BGC0001471: saalfelduracin biosynthetic gene cluster from Amycolatopsis saalfeldensis
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Location: 708,690 - 737,346 nt. (total: 28,657 nt).
This entry is originally from NCBI GenBank NZ_FOEF01000002.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001471
Short description saalfelduracin biosynthetic gene cluster from Amycolatopsis saalfeldensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "As we are waiting on publication, we do not have a DOI/PMID for article associated with this cluster (Step 2). A related publication from our lab has been used to allow for MIBiG submission while this publication is finishing the review process."
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: NZ_FOEF01000002.1
Compounds
  • saalfelduracin
Species Amycolatopsis saalfeldensis [taxonomy]
References
Chemical products information
saalfelduracin
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C69H76N18O18S6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BMY97_RS07420
  • WP_091614342.1
 708692 - 709702 (-) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
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  • BMY97_RS07425
  • WP_177231217.1
 709707 - 710135 (-) ester cyclase
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  • BMY97_RS07430
  • WP_177231218.1
 710179 - 711417 (-) acyl-CoA/acyl-ACP dehydrogenase
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  • BMY97_RS07435
  • WP_177231219.1
 711434 - 712270 (-) SAM-dependent methyltransferase
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  • BMY97_RS07440
  • WP_091614353.1
 712267 - 712830 (-) DUF2867 domain-containing protein
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  • BMY97_RS07445
  • WP_177231220.1
 712874 - 713917 (-) alpha/beta hydrolase
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  • BMY97_RS07450
  • WP_091614358.1
 714479 - 714664 (+) thiocillin/thiostrepton family thiazolyl peptide
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  • BMY97_RS07455
  • WP_143086144.1
 714784 - 715575 (+) alpha/beta fold hydrolase
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  • BMY97_RS07460
  • WP_091614364.1
 715572 - 718226 (+) lantibiotic dehydratase
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  • BMY97_RS07465
  • WP_091614367.1
 718223 - 719224 (+) hypothetical protein
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  • BMY97_RS07470
  • WP_177231221.1
 719230 - 720333 (+) hypothetical protein
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  • BMY97_RS07475
  • WP_091614372.1
 720330 - 721949 (+) hypothetical protein
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  • BMY97_RS07480
  • WP_091614375.1
 721946 - 723592 (+) hypothetical protein
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  • BMY97_RS07485
  • WP_177231222.1
 723589 - 725517 (+) TOMM precursor leader peptide-binding protein
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  • BMY97_RS07490
  • WP_143086145.1
 725495 - 726823 (+) cytochrome P450
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  • BMY97_RS07495
  • WP_091614382.1
 726799 - 728094 (+) acyl--CoA ligase
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  • BMY97_RS07500
  • WP_091614385.1
 728091 - 729272 (+) cytochrome P450
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  • BMY97_RS46895
  • WP_091614387.1
 729260 - 731740 (+) lantibiotic dehydratase
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  • BMY97_RS48260
 731744 - >731849 (+) polymer-forming cytoskeletal protein
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  • BMY97_RS46900
  • WP_245787193.1
 731851 - 732264 (+) hypothetical protein
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  • BMY97_RS07515
  • WP_091614389.1
 732264 - 733454 (+) YcaO-like family protein
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  • BMY97_RS07520
  • WP_091614392.1
 733461 - 734825 (+) TfuA-like protein
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  • BMY97_RS07525
  • WP_091614395.1
  • tsrT
 734822 - 736543 (+) tryptophan 2-C-methyltransferase
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  • BMY97_RS07530
  • WP_091614398.1
 736540 - 737343 (+) SDR family NAD(P)-dependent oxidoreductase
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RiPP-specific information
Subclass Thiopeptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: JW4IUWLB4KKWRZXPXDMX77W3, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Updated coordinates from duplicate entry BGC0002023
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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