Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001466.1:
Cluster 1Polyketide19221
The following clusters are from record BGC0001466.2:
Cluster 2Polyketide11125
The following clusters are from record BGC0001466.3:
Cluster 3Polyketide11363
The following clusters are from record BGC0001466.4:
Cluster 4Polyketide11870
The following clusters are from record BGC0001466.5:
Cluster 5Polyketide11107
The following clusters are from record BGC0001466.6:
Cluster 6Polyketide11704

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank MG837519. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 2. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 2. Biosynthetic class = Polyketide. GenBank MG837518. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 3. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 3. Biosynthetic class = Polyketide. GenBank MG837520. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 4. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 4. Biosynthetic class = Polyketide. GenBank MG837521. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 5. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 5. Biosynthetic class = Polyketide. GenBank MG837522. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274

BGC0001466, wortmanamide A biosynthetic gene cluster from Talaromyces wortmannii. Locus 6. Full MIBiG entry.

Chemical compounds

Compound: Wortmanamide
SMILES string: Copy to clipboard
Exact molecular mass: 366.2635 Da ([M-H]-)
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
MG837519.1
Iterative PKS subtype:
Highly reducing
7
Thioesterase type:
None
Release / cyclization type:
Other

Gene cluster description

wortmanamide A (BGC0001466). Gene Cluster 6. Biosynthetic class = Polyketide. GenBank Not derived from GenBank. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production
MIxS-compliance:Unknown
Comments:The corresponding author for this entry should be both Yang Hai and Prof. Yi Tang, (yitang@ucla.edu)
Contact for this cluster:Yang Hai (UCLA)

Literature references

1. Yang Hai, Yi Tang. (2018) Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi. Journal of the American Chemical Society, vol. 140, no. 4, pp. 1271-1274