Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001402.1:
Cluster 1NRP138425

BGC0001402, cyclochlorotine / Hydroxy-cyclochlorotine / Cyclotine / cyclochlorotine B / Deoxy-Cyclochlorotine biosynthetic gene cluster from Talaromyces islandicus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: cyclochlorotine
PubChem ID: 57134655
SMILES string: Copy to clipboard
Molecular formula: C24H31Cl2N5O7
Average molecular mass: 572.44 Da

Class-specific details

Biosynthetic class(es):
NRP

Gene cluster description

cyclochlorotine / Hydroxy-cyclochlorotine / Cyclotine / cyclochlorotine B / Deoxy-Cyclochlorotine (BGC0001402). Gene Cluster 1. Biosynthetic class = NRP. GenBank CVMT01000002, positions 2179859-2218283. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Literature references

1. Schafhauser T et al. (2016) The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum'). Environ Microbiol 18(11):3728-3741. doi: 10.1111/1462-2920.13294. Epub