BGC0001441: belactosin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 27,983 nt. (total: 27,983 nt).
This entry is originally from NCBI GenBank KY249118.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001441
Short description belactosin A biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KY249118.1
via Knock-out studies, Enzymatic assays
Compounds
  • belactosin A
  • belactosin C
Species Streptomyces sp. [taxonomy]
References
Chemical products information
belactosin A Evidence: Mass spectrometry
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C17H27N3O6
Chemical database entries
NPAtlas
PubCHEM
belactosin C Evidence: Mass spectrometry
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C16H27N3O6
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARO49568.1
 1 - 348 (+) glyoxalase
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    • ARO49569.1
    • belA
    		 410 - 994 (-) acetyltransferase
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      • ARO49570.1
      • belB
      		 1052 - 1975 (-) peptidase U61
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        • ARO49571.1
        • belC
        		 1972 - 3921 (-) acyl-peptide hydrolase
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          • ARO49572.1
          • belD
          		 3942 - 5246 (-) acetyl-ornithine deacetylase
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            • ARO49573.1
            • belE
            		 5239 - 6072 (-) ABC transporter substrate-binding protein
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              • ARO49574.1
              • belF
              		 6194 - 6790 (-) 3-isopropylmalate dehydratase small subunit
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                • ARO49575.1
                • belG
                		 6802 - 8193 (-) 3-isopropylmalate dehydratase large subunit
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                  • ARO49576.1
                  • belH
                  		 8233 - 9708 (-) AMP-dependent synthetase
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                    • ARO49577.1
                    • belI
                    		 9708 - 10394 (-) SAM dependent methyltransferase
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                      • ARO49578.1
                      • belJ
                      		 10591 - 12288 (+) 2-IPM synthase
                      • Scaffold biosynthesis
                      • Knock-out
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                      • ARO49579.1
                      • belK
                      		 12542 - 13618 (+) Iron-containing redox enzyme
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                        • ARO49580.1
                        • belL
                        		 13654 - 14343 (+) BsmA domain containing protein
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                          • ARO49581.1
                          • belM
                          		 14340 - 15212 (+) diaminopimelate epimerase
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                            • ARO49582.1
                            • belN
                            		 15209 - 17296 (+) molybdopterin oxidoreductase
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                              • ARO49583.1
                              • belO
                              		 17384 - 18253 (-) LysR family transcription regulator
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                                • ARO49584.1
                                • belP
                                		 18359 - 18679 (-) LuxR family transcription regulator
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                                  • ARO49585.1
                                  • belQ
                                  		 19057 - 19932 (-) XRE family transcription regulator
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                                    • ARO49586.1
                                    • belR
                                    		 20619 - 21428 (+) methylesterase
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                                      • ARO49587.1
                                      • belS
                                      		 21425 - 22831 (+) MFS transporter
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                                        • ARO49588.1
                                        • belT
                                        		 23267 - 24319 (+) 1,4-beta-xylanase
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                                          • ARO49589.1
                                          • belU
                                          		 24574 - 25836 (-) ATP-dependent carboxylate-amide ligase
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                                            • ARO49590.1
                                            • belV
                                            		 26018 - 27187 (+) AMP-dependent synthetase
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                                              • ARO49591.1
                                              		 27264 - 27983 (-) SAM-dependent methyltransferase
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                                                Biosynthesis information
                                                Annotation changelog

                                                Entry version: 4

                                                Date
                                                Changes
                                                Submitters
                                                Reviewers
                                                2022-10-07
                                                Update chemical activity to schema version 2.11
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                Entry version: 3

                                                Date
                                                Changes
                                                Submitters
                                                Reviewers
                                                2022-09-15
                                                Updated bioactivity data
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                Entry version: 2

                                                Date
                                                Changes
                                                Submitters
                                                Reviewers
                                                2019-10-16
                                                Migrated from v1.4
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                2019-10-16
                                                Updated compound(s) information (NPAtlas curation)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                Entry version: 1

                                                Date
                                                Changes
                                                Submitters
                                                Reviewers
                                                2018-08-06
                                                Submitted
                                                • (ID: 4ACA66D6INRVNJRPWB3JQW5E)
                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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