BGC0001446: asparasone A biosynthetic gene cluster from Aspergillus flavus NRRL3357
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Location: 2,642,293 - 2,658,105 nt. (total: 15,813 nt).
This entry is originally from NCBI GenBank EQ963472.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001446
Short description asparasone A biosynthetic gene cluster from Aspergillus flavus NRRL3357
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
EQ963472.1
2642293 - 2658105
via Knock-out studies
Compounds
  • asparasone A
Species Aspergillus flavus NRRL3357 [taxonomy]
References
Chemical products information
asparasone A Evidence: Mass spectrometry
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C18H14O8
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFLA_082140
  • EED57517.1
 2642293 - 2642633 (-) hypothetical protein
  • Regulation
  • Knock-out
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  • AFLA_082150
  • EED57518.1
 2646293 - 2652837 (+) polyketide synthase, putative
  • Scaffold biosynthesis
  • Knock-out
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  • AFLA_082160
  • EED57519.1
 2653373 - 2655374 (-) MFS glucose transporter, putative
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    • AFLA_082170
    • EED57520.1
    		 2656834 - 2658105 (-) efflux pump antibiotic resistance protein, putative
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      Biosynthesis information

      Biosynthetic modules

      Name
      1
      Type
      pks-modular
      Genes
      AFLA_082150
      Substrates
      Integrated Monomers
      Domains
      acyltransferase, ketosynthase, acyltransferase, thioesterase, carrier (ACP)
      Annotation changelog

      Entry version: 4

      Date
      Changes
      Submitters
      Reviewers
      2022-10-07
      Update chemical activity to schema version 2.11
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 3

      Date
      Changes
      Submitters
      Reviewers
      2022-09-15
      Removed gene names of 'No gene ID'
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      2022-09-15
      Removed ketoreductase stereochemistry annotation from modules without ketoreductases
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 2

      Date
      Changes
      Submitters
      Reviewers
      2019-10-16
      Migrated from v1.4
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      2019-10-16
      Updated compound(s) information (NPAtlas curation)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 1

      Date
      Changes
      Submitters
      Reviewers
      2018-08-06
      Submitted
      • (ID: YBVE4IRPJQLTEDBWA2WPXAKO)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      Detailed domain annotation
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