LOCUS       BGC0001449             42501 bp    DNA     linear   PLN 02-SEP-2014
DEFINITION  Myceliophthora thermophila ATCC 42464 chromosome 3, complete
            sequence.
ACCESSION   BGC0001449
VERSION     BGC0001449
KEYWORDS    .
SOURCE      Thermothelomyces thermophilus ATCC 42464
  ORGANISM  Thermothelomyces thermophilus ATCC 42464
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae;
            Thermothelomyces.
COMMENT     URL -- http://www.jgi.doe.gov/fungi
            JGI Project ID: 4043098
            The DNA was provided by Adrian Tsang (tsang@gene.concordia.ca)
            The strain is available from the American Type Culture Collection
            under ATCC 42464
            Contacts: Adrian Tsang (tsang@gene.concordia.ca)
            Igor Grigoriev (ivgrigoriev@lbl.gov)
            Assembly and annotation done by JGI.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 01:43:26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1174999
            Orig. end    :: 1217500
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..42501
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="NRP, Polyketide, Alkaloid"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..42501
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(598..1989)
                     /locus_tag="MYCTH_2303693"
                     /product="hypothetical protein"
     gene            complement(598..1989)
                     /locus_tag="MYCTH_2303693"
     CDS             complement(899..1864)
                     /codon_start=1
                     /db_xref="JGIDB:Spoth2_2303693"
                     /locus_tag="MYCTH_2303693"
                     /product="hypothetical protein"
                     /protein_id="AEO57479.1"
                     /transl_table=1
                     /translation="MHPKRTYFLAPTRDQAPTGPIALGNLIRSPREPDFPLNDPNSPTV
                     RRLQSAATVVPEADATRSAHAARSLQPTVFLSFLSGLLGQNPVELSVAYSTAGGAAYRI
                     PRLETRTIHPSAADVAALFAEPAVQAALRDSRFTANLYLVTGLQIATHGAEYLVSGARA
                     RGVRLHFLTDLITTAAGGVPVGAGVGAEATEAMEGRSAGRIEGPFVLAYSLREVLYRRK
                     KVTGQRRPRIEGDLYADGERKVRIIKREEEEEEEEEEEEEGQVESFEAELAGLKDEDPE
                     LPEYWDLIDVETGVDLDGAECQIVRVAADKHDGDDDLDED"
     mRNA            join(3776..4552,4633..4963,5070..5834,5925..6286)
                     /locus_tag="MYCTH_2303695"
                     /product="hypothetical protein"
     gene            3776..6286
                     /locus_tag="MYCTH_2303695"
     CDS             join(4002..4552,4633..4963,5070..5828)
                     /codon_start=1
                     /db_xref="InterPro:IPR000209"
                     /db_xref="JGIDB:Spoth2_2303695"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 100.8; E-value: 1.8e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_2303695"
                     /note="GO_function: GO:4289 - subtilase activity;
                     GO_process: GO:6508 - proteolysis"
                     /product="hypothetical protein"
                     /protein_id="AEO57480.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.7e-17, bitscore:
                     52.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLQIRKAQTVPIPVGRSERRQIEALPTFAPGTLIFLNHDPASEGR
                     LSASATSLVVQETRARSSSTGRALPESASLREPYDKEHRESRSSPPTKSSDRDLASEST
                     PSEDTLGEQRSKTLEESGPKPVLVNARKQDTEELGSGVDNPILIPSGVNPGPPKESEPK
                     SSVVNKGSISDATQQLVDDTSVDIWFGDIEKINEEILEPYRRQACKRVKVGILDTGIDM
                     KNTAFHKAEVRQRIKKRVDFCDPNGKGTGRDKCGHGTHCAALINRIAPAADIYVGRVAI
                     DFDSGVDENVVAKAITIALGSRGPGDASNNWDVDILSLSLGFQHYSEAIDTALRTSTRK
                     GKIVLAAASNNGTLRAMAYPAWDPDVIPINSANARGRPSDFNPPAVPGRTLTILGENVP
                     SAWITTTPTATTTASTTDMSGPDDAGAPEAAAAAVDLAATRRMSGTSVATPIAAGLVAL
                     LFEFAMVEVPNDPVTQATLNDVLPNIKRQTGLNALLMGKAARTGDFHNIVPMNLLNPNL
                     TLGENAAVIKGVLARWFGFRRPIKGTDGV"
     aSDomain        complement(6826..7485)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_TD.1"
                     /evalue="3.80E-51"
                     /label="MYCTH_68164_TD.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3948"
                     /protein_start="3728"
                     /score="165.5"
                     /tool="antismash"
                     /translation="ALTGASGFLGLELVRQLVRLPEVKTVHALAVRSQSKLAQVSSPKL
                     VIHPGDLSKPQLGLTDTAATEVFKTSHAVIHNGADVSFLKAYGSVRRTNLESTKDIVKL
                     ALQHGNVRHLHYISTAGIATMLGHDLYEESLGAFPPTSSPEGYVLSKWASELYLERASA
                     VTGLPVTIHRPTAIVGENAPHLDVMSNILHYSRQMATVPSMSALEGTFQFVPVEDVA"
     aSModule        6826..10966
                     /complete
                     /domains="nrpspksdomains_MYCTH_68164_Condensation_LCL.1"
                     /domains="nrpspksdomains_MYCTH_68164_AMP-binding.1"
                     /domains="nrpspksdomains_MYCTH_68164_PP-binding.1"
                     /domains="nrpspksdomains_MYCTH_68164_TD.1"
                     /final_module
                     /locus_tags="MYCTH_68164"
                     /tool="antismash"
                     /type="nrps"
     mRNA            complement(join(<6826..8997,9070..9581,9640..11541,
                     11614..12320,12398..18501,18577..>19023))
                     /locus_tag="MYCTH_68164"
                     /product="polyketide synthetase"
     gene            complement(<6826..>19023)
                     /locus_tag="MYCTH_68164"
     CDS             complement(join(<6826..8997,9070..9581,9640..11541,
                     11614..12320,12398..18501,18577..19023))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (10-438). E-value:
                     1.4e-168. Score: 553.0. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (545-863). E-value: 1.1e-89.
                     Score: 292.5. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (937-1124). E-value: 1e-23.
                     Score: 76.3. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1389-1593). E-value: 7.4e-49.
                     Score: 157.7. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2128-2303). E-value: 2.1e-49.
                     Score: 159.8. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2417-2493). E-value: 9.5e-11.
                     Score: 33.8. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2611-2902). E-value:
                     1.8e-69. Score: 225.9. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3068-3475). E-value:
                     2.9e-74. Score: 241.9. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3617-3684). E-value:
                     7.7e-14. Score: 43.9. Matches aSDomain:
                     nrpspksdomains_MYCTH_68164_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3728-3948). E-value: 3.8e-51. Score:
                     165.5. Matches aSDomain: nrpspksdomains_MYCTH_68164_TD.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="JGIDB:Spoth2_68164"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 217.1; E-value:
                     7.2e-66)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MYCTH_68164"
                     /note="polyketide synthase/non-ribosomal peptide synthetase
                     hybrid; GO_function: GO:3824; cofactor binding - catalytic
                     activity [PMID 48037]; GO_process: GO:8152 - metabolic
                     process"
                     /product="PKS-NRPSs"
                     /protein_id="AEO57481.1"
                     /sec_met_domain="Condensation (E-value: 1.3e-52, bitscore:
                     168.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-76, bitscore:
                     247.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-14, bitscore:
                     43.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.6e-90, bitscore: 292.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 8.7e-173, bitscore:
                     564.6, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.3e-42, bitscore:
                     134.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.7e-40, bitscore:
                     128.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSSAQAKSEPIAIIGSGCRFPGSASSPSKLWDLLSKPRDVLSEIP
                     RSRFDPHGFYNPVGDTSGHSNVLHSYVLDEDVRAWDADFFNISANEAAAIDPQQRLLME
                     TVYEALEAAGQRIGDLRGSDTAVYVGLMGEEYSSIQGRELDMMPTYHATGTARSIVSNR
                     ISYFFDWHGPSMTIDTACSSSLVAVHQCVQQLRAGHSRMAVAAGTNLLLGPEPYISEST
                     FHMLSPRGRSHMWDAEADGYGRGDGVAAVVLKKLSDAIADGDPIECIIRETGVNQDGRT
                     GGITVPSPDAQVALIEDTYRRAGLDLSSPSDRPQYFEAHGTGTATGDPLEAEAIHRAIG
                     SRLGPGEKLYVGSVKTIIGHTEGTAGIAGLMKASLALQNRLIPPNLLFKTLNPRIEPFY
                     KGLEVPVKAREWPEGAPKRASVNSFGFGGTNAHAILERYEPPTALPRAEMGIVARVWTF
                     TFSAASKASLSQALRNTADFLGQSPNISARDLAYTLNSRRSTFPYRVAYVARDVEGLRK
                     RVLDSVGSPEWETQAVVRPPNRPMKILGIFTGQGAQWPGMGKQLLEASPFAQARIQELE
                     LALATLPAADRPSWSLREELVAEGSKSKLHLAEYAQPLCTALQILLVDLLTAANVKFSA
                     VVGHSSGEIGAAYAAGVLSARDAIVTAYYRGVHTKLAGGPDGQRGAMLAVGTSPEDAED
                     FVSLPRFEGRIGIAACNSPTSVTLSGDADAIEEAKEVFEDESKFARALRVDKAYHSHHM
                     RPCSDPYVASLRKAGVTANKPRDGCKWYSSVHDGAVLTGHANEELDSVYWARNMAQTVL
                     FSTAVESACAEEQYTIAIEVGPHGTLKGPALDTMKAVTKSVPAYISCLSRNSDSSEAFA
                     NAIGQIWANAADGALDLDKYHITAHGLSGARPSIIKDLPTYPWDNKRVFWNESRRSRAL
                     RLRTEPGHPLLGILSPDSNDTDLSWHTVLRLSNLPWISGHQLQGQTVFPAAGYVALAAE
                     AAKQLAKAAAAGPLAKIELKDLDIGKAIAFESDKAGIELVFSLHIDKATEIDGHRVFET
                     SFFARSVTATAESTDAALNASGRMQVTVAGDGAAEPLESLPAQEAGPAAMTEVDDSLFY
                     SELKQLGYGYSGAFRALHSMTRKSDFGRGRISKVDAASMHPSEKDLLVHPGYLDAAFQA
                     MFLAYSYPGDGRIWSLHVPVSIKSIRIDAARCRANSDDYLSFDAAINAAESLSGKIDLS
                     GDVDIFSGDGRTGLIQVENIRLIPFAPATESQDTQMFYVNTWNTASPDGAIAAGDNRAS
                     QEDNELGWLLERVAHFYLRNLAESIRPDEEAGARWHHKKLLEFARQSVALARGGRQRFF
                     KKEWLRDTAETLEPLMDAFGDRVDVQLLRNVGEHLADAVRGQGDILTHMTKDGLLDRWY
                     EESLGLGEYTGFLAEVVGQITHVNPHVRILEVGGRSGNATKKILKRASHAFSHYTFTDV
                     SPDAVEAAKSLFPDYQGRMSFQVLELGADLAEQGFQAHSYDLVIGVLALHTWPQDPEAY
                     LSNLHQLLKPGGYLALLEATSGATVRLPAMMGGLEGWWPAKNRGRGSTKRLSAAEWHAA
                     LVQAGFSGIETSTPELDVLPRPYSVLVSRATNEHIDLLLEPSSKNDASALSHIDELVIV
                     SGRSLVSVRLAEKMRRLLELHSERITVVPAAQDLASLDLSARPTVLYLADLDEPVFTRY
                     TPEAHDGLKKLWTTAQTVLWATRGARRDNPHAIMSLGLGRAMMVEQAHAKINVQFIDFA
                     VDARLDAHMLVDELLRLQILGRLARESADFVWVKEPEFEVDAEGRKWVPRIVPHQATND
                     RYNSSRRQIVAEADPAKEVVEVVESHDDNNGSQNRALIRVLAPEARRTDGEEVTRVRVL
                     YSATVPLRPSSSQALYPFIGLDTATDAPVVALAKSIASIVEVPASSVVPYNYPLDEAPS
                     RLRAITSHLLASLICSEAATVDGTTLLVDPDDDLAESVAKLAGEKRLSVTSVTTSPASK
                     RAYPGVSVSAHASSRTIRRALPPRIASVIDFTKPSSWRGNFVAQIKALLPDAARFEKAS
                     SFQARNFSTTALAALCQEAVHLAPTNLSKSGAVSADAYVADPQSSAASVIDWTASSSVS
                     VSVKPSDALPIFRGDRTYVLFGLAGAGGLGLPLAEYMVSLGARYIVLTSRRPSVDPHLI
                     AEYAAKGVQIKAVKNDITDENDVRSLIADLRSSWPPIAGVANGANVLNDMSFEDMTFDD
                     MNKVLRPKVEGTRILDQIFYDDPLDFFIGFSSISIVLGRAGQSNYDTANIYMLGLASQR
                     RARGLNASVIDIGPIAGVGLMARDVSENVMNLLVSHGYRKMSGRDFLATFTNGILMGRV
                     DSREPEELITGLTVHPKKGKFQPTWVDNARFSHLLLNTDGASGASSEGSAQVESLEDLL
                     KRARSPGDVGRVLRVAVLNKLQNILSLSDELVNNPDALLQQGTSALGLDSLLAVELRTW
                     MRSELGVDIPVLKILSDTPVQGLVDYAVENLPAEYVPNLDPNGKDAITEESLTAPKAKE
                     EHPKPVAASVPPAAPPVATTTKPNGSPTLPSVPSSASETEAPTPTGSSSPASSVADPTE
                     STSLVAPPSSQPVSLSPSLTISQSPAIEKVLPMSFGQSRFWVMTQIVQDPTAFNISCDV
                     EIQSEIDVRALSRAVEMVGARHEALRTCFFHEDDQPMQAILKESPLRLETVSASVSDID
                     RLFQEVHNTVYDLSKGETMRAMLVSTSRTHHHLLVGYHHINMDSSSFVVFVADMIKIYA
                     GQKLSPPRMQYSDFSKYQVEQLSKGNWDSLIAYWSNEFARLPDPLPILNVSPNTSRPRP
                     NLTTYENRSIETRVSASVARQVKSACRKLKVTPFHIYTTILQITLARLAATDDICIGIA
                     DANRADVGATDSIGNFLNLIPLRLPTDLNLPFSSLVKATKNKVLHGLANSAVPFDVIME
                     KVGVQRSSTHSPLFQAFIDYRYVTEKLPFGKGHLEGKRYIVSKTPYDVMIEMIDTPTGE
                     ASLKLLTQEALYTPEESQTIMGCYTTLLDAFTKDTELAAGQPQMFDAGEVNRALQLGKG
                     EFLDLQHPTILTEVDETAAQQPGAVALRDSQGNSLSWSDLKLRSVAIGQSLVNLGLPAR
                     SRIGVFQEPDVDWVCSMLGVWRAEKTYVPLETTQGVRRLADVAKEAKLAAVLVHDPTVP
                     LVSQLALDDTVKVINVSTLPFNRLAATSFVSNHKPSDEAMIIYTSGSTGVPKGISIAHR
                     VVVNAARSFLHRWPMSPQTVLQQTPLSFDVSWWGAIIALATKGTVVVAGPEARRDPRAL
                     TDLIVSKKVTFTFAVPSESVAWLQGGDLAALRSSAWTWHCSGGEPYSQNLINHLRLLDK
                     PDLRAINIYGPTETMIPNAYEVLYRSFSASDMPVPIGRVMPNYTARVVDAQGHPVPAGI
                     PGQLLFAGAGIADGYVGNPELTAERFPEDDLAPAEFVKQGWKLVHHSGDSGYLRESDGQ
                     FILQARINGDTQVKLRGLRIDMLDIEAQLLSTAKGLVSDAVVHVRKPEPNNSSADFLAA
                     HVVLSEEGRARYATPAEQETFLDKVVAELRVPDYMRPAVIVAVTSLPLTHHGKVDRKAV
                     AKLPLTRALGKATETPVGAAAAVDLGGNENLNKMKDLWLNVLGESVHAHTLGPNSDFFL
                     VGGNSLLLIRVQGDLRKQYGLDVPLTQLFQRNTLAQMASLLDGKDRNNASATSGIDWPR
                     EIKLQPALSHLRAPASPMPKSGLVIALTGASGFLGLELVRQLVRLPEVKTVHALAVRSQ
                     SKLAQVSSPKLVIHPGDLSKPQLGLTDTAATEVFKTSHAVIHNGADVSFLKAYGSVRRT
                     NLESTKDIVKLALQHGNVRHLHYISTAGIATMLGHDLYEESLGAFPPTSSPEGYVLSKW
                     ASELYLERASAVTGLPVTIHRPTAIVGENAPHLDVMSNILHYSRQMATVPSMSALEGTF
                     QFVPVEDVA"
     CDS_motif       complement(7429..7482)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0015"
                     /evalue="4.30E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3747"
                     /protein_start="3729"
                     /score="3.4"
                     /tool="antismash"
                     /translation="LTGASGFLGLELVRQLVR"
     aSDomain        complement(7618..7818)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PP-binding.1"
                     /evalue="7.70E-14"
                     /label="MYCTH_68164_PP-binding.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3684"
                     /protein_start="3617"
                     /score="43.9"
                     /tool="antismash"
                     /translation="KMKDLWLNVLGESVHAHTLGPNSDFFLVGGNSLLLIRVQGDLRKQ
                     YGLDVPLTQLFQRNTLAQMASL"
     CDS_motif       complement(8191..8241)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0014"
                     /evalue="5.00E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3493"
                     /protein_start="3476"
                     /score="12.9"
                     /tool="antismash"
                     /translation="DTQVKLRGLRIDMLDIE"
     aSDomain        complement(join(8245..8997,9070..9537))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_AMP-binding.1"
                     /evalue="2.90E-74"
                     /label="MYCTH_68164_AMP-binding.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3475"
                     /protein_start="3068"
                     /score="241.9"
                     /tool="antismash"
                     /translation="DETAAQQPGAVALRDSQGNSLSWSDLKLRSVAIGQSLVNLGLPAR
                     SRIGVFQEPDVDWVCSMLGVWRAEKTYVPLETTQGVRRLADVAKEAKLAAVLVHDPTVP
                     LVSQLALDDTVKVINVSTLPFNRLAATSFVSNHKPSDEAMIIYTSGSTGVPKGISIAHR
                     VVVNAARSFLHRWPMSPQTVLQQTPLSFDVSWWGAIIALATKGTVVVAGPEARRDPRAL
                     TDLIVSKKVTFTFAVPSESVAWLQGGDLAALRSSAWTWHCSGGEPYSQNLINHLRLLDK
                     PDLRAINIYGPTETMIPNAYEVLYRSFSASDMPVPIGRVMPNYTARVVDAQGHPVPAGI
                     PGQLLFAGAGIADGYVGNPELTAERFPEDDLAPAEFVKQGWKLVHHSGDSGYLRESDGQ
                     FILQARIN"
     CDS_motif       complement(8368..8457)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0013"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3434"
                     /protein_start="3404"
                     /score="37.1"
                     /tool="antismash"
                     /translation="PAGIPGQLLFAGAGIADGYVGNPELTAERF"
     CDS_motif       complement(join(8980..8997,9070..9111))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0012"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="MYCTH_68164"
                     /protein_end="3230"
                     /protein_start="3210"
                     /score="23.2"
                     /tool="antismash"
                     /translation="AMIIYTSGSTGVPKGISIAH"
     CDS_motif       complement(9941..10048)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0011"
                     /evalue="9.50E-10"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2953"
                     /protein_start="2917"
                     /score="30.8"
                     /tool="antismash"
                     /translation="NKVLHGLANSAVPFDVIMEKVGVQRSSTHSPLFQAF"
     aSDomain        complement(10094..10966)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.80E-69"
                     /label="MYCTH_68164_Condensation_LCL.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2902"
                     /protein_start="2611"
                     /score="225.9"
                     /tool="antismash"
                     /translation="VLPMSFGQSRFWVMTQIVQDPTAFNISCDVEIQSEIDVRALSRAV
                     EMVGARHEALRTCFFHEDDQPMQAILKESPLRLETVSASVSDIDRLFQEVHNTVYDLSK
                     GETMRAMLVSTSRTHHHLLVGYHHINMDSSSFVVFVADMIKIYAGQKLSPPRMQYSDFS
                     KYQVEQLSKGNWDSLIAYWSNEFARLPDPLPILNVSPNTSRPRPNLTTYENRSIETRVS
                     ASVARQVKSACRKLKVTPFHIYTTILQITLARLAATDDICIGIADANRADVGATDSIGN
                     FLNLIPLRLP"
     CDS_motif       complement(10100..10189)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0010"
                     /evalue="4.20E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2900"
                     /protein_start="2870"
                     /score="16.1"
                     /tool="antismash"
                     /translation="DICIGIADANRADVGATDSIGNFLNLIPLR"
     CDS_motif       complement(10790..10903)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0009"
                     /evalue="8.60E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2670"
                     /protein_start="2632"
                     /score="37.5"
                     /tool="antismash"
                     /translation="TAFNISCDVEIQSEIDVRALSRAVEMVGARHEALRTCF"
     aSDomain        complement(join(11321..11541,11614..11620))
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PKS_PP.1"
                     /evalue="9.50E-11"
                     /label="MYCTH_68164_PKS_PP.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2493"
                     /protein_start="2417"
                     /score="33.8"
                     /tool="antismash"
                     /translation="LRVAVLNKLQNILSLSDELVNNPDALLQQGTSALGLDSLLAVELR
                     TWMRSELGVDIPVLKILSDTPVQGLVDYAVE"
     aSModule        11321..18993
                     /complete
                     /domains="nrpspksdomains_MYCTH_68164_PKS_KS.1"
                     /domains="nrpspksdomains_MYCTH_68164_PKS_AT.1"
                     /domains="nrpspksdomains_MYCTH_68164_PKS_DH.1"
                     /domains="nrpspksdomains_MYCTH_68164_cMT.1"
                     /domains="nrpspksdomains_MYCTH_68164_PKS_KR.1"
                     /domains="nrpspksdomains_MYCTH_68164_PKS_PP.1"
                     /iterative
                     /locus_tags="MYCTH_68164"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(11963..12320,12398..12564))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PKS_KR.1"
                     /evalue="2.10E-49"
                     /label="MYCTH_68164_PKS_KR.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2303"
                     /protein_start="2128"
                     /score="159.8"
                     /tool="antismash"
                     /translation="VLFGLAGAGGLGLPLAEYMVSLGARYIVLTSRRPSVDPHLIAEYA
                     AKGVQIKAVKNDITDENDVRSLIADLRSSWPPIAGVANGANVLNDMSFEDMTFDDMNKV
                     LRPKVEGTRILDQIFYDDPLDFFIGFSSISIVLGRAGQSNYDTANIYMLGLASQRRARG
                     LNASVIDIGPIA"
     CDS_motif       complement(12008..12118)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0008"
                     /evalue="7.10E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2288"
                     /protein_start="2251"
                     /score="44.3"
                     /tool="antismash"
                     /translation="LDFFIGFSSISIVLGRAGQSNYDTANIYMLGLASQRR"
     CDS_motif       complement(12466..12546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0007"
                     /evalue="4.10E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="2161"
                     /protein_start="2134"
                     /score="29.0"
                     /tool="antismash"
                     /translation="GAGGLGLPLAEYMVSLGARYIVLTSRR"
     aSDomain        complement(14170..14781)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="7.40E-49"
                     /label="MYCTH_68164_cMT.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="1593"
                     /protein_start="1389"
                     /score="157.7"
                     /tool="antismash"
                     /translation="THMTKDGLLDRWYEESLGLGEYTGFLAEVVGQITHVNPHVRILEV
                     GGRSGNATKKILKRASHAFSHYTFTDVSPDAVEAAKSLFPDYQGRMSFQVLELGADLAE
                     QGFQAHSYDLVIGVLALHTWPQDPEAYLSNLHQLLKPGGYLALLEATSGATVRLPAMMG
                     GLEGWWPAKNRGRGSTKRLSAAEWHAALVQAGFSGIETSTP"
     aSDomain        complement(15577..16137)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PKS_DH.1"
                     /evalue="1.00E-23"
                     /label="MYCTH_68164_PKS_DH.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="1124"
                     /protein_start="937"
                     /score="76.3"
                     /tool="antismash"
                     /translation="HPLLGILSPDSNDTDLSWHTVLRLSNLPWISGHQLQGQTVFPAAG
                     YVALAAEAAKQLAKAAAAGPLAKIELKDLDIGKAIAFESDKAGIELVFSLHIDKATEID
                     GHRVFETSFFARSVTATAESTDAALNASGRMQVTVAGDGAAEPLESLPAQEAGPAAMTE
                     VDDSLFYSELKQLGYGYSGAFRAL"
     CDS_motif       complement(15976..16053)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0006"
                     /evalue="2.90E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="MYCTH_68164"
                     /protein_end="991"
                     /protein_start="965"
                     /score="32.6"
                     /tool="antismash"
                     /translation="WISGHQLQGQTVFPAAGYVALAAEAA"
     aSDomain        complement(16360..17313)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PKS_AT.1"
                     /evalue="1.10E-89"
                     /label="MYCTH_68164_PKS_AT.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="863"
                     /protein_start="545"
                     /score="292.5"
                     /tool="antismash"
                     /translation="IFTGQGAQWPGMGKQLLEASPFAQARIQELELALATLPAADRPSW
                     SLREELVAEGSKSKLHLAEYAQPLCTALQILLVDLLTAANVKFSAVVGHSSGEIGAAYA
                     AGVLSARDAIVTAYYRGVHTKLAGGPDGQRGAMLAVGTSPEDAEDFVSLPRFEGRIGIA
                     ACNSPTSVTLSGDADAIEEAKEVFEDESKFARALRVDKAYHSHHMRPCSDPYVASLRKA
                     GVTANKPRDGCKWYSSVHDGAVLTGHANEELDSVYWARNMAQTVLFSTAVESACAEEQY
                     TIAIEVGPHGTLKGPALDTMKAVTKSVPAYISCLSRN"
     CDS_motif       complement(16972..17052)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0005"
                     /evalue="1.90E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="MYCTH_68164"
                     /protein_end="659"
                     /protein_start="632"
                     /score="30.0"
                     /tool="antismash"
                     /translation="FSAVVGHSSGEIGAAYAAGVLSARDAI"
     CDS_motif       complement(17263..17313)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0004"
                     /evalue="1.20E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="562"
                     /protein_start="545"
                     /score="17.7"
                     /tool="antismash"
                     /translation="IFTGQGAQWPGMGKQLL"
     aSDomain        complement(join(17635..18501,18577..18993))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_68164_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="1.40E-168"
                     /label="MYCTH_68164_PKS_KS.1"
                     /locus_tag="MYCTH_68164"
                     /protein_end="438"
                     /protein_start="10"
                     /score="553.0"
                     /tool="antismash"
                     /translation="IAIIGSGCRFPGSASSPSKLWDLLSKPRDVLSEIPRSRFDPHGFY
                     NPVGDTSGHSNVLHSYVLDEDVRAWDADFFNISANEAAAIDPQQRLLMETVYEALEAAG
                     QRIGDLRGSDTAVYVGLMGEEYSSIQGRELDMMPTYHATGTARSIVSNRISYFFDWHGP
                     SMTIDTACSSSLVAVHQCVQQLRAGHSRMAVAAGTNLLLGPEPYISESTFHMLSPRGRS
                     HMWDAEADGYGRGDGVAAVVLKKLSDAIADGDPIECIIRETGVNQDGRTGGITVPSPDA
                     QVALIEDTYRRAGLDLSSPSDRPQYFEAHGTGTATGDPLEAEAIHRAIGSRLGPGEKLY
                     VGSVKTIIGHTEGTAGIAGLMKASLALQNRLIPPNLLFKTLNPRIEPFYKGLEVPVKAR
                     EWPEGAPKRASVNSFGFGGTNAHAILERY"
     CDS_motif       complement(17956..18003)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0003"
                     /evalue="3.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="MYCTH_68164"
                     /protein_end="331"
                     /protein_start="315"
                     /score="10.3"
                     /tool="antismash"
                     /translation="YFEAHGTGTATGDPLE"
     CDS_motif       complement(18208..18246)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0002"
                     /evalue="1.10E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="MYCTH_68164"
                     /protein_end="247"
                     /protein_start="234"
                     /score="9.3"
                     /tool="antismash"
                     /translation="WDAEADGYGRGDG"
     CDS_motif       complement(18388..18435)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_68164_0001"
                     /evalue="5.10E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="MYCTH_68164"
                     /protein_end="187"
                     /protein_start="171"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     mRNA            join(<20043..20417,20489..>20935)
                     /locus_tag="MYCTH_50128"
                     /note="Has EST support"
                     /product="methyltransferase-like protein"
     gene            <20043..>20935
                     /locus_tag="MYCTH_50128"
     CDS             join(<20043..20417,20489..20935)
                     /codon_start=1
                     /db_xref="InterPro:IPR013216"
                     /db_xref="JGIDB:Spoth2_50128"
                     /locus_tag="MYCTH_50128"
                     /note="GO_function: GO:8168 - methyltransferase activity;
                     GO_process: GO:8152 - metabolic process"
                     /product="methyltransferase-like protein"
                     /protein_id="AEO57482.1"
                     /transl_table=1
                     /translation="KAGDWDRFAETYKQITESTNIKPVGAILDRLNALWPFKDATGFLD
                     NGCGPGTIMARLIDVYGTSLPPSCSLLCTDYSPAMIKQVEAAREKQEPASLWARVDARV
                     LDALDLRGIGDNSLSHVAAGLLYNLTTDPHKCLTECRRVLQPNGVLAASAWEGNEWLEM
                     MQVLPIIKPELKSAVKAKWTSVSAMKADLAAAGFRDVEVESVPVQVPFESHDLFVDTLL
                     TYQPRMTALLRDFTEQEKATLRKLLIEEMKVYCPTEPGALNGVVLVATGCK"
     mRNA            join(22108..22332,22412..22576,22675..>23358)
                     /locus_tag="MYCTH_115957"
                     /product="2OG-Fe(II) oxygenase-like protein"
     gene            22108..>23358
                     /locus_tag="MYCTH_115957"
     CDS             join(22174..22332,22412..22576,22675..23358)
                     /codon_start=1
                     /db_xref="InterPro:IPR005123"
                     /db_xref="JGIDB:Spoth2_115957"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_115957"
                     /product="2OG-Fe(II) oxygenase-like protein"
                     /protein_id="AEO57483.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 2.1e-15, bitscore:
                     47.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPVPLLDASQVRAGPEARKSFLRDLIQSFQDYGFVRLTNHGIPPA
                     RVKEMFELAGELFSLDTETKLGFANIADGSPQRGYSAIGVEKTASLHGKLIGRNVDERL
                     TDAREHFDCGSPLDEEYRNRWPQSESLGYFRKEMEAFYFEMEQVTAELLSWLEEGLGVP
                     RGTFNNLVTHEKNASELRLNHYPPVPASQLLSGQVSRIWPHFDLGVITLLFTSGVGGLE
                     VEDRKAPGPQTFIPVEAETQDELIVNISETLQRWTDDKLPAGLHRVSTPKELEERIKTD
                     SSVEIPRRYSIAYLCKADRHASVGTLPAFQTEEKPHYQEMTAAEYHRQRLLTAY"
     mRNA            complement(23864..24873)
                     /locus_tag="MYCTH_2303701"
                     /product="hypothetical protein"
     gene            complement(23864..24873)
                     /locus_tag="MYCTH_2303701"
     CDS             complement(23892..24635)
                     /codon_start=1
                     /db_xref="InterPro:IPR004455"
                     /db_xref="JGIDB:Spoth2_2303701"
                     /locus_tag="MYCTH_2303701"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="AEO57484.1"
                     /transl_table=1
                     /translation="MQSLSETVLTDDVGDRACSVEFVVGDNVGAARRADVVILSCHPHQ
                     GAEVLGMPGMREALSGKLLVSMLGGVSVAKLEEGLYGNPRRSESPGLRPCHILQAIPNV
                     AAARQKSVTVVGGQSASIPGEVLELGHEVLRRIGTPVPVSTNQMPAATALCASGTAFFS
                     WFLEAMVDAAVAQGIERSKATHLAALTMAGAAELVVSGQDPAAVTARVTTPGGATARGL
                     ATLERGEAKETVVKALQATTSKICS"
     mRNA            join(25341..26709,26781..27086)
                     /locus_tag="MYCTH_2303702"
                     /product="hypothetical protein"
     gene            25341..27086
                     /locus_tag="MYCTH_2303702"
     CDS             join(25563..26709,26781..26869)
                     /codon_start=1
                     /db_xref="JGIDB:Spoth2_2303702"
                     /locus_tag="MYCTH_2303702"
                     /product="Diels-Alderase"
                     /protein_id="AEO57485.1"
                     /transl_table=1
                     /translation="MARINRQTAYQKADEIEFSTSSADPLAAWRISGIKGPVWEQWYFD
                     SVADDGKSSVVLTIARDASYALLGRGTLRVELDVTFDDGSHYNNVDWISEAIVEDRSGP
                     KNTGTVDGSWTAPNKAYRYQIAADGSAAKVEIATPEVQGHFTLAALSPPLYPEGETQEE
                     LKASGKTATTELLPKIHLVQVMPTATFEADLVVRDRLVRFRGIGGHMHAWAAGSWFDTT
                     LGWRVTRGVAGPYSVTLMEYTDMDGVVHSSGFVARDGKKLFGAKEVYATPRSSSALQRA
                     LRYTGAGKDERKPKHTVRWTPTYNTGFAGRFGDSSTGAILRFAAAEGEEYQFELVHRRK
                     AFEYLFGSSDTGLTAFLGEIKGGKVGEEVYRGVQFSDVCVLPQGITKVYFFICMLIAVL
                     TFGYINILETNT"
     mRNA            join(27845..27995,28067..28121,28220..28369,28441..29005,
                     29089..29117,29196..29288,29362..29605)
                     /locus_tag="MYCTH_2138881"
                     /product="hypothetical protein"
     gene            27845..29605
                     /locus_tag="MYCTH_2138881"
     CDS             join(27911..27995,28067..28121,28220..28369,28441..29005,
                     29089..29117,29196..29288,29362..29497)
                     /NRPS_PKS="Domain: PKS_ER (25-283). E-value: 1.3e-14.
                     Score: 45.8. Matches aSDomain:
                     nrpspksdomains_MYCTH_2138881_PKS_ER.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="JGIDB:Spoth2_2138881"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 275.7; E-value:
                     7.7e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_2138881"
                     /product="hypothetical protein"
                     /protein_id="AEO57486.1"
                     /sec_met_domain="ADH_N (E-value: 3.1e-31, bitscore: 97.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-17, bitscore:
                     54.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MERIPDTMTAVVFDGPHNISVQQRPTPKIQDDGDIIVKVQAAGLC
                     GSDLHLLRGLEKTKTTGFIMGHEFSGTVVAAGSGVKTVSVGDKIVSPFTVSCGACFYCK
                     NGFSSRCVHCLVFGTEGLAGAQAQFVRVPRADGTVMKAPPEISDDALVLMADVFPTGFF
                     GAKNAFAGLPRTQRPSDAVAVVIGCGPVGLSAIVSALEYKPRHLFAIDAVESRLRVAKY
                     LGAEPLNVADGQENIVKRIGELTEGRGADVVVEAVGLSPALRTAYDIVRPFGSISSIGV
                     HNSSMPFTATEGYDKNVKIQMGRCPVRSIFPEALPVLAKAQHRFGFMFEKLVPLSEAVE
                     SYALFSEMQVQKVIFKPWQRFERENRNTRL"
     aSDomain        join(27986..27995,28067..28121,28220..28369,28441..28999)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_2138881_PKS_ER.1"
                     /evalue="1.30E-14"
                     /label="MYCTH_2138881_PKS_ER.1"
                     /locus_tag="MYCTH_2138881"
                     /protein_end="283"
                     /protein_start="25"
                     /score="45.8"
                     /tool="antismash"
                     /translation="TPKIQDDGDIIVKVQAAGLCGSDLHLLRGLEKTKTTGFIMGHEFS
                     GTVVAAGSGVKTVSVGDKIVSPFTVSCGACFYCKNGFSSRCVHCLVFGTEGLAGAQAQF
                     VRVPRADGTVMKAPPEISDDALVLMADVFPTGFFGAKNAFAGLPRTQRPSDAVAVVIGC
                     GPVGLSAIVSALEYKPRHLFAIDAVESRLRVAKYLGAEPLNVADGQENIVKRIGELTEG
                     RGADVVVEAVGLSPALRTAYDIVRPFGSISSIGVHN"
     CDS_motif       28272..28310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MYCTH_2138881_0001"
                     /evalue="2.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="MYCTH_2138881"
                     /protein_end="77"
                     /protein_start="64"
                     /score="10.6"
                     /tool="antismash"
                     /translation="MGHEFSGTVVAAG"
     mRNA            complement(join(29834..30749,30820..31157))
                     /locus_tag="MYCTH_2303707"
                     /product="hypothetical protein"
     gene            complement(29834..31157)
                     /locus_tag="MYCTH_2303707"
     CDS             complement(join(29929..30749,30820..31042))
                     /codon_start=1
                     /db_xref="JGIDB:Spoth2_2303707"
                     /locus_tag="MYCTH_2303707"
                     /product="short chain dehydrogenase/reductase (SDR)"
                     /protein_id="AEO57487.1"
                     /transl_table=1
                     /translation="MTKIFATGVTGYLGGDAVYAILQAHPEYEISCLVRDKAKGALVSE
                     AHPSLRIVYGSLDDGDLLEEEAANTDIVCNFAHATHEPSVQALARGLARRTRPGPGFLI
                     HTMGSGTVIYDDVVKGRYGQGSDKVFNDLEGLAEVLSVPDFAKARGAENAVRQVGIQLP
                     NQVKTAVVSTGSAYGLGRGILKYRPTAIHELVRATLERKRAIVVGEGKSAWTNVHVHDL
                     SELYLKLVEHAAAGGEETGSGPAVWGGSEGFYFAEGGEHVWSELARSVSAEAAAQGFLT
                     QVEEPESIEPTEASKIMPMGQFFWGCNARVEGRRARQALNWQPHHPSLKEELGSIIATE
                     AKKLGLV"
     mRNA            join(<31614..32196,32323..>33350)
                     /locus_tag="MYCTH_81364"
                     /product="cytochrome P450-like protein"
     gene            <31614..>33350
                     /locus_tag="MYCTH_81364"
     CDS             join(31614..32196,32323..33350)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="JGIDB:Spoth2_81364"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 317.9; E-value: 2e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_81364"
                     /note="Cytochrome P450-like protein; GO_function: GO:4497;
                     iron ion binding - monooxygenase activity [Evidence 20037]
                     [PMID 5506]"
                     /product="p450"
                     /protein_id="AEO57488.1"
                     /sec_met_domain="p450 (E-value: 2.9e-57, bitscore: 184.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTTFSIFGLERPAVLALSIAVGASYVIYLVTITIHRLFFHRISHI
                     PGPKLAALTYYYQSYYDFFPHQGQFIFKLDELHRKYGPIVRIGPDEVHVNDAKFYKEMY
                     GSSTHKRNKSPIWYWMHGLGAVGDQSMFITLDHDHHRLRKAGLGTYFSKRKVQELEPRV
                     KEKVLLLRQRLLERAGGAPVNLKDAFGAMALDIITQYCFNRCFGALDRPDLGREMNKLM
                     GVGVKINPFARTFPTLARTVIKLPRWALKWSGLVSTTAEFLDLADRLSAEARNEAIRDL
                     ASGKYSQTDDADSRTVLHSMMRSDVLPEHEKTEKRLQADGMTLIAAGFDTTSRTLTVIF
                     YHLLTKDHIRARVLDEIRTLMPTPTSPLPTVAQLEQLRYLTCVIHEGTRLAHGVAGRLV
                     RIAPEEDLEYYSPFDGRRYTIPRGTTFGQSSYLVHTDESIYPNPAEFDPDRYWTDDGRP
                     TDAQRYLVPFGKGTRMCVGINLAWAELYLTIAALIGTVDMRIAPGTTEHDVTMVQDLFV
                     GVLPENPGVRVNVVGHLQA"
     mRNA            complement(34117..36040)
                     /locus_tag="MYCTH_2303709"
                     /product="hypothetical protein"
     gene            complement(34117..36040)
                     /locus_tag="MYCTH_2303709"
     CDS             complement(34401..35867)
                     /codon_start=1
                     /db_xref="JGIDB:Spoth2_2303709"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_2303709"
                     /product="hydrolase"
                     /protein_id="AEO57489.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-12, bitscore:
                     37.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MYPFFTYSPNRHYFEYKWYNLELLRLLGAAPYGGCDAAEFLELVA
                     SLIPNDADDWNRKFLALAERTQSWAEEMQRNGHLSAARGAFLRASNYFRCAQYLFPIMP
                     AEEQPYFLSLYHRSISNFEQATKLMEHDVRRVRIPFQPPEYRAPLLRLPGWLHLPAPSR
                     RLKGRKTPVLICIGGADSTQEELYFLHVAEGPGLGYAVLTFDGPGQGLVLREDGVPLRP
                     DGEIVVEAVLDFLASYAEEHPEADLDLDAVAVTGQSLGGYLALRGAADARIKACVAVDP
                     VYDFYDLAMSRMPRWFMWPWERNYMGDGFVDFAVREHAKLDVATKYTFAQGCHMFGSSN
                     PAQMIRDMKQYTFRLDRTVTADNKNRGRANRDYLEWVRCPVLVTGAGGDPKLFLAEMST
                     SAIMRNLVNVPEGQKELWVPKAWSEGGAQAKSGAWPLLQYRTFKFLDEKLGIQRPSSPK
                     RVYENGYENGYTNGFVKNGYENGFVTNGYH"
     mRNA            join(<36984..37402,37490..37695,37771..38672,38734..>38964)
                     /locus_tag="MYCTH_50920"
                     /note="Has EST support"
                     /product="general substrate transporter"
     gene            <36984..>38964
                     /locus_tag="MYCTH_50920"
     CDS             join(36984..37402,37490..37695,37771..38672,38734..38964)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="JGIDB:Spoth2_50920"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 325.8; E-value:
                     5.6e-99)"
                     /gene_kind="transport"
                     /locus_tag="MYCTH_50920"
                     /product="general substrate transporter"
                     /protein_id="AEO57490.1"
                     /transl_table=1
                     /translation="MSEGAGTGTGSAAESSEAAAKKGDEAGEGDATPPKTSHSLRFWGI
                     VASLAFTALCSSIEGTIITSALPTISAELGGDSSFIWVPNGYFLATMVMLPLMAQAANL
                     FGRRWLTLISVAMFTLGSGICGGANSPAMLIGGRVVQGLGGGGIALMINIVLTDLVPLR
                     ERGKYMAIVQMVSAVGAALGPFLGGLLTERSTWRWVFYINLPIGGTSLVALFFFLRVAT
                     PPGGTWVEKLKRIDFIGNAIFIAATVSVLIGVTWGGAVYPWKSANVIVPLVLGFVGIGL
                     FLAYEWTLAKNPSLPRGAIVERTAATVLAVTFLTTLCTYWAFYFMPIYFQGVKAKSAFW
                     SGVDALPLFAGLFPFAIIGGILLSKFGRYKPLHLVGMAIVTVSFGLFSILDRNSSTAAW
                     ACFQLLCAIGSGLMIAILLPAMQAPLDESLVAASTGVWTFVRAFSTVWGVTIPAAIFDN
                     EVAKKAAASLTDQSLVGYLTGGKAYQFATQEFLDSIRDPASRSEVIDIFTSSIKIVWYV
                     GTAFAGLGWLLVWLEKEVTLRSKLNTKFGIEEKKKQEEDEEKAKNEGENKDGEESKAAD
                     GAKRAELSA"
     mRNA            join(<40631..41148,41299..41379,41477..>42023)
                     /locus_tag="MYCTH_48716"
                     /product="alcohol dehydrogenase-like protein"
     gene            <40631..>42023
                     /locus_tag="MYCTH_48716"
     CDS             join(40631..41148,41299..41379,41477..42023)
                     /NRPS_PKS="Domain: PKS_ER (31-242). E-value: 1e-16. Score:
                     52.8. Matches aSDomain:
                     nrpspksdomains_MYCTH_48716_PKS_ER.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="JGIDB:Spoth2_48716"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 158.3; E-value: 4.4e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MYCTH_48716"
                     /note="Alcohol dehydrogenase-like protein"
                     /product="enoylreductase"
                     /protein_id="AEO57491.1"
                     /transl_table=1
                     /translation="MGSLQDLPPLPTTQTAVITTAEGRHAVARDRAVPACGPTSVLVRV
                     RAVALNPTDHKTPARVKTGGLTAGCDFAGEVVAVGARANDEPGDAAACAGIPRRWAPGD
                     RVLGVVYGSNPGAPAWGAFAEYVEADPVMLCRLPDGWDWETAASVGGSVHGSVALCLFG
                     EGKMGLDMGGKKDLQKVVLVYGGSTACGTMALQILRLAGYIPIATCSARNAGLVTAYGA
                     AATFDYNLETCADEIKEYTKSALWYALDCIGTAQSAALCYAALGRAGGRYVALEKYPDS
                     VAALRKVVKPTWVMGPVMFGRDLQLGEGYSQPADPSARAFARIWYPLAEALLGSGALKN
                     HPVKVVAPEGREEWPEAVIRGLGGLRDGKVSAQKLTVTIAA"
     aSDomain        join(40724..41148,41299..41379,41477..41603)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MYCTH_48716_PKS_ER.1"
                     /evalue="1.00E-16"
                     /label="MYCTH_48716_PKS_ER.1"
                     /locus_tag="MYCTH_48716"
                     /protein_end="242"
                     /protein_start="31"
                     /score="52.8"
                     /tool="antismash"
                     /translation="AVPACGPTSVLVRVRAVALNPTDHKTPARVKTGGLTAGCDFAGEV
                     VAVGARANDEPGDAAACAGIPRRWAPGDRVLGVVYGSNPGAPAWGAFAEYVEADPVMLC
                     RLPDGWDWETAASVGGSVHGSVALCLFGEGKMGLDMGGKKDLQKVVLVYGGSTACGTMA
                     LQILRLAGYIPIATCSARNAGLVTAYGAAATFDYNLETCADEIKEYTK"
ORIGIN
        1 agtccacttt gattgctcgc acgtgttaag taccgcaaga gggcaacacc tctcatgtac
       61 tcgtcgatgt cgttgtcgga agtggaatcg aagtccttga aacaaggtca cgatgcaacc
      121 cgtgctcgct ccgcgctttc tccctatgtc caacctgagc cgtgccattg ctccgctcac
      181 aatagagcga aagcgcggct tggttggatg gggacatact ccgatcctca gcttaccatg
      241 ttctaggcag ctcacccatc tggttctagc tcggcatttc ctcaaaagag gaggcggcga
      301 ggaaacctca tccgacggcc actccgtttt acccgctgct gggcgacaag atgacatgga
      361 acctcaagtt caagctctta ctaggggtag gcaagcattt ttgaaccggc ttccccggtt
      421 gtactacaga aatcagataa ttaagcctta tgcgttcacc gaaatgtcga cgactttgtt
      481 gttgctcgtg gcaaatggga ggggagcctt ggaaagcgga cggtgcagag aggtggcagc
      541 agtccaaaac gatgaaccag agataaaatc tgcgatacgt gctgggtatt attattacaa
      601 gtggcaagct ccagtaatta ctgtgtgcac gggcgactag agagcaccag cactgcgtat
      661 ggagtgtaga cagcaagcca taattatgac taattaggat tcaagaaaag catttctaga
      721 ttgcccgaga acctcgataa gaacctatcg acgctaggaa aatacatgtg ttacgccgct
      781 ctctagtcag gcatgcttaa atatcctccg attagttagc gcaagaagat ttgtatgtat
      841 cccaaagtgg attggtaata tcttctcatc cgaggtactt aggtggaccc ctgagtgttc
      901 agtcttcatc cagatcatca tcgccgtcat gcttgtccgc ggcaacgcga acaatctgac
      961 attcggcccc gtcaagatca accccagtct cgacatctat taaatcccag tactcgggca
     1021 actcgggatc ctcatccttc aaccccgcca gctcggcttc gaatgattca acctgcccct
     1081 cctcctcctc ctcctcctcc tcctcctcct cctcctccct cttaataatc ctgaccttcc
     1141 tctccccatc ggcatacaaa tccccttcga tcctgggccg cctctgcccc gtgaccttct
     1201 tcctcctgta cagcacctcg cgcaggctat aggccagcac gaacggcccc tcgatcctac
     1261 ccgccgaccg gccctccatc gcctccgtcg cctcggcgcc caccccggca ccgaccggta
     1321 ccccgccggc agcggtggtg atcagatccg tgaggaagtg caggcggacc ccgcgcgcgc
     1381 gcgcgcccga caccaggtac tcggcgccgt gggtggcgat ctgcagcccc gtgacgaggt
     1441 acaggttggc ggtgaagcgg ctgtcgcgga gggcggcctg gacggcgggc tcggcgaaga
     1501 gggcggcgac gtcggccgcg gacgggtgga tcgtgcgggt ctcgaggcgc gggatccggt
     1561 aggcggcgcc gcccgccgtc gagtacgcca cgctgagctc gacggggttc tggccgagga
     1621 ggcccgagag gaaggagagg aagacggtcg gctggaggga gcgcgcggcg tgggccgacc
     1681 gggtcgcgtc cgcttccggg acgacggtcg cggcggactg gaggcgccgg acggtcggag
     1741 agttggggtc gttgagcggg aagtcgggct cgcgagggga cctgatcagg ttcccgagcg
     1801 cgatgggccc cgtcggagcc tgatcgcgcg ttggagcgag gaagtaggtt ctcttgggat
     1861 gcatctttca ggttttgagg tggtgtaggg gaagctacat taaggataat cataagagga
     1921 atgaggttgt aaagtaccta gcacccgtgt attattcttt ttttttgttg tatttatttc
     1981 tattaattag tagaatgttt aagagaacgt ggaggcatcc gaaccccgct ttcgagggac
     2041 cttgtagaaa ccttcaaatc tgcaaacaga aaccttcaaa ttgctgctgg cctaaatgtt
     2101 aatatcaatg tatgacaact acactaatta ccttaggtat atactgtagc aaagtacggt
     2161 aaggtaaccc ttacgatggt gttgtgataa gtagtcaaca ttgaagagaa tttcagtttc
     2221 tatttggagc gtactcggtc gtagtattat gtcagacatt gagggttcac gaattggttt
     2281 cacgttaatt atgtcagaag catattgtgt atctatctaa cgcttcactc gagcgaccta
     2341 caagcaacca taattataac gagacatgct tgctaaacgc attggccatt tcgtatgtct
     2401 atatatctac ctatatagcg ctcgtttcct tctttcccta ggtaccttac caagtttaca
     2461 cgggcatttt gttgaacttt cgaagccacc gctagagagt ctctttcttc tgacccttct
     2521 attgttcgag tcttccgact gcgttctaga catcatgata cgacccagag ctgcttacgg
     2581 taagtagtcc aagttaaggc acctaagttg ttgtgtgctt atgaataaag gaactcatca
     2641 aaagcccatt agctgtcact gcacagcccc actgaggccg cccgcacccg tttacatagc
     2701 caccgtaata tctatatacc gtttgcctag gcggttcagg gtctgatgtg taaacactcg
     2761 gccgttgcac tcttcatatt ctcagtcctg tccccggtgc tatcgcatga tgagccattg
     2821 aatttgtaga aggaagctct ggcggtgaaa acaacgtatg tactactgtg taagtacgaa
     2881 gcgcgccgct gaacccagga gcgggttatc cacccttttc ttggacgttg gccactggcc
     2941 tcgcctgatg tgttggtcgg ttatgcggcc cgccgtacgg cccgcttggg ctgcctggtg
     3001 gaggtggacc tcggcttcct gagccaccaa ttgcggcggg gcccccctcc tagtggtcca
     3061 ctgaggcgag ggcgcctgcc tccgttgccg ctggactccg agactagtta ccgaagacat
     3121 gcactcggaa ctacgggttg agctatttgt gctcctcgtt ggaaacgggg aattcagaat
     3181 atccgacgtt tggttggttg ccacgctcac caacctgcag atcagccagg aaatgatggc
     3241 ggtgacgaca agatgtgtga gttaggggca gcggcgacgt cgtttgctgt cgcccgacgc
     3301 gggggtgagt ggtcgccatc gacgccggct cggccaaaca gagcaggaag tccaaaggca
     3361 ccacagaggg gagtgccaag tgcacgagag cttcgtgcat tgcgtgtctt gaaactcgac
     3421 gggaagattc caaagggaat gtactcccag ccccggaagt caaggtcaac atggcgacat
     3481 caacacgcca gcgcttgaac gatccctcgt cgctatggca aggcgagggc tcaggtagga
     3541 ggggtcaatc ccacaggccc ctcaagaagg agtatctcgc ttagaatacc tcttcgagct
     3601 gaatcagctc gcccacccct gctcgataac aacgaaccaa ccacaaacgc taccgcgcgg
     3661 ctacgcacag ctgggacgtc caacatgtat gaatgtacgg atgtatgtac ggatgtatgt
     3721 acatacgaag tatatatcat atgggggtta ctacccaaaa tcttcgagcc ctaccgacat
     3781 ctgcttaaca ttcaggagta cccagttacc gacagtatca ttagctgaga gacatcggat
     3841 atcccgctac tcacttcccc tcgttggcca gataatacct tggaaaaggc cgtgaagccc
     3901 gaggctgctg acggtgtttc tcctcacctc cgtcttatcg gcatacgacc aaaggtccga
     3961 cattgaaacc ccctggcgtc gagaggagac cgacaattgc catgttgcag attagaaagg
     4021 ctcagacggt tccgatcccg gtgggacgca gcgagagacg ccaaatagaa gcactgccca
     4081 cgttcgctcc tggcacgcta atctttctca atcatgaccc cgcgagcgaa ggacgtctgt
     4141 cagcgtctgc aacaagtctt gttgttcagg aaacacgtgc ccgttctagc tcaacaggca
     4201 gggcacttcc cgaatcggct tctctcaggg aaccttacga caaagaacac cgcgagagcc
     4261 gttcgagccc tcccaccaag tcaagcgacc gggatctggc ctccgaatcg acccccagcg
     4321 aagacactct cggcgaacaa cgtagtaaga cgctggaaga gtcagggccg aaacccgtac
     4381 tggtaaacgc gagaaaacaa gacacagagg agttgggatc cggggtggat aacccgatat
     4441 tgataccttc gggcgtaaac ccgggcccgc ccaaggagtc agagccgaaa tcatcagtag
     4501 ttaataaggg ttccatctcg gatgcaactc aacagctcgt agacgataca aggtatgtaa
     4561 gtacatacaa ctcgttcagg ttttcatcca ataaagacga atagacctga atcactaact
     4621 atcaactgct agtgtggata tctggtttgg cgacatcgaa aaaatcaatg aagagatcct
     4681 cgaaccctac agacgacagg cctgcaagag ggtcaaagta ggcatcctgg acacgggcat
     4741 tgacatgaag aacacggcat ttcacaaagc ggaggtccgg cagcgcatta agaagcgcgt
     4801 cgatttctgc gaccctaacg gcaaaggaac tgggagagac aagtgcggcc atggcacgca
     4861 ttgcgccgct ctcataaacc gaatcgcccc tgcagccgat atttacgtcg ggcgggtggc
     4921 gattgacttt gactcgggtg tggatgagaa cgtcgtagca aaggtaataa gccagagaga
     4981 gaattgtcag ccatgtccca tggagcttaa gtaattattg ggccttaatg tgctgactat
     5041 tagtacctta atatgtcatt ccccaacagg ccatcactat cgctcttggc tccaggggcc
     5101 ctggcgacgc ctccaacaac tgggacgtcg acatcctctc cctctcgctt ggtttccagc
     5161 actatagcga ggctatcgac acagctctcc gaacgtcgac ccgcaagggc aagatcgttc
     5221 tcgccgctgc atccaacaac ggcaccctgc gtgccatggc ctacccggcc tgggatcccg
     5281 acgtcatccc catcaactcg gccaacgcga ggggccgacc atccgacttc aacccgcccg
     5341 cggtgccggg caggacgctg acaatcttgg gcgagaatgt gccctcggcc tggatcacaa
     5401 ctactccgac ggcgacgaca accgcatcga cgacagacat gagcggtcca gacgacgccg
     5461 gcgctccaga agctgcagcg gcggcagtag acctcgcggc aacgaggcgc atgtcgggta
     5521 cctcggtggc gacgccgatt gccgccggcc tcgtggcact tctgtttgag ttcgccatgg
     5581 tcgaggtgcc aaacgacccg gtgacccagg cgacgctcaa tgacgtgctc cccaatatca
     5641 agcgccagac gggtctgaat gcgctgctga tgggcaaggc cgcgaggaca ggtgatttcc
     5701 acaacattgt gccgatgaac ctcctcaacc cgaacctgac attgggcgaa aacgccgccg
     5761 tgatcaaagg ggtcttagca agatggttcg ggtttagacg ccccatcaaa ggaactgacg
     5821 gcgtatagga taaggtgagc caacatgact acagtcgcca ttcatcgtga gtgcctgcac
     5881 agccctgggc atgaaactgt gctgcttaca atatcaaatt acagtgcagt tggtgattgc
     5941 gacagaggcg aacgtcccat tcccccagta ccttagtcag tcagtttctt ggctgataga
     6001 attgtgatga aacacaagga ttggataaag ataggattct acattcccac agggggggca
     6061 taacaaacta ggagactcag gggtaatcaa gactcaaagc gcttgttccc ttgtctcaca
     6121 tcagccaacc ctaaatcgtc tcgagaagag ttacacgagg acatcgtagc cactgggatt
     6181 gaactggtca ggaaatatcc aaaaagagaa taacgttaag cacagtatct ttattatcta
     6241 tgtaggtcat catcctgcaa aaaacattgt tggtaaacca taactaacaa gacaaaaatc
     6301 ccttgcatat atacagacac ccaatacagc atagcaaaaa ccaaaatgcc ttatgtacac
     6361 ccatgaaaag ccagccagac tctgagaaag gaagcacaca tgcataccta caaatgaaaa
     6421 agtcaagttt ccccactacc attccacacc ttaagttcct ccacattaac ccaggccatt
     6481 cgccattcag ggcctcgggc cgttcaacgc cttaggaaac ctccacttct ggcccttcct
     6541 atcagtcaga ttcaccccct tcatgtactc gaccacctcg tccggcatgc ccgccgcctt
     6601 ggcctcggca atccactcgg cgtcgggcgt gaccgtgacg gtcctgcgga gctgcttggt
     6661 gaggtacggc gccaggccgt gcacgtcgac cgtgtcctcc gggcggccgt tgtggtttcg
     6721 gtactgcacc agctggccgg acgattgttg cggcgtagta gtagtagtag tagtggtagt
     6781 agtggtggta gcgcccgaag agagcacggc cgagaggatg ccgcccgcga cgtcctcgac
     6841 ggggacgaac tggaaggtgc cctcgagcgc cgacatggac gggacggtgg ccatctggcg
     6901 cgagtagtgc aggatgttgg acatgacgtc caggtgcggc gcgttctccc cgacgatggc
     6961 cgtgggccgg tggatggtga cggggagccc cgtcacggcg ctggcgcgct ccaggtacag
     7021 ctcgctggcc cacttggaga gcacgtagcc ctccggggag ctggtgggcg ggaaggcgcc
     7081 gagagactcc tcgtagaggt cgtggccgag catcgtggcg atgccggcgg tcgagatgta
     7141 gtgcaggtgg cggacgttgc cgtgctggag cgcgagcttg acaatgtcct tggtcgactc
     7201 gaggttggtg cggcggacgc tgccgtaggc cttgaggaag gacacgtcgg cgccgttgtg
     7261 gatgacggcg tgcgatgttt tgaagacctc ggtcgcggcg gtgtcggtca ggcccagttg
     7321 aggctttgac aggtcgccag ggtgaatgac cagcttcggg gacgaaactt gggccagctt
     7381 gctctgacta cgaaccgcca gcgcatggac cgtcttgacc tccggcagcc gcacgagctg
     7441 ccgaacaagt tcaagtccga ggaacccgga agcaccggtc agagcgatga cgaggccgct
     7501 cttgggcatc ggcgacgcgg gagcgcgcag gtgggacaat gcaggctgta gcttgatctc
     7561 acggggccag tcgatgccag aagttgccga cgcgttgttg cggtcctttc cgtccagcag
     7621 cgaagccatc tgcgccagcg tgttgcgctg gaaaagctga gtaaggggca catccaggcc
     7681 gtactgcttt ctgaggtcgc cttgcacacg gatcagcagc agagagttac caccgacgag
     7741 gaagaagtca gagttcgggc cgagggtgtg tgcgtgtacc gactccccca ggacattgag
     7801 ccataggtct ttcatcttgt tcaggttctc gttgccgccg aggtcgacgg cggccgccgc
     7861 cccaaccggt gtttctgtcg ctttcccgag cgccctggtt agcggcaatt tagctaccgc
     7921 cttcctgtca accttgccat ggtgggtgag cggcagggaa gtaacggcca caatcacagc
     7981 cggccgcatg tagtccggta cgcgaagctc cgcaactacc ttgtcaagga aggtctcttg
     8041 ctcggcggga gtggcgtagc gcgcccgtcc ttcctcgctc agaacaacgt gcgccgccag
     8101 gaagtcagcg ctcgagttat tcggctccgg cttgcgcacg tgaacgaccg cgtcgctgac
     8161 gagccccttg gctgtcgaca ggagctgtgc ctcaatgtcc agcatgtcga tgcgcagacc
     8221 acgaagcttg acctgggtgt cgccattgat ccgcgcctgg aggatgaact ggccgtcaga
     8281 ttcacgaagg tagccgctgt cgccgctgtg atggaccagc ttccagcctt gcttcacaaa
     8341 ttctgccggg gcgagatcgt cctcggggaa tctctcggca gtcagctcag ggttaccaac
     8401 atagccatcg gcaattccag ctccggcaaa gagcagctgg ccagggatac cggcaggaac
     8461 cggatggcct tgtgcgtcaa caacccgggc ggtgtagttg ggcatgaccc gaccgatagg
     8521 aacgggcatg tcgctagcag aaaagctgcg atacaagacc tcgtaggcgt tgggtatcat
     8581 ggtttcagtt gggccgtaga tgttgatggc gcgcaagtca ggcttgtcca gaagcctgag
     8641 atggttgatg aggttctgac tgtacggctc gcccccagag caatgccatg tccacgcaga
     8701 cgaccgcagc gcagccaggt caccgccctg gagccaagca acggactcgc tcgggactgc
     8761 gaatgtaaaa gtgaccttct tcgagacgat caggtcggtc aacgcccgtg gatccctgcg
     8821 agcttctggc ccagcaacga ccactgtacc cttggtggca agggcgataa tggcacccca
     8881 ccaagagaca tcgaagctga gaggagtctg ttgaagaacc gtctgtggcg acatgggcca
     8941 acgatggagg aaactgcgag ccgcgttcac cacaacgcga tgggcaatcg aaataccctg
     9001 aaacggcgtg gtatcattaa ttagcagacg cggtgcggtg tcatcacagc taattaatgg
     9061 ccaacatacc ttgggaacac cagtcgaccc actggtgtag atgatcatag cttcatcact
     9121 tggcttgtgg ttcgaaacga aagaggttgc ggcgaggcgg ttgaacggca gcgtggacac
     9181 gttgatcacc ttgactgtgt cgtcgagagc caactgcgaa acgagcggca cggtggggtc
     9241 atggaccagg acagcagcca gctttgcctc ttttgcgacg tcggcaagac ggcgcacacc
     9301 ctgggtggtt tccaggggga cgtatgtttt ctccgcccgc cagacaccga gcatggagca
     9361 gacccagtca acgtcaggct cttggaacac tccaatcctg gaacgagcgg gtagtcctag
     9421 gtttactagg ctttggccga tggcaacgga tctcaacttg aggtcagacc aagaaagcga
     9481 gtttccttgg ctatctcgta gagcaaccgc accgggctgc tgcgctgcag tctcgtctac
     9541 ctcggtcaag atggtcgggt gctgaaggtc aagaaattcg cctatcaagg aatcagcgtc
     9601 gatgatccga gcctcctaac caaaatcgac aaaactcacc cttgccaagt tgcaaagccc
     9661 tgttcacttc gccggcgtcg aacatctgag gctgccctgc agccagttcg gtgtccttag
     9721 tgaatgcatc caagagagtc gtgtaacatc ccatgatggt ctgcgactcc tccggtgtgt
     9781 agagggcctc ctgggtgagt agcttcaacg aggcttctcc ggtgggggta tcaatcatct
     9841 caatcatgac atcgtacggc gtcttgctga cgatgtatcg cttgccttcc agatgacctt
     9901 ttccgaacgg cagcttctcc gtgacatagc gatagtcgat gaaggcctgg aagagggggc
     9961 tgtgggtcga acttcgttgc accccgacct tctccatgat gacatcgaag ggcaccgccg
    10021 agttggccaa gccatgcagg accttgttct tggtcgcctt gaccaacgag gagaatggca
    10081 ggttgagatc agttggcaac ctcaggggaa tcaggttgag gaagtttcca atgctgtctg
    10141 tcgcgccgac atcagcgcgg ttcgcgtcgg cgataccgat gcaaatgtca tcggtggcag
    10201 ccagacgagc cagggtgatt tgcagaatcg tcgtgtagat gtggaaaggc gtgaccttga
    10261 gcttgcggca ggccgacttg acttgacggg caaccgaggc cgacactctc gtctcaatac
    10321 tccggttttc gtacgttgtc aggttagggc gcggccgaga ggtattcgga gacacgttga
    10381 gaatggggag cggatctgga agtctcgcaa actcgttcga ccagtaggcg atcagagaat
    10441 cccaattgcc cttgctgagt tgttcaactt gatacttgga aaagtccgag tactgcatcc
    10501 gcggaggcga gagtttttgg cccgcgtaga tcttgatcat gtccgcgaca aagacgacaa
    10561 aactcgacga gtccatgttg atgtggtggt atccgacgag caaatgatgg tgtgttcgcg
    10621 aagtcgagac caacatggcc ctcatggtct cgcccttgct caggtcatag acggtattgt
    10681 gcacctcctg gaagagccga tcgatgtcgg agacggaagc actcacggtc tccaaacgca
    10741 aggggctttc cttcaaaatg gcttgcatcg gctgatcgtc ttcgtggaaa aagcacgtcc
    10801 tcagcgcctc gtggcgggct ccaaccatct ccactgcgcg gctcagggcc cgtacgtcga
    10861 tttccgactg gatctcgaca tcgcaagaga tattgaacgc ggttgggtcc tggacaattt
    10921 gcgtcatgac ccagaaccga gattgaccaa aggacatcgg cagcaccttc tcaatggcgg
    10981 ggctctggga gattgtcagt gatggcgaca gtgagactgg ttgcgaagag ggcggcgcaa
    11041 ccagactagt actctcggtt gggtctgcaa cagaagaggc aggtgatgac gacccagtcg
    11101 gcgtcggtgc ctcggtttca cttgcgctag acggcacgga aggaagggtg ggactgccat
    11161 tcggcttggt ggtggtggcc accggcggcg cggcaggggg aactgaagcg gcgacaggct
    11221 tgggatgctc ctcctttgcc tttggtgccg taaggctctc ttccgtgatg gcgtccttgc
    11281 cgttcgggtc caggttaggc acgtattcgg caggaaggtt ttcgacagca tagtcaacga
    11341 gcccctggac gggtgtgtcg gagagaatct tcaggactgg aatgtcgact ccaagttcac
    11401 tacgcatcca cgtgcgcagc tcaaccgcaa gaagggagtc gaggccgagg gcgctcgtgc
    11461 cctgctggag gagggcgtcg gggttgttga caagttcgtc gctgagactc aagatgttct
    11521 gaagcttgtt caaaacggca actgggaggt ggttatacat ggttagtgtt tggggggggt
    11581 ctctccaaat gcgctggctg acttgacact cacctcgaag aaccctgccg acgtcgcccg
    11641 gcgatcttgc tctcttcagg aggtcctcca gcgactccac ttgagctgag ccttccgagg
    11701 aggcgcccga ggctccgtca gtgttgagta gcaggtgcga gaatctggcg ttgtcgaccc
    11761 aggtgggttg gaatttgccc ttcttggggt gcacggtcag gcccgtgatg agctcctcgg
    11821 gctctcgaga atcgacccgg cccatcaaaa tgccgttggt gaatgttgct aggaagtctc
    11881 tcccggacat cttgcggtat ccgtggctga ccaggaggtt catgacgttc tcggagacat
    11941 cgcgagccat aagtccgaca cctgcaatag ggccgatgtc gatgacactt gcattgagac
    12001 cacgagcgcg gcgctgcgat gccaagccga gcatgtagat gttggccgtg tcgtaattgc
    12061 tctggccggc ccgccccagg acgatggaga tggacgagaa gccgatgaaa aagtcgagcg
    12121 ggtcatcgta gaagatctgg tcaaggatgc gtgtgccttc gaccttgggt ctcagcacct
    12181 tgttcatgtc atcgaaagtc atgtcttcga aagacatgtc gttcagaacg ttggcgccgt
    12241 ttgccacacc ggcgattggc ggccaagaag accgcaggtc tgcgataagg ctccggacat
    12301 cgttctcatc ggtaatgtcg ctatttttca aaatgattaa tttaatcggg accgctctgt
    12361 tgatagggaa actctaatta ggcagtggtg gacttacttt ttaacggcct tgatctggac
    12421 acccttagct gcgtattcgg cgatcagatg cgggtcgaca ctaggtctcc ggctggtgag
    12481 gacgatgtat cgggcgccga ggctgaccat gtactcggcc aacggcagtc cgaggccacc
    12541 ggctccagcg aggccgaaca agacataagt acggtctccc ctgaagattg gaagggcgtc
    12601 tgatggcttc accgagaccg agaccgagct gctggccgtc cagtcgatca cggaagcggc
    12661 gcttgactga ggatcggcga cgtatgcatc ggcagacacc gcgccgctct tggagaggtt
    12721 tgtcggtgcc aagtgcactg cttcctggca gagcgcagcg agggcagtgg tgctgaagtt
    12781 gcgagcttgg aaggaactgg ccttctcaaa cctcgcagca tcgggtaaga gggctttgat
    12841 ttgggccaca aagttgccgc gccaagagga tggcttggtg aagtcgatga cggaggcgat
    12901 gcgcggtggc aaggcacgac ggattgtgcg gctgctggca tgagcgctga cggagacgcc
    12961 cggataggcg cgcttgcttg ccgggcttgt cgtcaccgag gtaacgctaa gcctcttctc
    13021 tccggccaac ttggccacgg actcggccag gtcatcgtcg ggatcgacaa ggagggtagt
    13081 tccgtccacg gtggcggcct cgctgcagat cagtgatgcg aggagatggg aggtgatggc
    13141 ccgcagacgg gagggagcct catccaaggg atagttgtac gggaccacgg acgaagccgg
    13201 gacttcgacg atggaggcga tgctcttggc tagcgcaacc acgggcgcat cggtggcagt
    13261 atcgagaccg atgaagggat acagagcctg cgatgatgac ggcctcagcg ggactgtggc
    13321 cgaatacaga acgcgcactc gcgtgacttc ctccccatcg gtgcggcgag cctcgggtgc
    13381 gagaacgcgg atgagagcgc gattctggct gccgttatta tcatcatggg attcgaccac
    13441 ttcgacaacc tccttggcag ggtctgcttc ggcgacgatc tggcgacgag acgagttgta
    13501 gcggtcgtta gtggcctggt ggggtacgat tctaggcacc cacttgcggc cctctgcatc
    13561 gacctcgaat tccggttctt tcacccaaac aaagtcggca ctctcgcggg ccaaccgccc
    13621 cagaatctgc aaccggagca attcgtcaac caacatgtgg gcatcgagcc gcgcgtcgac
    13681 agcgaagtcg ataaactgca cattgatttt ggcatgggcc tgctcgacca tcattgcacg
    13741 accgagaccc agcgacatga tggcgtgcgg gttatcgcgc cgcgcgccgc gcgttgccca
    13801 aagcaccgtt tgagcagtgg tccagagctt cttcaatccg tcgtgcgctt cgggagtgta
    13861 tctcgtgaac acgggttcgt caagatctgc gagatacagg acggttggac gagcggacaa
    13921 gtccagactc gccaggtctt gcgccgcggg caccacggtg atgcgctccg agtgcagctc
    13981 gaggaggcgc ctcatcttct cggcaagccg gaccgagacg agcgaccggc cggagacaat
    14041 gactagctcg tcgatgtgcg acaaggcgga ggcatcgttc ttggagctcg gctcgagaag
    14101 gagatcgatg tgctcgttcg tcgcccgcga caccaagacg ctgtatggac ggggcaggac
    14161 atccagctct ggcgtgctag tctcgatgcc gctgaaccca gcctggacca gagcggcgtg
    14221 ccattcggcg gcggacaaac gctttgtcga gccccgtcca cggttcttgg ctggccacca
    14281 gccttccaaa ccacccatca tggcgggcag gcgaacagtc gcgcccgaag tggcttcgag
    14341 aagtgccaga tacccaccgg gcttcagcaa ctggtgtagg ttgctcaggt aggcctcggg
    14401 gtcttggggc caggtgtgta gcgctaacac accaataacc aggtcgtacg agtgtgcttg
    14461 gaagccctgc tccgcgagat ccgcgccaag ctcgagaact tggaaagaca tgcgcccttg
    14521 gtaatccggg aagagactct tggccgcctc aacagcatct ggcgagacgt ccgtgaacgt
    14581 gtaatggctg aatgcgtgcg acgccctctt caggatcttc ttggtcgcgt tcccagaccg
    14641 accacccact tcgaggatac gcacatgagg gttgacgtgc gttatctggc cgactacttc
    14701 tgccaagaag ccggtgtact cgcctagccc aagcgactcc tcgtaccagc ggtccagcag
    14761 gccatccttg gtcatgtgtg ttaggatgtc gccctggcct cgtacagcat ccgccaagtg
    14821 ctcgcccaca ttccgcagga gctgcacgtc gactcggtcg ccgaacgcat ccatcagcgg
    14881 ttccagagtc tcagccgtgt cacggagcca ttctttcttg aagaagcgct gcctaccgcc
    14941 gcgcgcaagt gcgaccgatt gccgcgcgaa ctcgagcagt ttcttatggt gccatcgagc
    15001 ccctgcctcc tcgtctggcc ggatgctctc ggcgaggttg cggaggtaaa agtgggccac
    15061 ccgctccagc aaccagccga gttcgttatc ctcctggctg gctctgttgt cgccagcggc
    15121 gatcgcgcca tcgggagaag cagtgttcca agtgttgaca tagaacatct gcgtatcctg
    15181 ggactcggtg gcaggggcaa agggaatgag acggatgttt tccacctgga tcaagcctgt
    15241 gcggccatca ccagagaata tgtccacgtc gccggagaga tcgatcttgc cgctaaggct
    15301 ctcggccgcg ttgatggccg catcaaagct gaggtaatcg tcagagttgg cacggcaccg
    15361 ggcagcgtcg attcggatgc tcttgatcga cacgggcacg tgaagtgacc agatgcggcc
    15421 atcgcccggg tacgaatacg ccaggaacat tgcctgaaaa gccgcgtcaa ggtatccggg
    15481 gtgaactagc aggtccttct cagatggatg catgctagcg gcgtccacct tcgagatgcg
    15541 cccacgaccg aaatcggact ttcgcgtcat cgagtgcaga gctcggaaag cgcccgagta
    15601 cccgtatccc agctgcttga gttctgagta gaacagcgag tcgtcgacct cggtcatggc
    15661 tgcggggccc gcctcctggg ccggtagtga ctccagaggc tcagcggcac catcaccggc
    15721 aactgtaact tgcatccggc ctgacgcgtt cagagcggca tcggtcgact cggctgtggc
    15781 cgtcacagaa cgcgcgaaga agcttgtctc gaacacgcgg tggccgtcga tctctgtggc
    15841 cttgtcgatg tgcaatgaga agaccagctc aataccagcc ttgtcgctct cgaacgcgat
    15901 cgccttgccg atgtcaaggt ccttcaactc gatcttggca agtggccctg cggctgctgc
    15961 cttcgcgagc tgcttggccg cctctgctgc cagcgccacg tagccggcgg cagggaagac
    16021 ggtttgcccc tgcagctgat ggccgctgat ccagggcaga ttggaaagtc ggagcacggt
    16081 atgccagctc agatccgtat cgttcgaatc cgggctgagt attccaagca gcggatggcc
    16141 aggctcggtt cgcagacgaa gggctcgtga ccggcgagac tcgttccaga atacccgctt
    16201 gttgtcccag gggtaggtag ggagatcctt gataatcgac ggtctggcac ccgacagccc
    16261 gtgagcggtg atgtggtact tgtccaggtc caacgcgccg tcagccgcgt tggcccagat
    16321 ctggccgatc gcgttggcga aggcttcact gctgtcgctg tttcttgaca ggcagctgat
    16381 ataagccggg actgacttgg taacggcctt catcgtgtcc aacgccggcc ccttcagggt
    16441 gccgtgcggg ccaacctcga tggcgatggt gtactgttcc tcagcacagg cgctctccac
    16501 ggcggtggag aagagcaccg tctgagccat gttgcgtgcc cagtacacac tgtcgagttc
    16561 ttcattcgcg tgaccggtga ggacggcgcc gtcgtgcacc gacgagtacc acttgcagcc
    16621 atccctaggt ttgttggccg tgactcccgc tttccgaaga gacgcaacat aggggtcgct
    16681 gcaaggccgc atgtggtggg agtgatatgc cttgtcgacc cggagggcgc gagcgaattt
    16741 actctcatcc tcaaatacct ccttggcctc ctcgatcgca tcagcgtcgc ccgagagagt
    16801 gacgctggtt ggcgagttgc atgccgcaat gccgatgcgt ccttcgaacc gcggcaacga
    16861 gacaaagtcc tcggcatcct cgggactggt tcccacagcc agcatggcac cacgctgccc
    16921 gtccggaccg ccggcgagtt tcgtgtgaac gccgcggtag tacgcggtca caatggcatc
    16981 gcgggccgag agcaccccgg ctgcgtacgc cgcgccgatc tctccggagc tgtggcccac
    17041 aaccgccgag aacttgacat tggcggcggt cagaaggtcc acgagcagga tttgcagtgc
    17101 cgtgcacaac ggctgggcgt actctgccag gtgcagtttg gacttggagc cctccgccac
    17161 gagctcttcc ctcagtgacc acgagggccg gtcggccgcc gggagcgtcg cgagagccag
    17221 ctcaagctcc tgaatgcggg cctgggcgaa cggagaggcc tcgagaagct gcttgcccat
    17281 acccggccac tgcgctccct ggcccgtgaa gatgcccagg atcttcatgg gccggttcgg
    17341 cgggcggacg actgcctggg tctcccactc gggcgaccca accgagtcaa gcacgcgctt
    17401 tctgagaccc tctacgtccc tagccacata ggccacccgg tacgggaacg tggagcgacg
    17461 ggagttgagg gtgtaggcca ggtcacgggc gctgatgttg ggtgactgcc cgaggaagtc
    17521 ggcggtattc ctcagcgcct ggctcagcga ggccttgctt gctgccgaga aggtgaaggt
    17581 ccacacgcga gcaacgatgc ccatctcggc acgtggtaga gccgtcgggg gctcgtacct
    17641 ctcaaggatg gcgtgagcgt tcgtaccgcc gaagccgaag ctgttgacac tcgcgcgctt
    17701 aggcgctccc tctggccact cgcgcgcttt gacgggtacc tcgaggccct tgtaaaacgg
    17761 ttcgatgcgg gggttaagcg tcttgaacag caggttggga ggaataagac ggttctgcaa
    17821 cgctaaagag gccttcatca ggcccgcgat gcccgcggtg ccttcagtat ggccgatgat
    17881 cgtcttgacc gacccgacgt acaacttctc cccgggtccg agacggctgc cgatggcccg
    17941 gtggattgcc tcggcctcga gaggatctcc cgtggccgtt ccggtgccgt gcgcctcgaa
    18001 gtactgcggc ctgtcagaag gcgagctcaa gtccaggccg gcgcgacggt atgtgtcttc
    18061 gatcagcgcc acttgcgcat ccgggctggg aaccgtgatg ccgcctgtac ggccgtcttg
    18121 gttgacgccc gtctcacgga ttatgcactc gatcggatcg ccatccgcaa tagcatcgct
    18181 gagcttcttc aggaccacgg cggcgacgcc gtccccacgc ccgtatccgt cggcctcagc
    18241 gtcccacatg tgggagcggc cacggggcga gagcatgtgg aaggtgctct ctgagatgta
    18301 gggctcaggg ccgaggagga ggtttgttcc cgcagcgaca gccatccgcg aatgaccagc
    18361 gcggagctgt tgtacgcatt ggtgaacggc gacgagagac gacgagcacg ccgtgtcaat
    18421 cgtcatactc ggtccgtgcc agtcgaagaa ataggagata cggttcgaca cgatagaacg
    18481 ggctgttccg gtcgcgtgat actattcaga gcaagagtca gcatcggcag gcacatgtca
    18541 cttggggaaa gggaggcaat ggcttgtcag acgtacagtc ggcatcatgt ccagctctct
    18601 cccttggatg ctgctgtatt cctctcccat caacccgacg tagacagcgg tgtcgctgcc
    18661 cctgaggtca ccgatcctct gtccggcggc ttcgagagcc tcgtagacgg tctccatcag
    18721 cagcctctgc tgggggtcga ttgccgcggc ctcattggcc gagatgttga agaagtcggc
    18781 atcccacgcg cggacgtcct catcgagcac gtacgagtgc aggacgttgc tgtgaccgct
    18841 ggtgtcaccg acgggattgt agaagccgtg gggatcaaac cgcgagcgag gaatctcaga
    18901 caggacgtcc cgaggcttcg acaagagatc ccagagcttt gatggtgagg atgcgctgcc
    18961 tgggaatcgg cagccggagc cgatgatggc aattggctcg ctctttgcct gagcagaaga
    19021 catttttggt tttttttcgt tgctgtgaga gaagaatatt ctgctcgttc tgttggtggc
    19081 aaaggggaag gaagagaagg atgaagggga ggcaacttca agtggtgcca gtcacatcaa
    19141 ctccaaagtt gactcctaac gatacaagac atggactaca actaataccg gtacgtaggg
    19201 ccgtatatag gtctcgaact cgagtatccc gcaaacccat gcccttttgt taattacccc
    19261 cttcacttgc acaggcgagg gtattcccac ggctcctgta tcggctccgt tcaccgttga
    19321 aaggtgacgg tgccgaagat tggtgccatc gatgcaatac catgagcgac tcctcgatcg
    19381 gactcagccg atgggaaaac gaggcaccgg cgtgggagct tcggcggagt ggatcaccat
    19441 cggagcatgg tgccggcgtg ctttgcttgg aacggcaagt gggtcacccg aacaggaacc
    19501 gggtcttggc catcggctcg gggaccctct ctctctcccc agccacgcgg gtcgatggaa
    19561 ccttaatcgc ttaacgttat ggcgcttaca cagtacgtta ccggtcgctt cctccctcga
    19621 tggattcgac ctgtacggag tacctcaccg aaagtcaccg aaacaaggat ctgcatgcaa
    19681 actgtcaacg ccaaacccgt cttgaccttt cgcagcattt cgcgtccttt cgtggtaatt
    19741 ttttgcttca ttttttgggg gggtcttttt tcttttgcac caagaggaaa cacactgatt
    19801 gaccttcgtg ttgggagcag actcgggatg acaaatagta cttagatagg taccttggtt
    19861 gaatcgcctc attagccggg ggctgaatcc atcaagaagt tctattctga taataattcg
    19921 aatcctgata attgacacga gatagtcctg aaaatggtga tccaaggtga tttgacccct
    19981 cgtatcccga agcctgcgac agacagggtc acgatgagaa ctaacgaccg ggtgaaacag
    20041 ccaaggccgg cgactgggat aggttcgcag aaacgtacaa gcaaatcacg gagagcacca
    20101 acatcaagcc cgtcggtgcc atccttgacc gcctcaatgc tctgtggccg ttcaaggatg
    20161 cgaccgggtt cctggacaac ggctgcgggc cgggaaccat catggccagg ctgatcgacg
    20221 tgtacggtac cagccttccc ccctcgtgct ccctgctatg caccgactac tcccccgcca
    20281 tgatcaagca ggtggaagcg gcccgggaga agcaggagcc ggcttccctc tgggccaggg
    20341 tcgatgcccg ggttctagat gcactcgacc tgaggggcat cggcgacaac tcgctcagtc
    20401 atgttgccgc tggactggtc agtaataccg cccatgggca aaaggcatgt tttcaagcac
    20461 ccaccctgcc gacgctaacg ttactaagct ctacaacttg actacggacc cccacaagtg
    20521 cctgaccgag tgcagacggg tgctccaacc gaacggggtc ttggccgcgt cggcatggga
    20581 ggggaacgag tggctcgaga tgatgcaggt cctcccgatc atcaaaccgg agctcaagag
    20641 cgccgtgaag gcgaagtgga ccagcgtctc ggctatgaag gccgacttgg cggccgcggg
    20701 cttccgcgac gtggaggtcg agtcggtccc ggtccaggtc ccctttgagt cgcacgactt
    20761 gttcgtcgac accctgctga cctaccaacc gcgcatgacg gctttgctga gggactttac
    20821 cgagcaggaa aaggccacct tgaggaagct cctcatcgaa gagatgaaag tctactgtcc
    20881 aaccgagccg ggggcgttga acggggtggt gctcgtggca acgggttgta aataggggga
    20941 gtggcctgac atgcagttgg ctgcacttag agatcgaaac ataaaacata aaccgcaata
    21001 tccggtccca gtcggtctgt tcaagctgta gagacgcctc atggatggat atttgagagc
    21061 aatgctaaac tacctactct tcttggcggt caatgagctc cttttcgagt aattaggaga
    21121 cgttcgaaaa actgagcatg atgatcactg aaaagcgcat tcaccatatt agtcggaccc
    21181 cacattcaga acacccccta ggttatccca aataattatt tactccatcc gtgactgtca
    21241 gggtaatatg taagaatcta cctgcattca aataatcaac atcacaatag tcaaaagtga
    21301 gtaaaactcc aggaatatac tccgcctatc atgtgaacag tttaacaaag atgctaattt
    21361 aggaactaac cagattctta aatgaacggc atgtaatact ataatggcga gttagataat
    21421 ttaaaatgcg aatataaggt agatcattta atatactgtc tctagctata tcttgatgta
    21481 aattcgataa atatgtgctg ttggctatgg ggttgaaata tgtgaggtcg aacgagtatt
    21541 atgtatggga aatggtgtta gaataggggg tgctcggaat atcatagggg gagagctttg
    21601 gtagtgttta gggactcgtg atgagcgaaa gggggaaagc cgaaagaggt gaaacgcatc
    21661 attccgtcct accaagatgc ggcgcggcaa attctcggga ccgaggagta cccccccacg
    21721 cgatggggca aagattctcg cctcatagtt agaggttcga aacttgtcaa agcagggtgg
    21781 cgggtgcgat ttcccactcg gtcgctaatt acttggacta tgggatctga cgcgccgaag
    21841 ccaacccctg agttcggtcg ccttccggtc gccttcatgt ctaggcacac caccccgatc
    21901 tataccgagg ctagtctaag tctgacagcg agcacattcg gggcctttta ccgacttcca
    21961 cgcggatgtc gttgcccact acaacacgat ggaaaaggat gctttaccat gtgatggttg
    22021 gggtgaaccc ccctacgaga tttaaactcg agctactaaa ccctctgagc gcagcagccg
    22081 tggaggctca agggctaatt aaatagtctt cagtgctgtc aagtgtaacg tacctttcac
    22141 aaacaaccta accaagactt ccaagtcaac atcatgcctg tcccgctcct tgacgcatcc
    22201 caagttcggg ctggccctga ggcgcgaaag agcttcctca gggacctgat ccagagtttc
    22261 caggactatg gattcgtccg gctcacgaac catggcattc ctccggcgag ggtgaaggaa
    22321 atgtttgagc tggtacgttt aacggtggcg tggaatgccg ataattacat ttcgtgtatt
    22381 tcagccccgt gctaaccact ctgacaacca ggcgggtgaa ctgttcagtc tcgacaccga
    22441 aactaaactc ggattcgcca acattgccga tggcagcccc cagcgcgggt atagcgctat
    22501 tggcgttgag aagaccgctt ccttgcacgg aaagctgatc ggccgtaacg tggatgagag
    22561 gctgacagat gctagagtac gtccctaaaa cacttgtttt attctcagtg aacattcacc
    22621 tcgccggccg gccagaacgt cttgggatat tccgctgaca tatcggtgcc ataggagcac
    22681 tttgactgcg gctccccgct tgatgaggag tacaggaacc ggtggcccca gtccgaatct
    22741 cttggctatt tccggaagga aatggaagcg ttctacttcg agatggaaca ggtaactgcc
    22801 gagctgctca gttggctgga agagggactg ggcgtgcccc ggggcacgtt caacaatctc
    22861 gtcacgcacg agaagaacgc cagcgagctc cgtctgaacc actacccccc cgtcccggcc
    22921 tcgcagctcc tcagcggcca ggtctcgcgc atctggcctc acttcgacct gggcgtcatc
    22981 accctgctct tcacctccgg ggtgggcggg ctcgaagtgg aggacaggaa ggcgcccgga
    23041 ccgcagacct tcatcccggt cgaggccgag acgcaggacg agctcatcgt gaacatcagc
    23101 gagaccctcc agcgctggac cgacgacaag ctcccggcgg gcctgcaccg cgtctcgact
    23161 ccgaaggagc tcgaggagag gatcaagacc gacagcagcg tcgagatccc gcggcgctac
    23221 agcatcgcgt atctgtgcaa ggctgaccgc cacgcctccg tgggcaccct cccggccttc
    23281 cagaccgagg agaagcctca ctaccaggag atgacggcgg ccgagtatca ccgtcagcgg
    23341 ctcttgacgg cctactaagc cttcggcagg agaagaagta aaacggggat agttttgatt
    23401 tggcctggta gattaaggca tgtgtagggt aggctgcttt cggtagatag ttttcagtta
    23461 tcaatgacaa aattgtgaat tcaaagacaa cataaattag tgcagtgact gcataattac
    23521 atgccttttc tctggttttt ccttccctta gtcaataata acatcgtctc tgtttctgct
    23581 cgttgggcag ccgtatgagt gcataaatta attagtggta gatagccgcg tttcatgata
    23641 caataattaa taattagtag ctaattactt tggcgactga cttcgccccc gaatgacacg
    23701 atttgcacct ctaaatatca cattgctccc ctgatcttat gctagttgtc atcatgattg
    23761 attaattaat acaggttttc aagtgtactg gaaataaagg ttgtaccgtt attagttacg
    23821 ttaatgtttt ttatatttaa ttaaacaata ataataatta gtactgtttt caatccatgc
    23881 aatagactat ttcatgaaca gattttcgat gtcgtcgcct gaagcgcctt taccacggtc
    23941 tcctttgcct cgcctcgttc taaggttgcc aaccctctcg cagttgcgcc gccgggagtt
    24001 gtgacccttg cagtgacggc agccgggtct tgaccagaga ctaccaattc cgctgcgcct
    24061 gccatggtga gagccgccag gtgtgtcgct ttgctcctct cgatcccctg tgctacggca
    24121 gcatccacca ttgcctcgag gaaccaagag aaaaacgcgg tgcccgaagc gcacaacgcc
    24181 gtggcggcag gcatttggtt cgtgctgaca gggacagggg ttccgatccg ccttaggacc
    24241 tcgtgcccta gttctagcac ttcacccggt atggaagcgg actgaccacc gacgacggta
    24301 acggacttct gtcgggccgc tgctacgttt gggattgcct ggaggatgtg gcagggacgg
    24361 aggccgggag actcactcct cctcgggttt ccatacaagc cctcctcgag ctttgccacg
    24421 gacacgccgc cgagcatgct taccagcagc tttccggaga gcgcttcccg catgcccggc
    24481 atgccgagga cctcggctcc ttggtgaggg tgacacgaga ggatgacgac atcggctctg
    24541 cgtgcggccc cgacgttgtc gccgacgacg aactcgacgg aacaagctcg gtcgccgacg
    24601 tcgtccgtta acaccgtttc cgaaagactc tgcatcttgt cccgggtgcg aacggacacg
    24661 atgatccgct caagtgtgtg ccggttatcc tgtgccggct cggttccgtg accggcctgt
    24721 gttgccgtcg gcagcggcgc caacagcccc tgcaggacgg cggtcccgag tttacctggg
    24781 atgaattttt ttcaatctca ggcctcggac agtgggggat gatgccgtga ctctggagtc
    24841 cggagttcta aaccaaagcg agactcactt accacatcca atgatggtca aggtaaaccc
    24901 ggacggcgac ggggaattgc tgacgctgat gacgccggca ggtgttcggc catcgtccac
    24961 ggagcccatg ttgcgccgtg aattgttgag gagctgtctt gagccgaaag cggcggggat
    25021 tgtcagggtc tcacggatcg ggatttctct ccaccgggcc ggtcaaagga gcgataatta
    25081 acgatgaggc ggtagtgtaa atggttgtac ataccctgcg cgagttcccg tcaagcgcgc
    25141 ggttataatt aaggcgcggc ggagaaagtg accgagttgc cgaattgggt agggagtttg
    25201 ccgaattaat acggagtagg gggtccacga ttcctggtgt tgcgttgatt ttcggttcgg
    25261 ctccacgcgc cgaaacgaag gctgggctga gagcagggag tctatgctta cacttcgcct
    25321 ttgcatgggc agtaattatc agacaactaa tggatatcta attatctttt gtttctagcc
    25381 agatgctttg gctgtaacta gccaatcact cgacctctcg tcacaaagaa gtcctttctg
    25441 tttatgcccc ccaaatttct aaaggcagct tgagcggcca caacaacgaa ttaattagaa
    25501 gaacttgtca acacaacacc aggtcagggg ctgctatctc agatcttccg cagaaaaaca
    25561 caatggctcg gataaaccgc cagacggctt accaaaaagc cgacgagatc gagttctcca
    25621 cttcttccgc agatccgctc gcggcatgga ggatctcggg aatcaagggt cccgtctggg
    25681 agcagtggta ctttgatagc gtcgcggacg acgggaagtc gagcgtcgtt ctcacgatcg
    25741 cacgggatgc gagctacgca ctactcgggc gcggcacgct gcgcgtcgag ctcgacgtga
    25801 ccttcgacga cggctcgcac tacaacaacg tggactggat aagcgaggcc atcgtcgagg
    25861 acaggagcgg ccccaagaac accggcaccg tcgacggctc gtggacggcg cccaacaagg
    25921 cgtaccgata ccagatcgcc gccgacggca gcgccgccaa ggtcgagatc gccacgcccg
    25981 aggtccaggg tcacttcacc ctggcggcct tgtctccacc cctctacccc gagggtgaga
    26041 cacaggagga gctcaaggcg tccggcaaga cggccacgac ggagctgctg cccaagatcc
    26101 acctggtcca ggtcatgccc accgcgacgt tcgaggcgga tctggtggtc agagaccgcc
    26161 tggtgcgatt ccgcggcatc ggcggccaca tgcacgcgtg ggcggccggg tcgtggttcg
    26221 acacgacgct cggctggcgc gtgacgcgcg gggtggccgg cccgtacagc gtcacgctga
    26281 tggagtacac cgacatggac ggcgtcgtgc actcgagcgg cttcgtcgcc agggacggca
    26341 agaagctctt cggcgccaag gaggtgtacg cgacgccgcg gtcgtcctcg gccctgcagc
    26401 gcgcgctgcg ctacacgggc gccggcaagg acgagaggaa gcccaagcac acggtccggt
    26461 ggacgccgac gtacaacacc ggcttcgccg gccggttcgg ggactcgagc accggcgcca
    26521 tcctcagatt tgccgccgcc gagggcgagg agtaccagtt cgagctcgtc caccgccgca
    26581 aggccttcga gtatctgttc gggagcagtg acaccggtct gaccgccttc ctgggcgaga
    26641 tcaagggagg gaaggttgga gaggaggtat acagaggtgt gcagttctcc gacgtctgcg
    26701 tattaccccg tgagtaatta tcccagtccg gctctgctct cctccgccga atgtctacta
    26761 attaacattc tggtttgcag agggtatcac caaggtttat ttcttcatct gcatgctgat
    26821 cgccgtgctc acattcggtt acatcaatat cctagagaca aacacctaaa gaaacagggg
    26881 gttattagat gtgacaagta ttaaattact ccgtagcaca ctctacgatc acttttaatg
    26941 actgttcgaa ggaattgggt ttgtctggat gtggagttgc tggcatcaaa ttgagcacta
    27001 ggtatacgga tactaacgca gatgaattta atctccgtcg tgatttctgg atcccacctt
    27061 tacaagttct gaagttggca tgctggttct cctattcaag tgaattgatt ttatgtctgt
    27121 gattactgta aacaagcgta ccttgaagat acagaaattc taaatatatt tacctgatta
    27181 ataatatcgg cagtctattt actagtagga taattacacg ttcaagagtc gaagaaaact
    27241 agactttcta tcaatgactc taattagtaa acactccttg acatattacc tatcttggta
    27301 tctcttggca tcttttttcg atggagggat tttccagtga tcaatatctc tacgtatatt
    27361 acttaaggca tattattaat cgggtagtat agttagaatc cactgatcct gaaccacata
    27421 gatataatta tacgtgcagt gcgcgtgtgt agagggtggg aaagtgctgt gtactgaata
    27481 tttctcaatt ccgagctagg tccgtatctt ggagtgtgtg caggccccaa aaatgcaaag
    27541 aggacaaggc gcttggcggc cacagatctg cgatctacgc caatcgccgc cggtacgggc
    27601 cggccgaata cgccgaagtg gccattttac ctgggccgaa gcgatgcaac cgaaatctgc
    27661 tagcttcgcg aagtccactc cgacgaatcc caaattaccc aaggtaggta gttaagtaat
    27721 taatgacata atatttaaca tgttgaagac aacgctcact gcacacatgc ccacattcgg
    27781 agtcaaaagt aacggcatag agccaagtat tctctgttat tgttgttaat ggtgcaatag
    27841 gaaactttga gattcctttt tccaaagttt cattttaaag cgaggaaagc tgacattcga
    27901 atcaacgaag atggagcgaa tcccagatac catgactgct gttgtgtttg acgggccaca
    27961 caacatctcc gtccaacaac gcccaacacc aaaaagtacc ccaaccattt ctgactcgat
    28021 ctcgatcatc tttctactcc tgggctagac tactgacatc ccgtagtcca ggatgacgga
    28081 gacatcattg tcaaggtgca agccgctggg ctttgtggtt cgtacgtata ccatcactac
    28141 cgtacactac cgtaccttac tttacattaa taaccatctc aatcctgagg aatgtcagca
    28201 ctttctaatc cgcccacagg gatcttcacc ttcttcgtgg cctagagaag accaaaacaa
    28261 cgggctttat catgggccac gagttttcgg gaacggtagt ggcagcagga agtggtgtca
    28321 agactgtgag cgttggcgac aagatcgtct caccgttcac ggtatcatgg tgagttgaca
    28381 aatgagattg cctaataata cctgagttct ccaagctcgc tgacttcctt gacaaatcag
    28441 cggagcgtgt ttctactgca aaaacggctt ctcgtcccgg tgcgtgcatt gcttggtctt
    28501 cggcaccgaa gggctggcgg gcgcccaagc ccagttcgtt cgcgtgccgc gggcggacgg
    28561 caccgtgatg aaggcgcccc ccgaaatcag cgacgacgcc ctcgtcctca tggccgacgt
    28621 cttccccacc ggattcttcg gcgccaaaaa cgcgttcgcc gggctgccgc ggacccagcg
    28681 cccctccgac gcggtagccg tcgtcatcgg ctgcggaccg gtgggactca gcgccatcgt
    28741 ctcggcgctc gagtacaagc ccaggcacct ctttgccatc gacgccgtgg agagccgcct
    28801 ccgggtggcc aagtatctgg gggcggagcc tctcaatgtc gcggacggtc aggagaacat
    28861 tgtgaagagg atcggggagc taacggaggg gaggggggcc gacgtcgtcg tggaggcggt
    28921 cggcctcagt cctgctctga gaacggccta cgacattgtc cggccatttg gaagcattag
    28981 cagtatcgga gtccacaatt catcggtacg cgagaagcgg gtcgaagaga gcgactcctc
    29041 gtaatatgga tttgatgact gacatgcggt tacttatata attaatagat gccatttacg
    29101 gcaacggaag gatacgagta agtgttaatt aacaccacca caccaccacg ggatctcttc
    29161 cacctgacga gtataattac tgacacttgc tccagcaaaa acgtgaagat ccagatgggc
    29221 aggtgcccag tccggtcaat cttcccagag gcgctgccgg tgttggccaa ggctcaacac
    29281 cgttttgggt aagccaactt cgatgttgcc tcccttaggt acacatgatc tccacgtaat
    29341 tagttctcac accacttcta ggttcatgtt tgaaaaactc gtacccctgt cagaggcggt
    29401 ggaaagctat gcactcttta gcgagatgca ggttcagaaa gtaatcttca agccgtggca
    29461 gcgcttcgag agggagaatc gtaatacccg tttgtgaatg ggcggcggcg ttctggtggt
    29521 ggtaagctgt aattaagggt tcaagtaaca tttggttgtc ggcacgtctc gaattactag
    29581 acaaaaacaa aagtgtgcag agtgcagatc tatcttgttg tcagattcag gacttccaca
    29641 agcgtttccg aacctgttgt cactttgcat cggtaccaat acaccgtctt gcgccatgtc
    29701 cttggactat tcatctctcc agctccgtga ctcggaagta attaagacgt gcctattgtg
    29761 acacttaagg ctcagaacat ttttgggggg ggggggggag gggttaagag aacaaggcta
    29821 aggaatggta ctgaaaagat atatatatat atccatagat acttccaatg aatcatagga
    29881 cttgtagcac gcgtgactgc ctgaggtggg tagataatta tctgctaact acacaaggcc
    29941 gagcttctta gcttcagttg caataataga cccgagctcc tccttgagcg aggggtggtg
    30001 tggctgccag ttcagtgctt gcctcgcccg ccttccctcc actcgagcgt tgcatcccca
    30061 gaagaactgg cccatcggca tgatcttgga cgcctcagtc ggctcaatgg actcgggttc
    30121 ctccacctga gtcaggaacc cctgagcagc tgcctcagcc gagacggacc gtgccagctc
    30181 gctccagaca tgctctccgc cctcggcaaa atagaagcct tccgaaccgc cccagacggc
    30241 cggcccgctc ccagtctctt ctcctccagc agcagcgtgc tcgaccaact tgaggtacaa
    30301 ctcggagaga tcgtgtacgt ggacgtttgt ccaggcggac ttgccctcgc ccacgacaat
    30361 ggcgcgcttt cgctcgagag tagcccttac cagctcgtgg atcgccgtgg ggcggtactt
    30421 gaggatgcct ctgccgaggc cgtaagccga gccggtgctg acgacggcgg tcttgacctg
    30481 gttgggcagc tggatgccga cttgtcgtac cgcattctcg gcgccgcggg ccttggcaaa
    30541 gtcgggcacc gaaagcactt cggccagtcc ctctaggtcg ttgaagacct tgtcgctgcc
    30601 ctggccgtac cggcctttga cgacgtcgtc gtagatcacc gtcccgctgc ccatggtgtg
    30661 gatcaagaag ccgggcccgg gccgcgtgcg ccgcgccagc cctcttgcca gggcctgcac
    30721 cgatggctcg tgggttgcat gggcaaaatc tggatgcatg caattacatc agtcagttat
    30781 cagcaccggg acaggacgga cgccgttggt taaacctact gcatacaatg tccgtgttgg
    30841 cggcttcctc ctctagaagg tcgccatcgt ccaggcttcc gtaaacgatc ctgaggcttg
    30901 gatgggcttc cgagacgaga gcacccttcg ccttgtctcg caccaggcat gagatctcgt
    30961 actccgggtg tgcctgcagg atcgcataaa cggcatcccc gccgagatac ccggtgacac
    31021 cggtagcaaa gattttggtc attttttttt ccccccttgg tcatcgaccg ctgttgagat
    31081 ggtatgatgg cagataggta attagcaggt ttctcacctg gccgagatct ggccattgtg
    31141 ggaacatggc accgggcatg tgtcaatatg gtatggcaag tctggaacac tctggtgccc
    31201 gctgctgcgc cgatatccat tccgaaaatc cccaaacagc gggatttcca attcgggtag
    31261 gcattaaatt aatcgaggcc gcctgagtgg ggccgtaacg gagatcggag ccgctcccga
    31321 actcttcggt cacatttgtg attggtttcg gtaggcggat ccggcgaatg agatctcgct
    31381 cgggcttccg gtgttaatta gtggggatac tctagtgccg gccgacatcg agagcggtgg
    31441 ttacggcgat ggccagtgcc tgacaaaaag acaacaacaa aaaaaaaaaa aaaaaaaagc
    31501 tcaatagata cgccttaact gtcctcatgg gctacgagga actcaggtta gacacagcag
    31561 ccgacctagg aactaccccc ttccctttgc cagtctaagc tgttatgact gagatgacaa
    31621 ccttttccat ctttgggcta gaacgcccgg ccgtgttggc cctgtccatt gcggttggtg
    31681 cgtcctatgt catctacctg gtgacgatca cgattcatcg actcttcttc caccgcatct
    31741 cccacatccc cgggccaaag cttgctgctc tcacatacta ctaccagtcg tactacgact
    31801 tcttcccgca ccagggtcaa ttcatcttca aactcgacga gctccacaga aagtatggcc
    31861 ccatcgtgcg catcggaccc gacgaggtcc acgtcaacga tgccaagttc tacaaggaga
    31921 tgtacggttc ctcaacacac aagcgcaaca agagcccgat ctggtactgg atgcatggcc
    31981 tcggggccgt gggcgaccag agcatgttca tcacgctcga ccacgaccat catcggctcc
    32041 ggaaggccgg gctgggcacc tacttcagca agcgcaaggt ccaggagttg gaaccgagag
    32101 tgaaggagaa agtcctacta ctacggcaga ggcttctgga acgcgccggc ggtgccccgg
    32161 tcaatctcaa ggatgccttt ggtgcaatgg cgctgggtaa gcaagccaac atccgggaac
    32221 ggaaccgttg agaggagaga gccccggaac agaaaagagt tccagagtgc ctaggtattt
    32281 taaaaggtat tttaattaac catgcgcttc tttaattatt agacattatc acgcagtact
    32341 gcttcaaccg atgcttcgga gcgcttgacc gcccagacct cgggcgcgag atgaacaagc
    32401 tgatgggggt cggcgttaag atcaacccct ttgctcgcac gtttccgacc ctggcccgca
    32461 ccgtgatcaa gctgccgagg tgggctctca aatggagcgg cctcgtgtcc accacggccg
    32521 agttcctcga cctcgccgac aggctgtccg ccgaggcgcg gaacgaggcg atccgcgacc
    32581 tcgccagcgg caagtactcg cagacggacg atgccgactc gagaacggtc ctccactcca
    32641 tgatgcggag cgacgtcctg cccgagcacg agaagacgga gaagcggctg caggcggacg
    32701 gcatgacgct gatcgcggcc ggcttcgaca ccaccagccg caccctgacc gtcatcttct
    32761 accacctcct gaccaaggac cacatccggg cccgcgtgct cgacgagatc cgcaccctga
    32821 tgccgacccc gacctccccg ctgccgaccg tcgcccagct ggagcagctg cgctacctga
    32881 cctgcgtcat ccacgagggc acgcgcctgg cccacggcgt cgccggccgg ctggtgcgca
    32941 tcgcgcccga ggaggacctc gagtactaca gccccttcga cgggcgccgg tacaccatcc
    33001 cgcgcggcac caccttcggc cagtcgtcct acctggtcca cacggacgag tccatctacc
    33061 cgaacccggc cgagttcgac ccggaccggt actggaccga cgacggcagg ccgaccgacg
    33121 cccagcgcta cctcgtcccc ttcggcaagg gcacccgcat gtgcgtcggc atcaacctgg
    33181 cctgggccga gctctacctc accattgccg ccctgatcgg cacggtcgac atgaggatcg
    33241 cccccggcac gaccgagcac gacgtcacca tggtgcaaga cctgttcgtc ggcgtcttgc
    33301 ccgagaatcc cggcgttcgc gtgaacgtcg tcgggcacct ccaggcttaa ttagcctatc
    33361 taggtagttg cgggtgatag ggcaatcaat gtcggtccgc atatcacgag caaggttttg
    33421 ggcgtggatg gaaggaggag aagagtgaaa ggattgagcg gagctagcca gaccatcaaa
    33481 attgttacgc accttactac ctacctacct aggaggatgc agtagaaaat ggccaagatc
    33541 ctgcgtggct caggagtggc atgcaatgaa tgagtttaag actccaaatc tgaccaaatc
    33601 atgacaaaca ttgctttcca tcgtgaggct tgatatgcct ctatcaaacc atttacttgt
    33661 ttggatgttt ttcaattttc tcccccgaat attcttttcc ttagtttctg gtcaatgtta
    33721 cgttttatat tcctcccttg tgttgtatat gctcttcttg tctctctcgg catcagatca
    33781 atcagattcc gtgcatctac gccttgggag cacctaaact agtataatca agacaaactt
    33841 ctaagataag atgcaagtgt gtaatagata ttacatttaa agttgattaa tatattgaaa
    33901 ctagttagag ctgtagtggc ccaaaggagg gggggtggcc caaatccagg gggaccgact
    33961 ttatgcttta cattaaaggg gcagaacatt caacaccttg ttaagcactt gtccagctcc
    34021 tcaggtccgt gaccgacaac ctgagaacgt ttctgagctc tacggcacca tatgctccat
    34081 gtagtaagca cctgggtcta ggtatgtact gtatgtgaca tatctggtgt ttaagctgaa
    34141 gcaagggtac ttaggctagg tagggtaagt aattacagac acgtgctggc aacatctcgg
    34201 tggcgcactt cacgattttg gtcgaccgac aagcccacgc ggttatggta tgagagaacc
    34261 cgttcatcca actaccgatt actacgagaa accgtaacaa catgatgaaa tgaaaaaaaa
    34321 aaagctgctg taactatctc accactgctg agatcgaccc ccccccccgg accaacaacc
    34381 ccaagatcga ccaaccagca tcagtgatag ccgtttgtca caaagccgtt ttcgtacccg
    34441 ttcttcacga agccgtttgt gtacccattt tcatatccgt tctcgtacac cctcttcgga
    34501 ctcgacggcc tctggatgcc cagcttctca tccaagaact tgaaagtccg gtactgcagc
    34561 agcggccagg cgccagactt tgcctgggcg ccgccctcgg accaggcctt gggaacccag
    34621 agctccttct gcccctcggg cacgttgacc aggtttctca tgatggccga cgtgctcatc
    34681 tcggccagga acagcttcgg gtcacccccc gcgccggtga ccaggacggg gcaacggacc
    34741 cactcgaggt agtcccggtt ggcgcgcccg cggttcttgt tgtcggccgt gacggtcctg
    34801 tcgaggcgga aggtgtactg cttcatgtcg cggatcatct gggccgggtt ggagctgccg
    34861 aacatgtggc agccctgggc gaaggtgtac ttggtggcga cgtcgagctt ggcgtgctcg
    34921 cggacggcga agtcgacgaa gccgtcgccc atgtagttgc gctcccacgg ccacatgaac
    34981 caccgcggca tgcgcgacat ggcgaggtcg tagaagtcgt agaccgggtc gacggcgacg
    35041 caggccttga tgcgcgcgtc cgccgccccg cgcagcgcca ggtacccgcc cagggactgg
    35101 cccgtgaccg cgacggcgtc gaggtcgagg tcggcctcgg ggtgctcctc ggcgtacgag
    35161 gcgaggaagt ccaggactgc ctcgacgacg atctcgccgt cgggccgcag gggcacgccg
    35221 tcctcccgca ggacgagccc ctgacctggg ccgtcgaacg tcaggacggc gtagcccagg
    35281 cctggccctt cggcgacgtg gaggaagtag agctcctctt gggtggagtc ggcgccgccg
    35341 atgcagatga ggacgggcgt cttgcgtccc ttgagacgtc gagacggggc ggggagatgc
    35401 agccatccgg gaagtcggag gagcggtgcg cggtactcgg gcggctggaa cgggatgcga
    35461 acgcggcgta cgtcgtgctc catcagcttg gtcgcctgct caaagttgga gatgctgcgg
    35521 tggtataggg acaggaagta gggctgctct tcggcgggca tgatcgggaa taggtactgc
    35581 gcgcagcgga agtagttgct ggcgcgcagg aacgcgcccc tggcggccga gaggtggccg
    35641 tttctctgca tctcctcggc ccacgactgc gtcctctcag ccagggccaa gaatttgcgg
    35701 ttccagtcgt cagcatcgtt gggaatgagc gaggcgacaa gctcgaggaa ctcggcagcg
    35761 tcgcaacccc cgtatggcgc ggcgcccagc agccgcagca gctcaaggtt gtaccatttg
    35821 tattcgaagt aatggcggtt gggcgagtat gtgaagaatg gatacatcgc agggagaatg
    35881 cagaatgcgt actgctccgg tttgacggca gttgtatcac tgggtaatta attacggttg
    35941 actttcaaag cgcgaagcgt gagtcgacgt cgacgagagt gtaattatgc cctccctcat
    36001 taaggtactc aacagtgctt ctcaggcggt tggggggggg ggagaggcgg agcattaagg
    36061 gagcaagcag tagcagcaat aactaagacg acgagtatgg gatcatggca gcaccgcagc
    36121 accgcagcac cgcagcaccg cagcataccg attcgtacga gtatggacaa aattatcgca
    36181 ggccaggatt gagcactcaa ccatccggtc ccattaactc accgtggtcg gtcggtcacg
    36241 gagagtgcga cgacctcgac cggctggaac gctgccgtaa gtaattatcg gtaccggccc
    36301 tccaaggcct gagtcaggtc tagctaatta gtttaaaccg gcttacaaaa gacatgatcg
    36361 gccccccttc aatgccagcg gtgcagtgta atccatacgg ccaggactat agagggcccc
    36421 atcgagcccg aaagaaggcg atgagcaaat cgacccacgt gcaacgacga gacaagaggc
    36481 attgtctcgc aggaggcaaa aaaaagattt gaagcccaat ggagggaaag ctcttccaat
    36541 gcgtaccgtg taaaagtagc cggaagtcac cgaaagtcac cgtaaatggc cgaaagtggc
    36601 cgaaaatgac cgaaaggagc agccaactct gtctaaattc ctccggttca tggcttcctc
    36661 tgacagcttt tctccctttc taagactaca caagcggttc tcgactctgg cgtggcacgt
    36721 aatcgcccca gcttccaaga ctccgaagcg ttagcttacc tttcttggct tgcccgtctc
    36781 gtcgcagtca gccaagaaga accactcgag tcccttcgtc ctttccgtca gtcactcaaa
    36841 ctgctctaca attaattata gcagacacag ccaagaatac agccaaaaaa atacagccaa
    36901 aaatacagcc aagaatgtca cccgcagacc cacctaacgg cacgccgcgg gagactgccc
    36961 cggcatccga cgaccgggaa gccatgtcag agggggcggg tactggtact gggtcagcag
    37021 cggagagcag cgaggccgcc gccaagaagg gcgacgaggc gggcgaaggc gacgctactc
    37081 ctcccaagac gagccactcg ctgcgcttct ggggtatcgt ggcctccctg gcgttcacgg
    37141 ccctgtgctc ttccatcgag ggtaccatca tcaccagcgc cctgcccacc atcagcgccg
    37201 agctcggcgg cgacagcagc ttcatctggg tccccaatgg ctacttcctc gccaccatgg
    37261 tgatgctgcc gctcatggcc caggccgcca acctgtttgg ccgccgctgg ctgactttga
    37321 tctcggttgc catgttcact ctgggcagcg gcatctgcgg cggtgccaac tcgcccgcca
    37381 tgctgattgg cggccgtgtc gtgtaagtcg aaaaagtctt tcttggcatt cacttaccaa
    37441 ttcaggtaac catgtcgcta actgactggt ctcttcttgt tcttcttagt cagggtctcg
    37501 gcggtggtgg tatcgccttg atgatcaaca ttgtcctcac cgacttggtc ccccttcgtg
    37561 agcgaggcaa gtatatggcc atcgtccaga tggtctccgc cgtcggtgct gccctcggac
    37621 cattcctcgg cggtcttttg accgagcgca gcacctggcg ttgggtcttc tacatcaacc
    37681 tgcccattgg tggaagtacg tctgcctcct ccttcccggg tgccccagtc agtgtgggag
    37741 agccagacgg actgacatgg attgtgacag cttcgctcgt tgccttgttc ttcttcctgc
    37801 gcgtcgccac cccgccggga gggacctggg ttgagaagct caagcgcatc gacttcatcg
    37861 gcaatgccat cttcatcgct gccaccgttt ccgttctcat cggcgtcacc tggggtggcg
    37921 ccgtctaccc gtggaaatct gccaacgtca tcgtgcccct cgtcctcggc ttcgtcggga
    37981 taggcctctt cctggcttac gagtggactc tcgccaagaa cccctcgctg cctcgaggcg
    38041 ctatcgtaga gcgcacagcc gctaccgtcc tcgccgtcac gttcctgacc accctctgta
    38101 cctactgggc cttctacttc atgcccatct acttccaggg cgtgaaggcc aagtcggcct
    38161 tctggtccgg cgtcgacgcc ctgccgctct tcgccggcct cttccccttt gccatcatcg
    38221 gcggtattct cctctccaag ttcggccgct acaagccgtt gcatctcgtc ggcatggcca
    38281 tcgtcaccgt ctcgttcggt ctgttcagca ttctcgaccg gaactcgagc accgccgcct
    38341 gggcttgctt ccagcttctc tgcgccatcg gttccggcct gatgattgcc atcctcctgc
    38401 cggccatgca ggcgccgctt gacgagagtc tcgtcgccgc ctctaccgga gtctggacct
    38461 tcgtccgggc tttctcgacc gtctggggcg tgactattcc cgcggctatc ttcgacaacg
    38521 aggtggccaa gaaggcggcc gcctcgctga ccgaccagag cctggttgga tacctcaccg
    38581 gcggcaaggc gtaccaattc gccacgcagg aattcctcga cagcatccgg gacccggcct
    38641 ctcgctccga ggttatcgac atcttcacct cggtaagttg cttttccggg accccttttt
    38701 ctgccccacg catttgtgct gacagtatga cagtcgatca agattgtctg gtacgtgggc
    38761 actgcctttg ccgggcttgg ctggctgttg gtctggctcg agaaggaggt gactctgcgg
    38821 tccaagctga acacaaagtt cggaatcgag gaaaagaaga agcaggagga ggatgaggag
    38881 aaggccaaga acgaggggga gaacaaggat ggagaagaga gcaaggcggc ggatggagcc
    38941 aagagggccg agctgagcgc atgagcgtcc ctccgacgcg tacagtttga cccttcgggt
    39001 ttaattaacc cttcttcgca ccctctctgc actcctcgct caccctaaga taccctttca
    39061 acatgaggca ggaagtatat gcctactgcc tcattttcac aggtcccccc ccccctcaca
    39121 atcgcccaag agttttgtgc tttgttctct gaagacagat cgataccaaa gattcaccgg
    39181 aaatgatggc attttacatg gcattgctag actgggcaat cgggataata tgggttaatg
    39241 aacatacagg gttgtaatag aatgatcgca ttgctagatt gccgcatctt acaagaaatc
    39301 aaacttagca tcaagtaatt gatatgtcca ctgttggaca agaggagtga cccaagttac
    39361 cgagtatatg acatgcacgg cgaaaatggc tgctcaagat tctcaaggac ataactccta
    39421 tcgaagtgga tcgaactttg cccatagccg aatcaccggt tgtcttgtgc atcttagttt
    39481 cctcatgacc ttttgccagt gtttaccact tattcggcga tgctgtgttg gcaacagggt
    39541 acaagtacta agttcagccc ccctgaattt gggccacccc tccatttggg ccactattac
    39601 agctttaacc cttaggttcc gatgtatagg aagtcatcat tcagaatacg aggacaatca
    39661 aagtaaaaag gagataaaaa agcagtaaat catgatctgt accttatttg catcgtattc
    39721 aaattttcta gctctccgat aattatactt gattgaacaa tgatatctac tgtacttttc
    39781 gatcctatat tagaagttca tcttaaccat attacctttg gatgtttctt gtgggggttg
    39841 aagagtgcgg gtttgtcttg atttgtactg tacatacggg attgagtcgc ccagatgggg
    39901 gtgggcccaa atctaataat taggcggccg gcttgccgct ggcgagaaca ccgaaactgc
    39961 gaagtagatg gctgagattg tcctacctta cggcggcttc cacgcttttc attttttttc
    40021 tctcaatcat tttgctttcc aggtttctct cttctatttt tctcattctt cttcgcactc
    40081 gcaaccagac agccacaccg aaaccgggtg ctccacctgc cccatcgggc aatcccactc
    40141 aattctgcca aggcccggcc gagttcattg cttgtggggc cggaggaagt gaccgaagtc
    40201 tcatcgggcc ggccccggtc ccgctgcgcc ccgtaagcgg atcccgacac ggaaacttcg
    40261 cgcacaccga aatccctccc agcggcccgg ggccgcgatc gggcccgcga gattgtgtga
    40321 caatgagcgg cacgccgtcg acccggggct ggccatctta acctggcgat ggtgaccagg
    40381 catcgtcggt ctaagactct ctctcctcat catgctgtgg tcgaacacat gatttcatca
    40441 gatccgtcct gatcccacca ggtcgagtcg actctctcgg caagcaagca aataggtacc
    40501 tagcttctca gaacccaaca caacccaacc atcttcttca acagatacga gaaggagaaa
    40561 aaaaaggaaa gaaagaaaga aagaaagaaa agaaagaaag aaaaagcaaa cacaaaacgt
    40621 cagcaacaaa atgggcagcc tccaagacct cccgcccctc ccgacgaccc agacagccgt
    40681 catcacgacg gccgagggcc ggcacgccgt cgcgcgcgac cgagccgtgc cggcgtgcgg
    40741 gcccacctcg gtcctggtcc gcgtgcgcgc cgtggcgctc aacccgaccg accacaagac
    40801 gccggcgcgg gtcaagacgg gcgggctgac ggccgggtgc gacttcgcgg gcgaggtggt
    40861 cgcggtcggg gcgcgcgcca acgacgagcc cggcgacgcg gccgcctgcg ccggcatccc
    40921 ccgccgctgg gcgcccggcg accgcgtcct cggcgtcgtc tacggcagca accccggcgc
    40981 gcccgcctgg ggcgccttcg ccgagtacgt cgaggccgac ccggtcatgc tctgccgcct
    41041 gccggacggc tgggactggg agacggcggc gtcggtcggc ggtagcgtgc acgggtccgt
    41101 cgccctctgc ctgttcggcg agggcaagat gggcctggac atgggcgggt tgaagaagaa
    41161 ggctgcgctg ctgctgcagg gacatggttc tgccgccgcg gatggtgccg ctgctgcccc
    41221 tccgagtgtt ctccggcctg cgcagggtgg tggtggtggt tatggcggag ggtcgagcag
    41281 cagcagcgcc cagctgagca agaaagatct ccagaaggtg gtgctcgtgt acgggggaag
    41341 cactgcctgc ggcaccatgg cgctgcaaat tctccggctg taagcctacc ctaccctacc
    41401 ctaccctcgt cctcattccc agcttcttcg gcgccgcggc tgtgcccgtc gactgactga
    41461 cggtccgtac acacagggct ggatatatcc ccatcgcaac ctgctcggcg cgaaacgcgg
    41521 gcttggtgac ggcgtacgga gcggcggcaa ccttcgacta caacctcgag acgtgcgcgg
    41581 acgagatcaa ggagtacacc aagtcggcgc tgtggtacgc gctcgactgc atcgggacgg
    41641 cccagtcggc ggcgctgtgc tacgccgccc tgggccgcgc gggcggccgg tacgtggccc
    41701 tcgagaagta cccggacagc gtggcggcgc tgcgcaaggt cgtcaagccc acctgggtca
    41761 tgggccccgt catgttcggc cgcgacctcc agctcggcga gggctacagc cagccggcgg
    41821 atccgtcggc ccgcgccttt gcgcgcatct ggtatcccct ggcagaggcg ctcctgggct
    41881 cgggcgcgct caagaatcac ccagtgaagg tggtggcccc ggagggacga gaggaatggc
    41941 ccgaggccgt catacgcggc ctagggggcc tgcgggatgg gaaagtcagc gcgcagaagc
    42001 ttacggtcac gatagcggcc tagcttgtcc tgctaggtgt caggaaatta agggaggagt
    42061 aaataattag ccacttgttg tacggtagac tcgactgttt cgtgtgtact tagttaccta
    42121 gttacctaca cacactcgat gtgggcacaa agcgaacccg tgagacctcg atacatctcg
    42181 gcattactat gataattcac tacaagtact gggggagctg agcgaatccc cttcccaccc
    42241 aatattcatg ctgatctgac caagagcacc tcgtcttggc cccagtctga gaagtgacaa
    42301 acaggtgctc ttacagcaat gcgatgcgac atcagtgcca gattcctcac cgccccacga
    42361 tctccttcac atcgcttgct tcctttaagc cgtgagccag tcgtaatcca gagcaacgca
    42421 aagagtggat cacaagcccc ccgttctttc tgctgcagcc cgctagcgga aggtctcggc
    42481 cgacgggccg acccaaacgc g
//
