BGC0001400 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001400 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	15,466	citreoviridin	PKS	100%

BGC0001400 - Region 1 - T1PKS

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Location: 1 - 15,466 nt. (total: 15,466 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,467
Label		BGC0001400

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001400	1.00	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001254	0.31	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002192	0.29	Polyketide	FR901512	fungal sp. No.14919
BGC0001268	0.22	NRP, Polyketide	fusarin C	Fusarium fujikuroi
BGC0000064	0.22	NRP, Polyketide	fusarin	Fusarium verticillioides
BGC0001244	0.21	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001275	0.20	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001998	0.20	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0002139	0.19	Polyketide	burnettiene A, preburnettiene B, preburnettiene A	Aspergillus burnettii FRR 5400
BGC0002745	0.18	Polyketide	verrucosidin	Penicillium polonicum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001400	1.00	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001254	0.64	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002192	0.63	Polyketide	FR901512	fungal sp. No.14919
BGC0001268	0.55	NRP, Polyketide	fusarin C	Fusarium fujikuroi
BGC0000064	0.55	NRP, Polyketide	fusarin	Fusarium verticillioides
BGC0001244	0.53	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001275	0.53	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001998	0.52	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0002139	0.51	Polyketide	burnettiene A, preburnettiene B, preburnettiene A	Aspergillus burnettii FRR 5400
BGC0002745	0.50	Polyketide	verrucosidin	Penicillium polonicum

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15466:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_09617

PKS_AT (474..789): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 77.5
Methoxymalonyl-CoA: 63.9
Ethylmalonyl-CoA: 57.7
Malonyl-CoA: 55.7
Isobutyryl-CoA: 49.9
Propionyl-CoA: 29.8
trans-1,2-CPDA: 28.2
Benzoyl-CoA: 26.9
fatty_acid: 16.7
2-Methylbutyryl-CoA: 15.8
CHC-CoA: 5.2
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0