BGC0001437: obafluorin biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 1 - 19,561 nt. (total: 19,561 nt).
This entry is originally from NCBI GenBank KX931446.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001437
Short description obafluorin biosynthetic gene cluster from Pseudomonas fluorescens
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KX931446.1
Compounds
  • obafluorin
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
obafluorin
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C17H14N2O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQZ26579.1
  • obaA
 452 - 1165 (+) ObaA
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  • AQZ26580.1
  • obaB
 1385 - 1894 (+) N-acylhomoserine lactone synthase
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  • AQZ26581.1
  • obaC
 1982 - 2932 (+) N-oxygenase
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  • AQZ26582.1
  • obaD
 2958 - 3557 (+) 4-Amino-4-deoxychorismate synthase component II
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  • AQZ26583.1
  • obaE
 3598 - 5058 (+) 4-Amino-4-deoxychorismate synthase component I
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  • AQZ26584.1
  • obaF
 5055 - 6317 (+) 4-Amino-4-deoxychorismate mutase/prephenate dehydrogenase
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  • AQZ26585.1
  • obaG
 6314 - 7636 (+) threonine transaldolase PLP-dependent
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  • AQZ26586.1
  • obaH
 7633 - 9336 (+) nitrophenylpyruvate decarboxylase ThDP-dependent
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  • AQZ26587.1
  • obaI
 9378 - 15110 (+) obafluorin dimodular nonribosomal peptide synthetase
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  • AQZ26588.1
  • obaJ
 15153 - 15797 (+) isochorismatase
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  • AQZ26589.1
  • obaK
 15794 - 16060 (+) obafluorin aryl carrier protein
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  • AQZ26590.1
  • obaL
 16057 - 16827 (+) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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  • AQZ26591.1
  • obaM
 16947 - 18020 (+) DAHP synthase
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  • AQZ26592.1
  • obaN
 18017 - 19435 (+) isochorismate synthase
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NRP-specific information
Subclass N/A
Cyclic? yes
Thioesterase genes
  • obaI (Type I)
NRP-synthases
Gene Modules
obaI
Module 0
Specificity: 2,3-dihydroxybenzoic acid
Evidence for specificity:
  • Structure-based inference
Module 1
Specificity: (2S,3R)-2-amino-3-hydroxy-4-(4-nitrophenyl)butanoic acid
Evidence for specificity:
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: SOJ5J6FNXPWDFJNGJGPS2QRA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Merged annotations from duplicate entry BGC0001710
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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