BGC0001444 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001444 (Streptomyces sp. NTK 937)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	PKS-like	1	14,045	caboxamycin	other:shikimate-derived	100%

BGC0001444 - Region 1 - PKS-like

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Location: 1 - 14,045 nt. (total: 14,045 nt) Show pHMM detection rules used

Region on contig edge.

PKS-like: (t2pks2 or ksIII)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 14,046
Label		BGC0001444

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444	1.00	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0002493	0.27	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0000867	0.24	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0002474	0.24	NRP	agrobactin	Agrobacterium tumefaciens
BGC0002076	0.24	Other	4,5-didehydroacaterin, acaterin	Pseudomonas jessenii
BGC0001292	0.23	Other	A33853	Streptomyces sp. NRRL 12068
BGC0001850	0.22	Other (Shikimate-derived)	diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G	Streptomyces sp. F001
BGC0000343	0.21	NRP	enterobactin	Pseudomonas sp. J465
BGC0001928	0.21	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0002443	0.20	Polyketide	mycemycin C, mycemycin A, mycemycin B	Streptomyces olivaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444	1.00	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0002493	0.60	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0000867	0.58	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0002474	0.57	NRP	agrobactin	Agrobacterium tumefaciens
BGC0002076	0.57	Other	4,5-didehydroacaterin, acaterin	Pseudomonas jessenii
BGC0001292	0.57	Other	A33853	Streptomyces sp. NRRL 12068
BGC0001850	0.55	Other (Shikimate-derived)	diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G	Streptomyces sp. F001
BGC0000343	0.53	NRP	enterobactin	Pseudomonas sp. J465
BGC0001928	0.53	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0002443	0.52	Polyketide	mycemycin C, mycemycin A, mycemycin B	Streptomyces olivaceus

Similar known gene clusters from MIBiG 4.0

NRPS/PKS substrates

NRPS/PKS substrate predictions

DT87_23850

AMP-binding (32..445): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: pip (Hpr)

Stachelhaus prediction details:

Stachelhaus sequence:: TWPSQGVLTK
Nearest Stachelhaus code(s):: Hpa TWPSQGVLCK (88% 8Å match)
Stachelhaus code match:: 90% (moderate)