LOCUS       BGC0001463              6707 bp    DNA     linear   BCT 15-FEB-2016
DEFINITION  Pseudoalteromonas piscicida strain A757, complete sequence.
ACCESSION   BGC0001463
VERSION     BGC0001463
KEYWORDS    .
SOURCE      Pseudoalteromonas piscicida
  ORGANISM  Pseudoalteromonas piscicida
            Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
            Pseudoalteromonadaceae; Pseudoalteromonas.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 01:50:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6707
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1236)
                     /gene="bmp10"
     CDS             complement(1..1236)
                     /codon_start=1
                     /gene="bmp10"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 135.6; E-value: 3.1e-41)"
                     /gene_kind="biosynthetic-additional"
                     /note="Bmp10"
                     /product="ferredoxin reductase"
                     /protein_id="AME30282.1"
                     /transl_table=11
                     /translation="MKRCIIVGGGHAGAEAAFELRKRNWTGEILILSSESYLPYHRPPL
                     SKTFLTGESPLKRLYIKPPAAYTKANIDIKLESFVVDVIPDENTIKLSSGDTLSYDKLI
                     LCTGASPRKLTLPGAELANVFSIRTLGDIEQIAKQVNYEQNKKNIVMIGGGYIGLETAA
                     SFKKLGHQVTILERNERVLNRIAAEPIASYVTTLHASKGVTILTNKAVVSLAGNGKVES
                     VICDDGSSFPADLVVVGIGAHANSDLADKAGLITKCGRVLVNDQCQTAAPNIYAAGDCT
                     LAIEPFSGEVTAIESVPNAVQQAKIAVASICGTAQPQRQVPWFWSDIYDCKLQIAGLYQ
                     EYDAVVERAYSSDSKSYWYVKANKLIAVTCINCPSDFQAAKKILRENINISLQRLSNTA
                     TPIAIQDTPLHA"
     source          1..6707
                     /country="Atlantic Ocean"
                     /db_xref="taxon:43662"
                     /isolation_source="open ocean plastic debris"
                     /mol_type="genomic DNA"
                     /organism="Pseudoalteromonas piscicida"
                     /strain="A757"
     misc_feature    1..6707
                     /note="bmp gene cluster"
     subregion       1..6707
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6707
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1250..1570)
                     /gene="bmp9"
     CDS             complement(1250..1570)
                     /codon_start=1
                     /gene="bmp9"
                     /note="Bmp9"
                     /product="ferredoxin"
                     /protein_id="AME30283.1"
                     /transl_table=11
                     /translation="MLKITFVQHDGSTIDTEVEPGMSIMQAAIENLVEGIEGECGGSGS
                     CATCHCYLSEQWSGKVTQPDNNESQMLELVNDTTAFSRLSCQVKITQEHHGLSVTLPES
                     QY"
     gene            1740..2813
                     /gene="bmp1"
     CDS             1740..2813
                     /NRPS_PKS="Domain: PP-binding (12-73). E-value: 3.7e-08.
                     Score: 25.7. Matches aSDomain:
                     nrpspksdomains_bmp1_PP-binding.1"
                     /codon_start=1
                     /gene="bmp1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262:haloalkane dehalogenase (Score: 68.2; E-value:
                     1.1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /note="Bmp1"
                     /product="prolyl acyl carrier protein-thioesterase
                     didomain"
                     /protein_id="AME30284.1"
                     /sec_met_domain="PP-binding (E-value: 4e-09, bitscore:
                     25.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.9e-15, bitscore:
                     45.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.1e-15, bitscore: 45.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKELIDFINNDLLEGAAPDLDENTPLLELGILNSLSMVRLLAHV
                     DQKYGAKIPENNITPVHFENIKTLSMLIKSLSGIVETERAAEVSELERLVCLQESYGIQ
                     RELIDTGNGFKQHTLRVKGKGPLWIMLPALGNPSTSWSSTLRSLQGRHNAIALDLAGFG
                     LSQSSNDAPSYVDHVEFTLQFLETLEEQEWVLVANSAGSMIATEIARRYPEKVKALVCT
                     GFGLVEDVDSWWGDLKKMSSNPEQFLAAAYYHPPKMTPALEDLLNDVLSRPAYHSFLDE
                     YARKSMATTFDGVKVPTLFIAGNHDQIIPPEWSEKAAEKLENATVTRLSRCGHFSASER
                     PEEFVWVVEDFLNKVAM"
     aSDomain        1776..1958
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_bmp1_PP-binding.1"
                     /evalue="3.70E-08"
                     /label="bmp1_PP-binding.1"
                     /locus_tag="bmp1"
                     /protein_end="73"
                     /protein_start="12"
                     /score="25.7"
                     /tool="antismash"
                     /translation="LLEGAAPDLDENTPLLELGILNSLSMVRLLAHVDQKYGAKIPENN
                     ITPVHFENIKTLSMLI"
     gene            2813..4033
                     /gene="bmp2"
     CDS             2813..4033
                     /codon_start=1
                     /gene="bmp2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 269.2; E-value: 1.3e-81)"
                     /gene_kind="biosynthetic-additional"
                     /note="Bmp2"
                     /product="pyrrole halogenase"
                     /protein_id="AME30285.1"
                     /sec_met_domain="Trp_halogenase (E-value: 3.7e-16,
                     bitscore: 47.6, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGFTHYDVVIIGSGPAGSLCGIECRKKGMSVLCIEKEQFPRFHI
                     GESLTGNAGQIIRDLGLADAMDAAGFPDKPGVNVIGSLSKNEFFIPILAPTWQVRRSDF
                     DNMIKQKAVEHGVEYQLGMVTDVIREGDKVVGAVYKADGIEHQVRSKVLVDASGQNTFL
                     SRKGIAGKRQIEFFSQQIASFAHYKGVERDLPPFSTNTTILYSKQYHWSWIIPISPDTD
                     SLGVVIPKDLYYKECKNPDDAIEWGMEHISPELKRRFKNAERQGESQSMADFSYRIEPF
                     VGDGWLCIGDAHRFLDPIFSYGVSFAMKEGIRAAEAIEQVVNGQDWKAPFYAYRDWSNG
                     GQQIAADLIRYFWIYPIFFGYQMQNPDLRDEVIRLLGGCCFDCKDWKAPAIFRNAIEEY
                     DRKQMAS"
     gene            4078..5220
                     /gene="bmp3"
     CDS             4078..5220
                     /codon_start=1
                     /gene="bmp3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 300.4; E-value:
                     3.1e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="Bmp3"
                     /product="proline dehydrogenase"
                     /protein_id="AME30286.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-18, bitscore:
                     55.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.9e-22, bitscore:
                     67.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-35, bitscore:
                     111.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFEWNEAQLSLFEHALSYSSELRSTSHQPGEFPLDLWKSLGDFG
                     YFGLPVDSEYSPCGSGLDILTTVKVLEGLGQGGADTGVLFAGAAHTFACVMPIYEHGSE
                     AIKRELLPLLTSGEKIAANAISEAEAGSDIAKLATTASREGDYYIIKGAKSYVTNGSVA
                     DYFIAYATTNAKFGYLGQTAFVIPADLPGIEVGNSYKKLGLNSAQLNQVFFDEVKVHKR
                     YVLGDEGQGARIFAASMDWERCCLFALFIGVMQRDLDLCIEYANMRKQGDKTISKFQAV
                     SHRIADMEVRLQSARLLLYFAAWQKSKEVDNTKAVATSKLAISEAFVQSGLDVIRVHGA
                     LGYLDEGGVNSSIKDALGSVLFSGTSDIQRELICNRLGLL"
     gene            5217..6707
                     /gene="bmp4"
     CDS             5217..6707
                     /NRPS_PKS="Domain: AMP-binding (16-411). E-value: 6.4e-90.
                     Score: 293.5. Matches aSDomain:
                     nrpspksdomains_bmp4_AMP-binding.1"
                     /codon_start=1
                     /gene="bmp4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     301.3; E-value: 1.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="Bmp4"
                     /product="L-proline adenyl transferase"
                     /protein_id="AME30287.1"
                     /sec_met_domain="AMP-binding (E-value: 6e-103, bitscore:
                     333.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLSEVLLAGMSAAGENKIAVHDGLLSMDYDELSQAVFHFAGHL
                     SSLGVKSGDRIGLWVDKSCRALAAMLAVTHIGAIYVPIDPANPIRRVEEIRNDCQLSVL
                     ITSAEQLDQCTHDVSIQCRVIVLNEEYYGTADFIASLTCWNEAMKAVPTDSPAVVDYQD
                     VAYMLYTSGSTGTPKGVKITHENALAFINWAKAKLMPSKQDRFANHAPWHFDLSVFDIY
                     VSLLAGASVHLVSELLSYVPKQLIDFIEQQQITVWYSVPTALKLMLEAEPLFAERCKLL
                     TTVIFAGEAFEVKALKVLRAALPQARLYNFYGPTETNVCTYYEIGENVPELLPIGFSAS
                     NSIITIRNNTGEELAQGLRGFICVSGPTVFAGYWGKPAQENQYYNTGDLGYYNEFGELM
                     YNGREDHMVKVKGYRIHLGEVEHAINKHKHVAECVVVLNEDKQLHAHITIKDKAPTLLE
                     LKMHCAKLLPKYMLVDRLQVWSQLPLTRNGKYARQELA"
     aSDomain        5265..6449
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_bmp4_AMP-binding.1"
                     /evalue="6.40E-90"
                     /label="bmp4_AMP-binding.1"
                     /locus_tag="bmp4"
                     /protein_end="411"
                     /protein_start="16"
                     /score="293.5"
                     /tool="antismash"
                     /translation="ENKIAVHDGLLSMDYDELSQAVFHFAGHLSSLGVKSGDRIGLWVD
                     KSCRALAAMLAVTHIGAIYVPIDPANPIRRVEEIRNDCQLSVLITSAEQLDQCTHDVSI
                     QCRVIVLNEEYYGTADFIASLTCWNEAMKAVPTDSPAVVDYQDVAYMLYTSGSTGTPKG
                     VKITHENALAFINWAKAKLMPSKQDRFANHAPWHFDLSVFDIYVSLLAGASVHLVSELL
                     SYVPKQLIDFIEQQQITVWYSVPTALKLMLEAEPLFAERCKLLTTVIFAGEAFEVKALK
                     VLRAALPQARLYNFYGPTETNVCTYYEIGENVPELLPIGFSASNSIITIRNNTGEELAQ
                     GLRGFICVSGPTVFAGYWGKPAQENQYYNTGDLGYYNEFGELMYNGREDHMVKVK"
     CDS_motif       5709..5768
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0001"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="bmp4"
                     /protein_end="184"
                     /protein_start="164"
                     /score="30.1"
                     /tool="antismash"
                     /translation="AYMLYTSGSTGTPKGVKITH"
     CDS_motif       6294..6353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0002"
                     /evalue="1.80E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="bmp4"
                     /protein_end="379"
                     /protein_start="359"
                     /score="13.9"
                     /tool="antismash"
                     /translation="GFICVSGPTVFAGYWGKPAQ"
     CDS_motif       6414..6479
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0003"
                     /evalue="9.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="bmp4"
                     /protein_end="421"
                     /protein_start="399"
                     /score="27.5"
                     /tool="antismash"
                     /translation="YNGREDHMVKVKGYRIHLGEVE"
ORIGIN
        1 tcaagcgtgt aacggcgtat cttgtatagc aataggggtc gctgtattcg ataaccgctg
       61 tagagaaata tttatatttt ctcttaagat tttcttagca gcttggaaat cgcttggaca
      121 attaatgcag gttacagcaa tcaatttgtt agcttttaca taccagtaac tcttgctatc
      181 tgaactgtat gctcgctcta ctacagcgtc atactcttga tatagcccag caatttgtag
      241 tttgcaatca tagatatcag accaaaacca tggcacttgc ctttgtggct gagctgttcc
      301 acaaatactg gctactgcta tttttgcttg ctgaactgca ttaggcacgg attctatggc
      361 agttacctca ccgctgaaag gttctatagc taaggtgcag tcgcccgcgg cataaatatt
      421 aggtgctgca gtttggcatt ggtcgttgac caacactctg ccgcattttg taattaaccc
      481 tgctttatct gccagatctg aattagcatg agcaccaatc ccaacaacaa ccaaatctgc
      541 tggaaaacta ctcccatcat cacagataac agactccact ttgccatttc cagctaatga
      601 tacaactgct ttattggtga ggatcgtcac gcctttggag gcatgtaagg tggttacgta
      661 gctcgctatt ggctcagctg caatacggtt taacacgcgt tcattacgct ctagaatagt
      721 aacttgatgt cccaactttt tgaacgaggc agcggtttct aaacctatat atccaccacc
      781 aatcataacg atattctttt tattttgttc gtaatttacc tgcttagcga tctgctcgat
      841 atcaccaagt gttctgatcg aaaatacgtt tgctaactca gcacctggca gtgttagttt
      901 tcttggagaa gcacctgtac agaggatcag tttatcgtac gataatgtat ctcctgagct
      961 gagcttgatg gtgttttcgt cgggtattac atcgacaaca aaagattcta acttaatatc
     1021 aatatttgct tttgtatagg ctgccggcgg tttaatgtaa agtcgtttca gtggtgattc
     1081 accagtcaag aaggtcttgg aaagaggggg gcgatggtat ggaagatagc tctccgaact
     1141 gaggattaaa atttctcccg tccagttcct tttgcgcagt tcaaaagcgg cctcagcccc
     1201 tgcatggcca cctccaacga tgatacacct tttcatgatt tttccttttt tagtattgag
     1261 actcaggcaa ggtaacgctc aagccatggt gttcttgagt gatttttact tggcaactaa
     1321 ggcgactaaa tgcggttgtg tcgttcacca gttcaagcat ttggctttca ttattatcag
     1381 gctgcgtgac tttacctgac cattgttcag atagataaca atggcatgtt gcgcagcttc
     1441 cggagccacc gcattcaccc tcgatccctt ctactagatt ctctattgca gcctgcataa
     1501 tcgacattcc aggttcaact tcagtatcta ttgttgaacc gtcgtgctgt acaaatgtga
     1561 tttttagcat aataactcca ttttttagtt ttgatattta gttatatata agttacgcat
     1621 tgctggggtt tttcatatag tccgatctaa ctaatttaat agtcctactt agctattttt
     1681 ttattatctt gtttctatat tgtttgtggg gacttgtttt taaattaatg gagattaaag
     1741 tggaaaaaga gctgatcgat tttataaata acgacctttt ggaaggcgcc gcccccgatt
     1801 tagatgaaaa tacgcccttg cttgaattag gtatattaaa ctcattatca atggtgcgtt
     1861 tgcttgcaca tgttgatcaa aagtatggtg caaagatccc tgaaaataat ataacaccag
     1921 tgcattttga gaatataaag acgctttcga tgctgattaa atcactatca gggatcgttg
     1981 aaactgagcg tgcagctgaa gtgtccgagc tagagcgctt ggtttgctta caagagagtt
     2041 atggcattca gcgagagttg atagacaccg gtaacggatt caaacagcac accttacgtg
     2101 ttaaaggtaa aggtccattg tggattatgc ttccagcgct tggcaaccca tcaacatctt
     2161 ggtcttcaac gctacgctca ttacaaggtc gtcacaatgc cattgcgctt gatttagctg
     2221 gatttggact aagccaaagt agcaacgatg cgccttcata tgtagatcat gtggaattta
     2281 cattacagtt tttagaaaca ttagaagagc aagaatgggt acttgtcgct aactccgcgg
     2341 gcagcatgat agcgactgaa atagctcgcc gctatccgga gaaggtgaaa gcgctcgtat
     2401 gtacaggctt tggtttggtg gaagacgttg atagttggtg gggagatctc aagaagatgt
     2461 cttcaaaccc tgagcagttt ttagctgctg catattacca tccaccaaaa atgactcctg
     2521 cgctggaaga cctactaaat gatgtacttt ctagacctgc ttatcactca ttcctcgacg
     2581 agtatgcgcg taaatcaatg gcaaccacgt tcgacggcgt taaggtacca actttattca
     2641 tcgctggtaa tcatgatcag attattcctc cagagtggag cgaaaaagca gctgaaaaac
     2701 tcgaaaatgc aacggtgaca cgcttgtctc gctgtggtca tttctcagcg tcagagcgac
     2761 cagaagagtt tgtttgggta gttgaagatt tcttaaataa ggtggctatg taatgaacgg
     2821 atttacacat tatgacgttg taataattgg aagtgggcct gctgggagcc tatgtggaat
     2881 tgaatgccgt aagaaaggca tgtcggtctt atgtattgaa aaagagcagt ttcctcgttt
     2941 ccacatcggt gagtcgttaa ctggtaatgc tgggcagatc attcgtgact taggccttgc
     3001 agatgcaatg gatgctgctg gatttcctga caaacccggc gtaaacgtta taggctcatt
     3061 atcaaaaaat gagttcttta tcccaattct cgcgccaact tggcaagtgc gtcgcagcga
     3121 ttttgacaat atgatcaaac aaaaggcggt tgaacacggc gttgaatatc aacttggtat
     3181 ggtaactgat gttattcgag aaggtgacaa ggttgttggg gctgtgtata aagccgatgg
     3241 cattgaacat caagtaagat cgaaggtgct agtcgatgcg agtggacaaa acacctttct
     3301 ttcaagaaaa ggcattgcag gaaaacgcca gattgaattc ttctctcagc aaattgcttc
     3361 atttgcgcat tataaagggg tggaaagaga tttaccgccg ttttccacca atacaaccat
     3421 cctatattca aagcaatatc attggtcttg gatcattcct atttctccag atacggacag
     3481 cttaggagtc gttataccga aggatctcta ttataaagag tgcaaaaacc cagatgatgc
     3541 aatcgaatgg ggcatggagc acatcagccc agagctgaag cgacgcttca aaaatgccga
     3601 acgtcaaggt gagtctcagt caatggctga cttttcttac cgaatagaac catttgttgg
     3661 tgatggttgg ctttgcattg gagacgcaca tagattccta gaccctattt tctcctacgg
     3721 tgtttcgttc gcaatgaaag aagggattag agctgctgaa gcgattgaac aggttgttaa
     3781 tggtcaagac tggaaagccc ctttttacgc ttatcgagat tggagcaacg gaggtcaaca
     3841 aatcgcagca gatcttattc gctacttttg gatttacccc attttctttg gctatcaaat
     3901 gcaaaaccct gatcttaggg atgaagtcat acgcttattg ggcggttgtt gttttgattg
     3961 taaggactgg aaagcgccag ctattttcag aaatgcaatc gaagaatacg accgtaaaca
     4021 gatggcaagt taagactgaa gttcaataat taaaaatagg ataagtgggg aatacaaatg
     4081 aattttgaat ggaatgaggc gcagctgtcg ctatttgagc atgctctaag ttattcgtca
     4141 gaattacgat ctacaagcca tcaaccgggc gagtttccac tcgatttatg gaaatcttta
     4201 ggtgacttcg gttattttgg attacctgtt gatagtgaat actcaccttg tggatcggga
     4261 ttggatattt taaccacagt aaaggtactg gagggactcg gacaaggcgg cgcggatacc
     4321 ggcgttttgt ttgccggtgc tgcacatacc tttgcttgtg tcatgccaat ttatgagcat
     4381 ggaagcgaag cgattaagcg ggagttatta cctctactca cctctggaga aaaaatcgcg
     4441 gcgaatgcta tttcggaagc tgaagcaggt tcagacatag caaagttagc aacaacggcg
     4501 agccgagaag gtgattatta catcatcaaa ggcgctaagt cttacgtgac taacggtagt
     4561 gttgctgatt attttatcgc ctatgcgacg actaacgcta agtttggata tctcggacaa
     4621 actgcatttg ttatccccgc tgatttacct ggtatagaag ttggaaatag ctacaaaaaa
     4681 ctgggtttga actctgctca gttgaatcaa gttttctttg atgaggttaa ggtacataag
     4741 cgatatgtgc tcggtgatga gggtcaaggc gctaggatat ttgcagcttc aatggattgg
     4801 gagcgctgtt gtttatttgc gttgtttatt ggcgtgatgc agcgcgattt agatctttgc
     4861 atcgagtatg caaatatgcg caaacaaggt gataagacga tcagtaagtt tcaagctgtt
     4921 tctcaccgta tcgcggatat ggaggttagg ttacaaagtg caaggttgct gctttatttt
     4981 gctgcatggc aaaaatcaaa agaggtagac aatacaaaag cagtggcgac aagcaaatta
     5041 gccatcagcg aagcctttgt acagtctggg ctagatgtga tccgtgtgca tggagcgctt
     5101 ggttatttgg acgaaggtgg agtgaatagc agtattaaag atgcacttgg atctgtgctt
     5161 ttctctggta catcagatat tcaacgtgaa ctaatttgta ataggttagg tttgttatga
     5221 aaaatttgag tgaggttttg ctagctggaa tgtccgcagc cggagaaaac aaaatagccg
     5281 ttcatgatgg tctattaagt atggattacg atgaattatc ccaagctgtc ttccatttcg
     5341 caggccactt gagtagcttg ggggtaaagt ctggtgatcg gattggcctg tgggtggata
     5401 agtcctgtag ggcactagct gcgatgcttg cggttactca tattggcgcg atttatgtac
     5461 cgatagatcc ggcaaaccca ataaggcgtg ttgaagaaat aagaaacgat tgtcaattaa
     5521 gtgtattgat cacctcagct gagcagctag atcaatgcac tcatgatgta tcaattcagt
     5581 gtcgggtgat tgtccttaac gaagaatact atggcactgc cgactttatc gcttcgttaa
     5641 cctgttggaa cgaagctatg aaagctgttc caacagacag ccctgcggta gtcgactatc
     5701 aagatgtcgc ttatatgtta tatacatctg gttcaactgg aacgccgaaa ggagtgaaaa
     5761 tcactcatga gaatgcctta gcatttatta actgggcaaa ggctaaacta atgcccagta
     5821 aacaggatag atttgccaat catgcacctt ggcatttcga tctatctgta tttgatatct
     5881 atgtatcttt attggcgggt gctagcgttc atctcgtgtc tgaattacta agttacgttc
     5941 caaaacagct aattgatttt atagagcagc agcagatcac tgtctggtat tcagtaccta
     6001 ccgctcttaa gttaatgctc gaagctgagc cgcttttcgc ggagcgttgc aagttgctaa
     6061 cgaccgtgat ttttgcagga gaggcctttg aggttaaagc gctaaaagta ttaagggcag
     6121 cattacccca agctcgactt tataactttt atggcccaac agagactaat gtttgcacct
     6181 attatgaaat aggtgagaat gtcccagaat tactacctat tggcttttca gctagcaata
     6241 gcattattac aatcaggaat aatactggtg aagaacttgc gcaaggtttg cgagggttca
     6301 tctgtgtatc aggccctaca gtatttgctg gttattgggg taaaccagct caggaaaacc
     6361 aatattataa cactggtgac ttaggctact acaatgagtt tggtgaacta atgtataacg
     6421 gccgagaaga tcatatggtg aaagtaaagg gctaccgtat tcacttaggt gaggttgagc
     6481 atgcgatcaa taagcataaa catgttgcag aatgtgttgt tgttctcaat gaagacaagc
     6541 agttacacgc gcatattacc attaaagata aagcgccgac gctgttagag ttgaaaatgc
     6601 attgtgctaa actattacca aagtacatgc tggttgatag gcttcaagtt tggtctcaat
     6661 taccgttaac tcgaaatggc aagtatgctc gtcaagagct agcttaa
//
