BGC0001460: decaplanin biosynthetic gene cluster from Amycolatopsis decaplanina DSM 44594
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 276,857 - 343,203 nt. (total: 66,347 nt).
This entry is originally from NCBI GenBank AOHO01000074.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001460
Short description decaplanin biosynthetic gene cluster from Amycolatopsis decaplanina DSM 44594
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "nmayil@imtech.res.in"
Biosynthetic class(es)
  • NRP (Glycopeptide)
Loci NCBI GenBank: AOHO01000074.1
Compounds
  • decaplanin
Species Amycolatopsis decaplanina DSM 44594 [taxonomy]
References
Chemical products information
decaplanin
Copy SMILES
C72H86Cl1N9O28
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • H074_31612
  • EME52961.1
 276857 - 277933 (-) phospho-2-dehydro-3-deoxyheptonate aldolase
copy AA seq
copy Nt seq
  • H074_31617
  • EME52962.1
 278126 - 278923 (-) enoyl-CoA hydratase
copy AA seq
copy Nt seq
  • H074_31622
  • EME52963.1
 278920 - 280146 (-) enoyl-CoA hydratase
copy AA seq
copy Nt seq
  • H074_31627
  • EME52964.1
 280143 - 280805 (-) enoyl-CoA hydratase
copy AA seq
copy Nt seq
  • H074_31632
  • EME52965.1
 280799 - 281824 (-) chalcone and stilbene synthases-like protein
copy AA seq
copy Nt seq
  • H074_31637
  • EME52966.1
 282005 - 282622 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
copy AA seq
copy Nt seq
  • H074_31642
  • EME52967.1
 282646 - 283755 (-) glutamine--scyllo-inositol transaminase
copy AA seq
copy Nt seq
  • H074_31647
  • EME52968.1
 283752 - 284723 (-) NAD-dependent epimerase/dehydratase
copy AA seq
copy Nt seq
  • H074_31652
  • EME52969.1
 284725 - 286155 (-) 2,3-dehydratase
copy AA seq
copy Nt seq
  • H074_31657
  • EME52970.1
 286506 - 287855 (-) sodium/hydrogen exchanger
copy AA seq
copy Nt seq
  • H074_31662
  • EME52971.1
 287887 - 288966 (-) FMN-dependent alpha-hydroxy acid dehydrogenase
copy AA seq
copy Nt seq
  • H074_31667
  • EME52972.1
 288963 - 290015 (-) 4-hydroxyphenylpyruvate dioxygenase
copy AA seq
copy Nt seq
  • H074_31672
  • EME52973.1
 290125 - 291315 (-) cytochrome P450
copy AA seq
copy Nt seq
  • H074_31677
  • EME52974.1
 291330 - 293066 (-) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • H074_31682
  • EME52975.1
 293063 - 293893 (-) alpha/beta hydrolase fold containing protein
copy AA seq
copy Nt seq
  • H074_31687
  • EME52976.1
 294143 - 295429 (+) GntR family transcriptional regulator
copy AA seq
copy Nt seq
  • H074_31692
  • EME52977.1
 295410 - 296282 (-) hypothetical protein
copy AA seq
copy Nt seq
  • H074_31697
  • EME52978.1
 296292 - 297125 (-) LmbE family protein
copy AA seq
copy Nt seq
  • H074_31702
  • EME52979.1
 297127 - 298353 (-) NDP-hexose C-3 methyl transferase
copy AA seq
copy Nt seq
  • H074_31707
  • EME52980.1
 298400 - 299632 (-) glycosyl transferase family protein
copy AA seq
copy Nt seq
  • H074_31712
  • EME52981.1
 299665 - 300885 (-) glycosyl transferase family protein
copy AA seq
copy Nt seq
  • H074_31717
  • EME52982.1
 300906 - 302096 (-) glycosyl transferase family protein
copy AA seq
copy Nt seq
  • H074_31722
  • EME52983.1
 302146 - 303621 (-) tryptophan halogenase
copy AA seq
copy Nt seq
  • H074_31727
  • EME52984.1
 303666 - 304886 (-) cytochrome P450 FAS1
copy AA seq
copy Nt seq
  • H074_31732
  • EME52985.1
 305014 - 306210 (-) cytochrome P450 FAS1
copy AA seq
copy Nt seq
  • H074_31737
  • EME52986.1
 306426 - 307601 (-) linalool 8-monooxygenase
copy AA seq
copy Nt seq
  • H074_31742
  • EME52987.1
 307710 - 307919 (-) MbtH-like protein
copy AA seq
copy Nt seq
  • H074_31747
  • EME52988.1
 307916 - 313414 (-) amino acid adenylation protein
copy AA seq
copy Nt seq
  • H074_31752
  • EME52989.1
 313513 - 325683 (-) amino acid adenylation protein
copy AA seq
copy Nt seq
  • H074_31757
  • EME52990.1
 325994 - 335443 (-) amino acid adenylation protein
copy AA seq
copy Nt seq
  • H074_31762
  • EME52991.1
 335446 - 337398 (-) ABC transporter
copy AA seq
copy Nt seq
  • H074_31767
  • EME52992.1
 337515 - 338345 (-) prephenate dehydrogenase
copy AA seq
copy Nt seq
  • H074_31772
  • EME52993.1
 338528 - 339502 (-) streptomycin biosynthesis operon regulator
copy AA seq
copy Nt seq
  • H074_31777
  • EME52994.1
 340693 - 341301 (-) D-Ala-D-Ala dipeptidase
copy AA seq
copy Nt seq
  • H074_31782
  • EME52995.1
  • vanB
 341298 - 342338 (-) D-alanine--D-lactate ligase
copy AA seq
copy Nt seq
  • H074_31787
  • EME52996.1
 342340 - 343203 (-) D-isomer specific 2-hydroxyacid dehydrogenase
copy AA seq
copy Nt seq
NRP-specific information
Subclass Glycopeptide
Cyclic? no
NRP-synthases
Gene Modules
H074_31677
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
H074_31747
Module ?
Specificity: 3,5-dihydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
H074_31752
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 4-hydroxyphenylglycine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: R-beta-hydroxytyrosine
Evidence for specificity:
  • Structure-based inference
H074_31757
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: R-beta-hydroxytyrosine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: asparagine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: UZDMKOBVVEVI67YDKBV3PKAC, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.