGLLEPGIGCAGIDPDWDGQLLQ
                     FLTPYADQQAVALLLKMLSELQQTKTAYAIATADRRHRLLLETAGSLEDVFRVLQEEAG
                     LPDEMPLKEGVFELFRFQARRFLPQDIFYEDAFTDRADILPATALSVFTREINQLCTLL
                     APLDALAEERAHMQRFFVQHYDEGAEVPVTRFYHDYYLQEKKQATDQQAKKDIKEIHLP
                     DTLQLVLEQDTVHITPAIEVIPDNNSAGAFVQFYQEGSHIKGVINALLPGMGKVAGRFL
                     HLLPPVVTADFRTWNKNLYTDHLLLELNDGSAFNANIHPPLLPYEVAMPGGNNIYAAEA
                     RVSLKDLVVKHEPATRTLSLFHKGQNKPVYAFDLSLESFYNRSHFYRLLAHFNTVQRVP
                     LRAMITALDRKHATIYPPNERIQVKPRITFGEQVVLRRKGWLLQTAFIPLCGNEESAAD
                     YFKRLNTWRIENDIPEQCFLFLRSAYIPVVNGQKSQLQRDDYKPQYMDFSHPLLATLFR
                     KVLSRAGEWCYLEEMLPAATHVAADGGVVKEYLLHWYNR"
     gene            complement(15243..17450)
                     /locus_tag="Cpin_5329"
     CDS             complement(15243..17450)
                     /codon_start=1
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005074"
                     /db_xref="InterPro:IPR017940"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF00005"
                     /locus_tag="Cpin_5329"
                     /note="PFAM: ABC transporter related; peptidase C39
                     bacteriocin processing; ABC transporter transmembrane
                     region; SMART: AAA ATPase; KEGG: eba:ebA1666 fusion of ABC
                     transporter-type transmembrane and ATP binding protein"
                     /product="ABC transporter related"
                     /protein_id="ACU62760.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.6e-34, bitscore:
                     108.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQFLFPRKSFPFFRQADAMDCGPTCLQMIAAWHGKTYPLQYLRR
                     QCKISRQGVTFADLITAGEQLGFNTLSAELPFTVLAAKAPLPCILHWDRQHFVVLYRLT
                     EHKVYVADPALGRRIRYTIPEFMEAWQLADKPGFGRALFLEPTAAFHAATEVKAPVTDL
                     RTLWPYISSHRRKLIPVGVSLLIAAVLSFIVPLLTEAIVDRGINKQDIPILLLICAGQL
                     SLFLGKQVTDFFRARLLLTLGAQMSIMMLEAFLLKLMRLPFSFFDNRQSGDNMQRVTDN
                     QRVEDFLTTSAVSFVMSVMILLVMGGTLLYYNWLIFILFAIGAAVGVLWTGAFGEKRGR
                     LDQKRFRVLAANQDTLLEIFSAFQEIKLTGSERLKINQWTRLQQQSFTVKLESLKLDQF
                     IQGIALFINETRNVIITCFTAILVIKGQLTLGEMLAITYICGQLNAPVAQLAEFIRAMQ
                     NTKFSLQRIAEVHHEQDEDPPQENTITEDMGGRDLHLSGVYFQYGNKHSPLVLNNVNLS
                     IPAGKMTAIVGMSGSGKTTLLKLLLQFYDPTQGTIFAGDQSFTAITAQDWRSQCGAVMQ
                     DGYVFRDTIANNVYGGEADRDVERMMKACRMANIHDFFAAMPFGYDTMIGKDGYGLSEG
                     QTQRLLIARLIYRDPAYIFLDEATNSLDASNERAIINNLHEYFVGKTVVVVAHRLSTVK
                     HADQILVMDKGMIVEAGTHETLTIAAGAYYRLIKNQLELGR"
     gene            complement(17593..18882)
                     /locus_tag="Cpin_5330"
     CDS             complement(17593..18882)
                     /codon_start=1
                     /db_xref="InterPro:IPR003423"
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF02321"
                     /locus_tag="Cpin_5330"
                     /note="PFAM: outer membrane efflux protein; KEGG:
                     gme:Gmet_3465 outer membrane efflux protein"
                     /product="outer membrane efflux protein"
                     /protein_id="ACU62761.1"
                     /transl_table=11
                     /translation="MRKVIIISLLSLAGLQSYAQEVSSDLKELINKSFTYFPRFSELEQ
                     SVKTEEERVTLAKANGLPNLTCSAGYRYSHPVSEMTIPINGQLSTFKIMPNSNYNTGLN
                     ASYVLWDFGVVKANVESAKRAVQYAKDNIEYNRAQMAYQVAVIYYQIVYLQKAIAIQDS
                     VLAFLKANKEDTEIKLKHGDALRYDVLSIQSTIDQENNTRIDLENSLLKQYNLLQYSTG
                     STAANGKDFDFMQANENKQEALNIAQQHNPEYTLLKDRISQSEAGLDISKKAGLPSLSL
                     SASTGFANGYMPDLNQFRYNYAGGVTLSVPIYQGARARRQRSLAQSQLKEANLGMQTLN
                     NTVQNDIKQAYTDIESNQSRLVNAMEQVEEAKEAQKLAQSRYRNGTGTNLELTNASTNV
                     QRAERSTLQYTYQLCLARLELARVLGTKYW"
     sig_peptide     complement(18823..18882)
                     /locus_tag="Cpin_5330"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.995 at
                     residue 20"
     gene            complement(18905..20482)
                     /locus_tag="Cpin_5331"
     CDS             complement(18905..20482)
                     /codon_start=1
                     /db_xref="InterPro:IPR001411"
                     /db_xref="InterPro:IPR001958"
                     /db_xref="InterPro:IPR004638"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="protein motif:TFAM:TIGR00711"
                     /locus_tag="Cpin_5331"
                     /note="TIGRFAM: drug resistance transporter, EmrB/QacA
                     subfamily; PFAM: major facilitator superfamily MFS_1; KEGG:
                     glo:Glov_1631 drug resistance transporter, EmrB/QacA
                     subfamily"
                     /product="drug resistance transporter, EmrB/QacA subfamily"
                     /protein_id="ACU62762.1"
                     /transl_table=11
                     /translation="MAVNKFTRVIIVITTISAAIMELIDTSIVNVALNNISGNLGATLE
                     DTSWVVTAYAIANVIVIPMTGFLSRYFGRKNYYLTSIIIFTLASYMCGSSSSLWMLVFW
                     RFIQGVGGGALLSVSQGILFDAFDPSEKGKASGMFGMGIVIGPTIGPILGGYIVDNYAW
                     PLIFDINIPFGIVACLLTWKFIDKKENEYNIDRKSIPIDYIGVLSLSAGIGALQYILEK
                     GQSDDWFEDSTIRIMTAIAVAGLAAFIWWELKTKTPIINLRVLKSRNLIGSNVLTFVCG
                     FGLFGSVYLFPLMVQRVMGYTPTESGLSMIPGALVTIMVMPFIGASLGKGVSPMFFVVT
                     GFGLFILHGYTSAQATPDADKWWFMYTQIFRGVGTACLTVPLLSQAVVGLKPQDMPYGI
                     SLNNMFRQIGGAFGIAIMNTYSTQRFAVHRSDLVSNLQGNNPLMNERVAGVAQGLISKG
                     VNPIAANAHGAWSNLDYAITRQAQMLAYLDGFLLVSVFFVCTIPFMLLLKIEKMDAETR
                     ARVAAEAH"
     gene            complement(20502..21545)
                     /locus_tag="Cpin_5332"
     CDS             complement(20502..21545)
                     /codon_start=1
                     /db_xref="InterPro:IPR006143"
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="protein motif:PFAM:PF00529"
                     /locus_tag="Cpin_5332"
                     /note="PFAM: secretion protein HlyD family protein; KEGG:
                     vfi:VF_0878 EmrKY-TolC multidrug resistance efflux pump,
                     membrane fusion protein component"
                     /product="secretion protein HlyD family protein"
                     /protein_id="ACU62763.1"
                     /transl_table=11
                     /translation="MTQEKTQPSKGPVKFIVLGVAGIAILYFGGKKIMHAYTHESTDNA
                     QIESNAIPVVSRVGGYIDTFALQDYQSVKGGQLLLTIDDKEYKIAVQQAEADLSAAKAD
                     LIFAEAQITNIGSDKNVADAGVSVEQVNLEKATRDLARDQALFNDGSITQHQLDNSQSA
                     YKVALSQLESSRKRVSQVVTQHGTANAQIEKAKANVALKEAALESAKLKLSYTQVIAPV
                     AGRIGKTNLQKGQLVQAGQQLFSVVNNERYWIVANFKETQLEKMKIGQVVKVEVDGYPD
                     KEISGKIVAFSDATGAKFSLLPPDNATGNFVKVTQRVPVKIEIDRAEELKSILKAGLSV
                     TVDVQVD"
     gene            21699..22163
                     /locus_tag="Cpin_5333"
     CDS             21699..22163
                     /codon_start=1
                     /db_xref="InterPro:IPR000835"
                     /inference="protein motif:PFAM:PF01047"
                     /locus_tag="Cpin_5333"
                     /note="PFAM: regulatory protein MarR; SMART: regulatory
                     protein MarR; KEGG: transcriptional regulator, MarR family"
                     /product="transcriptional regulator, MarR family"
                     /protein_id="ACU62764.1"
                     /transl_table=11
                     /translation="MAMKEKNKSTDKDDNLFATLYILKRAMDDWGSRNIANWGYENFNI
                     TYMPFFMNIGNEGVSNNEIAEKMRVTKQAASRIVRELEASGLVRGEKSDSDGRSVKLYL
                     TEEGHKFQEIAKNEAKILRKEYVKVIGRERYETAVDVLKELIAFHENLLK"
     gene            22591..23163
                     /locus_tag="Cpin_5334"
     gene            complement(23560..24321)
                     /locus_tag="Cpin_5335"
ORIGIN
        1 aactggcttt ctaaggttac atctttacac ttatatccac ctaatgaatt ttctggcaga
       61 acccgagtat gcacttttac agcataataa ggggccagat cagataaacc tgcaattgaa
      121 attattctcc ttttaaaaaa agaggggggc ttgcttttat aatagcagta agcccctccc
      181 atctatattg agtttgaaag gaataaaggg gtaatcccaa ttttaaccgg acactataga
      241 ttcctaattc ctaattgttc tgaactcctt cggagaaact cctgcatgct ttctaaagaa
      301 cctcgcaaag taattcggat attcaaagtt gagcagatag gcaatttctg aaacggtata
      361 agaagtataa gtcagatact ttttcgcttc ttctaaaata tgatcgtgta ccagctgacc
      421 ggcagactta cccaccacct cccggcaaat acgattaaga tgcacggtag taatccccag
      481 ttctgctgcg aattgtgcaa tcgtatacct aagaccttct tcccgtatcc gctgttgaaa
      541 cttcctgaaa taacccaggg aatgattgtc agataaggta ttgcctgact gctggtcctg
      601 ccataaacga tacacggcca aaaacaattg ctgtaaacag atacgcagca tcaccttttt
      661 ttcgggcaga tcaccaaaca actctttatc tactgccttt atcaatgcta ctatatcttc
      721 agcggaataa ggaccattga agtcagcaaa acaccgtatt gttgtcagca tgggtgccag
      781 taatgctgac tcaggaaaca gtgtatccag catgacatcc gacaatgtca atatcctgcc
      841 gccggcgaca gtttcatacc ggaatccatg tagtgccata ggtgggatca ataacataca
      901 gggagtctgc aattcccgct gactatccgc ctcaaaaaaa gtcagcttcc cctcctcaaa
      961 gaaaaacaac tggtagatag acggatgtat atgaggttcg atattccagt caaacttcca
     1021 gctccttgta cccagcagtt cagaaaaaat atatcccgca tcgggtttag catcccggtc
     1081 gccatatagt ccttcatatt tgtctatacg cttcataaca gctggtattc atgttcgaaa
     1141 aatatccctc tcaatacaaa tatacctcct ttttaagcgc atctcttgtt aaccatgttc
     1201 gatttgtatc cgaaatatgc gcaaaagtct ccttacgtcc cttagcaaac acccaacttt
     1261 gcaacagtaa tctgacaata tgcaaaacaa gcaacatacc atcattatcc ttatcctggg
     1321 tctgctcatc gccctgagcc ccttttctat tgatatgtac ctcccggctt ttccggccat
     1381 tgcatccgcg ctgaagacgg acattgcaca tgtcggatat tcgcttacca gctattacgc
     1441 cggactttgt gcgggtcaac tcatatacgg tatcctgatt gatcgtttag gccgtaaaaa
     1501 gcccctatat gcgggtctgt tgatatacct gaccgcggcg tttgcgtgcg ccttttcatt
     1561 gaatattaat atgctggtag cggtacgtct ctttatggcg ctgggtggtt gtgtaggaat
     1621 ggtaaccgcc agggccatcg taagggacct cttccctcct aaagacacgg ccagggtatt
     1681 atcattactg gtactcgtca tgggtatcgc tcctatcatt gccccgacta tcgggagtat
     1741 tgtcaatacc attgccggct ggagatggtt attcggcgtc atggccctga tcgcactcgc
     1801 cttactgatt gcgacctata cattattacc ggaaacaaaa acacctgatc ctgatgtatc
     1861 tctccgcatc aaagacgtgc tgccggaata tatcgctgta ttgaaaaacc cggctttcct
     1921 cgtctacacc ctggctggtg gtatcagtta tgccggtctg tatgcatata tcgccggatc
     1981 gccctttgta tttatgaccc ggttcggctt cagtgacact gcttacagct gggcatttgc
     2041 tttcaatgcc tgtggattga tatccggcag tcagattaat cgcttattac tcaacagata
     2101 tgacagcata cacatctcct tttacgccgc tatcctgtta tttataacag gcttattgtt
     2161 gctgatcagc accgccctgg gtattgccgg cgcgccgatg acactctgct ttactttcct
     2221 gtttctcttt tgcctgggct tccttaatcc gaataccacc gcactggccc tacgtccttt
     2281 cacagcggca gcaggaagag cttccgccgt gttagggtcc atacagatga tcgcaggtgt
     2341 gattgcctcc tggaccgtta atttcttttt caatggcact gccaatgtta tggcggcagt
     2401 gatgttcggt tgtaccgccc tgaccttatt cctgttagta ttcttcacag gtcggcggcg
     2461 aacaaagcag gatttacagc cagcctgatc ccaacgggaa atacggcata ttttctgtag
     2521 tttaggatga gtctgatcat tcatttcatc catgagaaaa atactttacg cggttccggt
     2581 catttgcctc tttgcctgtt ctccccgact acagccgtcg cctcctgcaa ccttaacacc
     2641 gctgtccgat acagcatttg tagtggtact ggaagaagcg gacaggttca gcggcggaca
     2701 aaaagccggt gtcattcatt cgtcagataa taccattgcg cctgcctgta cctacgaaga
     2761 tatcatctcc cgtatgcaac aggcagcaag gacccgtggt gcgaacctta ttaagattac
     2821 cagctatagc acaccgcgcg ctggtaacaa ttgtgaacag atcacggcta acttatacaa
     2881 ggtgggccat cccaggtcat acgaacgtaa attcacctgg catcctgcac gtacactcag
     2941 ctgggaagac tataaaggca ctccctcaac gatccgcgaa gccaatgttg gcgcaagaac
     3001 ttcctgccgt ttcggaataa agatcgatac aggtagtaca cctggtaaag caagggtgat
     3061 cgtcaccagt gaatttatct gttaccagag cagtgtaaga cccaaccagc aaacaccctc
     3121 cctcctggca cacgaacaac tacattttga tctgtgtgaa gcatatgcaa gaagtctgcg
     3181 taagacactg gccgctacca acctgacgcc tgccaacgtc gccaggattt ccaaagatgc
     3241 cttcctgcaa acctatcagc tatacaggga acaacaggca ttatatgatg cagaaacaga
     3301 acatggtttg aatccagaag cacaggtacg ctggaagaaa aagatcacag atgcacttaa
     3361 cggattacag gcttatcagc aataacgcac aatgacgaat gtctgcaata aaatattttc
     3421 tttttatttt ttgcaacatt gttacatttg tatatcttta tgccatgtgt gaaacccaac
     3481 atacgtttat gcgaaaactg acagccttcc tcttgctgtc cgtgctgatg tatgtacagg
     3541 gattaaagac ctttcatcgc catgatgtca gtacagttaa ataccatgct gaggcatccg
     3601 atctcttctt caaaagcacc cacgaatgcg ctatctgtga ttaccatctt tgtaaagatg
     3661 cggtattgcc atcaataccg gtagtacaac agacgccatt ttattatatc gttacagacg
     3721 tatgcgatac gactgatcgt tcagtgaatc tatccgacac agtatccggc agaggccctc
     3781 ctgcccgctt tatttagttt cctacacact tttctgatac atcctttatc accgtatttt
     3841 cctatattat gttgcaagct attgcgctga ccaaagaatt tggccggcat acagcgctgc
     3901 acgcgcttga ccttaccgta caaaaaggtg agatcttctg tttgcttggt cctaatggtg
     3961 caggtaaaac cactaccgta aattgtttcc tgggttttat tgcacctacc agtggccgtg
     4021 cactggtcaa tggtattgac gtcgcgcaac aactgccgca ggcaagacaa cacattgctt
     4081 atatacccga aaccgtaatg ctgtatgcac acctgacagg acttgaaaac ctggtctttt
     4141 ttgactcact gacagggcat catcatagcc gggaacatta taccacccta ttgttaaaag
     4201 ccggattaca ggaaaacgcg atccacagaa gagtgaagac ctattccaaa ggaatgcgtc
     4261 agaaagtagg tatcgcgatc gctgctgcca agaatgctca ggtactgtta ctcgatgaac
     4321 ccacttccgg tctggaccct catgccagta atgaattctc tgatctgctc cgccgtttta
     4381 gtgaagaagg cagggctgtg ctgatggcaa cgcatgatct gtaccgagcc cgggaagtag
     4441 catcccggat aggcatcatg aaaaacggac gactcattgc tgatatggaa gctgatgccg
     4501 tagatcatta cacgcttgaa aatatctaca tggaacacat gcgtaccgtc tgatcaaatc
     4561 atccatattt cacaacatgt atctactact cacaaccaaa gagtggctgg ggggactgcg
     4621 tacctatgcc ttgccggccg tattactgtc gctgttagta ttactgggta ttgcctttgc
     4681 cggcacacac agtcgctcgg aacaaataag caggaacagg tcagctgcaa atgcgcattt
     4741 ccgccagcaa tgggaacaac ttaaaaccag tgatccgcac agtgcggcac actttggcac
     4801 atacctgttt aagccggtta tgctgctgag taatttcgac agcggactgg aaaccgtcac
     4861 cggtacttcc atgcgtattg aagcgcatgt acaacatacg atggcggcgc ccgtcttacg
     4921 acctgccgat atctacaccc gtttcggcag tctgactatt gccagcgtat tacaactgtt
     4981 ctttcccctg tttatcatct tcagctgcta caacagctat acccaggaga aaacaaacgg
     5041 tacactacgc ctcctgctga tccagggagc cacacaaagt gtcattctga agagtaaaac
     5101 caaatactat ctgatcgctg tcaatatcat gctgctggcc agcttattga tctatctgcc
     5161 tgcattactt ttttccggca ctaccactac tactacggat caaactaccc ttcttagcat
     5221 attatgtctc atcatcgcct acagcagcta ttgcagcatc tttgtaatga ttgcgatcgc
     5281 catatctgcc attgctaaaa atgcaagaca atcacttcta ctgctcaccg gctgctggtt
     5341 aatatggaat atactattac caagattggg cgctggtatt gccggtgaac tacatccgct
     5401 cccctctcaa taccagcaac aggaaaagat ggaaaaagcg attaaaatgg gcatagatgg
     5461 tcgttcctcc agagaagaaa ggatacaaca gcttacagat gccacactta aacaatatca
     5521 tgttaaaagc gctgaccagt tgcctgtcaa cctgcacgcc attctcctcc aatcctcaga
     5581 agactatgcc cagatggtct atgatatata caccgcaaaa acagatagta tcatcacact
     5641 tcagaacagg tacagcaatt acctggcgtt agttgatccc tatctggcaa tacgcaatct
     5701 gtcaatggcc ttgtgtggga cagactacct ccatcaacaa cagctggaca gagccgccag
     5761 acaataccgg aacgatttta tccgccggct gaataacgaa ctggcctatg gcggaagtaa
     5821 aacaaatgac agccactgga aagtaaatgc atccttttat agcagcattc ctcctttcca
     5881 ttacaagccc cctgcgctga tccaggtatt agcaagccag tggatgatga tcgccgctct
     5941 tttgttatgg ctggccatca gtatctgttt attacaaatc attgcacgac atgctggtat
     6001 tgaataataa aatcaacagc tggaagcaga tcatccgttt cgaactgcac accttacttc
     6061 gcacaggcac actcccggcg ctcctgctga tcatactgtc cgcaggaacg gcagcagtac
     6121 tgtttggtca tcatatcagg gtacatcagc tgaacacact tgatagcatc cggatagact
     6181 acagtataca gtatgataag ctgtataaag ggctttccgc tgatacttcc acaccggaag
     6241 gaaaagcggc ttatatatcc gcttcacatc ctgcggtaat agactatcgt ctgcacaaaa
     6301 ctgtcgcaca cccgccagct gccttttctg gtctgtctgt cggcatgagc gatatgacca
     6361 ggtattatgt tccggttaca gtgaaggaga cctatgtacc tgtggaagaa aagatcaata
     6421 atccgctgca cctgctgacc ggtaattttg atgtatcctt cctcattatc tacctcctgc
     6481 cgttggccct gatctgtacg agttacaatc ttctggcgca ggaaaaagaa cagggtacgc
     6541 tttccctgct gatcattcag aagggcggca ttgcagacct gttattttta cgcctgctga
     6601 tcagatatgc ggtcgtcctg tgttgtgtac tactgcttac attactcagc atcacattaa
     6661 ctcagacagc ttcatttgca gacaccctca gttggctgct gataagcgca gcctatctgg
     6721 cggtatggac tggtattatc tggctgctcc tctcctggaa tgcaggtacg gctgttagtc
     6781 tgattactat gctctgcgcc tggatgttcc tgcttgtcgt cctgccctcc ctgttcaact
     6841 tccgtctcaa tcatgcggat acggatgaaa acaccgctat cctggcctcc ctgcaacggg
     6901 agattgaatg ggatacatgg gatatgcccc agcaacaggt gctggatagt ttttatgccg
     6961 tatatcctgt ctaccgtaat agtcaggctt atgacaccag cgcttccagt acccgcagaa
     7021 tgatggccta ttatgacctc gtatcacggc gtatgcaaag gctcacggca caggcgacta
     7081 tcaaccgtat acagggaata caacagatca accattcata ccagtacaat ccggcagtat
     7141 atacacaggc tctcctgaac agtgtggcac ataccgacat tgctgactac gcctactttc
     7201 agcaacaaac cgcgctgttc cggcaacaat ggaaatcatt cctgtattac tatcatttca
     7261 atgataaaaa attcagcgcc gatgattacc gtatactccc agtctatcat ccatcctatc
     7321 gcccggatag ccggaaacta cagctacagg gtgtttgtca cctgttacta cttgccggcg
     7381 gactattact gacaggtact ttcctgctac gaaaaaacca tacaggacac cgtatttaaa
     7441 tcaatcattc aaattttcag gctgatgaaa aaatcactac ccataccttt tagtttatgt
     7501 ctcctggcaa taagtgcaca ggcgcaacaa aagaccgaca gtctgcgaaa gcagcacctg
     7561 aaggaaatag agatcatgga aaagaagaag aacatgcgca cagacagtat gtcgccggta
     7621 ctccggatgg aaggtcgtat gttggaaata ccacaaaata tcacaggtgt caccgccgat
     7681 cttatacgtg aacagggagg cctggaaatg aaagatatta tccgtaatgc cagtggcgtt
     7741 aaaataggct ataacagctc tgtttttgat gcttctgcca ctgtcatgat gcggggcttc
     7801 tatacagaca catatgtcaa tggtatgccc cagcgtagta caatgggcgc gctgacagac
     7861 gatgccgctt ttattgaacg ggttgacttt gtcaaaggac ccgccggttt tctgatctcc
     7921 tccggcgatc caggcggtag tgtcaacatc accaccaaga cgccccggca acagcgtgtc
     7981 cgtcagctgg aattgtcagg cggcagcttc ggcttcctgc gcggatcact ggatctgggt
     8041 agtgccgtaa aagagaaagg tttctcatat cgcctgaatg gcgcctatca gcagcaacag
     8101 agtttcctgg atttcctgaa aaccaggaaa tatgtggcgt cgccagttat acaatataat
     8161 ttcagtcgac ggacttccct gcttgctgaa tacaacttca ttcatatgct ctcagacggt
     8221 ggcagcagtg ttaccaaaat cggtaccgaa tccgaagtac tgaaagaccg catcggtaac
     8281 aactacgcag gcgatcctaa cctgccacag tcagggtcga agtcgcaaag catcagactc
     8341 gcattcgaac accgctttaa tgatcatctg cgactgacca tacaatcaaa atacacggtc
     8401 aactctactg ccgtatggta cctcatatca gataactact cgctgattaa cttcgacagt
     8461 accaacatta cccgccgcct gccggtaaac aatagcatca ccggacgtgt ggcagcggta
     8521 caagcttatc tcagcggtaa cctcaaaacg ggtcagcata ttacgcacaa cttcgttgcc
     8581 ggactcgatt acaactacag caaagacaac tatgtgaatg cttatggtca atatgcgttt
     8641 acgtttgaca gaactcatcc gcaatatggc ctccatccgg atagtgtaaa aatgctgggc
     8701 aagcctgcat tgattgtcag agaaaataac tggacttccg cattcgccta taatacaacc
     8761 cgcattcata ccaactggtt gttcaattac ggcggacgtc tcacaatcaa tacgcccgtc
     8821 accacgaatc caaggcagcc gcaaaaagat gaaacggcct tttcccccag gctgggtatt
     8881 acacgactgc tgaacaacaa tatggctgtc tacgctttat atgaccagtc atttattccg
     8941 cagtcaggtg taaatgctaa cggacaacga ttcgatcctc aacgtggcaa cagcttagaa
     9001 gccggcgcta aaaaggaatg gtttcagcat aaactcatga ccagcatcgc cggttacagg
     9061 atcctcaaga ataacctgct ggtatctgac ctggaacatc ctggtttcag aagacaaatc
     9121 gggcaggtaa cgagtaccgg cgcagaactt gatatcaccg gccgtattgc tgaccggctg
     9181 tcgatatcag ccaattattc ctatacacac gctatcgtca gcaaagacag caggaaagag
     9241 aatgaaggaa ataaactggc ttttacaccc gaacaggtca tcaacagctg gatacaatat
     9301 ggcatcccat taaaagcagg atcccgcctg agcctgagcc tgggccacaa tacagtgacc
     9361 aaaacagcca cttatacacc cggtttcgat ctcaaaggtt atacaaagtt tgatggcggt
     9421 atcgcatata cacatggcaa atggtatctg cgtgtcgtag ccgacaacct gaccaacaaa
     9481 cgttatttct ccagcggcga tatgctggta ggatccgtct atgaaggggt aaagacctac
     9541 tactacatag aaggcgcccc catatcgttc aaagcattcg caggtatcag actataacat
     9601 tattgcgcaa taggggatat gccgaaaccc cataacagta ggcatcaata cttaaatact
     9661 attttatgaa agacaatcag gtaacccaga tcaaactgag catcgatgac ctcaaaatcg
     9721 acagttttgt aaccagtatc gacagcgaaa tgaatatgcg tctggcgggc ggtctcgcag
     9781 gccaaagcca tccaacgcat acagtagcta cagatgatga aggacatctg tgcacgacca
     9841 ttatctgtgc ataattttgc aggatatgaa aaagccgtcc accaaaggtg agacggcttt
     9901 ttgtatctta gttatataat atgtgcaaaa gtatacggtg aacgatatct ataacaaatg
     9961 atgcacgtcg ctaagtcctt accaacataa acaaccgctt ctatttttgg gtaatcatac
    10021 attgccgtaa gaacacccgc acctgtgaca gtaccgcttc ctgcaaagca gccatcccaa
    10081 catctacctg aggataaata atatcagtga tcaattgcag taatggtaac tgcccctcga
    10141 atgcctttaa taacattgct gtaaactgat taacaggaaa ggtacttact ccctgcacat
    10201 gtgcaatatg tacatagtaa tatcctgtac tttcttgttg attggtgact gcctccccat
    10261 gccaggcgtg atcagtagca cataccatta actccggaac cggcacaaaa acagtctgca
    10321 acaacaccct atcattctcc tgcaacaaat aactattccg cttttccagt aaccgattgc
    10381 gttgctggta acacagccat ccgctatgcg atcgccatac atctgccaga cttttctcat
    10441 acctgaaaca atcctggtcc cccatctcct tctctaacag ctgctccagt tcatgcatgt
    10501 cattagcgat cagcgcggca ggatattgct gcagggactt ctcataataa cggctaaaca
    10561 gcgcccgctt tacctcccct ttctcataca aaggcacatc tttcctgttc ctgctgatca
    10621 atggcgccat caccgtattt tctttgtatg gcagtaatac actgaccaac agatatccta
    10681 cacccgccag tcctgaaaat aatcccgggt catcttgtgc gtctttaatg taactgttat
    10741 aagtgccatg tgcctcaaaa taacgtatgg cggccattgc gatccgctgt gctgtttgtc
    10801 gtaaaaccgg cctatcgaat acagcccctg cttccattaa gaacatccct atcccgccgt
    10861 aaccactaca caaggtaaaa tctccccgca tcagggtatc cgcatcctgc agacaacgtg
    10921 tcaatgccca ttcgctttca gcagcaaaat gggcttctcc gcttattccc caggcataca
    10981 tccgacttaa tccgataccg gcggccccat gtgcccatgc attcacatca ctgatatacc
    11041 ggcgaaaatc agcaatctgc cagcccataa tatccgtttc ctgtaaatgg gtacttgtga
    11101 gccgcaggtc cagccaattt ttaaataccg gatcataata tttcatctca tacgcccagg
    11161 actgcatcgc caggtaacgt aagccttcgt cttcaaaata aactgctacc tgtaataaag
    11221 catgggctat gcctgctgcg ccatgagaca gtcctgtcag acaatcatac gaccgcttca
    11281 gatgccccca gcgtaatccc tgcgcagcaa tccgtgcatg tgccactaat ttgtctgcca
    11341 gttgccggat caacacacgc aatgagtcat cctttgtata ggcatgtagt tgcgtcaaca
    11401 ccagtaagtt acctgcatgt ccactgatga aatcatcctg tactactttc tgcaagatgc
    11461 cttcctggta atgcgctacc agtgcaagcc ctcgttccag gtatcgctga tctccggtgg
    11521 cctcatacaa ctgtatacac aaatacacca gactggtcgc gccggtatat aaggtaaaaa
    11581 acgcctgctc agaaatagcg ggatgatata gtaatacatc tgcggcggcg gtacacacag
    11641 gcagataccc cggatcatat tcagccagac gcaggtaaaa cacaatgata ccggcctttc
    11701 cattgaaaag gtctacaggt gcgccattat gcaggtcagc agcaatcgtg tccggctgga
    11761 tagcgggtaa aagcttttcg gccaggtcca gcaaagcagc cgctatcact tgttcatctt
    11821 tcagatttac cgccggcata gacattctcc aaacatttta aagtaaagaa cataatatag
    11881 gcttcatcca gattcgatac ccccagccgg ttatgtccca tgtgcataaa actacctgtg
    11941 atatctctca tgctatgatc gtcaaatccc agacggctgt attcctggaa gatccgccgg
    12001 ttagactgca taaatgcctg tagacgcggt gttgcttttc ctgtatgtaa cgcttcccat
    12061 agcgtagcag tagcaggtag taacagtgga gcatagtggc tgaaacgatg atcaagctgt
    12121 gttgtgtaat attgtttctg ttcggcagca aacttactgc gatcatacaa acggggcaac
    12181 cattgatcaa taaactgccg gcaggttgct atcatctcat gagcaggaac atccagcgca
    12241 caggctatgg ccatattcat tttaagcgct tccagcaagg caccggaagc atcccattcc
    12301 cgtttgttat tgagtacatc caacacataa gcggaggaac acataaactg ttcttctgcc
    12361 caggcaatac tatcctcatc accatagcgt gctatttccg gttcataggc gataaactgt
    12421 atggttagtc cttctatcac acgccctgcc gctatcaact gtgattgtat aagtgctata
    12481 tctgcactcc ctggcagcaa tcgtaacctg atatgcggtc ctccttcgcc ataacggata
    12541 aagaaacccc tgtaaggggt atcacgtaaa aaaggcagca ccatctccaa taacaggaat
    12601 ctcagatctc cccgataaaa aagatgtgcc gataaccaat tccgctgcat gtattaccta
    12661 ttataccagt gtaataaata ttctttcaca acaccgccgt cagccgcaac atgtgttgca
    12721 gcaggcaaca tttcttccag gtaacaccac tctcctgccc tggacaagac ctttctgaaa
    12781 agcgtggcca gcagcggatg actgaaatcc atatactgtg gcttataatc gtcccgttgt
    12841 aactggctct tttgcccatt cacaacaggt atataggctg atcgcaggaa cagaaaacac
    12901 tgctcaggta tatcgttttc tattctccat gtattcagcc gcttaaaata gtccgcagca
    12961 gattcctcgt ttccacacaa gggtataaaa gccgtctgaa ggagccagcc tttccgccgt
    13021 agtaccacct gttcgccgaa agtaatacgt ggttttacct gtatacgctc gttaggtgga
    13081 tagatcgtgg catgtttacg gtcaagcgca gtaatcattg cccgtagagg cacccgttgc
    13141 accgtattga agtgggctaa taacctgtaa aagtgcgaac ggttataaaa ggactccaga
    13201 ctaagatcaa aggcgtaaac cggcttattt tgccctttat gaaacaaaga cagtgttctg
    13261 gtagccggct catgtttcac cacaagatcc tttaaggaga cccgggcctc tgctgcatag
    13321 atattatttc ctcctggcat agccacttca taaggcaata aaggcggatg gatatttgca
    13381 ttgaaggccg atccgtcatt cagttccagc aagagatgat ccgtatacaa gtttttattc
    13441 caggtacgaa agtcagctgt cactacagga ggcaataaat gcaggaaacg ccctgccact
    13501 tttcccatac ctggcaacag ggcattgata acgcctttta tatgacttcc ctcctggtaa
    13561 aactgtacaa aagcgcctgc gctgttattg tcagggatca cttctatggc cggggtaata
    13621 tgtactgtat cctgctctaa taccagttga agcgtatccg gtaggtggat ctcctttatg
    13681 tctttttttg cctgctggtc tgttgcctgc tttttctcct gcaggtaata gtcatgataa
    13741 aaccgtgtga ccggcacttc agcaccttcg tcataatgct gcacaaagaa tcgctgcata
    13801 tgcgcccgtt cttccgctaa agcatccagt ggcgccagca gcgtacataa ctgattaatt
    13861 tcccttgtaa atacagaaag agcagtcgct ggtaatatgt cagccctatc agtaaaagcg
    13921 tcttcataga aaatgtcctg cggcaaaaac cggcgtgcct gaaaacggaa caattcaaat
    13981 acaccctctt tcagcggcat ctcatctggc aaacccgcct cttcctgtaa cacacgaaac
    14041 acatcctcca ggctaccagc tgtttccagc agtaagcgat gccgcctgtc tgccgtagca
    14101 atagcataag cggttttggt ttgctgtagt tccgataaca tcttcaataa caacgctacg
    14161 gcctgctgat ccgcatacgg tgtaaggaat tgcagtaact gtccatccca atccggatca
    14221 atacccgcac accctattcc tggttccagc aaaccattaa atacgagttg cagtaagaat
    14281 gatttaatcg cacttctatc tgtatctgct atctgactac acagctgatc ggtcaatccg
    14341 ccaagtgtca ctatcgcttc tctgtcctgt aactgatgat ataaccataa aggcagattg
    14401 cgggccggca aacgttgaaa ggcctctaca ttgaagtaat tgacaagaaa ctgtaattcc
    14461 tcctgtatga tggtggcggt cacgtttaac cgtaatgtga tgatttcatt caataccgga
    14521 tgatatataa tgagcagacg tatatagctg aacaacccgt tatgcaaacg gatgtcgcta
    14581 tgtatctccg gtgttgcggc tgctgcatcc ggcgtaccca tcttccccaa ccctgtatag
    14641 gtaaaggtgc tgaacgggga tgtcttggca gccatacgac ttatatagcg gataaggcta
    14701 tgttcattct tcagcgtacg acttttaaat tgcctgctat cagcaagagc aaaactatcc
    14761 agctgttcat acagtacagg actggataat aaaatacctt tccgcagcgc ttcgtcctgc
    14821 acgtaaccct gtaattcccg tctggcagct gtatgctttt cctcaaaata atcccgccat
    14881 tgcacttctt ccttttctct gtcaacaagc tgttgcagat atgctttcat tgtttcggga
    14941 acaaatgcag gtaatttcac aggtcgttta tcattaaaaa tatcccgctt caattgcagt
    15001 agctgacgtc gttctttatc atcagtcgac tgactgatag cagtatataa cagatcgcag
    15061 acggcttctt tctgcgctgc caattgtttt gcagactgcg ctgtttcctg cagatagtct
    15121 gctatgtctt tcactttcgc tgtatgcagt acgctaagcg gcataccggc atagcgcaca
    15181 aggatatgcg gaaaaatgct gagtgccata ggaaagtatt tttcaggtgt aacaatgtct
    15241 ttttacctgc cgagttccag ctggttttta atcaggcgat aataagcgcc ggctgctatg
    15301 gtcaacgttt catgtgtacc ggcttcaacg atcatccctt tatccattac caggatctga
    15361 tctgcatgtt taaccgtact caggcgatgt gctaccacca ccactgtttt tcccacgaag
    15421 tattcatgta gattattgat gatcgcccgt tcattactgg catccagtga atttgtggct
    15481 tcatccagga atatataggc gggatcgcga tagatcagtc ttgcaatcag tagccgttgt
    15541 gtctgtcctt cactcaaccc ataaccatcc tttcctatca tggtatcata accgaaaggc
    15601 attgctgcaa agaaatcatg aatattcgcc atcctgcagg ctttcatcat acgctccaca
    15661 tctctgtctg cttcaccgcc atatacatta ttggcaatgg tatcccggaa cacatagcca
    15721 tcctgcatca cggctccaca ctggcttctc cagtcttgcg cagtaatagc tgtgaatgac
    15781 tgatctcccg caaagatggt tccctgtgtc ggatcgtaga attgcagcaa tagtttcagc
    15841 aatgttgtct taccactgcc gctcatgccc acaatcgccg tcatcttacc agcgggtata
    15901 cttaggttga cattattcag tacaagcgga gaatgtttat tgccatactg gaagtataca
    15961 ccggagagat gcagatcacg ccctcccata tcctctgtga tcgtattttc ctgcggaggg
    16021 tcttcatcct gttcatgatg aacctctgca atacgttgca gactaaactt cgtattttgc
    16081 atggccctta tgaattcggc cagctgggct accggcgcgt tgagttgtcc gcagatgtaa
    16141 gtgatagcca gcatttctcc cagtgtcagc tgtcctttga tcaccagtat tgctgtaaaa
    16201 caggtgatga tcacattgcg ggtctcattg ataaacaatg cgatcccctg tataaactga
    16261 tccagtttca ggctttccag tttgacggta aaagactgtt gttgcaggcg tgtccattga
    16321 tttattttaa gccgttcgct acctgtgagt ttgatctcct ggaaagcgga aaagatttcc
    16381 aggagcgtgt cctggttcgc cgccagtacg cggaaacgct tctggtccag acgtccgcgt
    16441 ttttctccga aagcccctgt ccacaaaaca cctacagcag cgccaatggc aaacaggata
    16501 aaaataagcc agttataata cagcaatgta cctcccatga ccagcaggat catgaccgac
    16561 atcacaaagg aaacagcgga agtggtcaga aaatcttcta cccgttgatt gtctgtgacg
    16621 cgttgcatat tatcacctga ttgcctgtta tcaaaaaagg agaaaggtaa gcgcatcagt
    16681 ttcaggagga atgcttccag catcatgata ctcatctgtg cccctagtgt cagcagcaaa
    16741 cgggcacgga agaaatcagt aacctgtttg ccgaggaata atgacagctg ccccgcacag
    16801 atcagtaaca ggatgggaat atcctgttta ttgatgcccc ggtctacaat cgcttctgtc
    16861 agtaatggca ctataaaaga caagacggcg gctatcagca gactcacacc tacaggaatt
    16921 aactttcgcc ggtgactgct gatatatggc cagagggtac gcagatcagt aacaggtgct
    16981 tttacttcgg tggctgcatg aaatgccgct gtgggttcca ggaatagtgc ccttccgaat
    17041 cccggtttat ccgccagttg ccaggcctcc atgaattccg gaatggtata acggatacgg
    17101 cgccctaatg caggatctgc cacatatact ttatgttccg tcagccggta caatacaaca
    17161 aaatgctgcc ggtcccaatg cagtatacag ggcaatgggg cttttgcggc caacacggta
    17221 aaaggcagtt cagccgaaag ggtgttaaaa cccagttgct ctcctgcggt tatcagatcg
    17281 gcaaaagtga caccttgacg ggatatttta cattgacgac gtaaatattg taaaggatag
    17341 gtcttcccat gccaggcagc aatcatctgc agacaggtag ggccgcaatc cattgcgtct
    17401 gcctgcctga aaaaagggaa ggatttcctg gggaatagga attgaaacat tgttgcaatc
    17461 tatgtaaaaa taaaatatga aacaatgttt cataaaatat tatccggaat aaatgcaaac
    17521 catcttttaa aaacaaaaaa ggcatccgca tatgcggacg cccgaaacct aaccctacaa
    17581 ctgttaaaaa ccttaccagt actttgtacc cagtactctc gccagttcca gtcttgccag
    17641 acaaagctga taagtgtact gcaatgttga ccgctctgcg cgctgtacat tggtactggc
    17701 attagttagt tccaggttgg tacctgttcc gttcctgtat ctgctctgcg ccagtttctg
    17761 tgcttctttt gcctcctcta cctgttccat tgcgttgacc aacctggact gattactttc
    17821 aatatctgta tatgcctgtt taatatcatt ctgtacggta ttgttcaacg tctgcatacc
    17881 caggttcgct tccttcagct gactctgtgc gaggctacgt tgcctcctgg ctctcgcacc
    17941 ctgataaata ggcacgctca atgtcacacc tcctgcatag ttatacctga actgattgag
    18001 atcaggcata tatccattgg caaaaccggt actcgcactc aaagacagcg agggcaatcc
    18061 ggctttctta ctgatatcca atcctgcttc cgactgactg atcctgtctt tcagcagtgt
    18121 atactccgga ttatgctgtt gtgcgatgtt caatgcctcc tgtttatttt cgtttgcctg
    18181 catgaaatca aaatccttcc cattggccgc agtactacct gttgaatact gcaggaggtt
    18241 gtattgcttc aacagcgagt tttccagatc aatgcgggta ttgttttcct ggtcgatagt
    18301 cgactgaatg gataatacgt catagcgcag tgcatcaccg tgtttcagct ttatctctgt
    18361 atcctcctta ttggctttca gaaaagccag cacactatcc tgtatagcaa ttgctttttg
    18421 cagatagacg atctgatagt aaatcaccgc tacctggtaa gccatctgcg ccctgttata
    18481 ttcgatgtta tccttggcat attgcaccgc acgtttagca ctctccacat tcgcctttac
    18541 taccccaaag tcccataaga cataactggc attcagaccg gtgttataat tactattcgg
    18601 cataatctta aacgtggata gctgtccgtt gataggtatc gtcatctctg ataccggatg
    18661 cgaataacga taccctgcac tacatgtcag attcggtaat ccatttgcct ttgccagcgt
    18721 aactctttcc tcctctgttt tcacggattg ttccagttcg ctgaaacgcg ggaaataagt
    18781 aaatgattta ttgattaatt ccttcagatc actgctgact tcctgtgcat agctttgtag
    18841 ccccgcaagc gagagaaggg atatgataat gacttttctc atgatgtaaa ttttttaaat
    18901 aagatcaatg cgcctctgcg gcaactctcg cgcgtgtttc ggcatccatc ttttctattt
    18961 ttaacagtaa catgaatggg atcgtgcaga cgaaaaacac acttaccaac aggaagccat
    19021 cgagataagc aagcatctgt gcctgtctgg taatggcata atccaggtta gaccaggcgc
    19081 catgggcatt agccgcgatg gggttgacac ctttactgat caggccctgg gcgacacctg
    19141 ctaccctttc attcatcaac ggattattcc cttgcagatt ggataccagg tcagaacggt
    19201 gtaccgcaaa acgctgcgta gaatacgtat tcatgatcgc gataccgaat gcaccaccaa
    19261 tctgtcggaa catgttattg agtgatatac cataaggcat gtcctgtggt ttgagtccga
    19321 cgaccgcctg acttaacaac ggtaccgtca gacaggcagt acctacaccg cggaagatct
    19381 gtgtatacat aaaccaccat ttatctgcgt caggtgttgc ctgtgcgctg gtatatccat
    19441 ggaggataaa caagccgaaa ccagtcacga caaagaacat gggcgatacg cctttaccca
    19501 gtgaagcccc gataaaaggc attaccatga tcgtgactaa tgccccgggt atcatagata
    19561 atcctgattc tgtaggcgta taccccatga cgcgctgcac catcagcgga aacagatata
    19621 cagagccaaa caatccgaag ccacatacaa aggtgagcac attactcccg ataaggttcc
    19681 tgcttttcag aaccctcaga ttgatgatag gcgtctttgt ctttagttcc caccagataa
    19741 atgccgccag tccggctacc gctattgcgg tcataatacg gatcgtgctg tcttcaaacc
    19801 agtcgtctga ttgccctttc tccaggatat attgcaaggc gccaattccc gcagataagg
    19861 agagcacgcc gatgtaatca ataggaatgg atttacggtc gatgttgtat tcattttctt
    19921 ttttatcgat gaacttccag gtcagcaaac aagcaacaat accaaacgga atattaatat
    19981 cgaatatcag cggccatgca tagttatcga cgatgtagcc gccgagtatc ggccctattg
    20041 ttggtcctat cacgataccc attccgaaca tacctgaggc ttttcccttt tcagagggat
    20101 cgaaggcatc gaataatatc ccctgtgata cagaaagcag ggcaccaccg ccaacacctt
    20161 gtataaaccg ccagaagacc agcatccaca aggaggagga agaaccacac atgtaggaag
    20221 ccagcgtaaa tatgataata gaagtaaggt aatagttctt tctcccgaag tagcggctga
    20281 ggaagcctgt catcggaata acaatcacgt ttgcaatcgc gtaggctgtt actacccagg
    20341 aagtatcctc cagtgtagcg ccaagattac cgctgatgtt attgagtgcg acgttaacaa
    20401 tagaggtatc tatgagctcc atgatagccg ctgaaattgt ggtaatgact atgattaccc
    20461 gcgtaaattt atttaccgcc atatactatg ctgtttaggt cttaatcaac ctgtacatct
    20521 acagttacgc taagacctgc tttcagtata cttttcagtt cttctgcgcg gtcaatttca
    20581 attttaacag gcacacgctg tgtcaccttt acaaagttac ccgtagcatt atccggtggc
    20641 aggagcgaaa atttagcgcc ggtggcatca ctgaaagcga cgattttacc ggagatctcc
    20701 ttgtcaggat aaccgtctac ttccactttc acaacctgtc ctattttcat cttctccaac
    20761 tgggtttcct tgaagttggc aacgatccag tagcgttcat tgttcacgac gctgaacagc
    20821 tgttgacccg cctgtaccag ttgtcctttc tgcagattgg ttttcccgat tctaccggct
    20881 accggcgcta tcacctgtgt ataagataat ttcagcttag ctgattccag tgcagcttct
    20941 ttcagggcta cattcgcctt tgctttttcg atctgtgcat tggcggtacc atgctgtgtg
    21001 actacctggc tcacgcgttt cctggaagat tccaactgac tcaatgccac tttgtaggca
    21061 gactgactat tatccagctg gtgctgtgtg atagaaccat cgttaaacag ggcctgatct
    21121 ctggcgaggt cgcgggttgc tttttccagg ttaacctgtt ctacactgac acctgcatcc
    21181 gctacatttt tatccgagcc gatattggtg atctgtgctt ctgcaaatat cagatctgct
    21241 tttgcggcgg agagatctgc ttctgcctgt tgtacggcaa ttttgtattc cttatcatca
    21301 atggtcagca ataactgacc tccttttaca gactgataat cctgtaatgc aaatgtatcg
    21361 atgtagccgc cgaccctgct caccacagga atcgcattgc tctcaatctg tgcattatca
    21421 gtgctttcat gtgtataggc gtgcattatc ttctttcctc cgaaataaag aattgctatt
    21481 ccggctacgc ccaatacgat aaactttacc gggcctttag atggctgcgt tttttcctgt
    21541 gtcattcctg tgctaggtta tttgtgcagt acaaaagtaa acattgttga ctatatagta
    21601 aacactattt actatttttt tcttttgatt ttttttatta aggggtattc tggcaagggt
    21661 ttgcccgtct ttatacgggg aaaagattat ttttgcgcat ggccatgaaa gaaaaaaata
    21721 aatcaacgga taaggacgat aacctgtttg ctacattata tatactaaag cgggcaatgg
    21781 acgactgggg tagccgcaac attgctaact ggggttatga aaatttcaat attacttata
    21841 tgccgttctt tatgaatatc ggcaatgagg gtgtttccaa taatgagatc gcagaaaaga
    21901 tgcgggtgac caaacaggct gccagcagga ttgtacgtga gctggaagcg tctggtctgg
    21961 tgaggggtga gaagagtgat agtgacggtc gttcggtaaa actatacctg acggaagaag
    22021 ggcataaatt ccaggagatc gcgaagaatg aagccaaaat tttgagaaag gaatatgtga
    22081 aagtcatcgg tcgcgagcgg tatgaaacag ccgtggatgt attgaaagaa ctgattgcgt
    22141 ttcatgaaaa tttattgaaa tagtcaaagc ggttgcccac cggtaaccgc tgctttgtat
    22201 ttatatacac tattcctgtc atcattcctt atcccctcag tatcaaccac caatatgcgc
    22261 aaatcccccc ttatattcaa catcctcagt tagtcctctc tatcaacgat ttataacaca
    22321 tcccccgttg atcacctttc atttgtccca ttacaccggc attatcccgt catcaagccg
    22381 ttaccgctac gctcatgaac gaagagataa cggcttaata gccctgtaat aagggcattt
    22441 atcgtataaa cagtaaaaca cgtacacacg tttttgcgtc ctgtgcacac gtttttgcgt
    22501 cctgtgcaca cgattttgcg tcctatgcac attgtccgaa atcgtgtcag acggttcggt
    22561 aactttgtaa ttcaccaaaa cgatatcact atggcacacg taaaagacaa catcttattg
    22621 aaaaatgtgt ccggtaccat cggcagacaa atgaatattt tcaaccgtta tggcgagacg
    22681 tatctgagga cagcaaagaa gaaaaaacag ctgcattttt ccgccataca gctggaatca
    22741 cagcataatt ttgcggatgc agtagtgtat tcaaagcagg taataaaaga tccggagatg
    22801 aatttgtatt acctgtcact tgcgaggaaa ggacagagtg cgtataatgt ggcgatgaag
    22861 gatgcgttga gcgcaccggt gatcagggat atagatgccg atacctatac aggcgaaagc
    22921 gggcaggtga tcagcatata tgcggtagat cacttcaggg tttatcaggt acatgtagcg
    22981 atcattaacg ctgcaggaga cactattgaa aaaggacttg ccgtccagca atggaaaccg
    23041 atgtattggg attacacgac gacgatgcct acggaaatag cgcaggtaga aaagatacag
    23101 gtaatagcag tggacatgcc gggaaatcag acaaaagcgg tactcacatt tacagatgga
    23161 taaataaata agccggaaca ggaatgtccc ggctgacctt aaacctacaa ctgttgccga
    23221 tgatcagcaa ctaaactatt ttaatatcgt tttatcgtgt tgaatacgct gggccgaaga
    23281 tcttacaatc cattttaaat ctcaactcag acgccctgaa acggacaaat tacccgctga
    23341 aacgccctgg ctggaaaaga cttaggggcg catgaatacg cccctttttc tcatattctg
    23401 ttacgaatat gtatgtgtac cttatagatg aagtatgtgt gtatacgatc acgcatatac
    23461 aaacacaaat gtccgtatat gcaaggctgc cagccaacaa aactgtagtg aaacagccat
    23521 attgcctgtt gaagtgtgtt atagaggaat taatgaatat caacgctgtg tcagccattc
    23581 caggaattgc cccatcttct cacgactgat ggtaacagat tccggtacag gcactgacaa
    23641 agaaagcgtc agtttgcggg aaagggcact ggaagcatcc agtactgcct tacgatgcac
    23701 aagatactgc ctgttagcgc gaaagaaaag cggttctgta aatttaccta gttcgtccat
    23761 cgttttattg acgacatagg tctttttatc aaaggtagtc aggttaacca ctccgttttt
    23821 caaatagaaa aaagcgatat cactgatcgc caccggcatg atcctgtctt tctggtatac
    23881 aagtacagcg cctatttcgg ttgttttctt tgtagtaaac agctgttcca gtgctttata
    23941 gggaacggca ttctctgcaa tccgccccct gaaagccagg tatttattaa ttgcggcgga
    24001 tactgactcg ttggtaaaag gcttcaggat atagtcaaat ccgttagctt taaatgcatg
    24061 taaagcgtat tcatcatagg ccgtacaaaa gatcacagga acgtctattt ccacggcgga
    24121 gaagatctca aagctcagac catctcccag ctgtatatca gcaaagatca ggtccgcgct
    24181 gcgatctgaa ctaaaataac tgatactgtc cttcactgta cccagcacct ttaagatgcc
    24241 gatctgcgga aacagttgct gaatggtctg taccaggtct cgcgcggtta ttttctcatc
    24301 ctctatgatc actaccttca ttactcaaaa ctttaatgct gactgaaaag gtatgcaaat
    24361 cctgtgagat aatcacctca tctcctgaca atatccggta cctttctacc aggttaatca
    24421 gccctttacc actctgggaa tcaatatgtt ttctgacctg cagattattc tccgtaatga
    24481 tccatccctc ctggtagtac atggtaatgt gcaagggaga tgcctctgtt gcttcattgt
    24541 gcttgatagc attctctatc agcgattgaa gagaaaatgc aggtacaaaa ccggttgaca
    24601 ataccttttc ctgaacatct atggtacaat gcagcgcatc ttcaaaacgg atcttctgca
    24661 tttcaagata atcgttgcag agctttatct cgtcagataa acgggtagca cgggattgcg
    24721 gttctgccag tgaggcccgc agaaaattta ccaggtgcga aagataagcc tctcctgcct
    24781 gaatatccgt cttatacagg cttttcagca tactcagagc gttgaaaagg aaatggggat
    24841 gtatctgctg tttcaatagc agattggccg attcaagatt ggcggctttc agacgggaat
    24901 tttccagttc aatattttct ttttcgaaac gtagaatcac gagattatgt gtaacaatta
    24961 ccagcaaact attccagaaa ccttgcaaca aaactgccgg cagccgttgc aggaaagtaa
    25021 aatgttcttt tgccgcatca aagtaagcct ccatgggaat ggtcagggaa aataaacaac
    25081 aggtaagcag atatcccgtc acatacctgg tgatgcgctc ctgcttcttg gtctggaaag
    25141 gaaaatactt tctcagcatc accaatatcc agacattaga aaaccccgcc atcagcgaac
    25201 gtatacctg
//
