BGC0001399 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001399 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	24,001	fellutamide B	NRPS:Type I	100%

BGC0001399 - Region 1 - NRPS

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Location: 1 - 24,001 nt. (total: 24,001 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,002
Label		BGC0001399

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399	1.00	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001261	0.29	NRP	AM-toxin	Alternaria alternata
BGC0002135	0.27	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002518	0.27	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001166	0.26	NRP	HC-toxin	Alternaria jesenskae
BGC0000313	0.26	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.26	NRP	enniatin	Fusarium equiseti
BGC0001833	0.26	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825	0.25	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000396	0.25	NRP	nodularin	Nostoc sp. 73.1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399	1.00	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001261	0.63	NRP	AM-toxin	Alternaria alternata
BGC0002135	0.61	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002518	0.61	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001166	0.60	NRP	HC-toxin	Alternaria jesenskae
BGC0000313	0.60	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.60	NRP	enniatin	Fusarium equiseti
BGC0001833	0.59	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825	0.59	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000396	0.59	NRP	nodularin	Nostoc sp. 73.1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 24001:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Asn - Gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_03496

Search NORINE for peptide: strict or relaxed

AMP-binding (591..997): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSNVGSIIK
Nearest Stachelhaus code(s):: Asn DVSNVGSIIK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1700..2097): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQNIAVINK
Nearest Stachelhaus code(s):: Gln DAQNIAVINK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ANIA_03495

Search NORINE for peptide: strict or relaxed

AMP-binding (478..871): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLYSAVAVVK
Nearest Stachelhaus code(s):: Leu DLYSAVAVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ANIA_03490

AMP-binding (45..464): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GLAYVGGVIK
Nearest Stachelhaus code(s):: nohBza GLGLVGAIIK (32% 8Å match); cycHexAla DLLSVGGVFK (29% 8Å match)
Stachelhaus code match:: 60% (weak)