BGC0001436: cornexistin biosynthetic gene cluster from Paecilomyces divaricatus
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Location: 1 - 58,291 nt. (total: 58,291 nt).
This entry is originally from NCBI GenBank MF197864.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001436
Short description cornexistin biosynthetic gene cluster from Paecilomyces divaricatus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: MF197864.1
Compounds
  • cornexistin
Species Paecilomyces divaricatus [taxonomy]
References
Chemical products information
cornexistin
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C16H20O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ASK38699.1
  • pvL18
 26 - 3420 (+) putative nonribosomal peptide synthetase-like protein
  • Unknown
Sequence-based prediction
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  • ASK38700.1
  • pvL17
 3962 - 4990 (+) putative fumarylacetoacetate hydrolase
  • Unknown
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  • ASK38701.1
  • pvL16
 6530 - 7261 (-) hypothetical protein
  • Unknown
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  • ASK38702.1
  • pvL15
 8347 - 9393 (-) putative aldo/keto reductase
  • Unknown
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  • ASK38703.1
  • pvL14
 11449 - 13371 (+) putative transketolase
  • Unknown
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  • ASK38704.1
  • pvL13
 14979 - 16613 (-) cytochrome P450
  • Tailoring (Hydroxylation)
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  • ASK38705.1
  • pvL12
 17137 - 18645 (+) major facilitator superfamily transporter
  • Transport
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  • ASK38706.1
  • pvL11
 19894 - 20845 (-) dienelactone hydrolase
  • Tailoring (Hydrolysis)
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  • ASK38707.1
  • pvL10
 21179 - 22777 (-) major facilitator superfamily transporter
  • Transport
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  • ASK38708.1
  • pvL9
 23323 - 25562 (+) putative serine carboxypeptidase
  • Unknown
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  • ASK38709.1
  • pvL8
 25765 - 27237 (-) C6 transcription factor
  • Regulation
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  • ASK38710.1
  • pvL7
 28909 - 30039 (+) putative gluconolactonase
  • Unknown
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  • ASK38711.1
  • pvL6
 30414 - 32011 (-) citrate synthase-like protein
  • Tailoring (Unknown)
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  • ASK38712.1
  • pvL5
 33721 - 34814 (+) dioxygenase
  • Tailoring (Hydroxylation)
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  • ASK38713.1
  • pvL4
 36452 - 38034 (-) major facilitator superfamily transporter
  • Transport
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  • ASK38714.1
  • pvL3
 38429 - 39284 (+) ketosteroid isomerase-like protein
  • Tailoring (Unknown)
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  • ASK38715.1
  • pvL2
 39996 - 41525 (-) 2-methylcitrate dehydratase
  • Tailoring (Dehydration)
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  • ASK38716.1
  • pvL1
 42010 - 42823 (+) hydrolase 341
  • Other enzymatic
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  • ASK38717.1
  • pvpks1
 43533 - 51315 (+) polyketide synthase
  • Scaffold biosynthesis
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  • ASK38718.1
  • pvR1
 51716 - 52424 (-) PEBP-like protein
  • Other enzymatic
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  • ASK38719.1
  • pvR2
 55167 - 56534 (-) putative phosphotransferase
  • Unknown
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? no
Polyketide-synthases
Genes Properties Modules
pvpks1 Synthase subclass: Iterative type I
Iterative PKS type: Highly reducing, Unknown
Iteration counts: 3
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: HXVGKRLKDXN3R6A25AQJSXQH, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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