BGC0001468: bicyclomycin biosynthetic gene cluster from Streptomyces cinnamoneus
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Location: 5,989,046 - 5,998,011 nt. (total: 8,966 nt).
This entry is originally from NCBI GenBank PKFQ01000001.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
Operons
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001468
Short description bicyclomycin biosynthetic gene cluster from Streptomyces cinnamoneus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (trna-derived)
Loci
PKFQ01000001.1
5989046 - 5998011
via Enzymatic assays, Heterologous expression
Compounds
  • bicyclomycin
Species Streptomyces cinnamoneus [taxonomy]
References
Chemical products information
bicyclomycin [synonyms: bicozamycin, aizumycin] Evidence:
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C12H18N2O7
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CYQ11_26520
  • PPT15944.1
  • bcmG
 5989046 - 5989948 (-) 2OG-Fe(II) oxygenase
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    • CYQ11_26525
    • PPT15945.1
    • bcmF
    		 5989945 - 5990835 (-) 2OG-Fe(II) oxygenase
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      • CYQ11_26530
      • PPT16816.1
      • bcmE
      		 5990877 - 5991821 (-) 2OG-Fe(II) oxygenase
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        • CYQ11_26535
        • PPT15946.1
        • bcmD
        		 5991821 - 5993287 (-) cytochrome P450
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          • CYQ11_26540
          • PPT15947.1
          • bcmC
          		 5993284 - 5994201 (-) 2OG-Fe(II) oxygenase
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            • CYQ11_26545
            • PPT16817.1
            • bcmB
            		 5994191 - 5995168 (-) isopenicillin N synthase family oxygenase
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              • CYQ11_26550
              • PPT15948.1
              • bcmA
              		 5995171 - 5995896 (-) tRNA-dependent cyclodipeptide synthase
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                • CYQ11_26555
                • PPT15949.1
                • bcmT
                		 5996589 - 5998010 (+) MFS transporter
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                  Biosynthesis information
                  Operons
                  Genes Evidence
                  bcmT
                  Annotation changelog

                  Entry version: next

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2024-04-23
                  MIBiG v4 annotathon
                  • (ID: EMAUK5TYS6O5PLPCDCIRFTNF)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 4

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Merged extra publication from duplicate entry BGC0001530
                  • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated compound(s) information (NPAtlas curation)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2018-08-06
                  Submitted
                  • (ID: M427BTTCY4TXAJBSTYWV5UDQ)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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