Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001438.1:
Cluster 1Polyketide / Saccharide138315

BGC0001438, warkmycin biosynthetic gene cluster from Streptomyces sp. CS057. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Warkmycin CS1
SMILES string: Copy to clipboard
Molecular formula: C48H65NO22
Exact molecular mass: 1025.4341 Da ([M+NH4]+)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide / Saccharide
Polyketide subclass:
Angucycline (cyclic)
Polyketide synthase subclass:
Type II
Starter unit:
None
Polyketide synthase / ketosynthase-encoding genes:

Saccharide subclass:
hybrid/tailoring
Glycosyltransferases:
B9W61_07190:
Specificity: Unknown
Evidence for specificity: Unknown
B9W61_07195:
Specificity: Unknown
Evidence for specificity: Unknown
B9W61_07205:
Specificity: Unknown
Evidence for specificity: Unknown
B9W61_07210:
Specificity: Unknown
Evidence for specificity: Unknown

Gene cluster description

warkmycin (BGC0001438). Gene Cluster 1. Biosynthetic class = Polyketide/Saccharide. GenBank KZ195572, positions 1756999-1795313. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Monica G. Malmierca (University of Oviedo)

Literature references

1. Helaly SE et al. (2013) Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930*. J Antibiot (Tokyo) 66(11):669-74. doi: 10.1038/ja.2013.74. Epub 2013