BGC0001446: asparasone A biosynthetic gene cluster from Aspergillus flavus NRRL3357
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 2,642,293 - 2,658,105 nt. (total: 15,813 nt).
This entry is originally from NCBI GenBank EQ963472.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001446
Short description asparasone A biosynthetic gene cluster from Aspergillus flavus NRRL3357
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: EQ963472.1
Compounds
  • asparasone A
Species Aspergillus flavus NRRL3357 [taxonomy]
References
Chemical products information
asparasone A
Copy SMILES
C18H14O8
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFLA_082140
  • EED57517.1
 2642293 - 2642633 (-) hypothetical protein
  • Regulation
Knock-out
copy AA seq
copy Nt seq
  • AFLA_082150
  • EED57518.1
 2646293 - 2652837 (+) polyketide synthase, putative
  • Scaffold biosynthesis
Knock-out
copy AA seq
copy Nt seq
  • AFLA_082160
  • EED57519.1
 2653373 - 2655374 (-) MFS glucose transporter, putative
copy AA seq
copy Nt seq
  • AFLA_082170
  • EED57520.1
 2656834 - 2658105 (-) efflux pump antibiotic resistance protein, putative
copy AA seq
copy Nt seq
Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? no
Polyketide-synthases
Genes Properties Modules
AFLA_082150 Synthase subclass: Iterative type I
Iterative PKS type: Non-reducing, Unknown
Iteration counts: 8
Module 1
Genes: AFLA_082150
Core domains: Ketosynthase, Acyltransferase, Thiolation (ACP/PCP), Thioesterase
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: YBVE4IRPJQLTEDBWA2WPXAKO, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed gene names of 'No gene ID'
  • Removed ketoreductase stereochemistry annotation from modules without ketoreductases
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.