LOCUS       BGC0001467             25782 bp    DNA     linear   CON 21-DEC-2022
DEFINITION  Fischerella sp. PCC 9431 Fis9431DRAFT_Scaffold1.2, whole genome
            shotgun sequence.
ACCESSION   BGC0001467
VERSION     BGC0001467
KEYWORDS    .
SOURCE      Fischerella sp. PCC 9431
  ORGANISM  Fischerella sp. PCC 9431
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Hapalosiphonaceae; Fischerella.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            KE650771.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404150
            Source DNA and Organism available from Cheryl A Kerfeld
            (ckerfeld@lbl.gov)
            Source DNA available from Cheryl A Kerfeld (ckerfeld@lbl.gov)
            Organism available from BBB
            Contacts: Cheryl A Kerfeld (ckerfeld@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:37:57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 25782
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..5457)
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (7-435). E-value:
                     2.5e-167. Score: 548.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128775_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (532-834). E-value: 1.9e-107.
                     Score: 350.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128775_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1166-1365). E-value: 6.1e-49.
                     Score: 158.3. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128775_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1457-1525). E-value: 3.5e-27.
                     Score: 86.3. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128775_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1544-1800). E-value:
                     5.8e-36. Score: 116.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128775_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 263.7; E-value:
                     5e-80)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012409810.1"
                     /locus_tag="FIS9431_RS0128775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_035122279.1"
                     /sec_met_domain="hyb_KS (E-value: 2.1e-175, bitscore:
                     572.0, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.7e-108, bitscore:
                     350.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.2e-37, bitscore:
                     116.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-20, bitscore:
                     61.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSQEAIAIIGMSGRFPGAKNVEEFWYNLQNGVESISFFSQEEL
                     ESAGITKELVRHSDYVKANGIIDNIEWFDAAFFGINPKEAAITDPQQRLFLECAWEALE
                     QAGYESETYCGSIGVYAGTGGLNSYYLNNLYPNSDLRKSVGDYQIMIANDSNLLSTRVS
                     YKLNLTGPGLTIQTACSTSLVAISMACRSLLNYECDLALAGGVSLRVPQKTGYLYQEGM
                     ILSPDGHCRAFDAKAQGTVGGSGVGIVVLKRLEEAIADRDYIHAVVKGCGINNDGAKKV
                     GLTAPSVDGQAEVISQALAFAEVEPETITYIEAHGTATPMGDPIEIAALTQVFSHYTQK
                     KSFCALGSVKTNIGHLDSAAGVAGLIKTVCALKHKLIPPTLHFEEPSPEIDFTNSPFYV
                     NTKLSEWKTQGTPRRAGVSSFGVGGTNAHVILEEAPVVQTSEQSRPWQLLMLSAKTDAA
                     LESATVNLVEHLKEHPKLNLADVAYTLSRGRKAFDYRRILVCRTREDAIATLSTHDSQR
                     VLTNFQESIKRRVVFMFSGQGSQYVNMALELYQVEPTFSDEIDRCSRLLKPYLNFDLRN
                     ILYPNSEQVEKAAEQLQQTALAQPALFVIEYALAKLWMSWGVHPTAMIGHSIGEYVAAC
                     LAGVFSLEDALFLVATRGQLMQQLPSGSMLAVPLSEQQVQSLLDEETFHGTSLQIAAIN
                     GLCQCVVSGVTEAVNALLSKLLEQGVECRRLQTSHAFHSGMMEPILEPFTLALKKINLK
                     APNIPYLSNVTGSWITADEATNPSYWTKHLRSCVRFADGLQQLFQQADRILLEVGPGRT
                     LSTLAKQHQEQADGQLVLSSLRHPKDEQSDITFLLTTLGKLWLAGVQIDWSEFYTHERR
                     HRIPLPTYPFERQRYWIEPKKYADTATFNDISLHKKPDIADWFYIPSWKRSILPVKTKF
                     TPSLQEGDITKEKLCWLVFIDACGLGSQLVKQLEQNSQDVTTVMLGEQFTRHGESVYTI
                     NPRKRDDYEALLKELHSLNKAPKTIVHLWSITPNADTSLEIEFFEKSQYLGFYSLLFLA
                     QALGEQNLTDPLQIVVVSNNMQEVTGVEALCPEKATVLGPCRVIPQEYPHITCKNIDIV
                     ISESETWDEGGLLGCILSELAAPPSNLVVAYRETHRWVQTFEPLKLEESVKETLQLRSH
                     GVYLITGGLGGIGLVLAEYLAKTVQARLVLIGRSAFPRKDQWETWLATHDAQDEVSRKI
                     RKLQVIENLGAEVLIKSADVANLEQMLSAITQAYECFGEIHGVIHAAGIVKTEFLRTIQ
                     ETSQVECSEQFQAKVRGLFVLKKVLQGTALDFCLLTSSLSSVLGGLGFVAYSAANLFMD
                     AFAYKCKQTGTPWISTNWDGWKLQEEKKQNIALGHTLAKLVITPTEGVEVFQRLLSISN
                     PVQVVVSTGDLQARVDQWIKRESLGDTKSPKKVDSSSLHLRPNLHNAYVAPKDDVEQTL
                     ANIWQEFLGIKQVGVHDEFFELGGHSLLAVQLMARIEQQFKKNLPLATLFQNSTIERLA
                     TILRQPIDDLDWSALVPIQPNGSKRPFFCVPGAGGNTIYLYNLAHHLGKDQPFYGLQSL
                     GLDGKSKPYTQIEDMAASYIEAIQSIQPSGPYLLGGHSFGGKVAFEMATQLHERGYEVA
                     LLALLDAGGPGYRTNELDIDGIDDAGWLKKIASVVETFYGKSLNVSDETLKVLAPEEQL
                     NYFKEQLQMVNFLPPDVGIKQARGLIQVFKTNSQTASIHMPQAVYPAQITFFRASEEID
                     AVSHANSETLEEELGMGWDKFSAQPLDIHLVPGDHITMLSEPHVQVLAQQLTMCIERSQ
                     ADD"
     protocluster    1..25782
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[5471:17243]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5472..17243
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..25782
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:23185]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..23185
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..25782
                     /SMILES="C(C)C(O)NC(Cc1ccccc1)C(=O)CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="interleaved"
                     /product="T1PKS"
                     /product="NRPS"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /protoclusters="1"
                     /protoclusters="3"
                     /tool="antismash"
     subregion       1..25782
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001467"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25782
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..5457)
                     /locus_tag="FIS9431_RS0128775"
     aSDomain        complement(58..825)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128775_Thioesterase.1
                     "
                     /evalue="5.80E-36"
                     /label="FIS9431_RS0128775_Thioesterase.1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1800"
                     /protein_start="1544"
                     /score="116.9"
                     /tool="antismash"
                     /translation="RPFFCVPGAGGNTIYLYNLAHHLGKDQPFYGLQSLGLDGKSKPYT
                     QIEDMAASYIEAIQSIQPSGPYLLGGHSFGGKVAFEMATQLHERGYEVALLALLDAGGP
                     GYRTNELDIDGIDDAGWLKKIASVVETFYGKSLNVSDETLKVLAPEEQLNYFKEQLQMV
                     NFLPPDVGIKQARGLIQVFKTNSQTASIHMPQAVYPAQITFFRASEEIDAVSHANSETL
                     EEELGMGWDKFSAQPLDIHLVPGDHITMLSEPHV"
     aSModule        complement(58..5436)
                     /complete
                     /domains="nrpspksdomains_FIS9431_RS0128775_PKS_KS.1"
                     /domains="nrpspksdomains_FIS9431_RS0128775_PKS_AT.1"
                     /domains="nrpspksdomains_FIS9431_RS0128775_PKS_KR.1"
                     /domains="nrpspksdomains_FIS9431_RS0128775_PCP.1"
                     /domains="nrpspksdomains_FIS9431_RS0128775_Thioesterase.1"
                     /final_module
                     /locus_tags="FIS9431_RS0128775"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(568..642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0010"
                     /evalue="3.40E-14"
                     /label="NRPS-te1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1630"
                     /protein_start="1605"
                     /score="45.0"
                     /tool="antismash"
                     /translation="QPSGPYLLGGHSFGGKVAFEMATQL"
     aSDomain        complement(883..1086)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128775_PCP.1"
                     /evalue="3.50E-27"
                     /label="FIS9431_RS0128775_PCP.1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1525"
                     /protein_start="1457"
                     /score="86.3"
                     /tool="antismash"
                     /translation="EQTLANIWQEFLGIKQVGVHDEFFELGGHSLLAVQLMARIEQQFK
                     KNLPLATLFQNSTIERLATILRQ"
     aSDomain        complement(1363..1959)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128775_PKS_KR.1"
                     /evalue="6.10E-49"
                     /label="FIS9431_RS0128775_PKS_KR.1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1365"
                     /protein_start="1166"
                     /score="158.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLITGGLGGIGLVLAEYLAKTVQARLVLIGRSAFPRKDQWETW
                     LATHDAQDEVSRKIRKLQVIENLGAEVLIKSADVANLEQMLSAITQAYECFGEIHGVIH
                     AAGIVKTEFLRTIQETSQVECSEQFQAKVRGLFVLKKVLQGTALDFCLLTSSLSSVLGG
                     LGFVAYSAANLFMDAFAYKCKQTGTPWISTNWDGWK"
     CDS_motif       complement(1417..1518)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0009"
                     /evalue="1.90E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1347"
                     /protein_start="1313"
                     /score="39.7"
                     /tool="antismash"
                     /translation="LDFCLLTSSLSSVLGGLGFVAYSAANLFMDAFAY"
     CDS_motif       complement(1858..1956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0008"
                     /evalue="8.90E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="1200"
                     /protein_start="1167"
                     /score="37.6"
                     /tool="antismash"
                     /translation="VYLITGGLGGIGLVLAEYLAKTVQARLVLIGRS"
     aSDomain        complement(2956..3861)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128775_PKS_AT.1"
                     /evalue="1.90E-107"
                     /label="FIS9431_RS0128775_PKS_AT.1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="834"
                     /protein_start="532"
                     /score="350.9"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFSGQGSQYVNMALELYQVEPTFSDEIDRCSRLLKPYLNFDLRNI
                     LYPNSEQVEKAAEQLQQTALAQPALFVIEYALAKLWMSWGVHPTAMIGHSIGEYVAACL
                     AGVFSLEDALFLVATRGQLMQQLPSGSMLAVPLSEQQVQSLLDEETFHGTSLQIAAING
                     LCQCVVSGVTEAVNALLSKLLEQGVECRRLQTSHAFHSGMMEPILEPFTLALKKINLKA
                     PNIPYLSNVTGSWITADEATNPSYWTKHLRSCVRFADGLQQLFQQADRILLEVGPGRTL
                     STLAKQHQEQADGQLVLSSLR"
     CDS_motif       complement(3349..3387)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0007"
                     /evalue="5.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="703"
                     /protein_start="690"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AAINGLCQCVVSG"
     CDS_motif       complement(3487..3609)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0006"
                     /evalue="6.40E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="657"
                     /protein_start="616"
                     /score="89.2"
                     /tool="antismash"
                     /translation="GVHPTAMIGHSIGEYVAACLAGVFSLEDALFLVATRGQLMQ"
     CDS_motif       complement(3613..3672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0005"
                     /evalue="2.60E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="615"
                     /protein_start="595"
                     /score="14.2"
                     /tool="antismash"
                     /translation="ALAQPALFVIEYALAKLWMS"
     protocluster    3656..25782
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[23655:25782]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      23656..25782
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="3"
     cand_cluster    3656..25782
                     /SMILES="C(C)C(O)NC(Cc1ccccc1)C(=O)CC(O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="3"
                     /tool="antismash"
     CDS_motif       complement(3811..3858)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0004"
                     /evalue="1.70E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="549"
                     /protein_start="533"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FSGQGSQYVNMALELY"
     aSDomain        complement(4153..5436)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128775_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.50E-167"
                     /label="FIS9431_RS0128775_PKS_KS.1"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="435"
                     /protein_start="7"
                     /score="548.9"
                     /tool="antismash"
                     /translation="IAIIGMSGRFPGAKNVEEFWYNLQNGVESISFFSQEELESAGITK
                     ELVRHSDYVKANGIIDNIEWFDAAFFGINPKEAAITDPQQRLFLECAWEALEQAGYESE
                     TYCGSIGVYAGTGGLNSYYLNNLYPNSDLRKSVGDYQIMIANDSNLLSTRVSYKLNLTG
                     PGLTIQTACSTSLVAISMACRSLLNYECDLALAGGVSLRVPQKTGYLYQEGMILSPDGH
                     CRAFDAKAQGTVGGSGVGIVVLKRLEEAIADRDYIHAVVKGCGINNDGAKKVGLTAPSV
                     DGQAEVISQALAFAEVEPETITYIEAHGTATPMGDPIEIAALTQVFSHYTQKKSFCALG
                     SVKTNIGHLDSAAGVAGLIKTVCALKHKLIPPTLHFEEPSPEIDFTNSPFYVNTKLSEW
                     KTQGTPRRAGVSSFGVGGTNAHVILEEAP"
     CDS_motif       complement(4375..4419)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0003"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="361"
                     /protein_start="346"
                     /score="11.4"
                     /tool="antismash"
                     /translation="GSVKTNIGHLDSAAG"
     CDS_motif       complement(4480..4527)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0002"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="326"
                     /protein_start="310"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YIEAHGTATPMGDPIE"
     CDS_motif       complement(4903..4950)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128775_0001"
                     /evalue="6.90E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="FIS9431_RS0128775"
                     /protein_end="185"
                     /protein_start="169"
                     /score="15.2"
                     /tool="antismash"
                     /translation="GPGLTIQTACSTSLVA"
     gene            complement(5472..>9950)
                     /locus_tag="FIS9431_RS32925"
                     /pseudo=""
     CDS             complement(5472..>9950)
                     /NRPS_PKS="Domain: Condensation_LCL (10-308). E-value:
                     5.1e-119. Score: 388.6. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS32925_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (473-865). E-value:
                     4.8e-117. Score: 382.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS32925_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (961-1181). E-value: 1e-121. Score:
                     398.2. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS32925_nMT.1"
                     /NRPS_PKS="Domain: PCP (1389-1457). E-value: 3.5e-23.
                     Score: 73.5. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS32925_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     444.6; E-value: 7.8e-135)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017742648.1"
                     /locus_tag="FIS9431_RS32925"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 2e-79, bitscore:
                     255.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-126, bitscore:
                     408.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-15, bitscore:
                     44.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPKSRESGLFPLSFAQQRLWFLDQLMPGNPFYNIPFALRLVGRL
                     DVLALERSLNEIIRRHETLRTCFQTIDAKPTQLIASTFELTLATIDLQDLPQGKRLDEV
                     RKLASIEASRPFDLTQLPLLRVTLLCLTPTEHVLLFVMHHIISDGWSIGVFNRELAVLY
                     EAFVAGKPSPLPELSIQYADFAVWQRQWLQEQTQIQQLRYWQQQLADITVLQLPTDYPR
                     PAVQSFAGATQILKLPQNLKQALIKLSQQHEVTLFMTMLAAFKVLLHRYTGQTDIVVGS
                     PIANRNRSEIEGLIGFFVNSLVLRTNLEGNPSFSDLLTRVREVALGAYAHQDLPFEKLV
                     EELQPERNLSQNQLFQVVFAVQNAPMEELQLKDLQLSRLEFEYKTTRFDLEWHIWEHSQ
                     GLEVMVAYATDLFAPETVERMVGHFQTLLEGIVTNPIGQISQLPLLTEPERQQLLLEWN
                     DTTVDYPIDKCIHQLFEEQAQRTPDAVAVVYENQQLTYDELNCRANQLAHYLRSLGVGP
                     EVLVGICVQRSLEMVVGLLGILKAGGAYVPLDPEYPTSRLSFMLEDATVGVLLTQQHLV
                     QKLPEYGAQRVFLDEVWEQIAQNYQDNPISGVRAFHLANVIYTSGSTGAPKGVMVTHTG
                     LCNLAQAQIQAFGLHNLSRILQFASLSFDASIWEVVMAVGSGATLYLGTKDSLLPGMPL
                     IQLLRDYCITHITLPPSALSVLPVEELPTLQTMIVAGEACSAELIRQWAAGRNFFNAYG
                     PTEATVCATVAKCTDGDKKASIGRPIANTQIYILDSHLQPVPIGVPGELHISGAGLARG
                     YLNRPQLTTEKFIPNPFSTDGHSRLYKTGDLARYLPNGNIEYLGRIDNQVKVRGFRIEL
                     GEIEAILSQHPLVQEGIVVARVDNTTGDKQLVAYLVPVLKNKVLRQQLAQWQSEYVNDW
                     QMLYEQSYGQPQASSDDLTFNISGWNSSYTKQPIPAGEMQEWVDSTVARILSLSPQRVL
                     EIGCGTGLLLSRIANQCQQYWGCDYSSAALHHVEQVCKTVEGLDNVRLLHQMADNFAGI
                     PKGEFDTVVVNSVVQYFPSVEYLLQVLEGAMAALAQEGTLFVGDVRSLPLLEPYHAAVQ
                     LSQAPESRTIEQWQQQVHSSVAAEEELVIDPGFFIALKQRFPQITWVEIQPKRGHSQNE
                     LTQFRYDVTLHVGTHVQATVVPWLNWQLDELSFTQIQNQLHAQQPELLGIRGVPNQRVQ
                     QALQIWEWLENPPGVKTVGQLRQLLTQQPTIGINPEEFCQLGQHLGYTVHLSWWGSSQD
                     GSYDVVFCRNQEQRAIAFWDTETITTKTWTDYTNNPLYGKLVQKLVPQVRSFIQQKLPD
                     YMVPQAFVLLNALPLTPNGKVDRKALPAPDFQQALSANYVVPQTELEQTIARVWQQVLH
                     REKVGIYDNFFDLGGHSLLITQVRSQLQQLLPKKILITDLFQYPTINSLANYLTQLSTE
                     NTAFKQSHQQINQQKQAIHRHKQRRQRQEQK"
     aSDomain        complement(5580..5783)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS32925_PCP.1"
                     /evalue="3.50E-23"
                     /label="FIS9431_RS32925_PCP.1"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="1457"
                     /protein_start="1389"
                     /score="73.5"
                     /tool="antismash"
                     /translation="EQTIARVWQQVLHREKVGIYDNFFDLGGHSLLITQVRSQLQQLLP
                     KKILITDLFQYPTINSLANYLTQ"
     aSModule        complement(5580..9920)
                     /complete
                     /domains="nrpspksdomains_FIS9431_RS32925_Condensation_LCL.1
                     "
                     /domains="nrpspksdomains_FIS9431_RS32925_AMP-binding.1"
                     /domains="nrpspksdomains_FIS9431_RS32925_nMT.1"
                     /domains="nrpspksdomains_FIS9431_RS32925_PCP.1"
                     /locus_tags="FIS9431_RS32925"
                     /monomer_pairings="Phe -> NMe-Phe"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(6408..7067)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS32925_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="1.00E-121"
                     /label="FIS9431_RS32925_nMT.1"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="1181"
                     /protein_start="961"
                     /score="398.2"
                     /tool="antismash"
                     /translation="QPIPAGEMQEWVDSTVARILSLSPQRVLEIGCGTGLLLSRIANQC
                     QQYWGCDYSSAALHHVEQVCKTVEGLDNVRLLHQMADNFAGIPKGEFDTVVVNSVVQYF
                     PSVEYLLQVLEGAMAALAQEGTLFVGDVRSLPLLEPYHAAVQLSQAPESRTIEQWQQQV
                     HSSVAAEEELVIDPGFFIALKQRFPQITWVEIQPKRGHSQNELTQFRYDVTLHVGTH"
     CDS_motif       complement(6942..6977)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0012"
                     /evalue="6.10E+00"
                     /label="C3_starter_134-155"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="1003"
                     /protein_start="991"
                     /score="0.2"
                     /tool="antismash"
                     /translation="GCGTGLLLSRIA"
     CDS_motif       complement(7173..7193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0011"
                     /evalue="1.40E+01"
                     /label="C4_LCL_164-176"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="926"
                     /protein_start="919"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="AQWQSEY"
     CDS_motif       complement(7326..7391)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0010"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="875"
                     /protein_start="853"
                     /score="39.0"
                     /tool="antismash"
                     /translation="YLGRIDNQVKVRGFRIELGEIE"
     aSDomain        complement(7356..8531)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS32925_AMP-binding.1"
                     /evalue="4.80E-117"
                     /label="FIS9431_RS32925_AMP-binding.1"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="865"
                     /protein_start="473"
                     /score="382.9"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FEEQAQRTPDAVAVVYENQQLTYDELNCRANQLAHYLRSLGVGPE
                     VLVGICVQRSLEMVVGLLGILKAGGAYVPLDPEYPTSRLSFMLEDATVGVLLTQQHLVQ
                     KLPEYGAQRVFLDEVWEQIAQNYQDNPISGVRAFHLANVIYTSGSTGAPKGVMVTHTGL
                     CNLAQAQIQAFGLHNLSRILQFASLSFDASIWEVVMAVGSGATLYLGTKDSLLPGMPLI
                     QLLRDYCITHITLPPSALSVLPVEELPTLQTMIVAGEACSAELIRQWAAGRNFFNAYGP
                     TEATVCATVAKCTDGDKKASIGRPIANTQIYILDSHLQPVPIGVPGELHISGAGLARGY
                     LNRPQLTTEKFIPNPFSTDGHSRLYKTGDLARYLPNGNIEYLGRIDNQVKVR"
     CDS_motif       complement(7479..7568)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0009"
                     /evalue="2.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="824"
                     /protein_start="794"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PIGVPGELHISGAGLARGYLNRPQLTTEKF"
     CDS_motif       complement(8052..8111)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0008"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="633"
                     /protein_start="613"
                     /score="29.4"
                     /tool="antismash"
                     /translation="ANVIYTSGSTGAPKGVMVTH"
     CDS_motif       complement(8304..8345)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0007"
                     /evalue="4.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="549"
                     /protein_start="535"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       complement(8871..8987)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0006"
                     /evalue="4.20E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="360"
                     /protein_start="321"
                     /score="77.0"
                     /tool="antismash"
                     /translation="REVALGAYAHQDLPFEKLVEELQPERNLSQNQLFQVVFA"
     aSDomain        complement(9027..9920)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS32925_Condensation_LCL
                     .1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.10E-119"
                     /label="FIS9431_RS32925_Condensation_LCL.1"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="308"
                     /protein_start="10"
                     /score="388.6"
                     /tool="antismash"
                     /translation="FPLSFAQQRLWFLDQLMPGNPFYNIPFALRLVGRLDVLALERSLN
                     EIIRRHETLRTCFQTIDAKPTQLIASTFELTLATIDLQDLPQGKRLDEVRKLASIEASR
                     PFDLTQLPLLRVTLLCLTPTEHVLLFVMHHIISDGWSIGVFNRELAVLYEAFVAGKPSP
                     LPELSIQYADFAVWQRQWLQEQTQIQQLRYWQQQLADITVLQLPTDYPRPAVQSFAGAT
                     QILKLPQNLKQALIKLSQQHEVTLFMTMLAAFKVLLHRYTGQTDIVVGSPIANRNRSEI
                     EGLIGFFVNSLVLRTNL"
     CDS_motif       complement(9036..9125)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0005"
                     /evalue="7.90E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="305"
                     /protein_start="275"
                     /score="56.8"
                     /tool="antismash"
                     /translation="DIVVGSPIANRNRSEIEGLIGFFVNSLVLR"
     CDS_motif       complement(9375..9413)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0004"
                     /evalue="1.70E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="192"
                     /protein_start="179"
                     /score="20.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       complement(9462..9527)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0003"
                     /evalue="3.20E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="163"
                     /protein_start="141"
                     /score="35.6"
                     /tool="antismash"
                     /translation="MHHIISDGWSIGVFNRELAVLY"
     CDS_motif       complement(9747..9860)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0002"
                     /evalue="1.30E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="68"
                     /protein_start="30"
                     /score="62.5"
                     /tool="antismash"
                     /translation="PFYNIPFALRLVGRLDVLALERSLNEIIRRHETLRTCF"
     CDS_motif       complement(9879..9911)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS32925_0001"
                     /evalue="2.60E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="FIS9431_RS32925"
                     /protein_end="24"
                     /protein_start="13"
                     /score="10.3"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     gene            complement(10197..17243)
                     /locus_tag="FIS9431_RS0128785"
     CDS             complement(10197..17243)
                     /NRPS_PKS="Domain: Condensation_LCL (60-363). E-value:
                     7.8e-96. Score: 312.4. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128785_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (533-921). E-value: 1.4e-81.
                     Score: 266.0. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128785_AMP-binding.1"
                     /NRPS_PKS="Domain: CAL_domain (1143-1558). E-value:
                     9.1e-86. Score: 279.6. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128785_CAL_domain.1"
                     /NRPS_PKS="Domain: PKS_KR (1903-2108). E-value: 1.9e-36.
                     Score: 117.6. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128785_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (2249-2317). E-value: 6.5e-27.
                     Score: 85.5. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128785_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     270.7; E-value: 3.3e-82)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.2"
                     /locus_tag="FIS9431_RS0128785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_081656241.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-70, bitscore:
                     225.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.2e-89, bitscore:
                     286.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-18, bitscore:
                     54.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLVEFYQNLLAIGIELWVDGDKLCYEAPEDVLSSELLTEIKQYK
                     EEIINLLQKRTDTAKTHPLSHRQKALWFLYELAPNSAAYNVAYAARLVSNVDIPALRQA
                     ASALIERHSVLRTTYTAQHGEPVQTIQENQEVCFSVQEAANWSQNDFHNWLVSESVRPF
                     DLSNEPVIRFNLLITNTLTDASVAKEVVLLMTVHHIAVDFWSLELLVSELRAFYEAFKT
                     GQEVALPPQTLQYKDYVRWENQMLASQQGERLWNYWREQLAGELPILNLPIDRPRPPVQ
                     TYEGASYPFVLEEKLIHKLLELAKAEGVTLYTIILAAFQVLLLRYTNQEDILIGSPMAG
                     RSLAEFEKIVGYLANPVVLRANLSGNPTFRELLCRVRSCILGALEHQDYPFPVLVERLQ
                     PERDPSRSPLYQVALAWEGSHQGDGQASLMDSDGLIVESITPESKGAAFDLTLTIFDVK
                     EPLRGIWKYNSDLFNAETITRMAKHFQTLLEGIVVNPHQKLSDIPLLSSAERHQLLVEW
                     NDTTVEHPQQLCIHELFEAQVERTPDAVAVVFEDEILTYHELNTKANQLAHYLRSLGVK
                     PEVLVGLCLERSLEQVVGLLGILKAGGAYLPLDPAYPQDRLAFMLEDAKVSVLLTQQYL
                     LGCLPKYKTTVISFNSDTEKIAQQSKENPKSGATPGNLAYVLYSSRRGILVEHCAVGYR
                     LDWLQQTFALSFTDAVLHKAPLAQDTAVWEIFWPLVNGGRLIIAAANSQDDPIYLQHLI
                     ARQKVSIVGFVPSALSSFIESVGEDLVTRLNSLRLVLCSGEPMHQSIALAFRAHFTAEL
                     HNLYSLPESAGEVSYFACEKLGTQQTVPIGYPTYRPIYVLDQYLQPVPIGVKGEIYVGG
                     TGLARGYLQPEEKTALRFVKNPFQQTPDARLFKTGELGRRQNDGTLELLDSSIRQTWIK
                     GYRVELIEVEAALLAAHSVEDAWVLVRQTEIEGPQLVAYVVLKGAFNPKQLQSHLQALL
                     PAYILPCAYVPLSQLPLLATGQVDEQALARLEVINSELVQKWEEQLQKQPSVEQVAVVV
                     TEQVSCLPPLHKSDLLPNCQVAVERSSQAATTAQVGEAFKEKLGSNKLAISHGELLRLP
                     ADAPTTLAGALERAAKHSPTKGIVYIQSDGSEISQFYGDLLLEAQRILMGLRKLGLKPQ
                     DKVIFQLQQNQDFIPAFWGCVLGGFVPVPIAIAPTYSQDNSATRKLENTWLMLGRPLVL
                     TSATQAEAIHSWSKRLKKQNFQLATVDDLRSSEPDRNWYQCQPEDLAILLLTSGSTGIS
                     KAVMQSHRALLSRSAATAQANNFTSLDISLNWFGLDHVGGLVMFHIRDVYLGCQQIHAP
                     TQLVLQDPLLWLDWIELYRATITWAPNFAYGLINDRASEISLRRWDLSQMRFILNAGEA
                     IVAKHARKFLQLLAPKGLPAIAMHPAWGMSETSSAVTFDHNFSLDSTIDEQKFVEVGAP
                     IPGVKVRIIDSNNQVVEENTIGFLQVKGLTVTSGYYQNPEFNQEVFTSDGWFNTGDLGF
                     LRSGRLTITGRQKDIIIINGLNYYSHEIESAVEELSGVEVSYTAAVAVRGVSDHTDKLA
                     IFFSPTIADETEVVNLTKEIRSEVVQKIGVNPDYLVPVEKSAIPKTAIGKIQRQQLRKS
                     FEAGEFNDILKQLDINTGNANTLPDWFYRKIWRPKQAATYTNQLHTGPYLVFLDRLGLG
                     KFICRELNRRNQPYITVEAGLQFFKINRDSYCINPNEPEHYKHLLESLKADDFRIAQIL
                     HLWTYDDYAGEVSSLEALEDAQQQGIYSLLFLIQALAKIQGSEHSVELQVISSHAQFTS
                     SADKIAYEKSTLIGFLKTVPLELSWLQCRHIDLEIQPVEVNAEHIQKELGVGGSDSEIA
                     YRNGRRLCSSIAKVDMLQQQTQEIPFKQGGIYLVTGGLGGIGTYMCQFLIKEYNAKLIT
                     VGRTELPDRTEWSKYLDGETRLGKRIKSYLSIEASGGEFIYKAVDICNLDGLLDVVAQA
                     ESIWNEQLAGIIHLAGEENLEYHWKVMDDHWVTVETQKTFNSMLRPKVHGTWTLYQLIK
                     NNPQAVFISFSSVNSVFGGATFSAYSAANSFLDCCSVYQRYHLHQQTYCFNWAQWDDLG
                     MSQGNPEYARDAALGMGYYIISKEQGLSSLLAALYRNQAHLIIGLDGSNRNIQRYTDSK
                     SYSIQNLTAYFTASNNDSSKASFTELIVRDRFGTKSTCNFVGLQQMPLTDTGEIDREQL
                     KTKDSQRHSGASKWVAPRTEIERQLASIWQQLLSVPQIGIHNNFFELGGHSLLATQLIS
                     RVQDVFQLELPLRSLFENPTVAQLSSVIVQRLIEQTDDEILAQLEELDNDQVKAMLKAE
                     NT"
     aSDomain        complement(10293..10496)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128785_PCP.1"
                     /evalue="6.50E-27"
                     /label="FIS9431_RS0128785_PCP.1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="2317"
                     /protein_start="2249"
                     /score="85.5"
                     /tool="antismash"
                     /translation="ERQLASIWQQLLSVPQIGIHNNFFELGGHSLLATQLISRVQDVFQ
                     LELPLRSLFENPTVAQLSSVIVQ"
     aSModule        complement(10293..13814)
                     /domains="nrpspksdomains_FIS9431_RS0128785_CAL_domain.1"
                     /domains="nrpspksdomains_FIS9431_RS0128785_PKS_KR.1"
                     /domains="nrpspksdomains_FIS9431_RS0128785_PCP.1"
                     /incomplete
                     /locus_tags="FIS9431_RS0128785"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(10920..11534)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128785_PKS_KR.1"
                     /evalue="1.90E-36"
                     /label="FIS9431_RS0128785_PKS_KR.1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="2108"
                     /protein_start="1903"
                     /score="117.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GIYLVTGGLGGIGTYMCQFLIKEYNAKLITVGRTELPDRTEWSKY
                     LDGETRLGKRIKSYLSIEASGGEFIYKAVDICNLDGLLDVVAQAESIWNEQLAGIIHLA
                     GEENLEYHWKVMDDHWVTVETQKTFNSMLRPKVHGTWTLYQLIKNNPQAVFISFSSVNS
                     VFGGATFSAYSAANSFLDCCSVYQRYHLHQQTYCFNWAQWDD"
     CDS_motif       complement(10989..11072)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0014"
                     /evalue="1.80E-09"
                     /label="PKSI-KR_m4"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="2085"
                     /protein_start="2057"
                     /score="30.2"
                     /tool="antismash"
                     /translation="FISFSSVNSVFGGATFSAYSAANSFLDC"
     CDS_motif       complement(11433..11528)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0013"
                     /evalue="5.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1937"
                     /protein_start="1905"
                     /score="28.6"
                     /tool="antismash"
                     /translation="YLVTGGLGGIGTYMCQFLIKEYNAKLITVGRT"
     aSDomain        complement(12570..13814)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128785_CAL_domain.1"
                     /evalue="9.10E-86"
                     /label="FIS9431_RS0128785_CAL_domain.1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1558"
                     /protein_start="1143"
                     /score="279.6"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="YGDLLLEAQRILMGLRKLGLKPQDKVIFQLQQNQDFIPAFWGCVL
                     GGFVPVPIAIAPTYSQDNSATRKLENTWLMLGRPLVLTSATQAEAIHSWSKRLKKQNFQ
                     LATVDDLRSSEPDRNWYQCQPEDLAILLLTSGSTGISKAVMQSHRALLSRSAATAQANN
                     FTSLDISLNWFGLDHVGGLVMFHIRDVYLGCQQIHAPTQLVLQDPLLWLDWIELYRATI
                     TWAPNFAYGLINDRASEISLRRWDLSQMRFILNAGEAIVAKHARKFLQLLAPKGLPAIA
                     MHPAWGMSETSSAVTFDHNFSLDSTIDEQKFVEVGAPIPGVKVRIIDSNNQVVEENTIG
                     FLQVKGLTVTSGYYQNPEFNQEVFTSDGWFNTGDLGFLRSGRLTITGRQKDIIIINGLN
                     YYSHEIESAVEELSGV"
     CDS_motif       complement(12597..12659)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0012"
                     /evalue="8.20E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1549"
                     /protein_start="1528"
                     /score="9.1"
                     /tool="antismash"
                     /translation="TGRQKDIIIINGLNYYSHEIE"
     CDS_motif       complement(12723..12800)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0011"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1507"
                     /protein_start="1481"
                     /score="11.1"
                     /tool="antismash"
                     /translation="IGFLQVKGLTVTSGYYQNPEFNQEVF"
     CDS_motif       complement(13371..13430)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0010"
                     /evalue="2.90E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1291"
                     /protein_start="1271"
                     /score="13.8"
                     /tool="antismash"
                     /translation="AILLLTSGSTGISKAVMQSH"
     CDS_motif       complement(13656..13694)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0009"
                     /evalue="5.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="1196"
                     /protein_start="1183"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="WGCVLGGFVPVPI"
     CDS_motif       complement(14424..14471)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0008"
                     /evalue="1.50E-02"
                     /label="NRPS-A_a8"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="940"
                     /protein_start="924"
                     /score="8.3"
                     /tool="antismash"
                     /translation="RQTWIKGYRVELIEVE"
     aSDomain        complement(14481..15644)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128785_AMP-binding.1"
                     /evalue="1.40E-81"
                     /label="FIS9431_RS0128785_AMP-binding.1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="921"
                     /protein_start="533"
                     /score="266.0"
                     /specificity="substrate consensus: Hiv"
                     /tool="antismash"
                     /translation="FEAQVERTPDAVAVVFEDEILTYHELNTKANQLAHYLRSLGVKPE
                     VLVGLCLERSLEQVVGLLGILKAGGAYLPLDPAYPQDRLAFMLEDAKVSVLLTQQYLLG
                     CLPKYKTTVISFNSDTEKIAQQSKENPKSGATPGNLAYVLYSSRRGILVEHCAVGYRLD
                     WLQQTFALSFTDAVLHKAPLAQDTAVWEIFWPLVNGGRLIIAAANSQDDPIYLQHLIAR
                     QKVSIVGFVPSALSSFIESVGEDLVTRLNSLRLVLCSGEPMHQSIALAFRAHFTAELHN
                     LYSLPESAGEVSYFACEKLGTQQTVPIGYPTYRPIYVLDQYLQPVPIGVKGEIYVGGTG
                     LARGYLQPEEKTALRFVKNPFQQTPDARLFKTGELGRRQNDGTLELLD"
     aSModule        complement(14481..17063)
                     /domains="nrpspksdomains_FIS9431_RS0128785_Condensation_LCL
                     .1"
                     /domains="nrpspksdomains_FIS9431_RS0128785_AMP-binding.1"
                     /incomplete
                     /locus_tags="FIS9431_RS0128785"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(14577..14666)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0007"
                     /evalue="8.30E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="889"
                     /protein_start="859"
                     /score="40.5"
                     /tool="antismash"
                     /translation="PIGVKGEIYVGGTGLARGYLQPEEKTALRF"
     CDS_motif       complement(15417..15458)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0006"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="609"
                     /protein_start="595"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLD"
     CDS_motif       complement(15996..16115)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0005"
                     /evalue="7.50E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="416"
                     /protein_start="376"
                     /score="66.6"
                     /tool="antismash"
                     /translation="RSCILGALEHQDYPFPVLVERLQPERDPSRSPLYQVALAW"
     aSDomain        complement(16155..17063)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128785_Condensation_L
                     CL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.80E-96"
                     /label="FIS9431_RS0128785_Condensation_LCL.1"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="363"
                     /protein_start="60"
                     /score="312.4"
                     /tool="antismash"
                     /translation="THPLSHRQKALWFLYELAPNSAAYNVAYAARLVSNVDIPALRQAA
                     SALIERHSVLRTTYTAQHGEPVQTIQENQEVCFSVQEAANWSQNDFHNWLVSESVRPFD
                     LSNEPVIRFNLLITNTLTDASVAKEVVLLMTVHHIAVDFWSLELLVSELRAFYEAFKTG
                     QEVALPPQTLQYKDYVRWENQMLASQQGERLWNYWREQLAGELPILNLPIDRPRPPVQT
                     YEGASYPFVLEEKLIHKLLELAKAEGVTLYTIILAAFQVLLLRYTNQEDILIGSPMAGR
                     SLAEFEKIVGYLANPVVLRANL"
     CDS_motif       complement(16164..16253)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0004"
                     /evalue="2.10E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="360"
                     /protein_start="330"
                     /score="36.2"
                     /tool="antismash"
                     /translation="DILIGSPMAGRSLAEFEKIVGYLANPVVLR"
     CDS_motif       complement(16506..16544)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0003"
                     /evalue="2.10E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="246"
                     /protein_start="233"
                     /score="10.9"
                     /tool="antismash"
                     /translation="QYKDYVRWENQML"
     CDS_motif       complement(16593..16658)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0002"
                     /evalue="5.30E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="217"
                     /protein_start="195"
                     /score="25.4"
                     /tool="antismash"
                     /translation="VHHIAVDFWSLELLVSELRAFY"
     CDS_motif       complement(16887..17000)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128785_0001"
                     /evalue="3.60E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="FIS9431_RS0128785"
                     /protein_end="119"
                     /protein_start="81"
                     /score="45.1"
                     /tool="antismash"
                     /translation="AAYNVAYAARLVSNVDIPALRQAASALIERHSVLRTTY"
     gene            complement(17240..23185)
                     /locus_tag="FIS9431_RS37445"
     CDS             complement(17240..23185)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (5-424). E-value:
                     3.2e-185. Score: 607.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS37445_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (556-851). E-value: 7e-112.
                     Score: 365.5. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS37445_PKS_AT.1"
                     /NRPS_PKS="Domain: cMT (1154-1366). E-value: 4.6e-104.
                     Score: 340.0. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS37445_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (1596-1774). E-value: 1.4e-64.
                     Score: 209.2. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS37445_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1872-1952). E-value: 9.5e-18.
                     Score: 56.2. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS37445_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 274.9; E-value:
                     2e-83)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308411.1"
                     /locus_tag="FIS9431_RS37445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_035121546.1"
                     /sec_met_domain="hyb_KS (E-value: 1.5e-192, bitscore:
                     628.5, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.2e-113, bitscore:
                     365.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.2e-58, bitscore:
                     186.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-13, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNREPIAIIGIGCRFPKANSPEAFWHLLRDGVDAITEMPPSRWDL
                     NPDTEKLDKTNTRWGGFLEQVDQFDPKFFGISSREAGNIDPQQRLLLEITWEALEDAGQ
                     IPKHLAGTQTGVFIGISTPDFSVLTWGNSGQDIYMTTGTSHSIAANRISYVFNFTGPSV
                     AFDTACSSSLVAVHYACLSLWNQESTLAVAGGVNALLLPKVTANFAKAGFLAPDGRCKT
                     FDARADGYVRGEGGGVVILKPLSQALADCDRIYAVIRGSAVNQDGRSNGLTAPNPQAQS
                     AVLRSAYQLSGISPSQVQYIEAHGTGTSLGDPIEMNALGEVLAEDRAGGNYCAVGSVKT
                     NIGHLEAAAGIAGLIKVALSLKHRQIPPSLHFQKPNPYIPFDKLPLRVQQTLEPWPQGN
                     DLAIAGVSSFGFGGTNAHVVLAEAPLESQKHALERSVDAWRVGSKVQSMPLSEAKGQKK
                     EVIERPVHLLTLSVKSEKALLEMAQRYQEFLLNHSEVLLADVCFTANTGRTHFDYRLAV
                     VAESKVQLQQELSGFTASGETTTVVSGQVKSKKRPKVAFLFTGQGSQYIGMGRQLYETA
                     PIFRQTLDRCDEILRSYLGKSLLTVLYPEAGETSPLDQTAYTQPALFAIEYALSQLWKS
                     WGIVPTAVMGHSLGEYVAATVAGVLSLEDGLKLVAQRSRLMQSLPPEGEMAVVFAAEET
                     IRAITEINNEKISIAAINTPENTVISGERQAVLSICIALEAEGIKTKKLQVSHAFHSPL
                     MEPMLAEFHQIAASITYAAPQIDLISNLTAERLTKEDITPEYWGKHLRSCVRFADSLKT
                     LHALGYEIFVEIGPKPTLLGMGRNCFPEGVGVMLPSLRQGQDDWKLLLQSLGKLYTCGV
                     PVDWSSFDRDYRRELISLPTYPFERQRYWIETFEQRYQQAESLSGENSQSRITNLLEAE
                     NIEQLAQLVLSSGNFSSEQIKLLPELLSVLVREHKQHHIPDFIQDLCYEIVWRSQGSIQ
                     QQSIGDYIPASEEIREILEPQAEQLMSQHYQLYGEALVQLEALSVAYVVTAFQEMGWNF
                     QLGQGFCAAKIVRQLDVVSQHSRLMHRLLEMLVEVGILECKGEQWHVVEVPKIQHPQSQ
                     IGDLLSKYPNAKAELTLLHRCGSNLAQVLQGQCNPLDLLFPEGDLTTAAGLYQDSPGAK
                     VMNTLMQQAVLSVLKDLPSGRTLRVLEIGAGTGGTTSYLLPSFNAQQTEYVFTDLSPLF
                     LAQAKQKFQNFSFVNYQLLDIEKDPQLQGFEQHKYDLIVAANVLHATKDLQVTLQHVQN
                     LLAPQGMLLLLEGTLKSRWLDLIFGLTDGWWRFGDLQLRPNYPLLTTKSWQKLLHNTGF
                     KDVATIVPSYAGNVSQQAVILAQAAKLQETKTEPGSWLIFADNQGIGQELSGLLRSQQQ
                     ACILVYPGTEYKQIAEQEFSINPALPKDFQQLLLEQVACDKTSWRGVVYLWSIDTVSAD
                     ALTVADLEVVSQTGCGGVLSLFQSLISKEFSPPPTLWLVTKGAQRVSIESTLVGVAQSP
                     VWGLGKVIKDEHPEFNCTLVDLDPQGNNNAQSLFAEICSPKPTSGDHIAFRNGQRYVNR
                     LVRSDKIVKKSLQLKADATYLITGGLRGIGLLVAQWMVDHGAKHLVLVGRSRPDSAATE
                     ILRRLEEVGTQVVVIQTDVSQEQEVTSLLNQIKTSMPQLRGIIHSAGVFEDRRLVDHQW
                     QLFAKVFAPKVSGAWNLHTQTQDLPLDFFVLFSSAASILGPAGLANYAAANAFLDTLAD
                     YRRSLSLPGLSINWGPWSMVGMANAVGSRGEVQWATKGIKPIESQQALSILENLLPQDA
                     AQVGVMQVNWSKFLQQFSRSSYPNFVSEIAQQAEKSIPQKQQKVNSPQLLDQIKANSKD
                     QSQSLLITYLGEQIAKALGITTSGLNIDEPLNQMGLDSLMVIELRNRLRAELGVDIPIT
                     KFLDGLSVVGLTKLASEQLFEVKVNSTSKAFVAPTTTLTEKSRIRGEL"
     aSDomain        complement(17330..17569)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS37445_PKS_PP.1"
                     /evalue="9.50E-18"
                     /label="FIS9431_RS37445_PKS_PP.1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1952"
                     /protein_start="1872"
                     /score="56.2"
                     /tool="antismash"
                     /translation="KDQSQSLLITYLGEQIAKALGITTSGLNIDEPLNQMGLDSLMVIE
                     LRNRLRAELGVDIPITKFLDGLSVVGLTKLASEQL"
     aSModule        complement(17330..23170)
                     /complete
                     /domains="nrpspksdomains_FIS9431_RS37445_PKS_KS.1"
                     /domains="nrpspksdomains_FIS9431_RS37445_PKS_AT.1"
                     /domains="nrpspksdomains_FIS9431_RS37445_cMT.1"
                     /domains="nrpspksdomains_FIS9431_RS37445_PKS_KR.1"
                     /domains="nrpspksdomains_FIS9431_RS37445_PKS_PP.1"
                     /locus_tags="FIS9431_RS37445"
                     /monomer_pairings="mal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(17864..18397)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS37445_PKS_KR.1"
                     /evalue="1.40E-64"
                     /label="FIS9431_RS37445_PKS_KR.1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1774"
                     /protein_start="1596"
                     /score="209.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYLITGGLRGIGLLVAQWMVDHGAKHLVLVGRSRPDSAATEILR
                     RLEEVGTQVVVIQTDVSQEQEVTSLLNQIKTSMPQLRGIIHSAGVFEDRRLVDHQWQLF
                     AKVFAPKVSGAWNLHTQTQDLPLDFFVLFSSAASILGPAGLANYAAANAFLDTLADYRR
                     SLSLPGLSINWGPWS"
     CDS_motif       complement(17909..18019)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0012"
                     /evalue="1.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1759"
                     /protein_start="1722"
                     /score="66.2"
                     /tool="antismash"
                     /translation="LDFFVLFSSAASILGPAGLANYAAANAFLDTLADYRR"
     CDS_motif       complement(18041..18070)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0011"
                     /evalue="1.40E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1715"
                     /protein_start="1705"
                     /score="12.0"
                     /tool="antismash"
                     /translation="PKVSGAWNLH"
     CDS_motif       complement(18296..18394)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0010"
                     /evalue="1.60E-18"
                     /label="PKSI-KR_m1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1630"
                     /protein_start="1597"
                     /score="59.1"
                     /tool="antismash"
                     /translation="TYLITGGLRGIGLLVAQWMVDHGAKHLVLVGRS"
     aSDomain        complement(19088..19723)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS37445_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="4.60E-104"
                     /label="FIS9431_RS37445_cMT.1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="1366"
                     /protein_start="1154"
                     /score="340.0"
                     /tool="antismash"
                     /translation="AAGLYQDSPGAKVMNTLMQQAVLSVLKDLPSGRTLRVLEIGAGTG
                     GTTSYLLPSFNAQQTEYVFTDLSPLFLAQAKQKFQNFSFVNYQLLDIEKDPQLQGFEQH
                     KYDLIVAANVLHATKDLQVTLQHVQNLLAPQGMLLLLEGTLKSRWLDLIFGLTDGWWRF
                     GDLQLRPNYPLLTTKSWQKLLHNTGFKDVATIVPSYAGNVSQQAVILAQ"
     aSDomain        complement(20633..21517)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS37445_PKS_AT.1"
                     /evalue="7.00E-112"
                     /label="FIS9431_RS37445_PKS_AT.1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="851"
                     /protein_start="556"
                     /score="365.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYIGMGRQLYETAPIFRQTLDRCDEILRSYLGKSLLTV
                     LYPEAGETSPLDQTAYTQPALFAIEYALSQLWKSWGIVPTAVMGHSLGEYVAATVAGVL
                     SLEDGLKLVAQRSRLMQSLPPEGEMAVVFAAEETIRAITEINNEKISIAAINTPENTVI
                     SGERQAVLSICIALEAEGIKTKKLQVSHAFHSPLMEPMLAEFHQIAASITYAAPQIDLI
                     SNLTAERLTKEDITPEYWGKHLRSCVRFADSLKTLHALGYEIFVEIGPKPTLLGMGRNC
                     FPEGVGVMLPSLRQ"
     CDS_motif       complement(21023..21061)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0009"
                     /evalue="3.90E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="721"
                     /protein_start="708"
                     /score="13.7"
                     /tool="antismash"
                     /translation="AAINTPENTVISG"
     CDS_motif       complement(21155..21277)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0008"
                     /evalue="2.30E-26"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="677"
                     /protein_start="636"
                     /score="84.2"
                     /tool="antismash"
                     /translation="GIVPTAVMGHSLGEYVAATVAGVLSLEDGLKLVAQRSRLMQ"
     CDS_motif       complement(21281..21346)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0007"
                     /evalue="5.30E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="635"
                     /protein_start="613"
                     /score="16.3"
                     /tool="antismash"
                     /translation="QTAYTQPALFAIEYALSQLWKS"
     CDS_motif       complement(21467..21514)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0006"
                     /evalue="1.70E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="573"
                     /protein_start="557"
                     /score="20.3"
                     /tool="antismash"
                     /translation="FTGQGSQYIGMGRQLY"
     CDS_motif       complement(21554..21577)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0005"
                     /evalue="4.90E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="544"
                     /protein_start="536"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="ETTTVVSG"
     aSDomain        complement(21914..23170)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS37445_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.20E-185"
                     /label="FIS9431_RS37445_PKS_KS.1"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="424"
                     /protein_start="5"
                     /score="607.9"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPKANSPEAFWHLLRDGVDAITEMPPSRWDLNPDTE
                     KLDKTNTRWGGFLEQVDQFDPKFFGISSREAGNIDPQQRLLLEITWEALEDAGQIPKHL
                     AGTQTGVFIGISTPDFSVLTWGNSGQDIYMTTGTSHSIAANRISYVFNFTGPSVAFDTA
                     CSSSLVAVHYACLSLWNQESTLAVAGGVNALLLPKVTANFAKAGFLAPDGRCKTFDARA
                     DGYVRGEGGGVVILKPLSQALADCDRIYAVIRGSAVNQDGRSNGLTAPNPQAQSAVLRS
                     AYQLSGISPSQVQYIEAHGTGTSLGDPIEMNALGEVLAEDRAGGNYCAVGSVKTNIGHL
                     EAAAGIAGLIKVALSLKHRQIPPSLHFQKPNPYIPFDKLPLRVQQTLEPWPQGNDLAIA
                     GVSSFGFGGTNAHVVLAEAP"
     CDS_motif       complement(22136..22180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0004"
                     /evalue="3.50E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="350"
                     /protein_start="335"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     CDS_motif       complement(22241..22288)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0003"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="315"
                     /protein_start="299"
                     /score="13.6"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       complement(22481..22519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0002"
                     /evalue="5.00E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="235"
                     /protein_start="222"
                     /score="16.1"
                     /tool="antismash"
                     /translation="FDARADGYVRGEG"
     CDS_motif       complement(22661..22708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS37445_0001"
                     /evalue="7.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="FIS9431_RS37445"
                     /protein_end="175"
                     /protein_start="159"
                     /score="18.1"
                     /tool="antismash"
                     /translation="GPSVAFDTACSSSLVA"
     gene            complement(23656..25782)
                     /locus_tag="FIS9431_RS0128795"
     CDS             complement(23656..25782)
                     /NRPS_PKS="Domain: CAL_domain (46-490). E-value: 3.8e-134.
                     Score: 439.8. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128795_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (625-695). E-value: 7.9e-20. Score:
                     62.9. Matches aSDomain:
                     nrpspksdomains_FIS9431_RS0128795_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     387.6; E-value: 1.2e-117)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017744202.1"
                     /locus_tag="FIS9431_RS0128795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_026723805.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-99, bitscore:
                     322.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-14, bitscore:
                     42.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNNLFSVPTFSEATLVDLLRKRALQQPKQVAYTFLVDGEAQEVS
                     LTYQALDQKARSLAAFLHSMKATGERALLLYPPGLEFIEAFFGCLYAGVTAVPVYPPRR
                     NQRMTRLQAIVKDAEASFALTTTSVLTNIEHSIKQEPELAALHYIATENITNNFAEDWQ
                     PLKINSDTLAFLQYTSGSTGTPKGVMVSHGNLLSNSADLDRGWDHTSESVIVTWLPTFH
                     DMGLIYGAIQPLYKGIPCYMMAPTSFLMRPMRWLEAISRYKATHSGAPNFAYQLCVDKV
                     TSEQLATLDLSSWRMALNGAEPVRADVLKRFAELFKPCGFNLRTFCPGYGLAEATLKVT
                     ATRAKDLPTFYTVQSEALRQNRVVEAQEQEPGSVTLVGCGYTEIDTKIAIVHPESLTTC
                     SPGEVGEIWVSGTTVAQGYWMRNQATEQTFQAYLVDTGEGPFLRTGDLGFLLDGELFIT
                     GRIKDVIIIRGQNYYPQDIELTVQTSHSALRPNCGAAFSMEVEGVERLVIVQEVERSYL
                     RQLNVDQVVRGIRQAVSEQHQLQVYAVVLLKTASIPKTSSGKIQRHACRDGFLNGSLDV
                     VGDWTASLEQNLLQLPQEVEALWEKVHSEDESQADEKSFKPAFTEEAIATWLVSHLALS
                     LRVSPDEIDIQEPFAAYGLDSAVAVSMTGELAQWTGCELEPTLFWRYPNIEAFAQYLAA
                     QCLLLQSITSSVSV"
     aSDomain        complement(23698..23907)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128795_ACP.1"
                     /evalue="7.90E-20"
                     /label="FIS9431_RS0128795_ACP.1"
                     /locus_tag="FIS9431_RS0128795"
                     /protein_end="695"
                     /protein_start="625"
                     /score="62.9"
                     /tool="antismash"
                     /translation="TWLVSHLALSLRVSPDEIDIQEPFAAYGLDSAVAVSMTGELAQWT
                     GCELEPTLFWRYPNIEAFAQYLAAQ"
     aSModule        complement(23698..25644)
                     /domains="nrpspksdomains_FIS9431_RS0128795_CAL_domain.1"
                     /domains="nrpspksdomains_FIS9431_RS0128795_ACP.1"
                     /incomplete
                     /locus_tags="FIS9431_RS0128795"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(24313..25644)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FIS9431_RS0128795_CAL_domain.1"
                     /evalue="3.80E-134"
                     /label="FIS9431_RS0128795_CAL_domain.1"
                     /locus_tag="FIS9431_RS0128795"
                     /protein_end="490"
                     /protein_start="46"
                     /score="439.8"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYQALDQKARSLAAFLHSMKATGERALLLYPPGLEFIEAFFGCLY
                     AGVTAVPVYPPRRNQRMTRLQAIVKDAEASFALTTTSVLTNIEHSIKQEPELAALHYIA
                     TENITNNFAEDWQPLKINSDTLAFLQYTSGSTGTPKGVMVSHGNLLSNSADLDRGWDHT
                     SESVIVTWLPTFHDMGLIYGAIQPLYKGIPCYMMAPTSFLMRPMRWLEAISRYKATHSG
                     APNFAYQLCVDKVTSEQLATLDLSSWRMALNGAEPVRADVLKRFAELFKPCGFNLRTFC
                     PGYGLAEATLKVTATRAKDLPTFYTVQSEALRQNRVVEAQEQEPGSVTLVGCGYTEIDT
                     KIAIVHPESLTTCSPGEVGEIWVSGTTVAQGYWMRNQATEQTFQAYLVDTGEGPFLRTG
                     DLGFLLDGELFITGRIKDVIIIRGQNYYPQDIELTVQTSHSALRP"
     CDS_motif       complement(24349..24411)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128795_0003"
                     /evalue="3.90E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="FIS9431_RS0128795"
                     /protein_end="478"
                     /protein_start="457"
                     /score="19.4"
                     /tool="antismash"
                     /translation="TGRIKDVIIIRGQNYYPQDIE"
     CDS_motif       complement(24496..24582)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128795_0002"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="FIS9431_RS0128795"
                     /protein_end="429"
                     /protein_start="400"
                     /score="30.3"
                     /tool="antismash"
                     /translation="PGEVGEIWVSGTTVAQGYWMRNQATEQTF"
     CDS_motif       complement(25207..25266)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FIS9431_RS0128795_0001"
                     /evalue="7.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="FIS9431_RS0128795"
                     /protein_end="192"
                     /protein_start="172"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGTPKGVMVSH"
ORIGIN
        1 tcaatcatct gcctgtgacc gttcaatgca cattgtcaac tgttgtgcta aaacctgaac
       61 gtgaggttca ctaagcattg taatatggtc acctggaaca aggtggatat ccagaggttg
      121 agcagaaaac ttgtcccagc ccattcctag ttcttcttct aaagtttcag agtttgcatg
      181 actaacagca tcaatctcct cgctagcccg gaaaaacgta atttgagcag gataaactgc
      241 ttgtggcata tgaatggaag cagtttggga gttagttttg aaaacctgaa ttaaaccgcg
      301 agcttgctta attccaacat cgggaggcag gaaattgacc atttgtaact gctctttgaa
      361 atagttcagt tgctcctctg gagcaagaac tttgagagtt tcgtcagata cgtttaaact
      421 ctttccgtag aacgtttcaa ctacgctggc aatcttcttc agccatccag catcatcaat
      481 gccatcaata tctagttcat ttgttctata accaggtcca ccagcatcca aaagggcaag
      541 cagagcgact tcatatcccc gctcgtgtaa ttgagtcgcc atctcaaaag ctaccttacc
      601 accaaaggaa tgaccaccta acaggtatgg tccagagggt tgaatggact gtattgcttc
      661 aatgtaagaa gctgccatat cctcgatttg tgtgtatggt tttgatttcc cgtcaagacc
      721 gagtgattgt agcccataaa atggttgatc tttacctaaa tgatgtgcca ggttgtacaa
      781 gtagatggta tttccacccg ctccaggcac gcagaagaaa ggtcgcttag aaccattagg
      841 ctgaataggt actaaagcgg accaatctaa atcatctatc ggctggcgaa gaatagttgc
      901 taatcgttca attgttgagt tttggaagag tgtcgccaag gggagatttt tcttgaattg
      961 ctgctcaatc cgtgccatga gttgcacggc taaaagagaa tgtcctccca actcaaagaa
     1021 ctcatcatgg actcctacct gcttaattcc aagaaattct tgccagatat ttgcgagggt
     1081 ttgctcgacg tcatctttag gagcaacata ggcattgtgc aaattcggtc ttaagtggag
     1141 tgaggatgag tctactttct ttggagattt tgtatctcct aaagactctc gtttaatcca
     1201 ttgatcgact ctggcttgga ggtccccagt cgaaacaacc acctgaacag ggttactaat
     1261 agataaaaga cgttgaaaca cttctacacc ttcagtaggt gttatgacca atttagccaa
     1321 agtgtgtcca agagctatat tttgtttttt ttcttcctga agtttccaac catcccagtt
     1381 agtactgatc caaggcgtgc ctgtttgctt acatttgtaa gcaaaggcat ccatgaaaag
     1441 gttggctgcg gaataagcaa caaaccctaa tccccctaaa acagatgata gggaagatgt
     1501 cagcaagcaa aaatcaagcg ctgtgccttg taaaactttt ttcaatacga atagcccgcg
     1561 tactttggct tgaaattgct cagagcactc aacttggctt gtttcctgaa tggttcttaa
     1621 gaactctgtt ttaacaattc cggctgcatg gatgacacca tgaatttcgc caaagcactc
     1681 gtaggcttgc gtaattgctg agagcatctg ttccagatta gcaacatctg cgctctttat
     1741 tagaacttct gctcccaggt tctcaatcac ttgtagtttt cgtatcttgc ggcttacctc
     1801 atcctgagca tcatgggttg ctaaccatgt ttcccactgg tcttttcttg gaaaagctga
     1861 acgccctatc aatactagtc ttgcctgcac agtctttgct agatactctg caagcacaag
     1921 accaatacct cctaacccac ctgtgatcaa gtatacaccg tgcgatcgta actggagtgt
     1981 ttctttgact gactcttcta atttaagtgg ctcaaaagtt tgcacccatc gatgagtctc
     2041 acggtaggcc acaactaggt tagacggggg agcagcgagt tctgataaaa tgcaacccag
     2101 caatccccct tcgtcccaag tttctgattc agaaataaca atatcaatgt ttttgcacgt
     2161 aatgtgcggg tactcctgtg gaataactct acaaggtcct agtactgttg ctttctctgg
     2221 gcaaagcgcc tcaacgcctg tcacttcctg catattgttt gacacaacta caatttgaag
     2281 aggatctgtc aaattctgtt ctccaagtgc ctgtgccaga aacagcagac tatagaagcc
     2341 caagtattga gacttttcga aaaactctat ttctaaagag gtatcagcat tcggtgtaat
     2401 actccataaa tgcacaattg tttttggggc tttgtttagt gagtgaagtt ccttgagcaa
     2461 ggcctcatag tcatcacgtt ttcgaggatt aattgtatat acactctccc cgtgcctggt
     2521 aaactgctct cctagcatca cggtagttac atcttggctg ttttgctcca gttgtttcac
     2581 tagctgagat cctaacccac acgcatcaat aaacaccaac cagcataatt tttcctttgt
     2641 tatatctccc tcttgtagag atggggtgaa ttttgtcttt acagggagaa tggatcgttt
     2701 ccaggaagga atatagaacc agtctgcaat atccggcttt ttgtgtaatg agatatcatt
     2761 gaaggtagct gtgtctgcat attttttggg ttcaatccag taacgctgac gctcaaaagg
     2821 atacgttggc aagggaatac ggtggcgtcg ttcatgagta taaaattctg accaatctat
     2881 ctgcactcct gcaagccaga gtttacccaa ggtagtgagc aagaaagtta tatccgactg
     2941 ctcatcttta ggatggcgta acgaagatag tacaagctgt ccatctgctt gctcttgatg
     3001 ttgttttgct aatgtactca acgtccgacc tggacctacc tccaacaaga tccgatctgc
     3061 ttgttgaaac aactgttgca agccatctgc aaagcgcaca catgagcgta aatgctttgt
     3121 ccaatagctg ggatttgttg cttcgtccgc tgtaatccaa ctgccagtaa cgttggacaa
     3181 gtaaggaata ttgggtgctt tgaggttgat ttttttcagc gcaagagtaa atggctccaa
     3241 gattggctcc atcattccag aatggaaggc atgagaggtc tgcaggcggc gacactccac
     3301 accttgttct agtagcttcg agagcaaggc attcactgct tcagtgacac ccgaaactac
     3361 gcattggcat agtccgttaa tcgcagcaat ttgtagagat gttccatgaa acgtctcctc
     3421 atctaaaaga gattgcacct gctgttctga tagtggaacc gcaagcattg acccagaggg
     3481 caattgctgc atcaattgac ctcgtgtagc cactaagaac aaggcatctt ctaaggagaa
     3541 aacaccagcc aaacaagctg caacatattc acctatgctg tgaccaatca ttgctgttgg
     3601 atgcactccc caggacatcc ataacttagc tagggcgtat tcaattacaa acagcgctgg
     3661 ttgtgctaaa gcagtctgtt gcagttgctc tgctgctttt tcaacctgct cagagttggg
     3721 atacaatatg ttacgcaggt caaaattaag gtaaggtttg agaagtcgag agcatctatc
     3781 aatttcatca gaaaatgttg gctcaacttg gtaaagttcc aacgccatat tcacgtactg
     3841 cgatccctgt ccagaaaaca taaatacgac tcttcgcttt atggattctt gaaagttggt
     3901 caaaacccgt tgtgagtcat gggttgagag tgtagcgatc gcatcttctc gagttcgaca
     3961 aaccaatatc cgtcgatagt caaaagcctt tcgacctcta cttaaggtgt aagcaacatc
     4021 agccaggtta agcttgggat gctcctttaa gtgctccact agattcaccg ttgcactttc
     4081 aagtgcagca tcggtttttg ctgagagcat gagcaattgc caaggtcgtg attgttcgga
     4141 ggtttgaaca accggagctt cttcaagaat aacatgggca tttgtaccac caacgccaaa
     4201 ggaacttact cctgcacggc gtggagttcc ttgagttttc cattcagaaa gtttggtgtt
     4261 gacataaaat gggctgttgg taaaatcaat ttctggtgat ggttcctcaa aatgtagggt
     4321 cggtggtatt aacttatgtt tgagcgcaca aacagtttta atcaaaccag caacaccggc
     4381 tgctgaatcg agatgtccga tgttggtttt tactgaaccc agagcacaga aacttttctt
     4441 ttgagtgtag tgtgagaaaa cctgtgtgag agccgcaatt tctatggggt cccccatagg
     4501 ggttgctgtt ccgtgagctt ctatataagt gatggtttcc ggttcaactt cagcaaaagc
     4561 cagagcctgt gaaatcactt ccgcttgacc atccacactc ggtgcggtta agccaacttt
     4621 ctttgcaccg tcattgttaa tcccacagcc tttgacgaca gcatgaatgt agtctctatc
     4681 tgcgatcgcc tcctctaatc tttttagcac cacaattccg acaccgctac cacccacagt
     4741 tccttgtgct ttcgcatcaa aggcgcgaca gtgaccatca ggagaaagaa tcatgccttc
     4801 ttggtataaa tatcccgttt tttgagggac tcgcagtgaa acaccacctg ccaaagccag
     4861 atcgcattca taatttaaca agcttcggca agccatagaa attgcaacta atgaagtcga
     4921 gcaagccgtt tgaatcgtca gacctggtcc tgtcagattt aacttgtaag aaactcgtgt
     4981 tgataagaga ttgctatcat tagcaatcat tatttgataa tctccaacag attttcttaa
     5041 gtcagaatta ggataaaggt tattcaagta gtagctgttg agtccccctg ttcctgcata
     5101 aactcctatg gaaccacagt aggtttctga ctcataacct gcttgctcta atgcttccca
     5161 tgcacattct aaaaaaaggc gctgttgtgg gtctgtgatt gctgcttctt ttggatttat
     5221 gccaaagaat gctgcatcaa accattcaat gttgtcaatg ataccgttgg ctttgacata
     5281 atcagagtgc cgaaccaatt cttttgtaat acctgctgat tctagttcct cttgagaaaa
     5341 gaacgatata gattctacac cattttgtag gttgtaccaa aactcttcta cattttttgc
     5401 cccaggaaat cgacctgaca tgccaataat agcaatggct tcttgagaat cggacatttc
     5461 aaatttctcc actatttttg ctcctgacgt tgcctgcgtt gcttatgccg atgaatggcc
     5521 tgtttttgct gattaatttg ttggtggctt tgcttaaatg cagtattttc tgttgacaac
     5581 tgagttaaat aattcgctaa agaattgatg gtgggatact gaaacagatc cgttattaat
     5641 atctttttgg gaagcagttg ttgtagctgg ctacgaacct gagttatcag taatgaatga
     5701 cctcctaaat caaaaaagtt gtcatatatt cccacttttt ctcggtgtaa tacctgctgc
     5761 caaactctag caattgtttg ttctaattca gtttggggta ccacataatt tgctgataac
     5821 gcttgttgaa aatctggtgc gggcaatgct ttacggtcta ctttgccatt gggtgtcaag
     5881 ggcagggcat ttaggagaac aaaagcttgc ggcaccatgt aatcgggtag cttttgttgg
     5941 ataaaggagc gtacttgcgg cactagcttc tggactaact tgccgtatag gggattgtta
     6001 gtgtagtcag tccaggtttt ggtagtgatt gtctcagtat cccagaaggc gatcgccctt
     6061 tgttcttgat tgcggcagaa caccacatca taagaaccat cttgactact cccccaccaa
     6121 ctcaagtgga ctgtgtaacc gagatgctgc cccaattggc aaaactcttc gggattaatc
     6181 ccaattgttg gctgttgtgt cagcaattgc cgtagttgcc ccactgtctt cacaccaggg
     6241 ggattttcta accattccca aatctgtaat gcttgctgca cccgttgatt aggcacgccc
     6301 ctgattccca aaagttctgg ctgttgggcg tgcagttgat tttgaatttg tgtgaacgaa
     6361 agctcatcta gttgccagtt taaccaagga actaccgttg cttggacatg agtacctaca
     6421 tggagggtaa catcatagcg gaattgagtt aactcatttt gagaatgacc gcgtttgggc
     6481 tgaatctcta cccaagtaat ctggggaaaa cgttgtttca gggcgatgaa gaaaccagga
     6541 tcaatgacca attcttcttc ggcggctaca ctagagtgta cctgctgttg ccattgctca
     6601 atagttctgg actcaggggc ttgggacaac tgcacggctg catggtatgg ctccaagaga
     6661 ggcaagctgc ggacatcccc cacaaatagc gtaccctctt gggcgagcgc cgccattgct
     6721 ccttcaagaa cctgcaacaa atactcaacg ctggggaagt attgcactac tgagttgaca
     6781 actacagtat cgaactctcc tttgggaata cctgcaaagt tatccgccat ttggtgtagc
     6841 aaccgcacat tgtctagacc ttccaccgtt ttacatacct gctcaacgtg gtgtagggcg
     6901 gcgctggaat aatcacatcc ccaatactgt tgacattgat tagcgatacg ggataataat
     6961 aaccccgtgc cacaaccaat ttctaatact cgctgtggcg acagagacag aattcgcgct
     7021 actgtactat cgacccactc ctgcatttcc ccagctggga ttggttgctt agtgtaacta
     7081 ctgttccaac cactaatatt gaacgtgaga tcatctgacg atgcttgagg ttgcccatag
     7141 ctttgttcat aaagcatttg ccagtcatta acgtactcac tctgccattg agccagctgc
     7201 tggcgtaata ctttgttttt gagtacaggt actaagtaag ccaccagctg tttatcgcca
     7261 gtggtgttgt caactctggc gacgacgata ccttcttgta ccaagggatg ttggctcaaa
     7321 attgcttcaa tttcgcctaa ctcgatccgg aagccgcgca ccttgacttg attgtcgatg
     7381 cgtcccaggt attctatatt gccatttggt aaatagcgtg ctaagtcccc agttttgtag
     7441 aggcgggaat gcccgtcagt actaaagggg ttggggatga atttttcagt tgtcaactgg
     7501 gggcggttga ggtagcctct tgctaaccca gcaccactga tgtgcaactc tcctggtaca
     7561 ccgatgggga ctggttgtaa gtgcgagtct aaaatgtaaa tttgcgtgtt ggctataggg
     7621 cgaccgatag aggctttctt gtcaccatcg gtgcattttg ctacagtggc acagacagta
     7681 gcttctgttg gtccgtaggc gttgaagaag tttctgccag cagcccattg tcttatcagt
     7741 tcagcagaac aagcttctcc tgccacaatc attgtttgca gtgtggggag ttcctcaaca
     7801 ggcagaacgg agagcgccga tggtggtagc gtgatatgcg taatacaata atcgcgcaat
     7861 agctgaatta acggcatacc aggcagtaga gagtcttttg ttcccaggta aagtgttgct
     7921 cctgacccaa cagccatcac aacttcccag atagaagcat caaaactgag ggaggcaaac
     7981 tggagaatac ggcttaagtt gtgcaagcca aaagcctgaa tctgagcttg agccaagttg
     8041 caaagcccgg tatgcgtaac catcacacct ttgggtgcac ctgtagatcc actcgtgtaa
     8101 atcacattag ccagatgaaa agctctcacc ccactgatgg ggttatcctg gtagttttgg
     8161 gcaatttgtt cccatacttc atccaaaaag actcgctgcg ccccgtactc aggtagcttc
     8221 tggactaagt gctgttgggt caacagcact cctacagtag catcttcgag cataaagctc
     8281 aaccgactgg tgggatactc agggtcaagc ggcacgtaag ccccacccgc cttgagaatg
     8341 cccaatagcc ccaccaccat ttcaagtgat cgttgcacac aaatgccgac cagcacttca
     8401 ggacctacac ccaatgagcg caagtagtgc gccaattggt tagcgcgaca attcaactca
     8461 tcgtaggtca gttgttgatt ttcatacacc actgccaccg catctggggt gcgttgtgcc
     8521 tgctcctcaa ataactgatg gatacactta tcaataggat agtctacagt agtatcattc
     8581 cactccagga gtaactgctg tcgctctggc tctgtaagca ggggcaattg ggaaatctgc
     8641 ccaatgggat tcgtaacaat cccctcaagc aatgtctgga aatgacccac catccgctca
     8701 acagtctctg gagcaaacaa atccgtcgcg taagctacca tgacctcaag accttgggaa
     8761 tgctcccata tgtgccattc tagatcaaag cgcgtcgttt tgtactcgaa ctctaaccgt
     8821 gacaattgca gatctttgag ttgtaactcc tccataggtg cattttgtac ggcaaacacc
     8881 acctgaaaca attgattttg actgagattg cgctccggct gcagctcctc caccagcttt
     8941 tcaaaaggca aatcttgatg agcataggct cctagagcta cttctcgtac cctagtgagc
     9001 aaatcactaa agctgggatt gccctccagg tttgtacgca gcaccagaga gttgacaaaa
     9061 aagccaatta gtccctcaat ctcagatcgg ttgcgattgg cgatgggaga ccccaccaca
     9121 atatctgttt gacctgtgta gcgatgcaat aatactttga aagcagcaag catggtcatg
     9181 aaaagagtta cttcatgttg ctggctgagt tttattagcg cctgtttcag attctggggg
     9241 agtttgagaa tttgtgtggc accagcaaaa gactgtactg ctggtcgggg atagtcagtg
     9301 ggtaactgta gtactgtaat atctgctaat tgttgctgcc agtaccgtag ttgttggatt
     9361 tgtgtttgtt cttgtaacca ctgccgctgc cacacagcaa aatcagcata ttgaattgaa
     9421 agttctggta agggtgaagg cttgccagcg acaaaggctt cgtaaagtac agctagttct
     9481 cgattgaaca ctccgattga ccagccatct gatatgatgt ggtgcataac aaacagcagc
     9541 acatgttcgg tgggtgtcag gcacaatagc gtcacgcgca gcaagggtag ctgagttagg
     9601 tcaaacggtc gtgatgcttc aatgcttgcc agtttgcgaa cttcatctaa gcgctttcct
     9661 tgaggcagat cttgcaggtc gatagtggca agtgttaact caaaagtgga cgcaattagc
     9721 tgcgtcggct ttgcatcaat tgtctggaag caagtacgca gggtttcgtg acggcggatg
     9781 atttcattaa ggctgcgctc aagcgccaac acatctagcc taccaacaag acgcaatgca
     9841 aaaggtatgt tgtagaaagg attaccaggc atcagctggt ctaggaacca caagcgttgt
     9901 tgggcaaagg atagagggaa taagccactt tctctacttt tcgggcttat ttcttttttt
     9961 tgtaagtttt cctgtttttt gttacgtagt tttaagagaa gttctaactt ttctggagac
    10021 aaatctgcgg tttttttaga gatattgctc aagtgagtat cctctttgaa ttaaaagatt
    10081 aagtattttg gtagttttaa aaagttttcg ctacctttga aaggttaatt tggaaatgtc
    10141 tttgaatcag gagtttcaaa agatagccgt tcaatgtggc gaaaaactta agagactcaa
    10201 gtattttcgg cttttagcat tgcttttact tggtcattgt caagttcttc taactgagcc
    10261 aagatctcgt catctgtttg ctcaattagt ctctgtacta tcacactaga cagttgtgcc
    10321 accgttggat tctcaaacaa gctacgcaac ggcaactcca actggaacac atcttgcacc
    10381 ctggagatca actgagtcgc cagcagcgaa tgtcctccca actcaaagaa attattatgt
    10441 atgcctattt gtgggacact caacagttgt tgccagatac tagcaagctg acgttcaatc
    10501 tccgtccgtg gcgctaccca cttacttgcc ccagagtgtc tttggctatc cttcgttttc
    10561 agttgctctc ggtcaatttc ccctgtgtct gttaaaggca tctgttgcag cccgacaaaa
    10621 ttgcaagtgc tcttagtacc aaagcgatcg cgcactatca attccgtgaa gctagctttt
    10681 gaggaatcgt tgttgctcgc agtaaaataa gcagttaaat tctgtataga ataagacttg
    10741 ctgtccgtgt atcgttgaat gtttcgattg ctaccatcta aacctataat caggtgtgcc
    10801 tgattgcgat acaaagctgc cagcaaagaa cttaatcctt gctcttttga gatgatatag
    10861 tagcccatac ccaaagcagc atcgcgggca tattcgggat ttccctgact catgcccaag
    10921 tcatcccact gcgcccagtt aaaacagtaa gtctgttgat gtaaatgata tcgctgatac
    10981 acagaacaac agtctagaaa actattagca gcagaatatg cactaaaggt agctcctcca
    11041 aatacactat ttactgaaga gaaagaaata aatactgctt gagggttgtt cttgatgagt
    11101 tggtagagcg tccacgtgcc atgaaccttg ggtcgcaaca tagaattgaa agtcttttga
    11161 gtttccactg ttacccagtg gtcgtccatg actttccagt ggtactctaa attctcctcc
    11221 cctgctaaat gaataatccc tgctagttgt tcattccaaa ttgactcggc ttgggcaaca
    11281 acatcaagca aaccatcaag gttgcatata tcaacggctt tgtaaataaa ctcaccacct
    11341 gatgcttcaa ttgagaggta acttttgata cgcttaccca aacgtgtttc tccgtcaaga
    11401 tactttgacc attcagttct atctggcaac tctgttcgac ctacagtaat gagttttgca
    11461 ttatactcct taatcaaaaa ttggcacata tatgtaccta ttccacccaa tccccctgtc
    11521 accagataaa ttccaccttg cttaaaggga atctcctggg tttgttgctg caacatatct
    11581 actttggcaa tagatgagca aagacgccga ccattacgat aggcaatttc cgaatcgctt
    11641 cccccaacgc ccagttcttt ctgaatatgc tctgcattca cctccacagg ctgaatttct
    11701 aaatcgatat ggcgacattg caaccaagat aactccagag gaactgtctt taaaaatcct
    11761 ataagcgtag atttttcata agcaatcttg tcagcgcttg aggtgaattg tgcatggcta
    11821 gaaattactt gcaactcaac cgaatgctca gaaccttgga tttttgccag agcttgtatc
    11881 aaaaacagca gactgtagat tccttgttgt tgagcatctt cgagagcctc taagctggaa
    11941 acttccccag cataatcgtc ataagtccat aaatgaagaa tttgggcgat acggaaatca
    12001 tcggctttta aggactctaa caggtgctta tagtgctcgg gttcattcgg attaatgcaa
    12061 taggaatcgc gatttatctt gaagaattgt aaccccgctt caacagtgat gtagggttga
    12121 tttcgccgat tgagttctct acagataaat tttcctaatc ctaagcgatc taggaaaacc
    12181 aggtaaggac ctgtatgaag ctgatttgtg taggttgctg cttgtttggg acgccaaatc
    12241 ttgcggtaaa accagtcggg aagagtattg gcattgccag tgttgatgtc aagctgtttg
    12301 agaatgtcgt taaattcacc agcttcaaac gactttctca gttgctgtcg ctgaatcttg
    12361 ccaatggcag ttttgggaat tgccgacttt tcaaccggaa ccagatagtc tggattgacg
    12421 ccaatctttt gaacaacctc gctgcggatt tctttagtga gattgacaac ttctgtttca
    12481 tcggcgattg tgggactgaa aaagattgcc agtttatcag tatggtcact tacacccctc
    12541 acggctacag ctgcggtata tgaaacctct acaccagaaa gctcttccac tgccgattca
    12601 atttcatgac tgtaatagtt gagaccatta ataattatga tatctttctg gcgaccagta
    12661 atggttagac gcccagagcg tagaaaccct aagtctccag tattaaacca accgtcagag
    12721 gtgaaaactt cctggttgaa ttccgggttt tgataataac cagaggtcac cgtcagtcct
    12781 ttgacttgca gaaaaccaat tgtgttttct tcaactactt ggttgttact atctataatc
    12841 cgcaccttaa ctccaggaat cggtgctcct acttccacaa acttttgctc gtctatcgtc
    12901 gagtcgagcg aaaagttgtg gtcaaaagtc acggcagaac tggtttcgga cattccccat
    12961 gccgggtgca tggcaattgc aggcagtcct tttggagcca gcaactgcaa aaactttctg
    13021 gcatgtttgg caacaattgc ctcgcccgca ttcaaaataa atcgcatctg tgagagatcc
    13081 caacgacgca agctgatctc agatgcccga tcgttgatca gcccataagc gaagttaggt
    13141 gcccaggtaa ttgtggctcg atagagctca atccaatcta accataacag tggatcttgc
    13201 agaaccaatt gagtgggagc atgaatttgt tggcaaccga gataaacatc gcgaatatgg
    13261 aacatcacca gaccgccaac atggtctagt ccaaaccaat ttaacgagat atctaggctt
    13321 gtaaaattat tggcttgagc ggtagcagcc gaacggctta aaagagcgcg atggctctgc
    13381 atcaccgctt tggaaatgcc tgtgctgcca gaggtcaaaa gtaaaattgc taaatcttct
    13441 ggctggcatt gataccaatt tcgatctggt tcacttgagc gcaaatcatc aaccgttgcc
    13501 agttgaaagt tttgtttctt caatctcttt gaccaagaat gaatcgcctc tgcttgggtt
    13561 gcacttgtca gtaccaaggg tcgtcccaac atcagccaag tattctccaa cttgcgcgta
    13621 gcactattgt cttgcgagta ggtcggggcg atcgctatcg gtactggaac aaagcccccc
    13681 agcacacagc cccaaaatgc agggatgaaa tcttgatttt gctgtaactg aaaaatcacc
    13741 ttgtcttgag gcttcaagcc cagctttctt aatcccatga gaattcgctg tgcttccagt
    13801 agtaagtccc cataaaattg acttatttca ctgccatcgg actggatgta gacgattcct
    13861 ttggttgggc tgtgtttagc tgcccgctct agggcacctg ctagagtcgt cggggcatca
    13921 gcaggaagtc gaagtagttc accatgactg atggctagct tatttgaccc caatttctcc
    13981 ttgaaagcct cccccacttg ggctgttgtt gctgcttgcg aactcctttc aacagcaact
    14041 tgacagttag gaagcaaatc tgatttgtgt agcggcggca agcaagacac ctgctcagta
    14101 actaccaccg ccacctgctc aacagagggc tgcttttgca attgctcttc ccatttttgc
    14161 accaattcgg aattaatcac ctcaagacga gctaaagctt gttcatctac ctgtcctgta
    14221 gccaacagtg gcaattgaga caacggcaca taagcgcacg gtagtatata agcgggtaaa
    14281 agggcttgca agtgggattg cagctgcttt ggattgaagg ctccttttaa aactacgtaa
    14341 gccaccaact gcgggccttc tatttctgtt tggcgcacta gcacccaagc atcctctaca
    14401 gaatgagccg ccaacaacgc tgcttccacc tctattagtt ctacccggta acctttgatc
    14461 caggtctgcc tgatgcttga gtctagcagt tccagtgtgc catcgttttg acggcgtccc
    14521 aactcacctg tcttgaacaa acgagcatcg ggggtctgtt ggaaaggatt tttaacaaag
    14581 cgtagcgccg tcttttcctc aggttggagg taaccgcgag ccaaacccgt accaccgaca
    14641 tagatttccc ccttcacccc gattggtact ggttgtaagt actgatccaa aacgtaaatc
    14701 ggtctgtaag tcggataacc aattggtaca gtctgctgag ttccaagttt ttcgcaagca
    14761 aagtaactta cctctccagc tgactcaggt aagctgtaaa gattgtgtag ctcggctgtg
    14821 aaatgcgctc taaacgcaag agctattgac tgatgcattg gctctccact gcaaagaacc
    14881 aaacgcaatg aattcaagcg ggttactaaa tcctcaccta cggactcaat aaaagacgat
    14941 agggctgaag ggacaaaacc aactatactg accttttgtc tggcaatcaa gtgctgcaag
    15001 tagattggat cgtcttggct gtttgcggcg gcaattatca aacgtccccc attaactaga
    15061 ggccagaaga tttcccaaac tgctgtatct tgagctaaag gagctttgtg taacacagca
    15121 tcagtaaaag acagagcaaa agtctgttgc agccaatcca aacggtaacc taccgcacaa
    15181 tgctctacta aaatccctcg ccgagacgaa tagagaacat aagcaaggtt tccaggtgtt
    15241 gccccacttt ttgggttctc cttgctttgt tgtgcaattt tctccgtatc tgagttgaaa
    15301 gaaattactg tcgtcttata ttttggcaag catcccaaca aatactgttg cgtcagtagt
    15361 accgacacct ttgcgtcttc tagcataaac gccaatcggt cttgaggata tgctggatca
    15421 agcggtaaat aagcgccacc tgccttaaga atacccagca gtcccactac ctgctctaag
    15481 gagcgctcca aacacaaccc aactagcacc tctggtttca cacccaatga ccgcagatag
    15541 tgcgctaatt gatttgcttt tgtgttcaac tcgtggtatg taagaatttc atcttcaaac
    15601 accactgcta ccgcgtcggg cgtccgctcc acctgcgctt caaataactc atggatacac
    15661 agttgttggg gatgttctac tgttgtatca ttccattcca ccaacaactg gtgccgttca
    15721 gcactactca gcagcggaat atctgatagc ttttgatggg gattaacaac aatcccctct
    15781 agcagtgttt gaaaatgctt agccattcga gtgatcgttt cagcattaaa caaatcactg
    15841 ttgtatttcc aaatacctct gagtggttct ttgacatcaa aaattgtcaa agttaaatca
    15901 aaagcagccc cttttgactc tggagttata gactccacaa ttaacccatc actatccata
    15961 agtgatgctt gtccgtcacc ctgatgagaa ccctcccagg cgagcgccac ttgataaagt
    16021 ggtgaacggc ttgggtctct ttccggttgc aatcgctcga ccagcaccgg gaagggatag
    16081 tcttgatgtt ctagcgcacc taatatacaa gagcgtactc ggcaaagcaa ctctcgaaat
    16141 gtaggatttc cagaaagatt cgctcgcaaa acaacgggat tagcaaggta accaacaatc
    16201 ttttcaaatt cagcaaggct gcgaccagcc attggagagc caattaagat atcttcttga
    16261 tttgtgtagc gtagtaatag tacctggaat gctgctagga tgattgtgta aagggttaca
    16321 ccttctgctt ttgctaattc caagagcttg tggattagtt tttcttccag aacaaaaggg
    16381 taggaagcgc cttcataagt ttgcactggt ggtctaggtc gatctattgg caaattcaat
    16441 atcggcaact caccagctaa ctgctcacgc caatagttcc acagccgctc tccttgttga
    16501 cttgctaaca tttggttttc ccaccgcacg taatctttgt attgcagggt ttggggtggg
    16561 agtgctacct cttgacctgt cttgaaagct tcataaaaag ccctaagttc actaacaagc
    16621 aattccaaag accagaaatc caccgctatg tggtgtaccg tcattagcag aaccacttcc
    16681 tttgctaccg atgcatctgt taaggtgttt gtgatcaaca gattaaagcg tattacgggt
    16741 tcgttgctca agtcaaaggg gcgaacgctt tcactcacaa gccagttgtg gaagtcattt
    16801 tggctccaat tagccgcttc ttggacacta aagcagactt cttgattttc ttgaatcgtt
    16861 tgcactggtt cgccatgctg tgcggtgtag gtagttctca gaactgaatg gcgctcaatc
    16921 aaagcgctcg ctgcctgtcg caatgctgga atatctacat tcgatactag acgtgctgca
    16981 tatgcaacgt tgtaagcagc actattgggt gctagttcgt ataagaacca aagcgctttt
    17041 tgcctatggg aaagagggtg agtttttgca gtgtcagtac gcttttgcag taagttgata
    17101 atttcttctt tatattgctt aatttccgtc aataactcag aggataatac atcttcggga
    17161 gcttcatagc acagtttgtc gccatcaacc cacaattcta tacctattgc caaaagattt
    17221 tggtagaact ctactaaatt cataactcac ctctaatcct gcttttctca gttaatgtag
    17281 ttgtgggtgc aacaaatgcc tttgaagtgg aattaacctt aacctcaaaa agttgctcgc
    17341 tcgccagttt tgttaaacca acgacactca aaccatccaa aaattttgtt atcgggatgt
    17401 ccactcctaa ctctgctctg agacgatttc taagttcgat aaccattagg gaatcaagtc
    17461 ccatttggtt cagaggctca tcaatgttta gcccagatgt agttattcct agagctttgg
    17521 caatctgttc tccaaggtaa gtaattaaca gtgattggct ttggtctttt gaattcgctt
    17581 ttatttggtc taaaagttgt ggggagttga ctttttgttg cttttgtgga atcgatttct
    17641 ctgcctgttg agctatttca gaaacgaagt tggggtaaga tgagcgtgag aattgctgca
    17701 aaaacttcga ccagttaact tgcatcaccc ctacctgagc cgcatcttgt ggtaacaaat
    17761 tttccagaat gcttagtgcc tgctgtgatt ctataggctt tatccccttg gttgcccatt
    17821 gaacctcacc cctgctacca acagcatttg ccatgcctac catcgaccac ggtccccagt
    17881 taatacttaa tcctggcaaa cttagcgacc tgcgataatc agccagagta tctaaaaagg
    17941 cattagcagc agcataattt gctaaacccg caggaccaag tatggatgcg gctgaagaaa
    18001 aaagcacgaa gaagtccaaa ggtaagtctt gtgtttgagt atgcaaattc catgctccac
    18061 taaccttagg tgcaaaaact ttggcaaaca gttgccattg atgatccacc agtcgtcgat
    18121 cttcaaacac accagcacta tggataatgc cccttaactg tggcattgat gttttgattt
    18181 gatttagtaa agaggtaact tcctgttctt gtgatacatc agtctgaatg actacaactt
    18241 gagttcctac ctcttcaagt ctccttagga tttctgtggc cgctgagtca ggtctgctac
    18301 gccctaccag aactaagtgc tttgccccat ggtctaccat ccattgtgct accagtaaac
    18361 caatcccacg aagaccacct gtgattaggt aagtagcatc ggcttttagc tgcaaagatt
    18421 ttttgacaat tttatcgctg cgtactaatc ggttaacata ccgttgcccg ttgcgaaaag
    18481 ctatatgatc accactagtt ggcttgggtg aacaaatttc tgcaaaaagg ctctgtgcat
    18541 tgttatttcc ttgtggatct agatctacca gggtacagtt aaattctgga tgctcatctt
    18601 taattacttt tcctaatccc cacacaggcg attgggctac cccaacaaga gtagattcta
    18661 tactcactcg ttgggctcct tttgtcacca gccataaggt aggaggcgga gaaaattctt
    18721 tactaattaa agactggaat agggacaaga cacctccaca tcctgtttgc gagacaactt
    18781 ctaagtctgc tactgttaag gcgtctgccg aaactgtatc tatgctccac aaataaacca
    18841 ctccacgcca ggaagtttta tcgcaagcca cttgttcaag tagtaattgc tgaaagtctt
    18901 ttggtaaggc tgggttgatg ctgaactctt gctctgctat ctgtttatac tccgtaccag
    18961 ggtagacgag gatacaagct tgttgttgcg atcgcaaaag tccacttaac tcctgaccaa
    19021 taccttgatt atcagcaaaa attaaccaac ttcctggttc tgttttggtt tcctgtagtt
    19081 tagctgcttg agctagaatc accgcttgct gagatacgtt tcctgcataa cttgggacaa
    19141 ttgttgctac atctttaaag ccagtattat gtaataactt ctgccaactc ttagttgtca
    19201 gcaatgggta gttgggtcgc aactgcaaat caccgaagcg ccaccaccca tctgtgagtc
    19261 cgaaaattaa atccaaccag cgtgatttaa gagtcccttc cagcagcaat aacatccctt
    19321 gaggagctaa taagttttgt acatgctgca aggtcacttg caaatctttg gtagcgtgca
    19381 acacgttagc tgccacaatt aaatcgtact tatgctgctc aaatccttgt aactgcggat
    19441 ctttttcaat gtccaataac tgataattga caaaggaaaa attttgaaac ttttgtttcg
    19501 cctgagcaag gaataaagga gatagatcag taaagacata ttctgtctgc tgggcattga
    19561 aagatggcag taggtaagag gtggttcccc ctgttccggc accaatttct aatactcgca
    19621 gtgtacgtcc tgatggcaaa tcttttagta ctgataaaac agcctgttgc atcagggtgt
    19681 tcatcacttt cgcccctggt gaatcctgat acagcccggc tgctgtggtt aagtcgcctt
    19741 cgggaaatag caaatccagt ggattacatt gtccctgtag cacttgtgct aaatttgacc
    19801 cacaccgatg taacagggtg agttcagcct tggcgtttgg gtatttagat aataggtcac
    19861 ctatctgtga ttgggggtgc tgtatcttag gcacttctac cacatgccat tgttcgccct
    19921 tgcactcgag tatcccaact tccacaagca tttccaacag acgatgcatt agccgcgagt
    19981 gttggctgac tacatccaac tgccgcacta tttttgcagc acaaaagcct tgccccaact
    20041 gaaagttcca tcccatttct tggaatgctg tgactacata ggcaacactc aaagcttcca
    20101 gttgaactaa tgcttcccca tataattgat aatgctgcga catcaactgc tctgcttgag
    20161 gctctaggat ctcgcgaatt tcttcggaag caggtatata atctccaatt gactgctgct
    20221 gtatactccc ttgagatcgc caaactattt cgtagcacaa gtcttggata aagtctggta
    20281 tgtggtgttg cttgtgttcc ctgactaaga ctgataatag ttcgggcagt aattttatct
    20341 gttcagaaga aaaatttcct gatgaaagca ctaactgagc taactgttca atattctccg
    20401 cctcaagcaa gttagtgata cgactttggc tattttctcc agataaagac tctgcttgtt
    20461 gatatctttg ttcaaaagtt tcaatccaat agcgttgccg ctcaaaggga taagttggca
    20521 agcttattaa ctctcgccta tagtccctgt caaaactaga ccagtctaca ggtactccac
    20581 aggtatataa ttttcctaaa ctctggagta aaagcttcca atcatcctgc ccttgtcgca
    20641 agcttgggag cattacgcct actccttctg gaaaacagtt gcgccccatc cccaacaagg
    20701 taggttttgg cccaatctca acaaatatct cataacccaa agcgtgaagc gtttttaaac
    20761 tgtcagcaaa tcgcacacag gatcgtaaat gtttccccca atactcaggc gtaatatctt
    20821 ctttagttaa tcgttctgct gtcaaattgg agattaaatc aatttgagga gcagcatatg
    20881 tgatactagc agcaatttga tggaattctg ccagcattgg ctccatcagc ggtgagtgga
    20941 aggcatggga aacttgtagc ttttttgtct taattccctc tgcttccaac gcgatacaaa
    21001 ttgacaaaac tgcctgccgc tctccagaaa ttacagtatt ctcaggtgta tttatagcag
    21061 caatagatat tttttcattg tttatttcag taatagcccg tatagtctct tctgccgcaa
    21121 acactacagc catttctcct tcaggcggca aactctgcat caggcggctt ctttgggcaa
    21181 ccagtttcag tccatcttcc aggctcaaga ctcctgccac agttgcagca acgtattctc
    21241 ctaaactatg acccattacg gcagtgggta cgatacccca agatttccat aactgagaga
    21301 gtgcatattc aatggcaaat aaagcaggtt gggtgtaagc ggtctgatca agtggcgaag
    21361 tctctcctgc ttcagggtaa agaacggtta gcagtgactt acccagatag gaacgtaata
    21421 tttcatcaca acggtctaag gtttgccgaa agatgggcgc agtttcgtag agttggcgtc
    21481 ccatgccaat atattgcgaa ccttgtccag tgaataaaaa tgctactttt ggacgcttct
    21541 tgctttttac ctgaccactg acaactgtgg tagtctcccc cgaagccgta aaaccagata
    21601 gttcttgttg caactgcacc ttagattcag caactacggc aaggcggtag tcaaaatgcg
    21661 tacgccctgt attggcagta aagcaaacat ctgctagcaa cacttcagaa tggttcaaaa
    21721 gaaattcctg ataacgttgc gccatctcta agagtgcttt ctcactttta actgacaagg
    21781 tcagaagatg cacaggacgt tcaataactt ctttcttttg acccttcgct tcgctcaagg
    21841 gcatactttg gacttttgac cctaccctcc aggcgtctac gcttcgctca agggcatgct
    21901 tttgactttc tagtggtgct tctgccaaaa ccacgtgagc atttgtgccg ccaaaaccaa
    21961 aggaactgac tccagctatt gctaaatcat ttccttgcgg ccaaggctcc aaggtttgtt
    22021 gaactcgtag cggcagttta tcaaagggaa tataaggatt tggcttttgg aaatgcaggc
    22081 ttggtggaat ttgtcgatgt ttaagagata acgccacttt aatcaatcca gcaattcccg
    22141 ctgctgcttc taagtgacca atattagttt taaccgaacc tacagcacag tagtttccac
    22201 cggctcgatc ctctgccaac acctctccca aagcgttcat ttctataggg tctcccagcg
    22261 atgtgcctgt accatgagct tcaatgtact gcacctgact aggcgagata cctgaaagtt
    22321 ggtaagcaga gcgcagaaca gctgactgtg cctgtggatt tggagcggta agtccattgc
    22381 tacgcccatc ctggttgact gcgcttcccc taatgacagc gtaaatgcga tcgcagtcag
    22441 ctaaggcttg cgatagaggt tttaaaatca ccacacctcc cccttcacca cgaacataac
    22501 catctgctcg ggcatcaaag gttttgcaac gaccgtcagg agctaaaaac cctgctttgg
    22561 cgaagttagc tgtaactttt ggcaacaata aggcattcac tcctccagct accgcaagag
    22621 tagactcttg gttccataag ctaagacaag catagtgaac cgcaacgagt gaagaggagc
    22681 aagccgtatc aaacgctacg cttggtccag tgaaattaaa cacataggaa atacggttag
    22741 ctgctatgga atgagaagtc ccagtggtca tataaatgtc ttgaccggaa ttgccccatg
    22801 tcaatacaga aaaatcaggg gttgatattc caataaagac acctgtttgc gtacctgcta
    22861 aatgcttcgg tatttgccca gcatcttcta atgcttccca ggtaatctcc agtagcaagc
    22921 gctgctgggg gtctatatta ccggcttctc gtgaagaaat accaaagaac ttcgggtcaa
    22981 actgatctac ctgctctaga aaaccgcccc aacgagtatt tgttttatct aatttttctg
    23041 tatctggatt taagtcccac cgagaaggag gcatttctgt aatagcatcc acaccgtcgc
    23101 gcagcagatg ccaaaaagcc tctggactat tagctttagg aaaacgacat cctattccaa
    23161 taatggcgat tggttctcta ttcattctct tggttcttgt aattaattag cttcatttca
    23221 tcaatacctt caccaattta cgaggacgag ttgatgtacc taacttttcc cgttaagtct
    23281 ggaaacatgg atatagtaag ggtttcagtc cacaagccta ttatcgataa aagacgttta
    23341 atgagaataa aacaacggaa aaataggact tttaggatag cactcttgat cgcgatcgct
    23401 gtgatagaaa gataacggga aaagtcaggt tgatgtacaa actcccatct ttccgaagct
    23461 aggcaaaaac aataatacct aaaaattact tttaggtttc tcgcaaggtt tttttagtag
    23521 atttcacgta gtatcaaggg tttgagagtt caatccatct tgtaaactaa acgcttattt
    23581 atcaatgatt ttggcagttt cgccaaaatt tttgtaggct tttatttggt ctaaggtatt
    23641 gtttcataca tttacttaaa cactaactga agaggttatt gattgtaata acagacattg
    23701 ggctgctaag tactgagcaa acgcttcaat gttggggtat ctccaaaaaa gggtcggctc
    23761 aagttcacag ccagtccact gtgctaattc acccgtcata ctaactgcca ccgccgaatc
    23821 tagaccgtat gcagcaaaag gctcctgaat atctatctca tccggggaca ctcgcaggga
    23881 cagggcgaga tgagaaacta gccaagttgc gatcgcttct tctgtaaaag ctggtttgaa
    23941 ggatttttca tcagcttgtg actcatcttc tgaatgtact ttctcccaaa gggcttctac
    24001 ttcttgtggg agttgtagta agttttgttc aagacttgct gtccaatctc cgactacatc
    24061 caaacttcca ttcaaaaaac catcccgaca tgcatggcgc tgaatcttac cactggatgt
    24121 tttcgggata ctggctgtct tcagtagcac aacagcataa acttgtagtt ggtgctgctc
    24181 ggacactgct tgacgaatac ccctaactac ctgatctaca tttaactggc gtaagtaact
    24241 ccgctctacc tcttgaacaa tgactaaccg ttcaacacct tctacctcca tagaaaatgc
    24301 tgccccgcaa ttcggtcgca gtgctgaatg actcgtttgg actgtcaatt caatatcttg
    24361 aggataataa ttttgccccc ggatgataat cacgtcttta atccgacccg tgatgaataa
    24421 ctcgccatca agcaaaaatc ctaaatctcc tgtgcgtaaa aacggccctt ctccagtatc
    24481 taccaaatat gcctgaaagg tttgctcagt cgcttgattt cgcatccaat aaccttgggc
    24541 gaccgtagtg cctgacaccc aaatttctcc tacttctcca ggagaacagg ttgtcaatga
    24601 ttctggatgc acaatcgcaa ttttcgtatc aatttcggta tatccacatc ccacgagagt
    24661 taccgaccct ggctcttgtt cttgagcctc taccacacga ttttgtctga gtgcctctga
    24721 ttgaactgta taaaaagtgg gtaagtcttt ggctctagta gcagttacct taagagtagc
    24781 ttcagctaaa ccataaccag ggcagaaagt tctaaggtta aaaccacacg gtttgaacag
    24841 ttcggcaaac cgtttgagaa catctgctct aactggctca gcaccgttaa gagccatacg
    24901 ccaactgctt aaatctaaag tggcgagttg ttctgaggtg accttatcta cgcatagttg
    24961 ataggcgaag ttgggagcac cgctatgagt tgctttgtag cgtgaaatcg cctcaagcca
    25021 tcgcattggt cgcatcagaa aggatgtggg agccatcatg taacatggaa ttcctttata
    25081 tagcggttga atggctccat agatgagtcc catatcgtga aaagtaggaa gccatgtgac
    25141 tatgacgctt tctgaggtgt gatcccatcc tctgtcaagg tctgctgaat tagacagtaa
    25201 attgccatga ctcaccatta caccttttgg tgttcccgta gaacccgagg tgtactgcaa
    25261 aaatgccaaa gtgtcgctat ttatttttaa aggctgccaa tcttctgcaa agttgttggt
    25321 aatattttca gtagctatgt aatgcaaagc tgctagttct ggttcttgtt ttatactgtg
    25381 ttcaatattg gtaagcacag atgttgttgt gagggcgaaa ctagcttcgg catctttgac
    25441 aatcgcttgc aaccttgtca tgcgctgatt gcggcgtggt ggatatacgg gaacagcagt
    25501 aacacctgcg tacagacacc cgaaaaaagc ttcaataaat tcgagtcctg gcgggtataa
    25561 aagcagcgct ctttctccag tagctttcat gctgtgtaag aaagcagcaa gcgatcgcgc
    25621 tttttggtct aatgcttgat aagttaagct aacttcttgt gcttctccat ctaccaaaaa
    25681 ggtatatgct acttgctttg gttgctgtaa cgctcttttg cgtaacaggt caaccaaagt
    25741 cgcttcactg aaagtgggta ctgaaaataa attgttgttc at
//
