BGC0001451: FR900359 biosynthetic gene cluster from Candidatus Burkholderia crenata
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Location: 62,709 - 98,508 nt. (total: 35,800 nt).
This entry is originally from NCBI GenBank NZ_LGTG01000643.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001451
Short description FR900359 biosynthetic gene cluster from Candidatus Burkholderia crenata
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
NZ_LGTG01000643.1
62709 - 98508
via
Compounds
  • FR900359
Species Candidatus Burkholderia crenata [taxonomy]
References
Chemical products information
FR900359 Evidence:
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C49H75N7O15
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BCRE_RS14160
  • WP_050383080.1
 62709 - 64307 (-) MBL fold metallo-hydrolase
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    • BCRE_RS14165
    • WP_050383082.1
    		 64329 - 73739 (-) non-ribosomal peptide synthetase
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      • BCRE_RS14170
      • WP_050383084.1
      		 73729 - 81288 (-) non-ribosomal peptide synthetase
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        • BCRE_RS14175
        • WP_082191961.1
        		 81278 - 90325 (-) non-ribosomal peptide synthetase
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          • BCRE_RS14180
          • WP_050383088.1
          		 90328 - 93405 (-) non-ribosomal peptide synthetase
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            • BCRE_RS14185
            • WP_050383090.1
            		 93519 - 94505 (-) malate dehydrogenase
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              • BCRE_RS14190
              • WP_050383092.1
              		 94502 - 94720 (-) MbtH family protein
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                • BCRE_RS14195
                • WP_050383094.1
                		 94741 - 98508 (-) non-ribosomal peptide synthetase
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                  Biosynthesis information

                  Biosynthetic modules

                  Name
                  Unk01
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14165
                  Substrates
                  leucine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk02
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14165
                  Substrates
                  threonine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk03
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14170
                  Substrates
                  alanine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk04
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14170
                  Substrates
                  alanine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk05
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14180
                  Substrates
                  leucine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk06
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14195
                  Substrates
                  leucine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk07
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14175
                  Substrates
                  D-phenyllactic acid (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Name
                  Unk08
                  Type
                  nrps-type1
                  Genes
                  BCRE_RS14175
                  Substrates
                  serine (evidence: Structure-based inference, Sequence-based prediction)
                  Integrated Monomers
                  Domains
                  adenylation
                  Annotation changelog

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Added NRP substrate specificities
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated reference publication(s) (MIBiG Annotathon)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated compound(s) information (NPAtlas curation)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2018-08-06
                  Submitted
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
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