Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001436.1:
Cluster 1Polyketide158291

BGC0001436, cornexistin biosynthetic gene cluster from Paecilomyces divaricatus. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: cornexistin
SMILES string: Copy to clipboard
Molecular formula: C16H20O6
Exact molecular mass: 308.13 Da (None)
Molecular activity: Other

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
ASK38717.1
Iterative PKS subtype:
Highly reducing
3
Thioesterase type:
None
Release / cyclization type:
Unknown

Gene cluster description

cornexistin (BGC0001436). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank MF197864. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?unknown
Evidence for cluster-compound connection:Knock-out studies, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Katherine Williams (University of Bristol)

Literature references

1. Williams K et al. (2017) Genetic and chemical characterisation of the cornexistin pathway provides further insight into maleidride biosynthesis. Chem Commun (Camb) 53(56):7965-7968. doi: 10.1039/c7cc03303f.