LOCUS       BGC0001464              6705 bp    DNA     linear   BCT 26-FEB-2016
DEFINITION  Pseudoalteromonas sp. PS5 pyrrole gene cluster, complete sequence.
ACCESSION   BGC0001464
VERSION     BGC0001464
KEYWORDS    .
SOURCE      Pseudoalteromonas sp. PS5
  ORGANISM  Pseudoalteromonas sp. PS5
            Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
            Pseudoalteromonadaceae; Pseudoalteromonas.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 15:37:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6705
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1236)
                     /gene="bmp10"
     CDS             complement(1..1236)
                     /codon_start=1
                     /gene="bmp10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 139.6; E-value: 1.9e-42)"
                     /gene_kind="biosynthetic-additional"
                     /note="ferredoxin reductase"
                     /product="Bmp10"
                     /protein_id="AKJ75105.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.8e-70, bitscore:
                     224.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRCIIVGGGHAGAEAAFELRKKGWQGEIIIVSAESYLPYHRPPI
                     SKTYLTGETPLKRLYIKPAAAYEKANISIKLTAQVVDINALKHTITLDSGELLNYDKLI
                     LCTGCSSRKLTVPGAELGNVFSIRTLDDIEHIARALGSNQPPKHIVMIGGGYIGLETAA
                     SFKKLGHHVTILERGNRILNRIAAEPIAAHITKLHQSQGVSIFTDKSVIALTGEKTVQA
                     VHCSEGESFKADIVVIGIGAEPNTRLANHAGVMTKQGRIEVDQQGKTSVPDIYAAGDCT
                     VGIEPFSGQNTTLESVPSAVQQAKMVAAAICDVPQPQIQVPWFWSDIFDCKLQIAGLYQ
                     GYDTVIERVYNCDSKSYWYVKSNKIIAVTCINCPSDFQAGKKILKENITISLSELKNVV
                     NPIIPNTSPVPA"
     source          1..6705
                     /db_xref="taxon:1437473"
                     /host="Paragoniolithon solubile (crustose coralline algae)"
                     /isolation_source="Carribean"
                     /mol_type="genomic DNA"
                     /organism="Pseudoalteromonas sp. PS5"
                     /strain="PS5"
     misc_feature    1..6705
                     /note="pyrrole gene cluster"
     subregion       1..6705
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6705
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1250..1570)
                     /gene="bmp9"
     CDS             complement(1250..1570)
                     /codon_start=1
                     /gene="bmp9"
                     /note="ferredoxin"
                     /product="Bmp9"
                     /protein_id="AKJ75106.1"
                     /transl_table=11
                     /translation="MLKITFIQHDGETIETEVEPGMSIMQAAIENLVEGIEGECGGSGS
                     CATCHCYLSEQWSDKVTQPDNNESQMLEMVNDTTAFSRLSCQVKITKEHNGLSVTLPES
                     QY"
     gene            1737..2810
                     /gene="bmp1"
     CDS             1737..2810
                     /NRPS_PKS="Domain: PP-binding (12-70). E-value: 6.9e-08.
                     Score: 24.8. Matches aSDomain:
                     nrpspksdomains_bmp1_PP-binding.1"
                     /codon_start=1
                     /gene="bmp1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 70.4;
                     E-value: 3.4e-21)"
                     /gene_kind="biosynthetic-additional"
                     /note="prolyl acyl carrier protein thioesterase didomian"
                     /product="Bmp1"
                     /protein_id="AKJ75107.1"
                     /sec_met_domain="PP-binding (E-value: 7.4e-09, bitscore:
                     24.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.2e-14, bitscore: 42.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-15, bitscore:
                     46.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKELIDFINNDLLEGAAPDLDENTPLLELGILNSLSMVRLLAHV
                     DQRYGAKIPENNITPVHFENIKTLSLLIKSLSGVDNTERNDDVSELERLVCLQESYGIQ
                     RELVDAGNGFKQHTLRVKGKGPLWIMLPALGNPSTSWSSTLRSLQGRHNAVALDLAGFG
                     LSQSQNEAPSYVDHVEFTLQYLETLEEQEWVLVANSAGSMIATEVARRYPDKVKALVCT
                     GFGLVDDVESWWGDLKKMSSNPEQFLAAAYYHPPKMTPALEDLLNDVLSRPAYHSFLDE
                     YARKSMATTFDDVKVPTLFIAGNHDQIIPPEWSEKAAERLENATVTRLSRCGHFSASER
                     PEEFVWVVEDFLNKVAM"
     aSDomain        1773..1946
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_bmp1_PP-binding.1"
                     /evalue="6.90E-08"
                     /label="bmp1_PP-binding.1"
                     /locus_tag="bmp1"
                     /protein_end="70"
                     /protein_start="12"
                     /score="24.8"
                     /tool="antismash"
                     /translation="LLEGAAPDLDENTPLLELGILNSLSMVRLLAHVDQRYGAKIPENN
                     ITPVHFENIKTLS"
     gene            2810..4030
                     /gene="bmp2"
     CDS             2810..4030
                     /codon_start=1
                     /gene="bmp2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 266.8; E-value: 6.5e-81)"
                     /gene_kind="biosynthetic-additional"
                     /note="FADH2-dependent pyrrolyl-S-ACP brominase"
                     /product="Bmp2"
                     /protein_id="AKJ75108.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.8e-10, bitscore:
                     27.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Trp_halogenase (E-value: 1.5e-16,
                     bitscore: 48.8, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGFTHYDVVIIGSGPAGSLCGIECRKKGLSVLCIEKEQFPRFHI
                     GESLTGNAGQIIRDLGLAEDMDAAGFPDKPGVNVIGSLSKNEFFIPILAPTWQVRRSDF
                     DDMIKRKAVEHGVEYKLGMVTDVIKDGEKVVGALYKADGVEHQVRSKVLVDASGQNTFL
                     SRKGVAGKRQIEFFSQQIASFAHYKGVERDLPPFSTNTTILYSKQYHWSWIIPISPDTD
                     SLGVVIPKDLYYKECKNPDDAIAWGMDHISPELKRRFKNAERQGDSQSMADFSYRIEPF
                     VGDGWMCIGDAHRFLDPIFSYGVSFAMKEGIRAAEAIAQVVAGQDWKAPFYAYRDWSNG
                     GQQIAADLIRYFWIYPIFFGYQMQNPDLRDEVIRLLGGCCFDCEGWKAPAIFRNAIEEY
                     DRKQMAS"
     gene            4070..5212
                     /gene="bmp3"
     CDS             4070..5212
                     /codon_start=1
                     /gene="bmp3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 298.6; E-value:
                     1.1e-90)"
                     /gene_kind="biosynthetic-additional"
                     /note="FADH2-dependent prolyl-S-ACP dehydrogenase"
                     /product="Bmp3"
                     /protein_id="AKJ75109.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-18, bitscore:
                     56.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.3e-22, bitscore:
                     67.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.6e-35, bitscore:
                     109.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFEWNEAQLSLFEHALSYSSDLRSTTQKAGEFPFDLWKSLGDFG
                     YFGLPVDSKYSPCGSGLDILTTVKVLEGLGQGGADTGLLFAGAAHTFACVMPIYEHGSE
                     EIKQELLPSLTTGEKIAANAISEAEAGSDIAKLATTARLEGDYYIIKGAKSYVTNGSVA
                     DYFIAYATTNAKYGYLGQTAFVIPANLPGIEVGNSYKKLGLHSAQLNQVFFDDVKVHKK
                     YVLGDEGQGARIFAASMDWERCCLFALFIGVMQRDIDCCIEYANLRKQGDKTISKFQAV
                     SHRIADMEVRLQSARLLLYFAAWQKSQDVDNTKAVAMSKLAISEAFVQSGLDVIRIHGA
                     LGYLDEGGVNGSIKDALGSVLFSGTSDIQRELICNRLGLL"
     gene            5209..6705
                     /gene="bmp4"
     CDS             5209..6705
                     /NRPS_PKS="Domain: AMP-binding (18-411). E-value: 2e-90.
                     Score: 295.1. Matches aSDomain:
                     nrpspksdomains_bmp4_AMP-binding.1"
                     /codon_start=1
                     /gene="bmp4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     300.5; E-value: 3e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="L-proline adenyl transferase"
                     /product="Bmp4"
                     /protein_id="AKJ75110.1"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-103, bitscore:
                     333.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLNEVLLQGKSIAGEHKLAVHDGLLSMDYDELCEAVFHFAGHL
                     ERLGVRSGDRVGLWVDKSCRALAAMLAVTHIGAIYVPIDPANPIRRVEEIRKDCQLSVL
                     ITSAEQLDQCTRDFSIQCQVIVLNEEYYGKAELISSLTCWNDAMQATRLSSPVKVNPQA
                     VAYMLYTSGSTGTPKGVQITHENALAFIGWAKEKLTLSEQDRFANHAPWHFDLSVFDIY
                     VSLLSGASVHLVSELLSYVPKQLIDFIEQQKITVWYSVPTALKLMLEAEPLFGERCERL
                     THVIFAGEAFEIKALKVLRAQLPDTRLYNFYGPTETNVCTYYEVGKHVPDLLPIGYPAS
                     NSVITIRNQQGDKLSQGLRGFICVSGPTVFAGYWGKTAQNSEYYNTGDLGYFNEFGELM
                     YNGREDHMVKVKGYRIHLGEVEHALNQHKHVAECVVVLNEDKQLHAHITIKEKAPTLLE
                     LKMYCAKLLPKYMLIDRLQIWSQLPLTRNGKYARKALMAT"
     aSDomain        5263..6441
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_bmp4_AMP-binding.1"
                     /evalue="2.00E-90"
                     /label="bmp4_AMP-binding.1"
                     /locus_tag="bmp4"
                     /protein_end="411"
                     /protein_start="18"
                     /score="295.1"
                     /tool="antismash"
                     /translation="KLAVHDGLLSMDYDELCEAVFHFAGHLERLGVRSGDRVGLWVDKS
                     CRALAAMLAVTHIGAIYVPIDPANPIRRVEEIRKDCQLSVLITSAEQLDQCTRDFSIQC
                     QVIVLNEEYYGKAELISSLTCWNDAMQATRLSSPVKVNPQAVAYMLYTSGSTGTPKGVQ
                     ITHENALAFIGWAKEKLTLSEQDRFANHAPWHFDLSVFDIYVSLLSGASVHLVSELLSY
                     VPKQLIDFIEQQKITVWYSVPTALKLMLEAEPLFGERCERLTHVIFAGEAFEIKALKVL
                     RAQLPDTRLYNFYGPTETNVCTYYEVGKHVPDLLPIGYPASNSVITIRNQQGDKLSQGL
                     RGFICVSGPTVFAGYWGKTAQNSEYYNTGDLGYFNEFGELMYNGREDHMVKVK"
     CDS_motif       5701..5760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0001"
                     /evalue="2.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="bmp4"
                     /protein_end="184"
                     /protein_start="164"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYMLYTSGSTGTPKGVQITH"
     CDS_motif       6286..6345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0002"
                     /evalue="9.30E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="bmp4"
                     /protein_end="379"
                     /protein_start="359"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GFICVSGPTVFAGYWGKTAQ"
     CDS_motif       6406..6471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_bmp4_0003"
                     /evalue="9.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="bmp4"
                     /protein_end="421"
                     /protein_start="399"
                     /score="27.5"
                     /tool="antismash"
                     /translation="YNGREDHMVKVKGYRIHLGEVE"
ORIGIN
        1 ttaagctggt acaggactgg tgttaggtat aattgggtta actacatttt ttaattctga
       61 taaagagata gtaatatttt cttttagaat tttcttacca gcttgaaagt cagaaggaca
      121 attaatgcaa gtaaccgcaa ttattttatt agactttaca taccagtagc tcttactatc
      181 gcagttatac actctctcaa ttaccgtgtc gtaaccttga tacaaaccag ctatttgtaa
      241 tttacaatca aagatatcag accaaaacca cggcacttgt atttgtggtt gggggacgtc
      301 acatatcgct gctgctacca ttttggcctg ttgcacagca ctaggtacag actctaaagt
      361 ggtattttgg ccactaaagg gctcaatacc aacagtgcaa tcaccagccg cataaatatc
      421 aggcacagag gtttttcctt gctgatcgac ttctattcta ccttgctttg tcatgacgcc
      481 agcatggttt gctaggcgag tgtttggctc tgcacctatg ccgatcacaa cgatatctgc
      541 tttaaaagat tctccttcac tacaatgaac tgcttgcaca gttttctctc cagtcaatgc
      601 gatgacgctt ttgtcggtga aaatactgac gccctgagac tgatgtagtt ttgtgatatg
      661 ggcggcaatg ggttcggctg caatacgatt taaaatgcgg ttgcctctct ccaaaatagt
      721 gacgtgatgg cctagctttt taaaagatgc agcagtttcc aagcctatat acccaccacc
      781 aatcatgacg atatgtttag ggggctggtt actcccaagt gcgcgtgcaa tatgttcgat
      841 gtcgtctaat gttctaattg agaatacatt gccaagttca gcgcctggca cagtcagttt
      901 tcttgaacta caacctgtgc ataggatcaa tttatcataa ttaagtaact cacctgaatc
      961 taaagtgata gtatgtttta gtgcattaat atcaactact tgtgctgtca acttgatact
     1021 gatatttgct ttttcgtagg ccgccgctgg tttaatgtac agccgcttga gaggtgtctc
     1081 tcccgttaaa taagtttttg aaataggagg acgatgatag ggtaaataac tctctgcact
     1141 gactatgatg atttctcctt gccagccttt tttgcgcagc tcaaaagcgg cttctgctcc
     1201 agcatggcca ccaccaacga taatacacct tttcattgtg cttccttttt taatattgag
     1261 actcgggcag cgtaacgctt aatccattat gctctttggt aatttttact tggcaactta
     1321 ggcggctaaa agctgttgta tcgttaacca tttccagcat ttgactttca ttattgtcag
     1381 gttgcgtcac tttatctgac cattgttctg acaaataaca atgacaggtt gcacagcttc
     1441 ccgaaccacc acattctcct tcaatacctt ccactaggtt ttctattgca gcctgcataa
     1501 tagacatacc tggctccact tcggtctcga tggtttcacc gtcatgctga ataaatgtga
     1561 tttttagcat agtaactcca ttattaattt ttaaaataag aactaataaa ttacctgtta
     1621 gtttgttttt tcatatagtc cgatgtaact aattttatag tcccacttgg ctattttatt
     1681 gttttaatat ttctatattg ttttatttga attttaatct aatggagttt taaaaggtgg
     1741 aaaaagaatt aatagacttt ataaataacg atctactcga aggtgctgcg ccagatttgg
     1801 atgaaaatac accattgctt gaacttggta tattaaattc tctatctatg gttcggttac
     1861 ttgcacatgt cgatcaacgt tacggtgcaa aaatccctga gaataatatt acaccagtgc
     1921 attttgaaaa tataaaaaca ctttcactgt taattaaatc gttatctgga gttgataaca
     1981 ctgagcgcaa tgatgatgta tcagagttgg agcgtctagt ctgtctacaa gagagctacg
     2041 ggatccaaag agaacttgtg gatgcaggca atggatttaa acagcatacg ctacgagtca
     2101 aaggcaaagg ccctttgtgg atcatgcttc cggcacttgg taacccttca acctcatggt
     2161 cttcaacatt gcgctctttg caaggtcgtc ataatgcagt ggcattagac ttagcaggat
     2221 ttggcttgag tcagagtcaa aacgaagcac catcatacgt agaccatgta gagtttacct
     2281 tacagtatct agaaacgttg gaagagcagg agtgggtatt agtggccaac tcagctggta
     2341 gcatgatcgc aacagaagta gcacgtcgtt atcctgataa agtcaaagca ctagtttgta
     2401 caggctttgg tttggttgat gatgtcgaga gctggtgggg tgatctgaag aaaatgtcct
     2461 caaacccaga acaattttta gctgctgcgt actaccatcc tccaaaaatg acaccggctc
     2521 tggaagactt acttaatgat gtactttctc gccctgcata tcattctttc ctcgatgaat
     2581 atgcacgtaa atcaatggca actacgtttg atgacgtgaa ggtacctact ttatttattg
     2641 ccggtaacca tgatcaaatt attccccctg agtggagtga aaaagcagcc gagcgccttg
     2701 aaaatgcgac ggttacgcgt ttatcacgtt gtggacactt ttctgcctca gagcgaccag
     2761 aagagtttgt atgggtagtt gaagattttt taaataaggt ggcaatgtaa tgaacggatt
     2821 tacacattat gacgtggtaa ttatcggtag tggacctgct ggtagcttgt gtggaataga
     2881 atgccgtaag aaaggcctat ctgttttgtg tattgagaaa gagcaatttc caaggttcca
     2941 tatcggtgag tcgttaacag gaaatgcagg acaaattatc cgtgacttag gtttagcgga
     3001 ggatatggat gctgcgggct ttcctgacaa accgggcgta aacgtaattg gctcactgtc
     3061 aaaaaatgaa ttcttcatcc ctattcttgc acccacgtgg caagtacgtc gaagtgactt
     3121 tgacgatatg atcaagcgca aagccgttga gcatggagta gagtataagc ttggtatggt
     3181 cactgatgtg attaaagatg gagagaaagt ggtcggtgcg ctttacaaag ccgatggcgt
     3241 cgaacaccaa gttaggtcaa aggtattggt tgatgccagc ggtcagaata ctttcttatc
     3301 gagaaaaggc gtggctggaa aacgacaaat cgagtttttc tcacaacaaa ttgcatcatt
     3361 tgctcactac aaaggtgtgg agcgagactt gccaccattt tcgaccaata ccaccatact
     3421 gtattcaaag cagtatcact ggtcttggat catcccaatt tcaccagata ctgacagctt
     3481 gggtgtggtt attccaaaag atctttatta caaagagtgt aaaaacccag atgatgcgat
     3541 cgcatgggga atggatcata ttagtcctga acttaagcga cgctttaaaa atgctgaacg
     3601 tcaaggtgac tctcagtcaa tggctgattt ctcatacaga attgagccat ttgtaggtga
     3661 cggttggatg tgtatcggtg atgcacatag gttcttagat cccattttct cttacggtgt
     3721 gtcattcgcg atgaaagaag ggatccgagc tgcagaagca attgcacagg ttgttgctgg
     3781 gcaggattgg aaagcgcctt tctatgctta tcgtgattgg agtaatggcg gccagcagat
     3841 tgcagctgat ctgatccgct atttttggat ttaccctatt ttctttggct atcaaatgca
     3901 aaacccagac ctcagagatg aagttatccg tctgctcggt ggctgttgtt ttgattgtga
     3961 agggtggaaa gcgcctgcca tctttagaaa tgcgattgaa gaatacgacc gtaaacaaat
     4021 ggcaagttaa gggaattacc caataacgta taacaagtag gggatacaaa tgaattttga
     4081 atggaatgag gcacagctgt cattatttga gcatgcttta agttattcgt ctgacttaag
     4141 gtctaccacc caaaaagcag gggaatttcc gtttgattta tggaaatctt taggtgattt
     4201 cggttacttt ggattacctg tcgacagtaa atactcacct tgtggttctg gcctagatat
     4261 tttaacgaca gtaaaagtat tagaagggtt agggcaaggc ggtgcagaca cagggttatt
     4321 gtttgcagga gccgcacata cttttgcttg tgtcatgcca atttacgaac atggtagtga
     4381 ggagataaag caagagctat taccttcgct caccacagga gaaaaaattg ctgcaaatgc
     4441 gatatcagaa gcagaagcag gttccgatat cgcgaagtta gcgacaactg cacgtcttga
     4501 gggtgattat tatatcatca aaggagcaaa atcctatgtg accaatggca gtgttgctga
     4561 ctactttatt gcctatgcaa cgaccaatgc taagtacggg tacctcggtc agacagcatt
     4621 tgttatcccc gctaacttac caggaataga ggtaggtaat agttataaaa agctgggttt
     4681 gcactcggct cagctaaatc aggttttttt tgatgatgtg aaagtccaca aaaagtacgt
     4741 attaggtgac gaaggccaag gtgcgaggat atttgcggca tcaatggatt gggaacgctg
     4801 ttgcttattt gcattattta ttggtgtgat gcaacgcgat atagactgct gtattgagta
     4861 tgcaaacttg cgaaagcagg gcgacaagac gataagtaaa tttcaggcgg tatcacaccg
     4921 tatcgccgat atggaagtga gacttcaaag cgcaagatta ttactttatt ttgccgcttg
     4981 gcagaagtcg caagatgtag acaacaccaa agcagtggcc atgagtaaac tcgccatcag
     5041 tgaagctttc gtccaatcag gattagatgt gattagaata catggagcac tgggttatct
     5101 tgatgaaggc ggcgtaaatg gaagcattaa ggatgcgtta gggtcagtac ttttttctgg
     5161 cacgtctgat attcaaagag aattaatatg taacaggctg ggcttactat gaaaaatcta
     5221 aatgaggttt tactccaagg taagtctatt gcaggtgaac acaagttggc tgttcatgat
     5281 ggtttgttaa gcatggatta tgatgagttg tgcgaagcgg tcttccattt tgcaggacat
     5341 ttagagcgtt tgggagtccg ctctggtgac cgtgttggct tatgggtaga caagtcatgc
     5401 cgtgccctcg ctgctatgct tgctgttact catattggcg cgatttacgt gccaatagac
     5461 cctgcaaacc caattcggcg tgttgaggaa ataagaaagg attgccagct tagtgtatta
     5521 attacctcag ctgagcagtt agatcagtgc actcgcgact tttcgattca gtgccaagtt
     5581 attgtgctga atgaagagta ctatggcaaa gctgaactta tttcgtcatt gacttgctgg
     5641 aatgatgcga tgcaagcgac gaggctttca tcccctgtaa aggtcaatcc gcaggccgta
     5701 gcctatatgt tgtatacatc aggttctaca ggtacaccaa aaggtgtcca gataacccat
     5761 gaaaatgcgc tagcatttat tggttgggcg aaagaaaagc tcaccttgag tgagcaagat
     5821 aggtttgcaa accatgctcc atggcatttt gacctttcag tattcgatat ttatgtgtct
     5881 ttactgtctg gtgcaagcgt acatttggtg tctgagttat taagttatgt gccaaagcag
     5941 ttaatcgact tcattgagca gcaaaagata acagtgtggt actcagtgcc tactgcactt
     6001 aagcttatgt tagaagcaga accgctattt ggcgagcgct gtgaacgctt aacacacgtt
     6061 atttttgctg gagaggcgtt cgagataaaa gcattaaaag tattacgagc acaattaccg
     6121 gatacgcgac tatacaactt ttatggccca acagagacta atgtgtgcac ctactatgaa
     6181 gtgggtaagc atgttcctga tcttcttcct attggctatc ccgccagtaa cagcgttatc
     6241 accattagaa accagcaagg agacaaactt tcacaaggtt tacggggctt tatttgtgtt
     6301 tcaggaccta ccgtatttgc cggatactgg ggaaagactg ctcagaatag tgaatactat
     6361 aatacagggg atctaggcta ctttaacgag ttcggtgaac ttatgtacaa cggtcgagaa
     6421 gatcatatgg ttaaagtaaa gggctatcgc attcatttag gtgaagtaga gcatgctttg
     6481 aatcaacaca agcacgtagc agaatgtgtt gtagtactaa atgaagacaa acaattacat
     6541 gcccacatta caatcaagga aaaagcaccg accttgcttg aattgaaaat gtattgtgca
     6601 aagttgttac caaagtacat gttgattgac aggctacaga tctggtcaca attgccatta
     6661 acacgtaacg gcaaatatgc ccgtaaagca ctaatggcga cttaa
//
